Okumura Masaki 奥村正樹

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OKUMURA MASAKI 奥村正樹

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Researcher Number	50635810
Other IDs
Affiliation (Current)	2025: 東北大学, 学際科学フロンティア研究所, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 東北大学, 学際科学フロンティア研究所, 准教授 2017 – 2021: 東北大学, 学際科学フロンティア研究所, 助教 2016: 東北大学, 多元物質科学研究所, 助教 2015: 東北大学, 多元物質科学研究所, 特別研究員(PD)
Review Section/Research Field	Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Complex systems / Medium-sized Section 37:Biomolecular chemistry and related fields / Transformative Research Areas, Section (II) / Science and Engineering / Biological Sciences / Basic Section 43020:Structural biochemistry-related / Biophysics Except Principal Investigator Transformative Research Areas, Section (II) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator 酸化的フォールディング / PDI / 小胞体 / oxidative folding / ジスルフィド結合 / PDIファミリー / シャペロン / 分子認識 / 高速AFM / LLPS … More / カルシウム / PDI family / P5 / NMR / フォールディング / 溶液散乱 / 蛋白質品質管理 / メゾスケール構造体 / 分泌経路 / セクレトーム解析 / 溶液構造解析 / レドックス / 液滴 / 化学制御 / 相分離 / protein assembly / レドックス反応場 / potein assembly / 活性亢進剤 / 反応遅延制御 / HPLC / 細胞内酸化的フォールディングモニタリング法 / セミインタクト細胞 / 分子夾雑 / 凝集抑制 / MHCクラス1 / cell free system / 品質管理 / MHC / IRE1 / SAXS / 二量体化モチーフ / X線小角散乱法 / タンパク質品質管理 / プロウログアニリン / folding intermediate / 前駆体蛋白質 / フォールディング中間体 / folding … More Except Principal Investigator フォールディング / ミスフォールディング / タンパク質 / 超分子化学 / 遅延制御 / NMR / 常磁性タグ / フォールディング中間体 / 小胞体 / シャペロン / タンパク質フォールディング Less

小胞体内の相分離区画を摂動する酸化還元の理解と化学制御Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Tohoku University
分泌経路におけるメゾスケール構造体プロファイリングの開拓Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Tohoku University
小胞体内液液相分離の作用機序解明と化学的制御Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Tohoku University
Organization of kinetics-driven supramolecular chemistry
- Principal Investigator
  
  Muraoka Takahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tokyo University of Agriculture and Technology
Elucidation of the mechanism of kinetically controlled reaction fields in cellsPrincipal Investigator
- Principal Investigator
  
  Okumura Masaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tohoku University
Structural basis for recognition and regulation of protein folding intermediate by molecular chaperones in the endoplasmic reticulum
- Principal Investigator
  
  SAIO Tomohide
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokushima
分子夾雑環境における酸化的フォールディングのモニタリング法の開発Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Understanding the protein homeostasis mechanism by P5, a member of the PDI familyPrincipal Investigator
- Principal Investigator
  
  Okumura Masaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Tohoku University
小胞体内MHCの立体構造構築の理解Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Understanding the folding intermediate recognition mechanism by PDIPrincipal Investigator
- Principal Investigator
  
  OKUMURA MASAKI
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Tohoku University
酵素基質相互作用を決定する動的構造制御Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tohoku University
分子認識による酸化的フォールディングの1分子観察Principal Investigator
- Principal Investigator
  
  奥村正樹
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book Patent Other

[Book] 月刊細胞特集「LC（Low-Complexity）ドメインの生物学」2024
- Author(s)
  渡部マイ, 金村進吾, 李映昊, 奥村正樹
- Total Pages
  78
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-23KK0105
[Book] 月刊細胞特集「LC（Low-Complexity）ドメインの生物学」2024
- Author(s)
  渡部マイ, 金村進吾, 李映昊, 奥村正樹
- Total Pages
  78
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23K23472
[Book] 月刊細胞特集「LC（Low-Complexity）ドメインの生物学」2024
- Author(s)
  渡部マイ, 金村進吾, 李映昊, 奥村正樹
- Total Pages
  78
- Publisher
  北隆館
- Data Source
  KAKENHI-PLANNED-21H05095
[Book] 小胞体ジスルフィド結合触媒ネットワークを支える酵素群の構造基盤2022
- Author(s)
  金村進吾, 稲葉謙次, 奥村正樹
- Total Pages
  2
- Publisher
  日本結晶学会誌 64，209-210
- Data Source
  KAKENHI-PLANNED-21H05095
[Book] 小胞体ジスルフィド結合触媒ネットワークを支える酵素群の構造基盤2022
- Author(s)
  金村進吾, 稲葉謙次, 奥村正樹
- Total Pages
  2
- Publisher
  日本結晶学会誌 64，209-210
- Data Source
  KAKENHI-PROJECT-23K23472
[Book] 高速原子間力顕微鏡により明らかにされたプロテインジスルフィドイソメラーゼ（PDI）の構造ダイナミクス2020
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  生化学会　みにれびゅう
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Book] 高速原子間力顕微鏡により明らかにされたプロテインジスルフィドイソメラーゼ（PDI）の構造ダイナミクス2020
- Author(s)
  奥村　正樹、稲葉　謙次
- Total Pages
  6
- Publisher
  生化学会誌みにれびゅう
- Data Source
  KAKENHI-PROJECT-19K06520
[Book] 小胞体におけるMHCの品質管理2020
- Author(s)
  金村進吾, 松崎元紀, 前仲勝実, 稲葉謙次, 奥村正樹
- Total Pages
  8
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Book] 高速原子間力顕微鏡により明らかにされたプロテインジスルフィドイソメラーゼ（PDI）の構造ダイナミクス2020
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  生化学会　みにれびゅう
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Book] 小胞体におけるMHCの品質管理2020
- Author(s)
  金村進吾, 松崎元紀, 前仲勝実, 稲葉謙次, 奥村正樹
- Total Pages
  8
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Book] 高速原子間力顕微鏡により明らかにされたプロテインジスルフィドイソメラーゼ（PDI）の構造ダイナミクス2020
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  生化学
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Book] 生化学2020
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  生化学会
- Data Source
  KAKENHI-PROJECT-19K06520
[Book] 小胞体におけるMHCの品質管理2020
- Author(s)
  金村進吾、松崎　元紀、前仲　勝実、稲葉　謙次、奥村　正樹
- Total Pages
  8
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PROJECT-19K06520
[Book] 放射光利用の手引きー農水産・医療、エネルギー、環境、材料開発分野などへの応用ー細胞のタンパク質の立体構造を頑強にする仕組み2019
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  5
- Publisher
  アグネ技術センター
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Book] 月刊「細胞」エレクトロンバイオダイナミクスが支える生命の生存戦略2019
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-19K06520
[Book] 月間「細胞」構造生物学の最前線2019
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-19K06520
[Book] 放射光利用の手引きー農水産・医療、エネルギー、環境、材料開発分野などへの応用ー細胞のタンパク質2019
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  5
- Publisher
  アグネ技術センター
- Data Source
  KAKENHI-PROJECT-17K15098
[Book] PDI ファミリー酵素群の構造ダイナミクスに基づく機能制御2019
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  北隆館、月刊「細胞」エレクトロンバイオダイナミクスが支える生命の生存戦略
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Book] 高速原子間力顕微鏡を用いた酵素の触媒機構の可視化：PDIファミリーを例に2019
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  6
- Publisher
  北隆館、月間「細胞」構造生物学の最前線
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Book] Oxidatve Folding of Peptides and Proteins 2nd Edition2018
- Author(s)
  Okumura, M., Watanabe, S., Inaba, K.
- Total Pages
  25
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Book] Structural insights into disulfide bond formation and protein quality control in the mammalian endoplasmic reticulum2018
- Author(s)
  M. Okumura, S. Watanabe, and K. Inaba
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-17K15098
[Book] Structural insights into disulfide bond formation and protein quality control in the mammalian endoplasmic reticulum2018
- Author(s)
  M. Okumura, S. Watanabe, and K. Inaba.
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Book] アルツハイマー病ー発症メカニズムと新規診断法・創薬・治療開発2018
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  5
- Publisher
  NTS
- Data Source
  KAKENHI-PROJECT-17K15098
[Book] Oxidatve Folding of Peptides and Proteins 2nd Edition2018
- Author(s)
  Okumura, M., Watanabe, S., Inaba, K.
- Total Pages
  25
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-17K15098
[Book] アルツハイマー病ー発症メカニズムと新規診断法・創薬・治療開発2018
- Author(s)
  奥村正樹、稲葉謙次
- Total Pages
  11
- Publisher
  NTS
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Book] X線小角散乱解析が明らかにしたPDIファミリータンパク質ERp46及びPDI酸化酵素Ero1αの構造ダイナミクスと機能2017
- Author(s)
  金村　進吾、奥村　正樹、稲葉　謙次
- Total Pages
  3
- Publisher
  分子研レターズ
- Data Source
  KAKENHI-PROJECT-17K15098
[Book] X線小角散乱解析が明らかにしたPDIファミリータンパク質ERp46及びPDI酸化酵素Ero1αの構造ダイナミクスと機能2017
- Author(s)
  金村　進吾、奥村　正樹、稲葉　謙次
- Total Pages
  3
- Publisher
  分子研レターズ
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Book] ERp46とPDIの異なる構造と機能的役割2015
- Author(s)
  奥村正樹、金村進吾、稲葉謙次
- Total Pages
  3
- Publisher
  生物物理
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Journal Article] Client recognition differences between PDI and ERp46 to guide oxidative folding2024
- Author(s)
  Saio Tomohide、Ishii Kotone、Matsusaki Motonori、Kumeta Hiroyuki、Kanemura Shingo、Okumura Masaki
- Journal Title
  
