IMAIZUMI Tsutomu 今泉勉

… Alternative Names

今泉勉イマイズミツトム

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Researcher Number	60148947
External Links
Affiliation (based on the past Project Information) *help	2009 – 2011: Kurume University, 医学部, 教授 2002 – 2005: 久留米大学, 医学部, 教授 1999 – 2000: 久留米大学, 医学部, 教授 1996 – 1997: 久留米大学, 医学部, 教授 1994: KURUME UNIVERSITY,MEDICINE,PROFESSOR & CHAIRMAN, 医学部, 教授 … More 1991 – 1993: 九州大学, 医学部, 講師 1988 – 1989: Kyushu University, Faculty of Medicine, Assistant Professor, 医学部, 講師 1986 – 1987: Kyushu University, Faculty of Medicine, Assistant, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine
Keywords	Principal Investigator ラット / 高血圧 / Hypertension / Vasodilation / Insulin / 一酸化窒素 / 細胞移植 / 遺伝子治療 / 家兎 / 交感神経活動 … More / 循環調節 / rabbits / vagus / aortic baroreceptors / aortic diameter / aortic depressor nerve / renal sympathetic nerve / atrial natriuretic peptide / 腎機能 / 迷走神経 / 大動脈径 / 動脈圧受容体 / 大動脈減圧神経 / 腎交感神経 / 心房性利尿ホルモン / macrophages / cell transplantation / stem cel / gene therapy / prostacyclin / pulmonary hypertension / レトロウイルスベクター / STAT3 / レトロウイルス / 肺高血圧 / シクロオキシゲナーゼ合成酵素 / プロスタグランジン合成酵素 / モノクロタリン / 肺高血圧症 / 遺伝子導入 / blood pressure variability, / sympathetic nervous system / brain / hypertension / nitricoxide / L-NMMA / NO / 中枢 / テレメトリー / 血圧変動 / 交感神経 / 脳 / Syndromex / 脳室内投与 / インシュリン / syndromex / ADMA / Asymmetric Dimethylarginine / 腎不全 / 血管内皮 / サイトカイン / アンジオテニシンII / 高脂血症 / がん / 遺伝子発現 / 再生医学 / 血管新生 / リモデリング / TNF-α / 心臓移植 / 移植後冠動脈硬化 / 中枢神経系 / レニン-アンジオテンシン系 / 心不全 / 周波数解析 / フ-リエ変換 / ホワイトノイズ法 / 心レセプタ- / 神経反射 / 心筋梗塞 / 心筋虚血 … More Except Principal Investigator 心不全 / STAT3 / SOCS / MCP-1 / sympathetic nerve activity / muscimol / GABA / 高血圧 / 動脈硬化 / serotonin / substance P / 血管形成 / 内皮前駆細胞 / 血管新生 / 血管内皮 / forearm blood flow / aortic depressor nerve / baroreceptors / ANP / 側枢室内投与 / 大動脈径 / 動脈圧受容器 / 反射性交感神経活動調節 / 心房性ナトリウム利尿ペプチド(ANP) / 前腕血流量 / 大動脈減圧神経 / 腎交感神経 / 圧受容器反射 / 心房性Na利尿ペプチド / Atrial natriuretic peptide / Spontaneously hypertensive rat / High salt intake / Cardiopulmonary baroreflex / 心房筋伸展 / 心房性ナトリウム利尿ペブチド / 高血圧自然発生ラット / 高食塩食摂取 / 心肺圧受容体 / Interleukin-6 / macrophage / atherosclerosis / マクロファージ泡沫化 / 酸化LDL / SOCS3 / STAT / JAK / サイトカイン / インターロイキン6 / マクロファージ / Gene of 7ND / OLETF Rat / Cardiac Fibrosis / Cardiac Remodeling / Heart Failure / TGF-β / 酸化ストレス / 炎症細胞浸潤 / 心・血管リモデリング / 左室拡張不全 / 7ND遺伝子 / OLETFラット / 心筋線維化 / 心リモデリング / 生活習慣病 / macrophages / hypertrophy / hypertension / myocardial fibrosis / blood pressure variability / 拡張能障害 / アンジオテニシンII / 接着因子 / リモデリング / 拡張障害 / アンジオテンシンII / ケモカイン / 線維化 / 炎症 / 血圧変動 / shaker stress / NaCl / borderline hypertensive rat / 脳室内投与 / ビククリン / ムシモ-ル / ストレス / 境界型高血圧 / 食塩 / 交感神経活動 / 振盪ストレス刺激 / 食塩負荷 / 境界型高血圧ラット / dysfunction / endothelium-derived relaxing factor / coronary artery spasm / 血管内皮細胞依存性弛緩 / Ca^<2+>チャネル / Ca^<2+>ーカイネティックス / 心筋虚血 / 冠動脈攣縮 / サブスタンスP / セロトニン / 内皮細胞依存性血管弛緩因子 / 冠攣縮 / substaucep / endothelium / coronary spasm / EDRF / endo the lium / couonay spasm / カプトリル / handgrip運動 / 骨格筋栄養血流量 / 側副血管 / 血管内皮細胞 / 慢性閉塞性動脈硬化症 / 血管再生 / 虚血性心疾患 / 自己移植 / CD34陽性細胞 / 内皮細胞 / 骨髄細胞 / 虚血骨格筋 / 心機能 / 心臓発生 / FGF受容体 / 細胞タカルシウム濃度 / レトロウイルス / 細胞増殖因子 / 心筋細胞 / L-NMMA / L-NAME / 冠動脈 / ブタ / 内皮由来血管弛緩物質 / nitric oxide / メチレンブルー / ヘモグロビン / NMMA / スライス標本 / L-arginine / nitnic oxide / サブスタンス-P / L-アルジニン / No / Lーarginine / アセチルコリン / 前椀血流量 / 内非依存性血管拡張 Less

