ishihara hisamitsu 石原寿光

… Alternative Names

ISHIHARA Hisamitsu 石原寿光

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Researcher Number	60361086
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 日本大学, 医学部, 教授 2008 – 2022: Nihon University, 医学部, 教授 2010: 日本大学, 医学部・内科学系, 教授 2008: Nihon University, 医学部, 医学部 2006 – 2007: Tohoku University Hospital, Lecturer, 病院, 講師 … More 2003 – 2006: 東北大学, 病院・助手 2005: 東北大学, 病院, 助手 2004 – 2005: 東北大学, 大学病院, 助手 2003: Tohoku University, Hospital, Research Associate, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Pathological medical chemistry Except Principal Investigator Metabolomics / Metabolomics / Biological Sciences / Pathological medical chemistry
Keywords	Principal Investigator インスリン分泌 / 膵ランゲルハンス島 / 膵島 / インスリン / シグナル伝達 / 糖尿病 / 遺伝子発現修飾 / 膵β細胞 / インスリン分泌機構 / グルカゴン分泌 … More / グルカゴン / 細胞内シグナル伝達 / 細胞内代謝 / グルカゴン分泌機構 / 2型糖尿病 / 偽膵島 / metabolic reprogramming / glucose metabolism / pancreatic alpha-cells / pancreatic beta-cells / 遺伝子改変 / オミックス / TCAサイクル / 解糖系 / トランスクリプトーム / メタボローム / 遺伝子操作 / β細胞 / リコンビナーゼ / recombinase / Signal Transduction / Pancreatic Islet / Diabetes Mellitus / 分子生物学 / カルシウム / マイクロアレイ / アポトーシス / 小胞体ストレス / スルホニル尿素薬 / 膵α細胞 / メトホルミン / DPP-4阻害薬 / スルホニル尿素受容体 / インクレチン / インスリン抵抗性 … More Except Principal Investigator 糖尿病 / インスリン抵抗性 / インスリン分泌 / insulin resistance / Diabetes / 小胞体ストレス / 膵β細胞 / インスリン / diabetes / 2型糖尿病 / インスリン受容体基質1 / インスリン受容体 / シアリダーゼ / ガングリオシド / 転写因子 / ガングリオシド抗体 / 膵ラ島β細胞 / DNA / Chimeric RNA / 一塩基置換修復法 / ミトコンドリアDNA / ミトコンドリア / 膵ラ島 / Gene knockdown / Liver / Insulin / Nitric Oxide / Parasympatic nerve / Urotensin II / 遺伝子ノックダウン / 肝臓 / 一酸化窒素 / 副交感神経 / ウロテンシンII / endoplasmic reticulum stress / pancreatic β cell / insulin secretion / 小胞体カルシウム / WFS1 / oxidative stress / transcription factor / type 2 diabetes / フォークヘッドファミリー / 若年発症糖尿病 / 酸化ストレス / insulin receptor substrate 1 / insulin receptor / glucose tolerance / adenovirus vector / sialidase / ganglioside / 耐糖能 / アデノウイルスベクター / gene therapy / metabolic syndrome / obesity / 遺伝子治療 / メタボリック症候群 / 肥満 / inositol glycan / impairment of insulin secretion / GPI specific phospholipase D / Type 2 diabetes mellitus / イノシトールグリカン / インスリン分泌不全 / GPI特異的フォスフォリパーゼD / Insulin receptor substrate 1 / Insulin receptor / Knockout mice / Transgenic mice / Insulin resistance / Sialidase / Ganglioside / タンスジェニックマウス / ノックアウトマウス / トラスジェニックマウス / cell cycle / Endoplasmic reticulum stress / Wolfram syndrome / pancreatic B cell / Insulin secretion / glutamate / PPARa / GLUD1 / GDH / GPLD1 / ウェルナー症候群 / SNP / 細胞周期 / ウオルフラム症候群 / PYY / VDR / ペプチドホルモン / 組織特異的 / 膵臓 / ビタミンD受容体 / 核内受容体 / 標的遺伝子 / ビタミンD / 膵臓学 / 分子病態学 / 増殖 / 再生治療 / 頚動脈弾性特性 / 電子的染色法 / 動脈硬化症 / 位相差トラッキング法 / グリセロールキナーゼ / ジカルボン酸輸送担体 / グルカゴン Less

Molecular mechanisms underlying metabolism-secretion coupling in endocrine cells of the islets of LangerhansPrincipal Investigator
- Principal Investigator
  
  石原寿光
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nihon University
Metabolic features of hormone secreting cells in pancreatic islets and analyses of their dysfunction using pseudo-isletsPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nihon University
Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysisPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nihon University
Development of an efficient method for generation of genetically modified insulin secreting cells and its application for studies on insulin secretionPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Nihon University
Analysis of glucagon seceretion mechanisms and its modulation by anti-diabetes drugsPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nihon University
Molecular mechanism of regulation of expression and identificati on of novel target gene of vitamin D in the pancreas
- Principal Investigator
  
  CHOI Mihwa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nihon University
Molecular mechanisms of pancreaticβ-cell failure and insulin resistance due to impaired ER stress responsePrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Nihon University
Pancreatic β cell impairment and adaptation of type 2 diabetes mellitus in overnutrition era
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The molecular mechanisms of transcriptional and translational control of stress responses in pancreatic β cellsPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nihon University
  Tohoku University
ミトコンドリア遺伝子異常糖尿病に対する遺伝子治療の開発
- Principal Investigator
  
  檜尾好徳 (桧尾好徳)
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
動脈硬化早期診断法の確立-血管壁の電子的染色法を用いて
- Principal Investigator
  
  岡芳知
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Molecular mechanisms for pancreatic beta cell failure・a viewpoint from endoplasmic reticulum stress
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Molecular Mechanisms for Pancreatic Islet Disfunction in Development of Diabetes Mellitus-a study using WFS1 knockout micePrincipal Investigator
- Principal Investigator
  
  ISHIHARA Hisamitsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Signaling axis of urotensin II, parasympathetic nerves, and nitric oxide on carbohydrate metabolism: A clinical
- Principal Investigator
  
  TAMURA Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
膵ラ島β細胞ミトコンドリアを標的とする遺伝子治療の開発
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Elucidation of abnormality of plasma membrane microdomain in type 2 diabetes mellitus
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The role of genes of forkhead transcription factors in type2 diabetes and obesity.
- Principal Investigator
  
  HINOKIO Yoshinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
転写ターゲティングシステム構築による膵島ホルモン分泌制御機構の解析と遺伝子治療
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Development of gene therapy for diabetes associated with obesity
- Principal Investigator
  
  KATAGIRI Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The role of plasma membrane type sialidase gene Neu3 on the pathogenesis of type 2 diabetes mellitusin Japanese.
- Principal Investigator
  
  SUZUKI Susumu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
The role of phospholipase D in the development of diabetes mellitus
- Principal Investigator
  
  HIRAI Masashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  TOHOKU UNIVERSITY
Elucidation of diabetes-related genes
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University

