NAGANO Hiromi 永野広海

Researcher Number	60613148
Affiliation (Current)	2022: 鹿児島大学, 医歯学域鹿児島大学病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2022: 鹿児島大学, 医歯学域鹿児島大学病院, 講師 2018 – 2019: 鹿児島大学, 医歯学域医学系, 講師 2015 – 2017: 鹿児島大学, 医歯学域医学系, 助教 2012 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 助教 2011 – 2012: 鹿児島大学, 大学院・医歯学総合研究科, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 経皮免疫 / ホスホリルコリン / 特異的IgA / 粘膜免疫応答 / コレラトキシン / 経皮ワクチン / 粘膜免疫 / ﾏｲｸﾛニードル / 感染症 / 経眼投与 / 鼻腔投与 / IgA … More Except Principal Investigator … More 経鼻免疫 / ホスホリルコリン / ワクチン / 舌下免疫 / 粘膜免疫 / 粘膜ワクチン / 経皮免疫 / 粘膜免疫応答 / アレルギー性鼻炎 / アレルギー / 肺炎球菌 / 経鼻ワクチン / コレラトキシン / 特異的IgA / ﾎｽﾎﾘﾙｺﾘﾝ / ｺﾚﾗﾄｷｼﾝ / 特異的抗体価 / Phoshorylcholine(PC) / PC-KLH / IgA腎症 / 抗炎症作用 / 細菌接着 / バイオフィルム / 抗PC抗体 / インフルエンザ菌 / 二相作用 / ブースター効果 / 血小板活性化因子受容体 / 注射ワクチン / 投与方法 / 追加免疫 / 小児中耳炎 / PCV13 / 肺炎球菌ワクチン / Poly(I:C) / 自然免疫 / Th17 / 上気道感染症 / Poly(I;C) / ホスホリルコリン重合体 / アジュバント作用 / ハプテン作用 / IgE / 結合型ホスホリルコリン重合体 / 細菌接着性 / 粘膜アジュバント / 広域スペクトラム / 結合型ホスホリルコリ重合体（R-MPC） / 結合型ホスホリルコリン / PspA / P6 / 喉頭気管粘膜 / 粘膜傷害抑制 / 気道粘膜再生 / マウス喉頭手術 Less

Intranasolacrimal immunization for induction of secretory IgA responses in the respiratory tract.Principal Investigator
- Principal Investigator
  
  永野広海
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kagoshima University
Research for damage suppression and regenerative therapy in vocal fold mucosa
- Principal Investigator
  
  山下勝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kagoshima University
新規粘膜アジュバントを用いた広域スペクトラムワクチンの開発に関する研究
- Principal Investigator
  
  黒野祐一
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kagoshima University
Toll様受容体リガンドを用いた自然免疫作動型感染症予防・治療薬開発に関する研究
- Principal Investigator
  
  馬越瑞夫
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kagoshima Medical
  Kagoshima University
Development of nasal boost immunization with phosphorylcholine as a novel pneumococcal vaccination program
- Principal Investigator
  
  MASEDA Yoshiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Transcutaneous immunization with phosphorylcholine induces antigen-specific mucosal and systemic immune responsesPrincipal Investigator
- Principal Investigator
  
  Nagano Hiromi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Development of novel mucosal vaccine by applying the biphasic reaction of phosphorylcholine
- Principal Investigator
  
  Kurono Yuichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Application of phosphorylcholine for multi-functional mucosal vaccine
- Principal Investigator
  
  KURONO YUICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Transcutaneous immunization with phosphorylcholine induces antigen-specific mucosal and systemic immune responses in BALB/c micePrincipal Investigator
- Principal Investigator
  
  NAGANO Hiromi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Transcutaneous immunization induces antigen specific mucosal and syatemic immune responses in mice
- Principal Investigator
  
  MASEDA Yoshiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University

All 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Intranasal immunization with phosphorylcholine suppresses allergic rhinitis in mice2018
- Author(s)
  Keiichi Miyashita,MD, Junichiro Ohori,MD,PhD, Hiromi Nagano, MD, Satoshi Fukuyama,MD, PhD, Yuichi Kurono, MD,PhD
- Journal Title
  
