Shibata Mamoru 柴田護

… Alternative Names

Researcher Number	60286466
Other IDs
Affiliation (Current)	2021: 東京歯科大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 慶應義塾大学, 医学部(信濃町), 講師 2017: 慶應義塾大学, 医学部, 講師 2010 – 2015: 慶應義塾大学, 医学部, 講師 2000 – 2001: 慶應義塾大学, 医学部, 助手 1997 – 1998: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurology / Pain science / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Pain science / Neurology / Neurology
Keywords	Principal Investigator 三叉神経節ニューロン / 片頭痛 / パーキンソン病 / 遺伝子治療 / レトロウィルス / neural stem cell / レトロウイルス / ミトコンドリア / オートファジー / ミトファジー … More Except Principal Investigator 片頭痛 / 皮質拡延性抑制 / 三叉神経節 / 三叉神経 / CGRP / TRPV1 / MTT / Alamar Blue / HMGB1 / アポトーシス / 大脳皮質性拡延性抑制 / 三叉神経血管系 / TRPV1受容体 / ERK / 硬膜 / 神経原性炎症 / 翼口蓋神経節 / アストロサイト / ニューロン / グルコース / グリコーゲン / ピルビン酸 / 乳酸 / 虚血 / TCA回路 / Naイオン / オリゴデンドロサイト / LDH / SBFI / ミトコンドリア / ASTROCYTE / NEURON / GLUCOSE / GLYCOGEN / PYRUVATE / LACTATE / a片頭痛 / 女性ホルモン / 光過敏 / エストロゲン / プロゲステロン / 性周期 / 神経科学 Less

Elucidation of the role of CGRP in migraine pathophysiology and application of oligonucleotide therapeutics to migraine treatmentPrincipal Investigator
- Principal Investigator
  
  柴田護
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Keio University
慢性疼痛が皮質拡延性に及ぼす影響－片頭痛の病態解析
- Principal Investigator
  
  清水利彦
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Keio University
Analysis of pain disease model-associated mitochondrial abnormalities in primary sensory neuronsPrincipal Investigator
- Principal Investigator
  
  Shibata Mamoru
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Keio University
Trigeminal contribution to the neurogenic inflammation in the dura mater
- Principal Investigator
  
  Shimizu Toshihiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Keio University
Research on migraine pathophysiology related to cortical spreading depression
- Principal Investigator
  
  SUZUKI Norihiro
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Keio University
Clinical and basic investigation on the pathogenesis of multiple system atrophyPrincipal Investigator
- Principal Investigator
  
  HAMADA Junichi, 柴田護
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Keio University
Roles of astroglial energy metabolism in ischemic neuronal cell damage: an implication for the treatment of cerebral ischemia
- Principal Investigator
  
  TAKEDA Hidetaka, 福内靖男
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Keio University
遺伝子導入neural stem cellを用いたパーキンソン病モデルの移植治療Principal Investigator
- Principal Investigator
  
  柴田護
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Keio University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] 薬物乱用頭痛,慢性連日性頭痛.アクチュアル脳・神経疾患の臨床.識る診る治す頭痛のすべて(鈴木則宏編集)2011
- Author(s)
  柴田護
- Publisher
  中山書店,東京
- Data Source
  KAKENHI-PROJECT-22390182
[Book] パーキンソン病の頭痛,パーキンソン病臨床の諸問題2(山本光利編)2011
- Author(s)
  柴田護
- Publisher
  中外医学社, 東京
- Data Source
  KAKENHI-PROJECT-22390182
[Book] 慢性頭痛/片頭痛ポケット判診療ガイドラインUP-TO-DATE.(門脇孝、小室一成、宮地良樹監修)2010
- Author(s)
  柴田護、鈴木則宏
- Publisher
  メディカルレビュー社、大阪・東京
- Data Source
  KAKENHI-PROJECT-22390182
[Book] これでわかる頭痛診療-頭痛外来でのノウハウとコツ2010
- Author(s)
  鈴木則宏、清水利彦、柴田護
- Publisher
  南江堂、東京
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology.2018
- Author(s)
  Kayama Y, Shibata M, Takizawa T, Ibata K, Shimizu T, Ebine T, Toriumi H, Yuzaki M, Suzuki N.
- Journal Title
  