[Book] WFS1 Protein (wolframin): Emerging Link between the Emotional Brain and Endocrine Pancreas. (Chapter 3. Role of endoplasmic reticulum stress in pancreatic β cell loss in WFS1-deficient mice) (Koks and Vasar ed.)2009
- Author(s)
  Ishihara H, Yamaguchi S, Yamada T, Tamura A, Oka Y
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-19590300
[Book] WFS1 Protein (wolframin): Emerging Link between the Emotional Brain and Endocrine Pancreas. (Chapter 2. Progressive β cell loss and defective) (Koks and Vasar ed.)2009
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, Yamaguchi S, Takei D, Yamada T, Inoue H, Tanizawa Y, Oka Y
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-19590300
[Book] WFS1 Protein(wolframin) : Emerging Link between the Emotional Brain and Endocrine Pancreas2009
- Author(s)
  石原寿光
- Publisher
  WFS1 Protein(wolframin) : Emerging Link between the Enotional Brain and Endocrine pancreas
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes.2023
- Author(s)
  Tomofuji Y, Suzuki K, Kishikawa T, Shojima N, Hosoe J, Inagaki K, Matsubayashi S, Ishihara H, Watada H, Ishigaki Y; BioBank Japan Project; Inohara H, Murakami Y, Matsuda K, Okada Y, Yamauchi T, Kadowaki T
- Journal Title
  
  Communications Medicine
  
  Volume: 3 Issue: 1 Pages: 5-5
- DOI
  10.1038/s43856-022-00231-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918, KAKENHI-PROJECT-20H03525
[Journal Article] A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness,2023
- Author(s)
  Tanaka A, Kosuda M, Yamana M, Furukawa A, Nagasawa A, Fujishiro M, Kohno G, Ishihara H.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 5654-5654
- DOI
  10.1038/s41598-023-32589-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08918, KAKENHI-PROJECT-20K11590
[Journal Article] Fibrosis-4 index is closely associated with arterial damage and future risk of coronary heart disease in type 2 diabetes2022
- Author(s)
  Watanabe K, Takakubo N, Saigusa T, Nagasawa A, Yamana M, Ojima M, Kameda W, Susa S, Ishizawa K, Ishihara H.
- Journal Title
  
  Int J Hypertension
  
  Volume: 2022 Pages: 2760027-2760027
- DOI
  10.1155/2022/2760027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Glucagon Response to Glucose Challenge in Patients with Idiopathic Postprandial Syndrome2022
- Author(s)
  Kosuda M, Watanabe K, Koike M, Morikawa A, Saito H, Kohno G, Ishihara H.
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 89 Issue: 1 Pages: 102-107
- DOI
  10.1272/jnms.JNMS.2022_89-205
- NAID
  130008087911
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2022-02-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Aortic arch calcification with pericardial fat mass detected on a single chest X-ray image is closely associated with the predictive variables of future cardiovascular disease2022
- Author(s)
  Watanabe K, Hada Y, Ishii K, Nagaoka K, Takase K, Kameda W, Susa S, Saigusa T, Egashira F, Ishihara H, Ishizawa K.
- Journal Title
  
  Heart Vessels
  
  Volume: 37 Issue: 4 Pages: 654-664
- DOI
  10.1007/s00380-021-01948-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Metabolism-secretion coupling in glucose-stimulated insulin secretion2022
- Author(s)
  Ishihara H
- Journal Title
  
  Diabetology International
  
  Volume: - Issue: 3 Pages: 463-470
- DOI
  10.1007/s13340-022-00576-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Using recombinase-mediated cassette exchange to engineer MIN6 insulin-secreting cells based on a newly identified safe harbor locus2021
- Author(s)
  Furukawa A, Tanaka A, Yamaguchi S, Kosuda M, Yamana M, Nagasawa A, Kohno G, Ishihara H.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 12 Pages: 2129-2140
- DOI
  10.1111/jdi.13646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Effects of GLP-1RA and SGLT2i, alone or in combination, on mouse models of type 2 diabetes representing different disease stages2021
- Author(s)
  Koike M, Saito H, Kohno G, Takubo M, Watanabe K, Ishihara H.
- Journal Title
  
  International J Molecular Science
  
  Volume: 22 Issue: 21 Pages: 11463-11463
- DOI
  10.3390/ijms222111463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Glucagon responses to glucose challenge in patients with idiopathic postprandial syndrome2021
- Author(s)
  Kosuda M, Watanabe K, Koike M, Morikawa A, Saito H, Kohno G, Ishihara H.
- Journal Title
  
  J Nippon Medical School
  
  Volume: -
- NAID
  130008087911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes2021
- Author(s)
  Fujishiro Midori、Ishihara Hisamitsu、Ogawa Katsuhiko、Murase Takayo、Nakamura Takashi、Watanabe Kentaro、Sakoda Hideyuki、Ono Hiraku、Yamamotoya Takeshi、Nakatsu Yusuke、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 8 Pages: 1052-1052
- DOI
  10.3390/biomedicines9081052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-20K08918, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580
[Journal Article] Seasonal variation in hydration status among community-dwelling elderly in Japan2020
- Author(s)
  Tanaka S, Fujishiro M, Watanabe K, Imatake K, Suzuki Y, Abe M, Ishihara H, Tani S
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 20 Issue: 10 Pages: 904-910
- DOI
  10.1111/ggi.14010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] A rare case of fulminant type 1 diabetes mellitus accompanied by both acute pancreatitis and myocarditis - case report2020
- Author(s)
  Egashira F, Kawashima M, Morikawa A, Kosuda M, Ishihara H, Watanabe K.
- Journal Title
  
  BMC Endocr Disord
  
  Volume: 20 Issue: 1 Pages: 127-127
- DOI
  10.1186/s12902-020-00607-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Comparison of tofogliflozin versus glimepiride as the third oral agent added to metformin plus a dipeptidyl peptidase-4 inhibitor in Japanese patients with type 2 diabetes: A randomized, 24-week, open-label, controlled trial (STOP-OB)2020
- Author(s)
  Kitazawa T, Seino H, Ohashi H, Inazawa T, Inoue M, Ai M, Fujishiro M, Kuroda H, Yamada M, Anai M, Ishihara H.
- Journal Title
  
  Diabetes Obes Metab
  
  Volume: 22 Issue: 9 Pages: 1659-1663
- DOI
  10.1111/dom.14059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Effect of adult weight gain on non-alcoholic fatty liver disease and its association with anthropometric parameters in the lean Japanese population2020
- Author(s)
  Tanaka S, Fujishiro M, Watanabe K, Imatake K, Suzuki Y, Abe M, Ishihara H, Tani S.
- Journal Title
  
  Diagnostics
  
  Volume: 10 Issue: 11 Pages: 863-863
- DOI
  10.3390/diagnostics10110863
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08918
[Journal Article] Two adult siblings with myotonic dystrophy type 1 with different phenotypes presenting with chronic respiratory insufficiency and sleep apnea syndrome2019
- Author(s)
  3.Kohno G, Ogawa K, Kushimoto M, Tanaka S, Ikeda J, Nishizawa T, Mitsuke K, Nakayama T, Suzuki Y, Ishihara H, Fujishiro M.
- Journal Title
  
  Front Neurol
  
  Volume: 10 Pages: 681-681
- DOI
  10.3389/fneur.2019.00681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09850
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-13432-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] Difficulty diagnosing acute pancreatitis possibly masked by severe hypertriglyceridemia in an obese patient with ketoacidosis-onset type 2 diabetes2017
- Author(s)
  Fujishiro M, Horita A, Nakagawara H, Mawatari T, Kishigami Y,Tominaga Y, Moriyama M, Ishihara H.
- Journal Title
  
  Int Med.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15351
[Journal Article] The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion2017
- Author(s)
  Nakatsu Y, Mori K, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mitsuzaki-Miyoshi K, Sakoda H, Fujishiro M, Yamaguchi S, Kushiyama A, Ono H, Ishihara H, Asano T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 28 Pages: 11886-11895
- DOI
  10.1074/jbc.m117.780726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] Diabetes mellitus not an unfavorable factor on the prognosis of hepatitis C virus-related hepatocellular carcinoma.2017
- Author(s)
  Yoshida N, Midorikawa Y, Higaki T, Nakayama H, Tsuji S, Matsuoka S, Ishihara H, Moriyama M, Takayama T.
- Journal Title
  
  Hepatol Res.
  