  bioRxiv
  
  Volume: 2024.03.04 Pages: 583432-583432
- DOI
  10.1101/2024.03.04.583432
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0105, KAKENHI-PLANNED-21H05095
[Journal Article] Enzymatic and synthetic regulation of polypeptide folding2024
- Author(s)
  Muraoka Takahiro、Okumura Masaki、Saio Tomohide
- Journal Title
  
  Chemical Science
  
  Volume: 15 Issue: 7 Pages: 2282-2299
- DOI
  10.1039/d3sc05781j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0105, KAKENHI-ORGANIZER-21H05093, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-23K23472
[Journal Article] Oxidative Protein Folding Promotion by Imidazoyl-conjugated Thiol2023
- Author(s)
  Okada, S., Matsumoto, Y., Okumura, M., and Muraoka, T.*
- Journal Title
  
  Chem.Lett.
  
  Volume: 52 Pages: 202-205
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21H05095
[Journal Article] Semi-enzymatic acceleration of oxidative protein folding by <i>N</i>-methylated heteroaromatic thiols2023
- Author(s)
  Okada Shunsuke、Matsumoto Yosuke、Takahashi Rikana、Arai Kenta、Kanemura Shingo、Okumura Masaki、Muraoka Takahiro
- Journal Title
  
  Chemical Science
  
  Volume: 14 Issue: 28 Pages: 7630-7636
- DOI
  10.1039/d3sc01540h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K04933, KAKENHI-ORGANIZER-21H05093, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-23K23472
[Journal Article] Dose-response relationship for the resistance of human insulin to degradation by insulin-degrading enzyme2023
- Author(s)
  Okumura Masaki、Kuramochi Tsubura、Lin Yuxi、Furukawa Ran、Mizutani Kenji、Yokoyama Takeshi、Kim Mingeun、Lim Mi Hee、Yi Hyon-Seung、Arai Kenta、Yamaguchi Hiroshi、Hojo Hironobu、Iwaoka Michio、Tanaka Yoshikazu、Park Sam-Yong、Inaba Kenji、Kanemura Shingo、Lee Young-Ho
- Journal Title
  
  bioRxiv
  
  Volume: 2023.04.08. Pages: 536135-536135
- DOI
  10.1101/2023.04.08.536135
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0105, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-23K23464
[Journal Article] Oxidative Protein Folding Promotion by Imidazoyl-conjugated Thiol2023
- Author(s)
  Okada, S., Matsumoto, Y., Okumura, M., and Muraoka, T.*
- Journal Title
  
  Chem.Lett.
  
  Volume: 52 Pages: 202-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23472
[Journal Article] Cysteine-based protein folding modulators for trapping intermediates and misfolded forms2022
- Author(s)
  Nishino, H., Kitamura, M., Okada, S., Miyake, R., Okumura, M., and Muraoka, T.*
- Journal Title
  
  RSC Advances
  
  Volume: 12 Pages: 26658-26664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23472
[Journal Article] Cysteine-based protein folding modulators for trapping intermediates and misfolded forms2022
- Author(s)
  Nishino, H., Kitamura, M., Okada, S., Miyake, R., Okumura, M., and Muraoka, T.*
- Journal Title
  
  RSC Advances
  
  Volume: 12 Pages: 26658-26664
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21H05095
[Journal Article] Biophysical elucidation of neural network and chemical regeneration of neural tissue2022
- Author(s)
  Takahiro Muraoka, Tomohide Saio, Masaki Okumura
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0024
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21H05093, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-23K23472
[Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021
- Author(s)
  Okumura, M.,* Kanemura, S.,# Matsusaki, M., # Kinoshita, M., # Saio, T., Ito, D., Hirayama, C., Kumeta, H., Watabe, M., Amagai, Y., Lee, Y.H., Akiyama, S., and Inaba, K.*
- Journal Title
  
  Structure
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of co-translational disulfide bond formation2021
- Author(s)
  Hirayama, C., Machida, K., Noi, K., Murakawa, T., Okumura, M., Ogura, T., Imataka, H., and Inaba, K*.
- Journal Title
  
  iScience
  
  Volume: 4 Pages: 102296-102296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of co-translational disulfide bond formation2021
- Author(s)
  Hirayama, C., Machida, K., Noi, K., Murakawa, T., Okumura, M., Ogura, T., Imataka, H., and Inaba, K*.
- Journal Title
  
  iScience
  
  Volume: 4 Pages: 102296-102296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021
- Author(s)
  Okumura M, Kanemura S., Matsusaki M., Kinoshita M., Saio T., Ito D., Hirayama C., Kumeta H., Watabe M., Amagai Y., Lee Y. H., Akiyama S. and Inaba K.
- Journal Title
  
  Structure
  
  Volume: 29 Issue: 12 Pages: 1-14
- DOI
  10.1016/j.str.2021.03.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-20J11932, KAKENHI-PROJECT-19K06520, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PUBLICLY-19H04945, KAKENHI-PLANNED-21H05253
[Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021
- Author(s)
  Okada Shunsuke、Matsusaki Motonori、Okumura Masaki、Muraoka Takahiro
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 4 Pages: 879-879
- DOI
  10.3390/molecules26040879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15969, KAKENHI-PROJECT-19J00893, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19H02828, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095
[Journal Article] Visualization of structural dynamics of protein disulfide isomerase enzymes in catalysis of oxidative folding and reductive unfolding2021
- Author(s)
  Okumura M, Noi K, and Inaba K*
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 66 Pages: 49-57
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021
- Author(s)
  Okumura, M.,* Kanemura, S.,# Matsusaki, M., # Kinoshita, M., # Saio, T., Ito, D., Hirayama, C., Kumeta, H., Watabe, M., Amagai, Y., Lee, Y.H., Akiyama, S., and Inaba, K.*
- Journal Title
  
  Structure
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] A unique leucine-valine adhesive motif supports structure and function of protein disulfide isomerase P5 via dimerization2021
- Author(s)
  Okumura, M.,* Kanemura, S.,# Matsusaki, M., # Kinoshita, M., # Saio, T., Ito, D., Hirayama, C., Kumeta, H., Watabe, M., Amagai, Y., Lee, Y.H., Akiyama, S., and Inaba, K.*
- Journal Title
  
