Numaga-Tomita Takuro 冨田拓郎 (沼賀拓郎)

… Alternative Names

沼賀拓郎

冨田拓郎(沼賀拓郎) トミタタクロウ

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Researcher Number	60705060
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院医学系, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 信州大学, 学術研究院医学系, 准教授 2018: 大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 助教 2014 – 2017: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教 2014: 九州大学, 薬学研究科(研究院), 助教 2013: 九州大学, 学内共同利用施設等, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Basic Section 47040:Pharmacology-related / General pharmacology / Complex systems / General medical chemistry / Dermatology Except Principal Investigator Basic Section 48020:Physiology-related / Basic Section 55050:Anesthesiology-related
Keywords	Principal Investigator 冠血管 / 交感神経 / 筋萎縮 / 運動 / TRPCチャネル / 血管平滑筋 / 活性酸素 / 生理学 / 活性酸素種 / 血管成熟 … More / 創傷治癒 / 心臓発達 / 壁細胞 / がん / 血管形成 / 細胞内カルシウム伝達 / 血管新生 / L型カルシウムチャネル / 神経成長因子 / 電位依存性L型カルシウムチャネル / TRPC6 / 内皮障害 / 血流回復 / TRPC6チャネル / カルシウム / 運動模倣薬 / 末梢血流 / 機械的刺激 / 末梢循環調節 / 薬学 / 循環器・高血圧 / 自発運動 / 心筋細胞 / シグナル伝達 / 宇宙空間 / 心臓線維化 / Caシグナル / 薬理学 / 細胞・組織 / NADPH oxidase 2 / TRPC3チャネル / 心臓リモデリング / 機械的ストレス / 細胞外マトリクス / 心血管細胞 / メカノバイオロジー / 炎症 / カルシウムシグナリング … More Except Principal Investigator カルシウムイオン / 筋小胞体 / 骨格筋 / 興奮収縮連関 / カルシウムチャネル / リアノジン受容体 / 疼痛 / NaV1.7 / 鎮痛 / 無痛症 / 電位依存性ナトリウムチャネル / カルシウム遊離チャネル / 筋収縮 / クライオ電子顕微鏡 / イオンチャネル / 機能解析 / 創薬 / 構造解析 / 悪性高熱症 / サブタイプ / 小胞体 Less

血管リモデリングにおけるC末端チロシンリン酸化CaV1.2の重要性の解明Principal Investigator
- Principal Investigator
  
  冨田拓郎 (沼賀拓郎)
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Shinshu University
出生後心臓の冠血管・交感神経ネットワーク形成の原理と心臓発達における重要性の解明Principal Investigator
- Principal Investigator
  
  冨田拓郎 (沼賀拓郎)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Shinshu University
Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system
- Principal Investigator
  
  村山尚
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
無痛症のメカニズムの解明：生体内におけるNaV1.7変異が与える影響
- Principal Investigator
  
  中村博之
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Shinshu University
Analysis of the molecular and cellular mechanism of vessel maturation in adult tissuesPrincipal Investigator
- Principal Investigator
  
  Numaga-Tomita Takuro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Shinshu University
Molecular basis of subtype-specific channel regulation using novel ryanodine receptor modulators
- Principal Investigator
  
  Murayama Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
骨格筋および末梢循環における力学的負荷の重要性の解明Principal Investigator
- Principal Investigator
  
  冨田拓郎 (沼賀拓郎)
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Shinshu University
  Center for Novel Science Initatives, National Institutes of Natural Sciences
Cardiovascular protective effect by adaptation and maintenance in response to continuous exercise trainingPrincipal Investigator
- Principal Investigator
  
  Tomita Takuro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
  Okazaki Research Facilities, National Institutes of Natural Sciences
宇宙生活での健康リスク低減を目指した運動による生体恒常性の頑健性獲得機構の解明Principal Investigator
- Principal Investigator
  
  冨田拓郎 (沼賀拓郎)
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Okazaki Research Facilities, National Institutes of Natural Sciences
Study of physiological importance of extracellular microenvironment on neovascularization through a development of multi dimentional co-culture system.Principal Investigator
- Principal Investigator
  
