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Kobayashi Toshihide  小林 俊秀

… Alternative Names

KOBAYASHI Toshihide  小林 俊秀

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Researcher Number 60162004
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4811-7270
External Links
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 開拓研究所, 客員主管研究員
Affiliation (based on the past Project Information) *help 2015 – 2016: 国立研究開発法人理化学研究所, 佐甲細胞情報研究室, 客員主管研究員
2014: 国立研究開発法人理化学研究所, その他部局等, 研究員
2005 – 2013: 独立行政法人理化学研究所, 小林脂質生物学研究室, 主任研究員
2008: The Institute of Physical and Chemical Research, 基幹研究所・小林脂質生物学研究室, 主任研究員
2007: The Institute of Physical and Chemical Research, 小林脂質生物学研究室, 主任研究員 … More
2004 – 2005: 理化学研究所, フロンティア, リーダー
2003 – 2004: 独立行政法人理化学研究所, スフィンゴ脂質機能研究チーム, チームリーダー
2002 – 2003: 理化学研究所, フロンティア研究システム, リーダー
2002: 理化学研究所, スフィンゴ脂質機能研究チーム, チームリーダー
2000 – 2001: 理化学研究所, スフィンゴ脂質機能研究チーム, チームリーダー(研究職)
1995: Tohoku University, Graduate School of Science, Department of Physics, Associate, 大学院・理学研究科, 助教授
1994: 東北大学, 理学研究科, 助教授
1993 – 1994: 東北大学, 理学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy / Biological Sciences / Biophysics / Cell biology / Biological Sciences
Except Principal Investigator
Biological Sciences / Biological Sciences / Biomedical engineering/Biological material science
Keywords
Principal Investigator
コレステロール / 脂質ドメイン / 脂質プローブ / 脂質ラフト / スフィンゴミエリン / エンドサイトーシス / エンドソーム / フリップ-フロップ / 糖脂質 / スフィンゴ脂質 … More / 脂質結合性毒素 / Endocytosis / カベオレ / 脂質の非対称性 / ビス(モノアシルグリセロ)リン酸 / 膜ドメイン / リゾビスホスファチジン酸 / 形質膜 / ホスファチジルセリン / Lipid probe / Cholesterol / Lipid raft / スフィンゴリピドーシス / Flip-flop / 超高解像顕微鏡 / 細胞分裂 / 脂質の可視化 / Rab18 / 脂肪滴 / ラフト / 膜結合性毒素 / CHO細胞 / フリッパーゼ / ガングリオシド / GM1 / 膜融合 / Endosome / Lipid domain / Lipid bilayer / Biomembrane / シグナル伝達 / 膜結合毒素 / リゾビスボスファチジン酸 / 後期エンドソーム / 脂質二重層 / 生体膜 / Lipid-binding toxin / Membrane domain / Sphingomyelin / ホスファチジルエタノールアミン / 細胞極性 / MDCK細胞 / caveolae / raft / lipid domain / endosomes / cardiolipin / lysobisphosphatidic acid / cholesterol / sphingolipids / ライセニン / カルジオリピン / Phosphatidylserine / Fluorescent lipid analog / Plasma membrane / CHO cell / Membrane lipid asymmetry / Flippase / CHO / 蛍光標識脂質類似体 / 膜の非対称性 / 上皮細胞 / フリーズフラクチャー / PLIN2 / ホスホリパーゼC / ラマン分光 / インフルエンザ / 脂質結合毒素 / 電子顕微鏡 / ジアシルグリセロール / セカンドメッセンジャー / X線散乱 / 免疫電子顕微鏡 / ホスファチジルイノシトール4,5-ビスリン酸 / ACAT / 肝細胞 / ADRP / VLDL / ApoB / 脂質のポリモルフィズム / 脂質非対称性 / バース病 / 脂質生合成 / ミトコンドリア / リポソーム / EGFレセプター / SREBP / rab11 / 細胞密度 / 蛍光標識脂質 / リサイクリングエンドソーム / 低分子量Gタンパク質 / 抗ガン剤 / 多剤耐性 / P-糖蛋白質 / MAP-2 / GD3 / 間接蛍光体法 / 樹状突起 / 軸索 / 海馬 / 神経細胞 / GM3 / MDCK / コレラ毒素 / 海馬ニューロン / 膜形成 / ニューロン / 脂質輸送 / 小胞輸送 … More
Except Principal Investigator
スフィンゴ糖脂質 / マイクロドメイン / 食胞形成 / 非定型抗酸菌 / 貪食 / ラクトシルセラミド / 好中球 / グリコシグナリングドメイン / 分化 / neurosphere / DGCR8 / 22q11.2欠乏症候群 / 神経分化 / 22q11.2欠失症候群 / コピー数多型 / miRNA / 終末糖化産物 / 神経発達 / カルボニルストレス / iPS細胞 / 22q11.2欠失 / 統合失調症 / phospholipids / phase transition / target cell / drug delivery system / DSC / peptides / carrier liposome / membrane fusion / 医用工学 / 細胞 / 蛍光測定 / リポソーム / 担体リポソーム / リン脂質 / 相転移 / 標的細胞 / ドラッグディリバリシステム / 示差走査熱量測定 / ペプチド / 相体リポソーム / 膜融合 / 蛍光標識 Less
  • Research Projects

    (22 results)
  • Research Products

    (133 results)
  • Co-Researchers

    (24 People)
  •  Molecular dissection of organization and dynamics of membrane lipid domainsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Institute of Physical and Chemical Research
  •  Imaging the opposite side of lipid raftPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Elucidation of pathologic mechanism using iPS cells derived from schizophrenia patients

    • Principal Investigator
      YOSHIKAWA TAKEO
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  Molecular dissection of the organization and dynamics of lipid domains in biomembranesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The Institute of Physical and Chemical Research
  •  コレステロールによる細胞内輸送の制御Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Molecular dissection of organization and dynamics of lipid domains in biomembranesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The Institute of Physical and Chemical Research
  •  脂質特異的プローブを用いた細胞内脂質の分布と動態の解析Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Molecular dissection of organization and dynamics of lipid domains in biomembranesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      RIKEN
  •  病原性抗酸菌の好中球食胞形成機構におけるリピッドラフトの役割の解明