  Structure
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021
- Author(s)
  Okada, S., Matsusaki, M., Okumura, M.,* and Muraoka, T.*
- Journal Title
  
  molecules
  
  Volume: 26 Pages: 879-879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021
- Author(s)
  Okada, S., Matsusaki, M., Okumura, M.,* and Muraoka, T.*
- Journal Title
  
  molecules
  
  Volume: 26 Pages: 879-879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Conjugate of Thiol and Guanidyl Units with Oligoethylene Glycol Linkage for Manipulation of Oxidative Protein Folding2021
- Author(s)
  Okada, S., Matsusaki, M., Okumura, M.,* and Muraoka, T.*
- Journal Title
  
  molecules
  
  Volume: 26 Pages: 879-879
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Visualization of structural dynamics of protein disulfide isomerase enzymes in catalysis of oxidative folding and reductive unfolding2021
- Author(s)
  Okumura M, Noi K, and Inaba K*
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 66 Pages: 49-57
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of nascent-chain disulfide bond formation2021
- Author(s)
  Hirayama, C., Machida, K., Noi, K., Murakawa, T., Okumura, M., Ogura, T., Imataka, H., and Inaba, K.*
- Journal Title
  
  iScience
  
  Volume: 4 Issue: 4 Pages: 102296-102296
- DOI
  10.1016/j.isci.2021.102296
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-17H04995, KAKENHI-PROJECT-20J11932, KAKENHI-PROJECT-19K06520, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] Functional Interplay between P5 and PDI/ERp72 to Drive Protein Folding.2021
- Author(s)
  Matsusaki M, Okada R, Tanikawa Y, Kanemura S, Ito D, Lin Y, Watabe M, Yamaguchi H, Saio T, Lee YH, Inaba K, and *Okumura M.
- Journal Title
  
  Biology
  
  Volume: 10 Issue: 11 Pages: 1112-1112
- DOI
  10.3390/biology10111112
- NAID
  120007168792
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] Ca2+ Regulates ERp57-Calnexin Complex Formation.2021
- Author(s)
  Tanikawa Y,# Kanemura S,# Ito D, Lin Y, Matsusaki M, Kuroki K, Yamaguchi H, Maenaka K, Lee YH, Inaba K, and *Okumura M.
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 10 Pages: 2853-2853
- DOI
  10.3390/molecules26102853
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-20K15969, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] Visualization of structural dynamics of protein disulfide isomerase enzymes in catalysis of oxidative folding and reductive unfolding2021
- Author(s)
  Okumura M, Noi K, and Inaba K*
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 66 Pages: 49-57
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] Distinct roles and actions of protein disulfide isomerase family enzymes in catalysis of co-translational disulfide bond formation2021
- Author(s)
  Hirayama, C., Machida, K., Noi, K., Murakawa, T., Okumura, M., Ogura, T., Imataka, H., and Inaba, K*.
- Journal Title
  
  iScience
  
  Volume: 4 Pages: 102296-102296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Solution NMR for investigation of liquid-liquid phase separation2020
- Author(s)
  Saio T*, Okumura M, Lee Y.H*
- Journal Title
  
  JKMRS
  
  Volume: 24 Pages: 47-52
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Biochemical characterization of ER-resident peroxidases, GPx7 and GPx8, reveals their different and regulated oxidative activities2020
- Author(s)
  Kanemura S., Sofia E., Hirai N., Okumura M., Kadokura H., and Inaba K.*
- Journal Title
  
  JOURNAL OF BIOLOGICAL CHEMISTRY
  
  Volume: 295 Pages: 12772-12785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Antipsychotic olanzapine-induced misfolding of proinsulin in the ER accounts for atypical development of diabetes2020
- Author(s)
  Ninagawa S*, Tada S,# Okumura M,# Inoguchi K,# Kinoshita M, Kanemura S, Imami K, Umezawa H, Ishikawa T, Okada T, Mackin R, Torii S, Ishihama Y, Inaba K, Anazawa T, Nagamine T, Mori K*
- Journal Title
  
  eLife
  
  Volume: 9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] PDI Family Members as Guides for Client Folding and Assembly2020
- Author(s)
  Kanemura, S, Matsusaki, M, Inaba, K, and Okumura, M.*
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Solution NMR for investigation of liquid-liquid phase separation2020
- Author(s)
  Saio T*, Okumura M, Lee Y.H*
- Journal Title
  
  JKMRS
  
  Volume: 24 Pages: 47-52
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] The Protein Disulfide Isomerase family: from Proteostasis to Pathogenesis2020
- Author(s)
  Matsusaki M, Kanemura S, Kinoshita M, Lee YH, Inaba K,* Okumura M.*
- Journal Title
  
  Biochim Biophys Acta-general subjects
  
  Volume: 1864 Pages: 129338-129338
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] PDI Family Members as Guides for Client Folding and Assembly2020
- Author(s)
  Kanemura, S, Matsusaki, M, Inaba, K, and Okumura, M.*
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] Biochemical characterization of ER-resident peroxidases, GPx7 and GPx8, reveals their different and regulated oxidative activities2020
- Author(s)
  Kanemura S., Sofia E., Hirai N., Okumura M., Kadokura H., and Inaba K.*
- Journal Title
  
  JOURNAL OF BIOLOGICAL CHEMISTRY
  
  Volume: 295 Pages: 12772-12785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Biochemical characterization of ER-resident peroxidases, GPx7 and GPx8, reveals their different and regulated oxidative activities2020
- Author(s)
  Kanemura S., Sofia E., Hirai N., Okumura M., Kadokura H., and Inaba K.*
- Journal Title
  
  JOURNAL OF BIOLOGICAL CHEMISTRY
  
  Volume: 295 Pages: 12772-12785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] Antipsychotic olanzapine-induced misfolding of proinsulin in the ER accounts for atypical development of diabetes2020
- Author(s)
  Ninagawa S*, Tada S,# Okumura M,# Inoguchi K,# Kinoshita M, Kanemura S, Imami K, Umezawa H, Ishikawa T, Okada T, Mackin R, Torii S, Ishihama Y, Inaba K, Anazawa T, Nagamine T, Mori K*
- Journal Title
  
  eLife
  
  Volume: 9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Solution NMR for investigation of liquid-liquid phase separation2020
- Author(s)
  Saio T*, Okumura M, Lee Y.H*
- Journal Title
  
  JKMRS
  
  Volume: 24 Pages: 47-52
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] PDI Family Members as Guides for Client Folding and Assembly2020
- Author(s)
  Kanemura, S, Matsusaki, M, Inaba, K, and Okumura, M.*
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Visualization of structural dynamics of protein disulfide isomerase enzymes in catalysis of oxidative folding and reductive unfolding2020
- Author(s)
  Okumura, M., Noi, K. and Inaba, K.*
- Journal Title
  
  Curr. Opin. Struct. Biol.
  
  Volume: 66 Pages: 49-57
- DOI
  10.1016/j.sbi.2020.10.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19K06520, KAKENHI-PUBLICLY-20H04688, KAKENHI-PLANNED-21H05095, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] Antipsychotic olanzapine-induced misfolding of proinsulin in the ER accounts for atypical development of diabetes2020
- Author(s)
  Ninagawa S*, Tada S,# Okumura M,# Inoguchi K,# Kinoshita M, Kanemura S, Imami K, Umezawa H, Ishikawa T, Okada T, Mackin R, Torii S, Ishihama Y, Inaba K, Anazawa T, Nagamine T, Mori K*
- Journal Title
  
  eLife
  
  Volume: 9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Journal Article] Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding2019
- Author(s)
  Shunsuke Okada, Motonori Matsusaki, Kenta AraiK , Yuji Hidaka, Kenji Inaba, Masaki Okumura, Takahiro Muraoka
- Journal Title
  
  Chemical Communications
  
  Volume: 55(6) Issue: 6 Pages: 759-762
- DOI
  10.1039/c8cc08657e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01925, KAKENHI-PROJECT-17K18123, KAKENHI-PUBLICLY-17H05147, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-17H04885, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-18H03978, KAKENHI-PLANNED-26116005
[Journal Article] Dynamic assembly of protein disulfide isomerase in catalysis of oxidative protein folding2019
- Author(s)
  Okumura M,* Noi K, Kanemura S, Kinoshita M, Saio T, Inoue Y, Hikima T, Akiyama S, Ogura T,* Inaba K.*
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Pages: 499-509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Protein Disulfide Isomerase family: from Proteostasis to Pathogenesis2019
- Author(s)
  Matsusaki M.#, Kanemura S.#, Kinoshita M.#, Lee Y.H., Inaba K.*, and Okumura M.* (#equal contribution *corresponding authors)
- Journal Title
  
