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Tomoda Hiroshi  供田 洋

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… Alternative Names

TOMODA Hiroshi  共田 洋

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Researcher Number 70164043
Other IDs
External Links
Affiliation (Current) 2025: 北里大学, 薬学部, 特任教授
Affiliation (based on the past Project Information) *help 2020 – 2023: 北里大学, 薬学部, 特任教授
2014 – 2019: 北里大学, 薬学部, 教授
2005 – 2012: 北里大学, 薬学部, 教授
2001 – 2004: 北里大学, 北里生命科学研究所, 教授
2003: 北里大学, 生命科学研究所, 教授 … More
1999: 社団法人 北里研究所, 生物機能研究所, 副所長
1999: Research Center for Biological Function, The Kitasato Institute, Director, 生物機能研究所, 副所長
1998: 北里研究所, 生物機能研究所, 副所長
1997: The Kitasato Institute, Researach Center for Biological Function, Chief Researac, 生物機能研究所, 副所長
1996: (社)北里研究所, 生物機能研究所, 室長
1996: 北里研究所, 生物機能研究所, 室長
1995: 北里研究所, 生物機能研究所, 副部長
1995: 社団法人北里研究所, 生物機能研究所, 室長
1994: 北里研究所, 抗生物質研究室, 副部長
1991 – 1992: 北里研究所, 生物機能研究所, 室長
1990: 北里研究所, 研究部, 室長 Less
Review Section/Research Field
Principal Investigator
Natural medicines / Medium-sized Section 47:Pharmaceutical sciences and related fields / Bioorganic chemistry / Living organism molecular science / Chemical pharmacy / Science and Engineering
Except Principal Investigator
Biological pharmacy / Chemical pharmacy / Biomolecular chemistry / Conservation of biological resources / 応用微生物学 / Chemical pharmacy
Keywords
Principal Investigator
ケミカルバイオロジー / 脂質代謝 / 創薬 / CETP / 循環器・高血圧 / 医療・福祉 / 感染症 / 阻害剤 / 探索 / ライブラリー … More / シード探索 / ライブラリ / 天然資源 / 機能分子 / 抗生物質 / 制御分子 / 微生物 / 脂質 / 生化学 / 天然物化学 / 微生物資源 / 脂肪肝 / 動脈硬化 / Erabulenol / Ferroverdin / cholesteryl ester / microbial origin / inhibitor / 糸状菌代謝産物 / エラブレノール / 放射菌代謝産物 / Pyripyropene誘導体 / Ferroveridin類 / 微生物由来阻害剤 / コレステリルエステル転送蛋白質 / 微生物代謝産物 / ビアリルカップリング酵素 / マルチ銅オキシダーゼ / ダイナピノンA / ビアリルカップリングエンザイム / マルチカッパーオキシダーゼ / 二量体化 / ケミカルバイォロジー / 結合タンパク質 / 標的分子 / 天然物 / ACATアイソザイム / ACAT アイソザイム / 動脈硬化症 / 医療福祉 / トリグリセリド / 中性脂肪 / コレステロール / 微生物由来機能分子 … More
Except Principal Investigator
ACAT / CETP / 阻害剤 / Inhibitor / 誘導体合成 / LDL / HDL / ピリピロペン / コレステロール / マクロファージ / 蛋白質 / 脳・神経 / G蛋白質共役型受容体 / シクロオキシゲナーゼ / 遺伝子欠損マウス / プロスタグランジン / 酵素 / G蛋白質結合型受容体 / 結晶構造解析 / 脂質メディエーター / 受容体拮抗薬 / 酵素阻害剤 / 外傷性脳障害 / 結晶構造 / 阻害薬 / プロスタグランジンD2 / 睡眠物質 / 危険性薬物 / 癌 / サプリメント / 血管新生 / 筋ジストロフィー / 肥満 / 炎症 / 睡眠 / 新興感染症 / 生態系保全 / 病原体 / 宿主 / 両生類 / カエルツボカビ / Inducers of microbial growth / New bioactive compounds / Catalase / Superoxide dismutase / Superoxide / Unknown microorganisms / Micobial resources / グラム陽性高G+Cバクテリア / 休眠細胞活性化因子 / SOD / 微生物生育増強因子 / 新規有用物質 / カタラーゼ / スーパーオキシドジスムターゼ / 活性酸素 / 未利用微生物 / 微生物資源 / synthesis of derivatives / marine products / elucidation of structure / purification of active compounds / plant resource / microbial resource / chemistry of natural products / antimalarial drugs / 海洋生物素材 / 活性物質の構造決定 / 活性物質の精製 / 植物素材 / 微生物素材 / 天然物化学 / 抗マラリア剤 / Andrastin / Ras protein / Acly-Coa synthetase / Triacsin / HIV Gag protein / Farnesyltransferase / Myristoylation / 抗エイズ剤 / アシル化 / 脂質修飾蛋白質 / 抗癌剤 / 抗エイズ薬 / アンドラスチン / Ras蛋白質 / アシルCoA合成酵素 / トリアクシン / HIV Gag蛋白質 / ファルネシル化 / ミリストイル化 / Biosynthesis / Total synthesis / Structure-activity relationship / Pyripyropene / Fungal metabolite / Acyl-CoA : cholesterol acyltransferase / アシルCoA:コレステロールアシル転移酵素 / 全合成 / アシルCoA:コレスチロールアシル転移酵素 / コレステロール代謝 / コレステリルエステル転送蛋白質 / コレステロール代謝阻害剤 / 生合成 / 金合成 / 構造活性相関 / カビ代謝産物 / アシルCoAコレステロールアシル転移酵素 / SRBI / Macropage / Choresterol / スフィンゴミエリン / ホスファチジルコリン / アポE / 動脈硬化 / トランスポート / ライソソーム / リポ蛋白質 / 変性LDL / スカベンジャー受容体 / SRB1 / cholesterol transport / cholesterol / steroid / azole / ACAT inhibitor / foam cell / macrophage / 細胞内輸送 / コレステロ-ル / パ-パクチン / 抗真菌剤 / シクロデプシペプチド / マクロファ-ジ / グリソプレニン / コレステロール輸送 / ステロイド系阻害剤 / アゾール系抗真菌剤 / ACAT阻害剤 / 泡沫化 / 抗結核剤 / カルピナクタム / 固相合成 / 天然物 / ペプチド / 抗結核薬 / レチノイン酸(retinoic acid) / 抗生物質(antibiotics) / チロシンキナーゼ / adhesion(接着) / apoptosis(アポトーシス) / Leukemia(白血病) / 生物活性物質 / ホヤ / 海綿 / 海洋糸状菌 / 血管新生阻害 / 殺がん細胞活性 / 有糸分裂阻害 / 微小管重合阻害 Less
  • Research Projects