    • Principal Investigator
      岩渕 和久
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  脂質特異的プローブを用いた細胞内脂質の分布と動態の解析Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  好中球の貧食におけるリピッドラフトの役割の解明

    • Principal Investigator
      岩渕 和久
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  好中球の貪食におけるリピッドラフトの役割の解明

    • Principal Investigator
      岩渕 和久
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  Molecular dissection of organization and dynamics of membrane lipid domainsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      RIKEN
  •  Molecular Dissection of the Organization and the Dynamics of Intracellular Lipid DomainsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      RIKEN
  •  糖脂質の細胞内輸送Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  フリップ-フロップを介した物質輸送Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  小胞輸送経路における脂質の動態Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  培養海馬ニューロンの膜形成における糖脂質の機能の解析Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  Developmental Research for Peptides Inducing Membrane Fusion between Liposomes and Cells

    • Principal Investigator
      OHKI Kazuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      TOHOKU UNIVERSITY
  •  非対称標識した脂質小胞を用いた小胞輸送経路での脂質の動態の解析Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  培養海馬ニューロンの膜形成における糖脂質の機能の解析Principal Investigator

    • Principal Investigator
      小林 俊秀
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  STUDIES ON ANIMAL CELL SURFACE PHOSPHATIDYLSERINE-FLIPPASEPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshihide
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      TOHOKU UNIVERSITY

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent Other

  • [Book] The use of lipid-binding toxins to study distribution and dynamics of sphingolipids and cholesterol (review). in Probes and Tags to Study Biomolecular Function (Miller LW. ed.) pp. 53-71.2008

    • Author(s)
      Ishitsuka R, Kobayashi T
    • Publisher
      Wiley-VCH, Weinheim
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Book] Sphingolipid Biology2006

    • Author(s)
      Kobayashi T
    • Total Pages
      531
    • Publisher
      Springer-Verlag Tokyo
    • Data Source
      KAKENHI-PROJECT-18050040
  • [Book] Sphingolipid Biology 20052006

    • Author(s)
      Kobayashi T
    • Total Pages
      531
    • Publisher
      Springer Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390025
  • [Book] Sphingolipid Biology2006

    • Author(s)
      Kobayashi T
    • Total Pages
      531
    • Publisher
      Springer-Verlag Tokyo
    • Data Source
      KAKENHI-PROJECT-17390025
  • [Book] 化学と生物実験ライン54細胞生物学実験法 III 細胞解析法-IV2005

    • Author(s)
      小林俊秀
    • Total Pages
      110
    • Publisher
      廣川書店
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390025
  • [Book] Cell Biology : A Laboratory Handbook2005

    • Author(s)
      Kobayashi T
    • Publisher
      Elsevier, Burlington
    • Data Source
      KAKENHI-PROJECT-16044247
  • [Book] Cell Biology : A Laboratory Handbook2005

    • Author(s)
      Kobayashi T
    • Publisher
      Elsevier, Burlington
    • Data Source
      KAKENHI-PROJECT-17390025
  • [Book] Cell Biology : A Laboratory Handbook2005

    • Author(s)
      Kobayashi T
    • Publisher
      Elsevier(in press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Journal Article] Photoswitchable phospholipid FRET acceptor: Detergent free intermembrane transfer assay of fluorescent lipid analogs.2017

    • Author(s)
      Sumi M, Makino A, Inaba T, Sako Y, Fujimori F, Greimel P, Kobayashi T
    • Journal Title

      Sci Rep

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Journal Article] Acute accumulation of free cholesterol induces the degradation of perilipin 2 and Rab18-dependent fusion of ER and lipid droplets in cultured human hepatocytes.2016

    • Author(s)
      Makino A, Hullin-Matsuda F, Murate M, Abe M, Tomishige N, Fukuda M, Yamashita S, Fujimoto T, Vidal H, Lagarde M, Delton I, Kobayashi T.
    • Journal Title

      Mol Biol Cell

      Volume: 27 Issue: 21 Pages: 3293-3304

    • DOI

      10.1091/mbc.e15-10-0730

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15H02500, KAKENHI-PROJECT-15K07957, KAKENHI-PROJECT-15K08167
  • [Journal Article] Detection of sphingomyelin clusters by Raman spectroscopy.2016

    • Author(s)
      Shirota K, Yagi K, Inaba T, Li PC, Murata M, Sugita Y, Kobayashi T.
    • Journal Title

      Biophys J

      Volume: 111 Issue: 5 Pages: 999-1007

    • DOI

      10.1016/j.bpj.2016.07.035

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Journal Article] Detectors for evaluating the cellular landscape of sphingomyelin- and cholesterol-rich membrane domains2016

    • Author(s)
      Kishimoto T*, Ishitsuka R*, Kobayashia T. * equally contributed
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

      Volume: in press Issue: 8 Pages: 812-829

    • DOI

      10.1016/j.bbalip.2016.03.013

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24790104, KAKENHI-PROJECT-25293015
  • [Journal Article] Pore-forming toxins: Properties, diversity, and uses as tools to image sphingomyelin and ceramide phosphoethanolamine.2016

    • Author(s)
      Yamaji-Hasegawa A, Hullin-Matsuda F, Greimel P, Kobayashi T.
    • Journal Title

      Biochim. Biophys Acta

      Volume: 1858 Issue: 3 Pages: 576-592

    • DOI

      10.1016/j.bbamem.2015.10.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Journal Article] Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells2016

    • Author(s)
      Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H.
    • Journal Title

      Stem Cell Reports.

