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Yamamoto Akiko  山本 明子

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YAMAMOTO Akiko  山本 明子

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Researcher Number 60402385
Other IDs
External Links
Affiliation (Current) 2025: 名古屋大学, 総合保健体育科学センター, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 名古屋大学, 総合保健体育科学センター, 教授
2009 – 2019: 名古屋大学, 総合保健体育科学センター, 准教授
2012 – 2014: 名古屋大学, 学内共同利用施設等, 准教授
2007 – 2009: 名古屋大学, 総合保健体育科学センター, 助教
2005 – 2006: Nagoya University, Research Center of Health, Physical Fitness, and Sports, Research Associate, 総合保健体育科学センター, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology / Pathological medical chemistry / Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53010:Gastroenterology-related / General physiology / Biological Sciences
Keywords
Principal Investigator
膵外分泌 / 膵導管細胞 / 生理学 / 脂肪酸 / 単離膵管 / 単離小葉間膵管 / GLP-1 / カルニチン / 中鎖脂肪酸 / 膵臓導管細胞 … More / 亜鉛トランスポーター / 膵液分泌 / 亜鉛 / 胆汁酸 / GPR40 / NHE (Na^+-H^+ exchange) / CFTR (cystic fibrosis transmembrane conductance regulator) / NHE(Na^+-H^+ exchange) / CFTR(cystic fibrosis transmembrane conductance regulator) / ナトリウム―プロトン交換輸送体 / 抗エストロゲン剤 / 嚢胞性線維症 / 膵臓学 / 胆道学 … More
Except Principal Investigator
CFTR / 膵導管細胞 / 慢性膵炎 / 単離小葉間膵管 / cystic fibrosis / cut-off effect / Na^+-H^+ exchange / 嚢胞性線維症 / SLC26A6 / 汗中Cl^-濃度 / 膵管 / モルモット単離小葉間膵管 / アルコール / 短鎖アルコール / 多発性嚢胞腎症 / ΔFマウス / 小葉間膵管 / 膵液 / 細胞内pH / 粘膜上皮 / 膵がん / IPMN / 気管支 / iPS細胞 / 胆管上皮細胞 / 胆管 / CFTRバリアント / 内科 / 生理学 / 細胞・組織 / 遺伝子 / オルガノイド / 腸管オルガノイド / transgenic mice / sweat CI concentration / Cl-HCO_3^- exchange / HCO_3^-conductance / HCO_3^-transport / pancreatic duct cell / 管腔膜 / Cl^--HCO_3^- exchange / 遺伝子変異マウス / Cl^--HCO_3^-交換 / HCO_3^-コンダクタンス / HCO_3^-輸送 / short-chain alcohol / interlobular pancreatic duct / sweat chloride / chronic pancreatitis / 過分泌 / エタノール / CFTR多型 / アルコール性慢性膵炎 / イオンチャネル / 多型 / CFTR遺伝子変異 / 膵液pH / 精密Cl^-電極 / 嚢胞線維症 / BMI1 / LGR5 / 膵炎 / ZSCAN4 / 幹/前駆細胞 / 膵臓 / 幹細胞マーカー / 膵組織幹細胞 / 組織幹細胞 / 膵組織再生 / Primary cilia / primary cilia / Panc-1細胞 / Ca^<2+>チャネル / 膵石 / 溶液分泌 / secretin / fibrocystin / polycystic kidneyラット / 細胞内Ca^<2+>濃度 / 線毛 / PCKラット / microperfusion / カルシウム輸送体 / 膵導管上皮 / 膵石症 / 管腔内pH / Na^+-H^+exchange / 重炭酸イオン輸送 / Cl^--HCO_3^-exchanger / AE2 / シミュレーションモデル / コンピュータシミュレーション / HCO_3^-分泌 / NHE3 / 導管細胞機能 / 膵炎発症機構 / 膵石形成機序 / アクアポリン水チャネル / 導管細胞 / AQP / 細胞内局在 / 膜蛋白 / 低分子量G蛋白 / SLC26輸送体 / STASドメイン / 低分子量G蛋白質 / SLC26 / 膜輸送複合体 / 転写調節 / 指先汗クロライド試験 / 汗中Cl-濃度 / 遺伝子多型 / 遺伝子変異 / 非翻訳領域 / プロモーター領域 / siRNA法 / ノックアウトマウス / HCO_3輸送 / SLC26A6 Cl-HCO_3交換輸送体 / 膵外分泌 / HCO_3^-チャネル / HCO_3^-透過性 / 膜電位 / 重炭酸イオン Less
  • Research Projects

    (18 results)
  • Research Products

    (189 results)
  • Co-Researchers

    (24 People)
  •  膵IPMNにおけるCFTR遺伝子変異と悪性化の関係解明および治療応用

    • Principal Investigator
      川嶋 啓揮
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Nagoya University
  •  GLP-1の膵外分泌制御機能の解明と治療的応用Principal Investigator

    • Principal Investigator
      山本 明子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nagoya University
  •  Study of cystic fibrosis using pancreatic ductal and biliary epithelia from human pluripotent stem cells

    • Principal Investigator
      Ishiguro Hiroshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nagoya University
  •  Establishment of treatment for pancreatic exocrine insufficiency and nutritional disorders by using combination of carnitine and medium-chain fatty acids.Principal Investigator

    • Principal Investigator
      YAMAMOTO AKIKO
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nagoya University
  •  A study to establish individualized medicine of cystic fibrosis using intestinal organoids derived from patients

    • Principal Investigator
      Ishiguro Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Role of zinc in intestinal-pancreatic circulation and pancreatic functionPrincipal Investigator

    • Principal Investigator
      Yamamoto Akiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Bile acid and gut luminal environment modulates fatty-acid sensing by GPR40Principal Investigator

    • Principal Investigator
      YAMAMOTO AKIKO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  A study of molecular pathogenesis of chronic pancreatitis by using polycystic kidney rat

    • Principal Investigator
      ISHIGURO Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Identification of endocrine and exocrine stem/protenitor cells in the pancreas.

    • Principal Investigator
      KO Shigeru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Anti-estrogen regulates proton ion: A study looking for a new therapy of cystic fibrosis.Principal Investigator

    • Principal Investigator
      YAMAMOTO Akiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Molecular pathogenesis of the mucosal lesion due to the dysfunction of NHE3-CFTR transportsome

    • Principal Investigator
      KONDO Takaharu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Chubu University
      Nagoya University
  •  Mechanisms for Ca2+ absorption by pancreatic ductal epithelium : A study looking for a new strategy to prevent pancreatic stone formation.

    • Principal Investigator
      ISHIGURO Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  CFTR-SLC26輸送体複合体のイオン輸送機能における低分子量G蛋白質の役割

    • Principal Investigator
      洪 繁
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  The roles of mislocalization of membrane proteins in the development of chronic pancreatitis

    • Principal Investigator
      KO Shigeru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Pathophysiology of mucosal lesion caused by defects of epithelial HCO_3^--CO_2 transport

    • Principal Investigator
      KONDO Takaharu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya University
  •  Role of CFTR gene expression in the pathogenesis of chronic pancreatitis : regulation by non-coding region

    • Principal Investigator
      ISHIGURO Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Physiological characteristics and molecular identity of HCO_3-conductance in pancreatic duct cells.

    • Principal Investigator
      ISHIGURO HIROSHI
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Nagoya University
  •  Ethanol/lipid metabolism, dysfunction of ion transport, and pathogenesis of alcoholic pancreatitis

    • Principal Investigator
      KONDO Takaharu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] Regulation of pancreatic fluid and electrolyte secretion, The Pancreas: Biology and Physiology2021

    • Author(s)
      Ishiguro H, Yamaguchi M, Yamamoto A
    • Total Pages
      11
    • Publisher
      American Pancreatic Association and Michigan Publishing
    • ISBN
      9781607857198
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Book] 嚢胞線維症の診療の手引き【改定2版】2018

    • Author(s)
      山本明子、石黒洋 他
    • Total Pages
      313
    • Publisher
      名古屋大学消費生活協同組合 印刷部
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Book] ニュー運動生理学(宮村実晴 編)2014

    • Author(s)
      石黒 洋、山本明子
    • Total Pages
      376
    • Publisher
      真興交易医書出版部
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Book] 膵嚢胞線維症の診療の手引き2008

    • Author(s)
      大槻眞、成瀬達、近藤孝晴、石黒洋、山本明子、洪繁(他)
    • Total Pages
      74
    • Publisher
      アークメディア(東京)
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Book] 膵嚢胞線維症の診療の手引き2008

    • Author(s)
      大槻眞, 成瀬達, 近藤孝晴, 石黒洋, 山本明子, 洪繁, 他
    • Total Pages
      74
    • Publisher
      アークメディア
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Book] 膵嚢胞線維症の診療の手引き2008