  Numaga-Tomita Takuro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Okazaki Research Facilities, National Institutes of Natural Sciences
皮膚表皮カルシウムホメオスタシスの創傷治癒における生理的意義の解明Principal Investigator
- Principal Investigator
  
  冨田拓郎 (沼賀拓郎)
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Dermatology
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 Other

All Journal Article Presentation Patent

[Journal Article] A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.2022
- Author(s)
  Shimauchi T, Numaga-Tomita T, Kato Y, Morimoto H, Sakata K, Matsukane R, Nishimura A, Nishiyama K, Shibuta A, Horiuchi Y, Kurose H, Kim SG, Urano Y, Ohshima T, Nishida M.
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 13 Pages: 2041-2041
- DOI
  10.3390/cells11132041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06646, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05208, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H02607, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-23K24035
[Journal Article] NRSF- GNAO1 Pathway Contributes to the Regulation of Cardiac Ca 2+ Homeostasis2022
- Author(s)
  Inazumi Hideaki、Kuwahara Koichiro、Nakagawa Yasuaki、et al.
- Journal Title
  
  Circulation Research
  
  Volume: 130 Issue: 2 Pages: 234-248
- DOI
  10.1161/circresaha.121.318898
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07297, KAKENHI-PROJECT-19K08580, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-20H03673, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K07299, KAKENHI-PROJECT-21K08126, KAKENHI-PROJECT-20K17077, KAKENHI-PROJECT-22K08099
[Journal Article] A reconstituted depolarization-induced Ca2+ release platform for validation of skeletal muscle disease mutations and drug discovery2022
- Author(s)
  Murayama Takashi、Kurebayashi Nagomi、Numaga-Tomita Takuro、Kobayashi Takuya、Okazaki Satoru、Yamashiro Kyosuke、Nakada Tsutomu、Mori Shuichi、Ishida Ryosuke、Kagechika Hiroyuki、Yamada Mitsuhiko、Sakurai Takashi
- Journal Title
  
  Journal of General Physiology
  
  Volume: 154 Issue: 12
- DOI
  10.1085/jgp.202213230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K06828, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
[Journal Article] Inhibition of transient receptor potential cation channel?6 promotes capillary arterialization during post‐ischaemic blood flow recovery2022
- Author(s)
  Numaga‐Tomita Takuro、Shimauchi Tsukasa、Kato Yuri、Nishiyama Kazuhiro、Nishimura Akiyuki、Sakata Kosuke、Inada Hiroyuki、Kita Satomi、Iwamoto Takahiro、Nabekura Junichi、Birnbaumer Lutz、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 180 Issue: 1 Pages: 94-110
- DOI
  10.1111/bph.15942
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19395, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-20K07302, KAKENHI-PROJECT-23K24035
[Journal Article] Gravity sensing in plant and animal cells.2021
- Author(s)
  Takahashi K, Takahashi H, Furuichi T, Toyota M, Furutani-Seiki M, Kobayashi T, Watanabe-Takano H, Shinohara M, Numaga-Tomita T, Sakaue-Sawano A, Miyawaki A, Naruse K.
- Journal Title
  
  NPJ Microgravity
  
  Volume: 7 Issue: 1 Pages: 2-2
- DOI
  10.1038/s41526-020-00130-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-20K08956, KAKENHI-PROJECT-20K21896, KAKENHI-PLANNED-18H05491, KAKENHI-PROJECT-19H03140, KAKENHI-PROJECT-18K09050, KAKENHI-PROJECT-18K19291, KAKENHI-PROJECT-19H03991
[Journal Article] beta-Arrestin-Biased AT1 Agonist, TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect without Increasing Heart Rate2020
- Author(s)
  Kashihara T, Kawagishi H, Nakada T, Numaga-Tomita T, Kadota S, Wolf EE, Du CK, Shiba Y, Morimoto S, Yamada M.
- Journal Title
  