      Volume: 6 Issue: 3 Pages: 422-35

    • DOI

      10.1016/j.stemcr.2016.01.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06780, KAKENHI-PROJECT-15K09849, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-26830018, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-26870074, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-16K08280
  • [Journal Article] Phospholipase Cβ1 induces membrane tubulation and is involved in caveolae formation.2016

    • Author(s)
      Inaba T, Kishimoto T, Murate M, Tajima T, Sakai S, Abe M, Makino A, Tomishige N, Ishitsuka R, Ikeda Y, Takeoka S, Kobayashi T.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 113 Issue: 28 Pages: 7834-7839

    • DOI

      10.1073/pnas.1603513113

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293015, KAKENHI-PROJECT-15K07957, KAKENHI-PROJECT-15K08167
  • [Journal Article] Evaluation of aegerolysins as novel tools to detect and visualize ceramide phosphoethanolamine, a major sphingolipid in invertebrates2015

    • Author(s)
      Bhat HB, Ishitsuka R, Inaba T, Murate M, Abe M, Makino A, Kohyama-Koganeya A, Nagao K, Kurahashi A, Kishimoto T, Tahara M, Yamano A, Nagamune K, Hirabayashi Y, Juni N, Umeda M, Fujimori F, Nishibori K, Yamaji-Hasegawa A, Greimel P, Kobayashi T.
    • Journal Title

      FASEB J

      Volume: 29(9) Issue: 9 Pages: 3920-34

    • DOI

      10.1096/fj.15-272112

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07957, KAKENHI-PROJECT-15K08167, KAKENHI-PROJECT-15K14476, KAKENHI-PLANNED-15H05930, KAKENHI-PLANNED-23117007, KAKENHI-PROJECT-24790104, KAKENHI-PROJECT-25293015, KAKENHI-PROJECT-25293012, KAKENHI-PROJECT-15H04726
  • [Journal Article] Asymmetric diacylglycerol dynamics on the cytoplasmic and luminal sides of a single endomembrane in living cells2015

    • Author(s)
      Ueda Y, Ogiso H, Sato M, Umezawa Y, Okazaki T, Kobayashi T
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 12960-12960

    • DOI

      10.1038/srep12960

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-1.2015

    • Author(s)
      Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki, Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto and Yuji Owada
    • Journal Title

      Glia

      Volume: 63 Issue: 5 Pages: 780-794

    • DOI

      10.1002/glia.22784

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590263, KAKENHI-PROJECT-25670274, KAKENHI-PROJECT-26860134, KAKENHI-PROJECT-15K09814, KAKENHI-PROJECT-26350122, KAKENHI-PROJECT-15K16206, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-24116002, KAKENHI-PUBLICLY-26116720, KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-24390047, KAKENHI-ORGANIZER-24116001
  • [Journal Article] Visualization of lipid membrane reorganization induced by a pore-forming toxin using high-speed atomic force microscopy2015

    • Author(s)
      Yilmaz N, Kobayashi T
    • Journal Title

      ACS Nano

      Volume: 9 Issue: 8 Pages: 7960-7967

    • DOI

      10.1021/acsnano.5b01041

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Journal Article] Transbilayer distribution of lipids at nano scale.2015

    • Author(s)
      Murate M, Abe M, Kasahara K, Iwabuchi K, Umeda M, Kobayashi T
    • Journal Title

      J Cell Sci

      Volume: 128 Pages: 1627-1638

    • DOI

      10.1242/jcs.163105

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461011, KAKENHI-PROJECT-26440071, KAKENHI-PROJECT-15K07957, KAKENHI-PROJECT-15K08167, KAKENHI-PROJECT-25293015
  • [Journal Article] Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.2014

    • Author(s)
      Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T.
    • Journal Title

      Hum Mol Genet

      Volume: 23 Issue: 24 Pages: 6495-6511

    • DOI

      10.1093/hmg/ddu369

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-24390047, KAKENHI-PROJECT-26350122
  • [Journal Article] Lipid compartmentalization in the endosome system2014

    • Author(s)
      Hullin-Matsuda F, Taguchi T, Greimel P, Kobayashi T.
    • Journal Title

      Sem Cell Dev Biol

      Volume: (in press) Pages: 48-56

    • DOI

      10.1016/j.semcdb.2014.04.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24657143, KAKENHI-PROJECT-25293015, KAKENHI-PROJECT-25460081
  • [Journal Article] Imaging local sphingomyelin-rich domains in the plasma membrane using specific probes and advanced microscopy2014

    • Author(s)
      Abe M, Kobayashi T.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1841 Issue: 5 Pages: 720-726

    • DOI

      10.1016/j.bbalip.2013.07.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Journal Article] Role for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migration2013

    • Author(s)
      Kato U, Inadome H, Yamamoto M, Emoto K, Kobayashi T, and M. Umeda
    • Journal Title

      J Biol Chem

      Volume: 288 Pages: 4922-4934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Sphingomyelin regulates the transbilayer movement of diacylglycerol in the plasma membrane of Madin-Darby canine kidney cells2013

    • Author(s)
      Ueda Y, Makino A, Murase-Tamada K, Sakai S, Inaba T, Hullin-Matsuda F, Kobayashi T.
    • Journal Title

      FASEB J

      Volume: 27 Issue: 8 Pages: 3284-3297

    • DOI

      10.1096/fj.12-226548

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24657143, KAKENHI-PROJECT-24700348, KAKENHI-PROJECT-25460081
  • [Journal Article] Visualization of cholesterol-rich membrane domains with fluorescently-labeled theonellamides.2013

    • Author(s)
      Nishimura, S., Ishii, K., Iwamoto, K., Matsunaga, S., Ohno-Iwashita, Y., Sato, S. B., Kakeya, H., Kobayashi, T. & Yoshida, M.
    • Journal Title

      PLOS ONE

      Volume: 8 Issue: 12 Pages: e83716-e83716

    • DOI

      10.1371/journal.pone.0083716

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102515, KAKENHI-PROJECT-24657143, KAKENHI-PROJECT-25702048
  • [Journal Article] Real-Time Visualization of Assembling of a Sphingomyelin-Specific Toxin.2013

    • Author(s)
      N. Yilmaz, T. Yamada, P. Greimel, T. Uchihashi, T. Ando, T. Kobayashi
    • Journal Title

      Biophys. J.