    • Author(s)
      大槻眞、成瀬達、近藤孝晴、石黒洋、山本明子、洪 繁、他
    • Total Pages
      74
    • Publisher
      アークメディア(東京)
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Book] 胆嚢胞線維症の診療の手引き2008

    • Author(s)
      大槻波, 成瀬達, 石黒洋, 山本明子, 藤木理代, 他
    • Total Pages
      74
    • Publisher
      アークメディア
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Book] CFTRの機能異常と慢性膵炎2007

    • Author(s)
      石黒洋、近藤孝晴、山本明子、成瀬達
    • Publisher
      Annual Review消化器2007(中外医学社)
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Book] CFTRの機能異常と慢性膵炎2007

    • Author(s)
      石黒洋、近藤孝晴、山本明子、成瀬達
    • Publisher
      Annual Review消化器2007(中外医学社)
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] Bicarbonate transport of airway surface epithelia in luminally perfused mice bronchioles2022

    • Author(s)
      Liu L, Yamamoto A, Yamaguchi M, Taniguchi I, Nomura N, Nakakuki M, Kozawa Y, Fukuyasu T, Higuchi M, Niwa E, Tamada T, Ishiguro H
    • Journal Title

      J Physiol Sci

      Volume: 72 Issue: 1 Pages: 1-16

    • DOI

      10.1186/s12576-022-00828-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08285, KAKENHI-PROJECT-21K08148
  • [Journal Article] 膵導管細胞の病態生理と嚢胞性線維症2022

    • Author(s)
      石黒 洋、山口 誠、山本明子
    • Journal Title

      胆と膵

      Volume: 43(8) Pages: 743-750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Journal Article] 膵嚢胞線維症(嚢胞性線維症)2021

    • Author(s)
      成瀬 達、中莖みゆき、藤木理代、近藤志保、小澤祐加、山本明子、石黒 洋
    • Journal Title

      胆と膵

      Volume: 42 Pages: 937-941

    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Journal Article] Cystic fibrosis with focal biliary cirrhosis and portal hypertension in Japan: a case report2021

    • Author(s)
      山本明子、伊藤孝一、成瀬 達、服部日出雄、中莖みゆき、藤木理代、石黒 洋
    • Journal Title

      Nippon Shokakibyo Gakkai Zasshi

      Volume: 118 Issue: 7 Pages: 686-697

    • DOI

      10.11405/nisshoshi.118.686

    • NAID

      130008064416

    • ISSN
      0446-6586, 1349-7693
    • Year and Date
      2021-07-10
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Journal Article] Regulation of Pancreatic Fluid and Electrolyte Secretion2021

    • Author(s)
      Ishiguro H, Yamaguchi M, Yamamoto A
    • Journal Title

      Pancreapedia Exocrine Pancreas Knowledge Base

      Volume: 1 Pages: 1-13

    • DOI

      10.3998/panc.2021.05

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Journal Article] Pancreatic Bicarbonate Secretion2020

    • Author(s)
      Ishiguro H, Yamamoto A, Steward MC
    • Journal Title

      Encyclopedia of Gastroenterology 2nd Edition

      Volume: 4 Pages: 24-29

    • DOI

      10.1016/b978-0-12-801238-3.65645-3

    • ISBN
      9780128187289
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Journal Article] 難病研究の進歩 嚢胞性線維症2020

    • Author(s)
      石黒 洋、相馬義郎、山本明子
    • Journal Title

      生体の科学

      Volume: 71 Pages: 436-437

    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Journal Article] アルコール性膵障害の分子機序2018

    • Author(s)
      石黒 洋、山本明子
    • Journal Title

      肝胆膵

      Volume: 76 Pages: 121-126

    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Journal Article] 【知っておこう!遺伝性消化器疾患】 嚢胞性線維症2018

    • Author(s)
      石黒 洋、 連 利博、 丸山 慎介、眞田 幸弘、山本 明子
    • Journal Title

      消化器内視鏡

      Volume: 30 Pages: 1090-1095

    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Journal Article] 【肝胆膵とアルコール-serendipityを目指して-】 アルコール性膵炎 アルコール性膵障害の分子機序2018

    • Author(s)
      石黒 洋、山本明子
    • Journal Title

      肝・胆・膵

      Volume: 76 Pages: 121-126

    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Journal Article] 知っておこう遺伝性消化器疾患:嚢胞性線維症2018

    • Author(s)
      石黒 洋、連 利博、丸山慎介、眞田幸弘、山本明子
    • Journal Title

      消化器内視鏡

      Volume: 30 Pages: 1090-1095

    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Journal Article] Cystic Fibrosisにおける膵機能の評価と治療2017

    • Author(s)
      石黒 洋、藤木理代、近藤志保、中莖みゆき、小澤祐加、谷口いつか、成瀬 達、山本明子
    • Journal Title

      膵臓

      Volume: 32 Pages: 699-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Journal Article] Caffeine Inhibits Fluid Secretion by Interlobular Ducts From Guinea Pig Pancreas.2017

    • Author(s)
      Mochimaru Y, Yamamoto A, Nakakuki M, Yamaguchi M, Taniguchi I, Ishiguro H.
    • Journal Title

      Pancreas

      Volume: 46 Issue: 4 Pages: 549-556

    • DOI

      10.1097/mpa.0000000000000782

    • Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Journal Article] Bicarbonate-rich fluid secretion predicted by a computational model of guinea-pig pancreatic duct epithelium.2017

    • Author(s)
      Yamaguchi M, Steward MC, Smallbone K, Sohma Y, Yamamoto A, Ko SBH, Kondo T, Ishiguro H
    • Journal Title

      Journal of Physiology

      Volume: 595 Issue: 6 Pages: 1947-1972

    • DOI

      10.1113/jp273306

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293049, KAKENHI-PROJECT-15K15035, KAKENHI-PROJECT-16K09392
  • [Journal Article] 知っておきたい稀な肝胆膵疾患 嚢胞性線維症2016

    • Author(s)
      石黒 洋、藤木理代、中莖みゆき、近藤志保、谷口いつか、宇佐見祐加、成瀬 達、山本明子
    • Journal Title

      肝胆膵

      Volume: 73 Pages: 451-459

    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Journal Article] Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese.2015

    • Author(s)
      S. Kondo, K. Fujiki, S.B. Ko, A. Yamamoto, M Nakakuki, Y. Ito, N. Shcheynikov, M. Kitagawa, S. Naruse, H. Ishiguro.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 309 Issue: 4 Pages: G260-G269

    • DOI

      10.1152/ajpgi.00015.2014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Journal Article] 嚢胞性線維症に伴う膵障害2014

    • Author(s)
      石黒 洋、山本明子、中莖みゆき、藤木理代、近藤志保、洪 繁、柳元孝介、眞田幸弘、成瀬 達
    • Journal Title

      胆と膵

      Volume: 35 Pages: 1235-1238

    • Data Source
      KAKENHI-PROJECT-24591010
  • [Journal Article] 膵炎大全〜もう膵炎なんて怖くない〜膵炎における膵内分泌機能検査2014

    • Author(s)
      成瀬達、山本明子、石黒洋
    • Journal Title

      胆と膵

      Volume: 35 Pages: 1063-1067

    • Data Source
      KAKENHI-PROJECT-25460950
  • [Journal Article] 膵炎大全〜もう膵炎なんて怖くない〜嚢胞線維症に伴う膵障害2014

    • Author(s)
      石黒洋、山本明子、中莖みゆき、藤木理代、近藤志保、洪繁、柳元孝介、眞田幸弘、成瀬達
    • Journal Title

      胆と膵

      Volume: 35 Pages: 1235-1238

    • Data Source
      KAKENHI-PROJECT-25460950
  • [Journal Article] [新しい視点に立った膵内外分泌相関]膵の内外分泌相関 研究の源流から2014

    • Author(s)
      成瀬達、柴田時宗、鈴木厚、傍島裕司、山本明子、石黒洋
    • Journal Title

      胆と膵

      Volume: 35 Pages: 311-316

    • Data Source
      KAKENHI-PROJECT-25460950
  • [Journal Article] Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas2013

    • Author(s)
      Ko SB, Azuma S, Yokoyama Y, Yamamoto A, Kyokane K, Niida S, Ishiguro H, Ko MS
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 304 Issue: 12 Pages: 1103-1116

    • DOI

      10.1152/ajpgi.00299.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591010, KAKENHI-PROJECT-24591023
  • [Journal Article] Structure and function of the pancreas in the polycystic kidney rat2012

    • Author(s)
      Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H
    • Journal Title