  Volume: 印刷中 Issue: 1 Pages: 28-35
- DOI
  10.1111/hepr.12888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15351, KAKENHI-PROJECT-15K10152
[Journal Article] Efficacy and safety of ipragliflozin as add-on therapy to insulin in Japanese patients with type 2 diabetes mellitus (IOLITE): a multi-centre, randomized, placebo-controlled, double-blind study.2016
- Author(s)
  Ishihara H, Yamaguchi S, Nakao I, Okitsu A, Asahina S.
- Journal Title
  
  Diabetes Obes Metab.
  
  Volume: 18 Issue: 12 Pages: 1207-1216
- DOI
  10.1111/dom.12745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15351
[Journal Article] Is zinc an intraislet regulator of glucagon secretion?2016
- Author(s)
  Ishihara H, Wollheim CB.
- Journal Title
  
  Diabet Int.
  
  Volume: 7 Issue: 2 Pages: 106-110
- DOI
  10.1007/s13340-016-0259-x
- NAID
  40020883101
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15351
[Journal Article] Addition of sitagliptin or metformin to insulin monotherapy improves blood glucose control <i>via</i> different effects on insulin and glucagon secretion in hyperglycemic Japanese patients with type 2 diabetes2015
- Author(s)
  Otsuka Y, Yamaguchi S, Furukawa A, Kosuda M, Nakazaki M, Ishihara H.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 2 Pages: 133-143
- DOI
  10.1507/endocrj.EJ14-0148
- NAID
  130004699224
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591343
[Journal Article] Octreotide for hypoglycemia caused by sulfonylurea and DPP-4 inhibitor.2015
- Author(s)
  Yamaguchi, S., Ikejima, M., Furukawa, A., Abe, M., Nakazaki, M., Ishihara, H.
- Journal Title
  
  Diabetes Res Clin Pract.
  
  Volume: 109 Issue: 2 Pages: e8-e10
- DOI
  10.1016/j.diabres.2015.05.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15351
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice2015
- Author(s)
  Ｓhinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Nishimura F, Asano T.
- Journal Title
  
  Diabetol Metab Syndr
  
  Volume: ７ Issue: 1 Pages: 50-50
- DOI
  10.1186/s13098-015-0047-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15351, KAKENHI-PROJECT-25461372
[Journal Article] Inhibition ameliorates pancreatic β-cell failure and improves glucose tolerance in the mouse model of Wolfram syndrome2015
- Author(s)
  Tanji Y, Yamaguchi S, Ishigaki Y, Katagiri H, Oka Y, Ishihara H.
- Journal Title
  
  J Diabet Mellitus
  
  Volume: 5 Issue: 02 Pages: 72-80
- DOI
  10.4236/jdm.2015.52009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15351
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 309(3) Issue: 3 Pages: E214-E223
- DOI
  10.1152/ajpendo.00553.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15K15351, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] The cutting-edge of medicine: glucagon renaissance2013
- Author(s)
  Ishihara H
- Journal Title
  
  Nihon Naika Gakkai Zasshi
  
  Volume: 102 Pages: 3237-3243
- NAID
  40019918166
- Data Source
  KAKENHI-PROJECT-24591343
[Journal Article] Vitamin D receptor activation induces peptide YY transcription in pancreatic islets.2012
- Author(s)
  Choi M, Ozeki J, Hashizume M, Kato S, Ishihara H, Makishima M
- Journal Title
  
  Endocrinology
  
  Volume: 153 (11) Issue: 11 Pages: 5188-5199
- DOI
  10.1210/en.2012-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590295
[Journal Article] Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance2012
- Author(s)
  M.Usui, S.Yamaguchi, Y.Tanji, R.Tominaga, Y.Ishigaki, M.Fukumoto, H.Katagiri, K.Mori, Y.Oka, H.Ishihara
- Journal Title
  
  Metabol
  
  Volume: (in press) Issue: 8 Pages: 1118-28
- DOI
  10.1016/j.metabol.2012.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058009, KAKENHI-PROJECT-21591147, KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-24591343, KAKENHI-PROJECT-24659174, KAKENHI-PROJECT-24659439
[Journal Article] Vitamin D Receptor Activation Induces Peptide YY Transcription in Pancreatic Islets2012
- Author(s)
  Choi Mihwa, Ozeki Jun, Hashizume Masami, Kato Shigeaki, Ishihara Hisamitsu, Makishima Makoto
- Journal Title
  
  Endocrinology
  
  Volume: Vol.153、No.11 Pages: 5188-5199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590295
[Journal Article] Hepatic nuclear factor 1alpha(HNF1alpha) dysfunction down-regulates X-box-binding protein 1(XBP1) and sensitizes beta-cells to endoplasmic reticulum stress2011
- Author(s)
  Kirkpatrick CL, Wiederkehr A, BaquieM, Akhmedov D, Wang H, Gauthier BR, Akerman I, Ishihara H, Ferrer J, Wollheim CB
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 37 Pages: 323000-32312
- DOI
  10.1074/jbc.m111.247866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591147
[Journal Article] The JNK pathway modulates expression and phosphorylation of the translational suppressor 4E-BP1 in MIN6 pancreatic beta-cells under oxidative stress conditions2010
- Author(s)
  Tominaga R, Yamaguchi S, Satake C, Usui M, Tanji Y, Kondo K, Katagiri H, Oka Y, Ishihara H
- Journal Title
  
  Cell Biochem Funct
  
  Volume: 28 Issue: 5 Pages: 387-393
- DOI
  10.1002/cbf.1667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591147, KAKENHI-PROJECT-22790842
[Journal Article] Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells2010
- Author(s)
  Fonseca SG, Ishigaki S, Oslowski CM, Lu S, Lipson KL, Ghosh R, Hayashi E, Ishihara H, Oka Y, Permutt MA, Urano F
- Journal Title
  
  J Clin Invest
  
  Volume: 120 Issue: 3 Pages: 744-755
- DOI
  10.1172/jci39678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591147
[Journal Article] Carotid arterial elasticity is a sensitive atherosclerosis value reflecting visceral fat accumulation in obese subjects.2009
- Author(s)
  Tokita A, Ishigaki Y, Okimoto H, Hasegawa H, Koiwa Y, Kato M, Ishihara H, Hinokio Y, Katagiri H, Kanai H, Oka Y.
- Journal Title
  
  Atherosclerosis 206
  
  Pages: 168-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Carotid arterial elasticity is a sensitive atherosclerosis value reflecting visceral fat accumulation in obese subjects2009
- Author(s)
  Tokita A, Ishigaki Y, Okimoto H, Hasegawa H, Koiwa Y, Kato M, Ishihara H, Hinokio Y, Katagiri H, Kanai H, Oka Y
- Journal Title
  
  Atherosclerosis
  
  Volume: 206 Pages: 168-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591147
[Journal Article] Carotid arterial elasticity is a sensitive atherosclerosis value reflecting visceral fat accumulation in obese subjects2009
- Author(s)
  Tokita A, Ishigaki Y, Okimoto H, Hasegawa H, Koiwa Y, Kato M, Ishihara H, Hinokio Y, Katagiri H, Kanai H, Oka Y.
- Journal Title
  
  Atherosclerosis 206
  
  Pages: 168-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress2008
- Author(s)
  Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tashiro F, Aburatani H, Tsukiyama-Kohara K, Miyazaki J, Sonenberg N, Oka Y
- Journal Title
  