  Biochim Biophys Acta-general subjects
  
  Volume: in press Issue: 2 Pages: 30080-30087
- DOI
  10.1016/j.bbagen.2019.04.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-19J00893
[Journal Article] Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-β (1-40).2019
- Author(s)
  Lin Y, Sahoo BR, Ozawa D, Kinoshita M, Kang J, Lim MH, Okumura M, Huh YH, Moon E, Jang JH, Lee HJ, Ryu KY, Ham S, Won HS, Ryu KS, Sugiki T, Bang JK, Hoe HS, Fujiwara T, Ramamoorthy A, Lee YH.*
- Journal Title
  
  ACS nano
  
  Volume: 13(8) Pages: 8766-8783
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Journal Article] Dynamic assembly of protein disulfide isomerase in catalysis of oxidative folding2019
- Author(s)
  Okumura Masaki、Noi Kentaro、Kanemura Shingo、Kinoshita Misaki、Saio Tomohide、Inoue Yuichi、Hikima Takaaki、Akiyama Shuji、Ogura Teru、Inaba Kenji
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 5 Pages: 499-509
- DOI
  10.1038/s41589-019-0268-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05657, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-19K06520, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-18H03978, KAKENHI-PLANNED-26116005, KAKENHI-PUBLICLY-17H05867, KAKENHI-PUBLICLY-19H04945
[Journal Article] Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-β (1-40)2019
- Author(s)
  Lin Y, Sahoo BR, Ozawa D, Kinoshita M, Kang J, Lim MH, Okumura M, Huh YH, Moon E, Jang JH, Lee HJ, Ryu KY, Ham S, Won HS, Ryu KS, Sugiki T, Bang JK, Hoe HS, Fujiwara T, Ramamoorthy A, Lee YH
- Journal Title
  
  ACS nano
  
  Volume: 27 Issue: 8 Pages: 8766-8783
- DOI
  10.1021/acsnano.9b01578
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Journal Article] Impact of membrane curvature on amyloid aggregation2018
- Author(s)
  Terakawa Mayu S.、Lin Yuxi、Kinoshita Misaki、Kanemura Shingo、Itoh Dai、Sugiki Toshihiko、Okumura Masaki、Ramamoorthy Ayyalusamy、Lee Young-Ho
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: － Issue: 9 Pages: 30130-30135
- DOI
  10.1016/j.bbamem.2018.04.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07362, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-17K15098
[Journal Article] Ero1-mediated reoxidation of PDI accelerates the folding of cone-snail toxins2018
- Author(s)
  O'Brien H., Kanemura S., Okumura M., Baskin P., Bandyopadhyay P., Ellgaard L., Inaba K., and Safavi-Hemami H.*
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 11 Issue: 11 Pages: 3418-3418
- DOI
  10.3390/ijms19113418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-17H06521, KAKENHI-PROJECT-17K15098, KAKENHI-PLANNED-26116005
[Journal Article] Energy landscape of polymorphic amyloid generation of β2-microglobulin revealed by calorimetry.2018
- Author(s)
  Kinoshita M., Lin Y., Itoh D., Okumura M., Markova N., Ladbury J.E., Sterpone F., and Lee Y.H.*
- Journal Title
  
  Chem Commun (Camb).
  
  Volume: 57 Issue: 57 Pages: 7995-7998
- DOI
  10.1039/c8cc02718h
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-17K07362, KAKENHI-PROJECT-17K15098
[Journal Article] The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation.2017
- Author(s)
  Maegawa KI, Watanabe S#, Noi K#, Okumura M#, Amagai Y#, Inoue M, Ushioda R, Nagata K, Ogura T, Inaba K.(#equal contribution)
- Journal Title
  
  Structure
  
  Volume: 25 Issue: 6 Pages: 846-857
- DOI
  10.1016/j.str.2017.04.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15098, KAKENHI-PUBLICLY-17H05675, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-15H04335, KAKENHI-PLANNED-26116005
[Journal Article] Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue2017
- Author(s)
  Kenta Arai+, Toshiki Takei+, Masaki Okumura+, Satoshi Watanabe+, Yuta Amagai, Yuya Asahina, Luis Moroder, Hironobu Hojo, Kenji Inaba, and Michio Iwaoka
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 印刷中 Issue: 20 Pages: 5522-5526
- DOI
  10.1002/anie.201701654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-17K05792, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-17K18123, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-15H04335, KAKENHI-PLANNED-26116005
[Journal Article] The highly dynamic nature of ERdj5 is key to efficient ERAD of aberrant protein oligomers2017
- Author(s)
  K. Maegawa, S. Watanabe#, K. Noi#, M. Okumura#, Y. Amagai#, M. Inoue, R. Ushioda, K. Nagata, T. Ogura, and K. Inaba*. (#These authors contributed equally to this work.)
- Journal Title
  
  Structure
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Journal Article] Preparation of Selenoinsulin as a Long-Lasting Insulin Analog2017
- Author(s)
  K. Arai#, T. Takei#, M. Okumura#, S. Watanabe#, Y. Amagai, Y. Asahina, H. Hojo*, K. Inaba*, M. Iwaoka*. (#These authors contributed equally to this work.)
- Journal Title
  
  Angewandte Chemie.,
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Journal Article] Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj52016
- Author(s)
  R. Ushioda, A. Miyamotod, M. Inoue, S. Watanabe, M. Okumurae, K. Maegawa, K. Uegaki, S. Fujii, Y. Fukuda, M. Umitsu, J. Takagi, K. Inaba, K. Mikoshibad, and K. Nagata
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 113(41) Issue: 41 Pages: 6055-6063
- DOI
  10.1073/pnas.1605818113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01545, KAKENHI-PUBLICLY-15H01626, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-24227009
[Journal Article] Human Ero1α undergoes dual regulation through complementary redox interactions with PDI2016
- Author(s)
  S. Kanemura, M. Okumura, K. Yutani, T. Ramming, T. Hikima, C. Appenzeller-Herzog, S. Akiyama and K. Inaba*.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 46 Pages: 23952-23964
- DOI
  10.1074/jbc.m116.735662
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626, KAKENHI-PROJECT-15J06349
[Journal Article] One-dimensional sliding of p53 along DNA is accelerated in the presence of Ca(2+) or Mg(2+) at millimolar concentrations2015
- Author(s)
  Murata A, Ito Y, Kashima R, Kanbayashi S, Nanatani K, Igarashi C, Okumura M, Inaba K, Tokino T, Takahashi S, Kamagata K
- Journal Title
  
  JOURNAL OF MOLECULAR BIOLOGY
  
  Volume: 427 Issue: 16 Pages: 2663-2678
- DOI
  10.1016/j.jmb.2015.06.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430115, KAKENHI-PUBLICLY-15H01626, KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-13J04030, KAKENHI-PROJECT-26650045, KAKENHI-PROJECT-26840045, KAKENHI-PROJECT-26282213, KAKENHI-PUBLICLY-15H01625, KAKENHI-PLANNED-26116005
[Journal Article] Structural Stability of Amyloid Fibrils Depends on the Existence of the Peripheral Sequence near the Core Cross-03B2 Region2015
- Author(s)
  M. Saiki, K. Shiba, and M. Okumura.
- Journal Title
  
  FEBS Lett.
  