      Volume: 105 Issue: 6 Pages: 1397-1405

    • DOI

      10.1016/j.bpj.2013.07.052

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21113002, KAKENHI-PLANNED-23115008, KAKENHI-PROJECT-24227005, KAKENHI-PROJECT-24241048, KAKENHI-PROJECT-24657143, KAKENHI-PROJECT-25293015
  • [Journal Article] Sphingomyelin regulates the transbilayer movement of diacylglycerol in the plasma membrane of Madin-Darby canine kidney cells2013

    • Author(s)
      Ueda Y, Makino A, Murase-Tamada K, Sakai S, Inaba T, Hullin-Matsuda F, and T. Kobayashi.
    • Journal Title

      FASEB J

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Spectroscopic evidence for the unusual stereochemical configuration of an endosome-specific lipid2012

    • Author(s)
      Tan H-H, Makino A, Sudesh K, Greimel P, and T. Kobayashi
    • Journal Title

      Angew Chem Int Ed

      Volume: 51 Pages: 533-535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] A role for sphingomyelin-rich lipid domains in the accumulation of PIP2 to the cleavage furrow during cytokinesis2012

    • Author(s)
      Abe M, Makino A, Hullin-Matsuda F, Kamijo K, Ohno-Iwashita Y, Hanada K, Mizuno H, Miyawaki A, and T. Kobayashi
    • Journal Title

      Mol Cell Biol

      Volume: 32 Pages: 1396-1407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Nano-mechanical recognition of sphingomyelin-rich membrane domains by atomic force microscopy2012

    • Author(s)
      Wang T, Shogomori H, Hara M, Yamada T, and T. Kobayashi
    • Journal Title

      Biochemistry

      Volume: 51 Pages: 74-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Limonoid compounds inhibit sphingomyelin biosynthesis by preventing CERT protein-dependent extraction of ceramides from the endoplasmic reticulum2012

    • Author(s)
      Hullin-Matsuda F, Tomishige N, Sakai S, Ishitsuka R, Ishii K, Makino A, Greimel P, Abe M, Laviad EL, Lagarde M, Vidal H, Saito T, Osada H, Hanada K, Futerman AH, and T. Kobayashi
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 24397-24411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Rapid flip-flop motions of diacylglycerol and ceramide in phospholipid bilayers2012

    • Author(s)
      Ogushi F, Ishitsuka R, Kobayashi T, and Y. Sugita
    • Journal Title

      Chem Phys Lett

      Volume: 522 Pages: 96-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells2012

    • Author(s)
      Yachi R, Uchida Y, Balakrishna, BH, Anderluh G, Kobayashi T, Taguchi T, Arai H.
    • Journal Title

      Genes Cells

      Volume: 17 Pages: 720-727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Journal Article] Fluorescent probes for superresolution imaging of lipid domains on the plasma membrane2011

    • Author(s)
      Mizuno H, Abe M, Dedecker P, Makino A, Rocha S, Ohno-Iwashita Y, Hofkens J, Kobayashi T, and A. Miyawaki
    • Journal Title

      Chem Sci

      Volume: 2 Pages: 1548-1553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Fluorescence image screening for chemical compounds modifying cholesterol metabolism and distribution2011

    • Author(s)
      Ishitsuka R, Saito T, Osada H, Ohno-Iwashita Y, and T. Kobayashi
    • Journal Title

      J Lipid Res.

      Volume: 52 Pages: 2084-2094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Multiplex analysis of sphingolipids using amine-reactive tags (iTRAQ)2011

    • Author(s)
      Nabetani T, Makino A, Hullin-Matsuda F, Hirakawa T, Takeoka S, Okino N, Ito M, Kobayashi T, and Y. Hirabayashi
    • Journal Title

      J Lipid Res

      Volume: 52 Pages: 1294-1302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Marine antifungal theonellamides target 3β-hydroxysterol to activate Rho1 signaling2010

    • Author(s)
      Nishimura S, Arita Y, Honda M, Iwamoto K, Matsuyama A, Shirai A, Kawasaki H, Kakeya H,Kobayashi T, Matsunaga S, and M. Yoshida
    • Journal Title

      Nat Chem Biol

      Volume: 6 Pages: 519-526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane2010

    • Author(s)
      Murate M, Hayakawa T, Ishii K, Inadome H, Greimel P, Watanabe Y, Nagatsuka Y, Ito K, Ito Y, Takahashi H, Hirabayashi Y, and T. Kobayashi
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 4732-4739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Journal Article] Visualization of Phospholipid Particle Fusion Induced by Duramycin2009

    • Author(s)
      Matsunaga S, Matsunaga T, Iwamoto K, Yamada T, Shibayama M, Kawai M, Kobayashi T
    • Journal Title

      Langmuir (in press)

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Binding of laminin-1 to GM1 ganglioside in lipid rafts is critical for neurite outgrowth2009

    • Author(s)
      Ichikawa N, Iwabuchi K, Kurihara H, Ishii K, Kobayashi T, Sasaki T, Hattori N, Mizuno Y, Hozumi K, Yamada Y, Arikawa-Hirasawa E
    • Journal Title

      J. Cell Sci. 122

      Pages: 289-299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Cholesterol regulation of rab-mediated sphingolipid endocytosis2009

    • Author(s)
      Takahashi M, Kobayashi T
    • Journal Title

      Glycoconj. J (in press)

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] 脂質ラフトは存在するか2009

    • Author(s)
      小林俊秀
    • Journal Title

      生化学 81

      Pages: 17-23

    • NAID

      10024915623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Fyn tyrosine kinase regulates the surface expression of GPI-linked ephrin via the modulation of sphingomyelin metabolism2009

    • Author(s)
      Baba A, Akagi K, Takayanagi M, Flanagan JG, Kobayashi T, Hattori M
    • Journal Title

      J. Biol. Chem 284

      Pages: 9206-9214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Glycosphingolipid deficiency increases the sterol regulatory element-mediated gene transcription2009

