Kasamatsu Atsushi 笠松厚志

… Alternative Names

KASAMATSU Atsushi 笠松厚志

Less

Researcher Number	60375730
Other IDs	https://orcid.org/0000-0002-8054-2584
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 千葉大学, 大学院医学研究院, 准教授 2018 – 2023: 千葉大学, 医学部附属病院, 講師 2015: 千葉大学, 医学部附属病院, 講師 2015: 千葉大学, 医学部付属病院, 講師 2014: 千葉大学, 医学部付属病院, 助教 2012 – 2014: 千葉大学, 医学部附属病院, 助教 2009 – 2010: Chiba University, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Dental engineering/Regenerative dentistry / Medium-sized Section 57:Oral science and related fields / Surgical dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 口腔癌 / 環状RNA / non coding RNA / ROCK作用薬 / 唾液腺再生療法 / 長期培養 / 唾液腺 / 唾液腺再生医療 / CAF / コラーゲンバリア … More / コラーゲンガイドウェイ / LH2 / ノンコーディングRNA / 人工合成環状RNA / microRNA / エクソソーム / CircRNA Array / circRNA miRNA / circRNA Array / miRNA / circRNA / non codingRNA / Rho Kinase 作用薬 / Rho Kinase　作用薬 / Rock作用薬 / 口唇腺細胞 / インクレチン分泌 / インスリン分泌 / 糖代謝制御 / 生理学 / 糖代謝 / 口腔内消化 … More Except Principal Investigator 口腔癌 / LH2 / 口腔扁平上皮癌 / Plod2 / コラーゲンクロスリンク / NGS / Lysyl Hydroxylase 2 / スーパーエンハンサー / CRISPR/Cas9 / 口腔癌細胞の顎骨浸潤 / シスプラチン / ATAC-seq / リシン水酸化酵素 2 / 咀嚼力 / オーラルフレイル / 食道癌 / ゲノムワイド機能欠損型スクリーニング法 / CRISPER sgRNAライブラリー / 放射線耐性 / CRISPR スクリーニング法 / CRISPRscreening / CRISPR / 次世代シーケンシング / single cell RNA sequence / heterogeneity / 薬剤耐性担当因子 / シングルセル解析 / scRNA-seq解析 / 抗癌剤耐性 / 免疫チェックポイント阻害薬 / LH2-derived collagen線維 / inhibitor / tamoxifen / collagen barrier / LH2-conditional KOマウス / リシン水酸化酵素2 / Collagen cross-link / Collagen Barrier / Collagen Highway / collagen / collagen cross-link / コンディショナルノックアウトマウス / 口腔癌治療抵抗性 / long non coding RNA / miRNA / H3K27 / Chip-seq法 / スーパーエンハンサー(SE) / エピジェネティックな修飾 / H3K27ac / 機能特異性 / 疾患特異性 / 組織特異性 / ChIP-seq 法 / 唾液腺細胞治療 / 唾液腺長期安定培養法 / first in human / 高度滅菌培養 / 唾液腺機能回復 / 頭頸部放射線治療 / 口唇腺 / KOマウス / ナノインデンテーション試験 / クロスリンク解析 / GFP標識癌細胞 / 転移モデル / 低酸素応答 / HIF1-α / HIF-1α / 胎生致死 / PLOD2 / ノックアウトマウス / kinesin family（KIF） / 微小管作動性制御 / タキサン系抗癌剤 / KIF4A / 唾液腺再生 / direct reprogramming / 唾液腺萎縮 / long non-coding RNA / long non-cording RNA Less

An attempt to improve the effectiveness of esophageal cancer treatment by quantification of masticatory strength and active intervention
- Principal Investigator
  
  松本泰典
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba University
口腔がん細胞の顎骨浸潤に対するLH2関連分子ネットワークの解明と制御薬剤の開発
- Principal Investigator
  
  中嶋大
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
機能性RNA時間的階層性の理解に基づく口腔癌・シスプラチン耐性機構の解明
- Principal Investigator
  
  伊豫田学
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
LH2活性制御に基づくコラーゲン架橋強化誘導による新規骨再生促進療法の開発
- Principal Investigator
  
  福嶋玲雄
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Extracellular Components to Disrupt Cancer ProgressionPrincipal Investigator
- Principal Investigator
  
  笠松厚志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Chiba University
LH2-Colをターゲットとする免疫チェックポイント耐性克服療法の開発
- Principal Investigator
  