  Cephalalgia
  
  Volume: 38(5) Pages: 833-845
- DOI
  10.1177/0333102417712719
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06461, KAKENHI-PROJECT-26460706, KAKENHI-PROJECT-15H05772
[Journal Article] Signaling Pathways Relevant to Nerve Growth Factor-induced Upregulation of Transient Receptor Potential M8 Expression.2017
- Author(s)
  Kayama Y, Shibata M, Takizawa T, Ibata K, Nakahara J, Shimizu T, Toriumi H, Yuzaki M, Suzuki N.
- Journal Title
  
  Neuroscience
  
  Volume: 367 Pages: 178-188
- DOI
  10.1016/j.neuroscience.2017.10.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] High-mobility group box 1 (HMGB1) is an important mediator of microglial activation induced by cortical spreading depression.2017
- Author(s)
  Takizawa T., Shibata M., Kayama Y., Shimizu T., Toriumi H., Ebine T., Unekawa M., Koh A., Yoshimura A., Suzuki N.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 37 Pages: 890-901
- DOI
  10.1177/0271678x16647398
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350981, KAKENHI-PROJECT-26460706
[Journal Article] Exploring the role of microglia in cortical spreading depression in neurological disease.2017
- Author(s)
  Shibata M, Suzuki N.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 37 Pages: 1182-1191
- DOI
  10.1177/0271678x17690537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] Possible Involvement of Hypotension in Postprandial Headache: A Case Series.2017
- Author(s)
  Takizawa T, Shibata M, Hiraide T, Seki M, Takahashi S, Suzuki N.
- Journal Title
  
  Headache
  
  Volume: 57 Pages: 1443-1448
- DOI
  10.1111/head.13136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] How have animal studies contributed to the development of migraine research?2016
- Author(s)
  柴田　護
- Journal Title
  
  日本頭痛学会誌
  
  Volume: 43 Pages: 61-64
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] Repetitive trigeminal nociceptive stimulation in rats increases their susceptibility to cortical spreading depression.2016
- Author(s)
  Toriumi H, Shimizu T, Ebine T, Takizawa T, Kayama Y, Koh A, Shibata M, Suzuki N
- Journal Title
  
  Neurosci Res
  
  Volume: 106 Pages: 74-78
- DOI
  10.1016/j.neures.2015.12.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460726
[Journal Article] Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice.2016
- Author(s)
  Takizawa T, Shibata M, Kayama Y, Toriumi H, Ebine T, Koh A, Shimizu T, Suzuki N
- Journal Title
  
  Ｃｅｐｈａｌａｌｇｉａ
  
  Volume: 印刷中 Pages: 44-52
- DOI
  10.1177/0333102415580100
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-25460726, KAKENHI-PROJECT-26460706
[Journal Article] Alterations in the threshold of the potassium concentration to evoke cortical spreading depression during the natural estrous cycle in mice.2016
- Author(s)
  Taeko Ebine, Haruki Toriumi, Toshihiko Shimizu, Miyuki Unekawa, Tsubasa Takizawa, Yohei Kayama, Mamoru Shibata, Norihiro Suzuki
- Journal Title
  
  Neurosci. Res.
  
