Kasamatsu Atsushi 笠松厚志

… Alternative Names

KASAMATSU Atsushi 笠松厚志

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Researcher Number	60375730
Other IDs	https://orcid.org/0000-0002-8054-2584
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2024: 千葉大学, 大学院医学研究院, 准教授 2018 – 2023: 千葉大学, 医学部附属病院, 講師 2015: 千葉大学, 医学部附属病院, 講師 2015: 千葉大学, 医学部付属病院, 講師 2014: 千葉大学, 医学部付属病院, 助教 2012 – 2014: 千葉大学, 医学部附属病院, 助教 2009 – 2010: Chiba University, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Dental engineering/Regenerative dentistry / Medium-sized Section 57:Oral science and related fields / Surgical dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 口腔癌 / 環状RNA / non coding RNA / ROCK作用薬 / 唾液腺再生療法 / 長期培養 / 唾液腺 / 唾液腺再生医療 / CAF / コラーゲンバリア … More / コラーゲンガイドウェイ / LH2 / ノンコーディングRNA / 人工合成環状RNA / microRNA / エクソソーム / CircRNA Array / circRNA miRNA / circRNA Array / miRNA / circRNA / non codingRNA / Rho Kinase 作用薬 / Rho Kinase　作用薬 / Rock作用薬 / 口唇腺細胞 / インクレチン分泌 / インスリン分泌 / 糖代謝制御 / 生理学 / 糖代謝 / 口腔内消化 … More Except Principal Investigator 口腔扁平上皮癌 / 口腔癌 / Plod2 / コラーゲンクロスリンク / LH2 / NGS / Lysyl Hydroxylase 2 / CRISPR/Cas9 / ゲノムワイド機能欠損型スクリーニング法 / CRISPER sgRNAライブラリー / 放射線耐性 / CRISPR スクリーニング法 / CRISPRscreening / CRISPR / 次世代シーケンシング / single cell RNA sequence / heterogeneity / 薬剤耐性担当因子 / シングルセル解析 / scRNA-seq解析 / 抗癌剤耐性 / 免疫チェックポイント阻害薬 / LH2-derived collagen線維 / inhibitor / tamoxifen / collagen barrier / LH2-conditional KOマウス / リシン水酸化酵素2 / Collagen cross-link / Collagen Barrier / Collagen Highway / collagen / collagen cross-link / コンディショナルノックアウトマウス / 口腔癌治療抵抗性 / long non coding RNA / miRNA / H3K27 / Chip-seq法 / スーパーエンハンサー(SE) / エピジェネティックな修飾 / H3K27ac / 機能特異性 / 疾患特異性 / 組織特異性 / ChIP-seq 法 / スーパーエンハンサー / 唾液腺細胞治療 / 唾液腺長期安定培養法 / first in human / 高度滅菌培養 / 唾液腺機能回復 / 頭頸部放射線治療 / 口唇腺 / KOマウス / ナノインデンテーション試験 / クロスリンク解析 / GFP標識癌細胞 / 転移モデル / 低酸素応答 / HIF1-α / HIF-1α / 胎生致死 / PLOD2 / ノックアウトマウス / kinesin family（KIF） / 微小管作動性制御 / タキサン系抗癌剤 / KIF4A / 唾液腺再生 / direct reprogramming / 唾液腺萎縮 / long non-coding RNA / long non-cording RNA Less

Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Extracellular Components to Disrupt Cancer ProgressionPrincipal Investigator
- Principal Investigator
  
  笠松厚志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Chiba University
LH2-Colをターゲットとする免疫チェックポイント耐性克服療法の開発
- Principal Investigator
  
  中嶋大
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Heterogeneityに着目した口腔癌抗癌剤耐性機構の解明と制御薬の開発
- Principal Investigator
  
  坂本洋右
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
CRISPR/Cas9ノックアウトスクリーニングによる放射線耐性メカニズムの同定
- Principal Investigator
  
  伊豫田学
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Elucidation of the mechanism of inhibition of cancer progression and development of new drugs by artificial synthetic cyclic RNAsPrincipal Investigator
- Principal Investigator
  