Mechanism of Endothelial Dysfunction in Chronic Kidney DiseasePrincipal Investigator
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Analysis of the role of signaling suppressor SOCS3 in the development of atherosclerosis
- Principal Investigator
  
  YASUKAWA Hideo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
骨髄単核細胞移植療法による虚血肢の遺伝子発現変化の網羅的解析と遺伝子治療への応用Principal Investigator
- Principal Investigator
  
  今泉勉
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
EFFECTS OF EXAGGERATED BLOOD PRESSURE VARIABILITY ON CARDIAC REMODELING AND PERIVASCULAR INFLAMMATION
- Principal Investigator
  
  KAI Hisashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
A possible treatment strategy for cardiovascular remodeling by metabolic syndrome-The gene therapy for use of MCP-1 7ND mutated gene-
- Principal Investigator
  
  KUWAHARA Fumitaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
NEW TREATMENT FOR PULMONAY HYPERTENSIONPrincipal Investigator
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
コロニー刺激因子を用いた新しい虚血部血管新生療法の開発-内皮前駆細胞動員療法-
- Principal Investigator
  
  室原豊明
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kurume University
移植後冠動脈硬化に対する抗炎症性サイトカイン療法の試みPrincipal Investigator
- Principal Investigator
  
  今泉勉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
自己骨髄単核細胞移植による心筋梗塞後血管新生療法の実験的試み
- Principal Investigator
  
  MUROHARA Toyoaki
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kurume University
Role of brain nitric oxide in the development of experimental hypertension.Principal Investigator
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University School of Medicine
心不全における内皮依存性血管拡張能異常に関する研究
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
心臓発生過程および成熟心臓機能における線維芽細胞成長因子の役割の解明
- Principal Investigator
  
  上野光
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Effects of Insulin on sympethetic tonePrincipal Investigator
- Principal Investigator
  
  IMAIZUMI Tsutomu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KURUME UNIVERSITY
  Kyushu University
心不全における内皮依存性血勘拡張能異常に関する研究
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
孤束核ニューロンのシナプス伝達における酸化窒素の役割に関する研究:特に逆行性精報伝達物質としての可能性について
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
心不全における内皮依存性血管拡張能異常に関する研究
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
心不全における交感神経緊張にアンジオテンシンが如何に関与するかについての研究Principal Investigator
- Principal Investigator
  
  今泉勉
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Role of central GABA system in hypertension induced by high salt and stress.
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Cellular and Molecular Mechanism Coronary Spasm
- Principal Investigator
  
  KOYANAGI Samon, 丸岡雄二
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心筋虚血時の反射性循環調節異常に関する検討Principal Investigator
- Principal Investigator
  
  今泉勉
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
心不全における運動時の骨格筋栄養血流量調節に関する研究
- Principal Investigator
  