  Volume: 589 Issue: 23 Pages: 3541-3547
- DOI
  10.1016/j.febslet.2015.10.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01626, KAKENHI-PROJECT-13J04030
[Journal Article] Structures and functions of protein disulfide isomerase family members involved in proteostasis in the endoplasmic reticulum.2015
- Author(s)
  Okumura M, Kadokura H, Inaba K.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 83 Pages: 314-322
- DOI
  10.1016/j.freeradbiomed.2015.02.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580141, KAKENHI-PROJECT-15K07381, KAKENHI-PUBLICLY-15H01626, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-13J04030, KAKENHI-PLANNED-26116005
[Journal Article] Cysteines 208 and 241 in Ero1 are required for maximal catalytic turnover2015
- Author(s)
  T. Ramming, S. Kanemura, M. Okumura, K. Inaba and C. Appenzeller-Herzog.
- Journal Title
  
  Redox Biology
  
  Volume: 7 Pages: 14-20
- DOI
  10.1016/j.redox.2015.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-15J06349, KAKENHI-PROJECT-13J04030, KAKENHI-PLANNED-26116005
[Journal Article] A PDI-catalyzed thiol/disulfide switch regulates the production of hydrogen peroxide by human Ero12015
- Author(s)
  T. Ramming, M. Okumura, S. Kanemura, S. Baday, J. Birk, S. Moes, P. Jenö, S. Bernèche, K. Inaba and C. Appenzeller-Herzog.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 83 Pages: 361-372
- DOI
  10.1016/j.freeradbiomed.2015.02.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-15J06349, KAKENHI-PROJECT-13J04030, KAKENHI-PLANNED-26116005
[Patent] タンパク質のフォールディング剤2021
- Inventor(s)
  奥村正樹, 村岡貴博, 岡田隼輔, 稲葉謙次, 松﨑元紀
- Industrial Property Rights Holder
  奥村正樹, 村岡貴博, 岡田隼輔, 稲葉謙次, 松﨑元紀
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Patent] 液滴及びその製造方法2020
- Inventor(s)
  奥村正樹、松﨑元紀、金村進吾、齋尾智英、稲葉謙次
- Industrial Property Rights Holder
  奥村正樹、松﨑元紀、金村進吾、齋尾智英、稲葉謙次
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K06520
[Patent] 液滴及びその製造方法2020
- Inventor(s)
  奥村正樹, 松﨑元紀, 金村進吾, 稲葉謙次, 齋尾智英
- Industrial Property Rights Holder
  奥村正樹, 松﨑元紀, 金村進吾, 稲葉謙次, 齋尾智英
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Patent] 液滴及びその製造方法2020
- Inventor(s)
  奥村正樹, 松﨑元紀, 金村進吾, 稲葉謙次, 齋尾智英
- Industrial Property Rights Holder
  奥村正樹, 松﨑元紀, 金村進吾, 稲葉謙次, 齋尾智英
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Patent] タンパク質のリフォールディング剤、タンパク質のリフォールディング方法及びタンパク質の再生方法2018
- Inventor(s)
  奥村正樹、村岡貴博、岡田隼輔、稲葉謙次、松﨑元紀
- Industrial Property Rights Holder
  奥村正樹、村岡貴博、岡田隼輔、稲葉謙次、松﨑元紀
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-109769
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K15098
[Patent] タンパク質のリフォールディング剤、タンパク質のリフォールディング方法及びタンパク質の再生方法2018
- Inventor(s)
  奥村正樹、村岡貴博、岡田隼輔、稲葉謙次、松﨑元紀
- Industrial Property Rights Holder
  奥村正樹、村岡貴博、岡田隼輔、稲葉謙次、松﨑元紀
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-109769
- Filing Date
  2018
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] 小胞体ストレスセンサーIRE1による活性酸素種の直接的感知と分子シャペロンによるその制御2024
- Author(s)
  松崎元紀、金村進吾、齋尾智英、稲葉謙次、奥村正樹
- Organizer
  日本農芸化学会2024度大会
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] フォールディングとアンフォールディングの自在操作の実現2024
- Author(s)
  奥村正樹
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 細胞における遅延制御反応場の形成機構と機能発現の探求2024
- Author(s)
  奥村正樹
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] フォールディングとアンフォールディングの自在操作の実現2024
- Author(s)
  奥村正樹
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 細胞における遅延制御反応場の形成機構と機能発現の探求2024
- Author(s)
  奥村正樹
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] フォールディングとアンフォールディングの自在操作の実現2024
- Author(s)
  奥村正樹
- Organizer
  日本化学会第104春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 小胞体局在因子による液滴の内部構造と機能の相関研究2024
- Author(s)
  奥村正樹
- Organizer
  大阪大学蛋白質研究所セミナー/第8回LLPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 小胞体局在因子による液滴の内部構造と機能の相関研究2024
- Author(s)
  奥村正樹
- Organizer
  大阪大学蛋白質研究所セミナー/第8回LLPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 小胞体内相分離の理解2023
- Author(s)
  奥村正樹
- Organizer
  第23回日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] Elucidating the enzymatic reductive unfolding mechanism of spike/envelope proteins to guide anti-virus activities2023
- Author(s)
  Shingo Kanemura, Rina Hashimoto, Motonori Matsusaki, Takuya Mabuchi, Mai Watabe, Tomohide Saio, Kazuo Takayama, Young-Ho Lee, Masaki Okumura
- Organizer
  第23回日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] Understanding the mechanism by which Protein Disulfide Isomerase (PDI) family guide proper oxidative folding2023
- Author(s)
  Masaki Okumura
- Organizer
  Zoominar "Amyloid Symposium"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 小胞体内相分離の理解2023
- Author(s)
  奥村正樹
- Organizer
  第23回日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 多量体分析で解き明かす小胞体ストレスセンサーが細胞応答を量的に調節する仕組み2023
- Author(s)
  松崎元紀、奥村正樹
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 小胞体内相分離の理解2023
- Author(s)
  奥村正樹
- Organizer
  第23回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] Understanding the mechanism by which Protein Disulfide Isomerase (PDI) family guide proper oxidative folding2023
- Author(s)
  Masaki Okumura
- Organizer
  Zoominar "Amyloid Symposium"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] フォールディングの酵素学的速度制御2023
- Author(s)
  奥村正樹
- Organizer
  第46回分子生物学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 基質触媒におけるPDI酵素群の動的会合体形成の理解2023
- Author(s)
  奥村正樹
- Organizer
  日本化学会第103春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 各生物学的階層におけるタンパク質品質管理の理解2023
- Author(s)
  奥村正樹
- Organizer
  神戸学院大学セミナー知の創造セミナー 4回目
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 小胞体ストレスセンサーIRE1 によるストレス感知と越膜シグナル変換の分子機構2023
- Author(s)
  松崎元紀、横山武司、次田篤史、金村進吾、田尻道子、明石知子、野井健太郎、齋尾智英、稲葉謙次、奥村正樹
- Organizer
  第96回日本生化学会
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] Elucidating the enzymatic reductive unfolding mechanism of spike/envelope proteins to guide anti-virus activities2023
- Author(s)
  Shingo Kanemura, Rina Hashimoto, Motonori Matsusaki, Takuya Mabuchi, Mai Watabe, Tomohide Saio, Kazuo Takayama, Young-Ho Lee, Masaki Okumura
- Organizer
  第23回日本蛋白質科学会年会　★若手賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 小胞体局在因子による液滴の内部構造と機能の相関研究2023
- Author(s)
  奥村正樹
- Organizer
  大阪大学蛋白質研究所セミナー/第8回LLPS研究会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] Discovery of a transient reaction field in the endoplasmic reticulum2023
- Author(s)
  Masaki Okumura
- Organizer
  International Cross-disciplinary Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] PDI familyによる小胞体内プロインスリンのフォールディング触媒機構の理解2023
- Author(s)
  倉持円来, 関凪沙, 荒井堅太, 山口宏, 稲葉謙次, 金村進吾, 奥村正樹
- Organizer
  第46回日本分子生物学会年会 ★サイエンスピッチ賞受賞
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] PDI familyによる小胞体内プロインスリンのフォールディング触媒機構の理解2023
- Author(s)
  倉持円来, 関凪沙, 荒井堅太, 山口宏, 稲葉謙次, 金村進吾, 奥村正樹
- Organizer
  第46回分子生物学会
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 小胞体ストレスセンサーIRE1の多量体形成ポテンシャルとストレス感知2023
- Author(s)
  松崎元紀、横山武司、次田篤史、金村進吾、田尻道子、明石知子、野井健太郎、齋尾智英、稲葉謙次、奥村正樹
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] Discovery of a transient reaction field in the endoplasmic reticulum2023
- Author(s)
  Masaki Okumura
- Organizer
  International Cross-disciplinary Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 各生物学的階層におけるタンパク質品質管理の理解2023
- Author(s)
  奥村正樹
- Organizer
  神戸学院大学セミナー知の創造セミナー 4回目
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] Discovery of a transient reaction field in the endoplasmic reticulum2023
- Author(s)
  Masaki Okumura
- Organizer
  International Cross-disciplinary Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] 基質触媒におけるPDI酵素群の動的会合体形成の理解2023
- Author(s)
  奥村正樹
- Organizer
  日本化学会第103春季年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] フォールディングの酵素学的速度制御2023
- Author(s)
  奥村正樹
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23KK0105
[Presentation] フォールディングの酵素学的速度制御2023
- Author(s)
  奥村正樹
- Organizer
  第46回分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 小胞体内における酸化的フォールディング触媒ネットワークの理解2022
- Author(s)
  奥村正樹
- Organizer
  第95回日本生化学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] ホログラフィック顕微鏡を用いた相分離観察例の紹介2022
- Author(s)
  奥村正樹
- Organizer
  第45回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] PDIファミリーのシャペロン機能の理解：プロテオスタスと神経変性疾患2022
- Author(s)
  奥村正樹
- Organizer
  第45回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] Protein Disulfide Isomerase family; their molecular actions and functions2022
- Author(s)
  Masaki Okumura
- Organizer
  Redox Week in Sendai 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 小胞体内における酸化的フォールディング触媒ネットワークの理解2022
- Author(s)
  奥村正樹
- Organizer
  第95回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] 各階層における酸化的フォールディング触媒システムの理解2022
- Author(s)
  奥村正樹
- Organizer
  第22回日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] ホログラフィック顕微鏡を用いた相分離観察例の紹介2022
- Author(s)
  奥村正樹
- Organizer
  第45回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] Understanding the proteostasis network in the endoplasmic reticulum2022
- Author(s)
  Masaki Okumura
- Organizer
  Korea-Japan Joint Workshop on Biofunctional Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーのシャペロン機能の理解：プロテオスタスと神経変性疾患2022
- Author(s)
  奥村正樹
- Organizer
