Ebihara Akio 海老原章郎

… Alternative Names

EBIHARA Akio 海老原章郎

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Researcher Number	60415099
Other IDs	https://orcid.org/0000-0002-1763-9084
Affiliation (Current)	2025: 岐阜大学, 応用生物科学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 岐阜大学, 応用生物科学部, 教授 2012 – 2015: 岐阜大学, 応用生物科学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Applied health science / Applied biochemistry Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
Keywords	Principal Investigator プロレニン / SDGs / 臨床現場即時検査法 / 糖尿病 / バイオマーカー / 糖尿病合併症 / 血管障害 / 予防医療 / プロレニン、 / 抗体 … More / 酵素化学 / 血圧調節 / レニン・アンジオテンシン系 / レニン / プロ酵素 … More Except Principal Investigator RPR / FP / IIAEK / 脂質 / ペプチド Less

Fundamental research on elucidation of novel biological acceptance mechanisms and innovative applications of food-derived lipid metabolism improving peptides
- Principal Investigator
  
  長岡利
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Gifu University
Simultaneous on-site measurement of multi-markers associated with microvascular complications and its applications to prediction of diabetic complicationsPrincipal Investigator
- Principal Investigator
  
  Ebihara Akio
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gifu University
Understanding of the pathobiochemical significance of prorenin, an early marker of diabetic complications: collaborative work between India, Bangladesh and JapanPrincipal Investigator
- Principal Investigator
  
  Ebihara Akio
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Gifu University
Development of point-of-care testing for an early maker of diabetes complicationsPrincipal Investigator
- Principal Investigator
  
  Ebihara Akio
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Gifu University
Investigation of the molecular mechanism underlining inactivation states of proenzyme and its application for drug designPrincipal Investigator
- Principal Investigator
  
  EBIHARA Akio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied biochemistry
- Research Institution
  Gifu University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Mutational landscape of mitochondrial cytochrome b and its flanking tRNA genes associated with increased mitochondrial DNA copy number and disease risk in children with autism2024
- Author(s)
  Adiba Maisha、Rahman Molie、Akter Hosneara、Rahman Md Mizanur、Uddin Mohammed、Ebihara Akio、Nabi A.H.M.Nurun
- Journal Title
  
  Gene Reports
  
  Volume: 35 Pages: 101895-101895
- DOI
  10.1016/j.genrep.2024.101895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Production of recombinant His-tagged triple-FLAG peptide in Brevibacillus choshinensis and its utilization as an easy-to-remove affinity peptide2023
- Author(s)
  Sugihara Daiki、Ono Fuka、Sugino Motoki、Suzuki Hiromi、Endo Noriko、Shimada Atsuhiro、Ebihara Akio
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 87 Issue: 9 Pages: 1029-1035
- DOI
  10.1093/bbb/zbad079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Impacts of SARS-CoV-2 on diabetes mellitus: A pre and post pandemic evaluation2023
- Author(s)
  Nabi A H M Nurun、Ebihara Akio、Shekhar Hossain Uddin
- Journal Title
  
  World Journal of Virology
  
  Volume: 12 Issue: 3 Pages: 151-171
- DOI
  10.5501/wjv.v12.i3.151
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis2022
- Author(s)
  Ebihara Akio、Sugihara Daiki、Matsuyama Makoto、Suzuki-Nakagawa Chiharu、Nabi A. H. M. Nurun、Nakagawa Tsutomu、Nishiyama Akira、Suzuki Fumiaki
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 4 Pages: 959-971
- DOI
  10.1038/s41440-022-01094-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Boosting Auto-Induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives2021
- Author(s)
  Tahara Nariyasu、Tachibana Itaru、Takeo Kazuyo、Yamashita Shinji、Shimada Atsuhiro、Hashimoto Misuzu、Ohno Satoshi、Yokogawa Takashi、Nakagawa Tsutomu、Suzuki Fumiaki、Ebihara Akio
- Journal Title
  
  Protein & Peptide Letters
  
  Volume: 28 Issue: 10 Pages: 1180-1190
- DOI
  10.2174/0929866528666210805120715
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05692, KAKENHI-PROJECT-18KK0273
[Journal Article] Non-coding Single Nucleotide Variants of Renin and the (Pro)renin Receptor are Associated with Polygenic Diseases in a Bangladeshi Population2021
- Author(s)
  Akther Jobaida, Das Ashish, Rahman Md Arifur, Saha Sajoy Kanti, Hosen Md Ismail, Ebihara Akio, Nakagawa Tsutomu, Suzuki Fumiaki, Nabi A. H. M. Nurun
- Journal Title
  