      Pancreas

      Volume: (in press) Issue: 8 Pages: 1292-8

    • DOI

      10.1097/mpa.0b013e31824c12f9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-24591010
  • [Journal Article] Physiology and path physiology of bicarbonate secretion by pancreatic duct epithelium2012

    • Author(s)
      Ishiguro H, Yamamoto A, Nakakuki M, Yi L, Ishiguro M, Yamaguchi M, Kondo S, Mochimaru Y.
    • Journal Title

      Nagoya J Med Sci

      Volume: 74 Pages: 1-18

    • URL

      http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/01_Ishiguro.pdf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Journal Article] エタノールが膵導管細胞機能に及ぼす影響2012

    • Author(s)
      山本明子、濱田 広幸、石黒 洋
    • Journal Title

      膵臓

      Volume: 27 Pages: 121-131

    • NAID

      10030763956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Journal Article] Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.2012

    • Author(s)
      Song Y, Yamamoto A, Steward MC, Ko SB, Stewart AK , Soleimani M, Liu BC, Kondo T, Jin CX, Ishiguro H. Ishiguro H.
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: 303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.2012

    • Author(s)
      Y. Song
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: 303 Issue: 8 Pages: C815-C824

    • DOI

      10.1152/ajpcell.00151.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757, KAKENHI-PROJECT-24591010
  • [Journal Article] 汗の塩分濃度と膵臓の機能2012

    • Author(s)
      石黒 洋、山本明子、中莖みゆき、衣 蘭娟、石黒真理子、山口 誠、近藤志保、持丸由香
    • Journal Title

      総合保健体育科学

      Volume: 35 Pages: 9-15

    • NAID

      120005438195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Journal Article] Physiology and pathophysiology of bicarbonate secretion by pancreatic duct epithelium2012

    • Author(s)
      Ishiguro H, Yamamoto A, Nakakuki M, Yi L, Ishiguro M, Yamaguchi M, Kondo S, Mochimaru Y
    • Journal Title

      Nagoya J Med Sci

      Volume: 74 Pages: 1-18

    • NAID

      120003837113

    • URL

      http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/7412.html

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Journal Article] 導管細胞機能からみた膵炎再発の原因とその対策2012

    • Author(s)
      洪 繁、吉川俊之、山本明子、東 祥子、松浦俊博、京兼和宏、山田 理、石黒 洋
    • Journal Title

      胆と膵

      Volume: 33 Pages: 303-309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Journal Article] Physiology and pathophysiology of bicarbonate secretion by pancreatic duct epithelium.2012

    • Author(s)
      Ishiguro H, Yamamoto A, Nakakuki M, Yi L, Ishiguro M, Yamaguchi M, Kondo S, Mochimaru Y.
    • Journal Title

      Nagoya J Med Sci

      Volume: 74 Pages: 1-18

    • NAID

      120003837113

    • URL

      http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7412/01_Ishiguro.pdf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Molecular mechanisms of pancreatic stone formation in chronic pancreatitis.2012

    • Author(s)
      Ko SB, Azuma S, Yoshikawa T, Yamamoto A, Kyokane K, Ko MS, Ishiguro H.
    • Journal Title

      Front Physiol

      Volume: 3 Pages: 415-415

    • DOI

      10.3389/fphys.2012.00415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Journal Article] 【生活習慣と膵疾患】エタノールが膵導管細胞機能に及ぼす影響2012

    • Author(s)
      山本明子
    • Journal Title

      膵臓

      Volume: 27 Pages: 121-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Structure and function of the pancreas in the polycystic kidney rat.2012

    • Author(s)
      Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H
    • Journal Title

      Pancreas

      Volume: 41 Pages: 1292-1298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Physiology and pathophysiology of bicarbonate secretion by pancreatic duct epithelium.2012

    • Author(s)
      Ishiguro H, Yamamoto A, Nakakuki M, Yi L, Ishiguro M, Yamaguchi M, Kondo S, Mochimaru Y.
    • Journal Title

      Nagoya J Med Sci

      Volume: 74 Pages: 1-18

    • NAID

      120003837113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Journal Article] Intravenous fluid therapy successfully prevents renal injury by gemcitabine in patients with pancreatic cancer.2011

    • Author(s)
      Ko SB, Azuma S, Anzai N, Yamamoto A, Mizuno N, Kamimura K, Ishiguro H, Goto H.
    • Journal Title

      Pancreas in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Effects of CFTR gene silencing by siRNA or the luminal application of a CFTR activator on fluid secretion from guinea-pig pancreatic duct cells2011

    • Author(s)
      Ko SB, Yamamoto A, Azuma S, Song H, Kamimura K, Nakakuki M, Gray MA, Becq F, Ishiguro H, Goto H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 410 Issue: 4 Pages: 904-9

    • DOI

      10.1016/j.bbrc.2011.06.093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Journal Article] Intravenous fluid therapy successfully prevents renal injury by gemcitabine in patients with pancreatic cancer.2011

    • Author(s)
      Ko SB, Azuma S, Anzai N, Yamamoto A, Mizuno N, Kamimura K, Ishiguro H, Goto H.
    • Journal Title

      Pancreas

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Effects of CFTR gene silencing by siRNA or the luminal application of a CFTR activator on fluid secretion from guinea-pig pancreatic duct cells2011

    • Author(s)
      Ko SB, Yamamoto A, Azuma S, Song H, Kamimura K, Nakakuki M, Gray MA, Becq F, Ishiguro H, Goto H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 410 Pages: 904-9

    • URL

      http://dx.doi.org/10.1016/j.bbrc.2011.06.093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Journal Article] Intravenous fluid therapy successfully prevents renal injury by gemcitabine in patients with pancreatic cancer2011

    • Author(s)
      Ko SB, Azuma S, Yamamoto A, Iahiguro H, Goto H, et al.
    • Journal Title

      Pancreas

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Journal Article] Effects of CFTR gene silencing by siRNA or the luminal application of a CFTR activator on fluid secretion from guinea-pig pancreatic duct cells.2011

    • Author(s)
      Ko SB, Yamamoto A, Azuma S, Song H, Kamimura K, Nakakuki M, Gray MA, Becq F, Ishiguro H, Goto H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 410 Pages: 904-9

    • URL

      http://dx.doi.org/10.1016/j.bbrc.2011.06.093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Microperfusion and micropuncture analysis of ductal secretion2011

    • Author(s)
      Ishiguro H, Steward MC, Yamamoto A
    • Journal Title

      The Pancreapedia Exocrine Pancreas Knowledge Base 2011

    • DOI

      10.3998/panc.2011.16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-21590873, KAKENHI-PROJECT-22590757
  • [Journal Article] Effects of CFTR gene silencing by siRNA or the luminal application of a CFTR activator on fluid secretion from guinea-pig pancreatic duct cell2011

    • Author(s)
      SB.Ko, A.Yamamoto, S.Azuma, H.Song, K.Kamimura, M.Nakakuki, MA.Gray, H.Ishiguro, et.al
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 410 Pages: 904-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis.2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Naruse S, Yamao K, Muallem S, Goto H.
    • Journal Title

      Gastroenterology. 138(5)

      Pages: 1988-1996

    • NAID

      40017376759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Intravenous fluid therapy successfully prevents renal injury by gemcitab ine in patients with pancreatic cancer.2010

    • Author(s)
      Ko SB, Azuma S, Yamamoto A, Ishiguro H, Goto H, et. al.
    • Journal Title

      Pancreas

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Journal Article] Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Naruse S, Yamao K, Muallem S, Goto H
    • Journal Title

      Gastroenterology

      Volume: 138 Issue: 5 Pages: 1988-96

    • DOI

      10.1053/j.gastro.2010.01.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-21590873, KAKENHI-PROJECT-22590757
  • [Journal Article] Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis.2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, ishiguro H, Yamamoto A, Azuma S, Naruse S, Yamao K, Muallem S, Goto H.
    • Journal Title

      Gastroenterology.

      Volume: 138 Pages: 1988-1996

    • NAID

      40017376759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis.2010

    • Author(s)
      Ko SB, Mizuno N, Ishiguro H, Yamamoto A, Goto H, et al.
    • Journal Title

      Gastroenterology

      Volume: 138 Pages: 1988-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Journal Article] 【膵基礎研究の新しい潮流Bench to Bedをめざして】膵導管細胞機能とCFTRの役割2010

    • Author(s)
      石黒洋、洪繁、山本明子
    • Journal Title

      胆と膵

      Volume: 31 Pages: 527-533

    • Data Source
      KAKENHI-PROJECT-22590757
  • [Journal Article] Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis.2010

    • Author(s)
      Ko SB, Mizuno N, Ishiguro H, Yamamoto A, Goto H, et. al.
    • Journal Title

      Gastroenterology

      Volume: 138 Pages: 1988-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duct cells.2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SB, Goto H, Case RM, Kondo T, Yamamoto A.
    • Journal Title

      J Gen Physiol.