  Cell Metab 7
  
  Pages: 269-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Regulation of pancreatic β cell mass by neuronal signals from the liver2008
- Author(s)
  Imai J, Katagiri H, Yamada T, Ishigaki Y, Suzuki T, Kudo H, Uno K, Hasegawa Y, Gao J, Kaneko K, Ishihara H, Niijima A, Nakazato M, Asano T, Minokoshi Y, Oka Y.
- Journal Title
  
  Science 322
  
  Pages: 1250-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress2008
- Author(s)
  山口賢, 石原寿光, 山田高広, 田村明, 薄井正寛, 富永竜, 宗像佑一郎, 佐竹千尋, 片桐秀樹, 田代文, 油谷浩幸, 小原恭子, 宮崎純一, Nahum Sonenberg, 岡芳知
- Journal Title
  
  Cell Metabolism 7
  
  Pages: 269-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress2008
- Author(s)
  Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tashiro F, Aburatani H, Tsukiyama-Kohara K, Miyazaki J, Sonenberg N, Oka Y.
- Journal Title
  
  Cell Metabolism 7
  
  Pages: 269-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Behavioral and gene expression analyses of WFS1 knockout mice as apossible animal model of mood disorder2008
- Author(s)
  Kato T, Ishiwata M, Yamada K, Kasahara T, Kakiuchi C, Iwamoto K, Kawamura K, Ishihara H, Oka Y.
- Journal Title
  
  Neuroscience Research 61
  
  Pages: 143-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] The GDP-dependent Rab27aeffector coronin 3 controls endocytosis of seceratry membrane in insulin secreting cell lines2008
- Author(s)
  Kimura T, Kaneko Y, Yamada S, Ishihara H, Senda T, Iwamatsu A, Niki I
- Journal Title
  
  J Cell Sci 121
  
  Pages: 3092-3098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survivalunder endoplasmic reticulum stress2008
- Author(s)
  Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tasbiro F, Aburatani H, Tsukiyama-Kohara K, Miyazaki J, Sonenberg N, Oka Y.
- Journal Title
  
  Cell Metabolism 7
  
  Pages: 269-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Regulation of pancreatic β cell mass by neuronal signals from the liver2008
- Author(s)
  Imai J, Katagiri H, Yamada T, Ishigaki Y, Suzuki T, Kudo H, Uno K, Hasegawa Y, Gao J, Kaneko K, Ishihara H, Niijima A, Nakazato M, Asano T Minokoshi Y, Oka Y.
- Journal Title
  
  Science 322
  
  Pages: 1250-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder2008
- Author(s)
  Kato T, Ishiwata M, Yamada K, Kasahara T, Kakiuchi C, Iwamoto K, Kawamura K, Ishihara H, Oka Y
- Journal Title
  
  Neurosci Res 61
  
  Pages: 143-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis2008
- Author(s)
  Ishigaki Y, Katagiri H, Gao J, Yamada T, Imai J, Uno K, Hasegawa Y, Kaneko K, Ogihara T, Ishihara H, Sato Y, Takikawa K, Nishimichi N, Matsuda H, Sawamura T, Oka Y.
- Journal Title
  
  Circulation 118
  
  Pages: 75-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder2008
- Author(s)
  加藤忠文, 石渡みずほ, 山田一之, 笠原和起, 垣内千尋, 岩本和也, 河村光毅, 石原寿光, 岡芳知
- Journal Title
  
  Neuroscience Research (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis2008
- Author(s)
  Ishigaki Y, Katagiri H, Gao J, Yamada T, Imai J, Hasegawa Y, Kaneko K, Ogihara T, Ishihara H, Sata Y, Takikawa K, Nishimichi N, Matsuda, H., Sawamura, T., Oka, Y
- Journal Title
  
  Circulation 118
  
  Pages: 75-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Minokoshi Y, Oka Y. Regulation of Pancreatic β cell Mass by Neuronal Signals from the Liver2008
- Author(s)
  Imai J, Katagiri H, Yamada T, Ishigaki Y, Suzuki T, Kudo H, Uno K, Hasegawa Y, Gao J, Kaneko K, Ishihara H, Niijima A, Nakazato M, Asano T
- Journal Title
  
  Science 322
  
  Pages: 1250-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Bone marrow (BM) transplantation promotes β-cell regeneration after acute injury through BM cell mobilization2007
- Author(s)
  Hasegawa Y, Ogihara T, Yamada T, Ishigaki Y, Imai J, Uno K, Gao J, Kaneko K, Ishihara H, Sasano H, Nakauchi H, Oka Y, Katagiri H
- Journal Title
  
  Endocrinology 148
  
  Pages: 2006-2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S, Yamada T, Katagiri H, Oka Y.
- Journal Title
  
  J Mol Endocrinol 38・1-2
  
  Pages: 127-136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S, Yamada T, Katagiri H, Oka Y
- Journal Title
  
  J Mol Endocrinol 38・1-2
  
  Pages: 127-136
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  J Mol Endocrinol. 38・1
  
  Pages: 127-136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Bone marrow(BM)transplantation promotes β cell regeneration after acute injury through BM cell mobilization2007
- Author(s)
  長谷川豊, 荻原健英, 山田哲也, 石垣泰, 今井淳太, 宇野健司, 高俊文, 金子慶三, 石原寿光, 笹野公伸, 中内拓光, 岡芳知, 片桐秀樹
- Journal Title
  
  Endocrinology 148
  
  Pages: 2006-2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] The conserved carboxyl terminus of human parainfluenza virus type 2 V protein plays an important role in virus growth2007
- Author(s)
  Nishio M, Tsurudome M, Ishihara H, Ito M, Ito Y
- Journal Title
  
  Virology 362
  
  Pages: 85-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Journal Article] Bone marrow (BM) transplantation promotes {beta} cell regeneration after acute injury through BM cell mobilization2007
- Author(s)
  Hasegawa Y, Ogihara T, Yamada T, Ishigaki Y, Imai J, Uno K, Gao J, Kaneko K, Ishihara H, Sasano H, Nakauchi H, Oka Y, Katagiri H.
- Journal Title
  
  Endocrinology 148
  
  Pages: 2006-2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S. Yamada T, Katagiri H, Oka Y.
- Journal Title
  
  J Mol Endocrinol 38
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  J Mol Endocrinol 38・1
  
  Pages: 127-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S, Yamada T, Katagiri H, Oka Y.
- Journal Title
  
  J Mol Endocrinol 38
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209034
[Journal Article] WFS 1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.2006
- Author(s)
  Yamada T, Ishihara H, et al.
- Journal Title
  
  Hum Mol Genet. 15・10
  
  Pages: 1600-1609
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic β-cells.2006
- Author(s)
  Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J-I, Oka Y
- Journal Title
  
  Hum Mol Genet 15・10
  
  Pages: 1600-1609
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFSI protein modulates the free Ca(2+) concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, et al.
- Journal Title
  
  FEBS Lett. 580・24
  
  Pages: 5635-5640
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes and liver cirrhosis.2006
- Author(s)
  Tamura A, Ishihara H, et al.
- Journal Title
  
  Nippon Naika Gakkai Zasshi 95.7
  
  Pages: 1371-1374
- NAID
  10018198589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, et al.
- Journal Title
  
  FEBS Lett 580・24
  
  Pages: 5635-5640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, Tamura A, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] Cell-type specific activation of metabolism reveals that β-cell secretion suppresses glucagon release from α-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, Tamura A, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab. 290
  
  Pages: 308-316
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13204062
[Journal Article] WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.2006
- Author(s)
  Yamada T, Ishihara H, et al.
- Journal Title
  