  Biochemical Genetics
  
  Volume: － Issue: 5 Pages: 1116-1145
- DOI
  10.1007/s10528-021-10049-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Diabetes and Renin-Angiotensin-Aldosterone System: Pathophysiology and Genetics2021
- Author(s)
  Nurun Nabi A.H.M.、Ebihara Akio
- Journal Title
  
  IntechOpen (Book: ISBN 978-1-83968-287-2)
  
  Volume: - Pages: 21-51
- DOI
  10.5772/intechopen.97518
- ISBN
  9781839682865, 9781839682872
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Establishing a novel assay system for measuring renin concentration using cost effective recombinant ovine angiotensinogen2019
- Author(s)
  Akther Jobaida、Nabi A.H.M. Nurun、Ohno Satoshi、Yokogawa Takashi、Nakagawa Tsutomu、Suzuki Fumiaki、Ebihara Akio
- Journal Title
  
  Heliyon
  
  Volume: 5 Issue: 4 Pages: e01409-e01409
- DOI
  10.1016/j.heliyon.2019.e01409
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01707
[Journal Article] Heavy metals as environmental risk factors for cardiovascular diseases: from the perspective of the renin angiotensin aldosterone system and oxidative stress2019
- Author(s)
  Akther Jobaida、Nabi A. H. M. Nurun、Ebihara Akio
- Journal Title
  
  Reviews in Agricultural Science
  
  Volume: 7 Issue: 0 Pages: 68-83
- DOI
  10.7831/ras.7.0_68
- NAID
  130007690585
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Journal Article] Escherichia coli-based production of recombinant ovine angiotensinogen and its characterization as a renin substrate2016
- Author(s)
  Yamashita S, Shibata N, Boku-Ikeda A, Abe E, Inayama A, Yamaguchi T, Higuma A, Inagaki K, Tsuyuzaki T, Iwamoto S, Ohno S, Yokogawa T, Nishikawa K, Biswas KB, Nabi AH, Nakagawa T, Suzuki F, Ebihara A
- Journal Title
  
  BMC Biotechnology
  
  Volume: 7 Issue: 1 Pages: 33-33
- DOI
  10.1186/s12896-016-0265-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01707
[Presentation] 構造未知タンパク質の可視化と分子機能の推定に向けた AlphaFold2 を用いたインシリコ構造解析と先行研究結果の併用2023
- Author(s)
  杉原大揮、松山誠、中川千春、A. H. M. Nurun Nabi、中川寅、西山成、鈴木文昭、海老原章郎
- Organizer
  第49回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-18KK0273
[Presentation] Functional versatility of (pro)renin receptor clarified by structural and evolutionary analyses2022
- Author(s)
  Daiki Sugihara, Makoto Matsuyama, Chiharu Suzuki-Nakagawa, A.H.M. Nurun Nabi, Tsutomu Nakagawa, Akira Nishiyama, Fumiaki Suzuki and Akio Ebihara
- Organizer
  29th Scientific Meeting of the International Society of Hypertension (ISH2022 Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Presentation] ELISA測定における抗原への処理が抗体結合効率に与える影響－糖尿病合併症早期マーカープロレニンを例として－2022
- Author(s)
  家城孝幸, 島田敦広, 海老原章郎
- Organizer
  日本農芸化学会中部支部第193回例会
- Data Source
  KAKENHI-PROJECT-19K11690
[Presentation] Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis2022
- Author(s)
  Akio Ebihara
- Organizer
  2nd International Conference cum Workshop on "Recent Trends in Structural Bioinformatics and Computer Aided Drug Design" [ICSBCADD'2022]
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Presentation] Development of novel assay systems for non-communicable diseases prevention2019
- Author(s)
  Akio Ebihara
- Organizer
  4th International Conference of Biotechnology on Heath and Agriculture as a joint conference with Innovation in Plant and Food Sciences, IPFS-ICBHA 2019-GNOBB Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11690
[Presentation] Development of novel assay systems for non-communicable diseases prevention2019
- Author(s)
  Akio Ebihara
- Organizer
  4th International Conference of Biotechnology on Heath and Agriculture as a joint conference with Innovation in Plant and Food Sciences, IPFS-ICBHA 2019-GNOBB Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0273
[Presentation] 誰でも簡単に特別な装置なしで抗体を保存する：プルランフィルムに関する研究2018
- Author(s)
  由井翠，寺本好邦，中川寅, 海老原章郎
- Organizer
  日本農芸化学会中部支部第 183 回例会
- Data Source
  KAKENHI-PROJECT-15K01707
[Presentation] Biotechnological production of protein and structure-based evaluation of protein quality2017
- Author(s)
  Akio Ebihara, Tsutomu Nakagawa, and Fumiaki Suzuki
- Organizer
  BIOPROCESSING INDIA 2017 (5th BPI conference)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01707
[Presentation] 抗体結合性を指標とした糖尿病合併症早期マーカータンパク質プロレニンの構造探索2017
- Author(s)
  由井翠、北川まなか、山下晋司、中川寅、鈴木文昭、海老原章郎
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15K01707
[Presentation] 大腸菌発現系を用いた組換えタンパク質の自動発現誘導を促進する添加剤の検討2016
- Author(s)
  田原成康、竹生和代、柴田直哉、鈴木文昭、中川寅、海老原章郎
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-15K01707
[Presentation] 大腸菌発現系を用いた組換え型ヒツジアンジオテンシノーゲンの生産：通気培養槽と自動発現誘導による高収量化2015
- Author(s)
  柴田直哉、山下晋司、朴明宣、大野敏、横川隆志、西川一八、鈴木文昭、中川寅、海老原章郎
- Organizer
  2015年度日本農芸化学会中部・関西支部合同大会
- Place of Presentation
  富山県立大学
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-15K01707
[Presentation] 大腸菌発現系を用いたヒツジアンジオテンシノーゲンの大量生産2013
- Author(s)
  安部江里香、稲山亜由美、山口貴士、朴明宣、大野敏、横川隆志、西川一八、鈴木文昭、中川寅、海老原章郎
- Organizer
  日本農芸化学会2013年度仙台大会
- Place of Presentation
  東北大学・川内キャンパス
- Data Source
  KAKENHI-PROJECT-24658092
[Presentation] A novel production method of recombinant sheep angiotensinogen amenable for clinical assay of plasma renin concentration.2013
- Author(s)
  Akio Ebihara, Erika Abe, Ayumi Inayama, Takashi Yamaguchi, Akiyoshi Boku, Satoshi Ohno, Takashi Yokogawa, Kazuya Nishikawa, Tsutomu Nakagawa, Fumiaki Suzuki.
- Organizer
  European Society of Hypertension　2013
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24658092
[Presentation] ジスルフィド結合形成に着目した大腸菌を用いたヒトプロレニンの生産と特性解析2012
- Author(s)
  田村直希、中原恵子、朴明宣、大野敏、横川隆志、西川一八、鈴木文昭、中川寅、海老原章郎
- Organizer
  第76回日本生化学会中部支部例会
- Place of Presentation
  自然科学研究機構・岡崎コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24658092
[Presentation] 中性で働くアスパラギン酸プロテアーゼ、酵素レニンの結晶構造群の解析：活性部位を構成するアミノ酸残基の立体配置の推定
- Author(s)
  海老原章郎、小林由樹、中川寅、鈴木文昭
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-10-15 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-24658092