    (18 results)
  • Research Products

    (161 results)
  • Co-Researchers

    (54 People)
  •  Collection and utilization of bioresources and natural products from IndonesiaPrincipal Investigator

    • Principal Investigator
      Tomoda Hiroshi
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Kitasato University
  •  Interaction between brain function and inflammation mediated by prostaglandin D2

    • Principal Investigator
      Urade Yoshihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      The University of Tokyo
      University of Tsukuba
  •  Why do not die Japanese frogs with chytrid fungus.

    • Principal Investigator
      UNE Yumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservation of biological resources
    • Research Institution
      Azabu University
  •  Study on the regioselective coupling reaction to produce atropisomers by enzymePrincipal Investigator

    • Principal Investigator
      Tomoda Hiroshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Natural medicines
    • Research Institution
      Kitasato University
  •  Study on microbial inhibitors of lipid metabolism regulatory activity.Principal Investigator

    • Principal Investigator
      Tomoda Hiroshi
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Natural medicines
    • Research Institution
      Kitasato University
  •  Development of anti-tuberculosis drugs based on calpinactam

    • Principal Investigator
      NAGAI Kenichiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kitasato University
  •  THE CHEMICAL BIOLOGY OF NEW MICROBIAL ANTI-INFECTIVE AGENTSPrincipal Investigator

    • Principal Investigator
      TOMODA Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Kitasato University
  •  Discovery and development of selectivity-defined inhibitors toward two acyl-CoA : cholesterol acyltransferase isozymesPrincipal Investigator

    • Principal Investigator
      TOMODA Hiroshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kitasato University
  •  脂質代謝を制御する機能分子プローブの創製Principal Investigator

    • Principal Investigator
      供田 洋
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kitasato University
  •  Isolation and application of new microorganisms from soil Samples

    • Principal Investigator
      TAKAHASHI Yoko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学
    • Research Institution
      Kitasato University
  •  Research of the antimalarial drugs from the natural products

    • Principal Investigator
      OMURA Satoshi
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kitasato University
      Kitasato Institute
  •  Screening for inhibitors of Cholesteryl Ester Transfer ProteinPrincipal Investigator

    • Principal Investigator
      TOMODA Hiroshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      The Kitasato Institute
  •  海洋糸状菌、海綿、ホヤを対象としたがん化学療法剤の探索

    • Principal Investigator
      浪越 通夫
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      東京水産大学
  •  白血病細胞のアポトーシス誘導ならびに浸潤阻止のための制御技術と天然薬物の開発

    • Principal Investigator
      片桐 拓也
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kitasato Institute
  •  Studies on fungal pyripyropenes, potent inhibitors of cholesterol metabolism

    • Principal Investigator
      OMURA Satoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      The Kitasato Institute
  •  Studies on the cellular functions of lipid-modified proteins

    • Principal Investigator
      OHMURA Satoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The Kitasato Institute
  •  Basic study for analysis and application of bio-factor which regulate transfer of cholresterol in vivo.

    • Principal Investigator
      INOUE Keizo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      University of Tokyo
  •  Inhibition of foam cell formation : Application to the discovery of novel antiatherosclerotic agents

    • Principal Investigator
      OMURA Satoshi
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The Kitasato Institute

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book Patent

  • [Book] 動脈硬化Update20082009

    • Author(s)
      供田洋 (分担執筆)
    • Publisher
      ライフサイエンス出版
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Screening for microbial potentiators of neutral lipid degradation in CHO-K1 cells2022

    • Author(s)
      Nur Elyza Aiman Azizah、Kobayashi Keisuke、Ohte Satoshi、Tomoda Hiroshi、Ohshiro Taichi
    • Journal Title