  Journal of the American College of Cardiology
  
  Volume: 5 Issue: 11 Pages: 1057-1057
- DOI
  10.1016/j.jacbts.2020.08.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K07299, KAKENHI-PROJECT-18K06870, KAKENHI-PROJECT-19K16488
[Journal Article] TRPC Channels in Cardiac Plasticity2020
- Author(s)
  Numaga-Tomita Takuro、Nishida Motohiro
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 2 Pages: 454-454
- DOI
  10.3390/cells9020454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07116, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293
[Journal Article] TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential‐dependent coupling with PTEN2019
- Author(s)
  Numaga‐Tomita Takuro、Shimauchi Tsukasa、Oda Sayaka、Tanaka Tomohiro、Nishiyama Kazuhiro、Nishimura Akiyuki、Birnbaumer Lutz、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 9 Pages: 9785-9796
- DOI
  10.1096/fj.201802811r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K07116, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J14538, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19H03383, KAKENHI-ORGANIZER-15H05935
[Journal Article] TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy2019
- Author(s)
  Sudi Suhaini Binti、Tanaka Tomohiro、Oda Sayaka、Nishiyama Kazuhiro、Nishimura Akiyuki、Sunggip Caroline、Mangmool Supachoke、Numaga-Tomita Takuro、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 9785-9785
- DOI
  10.1038/s41598-019-46252-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K16363, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J14538, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC channels in exercise-mimetic therapy.2018
- Author(s)
  Numaga-Tomita T, Oda S, Nishiyama K, Tanaka T, Nishimura A, Nishida M.
- Journal Title
  
  Pflugers Archiv European Journal of Physiology
  
  Volume: 471 Issue: 3 Pages: 507-517
- DOI
  10.1007/s00424-018-2211-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H05092, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-19J14538, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy.2018
- Author(s)
  Sunggip C, Shimoda K, Oda S, Tanaka T, Nishiyama K, Mangmool S, Nishimura A, Numaga-Tomita T and Nishida M
- Journal Title
  
  Front. Pharmacol.
  
  Volume: 9 Pages: 523-523
- DOI
  10.3389/fphar.2018.00523
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15585, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293, KAKENHI-ORGANIZER-15H05935
[Journal Article] TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice2017
- Author(s)
  Oda Sayaka、Numaga-Tomita Takuro、Kitajima Naoyuki、Toyama Takashi、Harada Eri、Shimauchi Tsukasa、Nishimura Akiyuki、Ishikawa Tatsuya、Kumagai Yoshito、Birnbaumer Lutz、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 7511-7511
- DOI
  10.1038/s41598-017-07903-4
- NAID
  120007128849
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15488, KAKENHI-PROJECT-17K15585, KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy2017
- Author(s)
  Shimauchi Tsukasa、Numaga-Tomita Takuro、Ito Tomoya、Nishimura Akiyuki、Matsukane Ryosuke、Oda Sayaka、Hoka Sumio、Ide Tomomi、Koitabashi Norimichi、Uchida Koji、Sumimoto Hideki、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  The JCI insight
  
  Volume: 2 Issue: 15 Pages: 93358-93358
- DOI
  10.1172/jci.insight.93358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15585, KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-26111009, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092
[Journal Article] TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.2016
- Author(s)
  Kitajima N., Numaga-Tomita T., Watanabe M., Kuroda T., Nishimura A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L., Sumimoto H., Mori Y. and Nishida M
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 37701-37701
- DOI
  10.1038/srep37001
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-26111009, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-26293187, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K15442
[Journal Article] The purinergic P2Y6 receptor heterodimerizes with the angiotensin AT1 receptor to promote angiotensin II-induced hypertension2016
- Author(s)
  A. Nishimura, C. Sunggip, H. Tozaki-Saitoh, T. Shimauchi, T. Numaga-Tomita, K. Hirano, T. Ide, J-M. Boeynaems, H. Kurose, M. Tsuda, B. Robaye, K. Inoue and M. Nishida
- Journal Title
  
  Science Signaling
  
  Volume: Jan 19;9(411) Issue: 411
- DOI
  10.1126/scisignal.aac9187
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-26670144, KAKENHI-PLANNED-25117013, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25253011
[Journal Article] TRPC3 amplifies B cell receptor-induced ERK signaling via protein kinase D-dependent Rap1 activation2016
- Author(s)
  T. Numaga-Tomita, M. Nishida, J.W. Jr. Putney and Y. Mori
- Journal Title
  
