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HATANO Taku  波田野 琢

Researcher Number 60338390
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6808-0444
Affiliation (Current) 2025: 順天堂大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 順天堂大学, 大学院医学研究科, 准教授
2022: 順天堂大学, 大学院医学研究科, 先任准教授
2018 – 2020: 順天堂大学, 医学(系)研究科(研究院), 准教授
2011 – 2017: 順天堂大学, 医学部, 准教授
2008 – 2010: Juntendo University, 医学部, 助教
2009: 医学部, 助教
2009: 順天堂大学, 医学部・神経学, 助教
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related / Neuroscience in general
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Medium-sized Section 52:General internal medicine and related fields / Neurology / Basic Section 52010:General internal medicine-related / Basic Section 51030:Pathophysiologic neuroscience-related / Food science / Biological Sciences
Keywords
Principal Investigator
パーキンソン病 / 膜輸送 / レヴィ小体 / α-シヌクレイン / 家族性パーキンソン病 / アミロイドβ / タウタンパク質 / αーシヌクレイノパチー / αーシヌクレイン / バイオマーカー … More / 血漿交換療法 / αシヌクレイン / シヌクレイノパチー / IP/RT-QuIC / 多系統萎縮症 / Lewy小体 / シナプス終末 / 放出機能 / 脂質代謝異常 / C19orf72 / リン脂質 / リン脂質代謝 / リノール酸 / PLA2G6 / PARK14 / Lipid raft / Saposin / 脂質代謝酵素 / Lipid enzymes / Glucocerebrosidase / Parkinson's disease / Immunoisolation / FRET / Synaptophysin / Rab3A / synaptophysin / シナプトソーム / DJ-1 / exocytosis / PARK8 / iRNA / LRRK2 / Exocytosis / LRRK2 PARK8 … More
Except Principal Investigator
パーキンソン病 / オートファジー / 虫垂 / αシニクレイン / α-シヌクレイン / ミトコンドリア / 多系統萎縮症 (MSA) / α-synuclein (αS) / パーキンソン病 (PD) / 多系統萎縮(MSA) / α-Synuclein(αS) / パーキンソン病(PD) / バイオマーカー / 多系統萎縮(MSA) / レヴィ小体 / α-Synuclein(αS) / パーキンソン病(PD) / 骨量 / 骨格筋量 / 多系統萎縮症 / 進行性核上性麻痺 / 骨粗鬆症 / サルコペニア / パーキンソニズム / 脂肪酸合成蛋白 / αシヌクレイン / 虫垂炎 / ASシード / 慢性虫垂炎 / 虫垂切除 / 脂肪代謝 / 免疫電子顕微鏡 / リン酸化シヌクレイン / シヌクレイン / 黒質 / 線条体 / 伝播 / p62 / 伝播モデル / 凝集体 / 腸脳連関 / 腸脳関連 / α-シヌクレイン(AS) / 制御性T細胞 / Programmed cell death-1 / PLA2G6 / 封入体 / 脂質代謝 / GBA / CHCHD2 / ATP13A2 / リソソーム / 神経科学 / カフェイン代謝 / 代謝 / カフェイン / ミトファジー / 共通機構 / DJ-1 / 学習能力 / 遺伝性パーキンソン病 / 蛋白分解系 / 品質管理 / Mitophagy / CCCP / PINK1 / Parkin Less
  • Research Projects

    (16 results)
  • Research Products

    (218 results)
  • Co-Researchers

    (65 People)
  •  ASシード構造の差異に基づくシヌクレイノパチーの臨床病理学的多様性の解明Principal Investigator

    • Principal Investigator
      波田野 琢
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University
  •  虫垂切除がパーキンソン病に与える影響に関する機構解明

    • Principal Investigator
      福永 哲
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Juntendo University
  •  Japanese prospective multicenter study on the prognostic influence of sarcopenia and osteoporosis in Parkinsonism

    • Principal Investigator
      饗場 郁子
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Higashinagoya National Hospital
  •  Elucidation of the Pathology of Synucleinopathies and Development of New Therapies Focused on Serum Alpha-Synuclein SeedsPrincipal Investigator

    • Principal Investigator
      Taku Hatano
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Juntendo University
  •  Mechanism elucidation for influences of the Parkinson disease after appendectomy

    • Principal Investigator
      Fukunaga Tetsu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Juntendo University
  •  Elucidation of transmission and aggregation mechanisms of alpha-synuclein as a major component of Lewy body and development of disease-modifying therapies for synucleinopathies

    • Principal Investigator
      Hattori Nobutaka
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University
  •  Correlative light and electron microscopy (CLEM) to identify propagating synuclein aggregates in the brain

    • Principal Investigator
      Koike Masato
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Juntendo University
  •  Pathogenesis role of programmed cell death-1 in Parkinson's disease mouse model

    • Principal Investigator
      Hattori Nobutaka
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University
  •  Examination of Caffeine Metabolism Changes and Parkinson's Disease Symptom Correlation Based on Metabolite-Related Gene Analysis

    • Principal Investigator
      SUMIYOSHI KATSUHIKO
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Tokiwa University
  •  Pathomechanisms of Parkinson disease due to dysfunction of iPLA2G6Principal Investigator

    • Principal Investigator
      Hatano Taku
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  Analysis of lipid composition in hereditary Parkinson's Disease and the association with the pathology

    • Principal Investigator
      Hattori Nobutaka
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  Glucocerebrosidase associates with membrane trafficking systemPrincipal Investigator

    • Principal Investigator
      Hatano Taku
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  DJ-1 associates with membrane trafficking system.Principal Investigator

    • Principal Investigator
      HATANO Taku
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      Juntendo University
  •  Effects of mitophagy on cell death in Parkinson's disease model cells

    • Principal Investigator
      SAIKI Shinji
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  To elucidate the pathogenesis of Parkinson' s disease and to develop a new therapy for the disease

    • Principal Investigator
      HATTORI Nobutaka
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
  •  LRRK2 associates with the membrane trafficking system.Principal Investigator

    • Principal Investigator
      HATANO Taku
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Patent Other

  • [Book] 順天堂大学脳神経内科ではこうしている 最新パーキンソン病診療2021

    • Author(s)
      波田野琢 (服部信孝編)
    • Total Pages
      224
    • Publisher
      日本醫事新報社
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Book] 神経内科clinical questions & pearls パーキンソン病2019

    • Author(s)
      服部信孝、下泰司、波田野琢
    • Total Pages
      335
    • Publisher
      中外医学社
    • ISBN
      9784498328044
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Book] 神経内科外来シリーズ2 パーキンソン病外来 荒木信夫,山元敏正,高橋一司 編2016

    • Author(s)
      波田野 琢,服部 信孝
    • Total Pages
      264
    • Publisher
      メジカルビュー社
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Book] 神経内科外来シリーズ2 パーキンソン病外来2016

    • Author(s)
      波田野琢 服部信孝
    • Total Pages
      264
    • Publisher
      メジカルビュー社
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Book] 神経内科ハンドブック 鑑別診断と治療 第5版 水野美邦 編2016

    • Author(s)
      波田野 琢,水野 美邦
    • Total Pages
      1337
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Book] Movement Disorders in Neurologic and Systemic Diesase2014

    • Author(s)
      Hatano T, Kubo S. I., Hattori N, Mizuno Y
    • Total Pages
      470
    • Publisher
      Cambridge
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Book] Etiology and Pathophysiology of Parkinson’s disease.2011

    • Author(s)
      Hatano T, Hattori N
    • Publisher
      InTech
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Book] Parkinson Disease2011

    • Author(s)
      Hatano T and Hattori N
    • Publisher
      In eLS. Chichester: Johon Wiley & Sons
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Book] Etiology and pathogenesis of Parkinson's disease. In: Rana AQ, ed.Etiology and pathophysiology of Parkinson's disease.2011

    • Author(s)
      Hatano T and Hattori N
    • Publisher
      Rijeka: INTECH
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] Free-water diffusion magnetic resonance imaging under selegiline treatment in Parkinson's disease2024

    • Author(s)
      Takeshige-Amano Haruka、Hatano Taku、Kamagata Koji、Andica Christina、Ogawa Takashi、Shindo Atsuhiko、Uchida Wataru、Sako Wataru、Saiki Shinji、Shimo Yasushi、Oyama Genko、Umemura Atsushi、Ito Masanobu、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 457 Pages: 122883-122883

    • DOI

      10.1016/j.jns.2024.122883

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K11880, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-21H04820
  • [Journal Article] Propagative α-synuclein seeds as serum biomarkers for synucleinopathies.2023

    • Author(s)
      Ayami Okuzumi Taku Hatano Gen Matsumoto Nobutaka Hattori et al
    • Journal Title

      Nature medicine

      Volume: 29 Issue: 6 Pages: 1448-1455

    • DOI

      10.1038/s41591-023-02358-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14785, KAKENHI-PROJECT-21K07283, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-21K07444, KAKENHI-PUBLICLY-22H04651, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-23K24214
  • [Journal Article] Current Status of Telemedicine for Parkinson’s Disease in Japan: A Single-Center Cross-Sectional Questionnaire Survey2022

    • Author(s)
      Ogawa Mayuko、Oyama Genko、Sekimoto Satoko、Hatano Taku、Hattori Nobutaka
    • Journal Title

      Journal of Movement Disorders

      Volume: 15 Issue: 1 Pages: 58-61

    • DOI

      10.14802/jmd.21096

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-21K12711
  • [Journal Article] Genotype-phenotype correlation of Parkinson's disease with PRKN variants2022

    • Author(s)
      Yoshino Hiroyo、Li Yuanzhe、Nishioka Kenya、Daida Kensuke、Hayashida Arisa、Ishiguro Yuta、Yamada Daisuke、Izawa Nana、Nishi Katsunori、Nishikawa Noriko、Oyama Genko、Hatano Taku、Nakamura Shinichiro、Yoritaka Asako、Motoi Yumiko、Funayama Manabu、Hattori Nobutaka
    • Journal Title

      Neurobiology of Aging

      Volume: 114 Pages: 117-128

    • DOI

      10.1016/j.neurobiolaging.2021.12.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07283, KAKENHI-PROJECT-22K07542, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-20K07893
  • [Journal Article] α-Synuclein V15A variant in familial Parkinson's disease exhibits a weaker lipid-binding property.2022

    • Author(s)
      Daida K, Shimonaka S, Shiba-Fukushima K, Ogata J, Yoshino H, Okuzumi A, Hatano T, Motoi Y, Hirunagi T, Katsuno M, Shindou H, Funayama M, Nishioka K, Hattori N, Imai Y.
    • Journal Title

      Mov Disord.

