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Shibata Mamoru  柴田 護

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… Alternative Names

SHIBATA Mamoru  柴田 護

柴田 護  シバタ マモル

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Researcher Number 60286466
Other IDs
Affiliation (Current) 2022: 東京歯科大学, 歯学部, 教授
2022: 慶應義塾大学, 医学部(信濃町), 客員教授
Affiliation (based on the past Project Information) *help 2020: 慶應義塾大学, 医学部(信濃町), 客員教授
2016 – 2019: 慶應義塾大学, 医学部(信濃町), 講師
2017: 慶應義塾大学, 医学部, 講師
2010 – 2015: 慶應義塾大学, 医学部, 講師
2000 – 2001: 慶應義塾大学, 医学部, 助手
1997 – 1998: 慶應義塾大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Neurology / Pain science / Basic Section 51030:Pathophysiologic neuroscience-related
Except Principal Investigator
Pain science / Neurology / Neurology
Keywords
Principal Investigator
三叉神経節ニューロン / 片頭痛 / パーキンソン病 / 遺伝子治療 / レトロウィルス / neural stem cell / レトロウイルス / ミトコンドリア / オートファジー / ミトファジー … More / 皮質拡延性抑制 / TRPV1 / カプサイシン / 神経修復機構 / 三叉神経節 / リソソーム / アナンダマイド / 神経障害性疼痛 / HMGB1 / ミクログリア / Toll-like receptor / 侵害性刺激 / 多系統萎縮症 / 皮質基底核変性症 / heat shock protein / タウ / cyclin-dependent kinase / p38 MAP Kinase / カスパーゼ / 小胞体ストレス / AT8 / p38 / Cdk5 / p35 / p25 / αB crystallin / multiple system atrophy / corticobasal degeneration / heat shock ploteins / tau / cyclin-dependent kinare / p38 MAP kinase / caspase / endoplasmic reticulum stress / 三叉神経 / CGRP / 感作 / 光過敏 / 活動性低下 / 生活の質 / 核酸医薬 … More
Except Principal Investigator
片頭痛 / 皮質拡延性抑制 / 三叉神経節 / 三叉神経 / CGRP / TRPV1 / MTT / Alamar Blue / HMGB1 / アポトーシス / 大脳皮質性拡延性抑制 / 三叉神経血管系 / TRPV1受容体 / ERK / 硬膜 / 神経原性炎症 / 翼口蓋神経節 / アストロサイト / ニューロン / グルコース / グリコーゲン / ピルビン酸 / 乳酸 / 虚血 / TCA回路 / Naイオン / オリゴデンドロサイト / LDH / SBFI / ミトコンドリア / ASTROCYTE / NEURON / GLUCOSE / GLYCOGEN / PYRUVATE / LACTATE / a片頭痛 / 女性ホルモン / 光過敏 / エストロゲン / プロゲステロン / 性周期 / 神経科学 Less
  • Research Projects

    (8 results)
  • Research Products

    (94 results)
  • Co-Researchers

    (22 People)
  •  Elucidation of the role of CGRP in migraine pathophysiology and application of oligonucleotide therapeutics to migraine treatmentPrincipal Investigator

    • Principal Investigator
      柴田 護
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Keio University
  •  慢性疼痛が皮質拡延性に及ぼす影響-片頭痛の病態解析

    • Principal Investigator
      清水 利彦
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pain science
    • Research Institution
      Keio University
  •  Analysis of pain disease model-associated mitochondrial abnormalities in primary sensory neuronsPrincipal Investigator

    • Principal Investigator
      Shibata Mamoru
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pain science
    • Research Institution
      Keio University
  •  Trigeminal contribution to the neurogenic inflammation in the dura mater

    • Principal Investigator
      Shimizu Toshihiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pain science
    • Research Institution
      Keio University
  •  Research on migraine pathophysiology related to cortical spreading depression

    • Principal Investigator
      SUZUKI Norihiro
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Keio University
  •  Clinical and basic investigation on the pathogenesis of multiple system atrophyPrincipal Investigator

    • Principal Investigator
      HAMADA Junichi, 柴田 護
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Keio University
  •  Roles of astroglial energy metabolism in ischemic neuronal cell damage: an implication for the treatment of cerebral ischemia

    • Principal Investigator
      TAKEDA Hidetaka, 福内 靖男
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Keio University
  •  遺伝子導入neural stem cellを用いたパーキンソン病モデルの移植治療Principal Investigator