      Volume: 133 Pages: 315-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duct cells2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SB, Goto H, Case RM, Kondo T, Yamamoto A.
    • Journal Title

      J Gen Physiol 133(3)

      Pages: 315-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duct cells.2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SB, Goto H, Case RM, Kondo T, Yamamoto A.
    • Journal Title

      J Gen Physiol. 133

      Pages: 315-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Glucose transport in interlobular ducts isolated from rat pancreas.2009

    • Author(s)
      Futakuchi S, Ishiguro H, Naruse S, Ko SB, Fujiki K, Yamamoto A, Nakakuki M, Song Y, Steward MC, Kondo T, Goto H.
    • Journal Title

      J Med Invest 56

      Pages: 308-311

    • NAID

      130004822626

    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] High glucose inhibits HCO3-and fluid secretion in rat pancreatic ducts2009

    • Author(s)
      Futakuchi S, Ishiguro H, Naruse S, Ko SB, Fujiki K, Yamamoto A, Nakakuki M, Song Y, Steward MC, Kondo T, Goto H.
    • Journal Title

      Pflugers Arch

      Volume: 459 Issue: 1 Pages: 215-26

    • DOI

      10.1007/s00424-009-0731-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duct cells2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SB, Goto H, Case RM, Kondo T, Yamamoto A.
    • Journal Title

      J Gen Physiol 133(3)

      Pages: 315-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] Apical Cl-/HCO3- exchanger stoichiometry in the modeling of HCO3- transport by pancreatic duct epithelium.2009

    • Author(s)
      Yamaguchi M, Ishiguro H, Steward M, Sohma Y, Yamamoto A, Shimouchi A, Kondo T.
    • Journal Title

      J Med Invest.

      Volume: 56 Pages: 325-328

    • NAID

      130004822630

    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duct cells.2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SBH, Goto H, Case RM, Kondo T, Yamamoto A.
    • Journal Title

      J Gen Physiol 133

      Pages: 315-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] High glucose inhibits HCO_3 and fluid secretion in rat pancreatic ducts.2009

    • Author(s)
      Futakuchi S, Ishiguro H, Naruse S, Ko SB, Fujiki K, Yamamoto A, Nakakuki M, Song Y, Steward MC, Kondo T, Goto H.
    • Journal Title

      Pflugers Arch.

      Volume: 459 Pages: 215-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Aquaporin 1 water channel is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune pancreatitis.2009

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Naruse S, Yamao K, Muallem S, Goto H.
    • Journal Title

      J Med Invest

      Volume: 56 Pages: 318-321

    • NAID

      130004822628

    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Functional coupling of apical Cl-/HCO_3^- exchange with CFTR in stimulated HCO_3^- secretion by guinea pig interlobular pancreatic duct2009

    • Author(s)
      Stewart AK, Yamamoto A, Nakakuki M, Kondo T, Alper SL, Ishiguro H.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] Glucose transport in interlobular ducts isolated from rat pancreas.2009

    • Author(s)
      Futakuchi S, Ishiguro H, Naruse S, Ko SB, Fujiki K, Yamamoto A, Nakakuki M, Song Y, Steward MC, Kondo T, Goto H.
    • Journal Title

      J Med Invest

      Volume: 56 Pages: 308-311

    • NAID

      130004822626

    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] High glucose inhibits HCO3- and fluid secretion in rat pancreatic ducts.2009

    • Author(s)
      Futakuchi S, Ishiguro H, Naruse S, Ko SB, Fujiki K, Yamamoto A, Nakakuki M, Song Y, Steward MC, Kondo T, Goto H.
    • Journal Title

      Pflugers Arch. 459

      Pages: 215-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Effects of Slc26a6 deletion and CFTR inhibition on HCO3- secretion by mouse pancreatic duct.2009

    • Author(s)
      Song Y, Ishiguro H, Yamamoto A, Jin CX, Kondo T.
    • Journal Title

      J Med Invest.

      Volume: 56 Pages: 332-335

    • NAID

      130004822632

    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Apical Cl-/HCO3- exchanger stoichiometry in the modeling of HCO3- transport by pancreatic duct epithelium2009

    • Author(s)
      Yamaguchi M, Ishiguro H, Steward M, Sohma Y, Yamamoto A, Shimouchi A, Kondo T
    • Journal Title

      J. Med. Invest.

      Volume: 56 Issue: Supplement Pages: 325-328

    • DOI

      10.2152/jmi.56.325

    • NAID

      130004822630

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Journal Article] Aquaporin 1 water channel is overexpressedin the plasma membranes of pancreatic ducts in patients with autoimmune pancreatitis.2009

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Naruse S, Yamao K, Muallem S, Goto H.
    • Journal Title

      J Med Invest 56

      Pages: 318-321

    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Functional coupling of apical Cl-/HCO_3^- exchange with CFTR in stimulated HCO_3^- secretion by guinea pig interlobular pancreatic duct2009

    • Author(s)
      Stewart AK, Yamamoto A, Nakakuki M, Kondo T, Alper SL, Ishiguro H.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] Effects of Slc26a6 deletion and CFTR inhibition on HCO3- secretion by mouse pancreatic duct2009

    • Author(s)
      Song Y, Ishiguro H, Yamamoto A, Jin CX, Kondo T
    • Journal Title

      J. Med. Invest.

      Volume: 56 Issue: Supplement Pages: 332-335

    • DOI

      10.2152/jmi.56.332

    • NAID

      130004822632

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Journal Article] Functional coupling of apical Cl-/HCO3- exchange with CFTR in stimulated HCO3- secretion by guinea pig interlobular pancreatic duct.2009

    • Author(s)
      Stewart AK, Yamamoto A, Nakakuki M, Kondo T, Alper SL, Ishiguro H.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 296 Pages: 1307-1317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Journal Article] Functional coupling of apical Cl^-/HCO_3^-exchange with CFTR in stimulated HCO_3^-secretion by guinea pig interlobular pancreatic duct2009

    • Author(s)
      Stewart AK, Yamamoto A, Nakakuki M, Kondo T, Alper SL, Ishiguro H
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 296 Issue: 6 Pages: 1307-17

    • DOI

      10.1152/ajpgi.90697.2008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-21590873
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duct cells2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SB, Goto H, Case RM, Kondo T, Yamamoto A
    • Journal Title

      J Gen Physiol

      Volume: 133 Issue: 3 Pages: 315-26

    • DOI

      10.1085/jgp.200810122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-21590873
  • [Journal Article] CFTR functions as a bicarbonate channel in pancreatic duot cells.2009

    • Author(s)
      Ishiguro H, Steward MC, Naruse S, Ko SBH, Goto H, Case RM, Kondo T, Yamamoto A.
    • Journal Title

      J Gen Physiol 133

      Pages: 315-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] △Fマウスとslc26a6 nullマウスを用いた膵HCO_3^-分泌機構の解析2008

    • Author(s)
      石黒洋, 山本明子, 近藤孝晴
    • Journal Title

      膵臓 23

      Pages: 25-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] 汗中クロライド濃度の簡便な測定法の開発2008

    • Author(s)
      中莖みゆき, 石黒洋, 代田桂一, 山本明子, 洪繁, 後藤秀実, 藤木理代, 近藤孝晴, 遠藤彰, 成瀬達
    • Journal Title

      膵臓 23

      Pages: 486-493

    • NAID

      10024367756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] ΔFマウスとslc26a6 nullマウスを用いた2008

    • Author(s)
      石黒洋、山本明子、近藤孝晴
    • Journal Title

      膵HCO_3^-分泌機構の解析 23(1)

      Pages: 25-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] △Fマウスとslc26a6 nullマウスを用いた膵HC0_3^-分泌機構の解析2008

    • Author(s)
      石黒洋, 山本明子, 近藤孝晴
    • Journal Title

      膵臓 23

      Pages: 25-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] 汗中クロライド濃度の簡便な測定法の開発2008

    • Author(s)
      中莖みゆき、石黒洋、代田桂一、山本明子、洪繁、後藤秀実、藤木理代、近藤孝晴、遠藤彰、成瀬達
    • Journal Title

      膵臓 23(4)

      Pages: 5486-493

    • NAID

      10024367756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] 汗中クロライド濃度の簡便な測定法の開発2008

    • Author(s)
      中莖みゆき、石黒洋、代田桂一、山本明子、洪繁、後藤秀実、藤木理代、近藤孝晴、遠藤彰、成瀬達
    • Journal Title

      膵臓 23(4)

      Pages: 486-493

    • NAID

      10024367756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] ΔFマウスとslc26a6nullマウスを用いた2008