  Hum Mol Genet. 15・10
  
  Pages: 1600-1609
- Data Source
  KAKENHI-PROJECT-18659263
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, Tamura A, Yamaguchi S, Yamada T, Takei D, Katagiri H, Endou H, Oka Y.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.2006
- Author(s)
  Yamada T, Ishihara H, et al.
- Journal Title
  
  Hum Mol Genet 15・10
  
  Pages: 1600-1609
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Hypoglycemia associated with hyperinsulinemia in a subject with type 2 diabetes and liver cirrhosis.2006
- Author(s)
  Tamura A, Ishihara H, et al.
- Journal Title
  
  Nippon Naika Gakkai Zasshi 95・7
  
  Pages: 1371-1374
- NAID
  10018198589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y
- Journal Title
  
  FEBS Lett 580.24
  
  Pages: 5635-5640
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, et al.
- Journal Title
  
  FEBS Lett. 580・24
  
  Pages: 5635-5640
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WFS1 protein modulates the free Ca(2+)concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, et al.
- Journal Title
  
  FEBS Lett. 580・24
  
  Pages: 5635-5640
- Data Source
  KAKENHI-PROJECT-18659263
[Journal Article] WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic 13-cells.2006
- Author(s)
  Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J-I, Oka Y.
- Journal Title
  
  Hum Mol Genet 15・10
  
  Pages: 1600-1609
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, Ct al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y
- Journal Title
  
  FEBS Lett 580・24
  
  Pages: 5635-5640
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-18659263
[Journal Article] WFS1 protein modulates the free Ca2+ concentration in the endoplasmic reticulum.2006
- Author(s)
  Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y.
- Journal Title
  
  FEBS Lett 580・24
  
  Pages: 5635-5640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.2006
- Author(s)
  Yamada T, Ishihara H, et al.
- Journal Title
  
  Hum Mol Genet. 15・10
  
  Pages: 1600-1609
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.2005
- Author(s)
  Ishigaki Y, Katagiri H, Yamada T, Ogihara T, Imai J, Uno K, Hasegawa Y, Gao Junhong, Ishihara H, Shimosegawa T, Sakoda H, Asano T, Oka Y.
- Journal Title
  
  Diabetes 54
  
  Pages: 322-332
- Data Source
  KAKENHI-PROJECT-15659213
[Journal Article] Constitutively active PDX1 induced efficient insulin production in adult murine liver.2005
- Author(s)
  Imai J, Katagiri H, Yamada T, Ishigaki Y, Ogihara T, Uno K, Hasegawa Y, Ishihara H, Sasano H, Mizuguchi H, Asano T, Oka Y.
- Journal Title
  
  Biochem Biophys Res Commun 326・2
  
  Pages: 402-409
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.2005
- Author(s)
  Ishigaki Y, Ishihara H, et al.
- Journal Title
  
  Diabetes 54・2
  
  Pages: 322-332
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.2005
- Author(s)
  Ishigaki Y, Ishihara H, et al.
- Journal Title
  
  Diabetes 54・2
  
  Pages: 322-332
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.2005
- Author(s)
  Satoh J, Takahashi K, Takizawa Y, Ishihara H, Hirai M, Katagiri H, Hinokio Y, Suzuki S, Tsuji I, Oka Y.
- Journal Title
  
  Diabetes Res Clin Pract 70
  
  Pages: 291-297
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.2005
- Author(s)
  Satoh J, Takahashi K, Takizawa Y, Ishihara H, Hirai M, Katagiri H, Hinokio Y, Suzuki S, Tsuji I, Oka Y.
- Journal Title
  
  Diabetes Res Clin Pract. 70
  
  Pages: 291-297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590862
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2005
- Author(s)
  Ishihara H, Takeda S, et al.
- Journal Title
  
  Hum Mol Genet. 13・11
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2005
- Author(s)
  Ishihara H, Takeda S, et al.
- Journal Title
  
  Hum Mol Genet. 13・11
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.2005
- Author(s)
  Ishigaki Y, Katagiri H, Yamada T, Ogihara T, Imai J, Uno K, Hasegawa Y, Gao Junhong, Ishihara H, Shimosegawa T, Sakoda H, Asano T, Oka Y.
- Journal Title
  
  Diabetes 54・2
  
  Pages: 322-332
- Data Source
  KAKENHI-PROJECT-17390258
[Journal Article] Endoplasmic reticulum stress and N-glycosylation. modulate expression of WFS1 protein.2004
- Author(s)
  Yamaguchi S, Ishihara H, Tamura A, Yamada T, Takahashi R, Takei D, Katagiri H, Oka Y
- Journal Title
  
  Biochem Biophys Res Commun 325
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-13204062
[Journal Article] Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein.2004
- Author(s)
  Yamaguchi S, Ishihara H, Tamura A, Yamada T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 3325
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, Yamaguchi S, Takei D, Yamada T, Inoue H, Soga H, Katagiri H, Tanizawa Y, Oka Y.
- Journal Title
  
  Hum Mol Genet 13
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-15659213
[Journal Article] Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.2004
- Author(s)
  Ishigaki Y, Katagiri H, Yamada T, Ishihara H, et al.
- Journal Title
  
  Diabetes 54
  
  Pages: 322-332
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Disruption of the WFS1 gene in mice causes progressive β-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara, H., Takeda, S., Katagiri, H.et al.
- Journal Title
  
  Hum.Mol.Genet. 13
  
  Pages: 1159-1170
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390282
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, et al.
- Journal Title
  
  Hum Mol Genet 13
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-16659236
[Journal Article] Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein.2004
- Author(s)
  Yamaguchi S, Ishihara H, Tamura A, Yamada T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 325
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, et al.
- Journal Title
  
  Hum Mol Genet 13
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-16390259
[Journal Article] Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein2004
- Author(s)
  Yamaguchi S, Ishihara H, Tamura A, Yamada T, Takahashi R, Takei D, Katagiri H, Oka Y.
- Journal Title
  
  Biochem Biophys Res Commun 325
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-15659213
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, Yamaguchi S, Takei D, Yamada T, Inoue H, Soga H, Katagiri H, Tanizawa Y, Oka Y.
- Journal Title
  
  Hum Mol Genet. 13
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-13204062
[Journal Article] Carotid arterial elasticity is a sensitive atherosclerosis value reflecting visceral fat accumulation in obese subjects
- Author(s)
  Tokita A, Ishigaki Y, Okimoto H, Hasegawa H, Koiwa Y, Kato M, Ishihara H, Hinokio Y, Katagiri H, Kanai H, Oka Y
- Journal Title
  