    • Author(s)
      Ishitsuka R, Hirabayashi Y, Kobayashi T
    • Journal Title

      Biochem. Biophys. Res. Commun 378

      Pages: 240-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Selective decrease of bis (monoacylglycero)phosphate content in macrophages by high supplementation with docosahexaenoic acid2009

    • Author(s)
      Bouvier J, Zemski Berry KA, Hullin-Matsuda F, Makino A, Michaud S, Geloen A, Murphy RC, Kobayashi T, Lagarde M, Delton-Vandenbroucke I
    • Journal Title

      J. Lipid Res 50

      Pages: 243-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Lipid Bilayers at the Gel Interface for Single Ion Channel Recordings2008

    • Author(s)
      Ide T, Kobayashi T, Hirano M
    • Journal Title

      Anal. Chem. 80

      Pages: 7792-7795

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Lysenin: a sphingomyelin specific pore-forming toxin2008

    • Author(s)
      Shogomori H, Kobayashi T
    • Journal Title

      Biochim. Biophys. Acta 1780

      Pages: 612-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Cholesterol and lipid/protein ratio control the oligomerization of a sphingomyelin-specific toxin, lysenin2007

    • Author(s)
      Ishitsuka R, Kobayashi T
    • Journal Title

      Biochemistry 46

      Pages: 1495-1502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Cholesterol controls lipid endocytosis through Rab112007

    • Author(s)
      Takahashi M, Murate M, Fukuda M, Sato SB, Ohta A, Kobayashi T
    • Journal Title

      Mol. Biol. Cell 18

      Pages: 2667-2677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Increased lipid rafts and accelerated lipopolysaccharide -induced tumor necrosis factor alpha secretion in Abca1-deficient macrophages2007

    • Author(s)
      Koseki M, Hirano KI, Masuda D, Ikegami C, Tanaka M, Ota A, Sandoval JC, Nakagawa-Toyama Y, Sato SB, Kobayashi T, Shimada Y, Ohno-Iwashita Y, Matsuura F, Shimomura I, Yamashita S
    • Journal Title

      J. Lipid Res 48

      Pages: 299-306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] e novo biosynthesis of the late endosome lipid, bis(monoacyl- glycero)phosphate2007

    • Author(s)
      Hullin-Matsuda F, Kawasaki K, Delton -Vandenbroucke I, Xu Y, Nishijima M, Lagarde M, Schlame M, Kobayashi T
    • Journal Title

      D. J. Lipid Res 48

      Pages: 1997-2008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Structural characterization of N-lignoceroyl (C24:0) sphingomyelin bilayer membranes : A reevaluation2007

    • Author(s)
      Takahashi H, Hayakawa T, Kawasaki Y, Ito K, Fujisawa T, Kodama M, Kobayashi T
    • Journal Title

      J.Appl.Cryst 40

    • NAID

      120000908540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Curvature-dependent recognition of ethanolamine phospholipids by duramycin and cinnamycin2007

    • Author(s)
      Iwamoto K, Hayakawa T, Murate M, Makino A, Ito K, Fujisawa T, Kobayashi T
    • Journal Title

      Biophys. J 93

      Pages: 1608-1619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] EC-STM observation on electrochemical response of fluidic phospholipid monolayer on Au(111) modified with 1-octanethiol2007

    • Author(s)
      Matsunaga S, Yokomori R, Ino D, Yamada T, Kawai M, Kobayashi T
    • Journal Title

      Electrochem. Commun 9

      Pages: 645-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] pH-dependent formation of membranous cytoplasmic body-like structure of ganglioside GM1/bis(monoacylglycero)phosphate mixed membranes2007

    • Author(s)
      Hayakawa T, Makino A, Murate M, Sugimoto I, Hashimoto Y, Takahashi H, Ito K, Fujisawa T, Matsuo H, Kobayashi T
    • Journal Title

      Biophys. J 92

    • NAID

      120000908535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Monitoring the distribution and dynamics of signaling microdomains in living cells with lipid-specific probes2007

    • Author(s)
      Hullin-Matsuda F, Kobayashi T
    • Journal Title

      Cell. Mol. Life Sci 64

      Pages: 2492-2504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Stage specific association of apolipoprotein A-I and E in developing mouse retina2007

    • Author(s)
      Kurumada S, Onishi A, Imai H, Ishii K, Kobayashi T, Sato SB
    • Journal Title

      Invest. Opht. Vis.Sci 48

      Pages: 1815-1823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Anti-bis(monoacylglycero) phosphate antibody induces the accumulation of acetylated-low density lipoprotein-derived cholesterol in cultured macrophages2007

    • Author(s)
      Delton-Vandenbroucke I, Bouvier J, Makino A, Besson N, Pageaux J-F, Lagarde M, Kobayashi T
    • Journal Title

      J. Lipid Res 48

      Pages: 543-552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Journal Article] Lipid rafts. New tools and a new component2006

    • Author(s)
      Kobayashi T
    • Journal Title

      Biol Pharm Bull 29

      Pages: 1526-1531

    • NAID

      110005663983

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390025
  • [Journal Article] Lipid rafts. New tools and a new component2006

    • Author(s)
      Kobayashi T
    • Journal Title

      Biol. Pharm. Bull. 29

      Pages: 1526-1531

    • NAID

      110005663983

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390025
  • [Journal Article] Spatial and functional heterogeneity of sphingolipid-rich membrane domains.2005

    • Author(s)
      Kiyokawa E, Baba T, Otsuka N, Makino A, Ohno S, Kobayashi T.
    • Journal Title

      J.Biol.Chem (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Journal Article] A lipid-specific toxin reveals heterogeneity of sphingomyelin-containing membranes.2004

    • Author(s)
      Ishitsuka R, Yamaji-Hasegawa A, Makino A, Hirbayashi Y, Kobayashi T.
    • Journal Title

      Biophys.J. 86

      Pages: 296-307

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Journal Article] Recognition of sphingomyelin by lysenin and lysenin-related proteins.2004