    • Author(s)
      石黒洋、山本明子、近藤孝晴
    • Journal Title

      膵HCO_3^-分泌機構の解析 23(1)

      Pages: 25-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] 汗中クロライド濃度の簡便な測定法の開発2008

    • Author(s)
      中莖みゆき, 石黒洋, 代田桂一, 山本明子, 洪繁, 後藤秀実, 藤木理代, 近藤孝晴, 遠藤彰, 成瀬達
    • Journal Title

      膵臓 23

      Pages: 486-493

    • NAID

      10024367756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] Acute tubulointerstitial nephritis associated with long-term gemcitabine therapy.2007

    • Author(s)
      Yamamoto A, Naruse S, Ito M, Ishiguro H, Ko SB, Yoshikawa T, Kondo T, Goto H
    • Journal Title

      Pancreas 34

      Pages: 378-379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] Effect of Slc26a6 deletion on apical Cl^-/HCO_3^- exchanger activity and Camp-stimulated bicarbonate secretion in pancreatic duct2007

    • Author(s)
      Ishiguro H, Namkung W, Yamamoto A, Wang Z, Worrell RT, Xu J, Lee MG, Soleimani M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 292(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Journal Article] Effect of Slc26a6 deletion on apical Cl^-/HCO^-_3-exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct2007

    • Author(s)
      Ishiguro H, Namkung W, Yamamoto A, Wang Z, Worrell RT, Xu J, Lee MG, Soleimani M
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 292

      Pages: 447-455

    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Effect of Slc26a6 deletion on apical Cl^-/HCO_<3>- exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct.2007

    • Author(s)
      Ishiguro H, Namkung W, Yamamoto A, Wang Z, Worrell RT, Xu J, Lee MG, Soleimani M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 292

      Pages: 447-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] Effect of S1c26a6 deletion on apical Cl^-/HCO_3^--exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct2007

    • Author(s)
      Ishiguro H, Namkung W, Yamamoto A, Wang Z, Worrell RT, Xu J, Lee MG, Soleimani M
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 292

      Pages: 447-455

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Effect of Slc26a6 deletion on apical Cl^-/HCO_3^-exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct2007

    • Author(s)
      Ishiguro H, Namkung W, Yamamoto A, Wang Z, Worrell RT, Xu J, Lee MG, Soleimani M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 292(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Journal Article] Relationship between skin acetone and blood beta-hydroxybutyrate concentration in diabetes2006

    • Author(s)
      Yamane N, Tsuda T, Nose K, Yamamoto A, Ishiguro H, Kondo T.
    • Journal Title

      Clin Chim Acta 365

      Pages: 325-329

    • Data Source
      KAKENHI-PROJECT-15590638
  • [Journal Article] 膵の重炭酸イオン分泌障害と膵嚢胞線維症/慢性膵炎2006

    • Author(s)
      石黒 洋, 成瀬 達, 近藤孝晴, 山本明子
    • Journal Title

      膵臓 21(1)

      Pages: 13-25

    • NAID

      10024365724

    • Data Source
      KAKENHI-PROJECT-15590638
  • [Journal Article] Relationship between skin acetone and blood beta-hydroxybutyrate concentration in diabetes2006

    • Author(s)
      Yamane N, Tsuda T, Nose K, Yamamoto A, Ishiguro H, Kondo T.
    • Journal Title

      Clin Chim Acta 365

      Pages: 325-329

    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Sweat chloride measurement with a highly sensitive electrode2006

    • Author(s)
      Naruse S, Ishiguro H, Shirota K, Nakakuki M, Yamamoto A, Kondo T
    • Journal Title

      Pancreas 33

      Pages: 100-100

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] 膵の重炭酸イオン分泌障害と膵嚢胞線維症/慢性膵炎2006

    • Author(s)
      石黒 洋, 成瀬 達, 近藤孝晴, 山本明子
    • Journal Title

      膵臓 21(1)

      Pages: 13-25

    • NAID

      10024365724

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Sweat chloride measurement with a highly sensitive electrode2006

    • Author(s)
      Naruse, S, Ishiguro H, Shirota K, Nakakuki M, Yamamoto A, Kondo T.
    • Journal Title

      Pancreas (in press)

    • Data Source
      KAKENHI-PROJECT-15590638
  • [Journal Article] Fecal pancreatic elastase : a reproducible marker for severe exocrine pancreatic insufficiency2006

    • Author(s)
      Naruse S, Ishiguro H, Ko SB, Yoshikawa T, Yamamoto T, Yamamoto A, Futakuchi S, Goto H, Saito Y, Takahashi S
    • Journal Title

      J Gastroenterol 41

      Pages: 901-908

    • NAID

      10020626404

    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Sweat chloride measurement with a highly sensitive electrode2006

    • Author(s)
      Naruse, S, Ishiguro H, Shirota K, Nakakuki M, Yamamoto A, Kondo T.
    • Journal Title

      Pancreas (in press)

    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Dual effects of n-alcohols on fluid secretion from guinea-pig pancreatic ducts2005

    • Author(s)
      Hamada H, Ishiguro H, Yamamoto A, Naruse, S, et al.
    • Journal Title

      Am J Physiol Cell Physiol 288

    • Data Source
      KAKENHI-PROJECT-15590638
  • [Journal Article] Dual effects of n-alcohols on fluid secretion from guinea-pig pancreatic ducts2005

    • Author(s)
      Hamada H, Ishiguro H, Yamamoto A, Naruse, S, et al.
    • Journal Title

      Am J Physiol Cell Physiol 288

    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Dual effects of n-alcohols on fluid secretion from guinea-pig pancreatic ducts2005

    • Author(s)
      Hamada H, Ishiguro H, Yamamoto A, Shimano-Futakuchi S, Ko SB, Yoshikawa T, Goto H, Kitagawa M, Hayakawa T, Seo Y, Naruse S
    • Journal Title

      Am J Physiol Cell Physiol 288

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590164
  • [Journal Article] Structure and function of the pancreas in the polycystic kidney rat

    • Author(s)
      Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H.
    • Journal Title

      Pancreas

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Presentation] 中鎖脂肪酸とカルニチンはモルモット単離小葉間膵管の水分泌を促進する2023

    • Author(s)
      樋口万佑子,山本明子,谷口いつか,野村奈央,丹羽永理奈,中茎みゆき,石黒 洋
    • Organizer
      第100回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-22K08075
  • [Presentation] ワークショップ6「臨床応用を見据えた膵臓基礎研究」モルモット単離小葉間膵管の膵液分泌に中鎖脂肪酸がおよぼす影響と長鎖脂肪酸との比較2023

    • Author(s)
      樋口万佑子,山本明子,中莖みゆき,谷口いつか,野村奈央,丹羽永理奈,山口誠,石黒 洋
    • Organizer
      第54回日本膵臓学会大会(福岡)
    • Data Source
      KAKENHI-PROJECT-22K08075
  • [Presentation] Effects of GLP-1, GIP, and glucagon on pancreatic fluid secretion in guinea-pig interlobular pancreatic duct.2022

    • Author(s)
      Higuchi M, Yamamoto A, Taniguchi I, Nomura N, Niwa E, Nakakuki M, Yamaguchi M, Liu L, Ishiguro H
    • Organizer
      第26回国際膵臓学会/第53回日本膵臓学会大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Presentation] わが国のCF患者のCFTR variantの特徴 ワークショップ「胆膵疾患の遺伝子解析による病態解明・臨床展開」2022

    • Author(s)
      中莖みゆき、山本明子、石黒 洋
    • Organizer
      第108回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Presentation] Effects of incretinGLP-1, GIP, and glucagon on fluidpancreatic secretion in guinea-pig interlobular pancreatic duct2022

    • Author(s)
      M. Higuchi, A. Yamamoto, I. Taniguchi, N. Nomura, E.Niwa, M.Nakakuki, M.Yamaguchi, L. Liu, H. Ishiguro
    • Organizer
      第26回国際膵臓学会/第53回日本膵臓学会大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08075
  • [Presentation] Roles of zinc in fluid secretion from pancreatic duct cells.2022

    • Author(s)
      Nomura N, Yamamoto A, Nakakuki M, Mochimaru Y, Taniguchi I, Liu L, Kozawa Y, Higuchi M, Niwa E, Ishiguro H
    • Organizer
      第26回国際膵臓学会/第53回日本膵臓学会大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Presentation] パネルディスカッション「膵内外分泌機能障害の診断と治療」日本の嚢胞性線維症患者のCFTRバリアントと膵外分泌機能2021