  第45回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] Structural insights into the protein control system mechanism by PDI family, the endoplasmic reticulum-resident chaperone/enzyme2022
- Author(s)
  Masaki Okumura
- Organizer
  Protein Folding, Aggregation, Misfolding Disease, and Disease Crosstalk
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] Protein Disulfide Isomerase family; their molecular actions and functions2022
- Author(s)
  Masaki Okumura
- Organizer
  Redox Week in Sendai 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 各階層における酸化的フォールディング触媒システムの理解2022
- Author(s)
  奥村正樹
- Organizer
  第22回日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23472
[Presentation] Structural insights into the protein control system mechanism by PDI family, the endoplasmic reticulum-resident chaperone/enzyme2022
- Author(s)
  Masaki Okumura
- Organizer
  Protein Folding, Aggregation, Misfolding Disease, and Disease Crosstalk
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] Understanding the proteostasis network in the endoplasmic reticulum2022
- Author(s)
  Masaki Okumura
- Organizer
  Korea-Japan Joint Workshop on Biofunctional Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] プロテインジスルフィドイソメラーゼ群による基質触媒機構の解明2021
- Author(s)
  奥村正樹
- Organizer
  天野財団第22回酵素応用シンポジウム研究奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] プロテインジスルフィドイソメラーゼ群による基質触媒機構の解明2021
- Author(s)
  奥村正樹
- Organizer
  天野財団第22回酵素応用シンポジウム研究奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] PDI familyの動的な会合による小胞体内タンパク質品質管理の理解2021
- Author(s)
  奥村正樹
- Organizer
  分子生物学会 WS
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 小胞体内で液滴を形成する因子の生理学的機能の理解2021
- Author(s)
  奥村正樹
- Organizer
  第5回LLPS研究会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] 小胞体内酸化的フォールディングの触媒システムの理解2021
- Author(s)
  奥村正樹
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 小胞体内酸化的フォールディングの触媒システムの理解2021
- Author(s)
  奥村正樹
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05095
[Presentation] PDI familyの動的な会合による小胞体内タンパク質品質管理の理解2021
- Author(s)
  奥村正樹
- Organizer
  分子生物学会 WS
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 小胞体内で液滴を形成する因子の生理学的機能の理解2021
- Author(s)
  奥村正樹
- Organizer
  第5回LLPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 液液相分離する小胞体内シャペロンの発見、機能、制御機構2020
- Author(s)
  奥村正樹
- Organizer
  生化学会年会 web セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Presentation] 小胞体内ジスルフィド結合触媒ネットワークとインスリンフォールディングの品質管理2020
- Author(s)
  奥村正樹、稲葉謙次
- Organizer
  分子生物学会webフォーラム
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Direct observation of actions of Protein Disulfide Isomerase in the catalysis of oxidative folding2020
- Author(s)
  Masaki Okumura
- Organizer
  KBSI seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 液液相分離する小胞体内シャペロンの発見、機能、制御機構2020
- Author(s)
  奥村　正樹
- Organizer
  生化学会年会 web セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 液液相分離する小胞体内シャペロンの発見、機能、制御機構2020
- Author(s)
  奥村正樹
- Organizer
  生化学会年会 web セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 小胞体内ジスルフィド結合触媒ネットワークとインスリンフォールディングの品質管理2020
- Author(s)
  奥村正樹、稲葉謙次
- Organizer
  分子生物学会webフォーラム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04688
[Presentation] Direct observation of actions of Protein Disulfide Isomerase in the catalysis of oxidative folding2020
- Author(s)
  Masaki Okumura
- Organizer
  KBSI seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 小胞体内ジスルフィド結合触媒ネットワークとインスリンフォールディングの品質管理2020
- Author(s)
  奥村正樹、稲葉謙次
- Organizer
  分子生物学会webフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Understanding the mechanism by PDI family control proteostasis2019
- Author(s)
  奥村正樹、稲葉謙次
- Organizer
  第92回生化学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 小胞体内タンパク質の品質管理のフロンティア～温故知新～2019
- Author(s)
  奥村正樹
- Organizer
  関西学院大学理工学部講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during the catalysis of oxidative protein folding2019
- Author(s)
  Masaki Okumura, Kentaro Noi, Shingo Kanemura, Misaki Kinoshita, Tomohide Saio, Yuichi Inoue, Takaaki Hikima, Shuji Akiyama, Teru Ogura, Kenji Inaba
- Organizer
  14th ER redox club meeting, Herrsching am Ammersee, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーによるβ2-microglubulinの品質管理機構の解明2019
- Author(s)
  木下岬, 金村進吾, 松崎元紀, 李映昊, 稲葉謙次, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Structural insights into the protein homeostasis mechanism in the endoplasmic reticulum2019
- Author(s)
  Masaki Okumura
- Organizer
  International symposium on unfolded proteins, protein folding, and disease-causing aggregation, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 新規レドックス分子のデザイン法確立と酸化的フォールディングへの応用2019
- Author(s)
  松崎元紀, 岡田隼輔, 荒井堅太, 日高雄二, 稲葉謙次, 村岡貴博, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーのシャペロン機能の新展開2019
- Author(s)
  奥村正樹
- Organizer
  第3回タンパク質可塑性についての研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Newly developedthiol-disulfide exchange agent,guanidino-thiol2019
- Author(s)
  Motonori Matsusaki, Shunsuke Okada, Kenta Arai, Yuji Hidaka, Kenji Inaba, Takahiro Muraoka, Masaki Okumura
- Organizer
  14th ER redox club meeting, Herrsching am Ammersee, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Structural insights into the protein homeostasis mechanism in the endoplasmic reticulum2019
- Author(s)
  Masaki Okumura
- Organizer
  International symposium on unfolded proteins, protein folding, and disease-causing aggregation, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 新規レドックス分子による酸化的フォールディングの促進と応用2019
- Author(s)
  松崎元紀, 岡田隼輔, 荒井堅太, 日高雄二, 稲葉謙次, 村岡貴博, 奥村正樹
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 小胞体内のタンパク質品質管理機構の解明2019
- Author(s)
  奥村正樹
- Organizer
  次世代研究者シンポジウム2019、名古屋大学
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリーメンバーP5の新規構造と機能2019
- Author(s)
  奥村正樹, 金村進吾, 松崎元紀, 木下岬, 荒井堅太, 平山千尋, 天貝佑太, 門倉広, 秋山修志, 稲葉謙次
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーによるβ2-microglubulinの品質管理機構の解明2019
- Author(s)
  木下岬, 金村進吾, 松崎元紀, 李映昊, 稲葉謙次, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリーによる小胞体内品質管理機構の最前線2019
- Author(s)
  奥村正樹
- Organizer
  成蹊大学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーによる前駆体タンパク質フォールディング中間体の分子認識機構の解明2019
- Author(s)
  増田光紀, 金村進吾, 木下岬, 山口宏, 日高雄二, 稲葉謙次, 奥村正樹
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 酸化的フォールディングを触媒するPDIの可視化2019
- Author(s)
  奥村正樹, 野井健太郎, 金村進吾, 木下岬, 斉尾智英, 井上裕一, 引間孝明, 秋山修志, 小椋光, 稲葉謙次
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリーメンバーP5の新規構造と機能2019
- Author(s)
  奥村正樹, 金村進吾, 松崎元紀, 木下岬, 荒井堅太, 平山千尋, 天貝佑太, 門倉広, 秋山修志, 稲葉謙次
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリー酵素によるヒト由来ガレクチンの構造機能制御機構の解明2019
- Author(s)
  金村進吾, 黒井邦巧, 松崎元紀, 山口宏, 中林孝和, 稲葉謙次, 奥村正樹
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 「可塑性」の学際的接点2019
- Author(s)
  奥村正樹
- Organizer
  「可塑性」研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during the catalysis of oxidative protein folding2019
- Author(s)
  Masaki Okumura, Kentaro Noi, Shingo Kanemura, Misaki Kinoshita, Tomohide Saio, Yuichi Inoue, Takaaki Hikima, Shuji Akiyama, Teru Ogura, Kenji Inaba
- Organizer
  14th ER redox club meeting, Herrsching am Ammersee, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 小胞体内のタンパク質品質管理機構の解明2019
- Author(s)
  奥村正樹
- Organizer
  次世代研究者シンポジウム2019、名古屋大学
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 小胞体内タンパク質の品質管理のフロンティア～温故知新～2019
- Author(s)
  奥村正樹
- Organizer
  関西学院大学理工学部講演会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Understanding the proteostasis mechanism in the endoplasmic reticulum2019
- Author(s)
  M. Okumura
- Organizer
  358th IMEG Seminar, Kumamoto Univ.
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] Newly developedthiol-disulfide exchange agent,guanidino-thiol2019
- Author(s)
  Motonori Matsusaki, Shunsuke Okada, Kenta Arai, Yuji Hidaka, Kenji Inaba, Takahiro Muraoka, Masaki Okumura
- Organizer
  14th ER redox club meeting, Herrsching am Ammersee, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 「可塑性」の学際的接点2019
- Author(s)
  奥村正樹
- Organizer
  第1回タンパク質可塑性についての研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDI family酵素によるヒト由来ガレクチンの機能制御機構の解明2019
- Author(s)
  金村進吾, 黒井邦巧, 松崎元紀, 山口宏, 中林孝和, 稲葉謙次, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Understanding the mechanism by PDI family control proteostasis2019
- Author(s)
  奥村正樹、稲葉謙次
- Organizer
  第92回生化学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Coupling effects of thiol and urea-type groups for promotion of oxidative folding2019
- Author(s)
  Motonori Matsusaki, Shunsuke Okada, Kenji Inaba, Takahiro Muraoka, Masaki Okumura
- Organizer
  International symposium on unfolded proteins, protein folding, and disease-causing aggregation, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリーのシャペロン機能の新展開2019
- Author(s)
  奥村正樹
- Organizer
  第3回タンパク質可塑性についての研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Understanding the proteostasis mechanism in the endoplasmic reticulum2019
- Author(s)
  M. Okumura
- Organizer
  358th IMEG Seminar, Kumamoto Univ.
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] Structures and functions of PDI family members involved in proteostasis2019
- Author(s)
  Masaki Okumura
- Organizer
  University of Glasgow, UK
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDI family酵素によるヒト由来ガレクチンの機能制御機構の解明2019
- Author(s)