    • Principal Investigator
      柴田 護
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurology
    • Research Institution
      Keio University

All 2021 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] 薬物乱用頭痛,慢性連日性頭痛.アクチュアル脳・神経疾患の臨床.識る診る治す頭痛のすべて(鈴木則宏編集)2011

    • Author(s)
      柴田護
    • Publisher
      中山書店,東京
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Book] パーキンソン病の頭痛,パーキンソン病臨床の諸問題2(山本光利編)2011

    • Author(s)
      柴田護
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Book] 慢性頭痛/片頭痛 ポケット判 診療ガイドラインUP-TO-DATE.(門脇孝、小室一成、宮地良樹監修)2010

    • Author(s)
      柴田護、鈴木則宏
    • Publisher
      メディカルレビュー社、大阪・東京
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Book] これでわかる頭痛診療-頭痛外来でのノウハウとコツ2010

    • Author(s)
      鈴木則宏、清水利彦、柴田護
    • Publisher
      南江堂、東京
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] Protracted hypomobility in the absence of trigeminal sensitization after cortical spreading depolarization: Relevance to migraine postdrome2021

    • Author(s)
      Shibata Mamoru、Kitagawa Satoshi、Tang Chunghua、Unekawa Miyuki、Kayama Yohei、Shimizu Toshihiko、Nakahara Jin、Suzuki Norihiro
    • Journal Title

      Neuroscience Research

      Volume: -

    • DOI

      10.1016/j.neures.2021.03.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Journal Article] Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant2020

    • Author(s)
      Tang Chunhua、Unekawa Miyuki、Kitagawa Satoshi、Takizawa Tsubasa、Kayama Yohei、Nakahara Jin、Shibata Mamoru
    • Journal Title

      Scientific Reports

      Volume: 10

    • DOI

      10.1038/s41598-020-67948-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Journal Article] [123I]-IMP single-photon emission computed tomography imaging in visual snow syndrome: A case series2020

    • Author(s)
      Shibata Mamoru、Tsutsumi Kei、Iwabuchi Yu、Kameyama Masashi、Takizawa Tsubasa、Nakahara Tadaki、Fujiwara Hirokazu、Jinzaki Masahiro、Nakahara Jin、Dodick David W
    • Journal Title

      Cephalalgia

      Volume: 40 Pages: 1671-1675

    • DOI

      10.1177/0333102420950454

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07849, KAKENHI-PROJECT-18K07488
  • [Journal Article] Resilience to capsaicin-induced mitochondrial damage in trigeminal ganglion neurons2020

    • Author(s)
      Shibata Mamoru、Kayama Yohei、Takizawa Tsubasa、Ibata Keiji、Shimizu Toshihiko、Yuzaki Michisuke、Suzuki Norihiro、Nakahara Jin
    • Journal Title

      Molecular Pain

      Volume: 16

    • DOI

      10.1177/1744806920960856

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Journal Article] Implications of Transient Receptor Potential Cation Channels in Migraine Pathophysiology2020

    • Author(s)
      Shibata Mamoru、Tang Chunhua
    • Journal Title

      Neuroscience Bulletin

      Volume: 37 Pages: 103-116

    • DOI

      10.1007/s12264-020-00569-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Journal Article] Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 22020

    • Author(s)
      Tang Chunhua、Unekawa Miyuki、Shibata Mamoru、Tomita Yutaka、Izawa Yoshikane、Sugimoto Hiroki、Ikeda Keiko、Kawakami Kiyoshi、Suzuki Norihiro、Nakahara Jin
    • Journal Title

      Cephalalgia

      Volume: 40 Pages: 1177-1190

    • DOI

      10.1177/0333102420929028

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07849, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-19K17018
  • [Journal Article] Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology.2018

    • Author(s)
      Kayama Y, Shibata M, Takizawa T, Ibata K, Shimizu T, Ebine T, Toriumi H, Yuzaki M, Suzuki N.
    • Journal Title

      Cephalalgia

      Volume: 38(5) Pages: 833-845

    • DOI

      10.1177/0333102417712719

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06461, KAKENHI-PROJECT-26460706, KAKENHI-PROJECT-15H05772
  • [Journal Article] Signaling Pathways Relevant to Nerve Growth Factor-induced Upregulation of Transient Receptor Potential M8 Expression.2017

