yamamoto satoshi 山本悟史

… Alternative Names

山本悟史ヤマモトサトシ

YAMAMOTO Satoshi 山本悟史

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Researcher Number	60220464
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023: 兵庫医科大学, 薬学部, 教授 2007 – 2018: Hyogo University of Health Sciences, 薬学部, 教授 2002 – 2006: 兵庫医科大学, 医学部, 助教授 1997 – 2001: 久留米大学, 医学部, 助手 1993 – 1994: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 神経・脳内生理学 / Pain science / Basic Section 55050:Anesthesiology-related / 疼痛学 / Neurophysiology and muscle physiology Except Principal Investigator Anesthesiology/Resuscitation studies / General physiology / Pain science / 神経・脳内生理学 / Neurochemistry/Neuropharmacology / Cerebral neurosurgery
Keywords	Principal Investigator 脊髄後根神経節 / 熱 / K+チャネル / 神経因性疼痛 / Brain ischemia / 脳虚血 / Kチャネル / 神経障害性疼痛 / パッチクランプ / アストロサイト … More / グリア細胞 / アドレナリン受容体 / 脊髄後根神経 / DRG神経細胞 / 熱感受性Kチャネル / プロスタグランジンE1 / プロスタグランジン受容体 / プロスタグランジン / 神経科学 / TRPV1受容体 / 神経傷害性疼痛 / セロトニン受容体 / セロトニン / Glutamate receptors / Glutamate / Membrane current / Patch-clamp / Astrocyte / Glial cell / グルタミン酸受容体 / グルタミン酸 / 膜電流 / Hippocampal CA1 pyramidal neuron / Necrosis / Apoptosis / 海馬CA1細胞 / 海馬CA1錐体細胞 / ネクローシス / アポトーシス / Patch clamp / Na, K-pump / Culture cell / Astrocytes / Glia cell / Na,K-pump / 培養細胞 / ATP受容体 / ATP / K^+チャネル / アドレナリン受容体 / 交感神経 / イオンチャネル / 感覚系神経生理学 … More Except Principal Investigator 脳虚血 / PKA / Prostaglandin / Lipoxygenase / Cyclooxygenase / forebrain ischemia / rats / Ischemic preconditioning / Electromagnetic Fields / 細胞内カルシウム / 海馬スライス実験的脳虚血 / ラット前脳虚血モデル / 経頭蓋磁気刺激 / 脳虚血耐性 / Brain ischemia / Hippocampal CA 1 neurons / 細胞内情報伝達系 / 海馬錐体細胞 / Pain / TRPA1 / AMPK / Adenosine A_<2a> receptor / Adenosine / Vesicular transport / Acetylcholine / Striatum / Astrocyte / アデノシンA2a受容体 / アデノシン / 小胞輸送 / アセチルコリン / 線条体 / 神経膠細胞 / ラット / 局所脳虚血モデル / 前脳虚血モデル / 電気けいれん療法 / c-FOS / ラット局所脳虚血モデル / 電気痙攣療法 / 海馬スライス実験的脳虚血モデル / 磁気刺激 / Intracellular signal transduction system / Thromboxane A2 / Hoppocampus / Central nervous system / アラキドン酸 / Protein kinase C / Calmodulin / Protein kinase A / Thronboxane A_2 / Thronboxane A2 / 海馬 / 中枢神経 / Synaptic responses / Ca^<2+> antagonists / Cell swelling / Small blebs / Rapid depolarization / Necrosis / glutamate / superoxide dismutase / NO scavengers / NO / 低温環境 / biocytin / 細胞膨化 / CA^<2+>蓄積 / small blebs / NO synthase阻害薬 / Ca^<2+>拮抗薬 / 細胞内Ca^<2+>蓄積 / シナプス応答 / 急峻脱分極電位 / ネクローシス / C kinase / Calmodulin Kinase II / Internal Ca^<2+> concentration / Signal transduction system / ATP-sensitive K^+ channels / Ca^<2+> -dependent K^+ channels / Anoxic hyperpolarization / Fura-2 / Ckinase / Calmoduline Kinase II / Tolbutamide / Glybenclamide / Nicorandil / Diazoxide / 海馬錘体細胞 / 低酸素誘起過分極電位 / 細胞内Ca濃度 / C-kinase / Catmodulin kinaseII / ATP依存性Kチャネル / Ca依存性Kチャネル / 低酸素負荷 / Ets2 / 遺伝子治療 / 浸潤 / グリオーマ / 長期増強現象 / シナプス可塑性 / 海馬神経伝達 / リサイクリング / O-GlcNAc化 / GluR1 / AMPA受容体 / 神経伝達物質受容体 / 細胞内記録 / 海馬錐体神経細胞 / 局所麻酔薬 / Ca電流 / whole cell patch recording / 脊髄神経節細胞 Less