  Atherosclerosis (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590300
[Patent] 動物細胞の染色体上への外来遺伝子の挿入方法2020
- Inventor(s)
  石原　寿光
- Industrial Property Rights Holder
  石原　寿光
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] 膵a細胞株aTC1およびb細胞株MIN6からなる偽膵島の形態とインスリン分泌応答2022
- Author(s)
  盛川愛　斉藤一樹　河野玄太　田久保正洋　小須田南　石原寿光
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] 時計遺伝子chrono (Ciart) 欠損マウスにおける糖代謝の解析2022
- Author(s)
  斉藤一樹　山口賢　田久保正洋　内匠透　河野玄太　石原寿光
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] グルコース応答性インスリン分泌におけるTCA回路酵素の役割の検討2022
- Author(s)
  河野玄太　山名碧　小須田南　石原寿光
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] グルカゴン分泌制御機構研究の新展開：膵島の統合的理解を目指して2022
- Author(s)
  石原　寿光
- Organizer
  第59回日本糖尿病学会関東甲信越地方会（WEB開催）
- Invited
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] 効率的に遺伝子発現修飾が可能なMIN6細胞の作製と応用2021
- Author(s)
  石原　寿光
- Organizer
  第64回日本糖尿病学会年次学術総会（WEB開催）
- Invited
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] Postprandial syndrome におけるグルカゴン分泌の解析2021
- Author(s)
  小須田　南、渡邉　健太郎、小池　将夫、盛川　愛、斎藤　一樹、河野　玄太、石原　寿光
- Organizer
  第64回日本糖尿病学会年次学術総会（WEB開催）
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] 2型糖尿病モデルマウスを用いたGLP-1受容体作動薬およびSGLT2阻害薬の薬効メカニズムの解析2021
- Author(s)
  小池　将夫、斎藤　一樹、田久保　正洋、渡邉　健太郎、石原　寿光
- Organizer
  第64回日本糖尿病学会年次学術総会（WEB開催）
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] 2型糖尿病の経過中に多脾症合併膵体尾部低形成症が判明した1例2021
- Author(s)
  田久保正洋，小須田南，長澤瑛子，山名碧，江頭富士子，渡邉健太郎，今津博雄，石原寿光
- Organizer
  第58回日本糖尿病学会関東甲信越地方会（WEB開催）
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] ビルビン酸輸送担体欠損インスリン分泌細胞株の樹立と解析2020
- Author(s)
  西岡秀典、山名　碧、長澤　瑛子、小須田南、石原寿光
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] ミトコンドリアピルビン酸輸送担体欠損インスリン分泌細胞株の樹立と解析2020
- Author(s)
  西岡秀典，山名碧，長澤瑛子，小須田南，渡邉健太郎，石原寿光
- Organizer
  第63回日本糖尿病学会年次学術集会（WEB開催）
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] Roles of glycolysis distinct from mitochondrial metabolism for signal generation in Insulin secreting cells2020
- Author(s)
  Ishihara H, Nishioka H, Yamana M, Nagasawa A, Kosuda M, Koike M, Kohno G, Saito H
- Organizer
  American Diabetes Association 80th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08918
[Presentation] Roles of ｇlycolysis distinct from mitochondrial metabolism for signal generation in insulin secreting cells2020
- Author(s)
  Ishihara H, Nishioka H, Yamana M, Nagasawa A, Koike M, Saito H, Morikawa A, Kosuda M
- Organizer
  The 80th Scientific Sessions of American Diabetes Assosication
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] 異なる耐糖能障害の形成を呈した筋緊張性ジストロフィー1型の兄妹例2019
- Author(s)
  河野玄太、藤城緑、久志本優、池田迅、田中翔、岡本真由美、江頭富士子、小川克彦、鈴木裕、中山智祥、石原寿光
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] 膵β細胞におけるChrono遺伝子の機能解析2019
- Author(s)
  山口賢、長澤瑛子、山名碧、小須田南、石原寿光
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] Overexpression screening identifies mitochondrial carbonic anhydrase 5b as an important regulator of glucose-stimulated insulin secretion in beta-cells2019
- Author(s)
  Kosuda M, Yamaguchi S, Nakasawa A, Yamana M, Koike M, NIshioka H, Ishihara H.
- Organizer
  American Diabetes Association 79th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] MIN6細胞における解糖系中間体によるインスリン産生制御2019
- Author(s)
  山名碧、藤城緑、藤城緑、山口賢、江頭富士子、藤城緑、渡邉健太郎、石原寿光
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] インスリン分泌におけるCITED4の機能解析2018
- Author(s)
  山口賢、田中彩、小須田南、山名碧、長澤瑛子、石原寿光
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] ブドウ糖応答性の異なるMIN6細胞サブクローンのトランスクリプトーム解析によるインスリン分泌に重要な遺伝子の探索2018
- Author(s)
  田中彩、古川麻美、小須田南、山名碧、山口賢、石原寿光
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K09850
[Presentation] Establishment of efficient gene transfer system based on RMCE method in MIN6 cells and new findings of novel genes involved in insulin secretion.2016
- Author(s)
  Yamaguchi S, Ishihara H.
- Organizer
  第59回日本糖尿病学会年次集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K15351
[Presentation] Establishment of efficient gene transfer system based on RMCE method in MIN6 cells, and new findings of novel genes involved in insulin secretion2016
- Author(s)
  Yamaguchi S, Ishihara H
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都国際会議場ロームシアターみやこめっせ（京都府・京都市）
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K15351
[Presentation] Screening by RMCE-mediated generation of MIN6 cell transformants identifies novel genes important for insulin secretion2015
- Author(s)
  Furukawa A, Tanaka A, Kosuda M, Otsuka Y, Yamaguchi S, Ishihara H.
- Organizer
  Keystone Symposia　　Diabetes： New insights into molecular mechanisms and therapeutic strategies.
- Place of Presentation
  ウェスティン都ホテル京都（京都府・京都市）
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15351
[Presentation] Screening by RMCE-mediated generation of MIN6 cell transformants identifies novel genes important for insulin secretion2015
- Author(s)
  Ishihara H, Yamaguchi S
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関他　（山口県・下関市）
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K15351
[Presentation] 2型糖尿病患者における血漿グルカゴン値の新規ELISA法と従来型RIA法を用いた測定の比較検討2014
- Author(s)
  山口賢，小須田南，田中彩，古川麻美，大塚雄一郎，中崎満浩，石原寿光
- Organizer
  第15回日本内分泌学会関東甲信越支部学術集会
- Place of Presentation
  ラフレさいたま（埼玉県・さいたま市）
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] Modulation of glucagon and insulin secretion by DPP-4 and DPP-4 inhibitors2014
- Author(s)
  Yamaguchi S, Otsuka Y, Ishihara H
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] グルコース応答性インスリノーマの一例2013
- Author(s)
  古川麻美，山口賢，江頭富士子，大塚雄一郎，大川原奈々，東海林忍，岡本真由美，中崎満浩，石原寿光
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] DPP-4阻害薬とGLP-1受容体作動薬2013
- Author(s)
  石原寿光
- Organizer
  第47回糖尿病学の進歩
- Place of Presentation
  四日市市
- Invited
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] グルコース反応性インスリンノーマの一例2013
- Author(s)
  古川麻美，大川原奈々，上野のぶ子，大塚雄一郎，東海林忍，山口賢，江頭富士子，岡本真由美，中崎満浩，武市奈緒美，杉原仁，内田英二，及川眞一，石原寿光
- Organizer
  第56回日本糖尿病学会総会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] Zinc regulates insulin secretion through interaction with histidine residues of SUR1.2013
- Author(s)
  Ishihara H，Otsuka Y，Yamaguchi S，Hurukawa A，Nakazaki M.
- Organizer
  The 73nd Scientific sessions of American Diabetes Association.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] Sitagliptin improves blood glucose control by suppressing glucagon secretion in insulin-treated type 2 diabetic patients2013
- Author(s)
  Otsuka Y，Kosuda M，Ueno N，Yamaguchi S，Nakazaki M，Ishihara H
- Organizer
  The 49th European Association for Study of Diabetes Annual Meeting.
- Place of Presentation
  Balcerona, Spain
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] Identification of PYY as vitamin D target gene in the pancreas2012
- Author(s)
  Choi Mihwa, Ozeki Jun, Kato Shigeaki, Ishihara Hisamitsu, Makishima Makoto
- Organizer
  Keystone Symposia: NuclearReceptors Matrix: Reloaded
- Place of Presentation
  British Columbia
- Data Source
  KAKENHI-PROJECT-22590295
[Presentation] Regulation of islet hormone secretion by intracellular and intercellular mechanisms2012
- Author(s)
  Ishihara H, Yamaguchi S, Otsuka Y, Furukawa A, Nakazaki M
- Organizer
  The 9th Iinternational Diabete Fedeation Western Pacific Region Congress
- Place of Presentation
  京都市
- Invited
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] 糖尿病とがん2011
- Author(s)
  石原寿光
- Organizer
  第50回日本消化器がん検診学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Therapeutic strategy for type 2 diabetes mellitus based on physiology of islet hormone secretion2011
- Author(s)
  石原寿光
- Organizer
  The 16^<th> Japan-Korea symposium on diabetes mellitus
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] インスリン・グルカゴン分泌機構からみた2型糖尿病治療2011
- Author(s)
  石原寿光
- Organizer
  糖尿病学の進歩
- Place of Presentation
  福岡市
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Zcchc12/Sizn1 is a novel ER stress-responsive gene expressed in the pancreatic beta cell2011
- Author(s)
  石原寿光
- Organizer
  The 47^<th> European Association for study of diabetes annual meeting
- Place of Presentation
  Lisbon
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] 糖尿病とがん2011
- Author(s)
  石原寿光
- Organizer
  第50回日本消化器がん検診学会総会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Therapeutic strategy fortype 2 diabetes mellitus based on physiology of islet hormone secretion2011
- Author(s)
  Ishihara H
- Organizer
  The 16^<th> Japan-Korea symposium on diabetes mellitus
- Place of Presentation
  浦安市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] インスリン治療のup to date2011
- Author(s)
  石原寿光
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市(招待講演)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] インスリン治療のup to date2011
- Author(s)
  石原寿光
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Transcriptional and tran slational control in adaptive stress responses in pancreatic beta cells2011
- Author(s)
  Ishihara H