      Volume: 37 Issue: 10 Pages: 2075-2085

    • DOI

      10.1002/mds.29162

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07910, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-22K07542, KAKENHI-PROJECT-20K16160, KAKENHI-PROJECT-22K15649, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-20H03453, KAKENHI-PROJECT-20K07893, KAKENHI-PROJECT-20K21531, KAKENHI-PROJECT-21K19443
  • [Journal Article] Systematic analysis of the molecular mechanisms mediated by coffee in Parkinson’s disease based on network pharmacology approach2021

    • Author(s)
      Li Fangjun、Hatano Taku、Hattori Nobutaka
    • Journal Title

      Journal of Functional Foods

      Volume: 87 Pages: 104764-104764

    • DOI

      10.1016/j.jff.2021.104764

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Journal Article] TLC-based MS Imaging Analysis of Glycosphingolipids and Glycerin Fatty Acid Esters after 1,2-Dichloroethane Washing2021

    • Author(s)
      Matsushita Shoko、Hasegawa Takuma、Hiraoka Marina、Hayashi Aki、Suzuki Yusuke
    • Journal Title

      Anal. Sci.

      Volume: 37 Issue: 11 Pages: 1491-1495

    • DOI

      10.2116/analsci.21C009

    • NAID

      130008114773

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2021-11-10
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Journal Article] Association of Orthostatic Hypotension With Cerebral Atrophy in Patients With Lewy Body Disorders2021

    • Author(s)
      Pilotto A、Hatano T(23/30)et al
    • Journal Title

      Neurology

      Volume: 97 Issue: 8

    • DOI

      10.1212/wnl.0000000000012342

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Journal Article] Comorbid alpha synucleinopathies in idiopathic normal pressure hydrocephalus2021

    • Author(s)
      Sakurai Anri、Tsunemi Taiji、Ishiguro Yuta、Okuzumi Ayami、Hatano Taku、Hattori Nobutaka
    • Journal Title

      Journal of Neurology

      Volume: 269 Issue: 4 Pages: 2022-2029

    • DOI

      10.1007/s00415-021-10778-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-19K16928
  • [Journal Article] Susceptibility of subregions of prefrontal cortex and corpus callosum to damage by high-dose oxytocin-induced labor in male neonatal mice2021

    • Author(s)
      Kitamura Eri、Koike Masato、Hirayama Takashi、Sunabori Takehiko、Kameda Hiroshi、Hioki Hiroyuki、Takeda Satoru、Itakura Atsuo
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 8 Pages: e0256693-e0256693

    • DOI

      10.1371/journal.pone.0256693

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09237, KAKENHI-PROJECT-20K21664, KAKENHI-PROJECT-20K07743, KAKENHI-PROJECT-23K21351
  • [Journal Article] Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease2021

    • Author(s)
      Koinuma Takahiro、Hatano Taku、Kamagata Koji、Andica Christina、Mori Akio、Ogawa Takashi、Takeshige-Amano Haruka、Uchida Wataru、Saiki Shinji、Okuzumi Ayami、Ueno Shin-Ichi、Oji Yutaka、Saito Yuya、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Journal of Parkinson's Disease

      Volume: - Issue: 3 Pages: 1-15

    • DOI

      10.3233/jpd-202495

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17244, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18H02772, KAKENHI-PROJECT-20F20113, KAKENHI-PROJECT-21K07424
  • [Journal Article] Intrajejunal Infusion of Levodopa/Carbidopa for Advanced Parkinson's Disease: A Systematic Review2021

    • Author(s)
      Tsunemi Taiji、Oyama Genko、Saiki Shinji、Hatano Taku、Fukae Jiro、Shimo Yasushi、Hattori Nobutaka
    • Journal Title

      Movement Disorders

      Volume: 36 Issue: 8 Pages: 1759-1771

    • DOI

      10.1002/mds.28595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Reply: <i>PSAP</i> variants in Parkinson’s disease: a large cohort study in Chinese mainland population2021

    • Author(s)
      Oji Yutaka、Hatano Taku、Funayama Manabu、Hattori Nobutaka
    • Journal Title

      Brain

      Volume: 144 Issue: 3 Pages: e26-e26

    • DOI

      10.1093/brain/awaa393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] White matter and nigral alterations in multiple system atrophy-parkinsonian type2021

    • Author(s)
      Ogawa Takashi、Hatano Taku、Kamagata Koji、Andica Christina、Takeshige-Amano Haruka、Uchida Wataru、Kamiyama Daiki、Shimo Yasushi、Oyama Genko、Umemura Atsushi、Iwamuro Hirokazu、Ito Masanobu、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      npj Parkinson's Disease

      Volume: 7 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41531-021-00236-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02772, KAKENHI-PROJECT-20F20113, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-19K17244, KAKENHI-PROJECT-21K20698
  • [Journal Article] α-Synuclein Seeding Assay Using RT-QuIC.2021

    • Author(s)
      Okuzumi Ayami、Hatano Taku、Fukuhara Takeshi、Ueno Shinichi、Nukina Nobuyuki、Imai Yuzuru、Hattori Nobutaka
    • Journal Title

      Methods Mol Biol.

      Volume: 2322 Pages: 3-16

    • DOI

      10.1007/978-1-0716-1495-2_1

    • ISBN
      9781071614945, 9781071614952
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-19K16928
  • [Journal Article] Fiber-specific white matter alterations in early-stage tremor-dominant Parkinson’s disease2021

    • Author(s)
      Andica Christina、Kamagata Koji、Saito Yuya、Uchida Wataru、Fujita Shohei、Hagiwara Akifumi、Akashi Toshiaki、Wada Akihiko、Ogawa Takashi、Hatano Taku、Hattori Nobutaka、Aoki Shigeki
    • Journal Title

      npj Parkinson's Disease

      Volume: 7 Issue: 1 Pages: 1-8

    • DOI

      10.1038/s41531-021-00197-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02772, KAKENHI-PROJECT-20F20113, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-16H06280
  • [Journal Article] Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice2021

    • Author(s)
      Sato Shigeto、Noda Sachiko、Torii Satoru、Amo Taku、Ikeda Aya、Funayama Manabu、Yamaguchi Junji、Fukuda Takahiro、Kondo Hiromi、Tada Norihiro、Arakawa Satoko、Watanabe Masahiko、Uchiyama Yasuo、Shimizu Shigeomi、Hattori Nobutaka
    • Journal Title

      Human Molecular Genetics

      Volume: 30 Issue: 6 Pages: 443-453

    • DOI

      10.1093/hmg/ddab057

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07878, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-17K09769, KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-20K22744, KAKENHI-PLANNED-17H06414, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-21K15198, KAKENHI-PROJECT-20H00467
  • [Journal Article] White matter alterations in Parkinson's disease with levodopa-induced dyskinesia2021

    • Author(s)
      Ogawa Takashi、Hatano Taku、Kamagata Koji、Andica Christina、Takeshige-Amano Haruka、Uchida Wataru、Saito Yuya、Shimo Yasushi、Oyama Genko、Umemura Atsushi、Iwamuro Hirokazu、Ito Masanobu、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Parkinsonism & Related Disorders

      Volume: 90 Pages: 8-14

    • DOI

      10.1016/j.parkreldis.2021.07.021

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H02772, KAKENHI-PROJECT-20F20113, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-19K17244, KAKENHI-PROJECT-21K20698
  • [Journal Article] Overlapping Projections of Neighboring Direct and Indirect Pathway Neostriatal Neurons to Globus Pallidus External Segment2020

    • Author(s)
      Okamoto Shinichiro、Sohn Jaerin、Tanaka Takuma、Takahashi Megumu、Ishida Yoko、Yamauchi Kenta、Koike Masato、Fujiyama Fumino、Hioki Hiroyuki
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 101409-101409

    • DOI

      10.1016/j.isci.2020.101409

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07231, KAKENHI-PROJECT-20K07743, KAKENHI-PROJECT-20K20671, KAKENHI-PROJECT-20K21664, KAKENHI-PUBLICLY-20H05484, KAKENHI-PROJECT-18K14844, KAKENHI-PROJECT-16H03299, KAKENHI-PROJECT-23K20318
  • [Journal Article] Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease2020

    • Author(s)
      Oji Y, Hatano T, Ueno SI, Funayama M, Ishikawa KI, Okuzumi A, Noda S, Sato S, Satake W, Toda T, Li Y, Hino-Takai T, Kakuta S, Tsunemi T, Yoshino H, Nishioka K, Hattori T, Mizutani Y, Mutoh T, Yokochi F, et al.
    • Journal Title

      Brain

      Volume: 143 Issue: 4 Pages: 1190-1205

    • DOI

      10.1093/brain/awaa064

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-19K17019, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-19K08288, KAKENHI-PROJECT-18K07510, KAKENHI-PROJECT-19K23782
  • [Journal Article] Shared Metabolic Profile of Caffeine in Parkinsonian Disorders2020

    • Author(s)
      Takeshige-Amano H, Saiki S, Fujimaki M, Ueno SI, Li Y, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, Tsunemi T, Daida K, Ishiguro Y, Imamichi Y, Nanmo H, Nojiri S, Funayama M, Hattori N.
    • Journal Title

      Mov Disord

      Volume: 35 Pages: 1438-1447

    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Neurocognitive and psychiatric disorders-related axonal degeneration in Parkinson's disease2020

    • Author(s)
      Andica C, Kamagata K, Hatano T, Saito Y, Uchida W, Ogawa T, Takeshige-Amano H, Hagiwara A, Murata S, Oyama G, Shimo Y, Umemura A, Akashi T, Wada A, Kumamaru KK, Hori M, Hattori N, Aoki S.
    • Journal Title

      J Neurosci Res

      Volume: 98 Pages: 936-949

    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Evaluation of white matter microstructure in patients with Parkinson's disease using microscopic fractional anisotropy2020

    • Author(s)
      Ikenouchi Y, Kamagata K, Andica C, Hatano T, Ogawa T, Takeshige-Amano H, Kamiya K, Wada A, Suzuki M, Fujita S, Hagiwara A, Irie R, Hori M, Oyama G, Shimo Y, Umemura A, Hattori N, Aoki S.
    • Journal Title

      Neuroradiology.

      Volume: 62(2) Issue: 2 Pages: 197-203

    • DOI

      10.1007/s00234-019-02301-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Astrocytic 3-Repeat Tau Pathologies in Progressive Supranuclear Palsy2020

    • Author(s)
      Taniguchi D, Takanashi M, Hatano T, Kishikawa S, Shimonaka S, Motoi Y, Yao T, Hattori N.
    • Journal Title

      J Neuropathol Exp Neurol.