  Volume: 112 Pages: 57-62
- DOI
  10.1016/j.neures.2016.06.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08996, KAKENHI-PROJECT-26350981
[Journal Article] Adult-onset recurrent painful ophthalmoplegic neuropathy displaying atypical oculomotor nerve gadolinium-enhancement pattern in the orbit and cavernous sinus.2016
- Author(s)
  Takizawa T, Shibata M*, Fujiwara H, Shimizu T, Momoshima S, Suzuki N.
- Journal Title
  
  Cephalalgia
  
  Volume: 36 Pages: 199-200
- DOI
  10.1177/0333102415583987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] ミクログリアと皮質拡延性抑制.2016
- Author(s)
  柴田　護.
- Journal Title
  
  Annual Review神経2016
  
  Volume: - Pages: 63-68
- Open Access
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] Clinical utility of triptans in the management of headache attributed to dural arteriovenous fistula involving the cavernous sinus.2015
- Author(s)
  39.Osaka M, Shibata M#, Oki K, Yamada S, Kufukibara K, Akiyama T, Yoshida K, Suzuki N. (#corresponding author)
- Journal Title
  
  J Neurol Sci
  
  Volume: 349 Pages: 260-261
- DOI
  10.1016/j.jns.2015.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] Temporal profiles of high-mobility group box 1 expression levels after cortical spreading depression in mice.2015
- Author(s)
  Takizawa T, Shibata M, Kayama Y, Toriumi H, Ebine T, Koh A, Shimizu T, Suzuki.
- Journal Title
  
  Cephalalgia
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] Intracranial hemorrhage due to venous thrombosis of developmental venous anomaly during pregnancy.2015
- Author(s)
  Seki M, Shibata M, Itoh Y, Suzuki N.
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] 薬剤の使用過多による頭痛 (薬物乱用頭痛, MOH)の病態生理と診断.2014
- Author(s)
  柴田　護
- Journal Title
  
  神経内科
  
  Volume: 81 Pages: 417-422
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] 片頭痛のメカニズム2014
- Author(s)
  柴田　護
- Journal Title
  
  日本頭痛学会誌
  
  Volume: ４１ Pages: 26-29
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] 専門医部会　シリーズ: 患者の言葉・身体所見を読み解く　頭痛～病歴と画像診断から診断を考える～.2014
- Author(s)
  柴田　護
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 103 Pages: 2841-2844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460706
[Journal Article] 片頭痛の予後はどうか？2013
- Author(s)
  柴田　護
- Journal Title
  
  日本頭痛学会誌
  
  Volume: 40 Pages: 30-31
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] Activation of extracellular signal-regulated kinase in the trigeminal ganglion following both treatment of the dura mater with capsaicin and cortical spreading depression.2013
- Author(s)
  Iwashita T, Shimizu T, Shibata M, Toriumi H, Ebine T, Funakubo M, Suzuki N.
- Journal Title
  
  Neurosci Res.
  
  Volume: 77 Pages: 110-119
- DOI
  10.1016/j.neures.2013.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-24590732
[Journal Article] 片頭痛慢性化の病態生理2013
- Author(s)
  柴田　護
- Journal Title
  
  臨床神経学
  
  Volume: 53 Pages: 1220-1222
- NAID
  130004505393
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.2013
- Author(s)
  Sato H, Shibata M, Shimizu T, Shibata S, Haruki T, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T. Okano H. Suzuki N
- Journal Title
  
  Neuroscience.
  
  Volume: 248 Pages: 345-348
- DOI
  10.1016/j.neuroscience.2013.06.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00978, KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24590732
[Journal Article] 片頭痛慢性化のメカニズム2012
- Author(s)
  柴田　護
- Journal Title
  
  臨床神経学
  
  Volume: 52 Pages: 1012-1013
- NAID
  130004505041
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] Migraine Future Research Perspectives日本の最新の研究からTRPV1介在性の自食作用感覚システム再構築との関連2011
- Author(s)
  柴田護
- Journal Title
  
  Headache Clinical & Science
  
  Volume: 2(解説) Pages: 57-58
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] 片頭痛の病態研究および治療に関する最近の知見2011
- Author(s)
  清水利彦、柴田護、鈴木則宏
- Journal Title
  
  臨床神経
  
  Volume: 51 Pages: 103-109
- NAID
  10031163984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] TRPV1発現量に応じたカプサイシン刺激時の細胞死誘導機構片頭痛慢性化への関与2011
- Author(s)
  舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 鈴木則宏
- Journal Title
  