    • Author(s)
      Kayama Y, Shibata M, Takizawa T, Ibata K, Nakahara J, Shimizu T, Toriumi H, Yuzaki M, Suzuki N.
    • Journal Title

      Neuroscience

      Volume: 367 Pages: 178-188

    • DOI

      10.1016/j.neuroscience.2017.10.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] High-mobility group box 1 (HMGB1) is an important mediator of microglial activation induced by cortical spreading depression.2017

    • Author(s)
      Takizawa T., Shibata M., Kayama Y., Shimizu T., Toriumi H., Ebine T., Unekawa M., Koh A., Yoshimura A., Suzuki N.
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 37 Pages: 890-901

    • DOI

      10.1177/0271678x16647398

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350981, KAKENHI-PROJECT-26460706
  • [Journal Article] Exploring the role of microglia in cortical spreading depression in neurological disease.2017

    • Author(s)
      Shibata M, Suzuki N.
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 37 Pages: 1182-1191

    • DOI

      10.1177/0271678x17690537

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] Possible Involvement of Hypotension in Postprandial Headache: A Case Series.2017

    • Author(s)
      Takizawa T, Shibata M, Hiraide T, Seki M, Takahashi S, Suzuki N.
    • Journal Title

      Headache

      Volume: 57 Pages: 1443-1448

    • DOI

      10.1111/head.13136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] How have animal studies contributed to the development of migraine research?2016

    • Author(s)
      柴田 護
    • Journal Title

      日本頭痛学会誌

      Volume: 43 Pages: 61-64

    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] Repetitive trigeminal nociceptive stimulation in rats increases their susceptibility to cortical spreading depression.2016

    • Author(s)
      Toriumi H, Shimizu T, Ebine T, Takizawa T, Kayama Y, Koh A, Shibata M, Suzuki N
    • Journal Title

      Neurosci Res

      Volume: 106 Pages: 74-78

    • DOI

      10.1016/j.neures.2015.12.010

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460726
  • [Journal Article] Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice.2016

    • Author(s)
      Takizawa T, Shibata M, Kayama Y, Toriumi H, Ebine T, Koh A, Shimizu T, Suzuki N
    • Journal Title

      Cephalalgia

      Volume: 印刷中 Pages: 44-52

    • DOI

      10.1177/0333102415580100

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-26460706, KAKENHI-PROJECT-25460726
  • [Journal Article] Alterations in the threshold of the potassium concentration to evoke cortical spreading depression during the natural estrous cycle in mice.2016

    • Author(s)
      Taeko Ebine, Haruki Toriumi, Toshihiko Shimizu, Miyuki Unekawa, Tsubasa Takizawa, Yohei Kayama, Mamoru Shibata, Norihiro Suzuki
    • Journal Title

      Neurosci. Res.

      Volume: 112 Pages: 57-62

    • DOI

      10.1016/j.neures.2016.06.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K08996, KAKENHI-PROJECT-26350981
  • [Journal Article] Adult-onset recurrent painful ophthalmoplegic neuropathy displaying atypical oculomotor nerve gadolinium-enhancement pattern in the orbit and cavernous sinus.2016

    • Author(s)
      Takizawa T, Shibata M*, Fujiwara H, Shimizu T, Momoshima S, Suzuki N.
    • Journal Title

      Cephalalgia

      Volume: 36 Pages: 199-200

    • DOI

      10.1177/0333102415583987

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] ミクログリアと皮質拡延性抑制.2016

    • Author(s)
      柴田 護.
    • Journal Title

      Annual Review神経2016

      Volume: - Pages: 63-68

    • Open Access
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] Clinical utility of triptans in the management of headache attributed to dural arteriovenous fistula involving the cavernous sinus.2015

    • Author(s)
      39.Osaka M, Shibata M#, Oki K, Yamada S, Kufukibara K, Akiyama T, Yoshida K, Suzuki N. (#corresponding author)
    • Journal Title

      J Neurol Sci

      Volume: 349 Pages: 260-261

    • DOI

      10.1016/j.jns.2015.01.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] Intracranial hemorrhage due to venous thrombosis of developmental venous anomaly during pregnancy.2015

    • Author(s)
      Seki M, Shibata M, Itoh Y, Suzuki N.
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] 薬剤の使用過多による頭痛 (薬物乱用頭痛, MOH)の病態生理と診断.2014