1. OHNO Satoshi (10345796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. KAMATARI Yuji O. (70342772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 寺本好邦 (40415716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 橋本美涼 (80805424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 長岡利 (50202221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 松井利郎 (20238942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 本多裕之 (70209328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 島田敦広 (80723874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kitagawa Manaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. Yui Midori

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Yamashita Shinji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. Shibata Naoya

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. Tahara Nariyasu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. Akther Jobaida

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 横川隆志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ebihara Akio 海老原 章郎

EBIHARA Akio 海老原 章郎

Research Projects

Research Products

Co-Researchers

Fundamental research on elucidation of novel biological acceptance mechanisms and innovative applications of food-derived lipid metabolism improving peptides

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Simultaneous on-site measurement of multi-markers associated with microvascular complications and its applications to prediction of diabetic complicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding of the pathobiochemical significance of prorenin, an early marker of diabetic complications: collaborative work between India, Bangladesh and JapanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of point-of-care testing for an early maker of diabetes complicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the molecular mechanism underlining inactivation states of proenzyme and its application for drug designPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mutational landscape of mitochondrial cytochrome b and its flanking tRNA genes associated with increased mitochondrial DNA copy number and disease risk in children with autism2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Production of recombinant His-tagged triple-FLAG peptide in Brevibacillus choshinensis and its utilization as an easy-to-remove affinity peptide2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impacts of SARS-CoV-2 on diabetes mellitus: A pre and post pandemic evaluation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Boosting Auto-Induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-coding Single Nucleotide Variants of Renin and the (Pro)renin Receptor are Associated with Polygenic Diseases in a Bangladeshi Population2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diabetes and Renin-Angiotensin-Aldosterone System: Pathophysiology and Genetics2021

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Establishing a novel assay system for measuring renin concentration using cost effective recombinant ovine angiotensinogen2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heavy metals as environmental risk factors for cardiovascular diseases: from the perspective of the renin angiotensin aldosterone system and oxidative stress2019

Author(s)

Journal Title

DOI

Ebihara Akio 海老原章郎

EBIHARA Akio 海老原章郎