  Biochem J
  
  Volume: 473(2) Issue: 2 Pages: 201-210
- DOI
  10.1042/bj20150596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-24249017, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-26670144, KAKENHI-PLANNED-26111011
[Journal Article] TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.2016
- Author(s)
  Numaga-Tomita T., Kitajima N., Kuroda T., Nishimura A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L., Sumimoto H., Mori Y. and Nishida M.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 39383-39383
- DOI
  10.1038/srep39383
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01656, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-26111009, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-26293187, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K15442
[Patent] ベンゾイソオキサゾール化合物2018
- Inventor(s)
  永田龍、森泰生、西田基宏、森誠之、冨田拓郎
- Industrial Property Rights Holder
  大阪大学、京都大学、自然科学研究機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-086929
- Filing Date
  2018
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Patent] ベンゾイソオキサゾール化合物2018
- Inventor(s)
  永田龍、森泰生、西田基宏、森誠之、冨田拓郎
- Industrial Property Rights Holder
  永田龍、森泰生、西田基宏、森誠之、冨田拓郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-086929
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] Analysis of molecular mechanism underlying STIM1-mediated suppression of CaV1.22024
- Author(s)
  冨田　拓郎
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06842
[Presentation] The importance of sympathetic innervation for the postnatal heart development2023
- Author(s)
  冨田　拓郎
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06842
[Presentation] 出産後心臓発達における交感神経支配の重要性の解明2022
- Author(s)
  冨田　拓郎、川岸　裕幸、中田　勉、山田　充彦
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] 骨格筋疾患治療薬開発のための脱分極誘発性Ca2+遊離再構成プラットフォームの構築2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、石田良典、森修一、影近弘之、山田充彦、櫻井隆．
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K24067
[Presentation] 骨格筋脱分極誘発性Ca2+遊離（DICR）再構成系の開発2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、山田充彦、櫻井隆
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 骨格筋脱分極誘発性Ca2+遊離（DICR）再構成系の開発2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、山田充彦、櫻井隆
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24067
[Presentation] 骨格筋疾患治療薬開発のための脱分極誘発性Ca2+遊離再構成プラットフォームの構築2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、石田良典、森修一、影近弘之、山田充彦、櫻井隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 交感神経除神経が新生児心臓発達に与える影響の解析2021
- Author(s)
  冨田　拓郎、川岸　裕幸、中田　勉、山田　充彦
- Organizer
  第144回薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] 交感神経除神経が新生児・乳児の心臓発達に与える影響の解析2021
- Author(s)
  冨田　拓郎, 川岸　裕幸, 中田　勉, 山田　充彦
- Organizer
  第31回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] The effect of chemical sympathetic innervation on the postnatal heart development.2021
- Author(s)
  冨田　拓郎、川岸　裕幸、中田　勉、山田　充彦
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] 血管平滑筋細胞におけるL型電位依存性カルシウムチャネルとストア作動性カルシウムチャネルの関係性解明2020
- Author(s)
  冨田　拓郎、小林　誠、川岸　裕幸、中田　勉、山田　充彦
- Organizer
  日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] Analysis of the molecular mechanism underlying ER Ca2+ sensor STIM1-dependent suppression of CaV1.22020
- Author(s)
  Takuro Numaga-Tomita, Hiroki Takahashi, Mitsuhiko Yamada
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] Analysis of the molecular mechanism underlying ER Ca2+ sensor STIM1-dependent suppression of CaV1.2 channel activity2020
- Author(s)
  Takuro Numaga-Tomita, Hiroki Takahashi, Mitsuhiko Yamada
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] Physiological and pathophysiological significance of TRPC3-Nox2 coupling in the heart2019
- Author(s)
  Takuro Numaga-Tomita, Tsukasa Shimauchi, Naoyuki Kitajma, Akiyuki Nishimura, Motohiro Nishid
- Organizer
  9th FAOPS congress
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] 小胞体CaセンサーSTIM1によるCav1.2チャネル制御機構の解明2019
- Author(s)
  冨田拓郎、高橋弘毅、山田充彦
- Organizer
  第66回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] Physiological and pathophysiological significance of TRPC3-Nox2 coupling in the heart2019
- Author(s)
  Takuro Numaga-Tomita, Tsukasa Shimauchi, Naoyuki Kitajma, Akiyuki Nishimura, and Motohiro Nishida
- Organizer
  9th FAOPS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] 血管平滑筋の表現型スイッチにおけるTRPC6チャネルの重要性の解明2019
- Author(s)
  冨田拓郎、西田基宏
- Organizer
  日本循環薬理学会
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] TRPC6 plays a critical role in phenotype switching of vascular smooth muscle cells by physical and functional coupling with PTEN via membrane potential.2019
- Author(s)
  Takuro Numaga-Tomita, Akiyuki Nishimura and Motohiro Nishida
- Organizer