    • Author(s)
      山本明子、中莖みゆき、成瀬 達、小澤祐加、藤木理代、近藤志保、竹山宜典、石黒 洋
    • Organizer
      第52回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Presentation] ワークショップ7「膵炎研究の最前線:基礎から臨床へ」マウス単離小葉間膵管の水分泌に亜鉛欠乏がおよぼす影響2021

    • Author(s)
      山本明子
    • Organizer
      第51回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-19K08441
  • [Presentation] 嚢胞性線維症患者の腸内細菌叢解析2021

    • Author(s)
      福安智哉、藤木理代、中村浩平、鈴木 徹、成瀬 達、山本明子、近藤志保、中莖みゆき、小澤祐加、石黒 洋
    • Organizer
      第52回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-20K08285
  • [Presentation] CFTR function and CFTR mutations of cystic fibrosis in Japan2019

    • Author(s)
      Kozawa Y, Yamamoto A, Nakakuki M, Fujiki K, Kondo S, Taniguchi I, Naruse S, Ishiguro H
    • Organizer
      9th Congress of Federation of the Asian and Oceanian Physiological Societies 第96回日本生理学会大会 合同会議
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] 単離小葉間膵管の水分泌に亜鉛とアルブミンが及ぼす影響と亜鉛トランスポータの発現2018

    • Author(s)
      野村 奈央、 山本 明子、中莖 みゆき、石黒 洋
    • Organizer
      第49回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] 嚢胞性線維症の重症度判定基準改訂の提案2018

    • Author(s)
      石黒洋、山本明子、中莖みゆき、藤木理代、近藤志保、成瀬 達、竹山宜典
    • Organizer
      第49回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] 嚢胞性線維症の重症度判定基準改訂の提案2018

    • Author(s)
      石黒 洋、 山本 明子、 中莖 みゆき、藤木 理代、近藤 志保、 成瀬 達、竹山 宜典
    • Organizer
      第49回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] Clinical characteristics, prognosis, and CFTR mutations of cystic fibrosis in Japan2018

    • Author(s)
      Ishiguro H, Yamamoto A, Fujiki K, Nakakuki M, Taniguchi I, Kozawa Y, Sohma Y, Naruse S, Takeyama Y
    • Organizer
      49th Annual Meeting of American Pancreatic Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] 嚢胞性線維症患者の栄養状態と栄養ケア2018

    • Author(s)
      藤木理代、石黒 洋、山本明子、中莖みゆき、近藤志保、竹山宜典、成瀬 達
    • Organizer
      第49回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] 嚢胞性線維症患者の栄養状態と栄養ケア2018

    • Author(s)
      藤木 理代、石黒 洋、 山本 明子、中莖 みゆき、近藤 志保、竹山 宜典、成瀬 達
    • Organizer
      第49回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] NH4+およびAcO-パルスによる膵導管細胞内pH 変化のコンピュータ・シミュレーション2018

    • Author(s)
      石黒 洋、山口 誠、スチュワード マーチン、山本 明子
    • Organizer
      第 95 回日本生理学会大会 (高松)
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] Clinical characteristics, prognosis, and CFTR mutations of cystic fibrosis in Japan2018

    • Author(s)
      H. Ishiguro, A. Yamamoto, K. Fujiki, M. Nakakuki, I. Taniguchi, Y. Kozawa, Y. Sohma, S. Naruse, Y. Takeyama
    • Organizer
      49th Annual Meeting of American Pancreatic Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] 「ワークショップ14:基礎研究から紐解く膵・胆道の恒常性とその破綻」 cystic fibrosisマウスの単離膵管におけるH+/HCO3-輸送2018

    • Author(s)
      山本 明子、 谷口 いつか、石黒 洋
    • Organizer
      第104回日本日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] モルモット膵導管細胞の液体分泌に及ぼすカフェインとエタノールの影響2017

    • Author(s)
      持丸由香、山本明子、中莖みゆき、山口 誠、谷口いつか、石黒 洋
    • Organizer
      第48回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] モルモット単離小葉間膵管の水分泌にアルブミンと亜鉛が及ぼす影響2017

    • Author(s)
      山本明子、中莖みゆき、石黒 洋
    • Organizer
      第59回日本消化器病学 会大会 DDW-Japan2017 (福岡)
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] 多発性嚢胞腎症ラットの膵管内primary ciliaの形態と機能2017

    • Author(s)
      衣 蘭娟、山本明子、長尾枝澄香、成瀬 達、石黒 洋
    • Organizer
      第48回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] モルモット単離小葉間膵管の水分泌にアルブミンと亜鉛が及ぼす影響2017

    • Author(s)
      山本明子、中莖みゆき、石黒 洋
    • Organizer
      第59回日本消化器病学会大会DDW-Japan2017
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] 便中膵エラスターゼ迅速試験による嚢胞性線維症の膵外分泌不全の診断2017

    • Author(s)
      成瀬 達、近藤志保、藤木理代、中莖みゆき、山本明子、石黒 洋
    • Organizer
      第48回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] ”ワークショップ”アルコール性臓器障害発症の分子機序と治療への応用 膵導管細胞機能に対するアルコールとカフェインの影響2017

    • Author(s)
      石黒 洋、藤木理代、山本明子
    • Organizer
      第103回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] Role of CFTR dysfunction in the pathogenesis of chronic pancreatitis2016

    • Author(s)
      Akiko Yamamoto, Shiho Kondo, Kotoyo Fujiki, Miyuki Nakakuki,Yuka Kondo,Itsuka Taniguchi, Yuka Usami, Satoru Naruse, Hiroshi Ishiguro
    • Organizer
      The 47th annual meeting of the Japan Pancreas Society, The 20th meeting of the International Association of Pancreatology, The 6th meeting of the Asian Oceanic Pancreatic Association
    • Place of Presentation
      仙台
    • Year and Date
      2016-08-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] Exocrine pancreatic function in Japanese patients with cystic fibrosis2016

    • Author(s)
      Satoru Naruse, Shiho Kondo, Kotoyo Fujiki, Akiko Yamamoto, Miyuki Nakakuki, Toru Shimosegawa, Yoshifumi Takeyama, Hiroshi Ishiguro
    • Organizer
      The 47th annual meeting of the Japan Pancreas Society, The 20th meeting of the International Association of Pancreatology, The 6th meeting of the Asian Oceanic Pancreatic Association
    • Place of Presentation
      仙台
    • Year and Date
      2016-08-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] Nationwide epidemiological survey of cystic fibrosis in Japan2016

    • Author(s)
      Yuka Usami, Akiko Yamamoto,Miyuki Nakakuki, Kotoyo Fujiki, Satoru Naruse Hiroshi, Hiroshi Ishiguro
    • Organizer
      The 47th annual meeting of the Japan Pancreas Society, The 20th meeting of the International Association of Pancreatology, The 6th meeting of the Asian Oceanic Pancreatic Association
    • Place of Presentation
      仙台
    • Year and Date
      2016-08-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] 膵導管細胞の水分泌に亜鉛が及ぼす影響2016

    • Author(s)
      山本明子、中莖みゆき、石黒 洋
    • Organizer
      第58回日本消化器病学 会大会 DDW-Japan2016
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-16K09393
  • [Presentation] Combination of L1156F and M470V in CFTR Gene Associated with Alcoholic Chronic Pancreatitis in Japanese2016

    • Author(s)
      Shiho Kondo, Kotoyo Fujiki, Shigeru B. H. Ko, Akiko Yamamoto, Miyuki Nakakuki, Yasutomo Ito, Motoji Kitagawa, Satoru Naruse, and Hiroshi Ishiguro
    • Organizer
      The 47th Annual Meeting of the American Pancreatic Association
    • Place of Presentation
      Boston
    • Year and Date
      2016-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09392
  • [Presentation] CFTR遺伝子の転写活性にpromoter部の遺伝子多型が及ぼす影響2015

    • Author(s)
      中瀬 敦, 中莖 みゆき, 藤木 理代, 山本 明子, 成瀬 達, 石黒 洋
    • Organizer
      第46回日本膵臓学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-19
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] ミニシンポジウム「膵疾患の分子病態 -Basics and Applications-」 CFTRの機能障害に起因する膵疾患の分子病態2015

    • Author(s)
      山本 明子, 近藤 志保, 藤木 理代, 中莖 みゆき, 洪 繁, 成瀬 達, 石黒 洋
    • Organizer
      第46回日本膵臓学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-19
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] 嚢胞性線維症の 1 症例2014

    • Author(s)
      山本 明子、中莖 みゆき、伊藤 治、石黒 洋、成瀬 達
    • Organizer
      日本消化器病学会東海支部第121回例会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] 腸内環境が脂肪酸のセンシングメカニズムに及ぼす影響2013