  日本頭痛学会誌
  
  Volume: 38 Pages: 21-24
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] Developmental and circulatory profile of the diploic veins2011
- Author(s)
  Toriumi H, Shimizu T, Shibata M, Unekawa M, Tomita Y, Tomita M, Suzuki N
- Journal Title
  
  Microvascular Research
  
  Volume: 81 Pages: 97-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390182
[Journal Article] テーラーメード治療のための治療薬の選択と使用法ガイドライン頭痛(片頭痛,緊張型頭痛)2010
- Author(s)
  柴田護
- Journal Title
  
  Medical Practice
  
  Volume: Vol.27 臨時増刊号 Pages: 194-200
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Development of photophobia-like behaviors after cortical spreading depression in mice2018
- Author(s)
  Kitagawa S,Shibata M, Unekawa M, Kayama Y, Hua TC , Shimizu T,Suzuki N, Nakahara J
- Organizer
  第46回日本頭痛学会総会
- Data Source
  KAKENHI-PROJECT-16K08996
[Presentation] Facial TRPM8 stimulation ameliorates thermal hyperalgesia in a mouse migraine model.2017
- Author(s)
  Kayama S, Shibata M, Takizawa T, Shimizu T, Toriumi H, Ebine T, Suzuki N.
- Organizer
  IHC2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Cortical spreading depression alters the progranulin expression in cortical neurons.2017
- Author(s)
  Kitagawa S, Takizawa T, Kayama Y, Toriumi H, Shimizu T, Shibata M, Suzuki N.
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] 片頭痛治療のすべて病態から見た新しい治療の展望. 片頭痛の新しい治療薬.2017
- Author(s)
  柴田　護
- Organizer
  第35回日本神経治療学会総会.
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Animal models of migraine: Trigeminovascular system.2017
- Author(s)
  Shibata M
- Organizer
  第45回日本頭痛学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] 頭痛の病態に関わるHotな分子たち. PACAPとCGRP.2017
- Author(s)
  Shibata M
- Organizer
  第45回日本頭痛学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Symposium 3: New therapeutic horizons for migraine. Introduction to novel migraine therapies on the horizon.2016
- Author(s)
  Shibata M.
- Organizer
  第44回日本頭痛学会総会
- Place of Presentation
  Ｗｅｓｔｉｎ都ホテル京都 (京都府京都市)
- Year and Date
  2016-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Temporal profiles of TRPM8 and TRPV1 expression in the trigeminal ganglion neurons after CFA-induced inflammation.2016
- Author(s)
  Kayama Y, Shibata M, Takizawa T, Shimizu T, Toriumi H, Ebine T, Suzuki N.
- Organizer
  EHMTIC2016
- Place of Presentation
  Glasgow (Scotland)
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] HMGB1 is an important mediator of multiple CSD-induced microalial activation in the cerebral cortex.2016
- Author(s)
  Shibata M.
- Organizer
  The 6th Asian Regional Conference for Headache
- Place of Presentation
  Seoul (South Korea)
- Year and Date
  2016-10-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] なおる神経内科「片頭痛の現在・過去・未来」CGRP拮抗薬.2016
- Author(s)
  柴田　護.
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場 (兵庫県神戸市)
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Distribution of the calcitonin gene-related peptide receptors in the sphenopalatine ganglion of rat.2015
- Author(s)
  Koh A, Shimizu T, Shibata M, Takizawa T, Kayama Y, Ebine T, Toriumi H, Suzuki N
- Organizer
  17th Congress of the International Headache Society 2015 (IHC2015)
- Place of Presentation
  Valencia, Spain
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460726
[Presentation] 慢性片頭痛と反復性片頭痛はどう違うか?2015
- Author(s)
  柴田　護.
- Organizer
  第43回日本頭痛学会総会
- Place of Presentation