    • Author(s)
      柴田 護
    • Journal Title

      神経内科

      Volume: 81 Pages: 417-422

    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] 片頭痛のメカニズム2014

    • Author(s)
      柴田 護
    • Journal Title

      日本頭痛学会誌

      Volume: 41 Pages: 26-29

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] 専門医部会 シリーズ: 患者の言葉・身体所見を読み解く 頭痛~病歴と画像診断から診断を考える~.2014

    • Author(s)
      柴田 護
    • Journal Title

      日本内科学会雑誌

      Volume: 103 Pages: 2841-2844

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Journal Article] 片頭痛の予後はどうか?2013

    • Author(s)
      柴田 護
    • Journal Title

      日本頭痛学会誌

      Volume: 40 Pages: 30-31

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] Activation of extracellular signal-regulated kinase in the trigeminal ganglion following both treatment of the dura mater with capsaicin and cortical spreading depression.2013

    • Author(s)
      Iwashita T, Shimizu T, Shibata M, Toriumi H, Ebine T, Funakubo M, Suzuki N.
    • Journal Title

      Neurosci Res.

      Volume: 77 Pages: 110-119

    • DOI

      10.1016/j.neures.2013.08.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-24590732
  • [Journal Article] 片頭痛慢性化の病態生理2013

    • Author(s)
      柴田 護
    • Journal Title

      臨床神経学

      Volume: 53 Pages: 1220-1222

    • NAID

      130004505393

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.2013

    • Author(s)
      Sato H, Shibata M, Shimizu T, Shibata S, Haruki T, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T. Okano H. Suzuki N
    • Journal Title

      Neuroscience.

      Volume: 248 Pages: 345-348

    • DOI

      10.1016/j.neuroscience.2013.06.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J00978, KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24590732
  • [Journal Article] 片頭痛慢性化のメカニズム2012

    • Author(s)
      柴田 護
    • Journal Title

      臨床神経学

      Volume: 52 Pages: 1012-1013

    • NAID

      130004505041

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] Migraine Future Research Perspectives日本の最新の研究からTRPV1介在性の自食作用感覚システム再構築との関連2011

    • Author(s)
      柴田護
    • Journal Title

      Headache Clinical & Science

      Volume: 2(解説) Pages: 57-58

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] 片頭痛の病態研究および治療に関する最近の知見2011

    • Author(s)
      清水利彦、柴田護、鈴木則宏
    • Journal Title

      臨床神経

      Volume: 51 Pages: 103-109

    • NAID

      10031163984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] TRPV1発現量に応じたカプサイシン刺激時の細胞死誘導機構片頭痛慢性化への関与2011

    • Author(s)
      舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 鈴木則宏
    • Journal Title

      日本頭痛学会誌

      Volume: 38 Pages: 21-24

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] Developmental and circulatory profile of the diploic veins2011

    • Author(s)
      Toriumi H, Shimizu T, Shibata M, Unekawa M, Tomita Y, Tomita M, Suzuki N
    • Journal Title

      Microvascular Research

      Volume: 81 Pages: 97-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Journal Article] テーラーメード治療のための治療薬の選択と使用法ガイドライン頭痛(片頭痛,緊張型頭痛)2010

    • Author(s)
      柴田護
    • Journal Title

      Medical Practice

      Volume: Vol.27 臨時増刊号 Pages: 194-200

    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Gepants and Lasmiditan: novel players in acute migraine treatment.2020

    • Author(s)
      柴田 護
    • Organizer
      第61回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Presentation] 片頭痛の病態2020

    • Author(s)
      柴田 護
    • Organizer
      第25回日本口腔顔面痛学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Presentation] 前庭性片頭痛 (片頭痛関連めまい)の病態と治療2020

    • Author(s)
      柴田 護
    • Organizer
      第61回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Presentation] 経口CGRP拮抗薬gepantの開発状況2020

    • Author(s)
      柴田 護
    • Organizer
      第38回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Presentation] 光と片頭痛ー基礎研究から臨床研究へ 皮質拡延性抑制による行動変容に対するCGRP受容体阻害の影響―明暗所での比較2020

    • Author(s)
      柴田 護
    • Organizer
      第48回日本頭痛学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Presentation] 片頭痛の薬物治療2020

    • Author(s)
      柴田 護
    • Organizer
      第38回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07849
  • [Presentation] Development of photophobia-like behaviors after cortical spreading depression in mice2018