      Drug Discoveries & Therapeutics

      Volume: 16 Issue: 6 Pages: 273-279

    • DOI

      10.5582/ddt.2022.01087

    • ISSN
      1881-7831, 1881-784X
    • Year and Date
      2022-12-25
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18KK0219, KAKENHI-PROJECT-19K16320
  • [Journal Article] Inhibition of cholesteryl ester synthesis by polyacetylenes from Atractylodes rhizome.2020

    • Author(s)
      Nur EAA, Ohshiro T, Kobayashi K, Wu J, Wahyudin E, Zhang H, Hayashi F, Kawagishi H, Tomoda H.
    • Journal Title

      Bioorg Med Chem Lett

      Volume: 30 Issue: 7 Pages: 126997-126997

    • DOI

      10.1016/j.bmcl.2020.126997

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06555, KAKENHI-PLANNED-17H06402, KAKENHI-PROJECT-18K05345, KAKENHI-PROJECT-18KK0219
  • [Journal Article] New Terpendole Congeners, Inhibitors of Sterol O-Acyltransferase, Produced by Volutella citrinella BF-04402020

    • Author(s)
      Nur Elyza Aiman Azizah、Kobayashi Keisuke、Amagai Ai、Ohshiro Taichi、Tomoda Hiroshi
    • Journal Title

      Molecules

      Volume: 25 Issue: 13 Pages: 3079-3079

    • DOI

      10.3390/molecules25133079

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16320, KAKENHI-PROJECT-18KK0219, KAKENHI-PROJECT-18K06555
  • [Journal Article] MS network-based screening for new antibiotics discovery2019

    • Author(s)
      Koyama N & Tomoda H
    • Journal Title

      J Antibiot

      Volume: 72 Issue: 1 Pages: 54-56

    • DOI

      10.1038/s41429-018-0109-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K05464, KAKENHI-PROJECT-26253009
  • [Journal Article] Helvamide, a new inhibitor of sterol O-acyltransferase produced by the fungus Aspergillus nidulans BF-0142.2019

    • Author(s)
      Fukuda T, Furukawa T, Kobayashi K, Nagai K, Uchida R, Tomoda H.
    • Journal Title

      J Antibiot

      Volume: 72 Issue: 1 Pages: 8-14

    • DOI

      10.1038/s41429-018-0101-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Journal Article] Simpotentin, a new potentiator of amphotericin B activity against Candida albicans, produced by Simplicillium minatense FKI-4981.2019

    • Author(s)
      Uchida R, Kondo A, Yagi A, Nonaka K, Masuma R, Kobayashi K, Tomoda H
    • Journal Title

      J Antibiot

      Volume: 72 Issue: 3 Pages: 134-140

    • DOI

      10.1038/s41429-018-0128-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16H05095
  • [Journal Article] Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307.2018

    • Author(s)
      Ohshiro T, Seki R, Fukuda T, Uchida R, Tomoda H.
    • Journal Title

      J Antibiot

      Volume: 71 Pages: 1000-1007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Journal Article] Discovery of a Fungal Multicopper Oxidase That Catalyzes the Regioselective Coupling of a Tricyclic Naphthopyranone To Produce Atropisomers2018

    • Author(s)
      Mio Kawaguchi, Taichi Ohshiro, Masayuki Toyoda, Satoshi Ohte, Junji Inokoshi, Isao Fujii, Hiroshi Tomoda
    • Journal Title

      Angwandte Chemie Int. Edt.

      Volume: 57 Issue: 18 Pages: 5115-5119

    • DOI

      10.1002/anie.201800415

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05449, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-17H03995, KAKENHI-PROJECT-16K18900
  • [Journal Article] Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp.2018

    • Author(s)
      Kapojos MM, Abdjul DB, Yamazaki H, Ohshiro T, Rotinsulu H, Wewengkang DS, Sumilat DA, Tomoda H, Namikoshi M, Uchida R.
    • Journal Title

      Bioorg Med Chem Lett.

      Volume: 28 Issue: 10 Pages: 1911-1914

    • DOI

      10.1016/j.bmcl.2018.03.077

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900, KAKENHI-PROJECT-16K21310, KAKENHI-PROJECT-17KK0173
  • [Journal Article] A Mixture of Atropisomers Enhances Neutral Lipid Degradation in Mammalian Cells with Autophagy Induction.2018

    • Author(s)
      Kobayashi K, Ohte S, Ohshiro T, Ugaki N, Tomoda H.
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 12099-12099

    • DOI

      10.1038/s41598-018-30679-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06555, KAKENHI-PROJECT-26253009
  • [Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018

    • Author(s)
      Karasawa Tadayoshi、Kawashima Akira、Usui-Kawanishi Fumitake、Watanabe Sachiko、Kimura Hiroaki、Kamata Ryo、Shirasuna Koumei、Koyama Yutaro、Sato-Tomita Ayana、Matsuzaka Takashi、Tomoda Hiroshi、Park Sam-Yong、Shibayama Naoya、Shimano Hitoshi、Kasahara Tadashi、Takahashi Masafumi
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology

      Volume: 38 Issue: 4 Pages: 744-756

    • DOI

      10.1161/atvbaha.117.310581

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-17K09889, KAKENHI-PUBLICLY-16H01395, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16K09808, KAKENHI-INTERNATIONAL-15K21719
  • [Journal Article] Design and Synthesis of A-Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors2018

    • Author(s)
      Ohtawa Masaki、Arima Shiho、Ichida Naoki、Terayama Tomiaki、Ohno Hironao、Yamazaki Takaya、Ohshiro Taichi、Sato Noriko、Omura Satoshi、Tomoda Hiroshi、Nagamitsu Tohru
    • Journal Title