  竹下彰
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
The role of atrial natriuretic peptide in control of circulation and body fluid in heart failure
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Effects of atrial natriuretic peptide on renal nerve activityPrincipal Investigator
- Principal Investigator
  
  TSUTOMU IMAIZUMI
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Factors contributing to increases in circulating hypertensive peptides in genetic hypertension
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University

All 2012 2011 2010 2009 2004 2003 Other

All Journal Article Presentation

[Journal Article] Cardiac-specific deletion of SOCS-3 prevents development of left ventricular remodeling after acute myocardial infarction2012
- Author(s)
  Oba T, Imaizumi T(他14人16番目)
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 59 Issue: 9 Pages: 838-852
- DOI
  10.1016/j.jacc.2011.10.887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-23659104, KAKENHI-PROJECT-23792094
[Journal Article] Inhibition of eNOS Phosphorylation Mediates Endothelial Dysfunction in Renal Failure : New Effect of Asymmetric Dimethylarginine2012
- Author(s)
  Kajimoto H, Kai H, Imaizumi T(他6人9番目)
- Journal Title
  
  Kidney International
  
  Volume: 81 Issue: 8 Pages: 762-768
- DOI
  10.1038/ki.2011.476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22590903, KAKENHI-PROJECT-22791042, KAKENHI-PROJECT-23591210, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24659640
[Journal Article] Low DBP may not be an independent risk for cardiovascular death in revascularized coronary artery disease patients2011
- Author(s)
  Kai H, Imaizumi T(他5人7番目)
- Journal Title
  
  J Hypertens
  
  Volume: 29 Issue: 10 Pages: 1889-1896
- DOI
  10.1097/hjh.0b013e32834a5a67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Longest survivor of pulmonary atresia with ventricular septal defect-well-developed major aortopulmonary collateral arteries demonstrated by multidetector computed tomography2011
- Author(s)
  Fukui D, Kai H, Imaizumi T(他9人12番目)
- Journal Title
  
  Circulation
  
  Volume: 124 Pages: 2155-2157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Augmented neovascularization with magnetized endothelial progenitor cells in rats with hind-limb ischemia2011
- Author(s)
  Koiwaya H, Imaizumi T(他7人9番目)
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 51 Issue: 1 Pages: 33-40
- DOI
  10.1016/j.yjmcc.2011.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats : a possible mechanism of diastolic dysfunction in postmenopausal women2011
- Author(s)
  Mori T, Kai H, Imaizumi T(他7人10番目)
- Journal Title
  
  Hypertens Res
  
  Volume: 34 Issue: 4 Pages: 496-502
- DOI
  10.1038/hr.2010.261
- NAID
  10031163207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-21590943, KAKENHI-PROJECT-22590565
[Journal Article] Serum level of pigment epithelium-derived factor is a marker of atherosclerosis in humans2011
- Author(s)
  Tahara N, Imaizumi T(他8人10番目)
- Journal Title
  
  Atherosclerosis
  
  Volume: 219 Pages: 311-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Plasma aldosterone levels and development of insulin resistance : prospective study in a general population2011
- Author(s)
  Kumagai E, Imaizumi T(他15人17番目)
- Journal Title
  
  Hypertension
  
  Volume: 58 Issue: 6 Pages: 1043-1048
- DOI
  10.1161/hypertensionaha.111.180521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-23790713, KAKENHI-PROJECT-23790714
[Journal Article] Administration of pigment epithelium-derived factor inhibits left ventricular remodeling and improves cardiac function in rats with acute myocardial infarction2011
- Author(s)
  Ueda S-I, Imaizumi T(他3人5番目)
- Journal Title
  
  Am J Pathol
  
  Volume: 178 Issue: 2 Pages: 591-598
- DOI
  10.1016/j.ajpath.2010.10.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways2011
- Author(s)
  Takayama N, Kai H, Imaizumi T(他7人10番目)
- Journal Title
  
  Hypertens Res
  
  Volume: 34 Issue: 3 Pages: 341-347
- DOI
  10.1038/hr.2010.229
- NAID
  10031163179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249, KAKENHI-PROJECT-21590943, KAKENHI-PROJECT-22590565, KAKENHI-PROJECT-22791042
[Journal Article] Target blood pressure for treatment of isolated systolic hypertension in the elderly : Valsartan in elderly isolated systolic hypertension study2010
- Author(s)
  Ogihara T, Imaizumi T(他12人12番目)
- Journal Title
  