  京王プラザホテル (東京新宿区)
- Year and Date
  2015-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Mechanism of cortical microglial activation after cortical spreading depression.2015
- Author(s)
  Shibata M.
- Organizer
  Pan-Asian/Pan-American Program, AHS57th Annual Scientific Meeting.
- Place of Presentation
  Ｇｒａｎｄ　Ｈｙａｔｔ　Washington, Ｗａｓｈｉｎｇｔｏｎ　DC. (USA)
- Year and Date
  2015-06-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Microglial activation by multiple inductions of cortical spreading depression.2015
- Author(s)
  Takizawa T, Shibata M, Kayama Y, Shimizu T, Toriumi H, Ebine T, Koh A, Suzuki N.
- Organizer
  Congress of the International Headache Society 2015 (IHC2015)
- Place of Presentation
  Valencia, Spain
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460726
[Presentation] Microglial activation by multiple inductions of cortical spreading depression.2015
- Author(s)
  Takizawa T, Shibata M, Kayama Y, Shimizu T, Toriumi H, Ebine T, Koh A, Suzuki N.
- Organizer
  17th Congress of the International Headache Society 2015
- Place of Presentation
  Valencia, Spain
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460726
[Presentation] How have animal studoes contributed to the elucidation of migraine pathophysiology?2015
- Author(s)
  Shibata M.
- Organizer
  第43回日本頭痛学会総会
- Place of Presentation
  京王プラザホテル (東京新宿区)
- Year and Date
  2015-11-13
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] 頭痛のanatomy2014
- Author(s)
  柴田　護
- Organizer
  Headache Master School Japan Osaka
- Place of Presentation
  大阪　吉本ビル
- Year and Date
  2014-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] 片頭痛の病態生理2014
- Author(s)
  柴田　護
- Organizer
  Headache Master School Japan Tokyo
- Place of Presentation
  東京都市センター
- Year and Date
  2014-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] 片頭痛の新たな主役たち　片頭痛慢性化2014
- Author(s)
  柴田　護
- Organizer
  第42回日本頭痛学会総会
- Place of Presentation
  山口県下関市海峡メッセ
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] TACsの治療2014
- Author(s)
  柴田　護
- Organizer
  Headache Master School Japan Osaka
- Place of Presentation
  大阪吉本ビル
- Year and Date
  2014-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.2014
- Author(s)
  Shibata M, Sato H, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T, Okano H, Suzuki N.
- Organizer
  Pan-Asian/Pan-American Program, American Headache Society 2014, June 2014, Los Angeles.
- Place of Presentation
  Hyatt Regency Century Plaza, Los Angeles, USA
- Year and Date
  2014-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26460706
[Presentation] 脳硬膜の神経原性炎症における三叉神経侵害刺激の関与について．2013
- Author(s)
  海老根妙子、鳥海春樹、滝沢翼、萱間洋平、黄杏里、柴田　護、清水利彦、鈴木則宏
- Organizer
  第41回日本頭痛学会
- Place of Presentation
  岩手県盛岡市
- Data Source
  KAKENHI-PROJECT-25460726
[Presentation] Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.2012
- Author(s)
  Shibata M
- Organizer
  European Headache and Migraine Trust International Congress 2012
- Place of Presentation
  英国，ロンドン
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 三叉神経系の活性化によるCortical Spreading Depressionへの影響2011
- Author(s)
  小泉健三、畝川美悠紀、鳥海春樹、柴田護、清水利彦、黒井俊哉、佐藤仁、舟久保恵美, 岩下達雄, 鈴木則宏
- Organizer
  第39回日本頭痛学会総会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Botulinum neurotoxin type A decreases TRPV1 expression in trigeminal ganglion neurons by proteasomal degradation2011
- Author(s)
  Mamoru Shibata