      Volume: 79 Pages: 1015-1018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease2020

    • Author(s)
      Yamaguchi A, Ishikawa KI, Inoshita T, Shiba-Fukushima K, Saiki S, Hatano T, Mori A, Oji Y, Okuzumi A, Li Y, Funayama M, Imai Y, Hattori N, Akamatsu W.
    • Journal Title

      Stem Cell Reports

      Volume: 14 Pages: 1060-1075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] MR Biomarkers of Degenerative Brain Disorders Derived From Diffusion Imaging2020

    • Author(s)
      Andica C, Kamagata K, Hatano T, Saito Y, Ogaki K, Hattori N, Aoki S.
    • Journal Title

      J Magn Reson Imaging

      Volume: 52 Pages: 1620-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Ueno SI, Oyama G, Kanai K, Hatano T, Shimo Y, Hattori N. A Retrospective Imaging Evaluation of Presynaptic Dopaminergic Degeneration in Multiple System Atrophy with Levodopa Induced Dyskinesia.2020

    • Author(s)
      Ueno SI, Oyama G, Kanai K, Hatano T, Shimo Y, Hattori N
    • Journal Title

      Tremor Other Hyperkinet Mov (N Y).

      Volume: 10 Issue: 0 Pages: 6-6

    • DOI

      10.5334/tohm.58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Journal Article] Metabolomics‐based identification of metabolic alterations in PARK22019

    • Author(s)
      Okuzumi Ayami、Hatano Taku、Ueno Shin‐Ichi、Ogawa Takashi、Saiki Shinji、Mori Akio、Koinuma Takahiro、Oji Yutaka、Ishikawa Kei‐Ichi、Fujimaki Motoki、Sato Shigeto、Ramamoorthy Sivapriya、Mohney Robert P.、Hattori Nobutaka
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 6 Issue: 3 Pages: 525-536

    • DOI

      10.1002/acn3.724

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-19K22603
  • [Journal Article] Clinical heterogeneity of frontotemporal dementia and Parkinsonism linked to chromosome 17 caused by MAPT N279K mutation in relation to tau positron emission tomography features2019

    • Author(s)
      Ikeda Aya、Shimada Hitoshi、Nishioka Kenya、Takanashi Masashi、Hayashida Arisa、Li Yuanzhe、Yoshino Hiroyo、Funayama Manabu、Ueno Yuji、Hatano Taku、Sahara Naruhiko、Suhara Tetsuya、Higuchi Makoto、Hattori Nobutaka
    • Journal Title

      Movement Disorders

      Volume: 34 Issue: 4 Pages: 568-574

    • DOI

      10.1002/mds.27623

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-16K09700, KAKENHI-PROJECT-19K08003, KAKENHI-PUBLICLY-19H05437, KAKENHI-PROJECT-18H04043
  • [Journal Article] Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy2019

    • Author(s)
      Mori Akio、Ishikawa Kei-Ichi、Saiki Shinji、Hatano Taku、Oji Yutaka、Okuzumi Ayami、Fujimaki Motoki、Koinuma Takahiro、Ueno Shin-Ichi、Imamichi Yoko、Hattori Nobutaka
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 9 Pages: e0223113-e0223113

    • DOI

      10.1371/journal.pone.0223113

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18K15376, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15463
  • [Journal Article] A metabolic profile of polyamines in parkinson disease: A promising biomarker2019

    • Author(s)
      Saiki Shinji、Sasazawa Yukiko、Fujimaki Motoki、Kamagata Koji、Kaga Naoko、Taka Hikari、Li Yuanzhe、Souma Sanae、Hatano Taku、Imamichi Yoko、Furuya Norihiko、Mori Akio、Oji Yutaka、Ueno Shin‐Ichi、Nojiri Shuko、Miura Yoshiki、Ueno Takashi、Funayama Manabu、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Annals of Neurology

      Volume: 86 Issue: 2 Pages: 251-263

    • DOI

      10.1002/ana.25516

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15464
  • [Journal Article] A Randomized Crossover Pilot Study of Telemedicine Delivered via iPads in Parkinson’s Disease2019

    • Author(s)
      Sekimoto Satoko、Oyama Genko、Hatano Taku、Sasaki Fuyuko、Nakamura Ryota、Jo Takayuki、Shimo Yasushi、Hattori Nobutaka
    • Journal Title

      Parkinson's Disease

      Volume: 2019 Pages: 1-7

    • DOI

      10.1155/2019/9403295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16K09675
  • [Journal Article] Pembrolizumab-related systemic myositis involving ocular and hindneck muscles resembling myasthenic gravis: a case report.2019

    • Author(s)
      Kamo H, Hatano T, Kanai K, Aoki N, Kamiyama D, Yokoyama K, Takanashi M, Yamashita Y, Shimo Y, Hattori N.
    • Journal Title

      BMC Neurol.

      Volume: 19(1) Issue: 1 Pages: 184-184

    • DOI

      10.1186/s12883-019-1416-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-19K19951
  • [Journal Article] Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.2019

    • Author(s)
      Mori A, Hatano T, Inoshita T, Shiba-Fukushima K, Koinuma T, Meng H, Kubo SI, Spratt S, Cui C, Yamashita C, Miki Y, Yamamoto K, Hirabayashi T, Murakami M, Takahashi Y, Shindou H, Nonaka T, Hasegawa M, Okuzumi A, Imai Y, Hattori N.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 116(41) Issue: 41 Pages: 20689-20699

    • DOI

      10.1073/pnas.1902958116

    • NAID

      120007132272

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K06978, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18K15376, KAKENHI-PROJECT-19K16928, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-PUBLICLY-18H05025, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-19H03372, KAKENHI-PROJECT-18K15465, KAKENHI-PROJECT-16H02613
  • [Journal Article] Free-Water Imaging in White and Gray Matter in Parkinson's Disease.2019

    • Author(s)
      Andica C, Kamagata K, Hatano T, Saito A, Uchida W, Ogawa T, Takeshige-Amano H, Zalesky A, Wada A, Suzuki M, Hagiwara A, Irie R, Hori M, Kumamaru KK, Oyama G, Shimo Y, Umemura A, Pantelis C, Hattori N, Aoki S.
    • Journal Title

      Cells

      Volume: 8(8) Issue: 12 Pages: 839-839

    • DOI

      10.1007/s00234-019-02279-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-19K17244
  • [Journal Article] Myalgia caused by chronic myositis associated with plasmacytosis: a case report.2018

    • Author(s)
      Hatano T, Takanashi M, Tsuchihashi H, Ueno SI, Hayashida A, Tsukune Y, Kanai K, Shimo Y, Hattori N.
    • Journal Title

      BMC Neurol.

      Volume: 18 Issue: 1 Pages: 112-112

    • DOI

      10.1186/s12883-018-1123-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-16K09675
  • [Journal Article] Randomized, double-blind, multicenter trial of hydrogen water for Parkinson's disease2018

    • Author(s)
      Yoritaka Asako、Ohtsuka Chigumi、Maeda Tetsuya、Hirayama Masaaki、Abe Takashi、Watanabe Hirohisa、Saiki Hidemoto、Oyama Genko、Fukae Jiro、Shimo Yasushi、Hatano Taku、Hattori Nobutaka、et al
    • Journal Title

      Movement Disorders

      Volume: 33 Issue: 9 Pages: 1505-1507

    • DOI

      10.1002/mds.27472

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16K09675
  • [Journal Article] Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment2018

    • Author(s)
      Okuzumi Ayami、Kurosawa Masaru、Hatano Taku、Takanashi Masashi、Nojiri Shuuko、Fukuhara Takeshi、Yamanaka Tomoyuki、Miyazaki Haruko、Yoshinaga Saki、Furukawa Yoshiaki、Shimogori Tomomi、Hattori Nobutaka、Nukina Nobuyuki
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 6 Issue: 1 Pages: 96-96

    • DOI

      10.1186/s40478-018-0587-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0131, KAKENHI-PUBLICLY-17H05705, KAKENHI-PUBLICLY-18H04564, KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-16H04768, KAKENHI-PROJECT-18H02723, KAKENHI-PROJECT-15K06762, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-18H00446, KAKENHI-PROJECT-17KT0130
  • [Journal Article] GCH1 mutations in dopa-responsive dystonia and Parkinson's disease.2018

    • Author(s)
      Yoshino H, Nishioka K, Li Y, Oji Y, Oyama G, Hatano T, Machida Y, Shimo Y, Hayashida A, Ikeda A, Mogushi K, Shibagaki Y, Hosaka A, Iwanaga H, Fujitake J, Ohi T, Miyazaki D, Sekijima Y, Oki M, Kusaka H, Fujimoto KI Ugawa Y, Funayama M, Hattori N.
    • Journal Title

      Journal of Neurology

      Volume: 265(8) Issue: 8 Pages: 1860-1870

    • DOI

      10.1007/s00415-018-8930-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-16K09700
  • [Journal Article] Neuromelanin imaging and midbrain volumetry in progressive supranuclear palsy and Parkinson's disease2018

    • Author(s)
      Taniguchi Daisuke、Hatano Taku、Kamagata Koji、Okuzumi Ayami、Oji Yutaka、Mori Akio、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
    • Journal Title

      Movement Disorders

      Volume: 33 Issue: 9 Pages: 1488-1492

    • DOI

      10.1002/mds.27365

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16K09675
  • [Journal Article] Neurite orientation dispersion and density imaging of the nigrostriatal pathway in Parkinson's disease: Retrograde degeneration observed by tract-profile analysis.2018

    • Author(s)
      Andica C, Kamagata K, Hatano T, Okuzumi A, Saito A, Nakazawa M, Ueda R, Motoi Y, Kamiya K, Suzuki M, Hori M, Kumamaru KK, Hattori N, Aoki S.
    • Journal Title

      Parkinsonism & Related Disorders

      Volume: 18 Pages: 30112-30113

    • DOI

      10.1016/j.parkreldis.2018.02.046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16K19854, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-18H02772
  • [Journal Article] Zonisamide Administration Improves Fatty Acid β-Oxidation in Parkinson's Disease.2018

    • Author(s)
      Ueno SI, Saiki S, Fujimaki M, Takeshige-Amano H, Hatano T, Oyama G, Ishikawa KI, Yamguchi A, Nojiri S, Akamatsu W, Hattori N.
    • Journal Title

      Cells

      Volume: 8 Issue: 1 Pages: 14-14

    • DOI

      10.3390/cells8010014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K15463, KAKENHI-PUBLICLY-17H05706, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09677
  • [Journal Article] Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease.2018

    • Author(s)
      Fujimaki M, Saiki S, Li Y, Kaga N, Taka H, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, Koinuma T, Ueno SI, Imamichi Y, Ueno T, Miura Y, Funayama M, Hattori N.
    • Journal Title

      Neurology.