  Hypertension
  
  Volume: 56 Issue: 2 Pages: 196-202
- DOI
  10.1161/hypertensionaha.109.146035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Autologous transplantation of bone marrow mononuclear cells improved ischemic peripheral neuropathy in humans2010
- Author(s)
  Arima K, Kai H, Imaizumi T(他8人11番目)
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 56 Issue: 3 Pages: 238-239
- DOI
  10.1016/j.jacc.2010.02.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats2010
- Author(s)
  Takemiya K, Kai H, Imaizumi T(他3人6番目)
- Journal Title
  
  Basic Res Cardiol
  
  Volume: 105 Issue: 3 Pages: 409-417
- DOI
  10.1007/s00395-009-0065-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation2009
- Author(s)
  Kudo H, Kai H, Imaizumi T(他10人13番目)
- Journal Title
  
  Hypertension
  
  Volume: 54 Issue: 4 Pages: 832-838
- DOI
  10.1161/hypertensionaha.109.135905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] 慢性腎不全患者の心血管病変進展における内因性NO合成阻害物質(ADMA)の役割2009
- Author(s)
  梶本英美、甲斐久史、今泉勉
- Journal Title
  
  腎臓
  
  Volume: 32 Pages: 103-107
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Higher heart rate may predispose to obesity and diabetes mellitus : 20-year prospective study in a general population2009
- Author(s)
  Shigetoh Y, Imaizumi T(他8人10番目)
- Journal Title
  
  Am J Hypertens
  
  Volume: 22 Issue: 2 Pages: 151-155
- DOI
  10.1038/ajh.2008.331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] 慢性腎不全患者の心血管病変進展における内因性NO 合成阻害物質(ADMA)の役割2009
- Author(s)
  梶本英美、甲斐久史、今泉勉
- Journal Title
  
  腎臓 32
  
  Pages: 103-107
- Data Source
  KAKENHI-PROJECT-21390249
[Journal Article] Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouse.2004
- Author(s)
  Shimada T, Takeshita Y, Murohara T, Sasaki K, Egami K, Shintani S, Katsuda Y, Ikeda H, Nabeshima Y, Imaizumi T
- Journal Title
  
  Criculation 110
  
  Pages: 1148-1155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Advanced glycation end products activate mesangial TGF-β-Smad signaling via angiotensin II-type I receptor interaction.2004
- Author(s)
  Fukami K, Ueda S, Yamagishi S, Kato S, Inagaki Y, Takeuchi M, Motoyama Y, Bucala R, Iida S, Tamaki K, Imaizumi T, Cooper EM, Okuda S
- Journal Title
  
  Kidny Int 66
  
  Pages: 2137-2147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscle attenuates monocrotaline -induced pulmonary hypertension and prolongs survival in rats.2004
- Author(s)
  Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okumura K, Imaizumi T
- Journal Title
  
  Human Gene Ther 15
  
  Pages: 1270-1278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.2004
- Author(s)
  Tokuda K, Kai H, Kuwahara F, Yasukawa H, Tahara N, Kudo H, Takemiya K, Koga M, Yamamoto T, Imaizumi T.
- Journal Title
  
  Hypertension 43(2 pt2)
  
  Pages: 499-503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590781
[Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004
- Author(s)
  Tahara N, Kai H, Niiyama H, Mori T, Sugi Y, Takayama N, Yasukawa H, Numaguchi Y, Matsui H, Okamura K, Imaizumi T.
- Journal Title
  
  Human Gene Ther 15(12)
  
  Pages: 1270-1278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Repeated gene transfers of naked prostacyclin synthase plasmid into skeletal muscles attenuate monocrotaline-induced pulmonary hypertension and prolong survival in rats.2004
- Author(s)
  Tahara N, Imaizumi T(全11名11番目)
- Journal Title
  
  Human Gene Ther 15(12)
  
  Pages: 1270-1278
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction-Another model of inflammation-2004
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T.
- Journal Title
  
  Hypertension 43(4)
  
  Pages: 739-745
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Angiogenesis and vasculogenesis are impaired in precocious aging klotho mouse2004
- Author(s)
  Shimada T, Imaizumi T, et al. (全10名 10番目)
- Journal Title
  