    • Author(s)
      Kiyokawa E, Makino A, Ishii K, Otsuka N, Yamaji-Hasegawa A, Kobayashi T.
    • Journal Title

      Biochemistry 43

      Pages: 9766-9773

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Journal Article] Distribution and transport of cholesterol-rich membrane domains monitored by a membrane-impermeant fluorescent polyethylene glycol-derivatized cholesterol.2004

    • Author(s)
      Sato SB, Ishii K, Makino A, Iwabuchi K, Yamaji-Hasegawa A, Senoh Y, Nagaoka I, Sakuraba H, Kobayashi T.
    • Journal Title

      J.Biol.Chem 279

      Pages: 23790-23796

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Journal Article] Cinnamycin (Ro09-0198) promotes cell binding and toxicity by inducing transbilayer lipid movement.2003

    • Author(s)
      Makino A, Baba T, Fujimoto K, Iwamoto K, Yano Y, Terada N, Ohno S, Sato SB, Ohta A, Umeda M, Matsuzaki K, Kobayashi T.
    • Journal Title

      J.Biol.Chem 278

      Pages: 3204-3209

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Journal Article] Oligomerization and pore formation of a sphingomyelin-specific toxin, lysenin.2003

    • Author(s)
      Yamaji-Hasegawa A, Makino A, Baba T, Senoh Y, Kimura-Suda H, Sato B S, Terada N, Ohno S, Kiyokawa E, Umeda M, Kobayashi T.
    • Journal Title

      J.Biol.Chem 278

      Pages: 22762-22770

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Patent] 新規なタンパク質およびその利用2010

    • Inventor(s)
      小林俊秀
    • Industrial Property Rights Holder
      理化学研究所
    • Filing Date
      2010-05-14
    • Data Source
      KAKENHI-PUBLICLY-21113530
  • [Patent] 新規なタンパク質およびその利用2010

    • Inventor(s)
      小林俊秀
    • Industrial Property Rights Holder
      理化学研究所
    • Filing Date
      2010-05-14
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Patent] コレステロール検出試薬2002

    • Inventor(s)
      小林 俊秀
    • Industrial Property Rights Holder
      理化学研究所
    • Industrial Property Number
      2002-160277
    • Filing Date
      2002-05-31
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Patent] Sphingomyelin detecting probe2002

    • Inventor(s)
      Toshihide Kobayashi
    • Industrial Property Rights Holder
      RIKEN
    • Filing Date
      2002-05-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370753
  • [Patent] コレステロール検出試薬2002

    • Inventor(s)
      小林俊秀
    • Industrial Property Rights Holder
      理化学研究所
    • Filing Date
      2002-05-31
    • Acquisition Date
      2006-08-11
    • Data Source
      KAKENHI-PROJECT-18050040
  • [Presentation] Phospholipase C beta 1 induces membrane tubulation and is involved in caveolae formation2016

    • Author(s)
      Inaba T, Kishimoto T, Murate M, Tajima T, Sakai S, Abe M, Makino A, Tomishige N, Ishitsuka R, Ikeda Y, Takeoka S, Kobayashi T
    • Organizer
      57th International Conference on the Bioscience of Lipids
    • Place of Presentation
      Chamonix Mont-Blanc, France
    • Year and Date
      2016-09-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Imaging lipids and lipid domains2016

    • Author(s)
      Kobayashi T
    • Organizer
      Sphingonet’s International Colloquium
    • Place of Presentation
      Amsterdam, Netherland
    • Year and Date
      2016-01-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Phosphatidylglycerol analog regulates the synthesis of the endosome-specific lipid bis(monoacylglycero)phosphate2016

    • Author(s)
      Tan HH, Hullin-Matsuda F, Lim SR, Sudesh K, Gram LH, Greimel P, Kobayashi T
    • Organizer
      57th International Conference on the Bioscience of Lipids
    • Place of Presentation
      Chamonix Mont-Blanc, France
    • Year and Date
      2016-09-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] A novel sphingomyelin/cholesterol domain-specific probe reveals the dynamics of the membrane domains during virus release2016

    • Author(s)
      Makino A, Abe M, Ishitsuka R, Murate M, Kishimoto T, Sakai S, Hullin-Matsuda F, Inaba T, Greimel P, Kobayashi T
    • Organizer
      12th Gerli international lipidomics meeting
    • Place of Presentation
      Toulouse, France
    • Year and Date
      2016-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Elucidation of the natural regioisomer of the endosome-specific lipid bis(monoacylglycero)phosphate2016

    • Author(s)
      Lim SR, Tan HH, Hullin-Matsuda F, Sudesh K, Gram LH, Greimel P, Kobayashi T
    • Organizer
      57th International Conference on the Bioscience of Lipids
    • Place of Presentation
      Chamonix Mont-Blanc, France
    • Year and Date
      2016-09-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Phosphatidylglycerol analog regulates the synthesis of the endosome-specific and fusion enhancing lipid bis(monoacylglycero)phosphate2016

    • Author(s)
      Tan HH, Hulin-Matsuda F, Lim SR, Sudesh K, Gam LH, Greimel P, Kobayashi T
    • Organizer
      12th Gerli international lipidomics meeting
    • Place of Presentation
      Toulouse, France
    • Year and Date
      2016-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Cellular localization of sphingomyelin clusters2016

    • Author(s)
      Kobayashi T
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2016-03-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Imaging lipids and lipid domains2016

    • Author(s)
      Kobayashi T
    • Organizer
      Joint meeting of the membrane sections of the French and German Biophysical Societies
    • Place of Presentation
      Bad Herrenalb, Germany
    • Year and Date
      2016-04-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Imaging lipids and lipid domains2015

    • Author(s)
      Kobayashi T
    • Organizer
      11th GERLI Lipidomics Meeting
    • Place of Presentation
      Strasbourg France
    • Year and Date
      2015-10-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] 脂質のイメージング2014

    • Author(s)
      小林俊秀
    • Organizer
      第1回JFAS講演会
    • Place of Presentation
      秋葉原
    • Year and Date
      2014-01-11
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 膜を横切る脂質の運動、フリップフロップについて2013