  The Laryngoscope
  
  Volume: 128(7)
- DOI
  10.1002/lary.27030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11239
[Journal Article] Mucosal and systemic immune response to sublingual or intranasal immunization with phosphorylcholine2018
- Author(s)
  Maseda Yoshiko、Ohori Junichiro、Tanaka Norimitsu、Nagano Hiromi、Miyashita Keiichi、Kurono Yuichi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 45 Pages: 273-280
- DOI
  10.1016/j.anl.2017.04.009
- NAID
  130007589878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11239
[Journal Article] Transcutaneous immunization in auricle skin induces antigen-specific mucosal and systemic immune responses in BALB/c mice2017
- Author(s)
  Nagano H., Jimura T., Nagano M., Miyashita K., Kurono Y.
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 44 Pages: 411-416
- DOI
  10.1016/j.anl.2016.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11238, KAKENHI-PROJECT-16K11239
[Journal Article] Transcutaneous immunization with phosphorylcholine induces antigen-specific mucosal and systemic immune responses in BALB/c mice.2015
- Author(s)
  Nagano H, Kurono Y,
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 42(6) Pages: 478-482
- NAID
  130005125114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462689
[Journal Article] コレラトキシン経皮免疫による粘膜免疫応答2012
- Author(s)
  永野広海
- Journal Title
  
  日本口腔・咽頭科学会
  
  Volume: 25(1) Pages: 79-84
- NAID
  10030552707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] Transcutaneous immunization with pneumococcal surface protein A in mice2018
- Author(s)
  Hiromi Nagano
- Organizer
  The 17th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11238
[Presentation] PspA経皮ワクチンによる免疫応答の誘導2018
- Author(s)
  永野広海
- Organizer
  第１１９回日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-16K11238
[Presentation] PspA点眼投与による上気道粘膜免疫応答の誘導2018
- Author(s)
  永野広海
- Organizer
  第３６回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-16K11238
[Presentation] PspA点眼投与による上気道粘膜免疫応答の誘導2017
- Author(s)
  永野広海
- Organizer
  第３０回日本口腔・咽頭科学会総会ならびに学術講演会
- Data Source
  KAKENHI-PROJECT-16K11238
[Presentation] 耳介経皮免疫によるホスホリルコリン特異的粘膜免疫応答の誘導2016
- Author(s)
  永野広海
- Organizer
  第１１７回日本耳鼻咽喉科学会通常総会・学術講演会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K11238
[Presentation] 耳介経皮免疫による粘膜免疫応答の誘導2015
- Author(s)
  永野広海
- Organizer
  第２５回日本耳科学会総会学術講演会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-25462689
[Presentation] CTおよびPC経皮免疫による粘膜免疫応答の経時的変化について2014
- Author(s)
  永野広海
- Organizer
  第３２回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  徳島市
- Data Source
  KAKENHI-PROJECT-25861572
[Presentation] CTおよびPC経皮免疫による粘膜免疫応答の経時的変化について2014
- Author(s)
  永野広海
- Organizer
  第３２回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  徳島市
- Data Source
  KAKENHI-PROJECT-25462689
[Presentation] コレラトキシン経皮免疫による粘膜免疫応答2013
- Author(s)
  永野広海
- Organizer
  第２６回日本口腔・咽頭科学会総会学術講演会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-25462689
[Presentation] コレラトキシン経皮免疫による粘膜免疫応答2013
- Author(s)
  永野広海
- Organizer
  第２６回日本口腔・咽頭科学会総会学術講演会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-25861572
[Presentation] PC経皮免疫による粘膜免疫応答の誘導2013
- Author(s)
  永野広海
- Organizer
  第１１４回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-25861572
[Presentation] PC経皮免疫による粘膜免疫応答の誘導2013
- Author(s)
  永野広海
- Organizer
  第１１４回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-25462689
[Presentation] PC経皮免疫による粘膜免疫応答の誘導2013
- Author(s)
  永野広海
- Organizer
  第３１回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  倉敷市
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] PC 経皮免疫による粘膜免疫応答の誘導2013
- Author(s)
  永野広海
- Organizer
  第31回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  倉敷
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] PC経皮免疫による粘膜免疫応答の誘導2012
- Author(s)
  永野広海
- Organizer
  第１０回日本ワクチン学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] Transcutaneous immunization with cholera toxin in BALB/c mice2012
- Author(s)
  H.Nagano
- Organizer
  The 14th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] コレラトキシン経皮免疫による粘膜免疫応答の誘導2012
- Author(s)
  永野広海
- Organizer
  第30回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  大津市
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] Transcutaneous immunization with cholera toxin in BALB/C mice.2012
- Author(s)
  H. Nagano
- Organizer
  he 14thJapan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] PC 経皮免疫による粘膜免疫応答の誘導2012
- Author(s)
  永野広海
- Organizer
  第10回日本ワクチン学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] Phosphorylcholineを用いた経皮免疫について2011
- Author(s)
  永野広海
- Organizer
  第26回九州連合地方部会学術講演会
- Place of Presentation
  久留米市
- Year and Date
  2011-07-10
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] コレラトキシン経皮免疫による口腔粘膜免疫応答の誘導2011
- Author(s)
  永野広海
- Organizer
  第24回日本口腔・咽頭科学会総会学術講演会
- Place of Presentation
  広島市
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22591911
[Presentation] ヒアルロン酸マイクロニードルを用いた経皮免疫
- Author(s)
  永野広海
- Organizer
  第３３回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  東京（東武ホテルレバント東京）
- Year and Date
  2015-02-26 – 2015-02-28
- Data Source
  KAKENHI-PROJECT-25861572
[Presentation] ヒアルロン酸マイクロニードルを用いた経皮免疫
- Author(s)
  永野広海
- Organizer
  第33回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  東京(東武ホテルレバント東京)
- Year and Date
  2015-02-26 – 2015-02-28
- Data Source
  KAKENHI-PROJECT-25462689