  日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] 小胞体CaセンサーSTIM1によるCav1.2チャネル制御機構の解明2019
- Author(s)
  冨田拓郎、高橋弘穀、山田充彦
- Organizer
  中部日本生理学会
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] Importance of TRPC3-Nox2 coupling in cardiac stiffness2019
- Author(s)
  Numaga-Tomita T, Shimauchi T, Kitajima N, Nishimura A, Nishida M
- Organizer
  8th International Workshop Cardiac Mechano-Electric Coupling and Arrhythmias
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] 血管平滑筋の表現型スイッチにおけるTRPC6チャネルの重要性の解明2019
- Author(s)
  Takuro Numaga-Tomita, Akiyuki Nishimura, Motohiro Nishida
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] TRPC6 plays a critical role in phenotype switching of vascular smooth muscle cells by physical and functional coupling with PTEN via membrane potential.2019
- Author(s)
  Takuro Numaga-Tomita, Akiyuki Nishimura and Motohiro Nishida
- Organizer
  日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] Importance of TRPC3-Nox2 Coupling in Cardiac Stiffness2019
- Author(s)
  "Numaga-Tomita T, Shimauchi T, Kitajima N, Nishimura A, Nishida M"
- Organizer
  "8th International Workshop Cardiac Mechano-Electric Coupling and Arrhythmias"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] 血管平滑筋の表現型スイッチにおけるTRPC6チャネルの重要性の解明2019
- Author(s)
  冨田拓郎、西田基宏
- Organizer
  第29回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-19K07116
[Presentation] Physiological and pathophysiological significance of TRPC3-Nox2 coupling in the heart2019
- Author(s)
  Takuro Numaga-Tomita, Tsukasa Shimauchi, Naoyuki Kitajma, Akiyuki Nishimura, and Motohiro Nishida
- Organizer
  9th FAOPS
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04993
[Presentation] Positive regulation of Nox2 by TRPC3 channel mediates pathological cardiac remodeling2018
- Author(s)
  冨田拓郎、島内司、小田紗矢香、北島直幸、西村明幸、西田基宏
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PUBLICLY-16H01656
[Presentation] 筋組織恒常性維持を目指したTRPC-Nox機能連関を標的とする創薬研究2018
- Author(s)
  冨田拓郎、島内司、小田紗矢香、西村明幸、西田基宏
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] 筋組織恒常性維持を目指したTRPC-Nox機能連関を標的とする創薬研究2018
- Author(s)
  冨田拓郎、島内司、小田紗矢香、西村明幸、西田基宏
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01656
[Presentation] Positive regulation of Nox2 by TRPC3 channel mediates pathological cardiac remodeling2018
- Author(s)
  冨田拓郎、島内司、小田紗矢香、北島直幸、西村明幸、西田基宏
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] Positive regulation of Nox2 by TRPC3 channel mediates mechanical stress-induced cardiac fibrosis.2017
- Author(s)
  Takuro Numaga-Tomita, Naoyuki Kitajima, Akiyuki Nishimura, and Motohiro Nishida
- Organizer
  The Korean Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01656
[Presentation] Positive regulation of Nox2 by TRPC3 channel mediates mechanical stress-induced cardiac fibrosis.2017
- Author(s)
  Takuro Numaga-Tomita, Naoyuki Kitajima, Akiyuki Nishimura, and Motohiro Nishida
- Organizer
  The Korean Society of Cardiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] 心臓の線維化におけるTRPC3-Nox2機能連関の役割2017
- Author(s)
  冨田　拓郎, 島内　司, 西村　明幸, 西田　基宏
- Organizer
  日本生理学会大会
- Place of Presentation
  アクトシティ浜松、静岡県浜松市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PUBLICLY-16H01656
[Presentation] TRPC3-Nox2機能連関によるROS産生と心臓リモデリング2017
- Author(s)
  冨田拓郎、北島直幸、西村明幸、西田基宏
- Organizer
  第17回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15585
[Presentation] TRPCチャネル阻害による末梢循環改善作用の解明2017
- Author(s)
  冨田　拓郎, 島内　司, 西村　明幸, 西田　基宏
- Organizer
  日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール、長崎県長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PUBLICLY-16H01656
[Presentation] TRPC3-Nox2機能連関によるROS産生と心臓リモデリング2017
- Author(s)
  冨田拓郎、北島直幸、西村明幸、西田基宏
- Organizer
  第17回日本NO学会学術集会
- Data Source
  KAKENHI-PUBLICLY-16H01656
[Presentation] B細胞受容体刺激に惹起されるERK活性化におけるTRPC3を介したシグナル伝達機構の解明2016
- Author(s)
  冨田（沼賀）拓郎、西田基宏、James W, Putney, Jr.、森泰生
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  北海道、札幌市、札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26670144
[Presentation] Role of STIM1- and Orai1-mediated Ca2+ entry in epidermal keratinocyte physiology2014
- Author(s)
  冨田　拓郎
- Organizer
  第９１回日本生理学会大会
- Place of Presentation
  鹿児島大学　郡元キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-25893165
[Presentation] TRPCチャネルによる末梢循環調節とその治療応用
- Author(s)
  冨田拓郎
- Organizer
  日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル　神奈川県横浜市
- Year and Date
  2014-08-07 – 2014-08-08
- Invited
- Data Source
  KAKENHI-PROJECT-26670144
[Presentation] 下肢虚血後の運動機能障害におけるTRPC6チャネル欠損の効果
- Author(s)
  冨田拓郎
- Organizer
  日本薬理学会年会
- Place of Presentation
  名古屋国際会議場愛知県名古屋市
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26670144