      ChemMedChem

      Volume: 13 Issue: 5 Pages: 411-421

    • DOI

      10.1002/cmdc.201700645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08370, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900
  • [Journal Article] Variation in the activity of distinct cytochalasins as autophagy inhibitiors in human lung A549 cells.2017

    • Author(s)
      Takanezawa Y, Nakamura R, Sone Y, Uraguchi S, Kobayashi K, Tomoda H, Kiyono M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 494 Issue: 3-4 Pages: 641-647

    • DOI

      10.1016/j.bbrc.2017.10.135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K15381
  • [Journal Article] Pseudopyronine B, an inhibitor of sterol O-acyltransferase, produced by Pseudomonas sp. BYK11209.2017

    • Author(s)
      Suzuki A, Fukuda T, Kobayashi K, Ohshiro T, Tomoda H.
    • Journal Title

      J Antibiot,

      Volume: 70 Issue: 1 Pages: 798-805

    • DOI

      10.1038/ja.2016.46

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15J12265, KAKENHI-PROJECT-16K18900, KAKENHI-PROJECT-15K07417
  • [Journal Article] Biseokeaniamides A, B, and C, Sterol O-Acyltransferase Inhibitors from an Okeania sp. Marine Cyanobacterium.2017

    • Author(s)
      Iwasaki A, Tadenuma T, Sumimoto S, Ohshiro T, Ozaki K, Kobayashi K, Teruya T, Tomoda H, Suenaga K.
    • Journal Title

      J Nat Prod.

      Volume: 80 Issue: 4 Pages: 1161-1166

    • DOI

      10.1021/acs.jnatprod.7b00137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900, KAKENHI-PROJECT-16H03285, KAKENHI-PROJECT-15K01803
  • [Journal Article] Scopranones with Two Atypical Scooplike Moieties Produced by Streptomyces sp. BYK-110382017

    • Author(s)
      Uchida Ryuji、Lee Daiki、Suwa Ibuki、Ohtawa Masaki、Watanabe Nozomu、Demachi Ayumu、Ohte Satoshi、Katagiri Takenobu、Nagamitsu Tohru、Tomoda Hiroshi
    • Journal Title

      Organic Letters

      Volume: 19 Issue: 21 Pages: 5980-5983

    • DOI

      10.1021/acs.orglett.7b03003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15134, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-17H04317
  • [Journal Article] Selective inhibition of sterolO-acyltransferase 1 isozyme by beauveriolide III in intact cells2017

    • Author(s)
      T. Ohshiro, K. Kobayashi, M. Ohba, D. Matsuda, L. L. Rudel, T. Takahashi, T. Doi, H. Tomoda
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 4163-4163

    • DOI

      10.1038/s41598-017-04177-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05837, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900
  • [Journal Article] 7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007.2016

    • Author(s)
      Uchida R, Nakajyo K, Kobayashi K, Ohshiro T, Terahara T, Imada C, Tomoda H.
    • Journal Title

      J Antibiot

      Volume: 69 Issue: 8 Pages: 647-651

    • DOI

      10.1038/ja.2016.27

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900
  • [Journal Article] Design, Synthesis, and Biological Evaluation of Beauveriolide Analogues Bearing Photoreactive Amino Acids2016

    • Author(s)
      Masuda Y, Aoyama K, Yoshida M, Kobayashi K, Ohshiro T, Tomoda H, Doi T.
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 64 Issue: 7 Pages: 754-765

    • DOI

      10.1248/cpb.c16-00095

    • NAID

      130005160040

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-26282208, KAKENHI-PROJECT-26850068, KAKENHI-PROJECT-16K07707, KAKENHI-PROJECT-16K18900
  • [Journal Article] Discovery of SOAT2 Inhibitors from Synthetic Small Molecules2016

    • Author(s)
      Kobayashi, K.; Ohshiro, T.; Tomoda, H.; Yin, F.; Cui, H.-L.; Chouthaiwale, P. V.; Tanaka, F.
    • Journal Title

      Bioorg. Med. Chem Lett.

      Volume: 26 Issue: 24 Pages: 5899-5901

    • DOI

      10.1016/j.bmcl.2016.11.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-26105757, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15J12265, KAKENHI-PROJECT-16K18900
  • [Journal Article] PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice.2015

    • Author(s)
      Lopez AM, Chuang JC, Posey KS, Ohshiro T, Tomoda H, Rudel LL, Turley SD.
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 355 Issue: 2 Pages: 159-67

    • DOI

      10.1124/jpet.115.227207

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Journal Article] Acyltransferase inhibitors: a patent review (2010-present).2015

    • Author(s)
      Ohshiro T, Tomoda H.
    • Journal Title

      Expert Opin Ther Pat

      Volume: 25 Issue: 2 Pages: 145-158

    • DOI

      10.1517/13543776.2014.989833

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Journal Article] Clonoamide, a new inhibitor of sterol O-acyltransferase, produced by Clonostachys sp. BF-0131.2015

    • Author(s)
      Kobayashi K, Tsukasaki N, Uchida R, Yamaguchi Y, Tomoda H.
    • Journal Title