- Organizer
  3rd Asian Regional Congress on Headache
- Place of Presentation
  中国・北京
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 三叉神経系の活性化によるCortical Spreading Depressionへの影響.2011年11月埼玉.日本頭痛学会誌38:227,20112011
- Author(s)
  鳥海春樹、海老根妙子、黒井俊哉、佐藤仁, 舟久保恵美、岩下達雄、小泉健三、柴田護、清水利彦、鈴木則宏
- Organizer
  第39回日本頭痛学会総会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] A型ボツリヌス毒素は三叉神経節ニューロンのTRPV1細胞膜発現を低下させる-抗片頭痛薬効機序との関連2011
- Author(s)
  柴田護、清水利彦、岩下達雄、鳥海春樹、舟久保恵美、小泉健三、佐藤仁、黒井俊哉、鈴木則宏
- Organizer
  第52回日本神経学会総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Botulinum neurotoxin type A reduces TRPV1 expression in trigeminal ganglion neurons by inhibiting TRPV1 plasma membrane trafficking2011
- Author(s)
  Shibata M, Shimizu T, Iwashita T, Toriumi H, Funakubo M, Koizumi K, Sato H, Kuroi T, Suzuki N
- Organizer
  15^<th> Congress of the International Headache Society
- Place of Presentation
  ベルリン,ドイツ
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] The effect of acute trigeminal activation on CSD threshold2011
- Author(s)
  Toriumi H, Kuroi T, Sato H, Funakubo M, Iwashita T, Koizumi K, Shibata M, Shimizu T, Suzuki N
- Organizer
  15^<th> Congress of the International Headache Society
- Place of Presentation
  ベルリン,ドイツ
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 三叉神経領域におけるA型ボツリヌス毒素投与によるラット疼痛行動抑制効果について2011
- Author(s)
  舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 海老根妙子, 佐藤仁, 黒井俊哉, 小泉健三, 鈴木則宏
- Organizer
  第39回日本頭痛学会総会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Excess TRPV1 stimulation leads to the induction of autophagy2010
- Author(s)
  Shibata M, Shimizu T, Funakubo M, Iwashita T, Toriumi H, Koizumi K, Itoh Y, Suzuki N
- Organizer
  Neuroscience Meeting 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 脳神経系の自律神経節におけるRAMP-1の分布-片頭痛の病態への関与の可能性ついて2010
- Author(s)
  小泉健三, 清水利彦, 柴田護, 鳥海春樹, 岩下達雄, 舟久保恵美, 鈴木則宏
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] エタノールによるTRPV1を介したカスパーゼ-8活性化-片頭痛病態への関与(日本頭痛学会誌37:191,2010)2010
- Author(s)
  舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 佐藤仁, 黒井俊哉, 小泉健三, 鈴木則宏
- Organizer
  第38回日本頭痛学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] TRPV1による侵害受容で引き起こされる細胞死の誘導機構-片頭痛病態との関連性2010
- Author(s)
  柴田護、舟久保恵美、清水利彦、岩下達雄、鳥海春樹、鈴木則宏
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 大規模疫学調査による大学病院職員における頭痛の実態2010
- Author(s)
  鈴木則宏、石川良樹、五味慎太郎、伊東信彦、三宅仁、渡邉茂、横山雅子、清水利彦、柴田護
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 慢性片頭痛病態モデルを用いたラット三叉神経尾側核の免疫組織化学染色検討(日本頭痛学会誌37:192,2010)2010
- Author(s)
  黒井俊哉, 鳥海春樹, 佐藤仁, 舟久保恵美, 岩下達雄, 小泉健三, 柴田護, 清水利彦, 鈴木則宏
- Organizer
  第38回日本頭痛学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] RPV1高発現時のカプサイシン刺激による細胞死誘導機構-片頭痛病態への関与2010
- Author(s)
  舟久保恵美, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 小泉健三, 鈴木則宏
- Organizer
  第32回日本疼痛学会
- Place of Presentation
  京都
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] TRPV1-mediated autophagy : Relevance to remodeling of the sensory system2010
- Author(s)
  Shibata M.
- Organizer
  第38回日本頭痛学会サテライトシンポジウムMigraine Scientific Seminar 2010
- Place of Presentation
  Tokyo
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 閉経後の片頭痛患者の特徴に関する実態調査.(日本頭痛学会誌37:238,2010)2010
- Author(s)
  牧田和也, 平沢晃, 柴田護, 清水利彦, 青木大輔, 鈴木則宏
- Organizer
  第38回日本頭痛学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] A型ボツリヌス毒素の片頭痛予防効果に関する研究-TRPV1受容体の関与2010
- Author(s)