1. KURONO Yuichi (80153427)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
2. MIYASHITA Keiichi (30585063)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
3. 大堀純一郎 (90507162)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
4. KAWABATA MASAKI (30585112)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. MAKISE Takao (30585120)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
6. MASEDA Yoshiko (70535666)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 地村友宏 (10709596)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. 井内寛之 (90645285)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 山下勝 (10635519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 宮之原郁代 (40305131)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 田淵みな子 (90838187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. MATSUNE Shoji (00253899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 原田みずえ (20585103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 馬越瑞夫 (30596325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 丸山征郎 (20082282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGANO Hiromi 永野 広海

Research Projects

Research Products

Co-Researchers

Intranasolacrimal immunization for induction of secretory IgA responses in the respiratory tract.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for damage suppression and regenerative therapy in vocal fold mucosa

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規粘膜アジュバントを用いた広域スペクトラムワクチンの開発に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Toll様受容体リガンドを用いた自然免疫作動型感染症予防・治療薬開発に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of nasal boost immunization with phosphorylcholine as a novel pneumococcal vaccination program

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcutaneous immunization with phosphorylcholine induces antigen-specific mucosal and systemic immune responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel mucosal vaccine by applying the biphasic reaction of phosphorylcholine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of phosphorylcholine for multi-functional mucosal vaccine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcutaneous immunization with phosphorylcholine induces antigen-specific mucosal and systemic immune responses in BALB/c micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcutaneous immunization induces antigen specific mucosal and syatemic immune responses in mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Intranasal immunization with phosphorylcholine suppresses allergic rhinitis in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mucosal and systemic immune response to sublingual or intranasal immunization with phosphorylcholine2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Transcutaneous immunization in auricle skin induces antigen-specific mucosal and systemic immune responses in BALB/c mice2017

Author(s)

Journal Title

DOI

Data Source

NAGANO Hiromi 永野広海