      J Antibiot

      Volume: 68 Issue: 10 Pages: 615-619

    • DOI

      10.1038/ja.2015.37

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Journal Article] New pyripyropene derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse model.2015

    • Author(s)
      Ohshiro, T.; Ohtawa, M.; Nagamitsu, T.; Matsuda, D.; Yagyu, H.; Davis, M. A.; Rudel, L. L.; Ishibashi, S.; Tomoda, H.
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: 355 Issue: 2 Pages: 299-309

    • DOI

      10.1124/jpet.115.227348

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460152, KAKENHI-PROJECT-25293213, KAKENHI-PROJECT-26253009
  • [Journal Article] Clonoamide, a new inhibitor of sterol O-acyltransferase, produced by Clonostachys sp. BF-0131.2015

    • Author(s)
      Kobayashi K., Tsukasaki N., Uchida R., Yamaguchi Y., Tomoda H.
    • Journal Title

      J. Antibiot.

      Volume: 68 Issue: 10 Pages: 615-619

    • DOI

      10.1038/ja.2015.38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15J12265, KAKENHI-PROJECT-26253009
  • [Journal Article] Bafilomycin L, a new inhibitor of cholestesryl ester synthesis in mammalian cells, produced by marine-derived Streptomyces sp. OPMA00072.2015

    • Author(s)
      Kobayashi K., Fukuda T., Usui T., Kurihara Y., Kanamoto A., Tomoda H.
    • Journal Title

      J. Antibiot.

      Volume: 68 Issue: 2 Pages: 126-132

    • DOI

      10.1038/ja.2014.100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15J12265, KAKENHI-PROJECT-26253009
  • [Journal Article] In vitro metabolism of pyripyropene A and ACAT inhibitory activity of its metabolites.2015

    • Author(s)
      Ohshiro, T.; Matsuda, D.; Ohtawa, M.; Yamazaki, H.; Nagamitsu. T.; Tomoda, H.
    • Journal Title

      J. Antibiot. 2015, 25, 313-316.

      Volume: 68 Issue: 1 Pages: 27-34

    • DOI

      10.1038/ja.2014.91

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460152, KAKENHI-PROJECT-26460013, KAKENHI-PROJECT-26253009
  • [Journal Article] Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages.2014

    • Author(s)
      Sekiya M, Yamamuro D, Ohshiro T, Honda A, Takahashi M, Kumagai M, Sakai K, Nagashima S, Tomoda H, Igarashi M, Okazaki H, Yagyu H, Osuga J, Ishibashi S.
    • Journal Title

      J Lipid Res

      Volume: 55 Issue: 10 Pages: 2082-2092

    • DOI

      10.1194/jlr.m050864

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293213, KAKENHI-PROJECT-26870533, KAKENHI-PROJECT-26253009
  • [Journal Article] Mode of Action of Microbial Anti-MRSA Agents2012

    • Author(s)
      Tomoda H.
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 132 Issue: 1 Pages: 37-44

    • DOI

      10.1248/yakushi.132.37

    • NAID

      130001871960

    • ISSN
      0031-6903, 1347-5231
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Journal Article] Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B01712012

    • Author(s)
      Inokoshi J, Matsuhama M, Miyake M, Ikeda H, Tomoda H.
    • Journal Title

      Appl Microbiol Biotechnol

      Volume: (In press) Issue: 2 Pages: 451-460

    • DOI

      10.1007/s00253-012-3973-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310146, KAKENHI-PLANNED-22108006
  • [Journal Article] Synthesis and antimycobacterial activity of calpinactam derivatives2012

    • Author(s)
      Kenichiro Nagai, Nobuhiro Koyama, Noriko Sato, Chisato Yanagisawa, Hiroshi Tomoda
    • Journal Title

      Bioorg.Med.Chem.Lett

      Volume: 22 Pages: 7739-7741

    • URL

      http://dx.doi.org/10.1016/j.bmcl.2012.09.069

    • Data Source
      KAKENHI-PROJECT-23790019
  • [Journal Article] Recent Advance in Research of New Anti-Infectious Agents—Discovery Chemical Biology and Development—2012

    • Author(s)
      Tomoda H, et al
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 132 Issue: 1 Pages: 35-36

    • DOI

      10.1248/yakushi.132.35

    • NAID

      130001871959

    • ISSN
      0031-6903, 1347-5231
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Journal Article] Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-12009

    • Author(s)
      Yamazaki H, Omura S, Tomoda H
    • Journal Title

      II. Structure elucidation. J. Antibiot 62

      Pages: 207-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Pentacecilides new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1 : I. Taxonomy, fermentation, isolation and biological properties2009

    • Author(s)
      Yamazaki H, Kobayashi K, Matsuda D, Nonaka K, Masuma R, Omura S, Tomoda H.
    • Journal Title

      J. Antibiot 62

      Pages: 195-200

    • NAID

      10030635010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Total synthesis of amidepsine B and revision of its absolute configuration2009

    • Author(s)
      Nagamitsu T, Marumoto K, Nagayasu A, Fukuda T, Arima S, Uchida R, Ohshiro T, Harigaya Y, Tomoda H, Omura S.
    • Journal Title

      J. Antibiot 62

      Pages: 69-74

    • NAID

      10030634591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] The selectivity of beauveriolide derivatives in inhibition toward the two isozymes of acyl-CoA2009