  笠松厚志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Collagen to Overcome Treatment-Resistant Cancer Phenotypes.
- Principal Investigator
  
  Uzawa Katsuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Chiba University
CRISPRスクリーニング法を用いたセツキシマブ耐性分子機構の解明
- Principal Investigator
  
  小池一幸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Elucidation of the role of non-coding RNA adsorbed cyclic RNA in cancer growth invasion and metastasis.Principal Investigator
- Principal Investigator
  
  Kasamatsu Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
口腔癌悪性度を決定するスーパーエンハンサーによる系統的転写制御機構の解明
- Principal Investigator
  
  椎葉正史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Evaluate changes in collagen cross-linking in lysyl hydroxylase 2 knockout mice and elucidate the role of PLOD2 in cancer metastasis
- Principal Investigator
  
  Nakashima Dai
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Development study of normal salivary gland cell function maintenance, long-term mass culture method and completely new autotransplantation method
- Principal Investigator
  
  HIGO MORIHIRO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Chiba University
Analysis of the role of the taxane anti-cancer drugs resistance of KIF genes and the development of treatment for overcoming resistance
- Principal Investigator
  
  HIDEKI TANZAWA
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Establishment of long-term stability culturing system for salivary gland cellsPrincipal Investigator
- Principal Investigator
  
  KASAMATSU Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Chiba University
Studies of the clinical significance and the role of long non coding RNA in oral cancer.
- Principal Investigator
  
  SHIIBA MASASHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Development of induction method using adipose-derived mesenchymal stem cells by transcription factor group for salivary gland differentiation
- Principal Investigator
  
  UZAWA KATSUHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University
Establishment of novel culturing system for salivary gland cellsPrincipal Investigator
- Principal Investigator
  
  KASAMATSU Atsushi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Chiba University
Roles of intraoral digestion on regulation of glucose metabolismPrincipal Investigator
- Principal Investigator
  
  KASAMATSU Atsushi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Chiba University

All 2020 2019

All Journal Article Presentation

[Journal Article] Deficiency of lysyl hydroxylase 2 in mice causes systemic endoplasmic reticulum stress leading to early embryonic lethality2019
- Author(s)
  笠松厚志
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 512 Issue: 3 Pages: 486-491
- DOI
  10.1016/j.bbrc.2019.03.091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09717, KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K09665
[Presentation] 安藤壽晃癌抑制型環状RNA: 口腔癌誘発性マイクロRNAの特異的吸着効果による新規診断法の開発2020
- Author(s)
  安藤壽晃　鵜澤一弘　笠松厚志　田中希　野淵嵩史　駒綾香　大島早智　伊豫田学　中嶋大　坂本洋右　椎葉正史
- Organizer
  日本口腔外科学会
- Data Source
  KAKENHI-PROJECT-19H03847

1. UZAWA KATSUHIRO (30302558)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
2. TANZAWA HIDEKI (50236775)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. Nakashima Dai (50431747)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. SHIIBA MASASHI (20301096)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 小池一幸 (10618060)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 坂本洋右 (50451745)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. HIGO MORIHIRO (60724383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 齋藤智昭 (40833554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 伊豫田学 (40431746)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 小池博文 (10595995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宮本勲 (00741836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 福嶋玲雄 (00833576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田村裕 (50263174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 菅波晃子 (10527922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 関直彦 (50345013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 加瀬裕太郎 (51000509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kasamatsu Atsushi 笠松 厚志

KASAMATSU Atsushi 笠松 厚志

Research Projects

Research Products

Co-Researchers

Japan-US Research Collaboration on the Development of a Novel Therapeutic Strategy Targeting the Cancer-Associated Extracellular Components to Disrupt Cancer ProgressionPrincipal Investigator

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Elucidation of the mechanism of inhibition of cancer progression and development of new drugs by artificial synthetic cyclic RNAsPrincipal Investigator

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Elucidation of the role of non-coding RNA adsorbed cyclic RNA in cancer growth invasion and metastasis.Principal Investigator

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Establishment of long-term stability culturing system for salivary gland cellsPrincipal Investigator

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Principal Investigator

Kasamatsu Atsushi 笠松厚志

KASAMATSU Atsushi 笠松厚志