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KOHDA Kouhuku  幸田 光復

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… Alternative Names

幸田 光復  コウダ コウフク

KOHDA Kohfuku  幸田 光復

幸山 光復

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Researcher Number 60124286
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2005: Musashino University, Faculty of Pharmacy, Professor, 薬学部, 教授
2002 – 2003: 名古屋市立大学, 大学院・薬学研究科, 助教授
1986 – 1999: 名古屋市立大学, 薬学部, 助教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy
Except Principal Investigator
Chemical pharmacy / 医薬分子機能学
Keywords
Principal Investigator
benzimidazole / 求電子的アミノ化 / DNA付加体 / 化学発癌 / アミノ化 / グアニン / デオキシグアノシン / DNA adduct / chemical carcinogenesis / 酸化 … More / electrophilic amination / N-アミノグアニン / Guanine / Guanosine / Deoxyguanosine / Amination / アリールヒドロキシルアミン / Nーアミノグアニン / グアノシン / arylamination / deoxyguanosine / arylamine / oxidation / DNA damage / 発癌機構 / DNA-付加体 / アリールアミノ化 / ベンツイミダゾール / アリールアミン / oridation / imidazole moiety / purine base / 発癌剤付加体 / 球電子的アミノ化 / イミダゾール部位 / プリン塩基 / N-amino-l-methylbenzimidazole / N-aminoguanine / l-methylbenzimidazole / q-ethylguanine / carcinogenesis / amination / guanine / N-アミノ-1-メチルベンツイミダゾール / 1-メチルベンツイミダゾール / 9-エチルグアニン / 8ーヒドロキシグアニン / serylーAMP / 4HAQO / 4NQO / 発癌 / DNA修飾 / 核酸塩基 / シスプラチン-グアニン復合体 / 脱アルキル化 / DNA修復 / 0^6-メチルグアニン-DNAメチルトランスフェレース / 0^6-ベンジルグアニン / 0^6-メチルグアニン / 核酸 … More
Except Principal Investigator
トポスチン / 合成 / 変異原性 / 遺伝毒性 / 代謝 / キノリン / 制がん薬 / リグニン / 細胞毒性 / ダイデムニンB / Quinolines / Microsomal enzyme / Metabolic activation / Fluorine derivative / Genotoxicity / Carcinogenicity / Heteroaromatics / Metabolism / 芳香族アミン / アミノキノリン / フッ素置換 / キノリン誘導体 / ミクロゾ-ム酵素 / 発癌活性化 / フッ素置換体 / 発癌性 / 含窒素複素環化合物 / AIDS / carcinogenicity / genotoxicity / mutagenicity / metabolism / lignin / nitrogen-containing aromatics / quinoline / エイズ / 発癌 / 含窒素芳香族化合物 / tocopherol / edaravone / catechin / fullerene / pharmacophore / active oxygen species / radical scavenger / oxyl radical / 神経毒性 / スピントラップ剤 / ESR / オキシラジカル / トコフェロール / エダラボン / カテキン / フラーレン / ファーマコフォア / 活性酸素種 / ラジカル消去剤 / オキシルラジカル / 遺伝子クローニング / エンドヌクレアーゼ / 除去修復 / 発がん / 修復酵素 / DNA修復 / DNA損傷 / アルキル化剤 / DNAトポイソメラーゼI阻害 / DNAトポイソメラーゼI / 酵素阻害 / トポイソメラーゼI / ティリバリン / スクリーニング法 / 静止期細胞 / 培養細胞 / 固型癌 / 制癌剤 / 免疫賦活 / 抗菌性 / 抗ウイルス性 / 合成リグニン / 木質化天然物 / トリフルオロ酢酸 / ジエチルリン酸シアニド / 立体選択的合成 / 海洋産ペプチド / ドラスタチン10 / ユリチアサイクラマイド / 立体配座 / 毒性発現機構 / 構造活性相関 / 制癌活性 / 海洋産環状ペプチド Less
  • Research Projects

    (19 results)
  • Co-Researchers

    (19 People)
  •  Development of novel oxyl-radical quenching pharmacophores as drug candidates

    • Principal Investigator
      MIYATA Naoki
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Nagoya City University
  •  DNAトポイソメラーゼI阻害活性を指標とする新規制がん薬の分子設計

    • Principal Investigator
      塩入 孝之
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya City University
  •  Chemical characteristics of the imidazole moiety of deoxyguanosinePrincipal Investigator

    • Principal Investigator
      KOHDA Kohfuku
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  天然有機化合物をリ-ド化合物とする制がん薬の分子設計

    • Principal Investigator
      塩入 孝之
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  天然有機化合物をリ-ド化合物とする制がん薬の分子設計

    • Principal Investigator
      塩入 孝之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  Amination of the imidazole moiety of guanine and the properties of the N-aminated imidazoles. Molecular mechanisms of induction of DNA damage.Principal Investigator

    • Principal Investigator
      KOHDA Kohfuku
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  新しい視点からの一次スクリーニング法の確立を目指して

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  Reactivity of imidazole moiety of fused aromatic ring for ionic and radical reaction species : Molecular stady for DNA damagePrincipal Investigator

    • Principal Investigator
      KOHDA Kohfuku
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  修復酵素メチルトランスフェレースの強力な阻害剤の開発:メチル化抗癌剤の作用増強Principal Investigator

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  核酸塩基の求電子的アミノ化反応:N-アミノ体を中間体とする新規修飾塩基類の合成Principal Investigator

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  核酸塩基の求電子的アミノ化反応ーN.アミノ体を中間体とする新規修飾塩基類の合成Principal Investigator

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  細胞毒性を有する海洋産環状ペプチドの合成と制癌への応用

    • Principal Investigator
      塩入 孝之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  医薬品資源としての木質素材:リグニン分画の抗ウイルス活性と免疫賦活化能

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  生物活性を有する海洋産環状ペプチドの合成と制癌への応用

    • Principal Investigator
      塩入 孝之
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  Metabolism of N-Containing Polycyclic Aromatic Hydrocarbons

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  Deprivation of Genotoxicity of N-Containing Heteroaromatics: Effect of Fluorine Substitution

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  4NQO処理細胞DNAにおける8ーヒドロキシグアニン残基の生成機構Principal Investigator

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  Amination of nucleic acid bases-A basic study on the reaction mechanism of aminating carcinogensPrincipal Investigator

    • Principal Investigator
      KOHDA Kohfuku
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  アルキル化剤によるがん原性DNA変異の生起とその抑制機構

    • Principal Investigator
      関口 睦夫
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  • 1.  KAWAZOE Yutaka (80106252)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  KAIYA Toyo (10080201)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  塩入 孝之 (20012627)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  浜田 康正 (90117846)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TAKAHASHI Kazuhiko (40117833)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MIYATA Naoki (50114674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  NAKAGAWA Hidehiko (80281674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Takayoshi (90372838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  関口 睦夫 (00037342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  石田 良司 (50150214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  藤堂 剛 (90163948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大塚 栄子 (80028836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  池永 満生 (70025378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  多田 万里子 (90073113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  GORROD John
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YAGI Haruhiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  JERINA Donald
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NONOYJAMA Me
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  NONOYAMA Meihan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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