  中嶋大
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Heterogeneityに着目した口腔癌抗癌剤耐性機構の解明と制御薬の開発
- Principal Investigator
  
  坂本洋右
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
CRISPR/Cas9ノックアウトスクリーニングによる放射線耐性メカニズムの同定
- Principal Investigator
  
  伊豫田学
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Elucidation of the mechanism of inhibition of cancer progression and development of new drugs by artificial synthetic cyclic RNAsPrincipal Investigator
- Principal Investigator
  
  笠松厚志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Collagen to Overcome Treatment-Resistant Cancer Phenotypes.
- Principal Investigator
  
  Uzawa Katsuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Chiba University
CRISPRスクリーニング法を用いたセツキシマブ耐性分子機構の解明
- Principal Investigator
  
  小池一幸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Elucidation of the role of non-coding RNA adsorbed cyclic RNA in cancer growth invasion and metastasis.Principal Investigator
- Principal Investigator
  
  Kasamatsu Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
口腔癌悪性度を決定するスーパーエンハンサーによる系統的転写制御機構の解明
- Principal Investigator
  
  椎葉正史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Evaluate changes in collagen cross-linking in lysyl hydroxylase 2 knockout mice and elucidate the role of PLOD2 in cancer metastasis
- Principal Investigator
  
  Nakashima Dai
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Development study of normal salivary gland cell function maintenance, long-term mass culture method and completely new autotransplantation method
- Principal Investigator
  
  HIGO MORIHIRO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Analysis of the role of the taxane anti-cancer drugs resistance of KIF genes and the development of treatment for overcoming resistance
- Principal Investigator
  
  HIDEKI TANZAWA
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Establishment of long-term stability culturing system for salivary gland cellsPrincipal Investigator
- Principal Investigator
  
  KASAMATSU Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Chiba University
Studies of the clinical significance and the role of long non coding RNA in oral cancer.
- Principal Investigator
  
  SHIIBA MASASHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Development of induction method using adipose-derived mesenchymal stem cells by transcription factor group for salivary gland differentiation
- Principal Investigator
  
  UZAWA KATSUHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Establishment of novel culturing system for salivary gland cellsPrincipal Investigator
- Principal Investigator
  
  KASAMATSU Atsushi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Chiba University
Roles of intraoral digestion on regulation of glucose metabolismPrincipal Investigator
- Principal Investigator
  
  KASAMATSU Atsushi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University

All 2020 2019

All Journal Article Presentation

[Journal Article] Deficiency of lysyl hydroxylase 2 in mice causes systemic endoplasmic reticulum stress leading to early embryonic lethality2019
- Author(s)
  笠松厚志
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 512 Issue: 3 Pages: 486-491
- DOI
  10.1016/j.bbrc.2019.03.091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09717, KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K09665
[Presentation] 安藤壽晃癌抑制型環状RNA: 口腔癌誘発性マイクロRNAの特異的吸着効果による新規診断法の開発2020
- Author(s)
  安藤壽晃　鵜澤一弘　笠松厚志　田中希　野淵嵩史　駒綾香　大島早智　伊豫田学　中嶋大　坂本洋右　椎葉正史
- Organizer
  日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-19H03847

1. UZAWA KATSUHIRO (30302558)

# of Collaborated Projects: 12 results

# of Collaborated Products: 1 results
2. Nakashima Dai (50431747)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
3. TANZAWA HIDEKI (50236775)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 齋藤智昭 (40833554)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. SHIIBA MASASHI (20301096)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 小池一幸 (10618060)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 坂本洋右 (50451745)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. 福嶋玲雄 (00833576)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 伊豫田学 (40431746)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. HIGO MORIHIRO (60724383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 関直彦 (50345013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 小池博文 (10595995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 宮本勲 (00741836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田村裕 (50263174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 菅波晃子 (10527922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 加瀬裕太郎 (51000509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 松本泰典 (80738831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kasamatsu Atsushi 笠松 厚志

KASAMATSU Atsushi 笠松 厚志

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Extracellular Components to Disrupt Cancer ProgressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of inhibition of cancer progression and development of new drugs by artificial synthetic cyclic RNAsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the role of non-coding RNA adsorbed cyclic RNA in cancer growth invasion and metastasis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Kasamatsu Atsushi 笠松厚志

KASAMATSU Atsushi 笠松厚志