  金村進吾, 黒井邦巧, 松崎元紀, 山口宏, 中林孝和, 稲葉謙次, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリー酵素によるヒト由来ガレクチンの構造機能制御機構の解明2019
- Author(s)
  金村進吾, 黒井邦巧, 松崎元紀, 山口宏, 中林孝和, 稲葉謙次, 奥村正樹
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] 新規レドックス分子のデザイン法確立と酸化的フォールディングへの応用2019
- Author(s)
  松崎元紀, 岡田隼輔, 荒井堅太, 日高雄二, 稲葉謙次, 村岡貴博, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Coupling effects of thiol and urea-type groups for promotion of oxidative folding2019
- Author(s)
  Motonori Matsusaki, Shunsuke Okada, Kenji Inaba, Takahiro Muraoka, Masaki Okumura
- Organizer
  International symposium on unfolded proteins, protein folding, and disease-causing aggregation, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーが触媒する前駆体タンパク質の酸化的フォールディング機構の解明2019
- Author(s)
  増田光紀, 金村進吾, 木下岬, 山口宏, 日高雄二, 稲葉謙次, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] Structural insights into oxidative protein folding and chaperoning in the mammalian endoplasmic reticulum2019
- Author(s)
  奥村正樹
- Organizer
  第二回タンパク質可塑性の研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] Structures and functions of PDI family members involved in proteostasis2019
- Author(s)
  Masaki Okumura
- Organizer
  University of Glasgow, UK
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06520
[Presentation] PDIファミリーによる小胞体内品質管理機構の最前線2019
- Author(s)
  奥村正樹
- Organizer
  成蹊大学セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] PDIファミリーが触媒する前駆体タンパク質の酸化的フォールディング機構の解明2019
- Author(s)
  増田光紀, 金村進吾, 木下岬, 山口宏, 日高雄二, 稲葉謙次, 奥村正樹
- Organizer
  第92回生化学会年会
- Data Source
  KAKENHI-PUBLICLY-19H04799
[Presentation] 酵素の構造ダイナミクスから紐解く基質認識の理解―Protein Disulfide Isomeraseを事例として2018
- Author(s)
  奥村　正樹
- Organizer
  第18回日本蛋白質科学会年会、ランチョンセミナ-
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] 小胞体内局在酵素Protein Disulfide Isomerase familyによるタンパク質品質管理機構の理解2018
- Author(s)
  奥村　正樹
- Organizer
  北海道大学薬学部
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] 小胞体内局在酵素Protein Disulfide Isomerase familyによるタンパク質品質管理機構の理解2018
- Author(s)
  奥村　正樹
- Organizer
  北海道大学薬学部
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] Dynamic assembly and disassembly of Protein Disulfide Isomerase during guiding proper oxidative protein folding2018
- Author(s)
  Masaki Okumura, Kentaro Noi, Shingo Kanemura, Shuji Akiyama,Teu Ogura, and Kenji Inaba
- Organizer
  CLS, Tokyo Tech. International Forum 2018　Redox regulation of protein functions,transcription, translation and folding
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] Understanding the proteotasis mechanism in the Endoplasmic Reticulum2018
- Author(s)
  M. Okumura
- Organizer
  KBSI seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] Dynamic assembly and disassembly of protein disulfide isomerase in catalysis of oxidative protein folding2018
- Author(s)
  M. Okumura
- Organizer
  333th IMEG Seminar, Kumamoto Univ.
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] 酵素の構造ダイナミクスから紐解く基質認識の理解―Protein Disulfide Isomeraseを事例として2018
- Author(s)
  奥村　正樹
- Organizer
  第18回日本蛋白質科学会年会、ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] Understanding the proteotasis mechanism in the Endoplasmic Reticulum2018
- Author(s)
  M. Okumura
- Organizer
  KBSI seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] Dynamic assembly and disassembly of protein disulfide isomerase in catalysis of oxidative protein folding2018
- Author(s)
  M. Okumura
- Organizer
  333th IMEG Seminar, Kumamoto Univ.
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] How do PDI family member proteins act on nascent chains to catalyze their oxidative protein folding?2017
- Author(s)
  奥村正樹、平山千尋、野井　健太郎、町田　幸大、今高　寛晃、小椋　光、稲葉　謙次
- Organizer
  第17回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] 高速原子間力顕微鏡が明らかにした基質に働きかけるProtein Disulfide Isomerase酵素の1分子動態2017
- Author(s)
  奥村正樹
- Organizer
  最先端光計測とライフサイエンスの近未来－Bio. Phys. Chem.三重点の探索－
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] How do PDI family member proteins act on nascent chains to catalyze their oxidative protein folding?2017
- Author(s)
  奥村正樹、平山千尋、野井　健太郎、町田　幸大、今高　寛晃、小椋　光、稲葉　謙次
- Organizer
  第17回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] Dynamic assembly and disassembly of Protein Disulfide Isomerase during guiding proper oxidative protein folding2017
- Author(s)
  Masaki Okumura, Kentaro Noi, Shingo Kanemura, Shuji Akiyama,Teu Ogura, and Kenji Inaba
- Organizer
  CLS, Tokyo Tech. International Forum 2018　Redox regulation of protein functions,transcription, translation and folding
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during the catalysis of oxidative protein folding2017
- Author(s)
  奥村正樹、野井　健太郎、金村　進吾、引間　孝明、秋山　修志、小椋　光、稲葉　謙次
- Organizer
  第17回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05868
[Presentation] 高速AFMが明らかにしたPDI酵素による基質の酸化的フォールディング触媒機構の解明2017
- Author(s)
  奥村　正樹
- Organizer
  熊本大学発生研セミナー
- Place of Presentation
  熊本大学発生医学研究所(熊本県、熊本市)
- Year and Date
  2017-01-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during guiding oxidative protein folding2017
- Author(s)
  M. Okumura, K. Noi, S. Kanemura, S. Masui, T. Hikima, S. Akiyama, T. Ogura, and K. Inaba.
- Organizer
  Grand Challenges in Small-angle Scattering
- Place of Presentation
  岡崎カンファレンスセンター(愛知県、岡崎市)
- Year and Date
  2017-03-18
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during the catalysis of oxidative protein folding2017
- Author(s)
  奥村正樹、野井　健太郎、金村　進吾、引間　孝明、秋山　修志、小椋　光、稲葉　謙次
- Organizer
  第17回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15098
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during the catalysis of oxidative protein folding.2016
- Author(s)
  M. Okumura, K. Noi, S. Kanemura, T. Hikima, S. Akiyama, T. Ogura, K. Inaba.
- Organizer
  Nascent Chain Biology 2016
- Place of Presentation
  富士レークホテル(山梨県、南都留郡)
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Dynamic assembly/disassembly of Protein Disulfide Isomerase during the catalysis of oxidative protein folding.2016
- Author(s)
  M. Okumura, K. Noi, S. Kanemura, S. Masui, T. Hikima, S. Akiyama, T. Ogura, and K. Inaba.
- Organizer
  EMBO Meeting
- Place of Presentation
  Girona, Spain
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] 酸化的フォールディングを支える PDI ファミリー酵素の新規触媒機構の解明2016
- Author(s)
  奥村　正樹
- Organizer
  蛋白質科学会若手奨励賞受賞講演
- Place of Presentation
  福岡国際会議場(福岡県、福岡市)
- Year and Date
  2016-06-08
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Dual regulation of human Ero1 via redox interplays with PDI.2016
- Author(s)
  S. Kanemura, M. Okumura, K. Yutani, T. Ramming, C. Appenzeller-Herzog, S. Akiyama, K. Inaba.
- Organizer
  EMBO Meeting
- Place of Presentation
  Girona, Spain
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Human Ero1 undergoes dual regulation via redox interplays with PDI.2016
- Author(s)
  S. Kanemura, M. Okumura, K. Yutani, T. Ramming, C. Appenzeller-Herzog, S. Akiyama, K. Inaba.
- Organizer
  Nascent Chain Biology 2016
- Place of Presentation
  富士レークホテル(山梨県、南都留郡)
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Real-time monitoring of PDI-catalyzed oxidative protein folding by high-speed atomic force microscopy2015
- Author(s)
  奥村正樹
- Organizer
  第53回　生物物理学会年会
- Place of Presentation
  金沢大学(金沢市)
- Year and Date
  2015-09-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] Real-time monitoring of PDI-catalyzed oxidative protein folding by high-speed atomic force microscopy.2015
- Author(s)
  M. Okumura, K. Noi, S. Kanemura, S. Masui, T. Hikima, S. Akiyama, T. Ogura, and K. Inaba.
- Organizer
  ER&Redox Club Meeting
- Place of Presentation
  Venice, Italy.
- Year and Date
  2015-04-14
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] 高速AFMが明らかにしたPDIによる基質の酸化的フォールディング触媒機構の解明2015
- Author(s)
  奥村正樹、野井　健太郎、金村　進吾、秋山　修志、小椋　光、稲葉　謙次
- Organizer
  第38回　分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] 小胞体におけるタンパク質の品質管理2015
- Author(s)
  奥村正樹
- Organizer
  東海大学
- Place of Presentation
  東海大学湘南キャンパス(平塚市)
- Year and Date
  2015-11-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01626
[Presentation] 小胞体におけるタンパク質の品質管理；酵素による基質触媒反応を活写する2015
- Author(s)
  奥村正樹
- Organizer
  関西学院大学、理工学部講演会
- Place of Presentation
  関西学院大学(三田市)
- Year and Date
  2015-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01626
[]
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1. SAIO Tomohide (80740802)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Muraoka Takahiro (70509132)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 金村進吾 (50803178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 横山武司 (20719447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 松崎元紀 (90817040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. Inaba Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. SATO Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 時野隆至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 李映昊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 潮田亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 日高雄二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 荒井堅太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 門倉広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 北條裕信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okumura Masaki 奥村 正樹