    • Author(s)
      山本 明子, 中莖 みゆき,山口 誠, 近藤 志保, 山本 明子, 洪 繁, 北川 元二, 石黒 洋
    • Organizer
      生理研研究会
    • Place of Presentation
      岡崎市
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] Role of channel and transporters in pancreatic secretion2013

    • Author(s)
      Ishiguro H, Yamamoto A
    • Organizer
      IAP (International Association of Pancreatology) & KPBA (Korean Pancreatobiliary Association)合同研究集会
    • Place of Presentation
      Seoul
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Presentation] トピックスセッション1「膵疾患の克服を目指した基礎研究」 膵導管細胞管腔膜のカルシウム輸送とメカノセンサー機能2013

    • Author(s)
      石黒真理子、山本明子、長尾枝澄香、成瀬 達、石黒 洋
    • Organizer
      第44回日本膵臓学会大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24591010
  • [Presentation] 膵疾患の遺伝的背景を探る パネルディスカッション1 「わが国の嚢胞性線維症におけるCFTR遺伝子変異」2011

    • Author(s)
      中莖みゆき、山本明子、藤木理代、石黒洋、成瀬達
    • Organizer
      第42回日本膵臓学会大会
    • Place of Presentation
      青森
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Presentation] 膵疾患の遺伝的背景を探る パネルディスカッション1 「性膵炎におけるCFTR遺伝子の関与」2011

    • Author(s)
      藤木理代、石黒洋、中莖みゆき、近藤志保、山本明子、洪繁、北川元二、成瀬達
    • Organizer
      第42回日本膵臓学会大会
    • Place of Presentation
      青森
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Presentation] Role of basolateral Cl^-HCO_3^-exchange in HCO_3^-secretion in a computational model of electrolyte transport by pancreatic duct epithelium2011

    • Author(s)
      Yamaguchi M, Steward MC, Yamamoto A, Sohma Y, Ko SB, Kondo T, Ishiguro H
    • Organizer
      The Physiological Society
    • Place of Presentation
      Oxford
    • Year and Date
      2011-07-13
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Presentation] Corticosteroid correct aberrant cystic fibrosis transmembrane conductance regulator localization in the duct and regenerate acinar cells in autoimmune pancreatitis.2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Nause S, Yamao K, Muallem S, Goto H.
    • Organizer
      European Pancreatic Club meeting at Stockholm
    • Place of Presentation
      Sweden
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Molecular and cellular regulation of pancreatic duct function2010

    • Author(s)
      Ishiguro H, Ko SB, Yamamoto A
    • Organizer
      Symposium "Chronic Pancreatitis : Pathogenesis to Treatment", Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
    • Place of Presentation
      Fukuoka
    • Year and Date
      2010-07-12
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Presentation] Corticosteroid correct aberrant cystic fibrosis transmembrane conductance regulator localization in the duct and regenerate acinar cells in autoimmune pancreatitis2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Nause S, Yamao K, Muallem S, Goto H.
    • Organizer
      European Pancreatic Club meeting
    • Place of Presentation
      ストックホルム、スウェーデン
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Fluid secretion from the pancreatic duct in PCK rats2010

    • Author(s)
      Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Presentation] 膵液のアルカリ化障害におけるNa+-H+交換輸送体の役割パネルディスカッション「膵炎の基礎と臨床」2010

    • Author(s)
      山本明子
    • Organizer
      第52回日本消化器病学会大会DDW-Japan 2010
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Presentation] Fluid secretion from the pancreatic duct in PCK rats2010

    • Author(s)
      Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S, Wei M, Kondo T, Naruse S
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
    • Place of Presentation
      Fukuoka
    • Year and Date
      2010-07-13
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Presentation] 膵導管細胞において膵石形成に関わるカルシウム輸送体の検討2010

    • Author(s)
      石黒真理子、石黒洋、山本明子、藤木理代、北川元二、近藤孝晴
    • Place of Presentation
      第64回日本栄養・食糧学会大会(徳島)
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Presentation] Corticosteroid correct aberrant cystic fibrosis transmembrane conductance regulator localization in the duct and regenerate acinar cells in autoimmune pancreatitis.2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Nause S, Yamao K, Muallem S, Goto H.
    • Organizer
      International Association of Pancreatology at Fukuoka
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Corticosteroid correct aberrant cystic fibrosis transmembrane conductance regulator localization in the duct and regenerate acinar cells in autoimmune pancreatitis2010

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Yoshikawa T, Ishiguro H, Yamamoto A, Azuma S, Nause S, Yamao K, Muallem S, Goto H
    • Organizer
      International Association of Pancreatology
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2010-07-11
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] 膵疾患の遺伝的背景を探る パネルディスカッション1 膵液のアルカリ化障害におけるNa+-H+交換輸送体の役割 パネルディスカッション「膵炎の基礎と臨床」2010

    • Author(s)
      山本明子、石黒洋
    • Organizer
      第52回日本消化器病学会大会 DDW-Japan
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Presentation] Molecular and cellular regulation of pancreatic duct function2010

    • Author(s)
      Ishiguro H, Ko SB, Yamamoto A.
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Presentation] Symposium"Chronic Pancreatitis: Pathogenesis to Treatment"Molecular and cellular regulation of pancreatic duct function2010

    • Author(s)
      Ishiguro H, Ko SBH, Yamamoto A
    • Organizer
      Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
    • Place of Presentation
      Fukuoka
    • Year and Date
      2010-07-13
    • Data Source
      KAKENHI-PROJECT-22590757
  • [Presentation] 膵癌治療薬ゲムシタビンによる高尿酸血症副作用における尿酸トランスポーターURAT1の役割2009

    • Author(s)
      洪繁、東祥子、山本明子、石黒洋、後藤秀実
    • Organizer
      第4回トランスポーター研究会
    • Place of Presentation
      東京大学
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Aquaporin Water channel protein is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune chronic pancreatitis.2009

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Ishiguro H, Azuma S, Yoshikawa T, Yamamoto A, Naruse S, Yamao K, Muallem S, Goto H
    • Organizer
      International Symposium in Exocrine Secretion
    • Place of Presentation
      徳島大学
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] 塩酸ゲムシタビン腎症予防における輸液療法の有用性2009

    • Author(s)
      洪繁、石黒洋、山本明子、東祥子、後藤秀実
    • Organizer
      日本消化器病学会東海支部第111回例会シンポジウム「肝胆膵悪性腫瘍に対する診断と治療の進歩」
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] 膵導管細胞におけるカルシウム輸送体の発現と局在の検討2009

    • Author(s)
      石黒真理子、石黒洋、山本明子、藤木理代、北川元二、近藤孝晴
    • Organizer
      第40回日本膵臓学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590873
  • [Presentation] Aquaporin Water channel protein is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune chronic pancreatitis.2009

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Ishiguro H, Azuma S, Yoshikawa T, Yamamoto A, Naruse S, Yamao K, Muallem S, Goto H.
    • Organizer
      Symposium 3, Speaker Aquaporin and Ion channel/Transporter : Physiology and Disease : Part II International Symposium in Exocrine Secretion at Tokushima, 2009
    • Place of Presentation
      Tokushima University, Japan
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Interaction between CFTR Cl^-channel and SLC26a6 anion exchangers2009

    • Author(s)
      Ishiguro H, Song Y, Kondo T, Yamamoto A
    • Organizer
      The 41st meeting of The European Pancreatic Club
    • Place of Presentation
      Szeged
    • Year and Date
      2009-07-02
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Presentation] 塩酸ゲムシタビン腎症予防における輸液療法の有用性2009

    • Author(s)
      洪繁、石黒洋、山本明子、東祥子、後藤秀実
    • Organizer
      日本消化器病学会東海支部第111回例会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] 膵導管細胞管腔膜のNa^+-H^+exchangerによる膵液酸性化と膵障害2009

    • Author(s)
      山本明子、石黒洋、近藤孝晴
    • Organizer
      シンポジウム「慢性膵炎の基礎研究における最近の進歩-新しい診断と治療法の開発に向けての展望-」第40回日本膵臓学会大会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-31
    • Data Source
      KAKENHI-PROJECT-21590332
  • [Presentation] 膵癌治療薬ゲムシタビンによる高尿酸血症副作用における尿酸トランスポーターURAT1の役割2009

    • Author(s)
      洪繁、東祥子、山本明子、石黒洋、後藤秀実
    • Organizer
      第4回トランスポーター研究会
    • Place of Presentation
      シンポジウムII、東京大学
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Aquaporin Water channel protein is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune chronic pancreatitis.2008

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Ishiguro H, Yoshikawa T, Yamamoto A, Naruse S, Muallem S, Yamao K, Goto H.
    • Organizer
      Autoimmune pancreatitis Summit AIP 2008
    • Place of Presentation
      Seoul, South Korea
    • Year and Date
      2008-07-04
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] The genetic background of CFTR and ALDH2 is related to alcoholic chronic pancreat it is in Japanese.2008