1. Murayama Takashi (10230012)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 呉林なごみ (50133335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 小林琢也 (60468585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 小川治夫 (40292726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 井上華 (20390700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 杉原匡美 (80648163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中村博之 (20838370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中聡 (60293510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石田高志 (60531952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石田公美子 (80467191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Nishimura Akiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 黒瀬等

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 西田基宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
14. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
15. 西山和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 石田良典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Numaga-Tomita Takuro 冨田 拓郎 (沼賀 拓郎)

沼賀 拓郎

沼賀拓郎

冨田 拓郎(沼賀拓郎) トミタ タクロウ

Research Projects

Research Products

Co-Researchers

血管リモデリングにおけるC末端チロシンリン酸化CaV1.2の重要性の解明Principal Investigator

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出生後心臓の冠血管・交感神経ネットワーク形成の原理と心臓発達における重要性の解明Principal Investigator

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Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system

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無痛症のメカニズムの解明：生体内におけるNaV1.7変異が与える影響

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Analysis of the molecular and cellular mechanism of vessel maturation in adult tissuesPrincipal Investigator

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Molecular basis of subtype-specific channel regulation using novel ryanodine receptor modulators

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骨格筋および末梢循環における力学的負荷の重要性の解明Principal Investigator

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Cardiovascular protective effect by adaptation and maintenance in response to continuous exercise trainingPrincipal Investigator

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宇宙生活での健康リスク低減を目指した運動による生体恒常性の頑健性獲得機構の解明Principal Investigator

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Study of physiological importance of extracellular microenvironment on neovascularization through a development of multi dimentional co-culture system.Principal Investigator

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皮膚表皮カルシウムホメオスタシスの創傷治癒における生理的意義の解明Principal Investigator

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[Journal Article] A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.2022

Author(s)

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[Journal Article] NRSF- GNAO1 Pathway Contributes to the Regulation of Cardiac Ca 2+ Homeostasis2022

Author(s)

Journal Title

Numaga-Tomita Takuro 冨田拓郎 (沼賀拓郎)

沼賀拓郎

冨田拓郎(沼賀拓郎) トミタタクロウ