OKUMURA MASAKI 奥村 正樹

Research Projects

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Co-Researchers

小胞体内の相分離区画を摂動する酸化還元の理解と化学制御Principal Investigator

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分泌経路におけるメゾスケール構造体プロファイリングの開拓Principal Investigator

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小胞体内液液相分離の作用機序解明と化学的制御Principal Investigator

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Organization of kinetics-driven supramolecular chemistry

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Elucidation of the mechanism of kinetically controlled reaction fields in cellsPrincipal Investigator

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Structural basis for recognition and regulation of protein folding intermediate by molecular chaperones in the endoplasmic reticulum

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分子夾雑環境における酸化的フォールディングのモニタリング法の開発Principal Investigator

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Understanding the protein homeostasis mechanism by P5, a member of the PDI familyPrincipal Investigator

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小胞体内MHCの立体構造構築の理解Principal Investigator

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Understanding the folding intermediate recognition mechanism by PDIPrincipal Investigator

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酵素基質相互作用を決定する動的構造制御Principal Investigator

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分子認識による酸化的フォールディングの1分子観察Principal Investigator

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[Book] 月刊細胞 特集「LC（Low-Complexity）ドメインの生物学」2024

Author(s)

Total Pages

Okumura Masaki 奥村正樹

OKUMURA MASAKI 奥村正樹

[Book] 月刊細胞特集「LC（Low-Complexity）ドメインの生物学」2024

[Book] 月刊細胞特集「LC（Low-Complexity）ドメインの生物学」2024

[Book] 月刊細胞特集「LC（Low-Complexity）ドメインの生物学」2024