    • Author(s)
      Ohshiro T, Matsuda D, Nagai K, Doi T, Sunazuka T, Takahashi T, Rudel LL, Omura S, Tomoda H.
    • Journal Title

      cholesterol acyltransferase . Chem. Pharm. Bull 57

      Pages: 377-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Expression of two human acyl-CoA : diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes2009

    • Author(s)
      Inokoshi J, Kawamoto K, Takagi Y, Matsuhama M, Omura S, Tomoda H.
    • Journal Title

      J. Antibiot 62

      Pages: 51-54

    • NAID

      10030634523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Discovery and combinatorial synthesis of fungal metabolites beauveriolides, novel antiatherosclerotic agents.2008

    • Author(s)
      Tomoda H, Doi T.
    • Journal Title

      Acc. Chem. Res. 41

      Pages: 32-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Synthesis and biological evaluation of a focused library of beauveriolides2008

    • Author(s)
      Nagai K, Doi T, Ohshiro T, Sunazuka T, Tomoda H, Takahashi T, Omura S.
    • Journal Title

      Bioorg. Med. Chem. Lett. 18

      Pages: 4397-4400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Molecular target of piperine in the inhibition of lipid droplet accumulation in macrophages2008

    • Author(s)
      Matsuda D, Ohte S, Ohshiro T, Jiang W,Rudel L, Hong B, Si S, Tomoda H.
    • Journal Title

      Biol. Pharm. Bull. 31

      Pages: 1063-1066

    • NAID

      110006684316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA : cholesterol acyltransferase 2 isozyme2008

    • Author(s)
      Ohshiro T, Ohte S, Matsuda D, Ohtawa M, Nagamitsu T, Sunazuka T, Harigaya Y, Rudel LL, Omura S, Tomoda H.
    • Journal Title

      J. Antibiot 61

      Pages: 503-508

    • NAID

      10021928313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Inhibition of lipid droplet accumulation in mouse macrophages by stemphone derivatives.2008

    • Author(s)
      Koyama N, Kobayashi K, Yamazaki H, Tomoda H.
    • Journal Title

      J. Antibiot 61

      Pages: 509-514

    • NAID

      10021928336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Selective inhibition of acyl-CoA : cholesterol acyltransferase 2 isozyme by flavasperone and sterigmatocystin from Aspergillus species2008

    • Author(s)
      Sakai K, Ohte S, Ohshiro T, Matsuda D, Masuma R, Rudel LL, Tomoda H.
    • Journal Title

      J. Antibiot 61

      Pages: 568-572

    • NAID

      10022599820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Cholesterol synthesis inhibition elicits an integrated molecular response in human livers including decreased ACAT22008

    • Author(s)
      Parini P, Gustafsson U, Davis MA, Larsson L, Einarsson C, Wilson M, Rudling M, Tomoda H, Omura S, Sahlin S, Angelin B, Rudel LL, Eriksson M.
    • Journal Title

      Arterioscler. Thromb. Vasc. Biol. 28

      Pages: 1200-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Identification of the interaction site within acyl-CoA : cholesterol acyltransferase 2 for the isoform-specific inhibitor pyripyropene A.2008

    • Author(s)
      Das A, Davis MA, Tomoda H, Omura S, Rudel LL.
    • Journal Title

      J. Biol. Chem. 18

      Pages: 10453-10460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Potential therapeutics for obesity and atherosclerosis : inhibitors of neutral lipid metabolism from microorganisms2007

    • Author(s)
      Tomoda H, Omura S.
    • Journal Title

      Pharmacol. Ther 115

      Pages: 375-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Discovery and combinatorial synthesis of fungal metabolitebeauveriolides, novel antiatherosclerotic agents2007

    • Author(s)
      Tomoda, H., et. al.
    • Journal Title

      Ace. Chem. Res. 41

      Pages: 32-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Journal Article] DGAT inhibitors for obesity2007

    • Author(s)
      Matsuda D, Tomoda H.
    • Journal Title

      Curr. Opin. Investig. Drugs. 8

      Pages: 836-841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Potential therapeutics for obesity and atherosclerosis:inhibitors of neutral lipid metabolism from microorganisnis2007

    • Author(s)
      Tomoda, H., et. al.
    • Journal Title

      Pharmacol. Ther. 115

      Pages: 375-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Journal Article] Fungal isobisvertional, a new inhibitor of lipid droplet accumulation in mouse macrophages2007

    • Author(s)
      Koyama N, Ohshiro T, Tomoda H, Omura S.
    • Journal Title

      Org. Lett. 9

      Pages: 425-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] DGAT inhibitors of obesity2007

    • Author(s)
      Matsuda, D.&Tomoda, H.
    • Journal Title

      Curr. Opin Investig. Drugs 8

      Pages: 836-841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Potential therapeutics for obesity and atherosclerosis:inhibitors of neutral lipid metabolism from microorganisms2007

    • Author(s)
      Tomoda, H.&Omura, S.
    • Journal Title

      Pharmacol.Ther. 115

      Pages: 375-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Selectivity of microbial acyl-CoA : cholesterol acyltransferase inhibitors toward isozymes.2007

    • Author(s)
      Ohshiro T, Rudel LL, Omura S, Tomoda H.
    • Journal Title

      J. Antibiot 60

      Pages: 43-51

    • NAID

      10018493742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] Discovery and combinatorial synthesis of fungal metabolite beauveriolides, novel antiatherosclerotic agents2007