    • Author(s)
      小林俊秀
    • Organizer
      第10回「生体膜・コロイド研究の最前線」
    • Place of Presentation
      東海村
    • Invited
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] Free cholesterol loading induces the degradation of perilipin 2 and rab18-de pendent abnormal lipidation of apolipoprotein B in cultured hepatocytes2013

    • Author(s)
      Makino A, Hullin-Matsuda F, Murate M, Abe M, Fukuda M, Yamashita S, Fujimoto T, Vidal H, Lagarde M, Delton-Vandenbroucke I, Kobayashi T.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] "Imaging lipids and lipid domains"2^<nd> Mini Symposium"Protein-lipid interactions"2013

    • Author(s)
      Kobayashi T.
    • Organizer
      Piran
    • Place of Presentation
      Slovenia
    • Year and Date
      2013-09-06
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 細胞分裂時におけるホスファチジルイノシトール4,5_二リン酸の分裂溝への局在に対するスフィンゴミエリンドメインの役割2013

    • Author(s)
      小林俊秀、阿部充宏、牧野麻美、ウラン松田フランソワーズ
    • Organizer
      第90回生理学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 細胞分裂時におけるホスファチジルイノシトール4,5-二リン酸の分裂溝への局在に対するスフィンゴミエリンドメインの役割2013

    • Author(s)
      小林俊秀
    • Organizer
      第90回日本生理学会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Protein probes for studying lipid domains2013

    • Author(s)
      Toshihide Kobayashi
    • Organizer
      The Fourteenth International Membrane Research Forum
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 「膜を横切る脂質の運動、フリップフロップについて」Workshop : CROSSroads of Users and J-PARC2013

    • Author(s)
      小林俊秀
    • Organizer
      第10回「生体膜・コロイド研究の最前線」
    • Place of Presentation
      茨城
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 膜を横切る脂質の運動、フリップフロップについて2013

    • Author(s)
      小林俊秀
    • Organizer
      第10回「生体膜・コロイド研究の最前線」
    • Place of Presentation
      東海村
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Protein probes for studying lipid domains2013

    • Author(s)
      Toshihide Kobayashi
    • Organizer
      The fourteenth international membrane research forum
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Free cholesterol loading induces the degradation of perilipin 2 and rab18-de pendent abnormal lipidation of apolipoprotein B in cultured hepatocytes2013

    • Author(s)
      Makino A, Hullin-Matsuda F, Murate M, Abe M, Fukuda M, Yamashita S, Fujimoto T, Vidal H, Lagarde M, Delton-Vandenbroucke I, Kobayashi T
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] エンドソーム特異的脂質の構造、代謝、機能2012

    • Author(s)
      小林俊秀
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] A role for sphingomyelin-rich lipid domains in the accumulation of phosphatidylinositol-4,5-bisphosphate to the cleavage furrow during cytokinesis2012

    • Author(s)
      Abe, M., A. Makino, F. Hullin-Matsuda, and T. Kobayashi
    • Organizer
      Lipid-Protein Interactions in Membranes: Implications for Health and Disease
    • Place of Presentation
      Hyderabad, India
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] 細胞質分裂におけるスフィンゴミエリンドメインの役割2012

    • Author(s)
      小林俊秀
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] A role for sphingomyelin-rich lipid domains in the accumulation of phosphatidylinositol-4,5-bisphosphate to the cleavage furrow during cytokinesis2012

    • Author(s)
      Toshihide Kobayashi
    • Organizer
      Lipid-Protein Interactions in Membranes: Implications for Health and Disease
    • Place of Presentation
      Hyderabad
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] 細胞質分裂におけるスフィンゴミエリンドメインの役割2012

    • Author(s)
      阿部充宏、牧野麻美、ウラン松田フランソワーズ、小林俊秀
    • Organizer
      第85回生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 細胞質分裂におけるスフィンゴミエリンドメインの役割2012

    • Author(s)
      阿部充宏、牧野麻美、ウラン松田フランソワーズ、小林俊秀
    • Organizer
      第85回生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Session chair's overview2012

    • Author(s)
      Kobayashi, T.
    • Organizer
      Gordon Reseach Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] エンドソーム特異的脂質の構造、代謝、機能2012

    • Author(s)
      小林俊秀
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] エンドソーム特異的脂質の構造、代謝、機能2012

    • Author(s)
      小林俊秀
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 脂質のダイナミズムを見る-脂質・蛋白質相互作用の解析2011

    • Author(s)
      小林俊秀
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Imaging lipids and lipid domains2011

    • Author(s)
      Kobayashi, T.
    • Organizer
      International ERATO Symposium on Lipid Structures in and around Proteins
    • Place of Presentation
      Osaka
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Imaging lipids and lipid domains2011

    • Author(s)
      Kobayashi T.
    • Organizer
      International ERATO Symposium on Lipid Structures in and around Proteins
    • Place of Presentation
      阪急エキスポパーク(大阪)(招待講演)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Imaging lipid domains2011

    • Author(s)
      Kobayashi T.
    • Organizer
      30^<th> Naito conference, "Membrane Dynamics and Lipid Biology [II]"
    • Place of Presentation
      シャトレーゼガトーキングダム札幌(札幌)(招待講演)
    • Year and Date
      2011-06-29
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Imaging lipid domains Naito conference,2011

    • Author(s)
      Kobayashi, T., Abe, M., Ishitsuka, R., Kishimoto, T., Makino, A., Hullin-Matsuda, F.,and M. Murate
    • Organizer
      30^(th)Naito conference "Membrane Dynamics and Lipid Biology [II]"
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Visualization of lipids and lipid domains2011

    • Author(s)
      小林俊秀、阿部充宏、岸本拓磨、牧野麻美、Hullin-Matsuda Francoise、石塚玲子、村手源英
    • Organizer
      第53回日本脂質生化学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Tool box for imaging lipids and lipid domains (I) (II)2010