  Circulation 110(9)
  
  Pages: 1148-1155
- Data Source
  KAKENHI-PROJECT-15659191
[Journal Article] Inhibition of platelet adherence to mononuclear cells by α-tocopherol. Role of P-selectin.2004
- Author(s)
  Murohara T, Ikeda H, Otsuka Y, Aoki M, Haramaki N, Katoh A, Takajo Y, Imaizumi T
- Journal Title
  
  Circulation 110
  
  Pages: 141-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Hypertensive myocardial fibrosis and diastolic dysfunction-Another model of inflammation-.2004
- Author(s)
  Kuwahara F, Kai H, Tokuda K, Takeya M, Takeshita A, Egashira K, Imaizumi T.
- Journal Title
  
  Hypertension 43(4)
  
  Pages: 739-745
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590781
[Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization..2004
- Author(s)
  Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T.
- Journal Title
  
  J Am Coll Cardiol 44(3)
  
  Pages: 661-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Roles of endogenous monocyate chemoattractant protein-1 in ischemia-induced neovascularization.2004
- Author(s)
  Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T
- Journal Title
  
  J Am Coll Cardiol 44
  
  Pages: 661-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization.2004
- Author(s)
  Niiyama H, Imaizumi T (全8名8番目)
- Journal Title
  
  J Am Coll Cardiol 44(3)
  
  Pages: 661-666
- Data Source
  KAKENHI-PROJECT-15659191
[Journal Article] Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.2004
- Author(s)
  Tokuda K, Kai H, Kuwahara F, Yasukawa H, Tahara N, Kudo H, Takemiya K, Koga M, Yamamoto T, Imaizumi T.
- Journal Title
  
  Hypertension 43(2 pt2)
  
  Pages: 499-503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth.2003
- Author(s)
  Egami K, Murohara T, Ikeda H, Shimada T, Sasaki K, Sugaya T, Ishii M, Akagi T, Matsuishi T, Imaizumi T
- Journal Title
  
  J Clin Invest 112
  
  Pages: 67-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Rescue of hypercholesterolemia-related impairment of angiogenesis by oral folate supplementation.2003
- Author(s)
  Sasaki K, Duan J, Murohara T, Ikeda H, Shintani S, Shimada T, Akita T, Egami K, Imaizumi T
- Journal Title
  
  J Am Coll Cardiol 42
  
  Pages: 364-372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Rho-kinase inhibition reduces neointima formation after vascular injury by enhancing Bax expression and apoptosis2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kusaba K, Takemiya K, Koga M, Jalalidin A, Tokuda K, Tahara N, Niiyama H, Nagata T, Kuwahara F, Imaizumi T.
- Journal Title
  
  J Cardiovasc Pharmacol 42(suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Inhibition of STAT3 prevents neointime formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells.2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kato S, Wada Y, Hanakawa Y, Hashimoto K, Yoshimura A, Imaizumi T.
- Journal Title
  
  Human Gene Ther 14(7)
  
  Pages: 601-610
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Inhibition of STAT3 prevents neointima formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells.2003
- Author(s)
  Shibata R, Kai H, Seki Y, Kato S, Wada Y, Hanakawa Y, Hashimoto K, Yoshimura A, Imaizumi T
- Journal Title
  
  Human Gene Therapy 14
  
  Pages: 601-610
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370234
[Journal Article] Sub-depressor dose of angiotensin type-1 receptor blocker inhibits TGF-β-mediated perivascular fibrosis in hypertensive rat hearts.2003
- Author(s)
  Tokuda K, Kai H, Kuwahara F, Imaizumi T
- Journal Title
  
  J Cardiovasc Pharmacol 42(suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] an IL-6 family cytokine, upregulates matrix metalloproteinase-9 through the MEK-ERK pathway in cultured smooth muscle cells.2003
- Author(s)
  Nagata T, Kai H, Shibata R, Koga M, Yoshimura A, Imaizumi T, Oncostatin M
- Journal Title
  
  Arterioscl Thromb Vasc Biol 23
  
  Pages: 588-593
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590780
[Journal Article] Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice
- Author(s)
  Ohmura H, Imaizumi T(他8人10番目)
- Journal Title
  