    • Author(s)
      Fujiki K, Ishiguro H, Nakakuki M, Yamamoto A, Kitagawa M, Kondo T, Naruse S.
    • Organizer
      16th United European Gastroenterology Week
    • Place of Presentation
      ウィーン
    • Year and Date
      2008-10-22
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] Aquaporin Water channel protein is overexpressed in the plasma membranes of pancreatic ducts in patients with autoimmune chronic pancreatitis.2008

    • Author(s)
      Ko SB, Mizuno N, Yatabe Y, Ishiguro H, Yoshikawa T, Yamamoto A, Naruse S, Muallem S, Yamao K, Goto H
    • Organizer
      The international Pancretic Research Forum
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2008-03-22
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Regulatory interaction of the apical Na^+-H^+ exchange in HCO_3^-secretion in mouse pancreatic duct cells2008

    • Author(s)
      Yamamoto A, Ishiguro H, Kondo T.
    • Organizer
      16th United European Gastroenterology Week
    • Place of Presentation
      Vienna
    • Year and Date
      2008-10-22
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Presentation] The genetic background of CFTR and ALDH2 is related to alcoholic chronic pancreatitis in Japanese2008

    • Author(s)
      Fujiki K, Ishiguro H, Nakakuki M, Yamamoto A, Kitagawa M, Kondo T, Naruse S.
    • Organizer
      16th United European Gastroenterology Week
    • Place of Presentation
      Vienna
    • Year and Date
      2008-10-22
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] CFTR-SLC26輸送体複合体のイオン輸送機能における低分子量G蛋白質の役割文部省科学研究費補助金特定領域生体膜トランスポートソームの分子機構と生理機能2008

    • Author(s)
      洪繁、石黒洋、山本明子、有村奈利子、相馬義郎、後藤秀実
    • Organizer
      平成20年度第一回班会議
    • Place of Presentation
      淡路夢舞台国際会議場、兵庫県淡路市
    • Year and Date
      2008-09-26
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] slc26a6ノックアウトマウスから単離した小葉間膵管の重炭酸イオン輸送2008

    • Author(s)
      石黒洋、山本明子、近藤孝晴
    • Organizer
      第85回日本生理学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-25
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] slc26a6ノックアウトマウスから単離した小葉間膵管の重炭酸イオン輸送2008

    • Author(s)
      石黒洋、山本明子、近藤孝晴
    • Organizer
      第85回日本生理学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-03-25
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Presentation] アルコール性慢性膵炎患者のCFTRおよびALDH2遺伝子多型の解析(要望演題)2008

    • Author(s)
      藤木理代、石黒 洋、中莖みゆき、山本明子、北川元二、近藤孝晴、成瀬達
    • Organizer
      第39回日本膵臓学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2008-07-30
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] Regulatory interaction of the apical Na^+-H^+ exchange in HCO_3- secretion in mouse pancreatic duct cells.2008

    • Author(s)
      Yamamoto A, Ishiguro H, Naruse S, Kondo T.
    • Organizer
      16th United European Gastroenterology Week
    • Place of Presentation
      ウィーン
    • Year and Date
      2008-10-22
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Presentation] Regulatory interaction of the apical Na+-H+ exchange in HCO_3^- secretion in mouse pancreatic duct cells.2008

    • Author(s)
      Yamamoto A, Ishiguro H, Kondo T.
    • Organizer
      16th United European Gastroenterology Week
    • Place of Presentation
      Vienna
    • Year and Date
      2008-10-22
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] RNA干渉法を用いたモルモットCFTR機能の解析2008

    • Author(s)
      洪繁、山本明子、宋海珍、石黒洋、後藤秀実
    • Organizer
      第3回トランスポーター研究会
    • Place of Presentation
      京都大学、薬学部
    • Data Source
      KAKENHI-PROJECT-20590807
  • [Presentation] Interaction between cystic fibrosis transmembrane conductance regulator and Na+-H+ exchange in mouse pancreatic ducts2007

    • Author(s)
      Yamamoto A, Ishiguro H, Ko SB, Naruse S, Kondo T.
    • Organizer
      Asian Pacific Digestive Week 2007
    • Place of Presentation
      Kobe
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] Interaction between cystic fibrosis transmembrane conductance regulator and Na^+-H^+ exchange in mouse pancreatic ducts2007

    • Author(s)
      Yamamoto A, Ishiguro H, Ko SB, Naruse S, Kondo T.
    • Organizer
      Asian Pacific Digestive Week 2007
    • Place of Presentation
      Kobe
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Presentation] ΔFマウスおよびSlc26a6ノックアウトマウスから単離した小葉間膵管の重炭酸イオン輸送ワークショップ「膵研究モデルの作成、選択、適用」2007

    • Author(s)
      石黒洋、山本明子、近藤孝晴
    • Organizer
      第38回日本膵臓学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-19590758
  • [Presentation] ΔFマウスおよびSlc26a6ノックアウトマウスから単離した小葉間膵管の重炭酸イオン輸送 ワークショップ「膵研究モデルの作成、選択、適用」2007

    • Author(s)
      石黒洋、山本明子、近藤孝晴
    • Organizer
      第38回日本膵臓学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-19590303
  • [Presentation] 膵嚢胞線維症マウスから単離した小葉間膵管の水輸送

    • Author(s)
      山本明子、中莖みゆき、石黒洋
    • Organizer
      第55回日本消化器病学会大会&#8199;DDW-Japan2014
    • Place of Presentation
      神戸
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese

    • Author(s)
      Shiho Kondo, Kotoyo Fujiki, Shigeru BH Ko, Akiko Yamamoto, Miyuki Nakakuki, Yasutomo Ito, Motoji Kitagawa, Satoru Naruse, Hiroshi Ishiguro
    • Organizer
      45th Anniversary Meeting of American Pancreatic Association/Japan Pancreas Society
    • Place of Presentation
      Hawaii
    • Year and Date
      2014-11-05 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] 便中エラスターゼによる膵嚢胞線維症(CF)の膵外分泌機能の評価

    • Author(s)
      成瀬達、石黒洋、山本明子 、柴田時宗、伊藤治、濱田広幸、 木村純、北川元二、下瀬川徹
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-23 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] Incidence and exocrine pancreatic function of cystic fibrosis in Japan

    • Author(s)
      Satoru Naruse, Hiroshi Ishiguro, Akiko Yamamoto, Shiho Kondo, Miyuki Nakakuki, Mikiko
    • Organizer
      45th Anniversary Meeting of American Pancreatic Association/Japan Pancreas Society
    • Place of Presentation
      Hawaii
    • Year and Date
      2014-11-05 – 2014-11-08
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] 小腸上皮におけるグルコース吸収の数理モデル

    • Author(s)
      山口誠、山本明子、谷口いつか、石黒洋
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] 嚢胞線維症マウスから単離した小葉間膵管におけるHCO3-輸送

    • Author(s)
      谷口いつか、山本明子、山口誠、石黒洋
    • Organizer
      第92回日本生理学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-25460950
  • [Presentation] カフェインがモルモット単離小葉間膵管

    • Author(s)
      持丸由香、 山本明子、中莖みゆき、 山口誠、近藤志保、谷口いつか、石黒洋
    • Organizer
      第45回日本膵臓学会大会
    • Place of Presentation
      北九州
    • Year and Date
      2014-07-11 – 2014-07-12
    • Data Source
      KAKENHI-PROJECT-25460950
  • 1.  ISHIGURO Hiroshi (90303651)
    # of Collaborated Projects: 18 results
    # of Collaborated Products: 180 results
  • 2.  KO Shigeru (90402578)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 53 results
  • 3.  KONDO Takaharu (20135388)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 35 results
  • 4.  SOHMA YOSHIRO (60268183)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 5.  GOTO Hidemi (10215501)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 26 results
  • 6.  NAGAO Shizuko (20183527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 7.  NAKAKUKI MIyuki (30578729)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 8.  NARUSE Satoru (50180550)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 9.  KUME Hiroaki (50303631)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  FUJIKI Kotoyo (50454450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 11.  MIZUNO Nobumasa (80399592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 12.  FURUYA Sonoko (20096952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KO Minoru (50631199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAKATAKE Yuhki (20415251)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NIIDA Shunpei (10137630)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MATSUURA Toshihiro (80501626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  有村 奈利子 (20420375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  小川 真一郎 (30419353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  川嶋 啓揮 (20378045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山口 淳平 (00566987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  石川 卓哉 (00792649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  飯田 忠 (30878319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  水谷 泰之 (50831393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  AKIBA Yasutada
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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