    • Author(s)
      Kobayashi, T.
    • Organizer
      ISN International School: Lipidomics in the nervous system cells
    • Place of Presentation
      Catania, Italy,
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] 脂質ラフトのイメージング2010

    • Author(s)
      小林俊秀
    • Organizer
      第3回セラミド研究会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Imaging of membrane heterogeneity2010

    • Author(s)
      Kobayashi, T.
    • Organizer
      4^<th> ISN Special Conference on Membrane Domains in CNS physiology and pathology
    • Place of Presentation
      Erice, Italy
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-22390018
  • [Presentation] Imaging of membrane heterogeneity2010

    • Author(s)
      Kobayashi, T.
    • Organizer
      4^<th> ISN Special Conference on Membrane Domains in CNS physiology and pathology
    • Place of Presentation
      Erice, Italy
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PUBLICLY-21113530
  • [Presentation] Imaging lipids2009

    • Author(s)
      Kobayashi T, Abe M, Ishitsuka R, Shimada Y, Makino A, Murate M
    • Organizer
      The Fourth iCeMS International Symposium: Integrated physical/chemical biology of the cell: from genes to membrane systems
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Visualization of lipid domains2009

    • Author(s)
      Kobayashi T
    • Organizer
      50^<th> International Conference of the Bioscience of Lipids
    • Place of Presentation
      Regensburg
    • Year and Date
      2009-09-02
    • Data Source
      KAKENHI-PUBLICLY-21113530
  • [Presentation] Imaging lipids2009

    • Author(s)
      Kobayashi T
    • Organizer
      Membranes biologiques & membranes biomimetiques
    • Place of Presentation
      Lyon, France
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Imaging lipids2009

    • Author(s)
      Kobayashi T.
    • Organizer
      Membranes biologiques and membranes biomimetiques
    • Place of Presentation
      Lyon, France
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] 脂質を見ることで見えてきたもの2008

    • Author(s)
      小林俊秀
    • Organizer
      19^<th> Forum in DIJIN「細胞膜脂質のダイナミクス」
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] 脂質を見ることで見えてきたもの2008

    • Author(s)
      小林俊秀
    • Organizer
      19thフォーラム・イン・ドージン
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Imaging lipids and lipid domains2008

    • Author(s)
      Abe M, Hullin-Matsuda F, Inadome H, Ishitsuka R, Iwamoto K, Makino A, Murase K, Murate M, Senoh Y, Ueda Y, Kobayashi T
    • Organizer
      JSPS-SNSF International Seminar "Membranomics-Science and Engineering of Biomembranes and Its Mimics"
    • Place of Presentation
      Osaka, Japan
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] 脂質ラフトは存在するか?2008

    • Author(s)
      小林俊秀
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] 脂質ラフトは存在するか2008

    • Author(s)
      小林俊秀
    • Organizer
      第二十二回順天堂大学環境医学研究所セミナー
    • Place of Presentation
      浦安
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Cholesterol gradient in cell membranes2008

    • Author(s)
      Kobayashi T
    • Organizer
      The 11th International Membrane Research Forum
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Imaging lipids and lipid domains2008

    • Author(s)
      Kobayashi T
    • Organizer
      8th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
    • Place of Presentation
      Hyderabad, India
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] コレステロールを見る2008

    • Author(s)
      小林俊秀
    • Organizer
      第二回藤田神経学セミナー
    • Place of Presentation
      豊明
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Dissecting lipid nanodomains in biomembranes.2007

    • Author(s)
      Kobayashi T
    • Organizer
      2007 Asian Research Network Symposium on Nanoscience and Nanotechnology.
    • Place of Presentation
      Daejeon,Korea
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] 脂質特異的プローブを用いた細胞膜脂質の分布と動態の解析2007

    • Author(s)
      小林俊秀
    • Organizer
      第112回 日本解剖学会総会・全国学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] 細胞密度とコレステロールに依存したスフィンゴ脂質のエンドサイトーシス2007

    • Author(s)
      小林俊秀
    • Organizer
      第2回スフィンゴテラピー研究会
    • Place of Presentation
      米子
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Dissecting lipid nanodomains in biomembranes2007

    • Author(s)
      Kobayashi T
    • Organizer
      2007 Asian Research Network Symposium on Nanoscience and Nanotechnology
    • Place of Presentation
      Daejeon, Korea
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Lipid domains; Order or chaos?2007

    • Author(s)
      Kobayashi T
    • Organizer
      The 3rd Yamada Symposium on From Chaos to Cosmos: Integration in Biological Systems
    • Place of Presentation
      Hayama, Japan
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Lipid domains:Order or chaos?2007

    • Author(s)
      Kobayashi T
    • Organizer
      The 3^<rd> Yamada Symposium
    • Place of Presentation
      Hayama,Japan
    • Data Source
      KAKENHI-PROJECT-19390027
  • [Presentation] Imaging lipids and lipid domains

    • Author(s)
      Kobayashi T
    • Organizer
      2nd Mini Symposium “Protein-lipid interactions”
    • Place of Presentation
      Piran, Slovenia
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293015
  • [Presentation] Imaging lipids and lipid domains

    • Author(s)
      Kobayashi T
    • Organizer
      2nd Mini Symposium “Protein-lipid interactions”
    • Place of Presentation
      Piran, Slovenia
    • Invited
    • Data Source
      KAKENHI-PROJECT-24657143
  • [Presentation] 脂質のイメージング

    • Author(s)
      小林俊秀
    • Organizer
      第1回JFAS講演会
    • Place of Presentation
      秋葉原
    • Invited
    • Data Source
      KAKENHI-PROJECT-25293015
  • []

  • 1.  ISHITSUKA Reiko (60342747)
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  • 2.  MURATE Motohide (30311369)
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  • 15.  清水 善久 (80344042)
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    # of Collaborated Products: 0 results
  • 19.  大西 哲生 (80373281)
    # of Collaborated Projects: 1 results
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  • 21.  西村 慎一
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    # of Collaborated Products: 1 results
  • 22.  向後 寛
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  • 23.  佐藤 栄人
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