  清水利彦, 柴田護, 鳥海春樹, 岩下達雄, 舟久保恵美, 小泉健三, 鈴木則宏
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 脳硬膜侵害刺激による三叉神経節神経細胞におけるERKリン酸化の経時変化2010
- Author(s)
  岩下達雄, 清水利彦, 柴田護, 鳥海春樹, 舟久保恵美, 鈴木則宏
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] TRPV1高発現時のカプサイシン刺激によるカスパーゼ2の活性化.(日本頭痛学会誌37:194,2010)2010
- Author(s)
  佐藤仁, 柴田護, 清水利彦, 岩下達雄, 鳥海春樹, 小泉健三, 舟久保恵美, 黒井俊哉, 鈴木則宏
- Organizer
  第38回日本頭痛学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] TRPV1受容体を介した三叉神経の侵害刺激がCSD発生に及ぼす影響.(日本頭痛学会誌37:193,2010)2010
- Author(s)
  鳥海春樹, 畝川美悠紀, 黒井俊哉, 佐藤仁、舟久保恵美, 岩下達雄, 小泉健三, 柴田護, 清水利彦, 鈴木則宏
- Organizer
  第38回日本頭痛学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 脳硬膜および顔面に分布する感覚神経線維の三叉神経節における局在について
- Author(s)
  海老根妙子、鳥海春樹、滝沢翼、萱間洋平、黄杏里、柴田　護、清水利彦、鈴木則宏．
- Organizer
  日本頭痛学会
- Place of Presentation
  下関
- Year and Date
  2014-11-14 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-25460726
[Presentation] Implication of TRPM8 in the TRPV1-mediated trigeminal nociception.
- Author(s)
  Kayama Y, Shibata M, Takizawa T, Shimizu T, Toriumi H, Ebine T, Funakubo M, Iwashita T, Sato H, Suzuki N.
- Organizer
  16th Congress of the International Headache Society 2013
- Place of Presentation
  米国，ボストン
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 炎症性メディエーター存在下におけるTRPM８発現調節
- Author(s)
  萱間洋平、柴田　護、滝沢翼、清水利彦、鳥海春樹、海老根妙子、黄　杏里、鈴木則宏．
- Organizer
  日本頭痛学会
- Place of Presentation
  海峡メッセ下関（山口県下関市)
- Year and Date
  2014-11-14 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Differential cellular localization of antioxident enzymes in the trigeminal ganglion
- Author(s)
  Shibata M
- Organizer
  56th annual scientific meeting of american headache society
- Place of Presentation
  Hyatt Regency Century Plaza (Los Angeles, CA, USA)
- Year and Date
  2014-06-26 – 2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 皮質性拡延性抑制後の大脳皮質におけるHMGB1発現誘導
- Author(s)
  滝沢　翼、柴田　護、萱間洋平、海老根妙子、佐藤　仁、黄杏里、鳥海春樹、清水利彦、鈴木則宏.
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Capsaicin-induced nerve fiber degeneration in the spinal tract of the trigeminal nucleus.
- Author(s)
  Shibata M, Ebine T, Nagai T, Toriumi H, Shimizu T, Iwashita T, Funakubo M, Takizawa T, Kayama Y, Suzuki N.
- Organizer
  16th Congress of the International Headache Society 2013
- Place of Presentation
  米国，ボストン
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Effect of cortical spreading depression on the phosphorylation of ERK in the trigeminal ganglion of rat.
- Author(s)
  Iwashita T, Shimizu T, Shibata M, Toriumi H, Kayama Y, Ebine T, Takizawa T, Funakubo M, Suzuki N.
- Organizer
  16th Congress of the International Headache Society 2013
- Place of Presentation
  米国，ボストン
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] 皮質拡延性抑制後の大脳皮質におけるHMGB1発現誘導．
- Author(s)
  滝沢　翼、柴田　護、萱間洋平、海老根妙子、清水利彦、鳥海春樹、黄　杏里、清水利彦、鈴木則宏．
- Organizer
  日本頭痛学会
- Place of Presentation
  海峡メッセ下関（山口県下関市)
- Year and Date
  2014-11-14 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-22390182
[Presentation] Expression of high-mobility group box-1 in the cerebral cortex after cortical spreading depression.
- Author(s)
  Takizawa T, Shibata M, Kayama Y, Shimizu T, Toriumi H, Ebine T, Koh A, Suzuki N.
- Organizer
  European Headache and Migraine Trust International Congress 2014
- Place of Presentation
  Bella Center (Cophenhegen, Denmark)
- Year and Date
  2014-09-18 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-22390182