    • Author(s)
      Kitagawa S,Shibata M, Unekawa M, Kayama Y, Hua TC , Shimizu T,Suzuki N, Nakahara J
    • Organizer
      第46回日本頭痛学会総会
    • Data Source
      KAKENHI-PROJECT-16K08996
  • [Presentation] Facial TRPM8 stimulation ameliorates thermal hyperalgesia in a mouse migraine model.2017

    • Author(s)
      Kayama S, Shibata M, Takizawa T, Shimizu T, Toriumi H, Ebine T, Suzuki N.
    • Organizer
      IHC2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Cortical spreading depression alters the progranulin expression in cortical neurons.2017

    • Author(s)
      Kitagawa S, Takizawa T, Kayama Y, Toriumi H, Shimizu T, Shibata M, Suzuki N.
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] 片頭痛治療のすべて 病態から見た新しい治療の展望. 片頭痛の新しい治療薬.2017

    • Author(s)
      柴田 護
    • Organizer
      第35回日本神経治療学会総会.
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Animal models of migraine: Trigeminovascular system.2017

    • Author(s)
      Shibata M
    • Organizer
      第45回日本頭痛学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] 頭痛の病態に関わるHotな分子たち. PACAPとCGRP.2017

    • Author(s)
      Shibata M
    • Organizer
      第45回日本頭痛学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Symposium 3: New therapeutic horizons for migraine. Introduction to novel migraine therapies on the horizon.2016

    • Author(s)
      Shibata M.
    • Organizer
      第44回日本頭痛学会総会
    • Place of Presentation
      Westin都ホテル京都 (京都府京都市)
    • Year and Date
      2016-10-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Temporal profiles of TRPM8 and TRPV1 expression in the trigeminal ganglion neurons after CFA-induced inflammation.2016

    • Author(s)
      Kayama Y, Shibata M, Takizawa T, Shimizu T, Toriumi H, Ebine T, Suzuki N.
    • Organizer
      EHMTIC2016
    • Place of Presentation
      Glasgow (Scotland)
    • Year and Date
      2016-09-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] HMGB1 is an important mediator of multiple CSD-induced microalial activation in the cerebral cortex.2016

    • Author(s)
      Shibata M.
    • Organizer
      The 6th Asian Regional Conference for Headache
    • Place of Presentation
      Seoul (South Korea)
    • Year and Date
      2016-10-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] なおる神経内科「片頭痛の現在・過去・未来」CGRP拮抗薬.2016

    • Author(s)
      柴田 護.
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸国際会議場 (兵庫県神戸市)
    • Year and Date
      2016-05-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Distribution of the calcitonin gene-related peptide receptors in the sphenopalatine ganglion of rat.2015

    • Author(s)
      Koh A, Shimizu T, Shibata M, Takizawa T, Kayama Y, Ebine T, Toriumi H, Suzuki N
    • Organizer
      17th Congress of the International Headache Society 2015 (IHC2015)
    • Place of Presentation
      Valencia, Spain
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460726
  • [Presentation] 慢性片頭痛と反復性片頭痛はどう違うか?2015

    • Author(s)
      柴田 護.
    • Organizer
      第43回日本頭痛学会総会
    • Place of Presentation
      京王プラザホテル (東京新宿区)
    • Year and Date
      2015-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Mechanism of cortical microglial activation after cortical spreading depression.2015

    • Author(s)
      Shibata M.
    • Organizer
      Pan-Asian/Pan-American Program, AHS57th Annual Scientific Meeting.
    • Place of Presentation
      Grand Hyatt Washington, Washington DC. (USA)
    • Year and Date
      2015-06-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Microglial activation by multiple inductions of cortical spreading depression.2015

    • Author(s)
      Takizawa T, Shibata M, Kayama Y, Shimizu T, Toriumi H, Ebine T, Koh A, Suzuki N.
    • Organizer
      Congress of the International Headache Society 2015 (IHC2015)
    • Place of Presentation
      Valencia, Spain
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460726
  • [Presentation] Microglial activation by multiple inductions of cortical spreading depression.2015

    • Author(s)
      Takizawa T, Shibata M, Kayama Y, Shimizu T, Toriumi H, Ebine T, Koh A, Suzuki N.
    • Organizer
      17th Congress of the International Headache Society 2015
    • Place of Presentation
      Valencia, Spain
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460726
  • [Presentation] How have animal studoes contributed to the elucidation of migraine pathophysiology?2015