      Volume: 90 Issue: 5 Pages: 1-8

    • DOI

      10.1212/wnl.0000000000004888

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K01834, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K09700, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-15KK0354, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-18H04043
  • [Journal Article] Depressive symptoms in Parkinson's disease are related to decreased left hippocampal volume: correlation with the 15-item shortened version of the Geriatric Depression Scale.2018

    • Author(s)
      Goto M, Kamagata K, Hatano T, Hattori N, Abe O, Aoki S, Hori M, Gomi T.
    • Journal Title

      Acta Radiologica

      Volume: 59 Issue: 3 Pages: 341-345

    • DOI

      10.1177/0284185117719100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-16H06280
  • [Journal Article] Mitochondrial-Associated Membranes in Parkinson's Disease.2017

    • Author(s)
      Hattori N, Arano T, Hatano T, Mori A, Imai Y.
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 997 Pages: 157-169

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07797
  • [Journal Article] Connectome analysis with diffusion MRI in idiopathic Parkinson's disease: Evaluation using multi-shell, multi-tissue, constrained spherical deconvolution.2017

    • Author(s)
      Kamagata K, Zalesky A, Hatano T, Di Biase MA, El Samad O, Saiki S, Shimoji K, Kumamaru KK, Kamiya K, Hori M, Hattori N, Aoki S, Pantelis C.
    • Journal Title

      Neuroimage Clinical

      Volume: 17 Pages: 518-529

    • DOI

      10.1016/j.nicl.2017.11.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-15K09944, KAKENHI-PROJECT-16K19854
  • [Journal Article] Serum uric acid level is linked to the disease progression rate in male patients with multiple system atrophy.2017

    • Author(s)
      Fukae J, Fujioka S, Yanamoto S, Mori A, Nomi T, Hatano T, Fukuhara K, Ouma S, Hattori N, Tsuboi Y.
    • Journal Title

      Clinical Neurology Neurosurgery

      Volume: 158 Pages: 15-19

    • DOI

      10.1016/j.clineuro.2017.04.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-15K19501
  • [Journal Article] Anhedonia and its correlation with clinical aspects in Parkinson's disease.2017

    • Author(s)
      Nagayama H, Maeda T, Uchiyama T, Hashimoto M, Nomoto N, Kano O, Takahashi T, Terashi H, Hamada S, Hasegawa T, Hatano T, Takahashi T, Baba Y, Sengoku R, Watanabe H, Inoue M, Kadowaki T, Kaneko K, Hideki Shimura H, Kubo S, The Young Japanese Expert Group for Parkinson's Disease and Movement Disorders: YJ-EXPANDS.
    • Journal Title

      Journal of Neurological Science

      Volume: 372 Pages: 403-407

    • DOI

      10.1016/j.jns.2016.10.051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09736
  • [Journal Article] Neuromelanin MRI is useful for monitoring motor complications in Parkinson’s and PARK2 disease.2017

    • Author(s)
      Hatano T, Okuzumi A, Kamagata K, Daida K, Taniguchi D, Hori M, Yoshino H, Aoki S, Hattori N.
    • Journal Title

      Journal of Neural Transmission

      Volume: 124 Issue: 4 Pages: 407-415

    • DOI

      10.1007/s00702-017-1688-9

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Journal Article] Gray Matter Abnormalities in Idiopathic Parkinson's Disease: Evaluation by Diffusional Kurtosis Imaging and Neurite Orientation Dispersion and Density Imaging.2017

    • Author(s)
      Kamagata K, Zalesky A, Hatano T, Ueda R, Di Biase MA, Okuzumi A, Shimoji K, Hori M, Caeyenberghs K, Pantelis C, Hattori N, Aoki S.
    • Journal Title

      Human Brain Mapping

      Volume: in press Issue: 7 Pages: 3704-3722

    • DOI

      10.1002/hbm.23628

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K19854
  • [Journal Article] Neuropathology of PARK14 is identical to idiopathic Parkinson's disease2017

    • Author(s)
      Miki Y, Yoshizawa T, Morohashi S, Seino Y, Kijima H, Shoji M, Mori A, Yamashita C, Hatano T, Hattori N, Wakabayashi K
    • Journal Title

      Mov Disord

      Volume: - Issue: 5 Pages: 35-35

    • DOI

      10.1002/mds.26952

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09306, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K15473, KAKENHI-PROJECT-16K19503, KAKENHI-PROJECT-16K10448
  • [Journal Article] Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson's disease.2017

    • Author(s)
      Saiki S, Hatano T, Fujimaki M, Ishikawa K, Mori A, Oji Y, Okuzumi A, Fukuhara T, Koinuma T, Nagumo M, Furuya N, Nojiri S, Amo T, Yamashiro K, Hattori N.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 7328-7328

    • DOI

      10.1038/s41598-017-06767-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-17K09769, KAKENHI-PLANNED-25111007, KAKENHI-PROJECT-15H04843, KAKENHI-PROJECT-15K09325
  • [Journal Article] Dystonia due to bilateral caudate hemorrhage associated with a COL4A1 mutation.2017

    • Author(s)
      Hatano T, Daida K, Hoshino Y, Li Y, Saitsu H, Matsumoto N, Hattori N.
    • Journal Title

      Parkinsonism and Related Disorders

      Volume: 40 Pages: 80-82

    • DOI

      10.1016/j.parkreldis.2017.04.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09700, KAKENHI-PROJECT-17H01539
  • [Journal Article] Mitochondrial-Associated Membranes in Parkinson's Disease.2017

    • Author(s)
      Hattori N, Arano T, Hatano T, Mori A, Imai Y
    • Journal Title

      Advances in Experimental Medical Biology

      Volume: 997 Pages: 157-169

    • DOI

      10.1007/978-981-10-4567-7_12

    • ISBN
      9789811045660, 9789811045677
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17H04049
  • [Journal Article] The Risk Factors for the Wearing-off Phenomenon in Parkinson&apos;s Disease in Japan: A Cross-sectional, Multicenter Study2017

    • Author(s)
      Ouma S, Fukae J, Fujioka S, Yamamoto S, Hatano T, Yoritaka A, Okuma Y, Kashihara K, Hattori N, Tsuboi Y.
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 15 Pages: 1961-1966

    • DOI

      10.2169/internalmedicine.56.7667

    • NAID

      130005876433

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797
  • [Journal Article] The Direct Cost of Parkinson Disease at Juntendo Medical University Hospital, Japan2016

    • Author(s)
      Yoritaka A, Fukae J, Hatano T, Oda E, Hattori N.
    • Journal Title

      Intern. Med.

      Volume: 55 Issue: 2 Pages: 113-119

    • DOI

      10.2169/internalmedicine.55.4484

    • NAID

      130005119755

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] What is NODDI and what is its role in Parkinson's assessment?2016

    • Author(s)
      Kamagata K, Hatano T, Aoki S.
    • Journal Title

      Expert Rev Neurother

      Volume: 16 Issue: 3 Pages: 241-243

    • DOI

      10.1586/14737175.2016.1142876

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461848, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-26893266, KAKENHI-PROJECT-25461290
  • [Journal Article] Neurite orientation dispersion and density imaging in the substantia nigra in idiopathic Parkinson disease.2016

    • Author(s)
      Kamagata K, Hatano T, Okuzumi A, Motoi Y, Abe O, Shimoji K, Suzuki M, Hori M, Kumamaru KK, Hattori N, Aoki S
    • Journal Title

      European Radiology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics2016

    • Author(s)
      Yoritaka, A.,Abe, T.,Ohtsuka, C.,Maeda, T., Hirayama, M. et al
    • Journal Title

      BMC Neurology

      Volume: 16 Issue: 1 Pages: 66-66

    • DOI

      10.1186/s12883-016-0589-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09350, KAKENHI-PROJECT-15K09360, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-15K19498
  • [Journal Article] Peking university - Juntendo university joint symposium on brain and skin disease. Genetics and Parkinson’s Disease.2016

    • Author(s)
      Hatano T, Hattori N.
    • Journal Title

      Juntendo Medical Journal

      Volume: 62 Pages: 308-310

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Journal Article] A Japanese multicenter survey characterizing pain in Parkinson's disease2016

    • Author(s)
      Kubo SI, Hamada S, Maeda T, Uchiyama T, Hashimoto M, Nomoto N, Kano O, Takahashi T, Terashi H, Takahashi T, Hatano T, Hasegawa T, Baba Y, Sengoku Rl, Watanabe H, Kadowaki T, Inoue M, Kaneko S, Shimura H, Nagayama H
    • Journal Title

      Journal of The Neurological Science

      Volume: 365 Pages: 162-166

    • DOI

      10.1016/j.jns.2016.04.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461263, KAKENHI-PUBLICLY-15H01550, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09736
  • [Journal Article] Re-emergent jaw tremor in Parkinson’s disease.2015

    • Author(s)
      Hatano T, Kurita N, Kobayashi M, Hattori N.
    • Journal Title

      Neurology

      Volume: 85 Issue: 23

    • DOI

      10.1212/wnl.0000000000002189

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] The prevalence and risk factors of cerebral microbleeds in patients with Parkinson's disease.2015

    • Author(s)
      Yamashiro K, Tanaka R, Hoshino Y, et al.
    • Journal Title

      Parkinsonism Relat Disord.

      Volume: 21 Issue: 9 Pages: 1076-1081

    • DOI

      10.1016/j.parkreldis.2015.06.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-25461290
  • [Journal Article] Utility of the Japanese version of the 9-item Wearing-off questionnaire.2015

    • Author(s)
      Fukae J, Higuchi MA, Yanamoto S, Fukuhara K, Tsugawa J, Ouma S, Hatano T, Yoritaka A, Okuma Y, Kahihara K, Hattori N, Tsuboi Y.
    • Journal Title

      Clinical Neurology Neurosurgery

      Volume: 134 Pages: 111-115

    • DOI

      10.1016/j.clineuro.2015.04.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Decreased regional cerebral blood flow in the bilateral thalami and medulla oblongata determined by an easy Z-score (eZIS) analysis of (99m)Tc-ECD-SPECT images in a case of MM2-thalamic-type sporadic Creutzfeldt-Jakob disease.2015

    • Author(s)
      Hayashi Y, Iwasaki Y, Yoshikura N, Asano T, Hatano T, Tatsumi S, Satoh K, Kimura A, Kitamoto T, Yoshida M, Inuzuka T.
    • Journal Title

      J Neurol Sci

      Volume: 358 Issue: 1-2 Pages: 447-452

    • DOI

      10.1016/j.jns.2015.09.356

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08369, KAKENHI-PROJECT-26461290, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-25461290, KAKENHI-PROJECT-26670435, KAKENHI-PROJECT-26305030
  • [Journal Article] Sensory tricks for isolated speech-induced lingual dystonia.2015

    • Author(s)
      Shimo Y, Nishina K, Hatano T, Hattori N.
    • Journal Title

      BMJ case reports

      Volume: - Pages: bcr2014208272-bcr2014208272

    • DOI

      10.1136/bcr-2014-208272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Identification of novel biomarkers for Parkinson's disease by metabolomic technologies.2015

    • Author(s)
      Hatano T, Saiki S, Okuzumi A, Mohney RP, Hattori N.
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: jnnp-2014 Issue: 3 Pages: 2014-309676

    • DOI

      10.1136/jnnp-2014-309676

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-ORGANIZER-25111001, KAKENHI-PROJECT-25461290, KAKENHI-PLANNED-25111007
  • [Journal Article] Target- and input-dependent organization of AMPA and NMDA receptors in synaptic connections of the cochlear nucleus2015

    • Author(s)
      Rubio ME, Fukazawa Y, Kamasawa N, Clarkson C, Molnar E, Shigemoto R
    • Journal Title

      J Comp Neurol

      Volume: 588 Pages: 29-35

    • DOI

      10.1016/j.neulet.2014.12.052

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24659431, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25460276, KAKENHI-PROJECT-25461290, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25860711, KAKENHI-PUBLICLY-26111519, KAKENHI-PROJECT-25461279, KAKENHI-PROJECT-26860188
  • [Journal Article] Lipid rafts involvement in the pathogenesis of Parkinso’s disease.2015

    • Author(s)
      Kubo SI, Hatano T, Hattori N.
    • Journal Title

      Front Biosci (Landmark Ed).