1. SHIMIZU Toshihiko (40265799)

# of Collaborated Projects: 4 results

# of Collaborated Products: 49 results
2. TORIUMI Haruki (30528203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
3. TAKEDA Hidetaka (70245489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HAMADA Junichi (70180940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 佐々木貴浩 (60306694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SUZUKI Norihiro (10158975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 35 results
7. KOIZUMI Kenzo (30439070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
8. FUNAKUBO Megumi (90548538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
9. SUZUKI Shigeaki (50276242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. DEMBO Tomohisa (50306700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITOH Yoshiaki (90265786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GOTOH Kyoko (90317107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 福内靖男 (10051476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 伊東大介 (80286450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. EBINE Taeko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 柚崎通介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 畝川美悠紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 芝田晋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡野栄之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibata Mamoru 柴田 護

SHIBATA Mamoru 柴田 護

柴田 護 シバタ マモル

Research Projects

Research Products

Co-Researchers

Elucidation of the role of CGRP in migraine pathophysiology and application of oligonucleotide therapeutics to migraine treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

慢性疼痛が皮質拡延性に及ぼす影響－片頭痛の病態解析

Principal Investigator

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Analysis of pain disease model-associated mitochondrial abnormalities in primary sensory neuronsPrincipal Investigator

Principal Investigator

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Trigeminal contribution to the neurogenic inflammation in the dura mater

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Research on migraine pathophysiology related to cortical spreading depression

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Clinical and basic investigation on the pathogenesis of multiple system atrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Roles of astroglial energy metabolism in ischemic neuronal cell damage: an implication for the treatment of cerebral ischemia

Principal Investigator

Project Period (FY)

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Research Institution

遺伝子導入neural stem cellを用いたパーキンソン病モデルの移植治療Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] 薬物乱用頭痛,慢性連日性頭痛.アクチュアル脳・神経疾患の臨床.識る診る治す頭痛のすべて(鈴木則宏編集)2011

Author(s)

Publisher

Data Source

[Book] パーキンソン病の頭痛,パーキンソン病臨床の諸問題2(山本光利編)2011

Author(s)

Publisher

Data Source

[Book] 慢性頭痛/片頭痛 ポケット判 診療ガイドラインUP-TO-DATE.(門脇孝、小室一成、宮地良樹監修)2010

Author(s)

Publisher

Data Source

[Book] これでわかる頭痛診療-頭痛外来でのノウハウとコツ2010

Author(s)

Publisher

Data Source

[Journal Article] Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signaling Pathways Relevant to Nerve Growth Factor-induced Upregulation of Transient Receptor Potential M8 Expression.2017

Author(s)

Journal Title

DOI

Data Source

Shibata Mamoru 柴田護

SHIBATA Mamoru 柴田護

柴田護シバタマモル

[Book] 慢性頭痛/片頭痛ポケット判診療ガイドラインUP-TO-DATE.(門脇孝、小室一成、宮地良樹監修)2010

[Journal Article] 専門医部会　シリーズ: 患者の言葉・身体所見を読み解く　頭痛～病歴と画像診断から診断を考える～.2014