    • Author(s)
      Shibata M.
    • Organizer
      第43回日本頭痛学会総会
    • Place of Presentation
      京王プラザホテル (東京新宿区)
    • Year and Date
      2015-11-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] 頭痛のanatomy2014

    • Author(s)
      柴田 護
    • Organizer
      Headache Master School Japan Osaka
    • Place of Presentation
      大阪 吉本ビル
    • Year and Date
      2014-07-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] 片頭痛の病態生理2014

    • Author(s)
      柴田 護
    • Organizer
      Headache Master School Japan Tokyo
    • Place of Presentation
      東京 都市センター
    • Year and Date
      2014-09-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] 片頭痛の新たな主役たち 片頭痛慢性化2014

    • Author(s)
      柴田 護
    • Organizer
      第42回日本頭痛学会総会
    • Place of Presentation
      山口県下関市海峡メッセ
    • Year and Date
      2014-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] TACsの治療2014

    • Author(s)
      柴田 護
    • Organizer
      Headache Master School Japan Osaka
    • Place of Presentation
      大阪 吉本ビル
    • Year and Date
      2014-07-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.2014

    • Author(s)
      Shibata M, Sato H, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T, Okano H, Suzuki N.
    • Organizer
      Pan-Asian/Pan-American Program, American Headache Society 2014, June 2014, Los Angeles.
    • Place of Presentation
      Hyatt Regency Century Plaza, Los Angeles, USA
    • Year and Date
      2014-06-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460706
  • [Presentation] 脳硬膜の神経原性炎症における三叉神経侵害刺激の関与について.2013

    • Author(s)
      海老根妙子、鳥海春樹、滝沢 翼、萱間洋平、黄 杏里、柴田 護、清水利彦、鈴木則宏
    • Organizer
      第41回日本頭痛学会
    • Place of Presentation
      岩手県盛岡市
    • Data Source
      KAKENHI-PROJECT-25460726
  • [Presentation] Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.2012

    • Author(s)
      Shibata M
    • Organizer
      European Headache and Migraine Trust International Congress 2012
    • Place of Presentation
      英国,ロンドン
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 三叉神経系の活性化によるCortical Spreading Depressionへの影響2011

    • Author(s)
      小泉健三、畝川美悠紀、鳥海春樹、柴田護、清水利彦、黒井俊哉、佐藤仁、舟久保恵美, 岩下達雄, 鈴木則宏
    • Organizer
      第39回日本頭痛学会総会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Botulinum neurotoxin type A decreases TRPV1 expression in trigeminal ganglion neurons by proteasomal degradation2011

    • Author(s)
      Mamoru Shibata
    • Organizer
      3rd Asian Regional Congress on Headache
    • Place of Presentation
      中国・北京
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 三叉神経系の活性化によるCortical Spreading Depressionへの影響.2011年11月埼玉.日本頭痛学会誌38:227,20112011

    • Author(s)
      鳥海春樹、海老根妙子、黒井俊哉、佐藤仁, 舟久保恵美、岩下達雄、小泉健三、柴田護、清水利彦、鈴木則宏
    • Organizer
      第39回日本頭痛学会総会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] A型ボツリヌス毒素は三叉神経節ニューロンのTRPV1細胞膜発現を低下させる-抗片頭痛薬効機序との関連2011

    • Author(s)
      柴田護、清水利彦、岩下達雄、鳥海春樹、舟久保恵美、小泉健三、佐藤仁、黒井俊哉、鈴木則宏
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Botulinum neurotoxin type A reduces TRPV1 expression in trigeminal ganglion neurons by inhibiting TRPV1 plasma membrane trafficking2011

    • Author(s)
      Shibata M, Shimizu T, Iwashita T, Toriumi H, Funakubo M, Koizumi K, Sato H, Kuroi T, Suzuki N
    • Organizer
      15^<th> Congress of the International Headache Society
    • Place of Presentation
      ベルリン,ドイツ
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] The effect of acute trigeminal activation on CSD threshold2011

    • Author(s)
      Toriumi H, Kuroi T, Sato H, Funakubo M, Iwashita T, Koizumi K, Shibata M, Shimizu T, Suzuki N
    • Organizer
      15^<th> Congress of the International Headache Society
    • Place of Presentation
      ベルリン,ドイツ
    • Year and Date
      2011-06-24
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 三叉神経領域におけるA型ボツリヌス毒素投与によるラット疼痛行動抑制効果について2011