    • Author(s)
      Tomoda, H.&Doi, T.
    • Journal Title

      Acc.Chem.Res. 41

      Pages: 32-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] 脂質代謝を制御する機能分子の開拓2006

    • Author(s)
      供田 洋
    • Journal Title

      化学工業 57 (10)

      Pages: 734-739

    • Data Source
      KAKENHI-PROJECT-16073215
  • [Journal Article] 脂質代謝を制御する機能分子の開拓2006

    • Author(s)
      供田 洋
    • Journal Title

      化学工業 57(10)

      Pages: 734-739

    • Data Source
      KAKENHI-PROJECT-18390008
  • [Journal Article] 創薬を目指した微生物由来脂質代謝阻害剤2005

    • Author(s)
      供田 洋
    • Journal Title

      バイオサイエンスとインダストリー 63(4)

      Pages: 16-22

    • NAID

      10015464855

    • Data Source
      KAKENHI-PROJECT-16073215
  • [Journal Article] Binding site for fungal β-lactone hymeglusin on cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase.2004

    • Author(s)
      Tomoda, H. et al.
    • Journal Title

      Biochim.Biophys.Acta 1636

      Pages: 22-28

    • Data Source
      KAKENHI-PROJECT-16073215
  • [Journal Article] 中性脂質合成酵素とそれを制御する微生物由来低分子化合物2004

    • Author(s)
      供田 洋
    • Journal Title

      ファルマシア 40

      Pages: 714-718

    • Data Source
      KAKENHI-PROJECT-16073215
  • [Patent] ステロールO-アシルトランスフェラーゼ2(SOAT2)阻害活性を有する新規化合物及びその製造方法2018

    • Inventor(s)
      供田洋、大城太一
    • Industrial Property Rights Holder
      供田洋、大城太一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-231046
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Patent] ステロールO-アシルトランスフェラーゼ2(SOAT2)阻害活性を有する新規化合物及びその製造方法2017

    • Inventor(s)
      供田洋、福田隆志、大城太一
    • Industrial Property Rights Holder
      北里大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-005260
    • Filing Date
      2017-01-16
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Patent] MRSA産生黄色色素の生成阻害能を示す新規化合物とその製造方法2011

    • Inventor(s)
      供田洋, ら
    • Industrial Property Rights Holder
      北里大学
    • Industrial Property Number
      2011-156720
    • Filing Date
      2011-07-15
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Patent] MRSA産生黄色色素の生成阻害能を示す新規化合物とその用途2011

    • Inventor(s)
      供田洋、長光亨、福田隆志、小山信裕
    • Industrial Property Rights Holder
      学校法人北里研究所
    • Filing Date
      2011-10-12
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Patent] 抗真菌剤の活性増強作用を有する新規物質およびその製造方法と用途2011

    • Inventor(s)
      供田洋, 内田龍児, 野中健一, 増間碌郎, 大村智
    • Industrial Property Rights Holder
      学校法人 北里研究所
    • Industrial Property Number
      2011-041894
    • Filing Date
      2011-02-28
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Patent] MRSA産生黄色色素の生成阻害能を示す新規化合物とその製造方法2011

    • Inventor(s)
      供田洋、福田隆志、小山信裕
    • Industrial Property Rights Holder
      学校法人北里研究所
    • Filing Date
      2011-07-15
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Patent] MRSA産生黄色色素の生成阻害能を示す新規化合物とその用途2011

    • Inventor(s)
      供田洋, ら
    • Industrial Property Rights Holder
      北里大学
    • Industrial Property Number
      2011-224968
    • Filing Date
      2011-10-12
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Patent] 新規FKI-3864物質およびその製造方法2008

    • Inventor(s)
      供田 洋, 内田龍児, 増間碌郎, 大村智
    • Industrial Property Rights Holder
      北里学園
    • Filing Date
      2008-02-13
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Patent] 新規FKI・1746-1およびFKI-1746・2物質並びにそれらの製造方法2008

    • Inventor(s)
      供田 洋, 小山信裕, 増間碌郎, 大村智
    • Industrial Property Rights Holder
      北里学園
    • Filing Date
      2008-02-05
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Patent] 新規FKI・3368物質およびその製造方法2007

    • Inventor(s)
      供田 洋, 猪腰淳嗣, 増間縁郎, 大村智
    • Industrial Property Rights Holder
      北里学園
    • Filing Date
      2007-09-14
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Patent] FKI-1938瀕およびその製造法2004

    • Inventor(s)
      供田洋, 増間碌郎, 大村智
    • Industrial Property Rights Holder
      社団法人北里研究所
    • Filing Date
      2004-10-28
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Patent] 新規K03-0132物質およびその製造法2004

    • Inventor(s)
      供田洋, 高橋洋子, 大村智
    • Industrial Property Rights Holder
      社団法人北里研究所
    • Filing Date
      2004-12-22
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Patent] 新規FKI-1840物質及びその製造法2004

    • Inventor(s)
      供田洋, 増間碌郎, 大村智
    • Industrial Property Rights Holder
      社団法人北里研究所
    • Filing Date
      2004-01-12
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Presentation] Fungal srimane sesquiterpenoids from BF-1613 strain as sterol O-acyltransferase (SOAT) inhibitors2024