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Zcchc12/Sizn1 is a novel ER stress-responsive gene expressed in the pancreatic beta cell2011
- Author(s)
  Ishihara H
- Organizer
  The 47^<th> European association for study of diabetes annual meeting
- Place of Presentation
  Lisbon, Spain
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] インスリン・グルカゴン分泌機構からみた2型糖尿病治療2011
- Author(s)
  石原寿光
- Organizer
  第45回糖尿病学の進歩
- Place of Presentation
  福岡市
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Translational and transcriptional regulation of stress responses in glucose homeostasis2010
- Author(s)
  Ishihara H
- Organizer
  第33回日本分子生物学会総会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Transcriptional and Translational regulation in Adaptive Responses to Environmental stress in Pancreatic β Cells2010
- Author(s)
  石原寿光
- Organizer
  The Official Satellite Symposium of the 14th International Congress of Endocrinology "New Insight into Pathogenesis and Treatment of Diabetes"
- Place of Presentation
  東京
- Year and Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Transcriptional and translational control in adaptive stress responses in pancreatic β cells2010
- Author(s)
  石原寿光
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Transcriptional and tran slational regulation in adaptive res ponses to environmental stress in pancreatic beta cells2010
- Author(s)
  Ishihara H
- Organizer
  The official satellite symposium of the 14th international congress of endocrinology "New insight into pathogenesis and treatment of diabetes"
- Place of Presentation
  東京
- Year and Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] 2型糖尿病の病態形成におけるインスリン分泌機構の障害2010
- Author(s)
  石原寿光
- Organizer
  第44回糖尿病学の進歩
- Place of Presentation
  大阪市
- Year and Date
  2010-03-06
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Cell type-specific trans criptional regulation of 4E-BP1 under ER stress in MIN6 beta-cells2010
- Author(s)
  Ishihara H
- Organizer
  The 46^<th> European association for study of diabetes annual meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Translational and Transcriptional Regulation of Stress Responses in Glucose Homeostasis2010
- Author(s)
  石原寿光
- Organizer
  日本分子生物学会総会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Cell type-specific transcriptional regulation of 4E-BP1 under ER stress in MIN6 beta cells2010
- Author(s)
  石原寿光
- Organizer
  European Association for Study of Diabetes
- Place of Presentation
  Stockholm
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] 膵β細胞量調節とストレス応答2009
- Author(s)
  石原寿光
- Organizer
  第43回糖尿病学の進歩
- Place of Presentation
  松本市
- Year and Date
  2009-02-20
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞におけるATF6α欠損マウスを用いた検討2009
- Author(s)
  薄井正寛, 石原寿光, 鈴木千登世, 近藤敬一, 丹治泰裕, 冨永竜, 佐竹千尋, 山口賢, 石垣泰, 檜尾好徳, 片桐秀樹, 森和俊, 岡芳知
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] Lilly賞受賞講演: 2型糖尿病発症における膵β細胞障害の分子機構2009
- Author(s)
  石原寿光
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] 加齢・老化と膵β細胞ストレス応答2009
- Author(s)
  石原寿光
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21591147
[Presentation] Role of CHOP in oxidative stress and vascular inflammation.2009
- Author(s)
  Junhong Gao, Hideki Katagiri, Yasushi Ishigaki, Tetsuya Yamada, Shojiro Sawada, Hisamitsu Ishihara, Junta Imai, Kenji Uno, Yutaka Hasegawa, Suguru Yamaguchi, Yoshinori Hinokio, Masataka Mori, Yoshitomo Oka
- Organizer
  第41回日本動脈硬化学会総会
- Place of Presentation
  下関
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] 膵β細胞量の調節におけるmRNA翻訳制御の役割2008
- Author(s)
  石原寿光, 山口賢, 岡芳知
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] 膵β細胞小胞体ストレス応答における翻訳抑制因子4E-BP1の役割2008
- Author(s)
  石原寿光
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森市
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞小胞体ストレス応答における翻訳抑制因子4E-BP1の役割2008
- Author(s)
  石原寿光、山田高弘、山口賢、冨永竜、宗像佑一郎、檜尾好徳、荻原健英、鈴木進、片桐秀樹、岡芳知
- Organizer
  第81回日本内分泌学会学術集会
- Place of Presentation
  青森市
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞量の調節におけるmRNA 翻訳制御の役割2008
- Author(s)
  石原寿光、山口賢、薄井正寛、冨永竜、岡芳知
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞における小胞体ストレス応答と酸化ストレス応答の特徴2008
- Author(s)
  冨永竜, 石原寿光, 岡芳知, 他6名
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] 膵β細胞における小胞体ストレス応答と酸化ストレス応答の特徴2008
- Author(s)
  富永竜、石原寿光、山田高弘、山口賢、宗像佑一郎、檜尾好徳、荻原健英、鈴木進、片桐秀樹、岡芳知
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 翻訳抑制因子4E-BP1は小胞体ストレス応答転写因子ATF4の直接ターゲットである2008
- Author(s)
  佐竹千尋, 石原寿光, 岡芳知, 他6名
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] Essential role of translational control in β cell survival under stress conditions2008
- Author(s)
  Ishihara H
- Organizer
  Asia Islet Biology & Incretin Symposium
- Place of Presentation
  Incheon, Korea
- Year and Date
  2008-10-18
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 翻訳抑制因子4E-BP1は小胞体ストレス応答転写因子ATF4の直接のターゲットである2008
- Author(s)
  佐竹千尋、石原寿光、田村明、山田高弘山口賢、冨永竜、宗像佑一郎、檜尾好徳、荻原健英、鈴木進、片桐秀樹、岡芳知
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 翻訳抑制因子4E-BP1は、慢性的な小胞体ストレス下の膵β細胞において、翻訳抑制を介して細胞を保護する2008
- Author(s)
  山口賢, 石原寿光, 岡芳知, 他7名
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] 2型糖尿病の発症における膵β細胞障害2008
- Author(s)
  石原寿光
- Organizer
  第42回糖尿病学の進歩
- Place of Presentation
  高松市
- Year and Date
  2008-02-15
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 翻訳抑制因子4E-BP1は、慢性的な小胞体ストレス下の膵β細胞において翻訳抑制を介して細胞を保護する2008
- Author(s)
  山口賢、石原寿光、田村明、山田高弘、冨永竜、宗像佑一郎、檜尾好徳、荻原健英、鈴木進、片桐秀樹、岡芳知
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞特異的小胞体ストレス応答の検討2007
- Author(s)
  宗像佑一郎、石原寿光、田村明、山田高弘、山口賢、佐竹千尋、薄井正寛、冨永竜、檜尾好徳、荻原健英、片桐秀樹、岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 翻訳抑制因子4E-BP1の欠損は、小胞体ストレスによる膵β細胞障害を悪化させる2007
- Author(s)
  山口賢, 石原寿光, 田村明, 山田高弘, 佐竹千尋, 薄井正寛, 冨永竜, 檜尾好徳, 荻原健英, 鈴木進, 片桐秀樹, 岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞における小胞体ストレスによる翻訳抑制因子4E-BP1発現誘導機構2007
- Author(s)
  薄井正寛、佐竹千尋、石原寿光、田村明、山田高弘、山口賢、冨永竜、宗像佑一郎、檜尾好徳、荻原健英、鈴木進、片桐秀樹、岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] An essential role of the translational suppressor 4E-BP1 in pancreatic β cell survival under ER stress2007
- Author(s)
  Ishihara H
- Organizer
  日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 膵β細胞特異的小胞体ストレス応答の検討2007
- Author(s)
  宗像佑一郎, 石原寿光, 田村明, 山田高弘, 山口賢, 佐竹千尋, 薄井正寛, 冨永竜, 檜尾好徳, 荻原健英, 鈴木進, 片桐秀樹, 岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] 膵β細胞における小胞体ストレスによる翻訳抑制因子4E-BP1発現誘導機構2007
- Author(s)
  薄井正寛, 佐竹千尋, 石原寿光, 田村明, 山田高弘, 山口賢, 冨永竜, 宗像佑一郎, 檜尾好徳, 荻原健英, 鈴木進, 片桐秀樹, 岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] 翻訳抑制因子4E-BP1の欠損は小胞体ストレスによる膵β細胞障害を悪化させる2007
- Author(s)
  山口賢、石原寿光、田村明、山田高弘、佐竹千尋、薄井正寛、冨永竜、檜尾好徳、荻原健英、鈴木進、片桐秀樹、岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] Transcription factor TFII-I binds to WFS1 protein and dissociates in response to endoplasmic reticulum stress.2007
- Author(s)
  山口賢, 石原寿光, 岡芳知
- Organizer
  The 67th scientific sessions of American Diabetes Association
- Place of Presentation
  Chicago
- Year and Date
  2007-06-23
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] 翻訳抑制因子4E-BP1の欠損は、小胞体ストレスによる細胞障害を悪化させる2007
- Author(s)
  山口賢, 石原寿光, 田村明, 山田高弘, 佐竹千尋, 薄井正寛, 冨永竜, 檜尾好徳, 荻原健英, 鈴木進, 片桐秀樹, 岡芳知
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] Transcription factor TFII-I binds to WFS1 protein and dissociates in response to endoplasmic reticulum stress2007
- Author(s)
  Yamaguchi S, Ishihara H, Oka Y
- Organizer
  The 67th scientific sessions of American Diabetes Association
- Place of Presentation
  Chicago
- Year and Date
  2007-06-23
- Data Source
  KAKENHI-PROJECT-19590300
[Presentation] The Translational Suppressor 4E-BP1 is a Critical Component of the ER Stress Response Involved in Component of the ER Stress Response Involved in Pancreatic b Cell Survival2007
- Author(s)
  Hisamitsu Ishihara, Suguru Yamaguchi, Yoshitomo Oka
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19209034
[Presentation] Generation of a MIN6 beta-cell clone horboring platform for introduction of an inducible expression unit by recombinase-mediated cassette exchange
- Author(s)
  Ishihara H, Furukawa A, Tanaka A, Otsuka Y, Yamaguchi S
- Organizer
  The 74th Scientific Sessions of American Diabetes Association
- Place of Presentation
  San Francisco （USA）
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] 腹部症状を契機に発症した抗インスリン抗体比較的強陽性の劇症1型糖尿病の1例
- Author(s)
  小須田南，岡本真由美, 荒井秀仁, 東海林忍, 山口賢, 江頭富士子, 石原寿光
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] DPP-4阻害薬とSU薬による遷延性低血糖に対してオクトレオチド投与が奏効した症例
- Author(s)
  古川麻美，山口賢, 池島碧, 田中彩, 上野のぶ子, 東海林忍, 江頭富士子, 岡本真由美, 吉田好徳, 阿部雅紀, 石原寿光
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591343
[Presentation] Modulation of glucagon and insulin secretion by DPP-4 and DPP-4 inhibitors
- Author(s)
  Yamaguchi S, Otsuka Y, Ishihara H
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Invited
- Data Source
  KAKENHI-PROJECT-24591343
[]
[]
[]