      Volume: 20 Pages: 263-279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Identification of a Japanese family with LRRK2 p.R1441G-related Parkinson's disease.2014

    • Author(s)
      Hatano T, Funayama M, Kubo S, Mata IF, Oji Y, Mori A, Zabetian CP, Waldherr SM, Yoshino H, Oyama G, Shimo Y, Fujimoto K, Oshima H, Kunii Y, Yabe H, Mizuno Y, Hattori N.
    • Journal Title

      Neurobiol Aging.

      Volume: Nov;35(11) Issue: 11 Pages: 2656.e17-2656.e23

    • DOI

      10.1016/j.neurobiolaging.2014.05.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-24390224, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461290, KAKENHI-PROJECT-25461291
  • [Journal Article] An exploratory study of the efficacy and safety of yokukansan for neuropsychiatric symptoms in patients with Parkinson's disease.2014

    • Author(s)
      Hatano T, Hattori N, Kawanabe T, Terayama Y, Suzuki N, Iwasaki Y, Fujioka T; Yokukansan Parkinson’s Disease Study Group
    • Journal Title

      Journal of Neural Transmission

      Volume: 121 Issue: 3 Pages: 275-281

    • DOI

      10.1007/s00702-013-1105-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Ophthalmic nerve hypertrophy in Chronic Inflammatory Demyelinating Polyradiculoneuropathy.2014

    • Author(s)
      Okuzumi A, Hatano T, Nakahara T, Yokoyama K, Hattori N.
    • Journal Title

      Neurology

      Volume: 82 Issue: 17 Pages: 1566-1567

    • DOI

      10.1212/wnl.0000000000000362

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Rhinorrhea in Parkinson's disease: a consecutive multicenter study in Japan.2014

    • Author(s)
      Kano O, Yoshioka M, Nagayama H, Hamada S, Maeda T, Hasegawa T, Kadowaki T, Sengoku R, Terashi H, Hatano T, Nomoto N, Inoue M, Shimura H, Takahashi T, Uchiyama T, Watanabe H, Kaneko S, Takahashi T, Baba Y, Kubo S; Young Japanese Expert Group for Parkinson's Disease and Movement Disorders: YJ-EXPANDS.
    • Journal Title

      Journal of Neurological Science

      Volume: 343 Issue: 1-2 Pages: 88-90

    • DOI

      10.1016/j.jns.2014.05.039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790897, KAKENHI-PROJECT-25461290, KAKENHI-PROJECT-26461263
  • [Journal Article] Quantitative evaluation of electroconvulsive therapy for Parkinson’s disease with refractory psychiatric symptoms.2014

    • Author(s)
      Nishioka K, Tanaka R, Shimura H, Hirano K, Hatano T, Miyakawa K, Arai H, Hattori N, Urabe T.
    • Journal Title

      Journal of Neural Transmission

      Volume: 121 Issue: 11 Pages: 1405-1410

    • DOI

      10.1007/s00702-014-1212-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290, KAKENHI-PROJECT-25860726
  • [Journal Article] A preliminary diffusional kurtosis imaging study of Parkinson disease: comparison with conventional diffusion tensor imaging.2014

    • Author(s)
      Kamagata K, Tomiyama H, Hatano T, Motoi Y, Abe O, Shimoji K, Kamiya K, Suzuki M, Hori M, Yoshida M, Hattori N, Aoki S.
    • Journal Title

      Neuroradiology

      Volume: 56 Issue: 3 Pages: 251-258

    • DOI

      10.1007/s00234-014-1327-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591787, KAKENHI-PROJECT-25461290, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25861126
  • [Journal Article] Motor and non-motor symptoms of 1453 patients with Parkinson’s disease: any relationship with the cumulative doses of anti-parkinsonian medications?2014

    • Author(s)
      Yoritaka A, Shimo Y, Takanashi M, Fukae J, Hatano T, Nakahara T, Miyamoto N, Urabe T, Hattori N.
    • Journal Title

      Journal of Neurological Disorders & Stroke

      Volume: 2 Pages: 1042-1042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Serum uric acid concentration is linked to wearing-off fluctuation in Japanese Parkinson’s disease patients.2014

    • Author(s)
      Fukae J, Ishikawa KI, Hatano T, Yoritaka A, Takanashi M, Shimo Y, Tsugawa J, Tsuboi Y, Hattori N.
    • Journal Title

      Journal of Parkinson Disease

      Volume: 4 Issue: 3 Pages: 499-505

    • DOI

      10.3233/jpd-140353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Can parkin be a target for future treatment of Parkinson's disease?2013

    • Author(s)
      Kubo S, Hatano T, Takanashi M, Hattori N
    • Journal Title

      Expert Opinion Therapeutic Targets

      Volume: 17 Issue: 10 Pages: 1133-1144

    • DOI

      10.1517/14728222.2013.827173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Motor and non-motor symptoms of 1453 patients with Parkinson's disease: prevalence and risks.2013

    • Author(s)
      Yoritaka A, Shimo Y, Takanashi M, Fukae J, Hatano T, Nakahara T, Miyamato N, Urabe T, Mori H, Hattori N
    • Journal Title

      Parkinsonism and Related Disorders

      Volume: 19 Issue: 8 Pages: 725-731

    • DOI

      10.1016/j.parkreldis.2013.04.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] VPS35 Mutation in Japanese Patients with Typical Parkinson’s Disease2013

    • Author(s)
      Ando M, Kokubo Y.
    • Journal Title

      Movement Disorders

      Volume: 15;27(11) Issue: 11 Pages: 175-182

    • DOI

      10.1002/mds.25145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21256005, KAKENHI-PROJECT-23700389, KAKENHI-PROJECT-23791003, KAKENHI-PROJECT-24390224, KAKENHI-PUBLICLY-23129506
  • [Journal Article] Lateral and dorsal column hyperintensity on magnetic resonance imaging in a patient with myelopathy associated with intrathecal chemotherapy.2013

    • Author(s)
      Saito F, Hatano T, Hori M, Kawamura M, Sasaki M, Aoki S, Hattori N
    • Journal Title

      Case Report in Neurology

      Volume: 5 Issue: 2 Pages: 110-115

    • DOI

      10.1159/000351848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Journal Article] Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein.2012

    • Author(s)
      Sekigawa A
    • Journal Title

      Mol Brain.

      Volume: 5 Issue: 1 Pages: 34-34

    • DOI

      10.1186/1756-6606-5-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659462, KAKENHI-PROJECT-23700389, KAKENHI-PUBLICLY-24111555
  • [Journal Article] PINK1 autophosphorylation facilitates Parkin recruitment ot mitochondria: new insight in the mechanisms of quality control for mitochondria in young-onset Parkinosn's disease2012

    • Author(s)
      Hatano T.
    • Journal Title

      Mov Disord

      Volume: 27 Pages: 1613-1613

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] Young Japanese Expert Group for Parkison's Disease and Movement Disorders: YJ-EXPANDS. Validity and reliability assessment of a Japanese version of the Snaith-Hamilton pleasure scale2012

    • Author(s)
      Nagayama H, Kubo S, Hatano T, Hamada S, Maeda T, Hasegawa T, Kadowaki T, Terashi H, Yoshioka M, Nomoto N, Kano O, Inoue M, Shimura H, Takahashi T, Uchiyama T, Watanabe H, Kaneko S, Takahashi T, Baba Y
    • Journal Title

      Intern Med

      Volume: 51 Pages: 865-9

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] LRRK2 I2020T mutation is associated with tau pathology2012

    • Author(s)
      Ujiie S
    • Journal Title

      Parkinsonism and Related Disorders

      Volume: 18 Issue: 7 Pages: 819-823

    • DOI

      10.1016/j.parkreldis.2012.03.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240039, KAKENHI-PROJECT-22500325, KAKENHI-PROJECT-23700389, KAKENHI-PLANNED-23111003
  • [Journal Article] LRRK2 I2020T mutation is associated with tau pathology2012

    • Author(s)
      Ujiie S, Hatano T, Kubo SI, Imai S, Sato S, Uchihara T, Yagishita S, Hasegawa K, Kowa H, Sakai F, Hattori N.
    • Journal Title

      Parkinsonism Relat Disord

      Volume: 18 Pages: 819-23

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] Urinary homocysteic Acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients2012

    • Author(s)
      Hasegawa T, Ichiba M, Matsumoto SE, Kasanuki K, Hatano T, Fujishiro H, Iseki E, Hattori N, Yamada T, Tabira T.
    • Journal Title

      J Alzheimers Dis

      Volume: 31(1) Pages: 59-64

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients.2012

    • Author(s)
      Hasegawa T, Hatano T (5番目)
    • Journal Title

      Journal of Alzheimers Disease

      Volume: 1 Issue: 1 Pages: 59-64

    • DOI

      10.3233/jad-2012-120022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700389, KAKENHI-PROJECT-24791232
  • [Journal Article] Levodopa-responsive Parkinsonism following bilateral putaminal hemorrhages2012

    • Author(s)
      Hatano T, Kubo SI, Niijima-Ishii Y, Hattori N, Sugita Y
    • Journal Title

      Parkinosnism Relat Disord

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] VPS35 mutation in Japanese patients with typical Parkinos's disease2012

    • Author(s)
      Ando M, Funayama M, Li Y, Kashihara K, Murakami Y, Ishizu N, Toyoda C, Noguchi K, Hashimoto T, Nakano N, Sasaki R, Kokubo Y, Kuzuhara S, Ogaki K, Yamashita C, Yoshino H, Hatano T, Tomiyama H, Hattori N.
    • Journal Title