    • Author(s)
      舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 海老根妙子, 佐藤仁, 黒井俊哉, 小泉健三, 鈴木則宏
    • Organizer
      第39回日本頭痛学会総会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Excess TRPV1 stimulation leads to the induction of autophagy2010

    • Author(s)
      Shibata M, Shimizu T, Funakubo M, Iwashita T, Toriumi H, Koizumi K, Itoh Y, Suzuki N
    • Organizer
      Neuroscience Meeting 2010
    • Place of Presentation
      San Diego
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 脳神経系の自律神経節におけるRAMP-1の分布-片頭痛の病態への関与の可能性ついて2010

    • Author(s)
      小泉健三, 清水利彦, 柴田護, 鳥海春樹, 岩下達雄, 舟久保恵美, 鈴木則宏
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] エタノールによるTRPV1を介したカスパーゼ-8活性化-片頭痛病態への関与(日本頭痛学会誌37:191,2010)2010

    • Author(s)
      舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 佐藤仁, 黒井俊哉, 小泉健三, 鈴木則宏
    • Organizer
      第38回日本頭痛学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] TRPV1による侵害受容で引き起こされる細胞死の誘導機構-片頭痛病態との関連性2010

    • Author(s)
      柴田護、舟久保恵美、清水利彦、岩下達雄、鳥海春樹、鈴木則宏
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 大規模疫学調査による大学病院職員における頭痛の実態2010

    • Author(s)
      鈴木則宏、石川良樹、五味慎太郎、伊東信彦、三宅仁、渡邉茂、横山雅子、清水利彦、柴田護
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 慢性片頭痛病態モデルを用いたラット三叉神経尾側核の免疫組織化学染色検討(日本頭痛学会誌37:192,2010)2010

    • Author(s)
      黒井俊哉, 鳥海春樹, 佐藤仁, 舟久保恵美, 岩下達雄, 小泉健三, 柴田護, 清水利彦, 鈴木則宏
    • Organizer
      第38回日本頭痛学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] RPV1高発現時のカプサイシン刺激による細胞死誘導機構-片頭痛病態への関与2010

    • Author(s)
      舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 小泉健三, 鈴木則宏
    • Organizer
      第32回日本疼痛学会
    • Place of Presentation
      京都
    • Year and Date
      2010-07-03
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] TRPV1-mediated autophagy : Relevance to remodeling of the sensory system2010

    • Author(s)
      Shibata M.
    • Organizer
      第38回日本頭痛学会サテライトシンポジウムMigraine Scientific Seminar 2010
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 閉経後の片頭痛患者の特徴に関する実態調査.(日本頭痛学会誌37:238,2010)2010

    • Author(s)
      牧田和也, 平沢晃, 柴田護, 清水利彦, 青木大輔, 鈴木則宏
    • Organizer
      第38回日本頭痛学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] A型ボツリヌス毒素の片頭痛予防効果に関する研究-TRPV1受容体の関与2010

    • Author(s)
      清水利彦, 柴田護, 鳥海春樹, 岩下達雄, 舟久保恵美, 小泉健三, 鈴木則宏
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 脳硬膜侵害刺激による三叉神経節神経細胞におけるERKリン酸化の経時変化2010

    • Author(s)
      岩下達雄, 清水利彦, 柴田護, 鳥海春樹, 舟久保恵美, 鈴木則宏
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] TRPV1高発現時のカプサイシン刺激によるカスパーゼ2の活性化.(日本頭痛学会誌37:194,2010)2010

    • Author(s)
      佐藤仁, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 小泉健三, 舟久保恵美, 黒井俊哉, 鈴木則宏
    • Organizer
      第38回日本頭痛学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] TRPV1受容体を介した三叉神経の侵害刺激がCSD発生に及ぼす影響.(日本頭痛学会誌37:193,2010)2010

    • Author(s)
      鳥海春樹, 畝川美悠紀, 黒井俊哉, 佐藤仁、舟久保恵美, 岩下達雄, 小泉健三, 柴田護, 清水利彦, 鈴木則宏
    • Organizer
      第38回日本頭痛学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 脳硬膜および顔面に分布する感覚神経線維の三叉神経節における局在について

    • Author(s)
      海老根妙子、鳥海春樹、滝沢 翼、萱間洋平、黄 杏里、柴田 護、清水利彦、鈴木則宏.
    • Organizer
      日本頭痛学会
    • Place of Presentation
      下関
    • Year and Date
      2014-11-14 – 2014-11-15
    • Data Source
      KAKENHI-PROJECT-25460726
  • [Presentation] Implication of TRPM8 in the TRPV1-mediated trigeminal nociception.