末梢神経障害性疼痛に対するプロスタグランジンE1製剤の新たな作用機序Principal Investigator
- Principal Investigator
  
  山本悟史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hyogo Medical University
Study of a role of serotonin on a novel K channel in neuropathic pain.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Hyogo University of Health Sciences
pain modulation by AMP kinase through TRP channels and its molecular mechanism
- Principal Investigator
  
  DAI YI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Hyogo University of Health Sciences
Study of a role of ATP on a novel K+ channel in neuropathic pain.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Hyogo University of Health Sciences
Study of a role of sympathetic nerves on a novel K+ channel in neuropathic pain.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Hyogo University of Health Sciences
Study of a novel K^+ channel in generation of neuropathic painPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Hyogo University of Health Sciences
Ets2を標的遺伝子とした脳腫瘍浸潤抑制法の確立
- Principal Investigator
  
  藤川浩一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Hyogo College of Medicine
神経伝達物質リサイクリングにおけるO-G1cNAc化分子制御機構の解明
- Principal Investigator
  
  NISHIZAKI Tomoyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Hyogo Medical University
Vesicular Acetylcholine Release from Astrocytes by Adenosine Signal
- Principal Investigator
  
  YAJIMA Yukio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hyogo College of Medicine
Study of glial cell function during brain ischemiaPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Hyogo College of Medicine
The ischemic tolerance induced by electromagnetic field exposure.
- Principal Investigator
  
  HARADA Hideki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kurume University
In vitro ischemic neuronal death and the intracellular signal transduction systems
- Principal Investigator
  
  TANAKA Eiichiri
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Kurume University
Can apoptosis-suppressing proteins inhibit neuronal necrosis induced by brain ischemia?Principal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Kurume University School of Medicine
The ischemic tolerance induced by transcranial magnetic stimulation
- Principal Investigator
  
  HARADA Hideki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kurume University, School of Medicine
Membrane dysfunction induced by in vitro ischemia in rat hippocampal CA1 pyramidal neurons
- Principal Investigator
  
  HIGASHI Hideho
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kurume University
Role of glia cell during brain ischemiaPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Satoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Kurume University
脊椎麻酔は下行大動脈遮断に伴う脊髄の虚血性障害を緩和できるか
- Principal Investigator
  
  杉山和英
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kurume University
Mechanisms for hypoxia-induced hyperpolarization in the rat hippocampal CA 1 neurons in vitro.
- Principal Investigator
  
  HIGASHI Hideho
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kurume University

All 2018 2017 2016 2015 2014 2013 2011 2009 2007 Other

All Journal Article Presentation

[Journal Article] Negative Regulation of TRPA1 by AMPK in Primary Sensory Neurons as a Potential Mechanism of Painful Diabetic Neuropathy.2018
- Author(s)
  Wang S, Kobayashi K, Kogure Y, Yamanaka H, Yamamoto S, Yagi H, Noguchi K, Dai Y
- Journal Title
  
  Diabetes
  
  Volume: 67(1) Issue: 1 Pages: 98-109
- DOI
  10.2337/db17-0503
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09004, KAKENHI-PROJECT-17K09048, KAKENHI-PROJECT-17K19736, KAKENHI-PROJECT-17H04113
[Journal Article] Elevated H2 O2 levels in TNBS-induced colitis rats contributes to visceral hyperalgesia through interaction with the TRPA1 cation channel.2016
- Author(s)
  Kogure Y, Wang S, Tanaka KI, Hao Y, Yamamoto S, Nishiyama N, Noguchi K, Dai Y.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 未定 Issue: 6 Pages: 1147-1153
- DOI
  10.1111/jgh.13226
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460713, KAKENHI-PROJECT-25290016, KAKENHI-PROJECT-15K15205, KAKENHI-PROJECT-16K09004
[Journal Article] Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels.2016
- Author(s)
  Iwaoka E, Wang S, Matsuyoshi N, Kogure Y, Aoki S, Yamamoto S, Noguchi K, Dai Y.
- Journal Title
  