1. HINOKIO Yoshinori (10282071)

# of Collaborated Projects: 8 results

# of Collaborated Products: 2 results
2. ISHIGAKI Yasusi (50375002)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
3. SUZUKI Susumu (70216399)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
4. HIRAI Masashi (80312578)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
5. KATAGIRI Hideki (00344664)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
6. OKA Yoshitomo (70175256)

# of Collaborated Projects: 5 results

# of Collaborated Products: 36 results
7. TAMURA Akira (00375023)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
8. YAMAGUCHI Suguru (70451614)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
9. YAMADA Tetsuya (90400374)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
10. OKAMOTO Mayumi (80349993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. MIYAGI Taeko (50006110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. TAKAHASHI Kazuma (60292215)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SAGAWA Chigako (30459896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. CHOI Mihwa (30571012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. MAKISHIMA Makoto (70346146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. OGIHARA Takehide (40361068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OTSUKA Yuichiro (40748399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 谷澤幸生 (00217142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 藤城緑 (50420211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. 渡邉健太郎 (80373017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 小須田南 (40811609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
22. 齊藤一樹 (90962879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NAKATSU Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. KUSHIYAMA Akifumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 迫田秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 高橋和真

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
27. 谷沢幸生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 森和俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 森博幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 福嶋俊明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ishihara hisamitsu 石原 寿光

ISHIHARA Hisamitsu 石原 寿光

Research Projects

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Molecular mechanisms underlying metabolism-secretion coupling in endocrine cells of the islets of LangerhansPrincipal Investigator

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Metabolic features of hormone secreting cells in pancreatic islets and analyses of their dysfunction using pseudo-isletsPrincipal Investigator

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Elucidation of insulin secretory mechanisms through large scale generation of genetically-modified insulin secreting cells and omics analysisPrincipal Investigator

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Development of an efficient method for generation of genetically modified insulin secreting cells and its application for studies on insulin secretionPrincipal Investigator

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Analysis of glucagon seceretion mechanisms and its modulation by anti-diabetes drugsPrincipal Investigator

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Molecular mechanisms of pancreaticβ-cell failure and insulin resistance due to impaired ER stress responsePrincipal Investigator

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The molecular mechanisms of transcriptional and translational control of stress responses in pancreatic β cellsPrincipal Investigator

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Molecular Mechanisms for Pancreatic Islet Disfunction in Development of Diabetes Mellitus-a study using WFS1 knockout micePrincipal Investigator

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ishihara hisamitsu 石原寿光

ISHIHARA Hisamitsu 石原寿光