      Mov Disord

      Volume: 27 Pages: 1413-7

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] DJ-1 associates with synaptic membranes2011

    • Author(s)
      Usami Y, Hatano T, Imai S, Kubo S, Sato S, Saiki S, Fujioka Y, Ohba Y, Sato F, Funayama M, Eguchi H, Shiba K, Ariga H, Shen J, Hattori N
    • Journal Title

      Neurobiol of Dis

      Volume: 43 Pages: 651-62

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] DJ-1 associates with synaptic membranes2011

    • Author(s)
      Yukiko Usami, Taku Hatano, Satoshi Imai, Shin-ichiro Kubo, Shigeto Sato, Shinji Saiki, Yoichiro Fujioka, Yusuke Ohba, Fumiaki Sato, Manabu Funayama. Hiroto Eguchi, Kaori Shiba, Hiroyoshi Ariga, Jie Shen, Nobutaka Hattori
    • Journal Title

      Neurobiology of Disease

      Volume: 43 Issue: 3 Pages: 651-662

    • DOI

      10.1016/j.nbd.2011.05.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04616, KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790829, KAKENHI-PUBLICLY-23114501, KAKENHI-PUBLICLY-23129506, KAKENHI-PROJECT-23390090, KAKENHI-PROJECT-23659196, KAKENHI-PROJECT-23700389
  • [Journal Article] Pramipexole reduces the prevalence of fatigue in patients with Parkinson's disease2011

    • Author(s)
      Morita A, Okuma Y, Kamei S, Yoshii F, Yamamoto T, Hashimoto S, Utusmi H, Hatano T, Hattori N, Matsumura M, Takahashi K, Nogawa S, Watanabe Y, Miyamoto M, Hirata K.
    • Journal Title

      Intern Med

      Volume: 50 Pages: 2163-8

    • NAID

      130001087898

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] The effect of Ndrg2 expression on astroglial activation.2011

    • Author(s)
      Takeichi T, Takarada-Iemata M, Hashida K, Sudo H, Okuda T, Kokame K, Hatano T, Takanashi M, Funabe S, Hattori N, Kitamura O, Kitao Y, Hori O.
    • Journal Title

      Neurochemistry International

      Volume: 59 Pages: 21-27

    • NAID

      120003221535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] Atypical Miller Fisher syndrome assocaited with glutamate receptor antibodies2011

    • Author(s)
      Hatano T, Shimada Y, Kono A, Kubo S, Yokoyama K, Yoritaka A, Nakahara T, Takahashi Y, Hattori N
    • Journal Title

      BMJ Case Rep 2011

      Volume: 2011 Pages: bcr0820103228-bcr0820103228

    • DOI

      10.1136/bcr.08.2010.3228

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] The effect of Ndrg2 expression on astroglial activation2011

    • Author(s)
      Takeichi T, Takarada-Iemata M, Hashida K, Sudo H, Okuda T, Kokame K, Hatano T, Takanashi M, Funabe S, Hattori N, Kitamura O, Kitao Y, Hori O
    • Journal Title

      Neurochem International

      Volume: 59 Pages: 21-7

    • NAID

      120003221535

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] Pramipexole Reduces the Prevalence of Fatigue in Patients with Parkinson's Disease2011

    • Author(s)
      Morita A
    • Journal Title

      Intern. Med.

      Volume: 50 Issue: 19 Pages: 2163-2168

    • DOI

      10.2169/internalmedicine.50.5456

    • NAID

      130001087898

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390272, KAKENHI-PLANNED-23111003, KAKENHI-PROJECT-23700389
  • [Journal Article] A novel protein degradation system in young-onset Parkinosn's disease: mitophagy is a therapeutic target as a quality control for damaged mitochondria2011

    • Author(s)
      Hatano T
    • Journal Title

      Mov Disord

      Volume: 26 Pages: 773-773

    • Data Source
      KAKENHI-PROJECT-23700389
  • [Journal Article] PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.2010

    • Author(s)
      Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N
    • Journal Title

      FEBS Lett 584(6)

      Pages: 1073-9

    • Data Source
      KAKENHI-PROJECT-20023028
  • [Journal Article] PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.2010

    • Author(s)
      Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N.
    • Journal Title

      FEBS Lett 584 Joint first authors

      Pages: 1073-1079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Journal Article] Unmet needs of patients with Parkinson's disease: interview survey of patients and caregivers2009

    • Author(s)
      Hatano T, Kubo S-I, Shimo Y, Nishioka K, Hattori N.
    • Journal Title

      J Int Med Res 37(3)

      Pages: 717-726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] Pathogenesis of familial Parkinson's disease: New insights based on monogenic forms of Parkinson's disease2009

    • Author(s)
      Hatano T, Kubo S-I, Sato S, Hattori N.
    • Journal Title

      J Neurochem (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] Fatigue in Japanese patients with Parkinson ' s disease: A study using Parkinson fatigue scale2009

    • Author(s)
      Okuma Y, Kamei S, Morita A, YoshiiF, Yamamoto T, Hashimoto S, Utsumi H, Hatano T, Hattori N, Matsumura M, Takahashi K, Nogawa S, Watanabe Y, Miyamoto T, Miyamoto M, Hirata K.
    • Journal Title

      Mov Disord. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] ミトコンドリアと神経変性疾患2008

    • Author(s)
      波田野琢, 服部信孝
    • Journal Title

      脳と精神の医学 19

      Pages: 81-89

    • NAID

      10026932917

    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] LRRK2 regulates synaptic vesicle endocytosis2008

    • Author(s)
      Shin N, Jeong H, Know J, Heo HY, Know JJ, Yun HJ, Kim CH, Tong Y, Shen J, Hatano T, Hattori N, Kim KS, Chang S, Seol W.
    • Journal Title

      Exp Cell Res 314(10)

      Pages: 2055-2065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] 家族性パーキンソン病2008

    • Author(s)
      波田野琢, 服部信孝
    • Journal Title

      成人病と生活習慣病 38

      Pages: 893-899

    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] Progress in the pathogenesis and genetics of Parkinson ' s disease2008

    • Author(s)
      Mizuno Y, Hattori N, Kubo S-I, Sato S, Nishioka K, Hatano T, Tomiyama H, Funayama M, Machida Y, Mochizuki H.
    • Journal Title

      Philos Trans R Soc Lond B Biol Sci 363(1500)

      Pages: 2215-2227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] パーキンソン病を理解するための最新基礎知識(解説/特集)2008

    • Author(s)
      波田野琢
    • Journal Title

      医学のあゆみ 225

      Pages: 460-466

    • Data Source
      KAKENHI-PROJECT-20790624
  • [Journal Article] The frequency of cardiac valvular regurgitation in Parkinson's disease2008

    • Author(s)
      Yamashiro K, Komine-Kobayashi M, Hatano T, Urabe T, Mochiuki H, Hattori N, Iwama Y, Daida H, Sakai M, Nakayama T, Mizuno Y.
    • Journal Title

      Mov Disord 23(7)

      Pages: 935-941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Patent] パーキンソン病診断薬及びモデル動物2018

    • Inventor(s)
      服部 信孝、王子 悠、波田野 琢
    • Industrial Property Rights Holder
      服部 信孝、王子 悠、波田野 琢
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-200039
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Patent] α―シヌクレイノパチーの診断2018

    • Inventor(s)
      服部 信孝、波田野 琢、奥住 文美、上野 真一
    • Industrial Property Rights Holder
      服部 信孝、波田野 琢、奥住 文美、上野 真一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-159694
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Challenges and Future Prospects for Diagnostic Imaging and Biomarkers of Parkinson's Disease and Atypical Parkinsonism2023

    • Author(s)
      Hatano T, Okuzumi A, Takeshige-Amano H, Ogawa T, Hattori N
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Reproducibility of serum alpha-synuclein seed detection method、優秀ポスター賞2023

    • Author(s)
      奥住文美、波田野 琢、松本 弦、貫名信行、服部信孝
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Pathogenesis of α-synucleinopathy2023

    • Author(s)
      Hatanot T, Okuzumi A, Hattori N.
    • Organizer
      UK-JP Neuroscience Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Alpha Synuclein Aggregation and Propagation2023

    • Author(s)
      Hatano T, Okuzumi A, Hattori N.
    • Organizer
      10th Singapore International Parkinson Disease and Movement Disorders Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] α-synuclein:Biomarker of Synucleinopathy2023

    • Author(s)
      Hatano T, Okuzumi A, Hattori N.
    • Organizer
      MDS-AOS Basic Summer School
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] A-synuclein aggregation and proteomics in Parkinson's disease and Multiple system atrophy, ポスター2023

    • Author(s)
      上野真一、波田野 琢、奥住文美、斉木臣二、小田吉哉、服部信孝
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] 画像およびバイオマーカーを用いたパーキンソン病と非典型的パーキンソニズムの鑑別と病態理解、シンポジウム2023

    • Author(s)
      波田野 琢、服部信孝
    • Organizer
      第64回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Propagative α-synuclein seeds as serum biomarkers in synucleinopathies2023

    • Author(s)
      Hatano T, Okuzumi A, Hattori N
    • Organizer
      18th annual GEoPD meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Identification of seral disease-specific alpha-synuclein seeds using IP-RT-QuIC.2022

    • Author(s)
      Okuzumi A, Hatano T, Matsumoto G, Nukina N, Hattori N.
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] The pathomechanisms of Levodopa-Induced Dyskinesia in Parkinson’s disease.2022

    • Author(s)
      Taku Hatano, Takashi Ogawa, Nobutaka Hattori
    • Organizer
      第95回日本薬理学会総会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] PARK24プロサポシン遺伝子変異のiPSCドパミン神経細胞におけるCOMTの増加 (ポスター(英語))2022

    • Author(s)
      下島健太郎、王子 悠、若盛 亮、野中里沙、石川景一、上野真一、奥住文美、波田野 琢、赤松和土、服部信孝
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Identification of seral disease-specific alpha-synuclein seeds using IP-RT-QuIC. 口演2022

    • Author(s)
      奥住文美、波田野 琢、松本 弦、貫名信行、服部信孝
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] IP/RT-QuICによるシヌクレイノパチー疾患特異的血液アルファシヌクレインシードの検出2022

    • Author(s)
      奥住文美、波田野琢、服部信孝、他
    • Organizer
      第119回日本内科学会総会・講演会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] PD-linked prosaposin gene mutation affects intracellular trafficking and secretion of prosaposin. ポスター(英語)2022

    • Author(s)
      若盛 亮、王子 悠、波田野 琢、下島健太郎、奥住文美、上野真一、野中里紗、石川景一、赤松和土、服部信孝
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Decrease of GM1 ganglioside and LAMP2 in PARK24-linked prosaposin gene mutation. 口演2022