  J Nat Med
  
  Volume: 70 Issue: 1 Pages: 1-7
- DOI
  10.1007/s11418-015-0929-1
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460713, KAKENHI-PROJECT-15K15205, KAKENHI-PROJECT-15K21538, KAKENHI-PROJECT-23510284, KAKENHI-PROJECT-25290016
[Journal Article] Partial Activation and Inhibition of TRPV1 Channels by Evodiamine and Rutaecarpine, Two Major Components of the Fruits of Evodia rutaecarpa.2016
- Author(s)
  Wang S, Yamamoto S, Kogure Y, Zhang W, Noguchi K, Dai Y
- Journal Title
  
  J Nat Prod.
  
  Volume: 79 Issue: 5 Pages: 1225-1230
- DOI
  10.1021/acs.jnatprod.5b00599
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460713, KAKENHI-PROJECT-15K15205, KAKENHI-PROJECT-15K21538, KAKENHI-PROJECT-16K09004
[Journal Article] Modulation of TRP channels by resveratrol and other stilbenoids.2013
- Author(s)
  Yu L, Wang S, Kogure Y, Yamamoto S, Noguchi K, Dai Y.
- Journal Title
  
  Mol Pain.
  
  Volume: Vol.9 Pages: 3-13
- DOI
  10.1186/1744-8069-9-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600013, KAKENHI-PROJECT-23590730, KAKENHI-PROJECT-24659688, KAKENHI-PROJECT-25290016
[Journal Article] Etodolac activates and desensitizes transient receptor potential ankyrin 12013
- Author(s)
  Wang S, Dai Y, Kogure Y, Yamamoto S, Zhang W, Noguchi K
- Journal Title
  
  J Neurosci Res
  
  Volume: 91(12) Issue: 12 Pages: 1591-8
- DOI
  10.1002/jnr.23274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590730, KAKENHI-PROJECT-24659688, KAKENHI-PROJECT-25290016, KAKENHI-PROJECT-25460731
[Journal Article] Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin.2011
- Author(s)
  Yoshida N, Kobayashi K, Yu L, Wang S, Na R, Yamamoto S, Noguchi K, Dai Y.
- Journal Title
  
  Mol Pain
  
  Volume: 7 Pages: 41-41
- DOI
  10.1186/1744-8069-7-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300115, KAKENHI-PROJECT-22600013, KAKENHI-PUBLICLY-23116517, KAKENHI-PROJECT-23590730
[Journal Article] Dual regulation of heat-activated K^+ channel in rat DRG neurons via alpha(1)and beta adrenergic receptors2009
- Author(s)
  Yamamoto S, 他
- Journal Title
  
  Life Sci. Vol.85
  
  Pages: 167-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500353
[Journal Article] Dual regulation of heat-activated K+ channel in rat DRG neurons via alpha(1) and beta adrenergic receptors2009
- Author(s)
  Yamamoto S, Kanno T, Yamada K, Yasuda Y, Nishizaki T
- Journal Title
  
  Life Sci Vol.85
  
  Pages: 167-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500353
[Journal Article] Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain2007
- Author(s)
  Dai, Y., Yamamoto, S., 他
- Journal Title
  
  J.Clin.Invest. 117
  
  Pages: 1979-1987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500353
[Journal Article] Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain2007
- Author(s)
  Dai Y, Wang S, Tominaga M, Yamamoto S, Fikuoka T, Higashi T, Kobayashi K, Obata K, Yamanaka H, Noguchi K
- Journal Title
  