  Hypertens Res
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Inhibition of CaMKII/ERK-mediated eNOS phosphorylation by asymmetric dimethylarginine is novel molecular mechanism of endothelial dysfunction in chronic kidney disease mice2012
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  76th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Inhibition of CaMKII-and ERK-mediated eNOS phosphorylation impairs endothelial function in renal failure mice : New effect of asymmetric dimethylarginine2011
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Increased circulating asymmetric dimethylarginine in chronic kidney disease mice induces endothelial dysfunction by inhibiting Ca/Calmodulin-dependent protein kinase II-eNOS signaling2010
- Author(s)
  Kajimoto H, Kai H, Aoki H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Asymmetric dimethylarginine impairs endothelial function in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Imaizumi T
- Organizer
  ISN-Nexus Symposium 2010
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Smad-Msx2 pathway plays an initial role in vascular calcification in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, Imaizumi T
- Organizer
  74th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Asymmetric dimethylarginine triggers vascular dysfunction in CKD mice2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Imaizumi T
- Organizer
  Xth World Congress of the International Society for Heart Research 2010 Kyoto
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] 血清Asymmetric Dimethylarginineの増加が腎機能低下における血管内皮障害を起こす2010
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Imaizumi T
- Organizer
  47th Annual Meeting of the Japanese Society of Pediatric Cardiology and Cardiac Surgery Chiba
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] 腎不全マウスにおける血清Asymmetric Dimethylarginineの上昇が血管内皮に与える影響2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
- Organizer
  The 32^<nd> Annual Scientific Meeting of the Japanese Society of Hypertension
- Place of Presentation
  Shiga, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Asymmetric dimethylarginine is a paracrine regulator of vascular function in CKD2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
- Organizer
  The 13th Annual Scientific Meeting of the Japanese Heart Failure Society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] Asymmetric dimethylarginine triggers vasculo-renal interaction in CKD mice2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Anegawa T, Aoki H, Imaizumi T
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21390249
[Presentation] 血清Asymmetric Dimethylarginineの増加が腎不全マウスにおける内皮機能障害を起こす2009
- Author(s)
  Kajimoto H, Kai H, Yasuoka S, Aoki H, Anegawa T, Imaizumi T
- Organizer
  The 57th Annual Scientific Session of the Japanese College of Cardiology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21390249

1. TAKESHITA Akira (30038814)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. KAI Hisashi (60281531)

# of Collaborated Projects: 7 results

# of Collaborated Products: 34 results
3. 砂川賢二 (50163043)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 下川宏明 (00235681)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. MUROHARA Toyoaki (90299503)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. NIIYAMA Hiroshi (30309778)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
7. KANAIDE Hideo (80038851)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. KOYANAGI Samon (90128017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KUWAHARA Fumitaka (90279167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
10. 友池仁暢 (90112333)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 池田久雄 (50168134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KAJIMOTO Hidemi (50349700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
13. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOBAYASHI Sei (80225515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MATSUOKA Hedehiro (80248393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IWAMI Gensho (90203405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAHARA Nobuhiro (10320186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. NAGATA Tsuyoshi (70289429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YASUKAWA Hideo (60289361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 丹羽正美 (20136641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 上野光 (50260378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 服巻信也 (90248352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 江口裕之 (60279164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 加藤宏司 (70279165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 新谷理 (20309777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 佐々木健一郎 (70320190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 安岡逸 (10461435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
28. 丸岡雄二 (10190563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 稲生哲治 (10159965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 中村元臣 (60037322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 徳田圭亮 (80320191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. SUZUKI Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IMAIZUMI Tsutomu 今泉 勉

今泉 勉 イマイズミ ツトム

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Mechanism of Endothelial Dysfunction in Chronic Kidney DiseasePrincipal Investigator

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骨髄単核細胞移植療法による虚血肢の遺伝子発現変化の網羅的解析と遺伝子治療への応用Principal Investigator

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NEW TREATMENT FOR PULMONAY HYPERTENSIONPrincipal Investigator

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移植後冠動脈硬化に対する抗炎症性サイトカイン療法の試みPrincipal Investigator

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Role of brain nitric oxide in the development of experimental hypertension.Principal Investigator

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Effects of Insulin on sympethetic tonePrincipal Investigator

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IMAIZUMI Tsutomu 今泉勉

今泉勉イマイズミツトム