    • Author(s)
      王子 悠、波田野 琢、池田和貴、野中里紗、石川景一、若盛 亮、下島健太郎、上野真一、奥住文美、赤松和土、服部信孝
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] パーキンソン病における血中α-シヌクレインとプロテオミクスの検. ポスター2022

    • Author(s)
      上野真一、波田野琢、奥住文美、小田吉哉、服部信孝
    • Organizer
      第16回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] 遺伝子からアプローチするパーキンソン病の病態解明. プレナリーセッション2022

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第16回パーキンソン病・運動障害疾患コングレス
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Mechanisms of α-synuclein aggregation and potential treatment strategy for PD2022

    • Author(s)
      Taku Hatano, Akio Mori, Yutaka Oji, Ayami Okuzumi and Nobutaka Hattori
    • Organizer
      RIKEN Symposium ~ Mechanistic Insights into Neurodegenerative Disorders ~
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Correlation between serum α-synuclein aggregation and proteomics in Parkinson's disease. ポスター(英語)2022

    • Author(s)
      上野真一、波田野 琢、奥住文美、小田吉哉、服部信孝
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] IP/RT-QuICによるシヌクレノパチー疾患特異的血液アルファシヌクレインシードの検出. ポスター2022

    • Author(s)
      奥住文美、波田野琢、松本弦、貫名信行、服部信孝
    • Organizer
      第16回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Analysis of α-synuclein aggregation and proteomics in Parkinson’s disease.2022

    • Author(s)
      Ueno SI, Hatano T, Okuzumi A, Oda Y, Hattori N.
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] プロサポシン遺伝子変異によりゴルジ異常の検討. ポスター2022

    • Author(s)
      王子悠、下島健太郎、野中里紗、若盛亮、石川景一、波田野琢、赤松和土、服部信孝
    • Organizer
      第16回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Metabolite Biomarkers Parkinson Disease and Parkinsonism2021

    • Author(s)
      Taku Hatano, Nobutaka Hattori
    • Organizer
      9th Singapore International Parkinson Disease and Movement Disorders Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] 腸管からパーキンソン病を考える2021

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第74回日本自律神経学会総会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Mechanisms of α-synuclein aggregation and potential treatment strategy for PD2021

    • Author(s)
      Taku Hatano, Nobutaka Hattori
    • Organizer
      MDS-AOS Basic Science Summer School
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] 脂質代謝異常とαシヌクレイン凝集(シンポジウム)2021

    • Author(s)
      王子 悠、波田野 琢、上野真一、舩山 学、石川景一、奥住文美、野田幸子、佐藤栄人、李 元哲、日野知子[高井]、角田宗一郎、常深泰司、吉野浩代、西岡健弥、内山安男、赤松和土、Wu Yih-Ru、松田純子、服部信孝
    • Organizer
      第14回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] Structure and propagation of aggregated proteins、Neuroscience Frontier Symposium、シンポジウム2021

    • Author(s)
      奥住文美、波田野 琢、貫名信行、服部信孝
    • Organizer
      第62回日本神経学会学術大会、2021年5月21日、国立京都国際会館、京都
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] 生体内のαシヌクレインタンパク質が見たい!2021

    • Author(s)
      4.波田野琢、服部信孝
    • Organizer
      第61回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] パーキンソン病とPhysical Activity Scale in the Elderlyとの関連についての検討(ポスター)2021

    • Author(s)
      若盛 亮、王子 悠、小川 崇、竹重遥香、上野真一、波田野 琢、服部信孝
    • Organizer
      第62回日本神経学会学術大会、2021年5月20日、国立京都国際会館、京都
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] Lipid Metabolism and α-synuclein aggregation2021

    • Author(s)
      Taku Hatano and Nobutaka Hattori
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] 脂質代謝異常とαシヌクレイン凝集Selective vulnerability of alpha-synuclein-related neurodegeneration -beyond proteinopathy and propagation、シンポジウム2021

    • Author(s)
      波田野 琢、王子 悠、森 聡生、服部信孝
    • Organizer
      第62回日本神経学会学術大会、2021年5月19日、国立京都国際会館、京都
    • Data Source
      KAKENHI-PROJECT-21H04820
  • [Presentation] 脂質代謝異常とαシヌクレイン凝集Selective vulnerability of alpha-synuclein-related neurodegeneration -beyond proteinopathy and propagation(シンポジウム)2021

    • Author(s)
      波田野 琢、王子 悠、森 聡生、服部信孝
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] Searching for novel biomarkers in Parkinson’s disease.2021

    • Author(s)
      Taku Hatano, Ayami Okuzumi, and Nobutaka Hattori
    • Organizer
      The 2021 Annual meeting of the Korean Society of Neurodegenerative Disease (KSND) 30th
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Updates in Neuroimaging for Parkinson Disease and Related Disorders2021

    • Author(s)
      Taku Hatano, Nobutaka Hattori
    • Organizer
      9th Singapore International Parkinson Disease and Movement Disorders Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07424
  • [Presentation] Structure and propagation of aggregated proteins, Neuroscience Frontier Symposium(シンポジウム))2021

    • Author(s)
      奥住文美、波田野 琢、貫名信行、服部信孝
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] White matter alterations in Multiple System Atrophy-parkinsonian variant2020

    • Author(s)
      小川 崇、波田野 琢、竹重遙香、鎌形康司、Christina Andica、内田 航、濃沼崇博、中村亮太、岩室宏一、大山彦光、下 泰司、梅村 淳、伊藤賢伸、青木茂樹、服部信孝
    • Organizer
      第61回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] パーキンソン病・PARK2患者におけるバイオマーカーとしての酸化型アルブミン.2019

    • Author(s)
      上野真一, 波田野琢, 奥住文美, 斉木臣二, 王子悠, 森聡生, 濃沼崇博, 藤巻基紀, 安川惠子, 矢冨裕, 池田均, 服部信孝.
    • Organizer
      第13回パーキンソン病・運動障害学会コングレス
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] Will mobile health technology improve management?2019

    • Author(s)
      Taku Hatano, Nobutaka Hattori
    • Organizer
      “Takamatsu” International Symposium for PD & MD
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Synaptic dysfunction in a Drosophila model of PARK142019

    • Author(s)
      Hatano T, Mori A, Inoshita T, Fukushima-Shiba K, Koinuma T, Yamashita C, Imai Y, Hattori N.
    • Organizer
      23rd International Congress of Parkinson’s Disease and Movement Disorders. Sep 22-26, Nice, France.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] 一般診療で覚えておきたい神経疾患2019

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第6回中央区医師会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Serum non-mercaptalbumin as a potential biomarker in Parkinson’s disease and related disorders2019

    • Author(s)
      Ueno SI, Hatano T, Okuzumi A, Saiki S, Oji Y, Mori A, Koinuma T, Fujimaki M, Takeshige-Amano H, Yasukawa K, Yatomi Y, Ikeda H, Hattori N.
    • Organizer
      23rd International Congress of Parkinson’s Disease and Movement Disorders. Sep 22-26, Nice, France.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22603
  • [Presentation] DATイメージングを用いたパーキンソニズムの診断2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第37回日本認知症学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] 神経化学からみた神経疾患 -ベンチとベットサイドの間-2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第40回日本生物学的精神医学会・第61回日本神経化学会大会 合同年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] 不随意運動にも色々ある ―診断と鑑別について―2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第36回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] パーキンソン病の治療(薬物療法と生活のヒント)2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第9回パーキンソン病市民公開講座(青森)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] 実地に沿ったパーキンソン病診療のノウハウ;エキスパートはどう診療するのか?2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      第59回日本神経学会総会; 第15回生涯教育セミナー「Hands-on」プログラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] 非運動症状について2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      会津パーキンソン病市民公開講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] パーキンソン病の理解・基礎知識2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      MDSJ第8回PDナース研修会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] パーキンソニズムの脳循環代謝と脳内ネットワーク 臨床診断と脳循環2018

    • Author(s)
      波田野 琢、服部 信孝
    • Organizer
      第61回日本脳循環代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Neuromelanin Imaging and Midbrain Volumetry in Progressive Supranuclear Palsy and Parkinson’s Disease2018

    • Author(s)
      Taku Hatano, Daisuke Taniguchi, Koji Kamagata, Masaaki Hori, Shigeki Aoki, Nobutaka Hattori
    • Organizer
      16th Asia Oceanian Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] パーキンソン病の治療と日常生活(薬物治療と生活のヒント)2018

    • Author(s)
      波田野琢、服部信孝
    • Organizer
      パーキンソン病市民公開講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Comprehensive metabolome analysis of serum of parkin knockout mice.2017

    • Author(s)
      Hatano T, Okuzumi A, Saiki S, Sato S, Hattori N
    • Organizer
      23rd World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Serum non-mercaptoalbumin in patients with Parkinson's disease.2017

    • Author(s)
      Ueno S, Hatano T, Oji Y, Saiki S, Ikeda H, Hattori N
    • Organizer
      23rd World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] パーキンソン病における早期診断マーカーとしての酸化型・還元型アルブミン測定2017

    • Author(s)
      上野真一、波田野琢、王子悠、斉木臣二、奥住文美、池田均、服部信孝
    • Organizer
      第11回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] シンポジウム「パーキンソン病 : 新規の診療ガイドライン」パーキンソン病の運動症状の治療方針2017

    • Author(s)
      波田野琢、下泰司、武田篤、服部信孝
    • Organizer
      第35回 日本神経治療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Comprehensive metabolomic analysis of serum of PARK2 patients.2017

    • Author(s)
      Okuzumi A, Hatano T, Saiki S, Hattori N.
    • Organizer
      23rd World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] マウス脳における脳梁離断を用いた線維状αsynucleinの伝播経路の検討2017

    • Author(s)
      奥住文美、波田野琢、黒澤大、山中智行、宮崎晴子、古川良明、服部信孝、貫名信行
    • Organizer
      第11回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Dystonia due to bilateral caudate hemorrhage associated with a COL4A1 mutation.2017

    • Author(s)
      Hatano T, Daida K, Hoshino Y, Li Y, Saitsu H, Matsumoto N, Hattori N
    • Organizer
      International Congress of Parkinson’s Disease and Movement Disorders
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] PLA2G6変異により脳脂質構成異常を起こし、α-シヌクレイン凝集を加速させる2017

    • Author(s)
      森聡生、濃沼崇博、井下強、山下力、波田野琢、今居譲、服部信孝
    • Organizer
      第11回パーキンソン病・運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Symposium; Fission, Fusion, Autophagy-2 Mitochondrial dysfunction and Parkinson’s disease2016

    • Author(s)
      Hatano T
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 16th Conference of Japanese Society of Mitochondrial Research and Medicine [J-mit]
    • Place of Presentation
      東京
    • Year and Date
      2016-10-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Neuromelanin-imagingを用いたパーキンソン病とPARK2の解析2016