  J Clin Invest
  
  Pages: 1979-1987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500353
[Presentation] 一次知覚神経におけるAMPキナーゼによるTRPA1膜発現の制御2017
- Author(s)
  王勝蘭、小林希実子、小暮洋子、山中博樹、山本悟史、八木秀司、野口光一、戴毅
- Organizer
  第39回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K09004
[Presentation] TRPA1 is involved in vincristine induced cold allodynia.2016
- Author(s)
  Wang S., Kojima Y., Kogure Y, Yamamoto S, Noguchi K, Dai Y
- Organizer
  16th world congress on pain
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-09-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460713
[Presentation] Modulation of TRPA1 activation by AMP activated protein kinase2016
- Author(s)
  Wang S, Kobayashi K, Yamanaka H, Yamamoto S, Kogure Y, Noguchi K, Dai Y
- Organizer
  46th annual meeting of neuroscience 2016
- Place of Presentation
  San Diego Convention Center (San Diego, CA, U.S.A.)
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460713
[Presentation] Partial activation and inhibition of TRPV1 channels by evodiamine and rutaecarpine, two major components of evodiae fructus.2016
- Author(s)
  Wang S, Yamamoto S, Kogure Y, Zhang W, Noguchi K, Dai Y
- Organizer
  The 18th International congress of oriental medicine 2016
- Place of Presentation
  Okinawa convention center　(Ginowan, Okinawa, Japan)
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460713
[Presentation] エボジアミンはTRPV1チャネルのパーシャルアゴニストである2015
- Author(s)
  王勝蘭, 山本悟史, 野口光一, 戴毅
- Organizer
  第37回日本疼痛学会
- Place of Presentation
  市民会館崇城大学ホール（熊本市民会館）（熊本県熊本市）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26460713
[Presentation] Evodiamine activates transient receptor potential V1 as a partial agonist2014
- Author(s)
  WANG S., IWAOKA E., KOGURE Y., AOKI S., YAMAMOTO S., NOGUCHI K., DAI Y.
- Organizer
  44th annual meeting of neuroscience 2014
- Place of Presentation
  Washington, D.C. , USA
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-26460713
[Presentation] Practical training in electrophysiology of the heart2009
- Author(s)
  Kogure Y, Yamamoto S
- Organizer
  IUPS teaching workshop
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-19500353
[Presentation] Practical training in electrophysiology of the heart2009
- Author(s)
  Kogure Y., Yamamoto S.
- Organizer
  IUPS teaching workshop
- Place of Presentation
  Nichii-gakkan, Kobe
- Data Source
  KAKENHI-PROJECT-19500353
[Presentation] Evodiamine activates transient receptor potential V1 as a partial agonist.
- Author(s)
  Wang S, Iwaoka E, Kogure Y, Aoki S., Yamamoto S., Noguchi K., DAI Y
- Organizer
  The 44th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington D.C., USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460731

1. NISHIZAKI Tomoyuki (00221474)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. NAGATA Tetsu (60131588)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. DAI Tsuyoshi (20330441)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
4. HIGASHI Hideho (10098907)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KOGURE Yoko (60548684)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
6. YAMAMOTO Hideyuki (70373529)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
7. TANAKA Kohichi (30274848)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. TANAKA Eiichiri (80188284)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HARADA Hideki (30198923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MATSUDA Tsuruo (60258598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 藤川浩一 (40312136)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 三島康典 (30258470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. INOKUCHI Hiroe (10080558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAJIMA Yukio (10068489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Noguchi Koichi (10212127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
16. Wang Shenglan (50714359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
17. 杉山和英 (80140721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大石一男 (70203700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 無敵剛介 (60080917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 長井薫 (20340953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

yamamoto satoshi 山本 悟史

山本 悟史 ヤマモト サトシ

YAMAMOTO Satoshi 山本 悟史

Research Projects

Research Products

Co-Researchers

末梢神経障害性疼痛に対するプロスタグランジンE1製剤の新たな作用機序Principal Investigator

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Study of a role of serotonin on a novel K channel in neuropathic pain.Principal Investigator

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Principal Investigator

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Study of a role of ATP on a novel K+ channel in neuropathic pain.Principal Investigator

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Research Institution

Study of a role of sympathetic nerves on a novel K+ channel in neuropathic pain.Principal Investigator

Principal Investigator

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Study of a novel K^+ channel in generation of neuropathic painPrincipal Investigator

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Principal Investigator

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Study of glial cell function during brain ischemiaPrincipal Investigator

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Can apoptosis-suppressing proteins inhibit neuronal necrosis induced by brain ischemia?Principal Investigator

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yamamoto satoshi 山本悟史

山本悟史ヤマモトサトシ

YAMAMOTO Satoshi 山本悟史