    • Author(s)
      Kayama Y, Shibata M, Takizawa T, Shimizu T, Toriumi H, Ebine T, Funakubo M, Iwashita T, Sato H, Suzuki N.
    • Organizer
      16th Congress of the International Headache Society 2013
    • Place of Presentation
      米国,ボストン
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 炎症性メディエーター存在下におけるTRPM8発現調節

    • Author(s)
      萱間洋平、柴田 護、滝沢 翼、清水利彦、鳥海春樹、海老根妙子、黄 杏里、鈴木則宏.
    • Organizer
      日本頭痛学会
    • Place of Presentation
      海峡メッセ下関(山口県下関市)
    • Year and Date
      2014-11-14 – 2014-11-15
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Differential cellular localization of antioxident enzymes in the trigeminal ganglion

    • Author(s)
      Shibata M
    • Organizer
      56th annual scientific meeting of american headache society
    • Place of Presentation
      Hyatt Regency Century Plaza (Los Angeles, CA, USA)
    • Year and Date
      2014-06-26 – 2014-06-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 皮質性拡延性抑制後の大脳皮質におけるHMGB1発現誘導

    • Author(s)
      滝沢 翼、柴田 護、萱間洋平、海老根妙子、佐藤 仁、黄杏里、鳥海春樹、清水利彦、鈴木則宏.
    • Organizer
      第55回日本神経学会総会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Capsaicin-induced nerve fiber degeneration in the spinal tract of the trigeminal nucleus.

    • Author(s)
      Shibata M, Ebine T, Nagai T, Toriumi H, Shimizu T, Iwashita T, Funakubo M, Takizawa T, Kayama Y, Suzuki N.
    • Organizer
      16th Congress of the International Headache Society 2013
    • Place of Presentation
      米国,ボストン
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Effect of cortical spreading depression on the phosphorylation of ERK in the trigeminal ganglion of rat.

    • Author(s)
      Iwashita T, Shimizu T, Shibata M, Toriumi H, Kayama Y, Ebine T, Takizawa T, Funakubo M, Suzuki N.
    • Organizer
      16th Congress of the International Headache Society 2013
    • Place of Presentation
      米国,ボストン
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] 皮質拡延性抑制後の大脳皮質におけるHMGB1発現誘導.

    • Author(s)
      滝沢 翼、柴田 護、萱間洋平、海老根妙子、清水利彦、鳥海春樹、黄 杏里、清水利彦、鈴木則宏.
    • Organizer
      日本頭痛学会
    • Place of Presentation
      海峡メッセ下関(山口県下関市)
    • Year and Date
      2014-11-14 – 2014-11-15
    • Data Source
      KAKENHI-PROJECT-22390182
  • [Presentation] Expression of high-mobility group box-1 in the cerebral cortex after cortical spreading depression.

    • Author(s)
      Takizawa T, Shibata M, Kayama Y, Shimizu T, Toriumi H, Ebine T, Koh A, Suzuki N.
    • Organizer
      European Headache and Migraine Trust International Congress 2014
    • Place of Presentation
      Bella Center (Cophenhegen, Denmark)
    • Year and Date
      2014-09-18 – 2014-09-21
    • Data Source
      KAKENHI-PROJECT-22390182
  • 1.  SHIMIZU Toshihiko (40265799)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 48 results
  • 2.  TORIUMI Haruki (30528203)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 3.  TAKEDA Hidetaka (70245489)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HAMADA Junichi (70180940)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  佐々木 貴浩 (60306694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SUZUKI Norihiro (10158975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 35 results
  • 7.  KOIZUMI Kenzo (30439070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 8.  FUNAKUBO Megumi (90548538)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 22 results
  • 9.  SUZUKI Shigeaki (50276242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  DEMBO Tomohisa (50306700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  ITOH Yoshiaki (90265786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  GOTOH Kyoko (90317107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  福内 靖男 (10051476)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  伊東 大介 (80286450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  EBINE Taeko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 16.  TOMITA Yutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  IZAWA Yoshikane
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  柚崎 通介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  畝川 美悠紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 20.  亀山 征史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  芝田 晋介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  岡野 栄之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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