    • Author(s)
      波田野 琢, 鎌形 康司, 奥住 文美, 代田 健祐, 谷口 大祐, 堀 正明, 吉野 浩代, 青木 茂樹, 服部 信孝
    • Organizer
      第10回 パーキンソン病・運動障害疾患コングレス
    • Place of Presentation
      京都
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] ニューロメラニンイメージングを用いた孤発性パーキンソン病およびPARK2の臨床症状に関する解析2016

    • Author(s)
      波田野 琢, 鎌形 康二, 奥住 文美, 吉野 浩代, 堀 正明, 青木 茂樹, 服部 信孝
    • Organizer
      第34回日本神経治療学総会
    • Place of Presentation
      鳥取
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Prognostic Factors of Motor Symptoms in Parkinson’s Disease Using Neuroimaging2016

    • Author(s)
      A. Okuzumi, T. Hatano, K. Kamagata, M. Hori, S. Aoki, N. Hattori
    • Organizer
      20th International Congress of Parkinson’s disease and Movement Disorders.
    • Place of Presentation
      ベルリン
    • Year and Date
      2016-06-19
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Neuromelanin imaging is useful for monitoring disease progression in Parkinson’s disease and PARK22016

    • Author(s)
      Daida, D., T. Hatano, A. Okuzumi, K. Kamagata, K. Taniguchi, M. Hori, H. Yoshino, S. Aoki, N. Hattori
    • Organizer
      第57回日本神経学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] シンポジウム11パーキンソン病の在宅医療と緩和ケア 在宅における薬剤療法の実際2016

    • Author(s)
      波田野 琢, 石垣 泰則, 服部 信孝
    • Organizer
      第18回日本在宅医学会大会 第21回日本在宅ケア学会学術集会合同大会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Prognostic Factors of Motor Symptoms in Parkinson’s Disease Using Neuroimaging2016

    • Author(s)
      A. Okuzumi, T. Hatano, K. Kamagata, M. Hori, S. Aoki, N. Hattori
    • Organizer
      第57回日本神経学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Neuromelanin imaging is useful for monitoring disease progression in Parkinson’s disease and PARK22016

    • Author(s)
      T. Hatano, A. Okuzumi, K. Kamagata, K. Daida, D. Taniguchi, M. Hori, H. Yoshino, S. Aoki, N. Hattori
    • Organizer
      20th International Congress of Parkinson’s disease and Movement Disorders.
    • Place of Presentation
      ベルリン
    • Year and Date
      2016-06-19
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] PDとPSPにおけるメラニンイメージングを用いた黒質神経細胞脱落の検討2016

    • Author(s)
      谷口 大祐,波田野 琢, 鎌形 康司, 奥住 文美, 堀 正明, 青木 茂樹, 服部 信孝
    • Organizer
      第57回日本神経学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16K09675
  • [Presentation] Hyposmia might be linked to inferior temporal cortical thickness in Parkinson’s disease2015

    • Author(s)
      Hatano T, Kamagata K, Okuzumi A, Hori M, Takeda A, Aoki S.
    • Organizer
      日本神経学会総会
    • Place of Presentation
      新潟県新潟市
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Parkinson's disease-associated mutations of PLA2G6 alters the membrane dynamics、英語 ポスター2015

    • Author(s)
      森 聡生、王子 悠、奥住 文美、波田野 琢、今居 譲、久保 紳一郎、服部 信孝.
    • Organizer
      第56回日本神経学会総会
    • Place of Presentation
      朱鷺メッセ、新潟市
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-15H04842
  • [Presentation] λIdentification of novel biomarkers for Parkinson’s disease by metabolomics technologies.2015

    • Author(s)
      Hatano T, Saiki S, Okuzumi A, Hattori N.
    • Organizer
      International congress of Parkinson’s disease and movement disorders.
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2015-06-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Identification of novel biomarkers for Parkinson’s disease by metabolomics technologies.2015

    • Author(s)
      Okuzumi A, Hatano T, Saiki S, Hattori N.
    • Organizer
      日本神経学会総会
    • Place of Presentation
      新潟県新潟市
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Levodopa-responsive Parkinsonism following bilateral putaminal hemorrhages2013

    • Author(s)
      Hatano , T., Kubo , S.I., Niijima-Ishii , Y., Sugita , H., Hattori , N
    • Organizer
      MDS 17th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Continuous dopaminergic stimulation (CDS)実現による運動症状への対応2013

    • Author(s)
      波田野 琢
    • Organizer
      日本神経治療学会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] DJ-1 associates with synaptic membranes2012

    • Author(s)
      Hatano T
    • Organizer
      The movement disorders society's 16th international congress of Parkinson's disease and movement disorders
    • Place of Presentation
      International Congress Dublin Ireland
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Presentation] 膜輸送の障害はLewy小体形成に関与するか2012

    • Author(s)
      波田野 琢
    • Organizer
      第52階日本神経学会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Presentation] パーキンソン病患者の服薬状況に関するアンケート調査2011

    • Author(s)
      波田野 琢 他
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Presentation] シンポジウム パーキンソン病の病態から臨床 up date; 治療2011

    • Author(s)
      波田野 琢
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Presentation] DJ-1はシナプス小胞に局在する2011

    • Author(s)
      波田野 琢 他
    • Organizer
      第5回 日本パーキンソン病・運動障害疾患学会
    • Place of Presentation
      品川プリンスホテル
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Presentation] DJ-1はシナプス小胞に局在する2011

    • Author(s)
      波田野 琢 他
    • Organizer
      第30回 日本認知症学会
    • Place of Presentation
      タワーホール船堀
    • Data Source
      KAKENHI-PROJECT-23700389
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第52回日本神経学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第52回日本神経学会
    • Place of Presentation
      東京(東京国際フォーラム)
    • Year and Date
      2010-05-20
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第18回カテコールアミン研究会
    • Place of Presentation
      品川プリンホテル
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] 家族性パーキンソン病原因遺伝子PINK1のmitophagy調節機構について2010

    • Author(s)
      河尻澄宏、斉木臣二、佐藤栄人、波田野琢、里史明、江口博人、服部信孝
    • Organizer
      第18回カテコールアミン研究会
    • Place of Presentation
      東京(品川プリンスホテル)
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21790853
  • [Presentation] パーキンソン病患者の服薬状況と治療費用について2009

    • Author(s)
      波田野琢, 他
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] Parkinの放出機構への影響の検討2009

    • Author(s)
      江口博人, 今泉美佳, 近岡洋子, 佐藤栄人, 波田野琢, 他
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] Parkin knockout mouse脳を用いた蛋白質プロファイリング解析2009

    • Author(s)
      今井哲司, 波田野琢, 他
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] Unmet needs of Parkinson's disease patients2008

    • Author(s)
      Taku Hatano
    • Organizer
      The 12^<th> International Congress of Parki nson' s disease and Movement disorders Chicago
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] パーキンソン病のunmet needs2008

    • Author(s)
      波田野琢, 他
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] Proteomic analysis of parkin-deficient mice : the possible alteration in protein content in the midbrain2008

    • Author(s)
      Taku Hatano
    • Organizer
      133^<rd> Annual Meeting
    • Place of Presentation
      Salt Lake City
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] DJ-1蛋白の細胞膜組織における局在に関する検討2008

    • Author(s)
      波田野琢, 他
    • Organizer
      第27回日本認知症学会
    • Place of Presentation
      前橋
    • Data Source
      KAKENHI-PROJECT-20790624
  • [Presentation] 本邦におけるLRRK2-R1441G変異に関連したパーキンソン病の臨床的特徴

    • Author(s)
      波田野 琢, 舩山 学, 久保 紳一郎, Ignacio Mata, 吉野 浩代, 王子 悠, 森 聡生, 藤本 健一, 大島 洋和, 國井 泰人, 矢部 博興, 水野 美邦, 服部 信孝
    • Organizer
      2014年 第55回 日本神経学会総会 福岡 5月21-24日
    • Place of Presentation
      福岡,福岡国際会議場・福岡サンパレス・福岡国際センター
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] GBA変異によるglucocerebrosidaseの局在変化の検討

    • Author(s)
      王子 悠,森 聡生, 波田野 琢, 久保 紳一郎, 服部 信孝
    • Organizer
      2014年 第55回 日本神経学会総会 福岡 5月21-24日
    • Place of Presentation
      福岡,福岡国際会議場・福岡サンパレス・福岡国際センター
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] PLA2G6における細胞内局在の変化および病態の検討

    • Author(s)
      森 聡生, 王子 悠, 奥住 文美, 波田野 琢, 久保 紳一郎, 服部 信孝
    • Organizer
      2014年 第55回 日本神経学会総会 福岡 5月21-24日
    • Place of Presentation
      福岡,福岡国際会議場・福岡サンパレス・福岡国際センター
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Identification of a Japanese family with Parkinson’s disease due to the LRRK2 p.R1441G mutation

    • Author(s)
      T. Hatano, M. Funayama, S.-I. Kubo, I.F. Mata, Y. Oji, A. Mori, C.P. Zabetian, S. Waldherr, H. Yoshino, G. Oyama, Y. Shimo, K.-I. Fujimoto, H. Oshima, Y. Kunii, H. Yabe, Y. Mizuno, N. Hattori
    • Organizer
      18th International congress of Parkinson’s disease and movement disorders.
    • Place of Presentation
      ストックホルム,スウェーデン
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Mutant glucocerebrosidase changes its subcellular localization

    • Author(s)
      Y. Oji, A. Mori, T. Hatano, S-I. Kubo, N. Hattori
    • Organizer
      18th International congress of Parkinson’s disease and movement disorders.
    • Place of Presentation
      ストックホルム,スウェーデン
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-25461290
  • [Presentation] Intracellular localization of PLA2G6

    • Author(s)
      A. Mori, Y. Oji, A. Okuzumi, T. Hatano, S-I. Kubo, N. Hattori.
    • Organizer
      18th International congress of Parkinson’s disease and movement disorders.
    • Place of Presentation
      ストックホルム,スウェーデン
    • Year and Date
      2014-06-08 – 2014-06-12
    • Data Source
      KAKENHI-PROJECT-25461290
  • []

  • 1.  HATTORI Nobutaka (80218510)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 34 results
  • 2.  SATO Shigeto (00445537)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 3.  SAIKI Shinji (00339996)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 4.  FUNAYAMA Manabu (70468578)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  IMOTO Masaya (60213253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Fukunaga Tetsu (20245731)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  上野 真一 (40875944)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 8.  李 賢哲 (30758321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  折田 創 (50465069)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SHIOMO Yashushi (70286714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  EGUCHI Hiroto (20380868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 12.  TANIDA Isei (30296868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MATSUDA Noriyuki (10332272)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOMATSU Masaaki (90356254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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