    • Author(s)
      Nur Elyza, Keisuke Kobayashi, Hiroshi Tomoda, Taichi Ohshiro
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] Searching for Lipid Metabolism Regulators in Mammalian Cells from Microorganism2023

    • Author(s)
      Elyza Aiman Azizah Nur, Keisuke Kobayashi, Satoshi Ohte, Hiroshi Tomoda, and Taichi Ohshiro
    • Organizer
      13th ISISM, 10th ISIBio, and 20th ACM meeting
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] 真菌Volutella citrinella BF-0440株が生産する新規テルペンドール類に関する研究2022

    • Author(s)
      Elyza Nur、小林 啓介、大城 太一、供田 洋
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] 真菌 Volutella citrinella BF-0440 株が生産する新規 voluhemin 類と terpendole 類に関する研究2022

    • Author(s)
      Nur Elyza、小林 啓介、供田 洋、大城 太一
    • Organizer
      第12回AKPS北里化学シンポジウム(優秀ポスター賞)
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] Discovery of anti-mycobacterial compounds from microorganisms2019

    • Author(s)
      Hiroshi Tomoda
    • Organizer
      International Seminar on Bioscience and Drug Discovery
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] SOAT2 選択的阻害活性を有する oleanane 型トリテルぺン化合物類に関する研究2019

    • Author(s)
      大城 太一, 関 怜子, 山崎 寛之, 大手 聡, Abdjul DELFY B., 内田 龍児, 浪越 通夫, 供田 洋
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Inhibition of cholesteryl ester accumulation by polyacetylenes isolated from Atractylodes rhizome2019

    • Author(s)
      Elyza Nur, Taichi Ohshiro, Jing Wu, Hirokazu Kawagishi, Hiroshi Tomoda
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] ビャクジュツ由来ポリアセチレン化合物の細胞内コレステリルエステル蓄積阻害作用2019

    • Author(s)
      Elyza Nur, Taichi Ohshiro, Jing Wu, Hirokazu Kawagishi, Hiroshi Tomoda
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 温泉土壌由来真菌 BF-0026 株が生産する新規 SOAT 阻害剤に関する研究2019

    • Author(s)
      金子 紗也, 大城 太一, 関 怜子, 細田 莞爾, 供田 洋
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 真菌 BF-0440 株が生産する新規 SOAT2 選択的阻害剤に関する研究2019

    • Author(s)
      森田 遥, Elyza NUR, 大城 太一, 細田 莞爾, 供田 洋
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] New Anti-Mycobacterial Compounds from Microorganisms.2018

    • Author(s)
      Hiroshi Tomoda
    • Organizer
      BIT's 7th Annual World Congress of Infectious Diseases 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0219
  • [Presentation] ナフトピラノン化合物を 位置選択的に二量体化する 真菌由来カップリング酵素MCEの発見2018

    • Author(s)
      大城 太一、川口 未央、豊田 雅幸、大手 聡、猪腰 淳嗣、藤井 勲、供田 洋
    • Organizer
      第 60 回 天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 動物細胞内中性脂質蓄積を指標とした新規創薬素材の探索2018

    • Author(s)
      供田 洋
    • Organizer
      第50回 日本臨床分子形態学会総会・学会集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Study of PRD125, a SOAT2-Selective Inhibitor, in Atherogenic Mouse Model.2018

    • Author(s)
      Ohshiro T,Sawyer J, Matthew A Davis, Ohtawa M, Nagamitsu T, Lawrence L Rudel, Tomoda H.
    • Organizer
      AHA Scientific Session 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 真菌由来の新規 SOAT 阻害剤 celludinone A の立体化学に関する研究2018

    • Author(s)
      関 怜子、大城太一、供田 洋
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] SOAT アイソザイム選択的阻害剤の展望2018

    • Author(s)
      大城 太一、小林 啓介、大多和 正樹、 長光 亨、 供田 洋
    • Organizer
      第 60 回 日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] モナピノン二量体化酵素MCEに関する酵素学的研究2018

    • Author(s)
      大城 太一、豊田 雅幸、大手 聡、供田 洋
    • Organizer
      第20回マリンバイオテクノロジー学会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] SOAT2選択的阻害剤ピリピロペンAの新戦略2018

    • Author(s)
      大城 太一、供田 洋
    • Organizer
      Biotech2018 第15回アカデミックフォーラム
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] ピリピロペン誘導体の抗動脈硬化作用 (II)2018

    • Author(s)
      大城太一、大多和正樹、長光 亨、Lawrence RUDEL、供田 洋
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 脂肪滴分解を促進するダイナピノンの研究2018

    • Author(s)
      供田 洋
    • Organizer
      新学術領域研究「化学コミュニケーションのフロンティア」京都大学生理化学研究ユニットシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 中性脂質蓄積阻害剤 dinapinone A の結合タンパク質の解析2018

    • Author(s)
      奥畑颯眞、小林啓介、供田 洋
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 軸異性を有する真菌由来化合物ダイナピノンが示す脂肪滴分解促進活性の作用機序解析2017

    • Author(s)
      小林 啓介、大城太一、大手 聡、供田 洋
    • Organizer
      第59回 日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Drug discovery of inhibitors of sterol O-acyltransferase from microorganisms.2017

    • Author(s)
      Tomoda H
    • Organizer
      2nd World Congress & Expo on Pharmaceutics & Drug Delivery Systems
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2017-03-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 真菌由来化合物 dinapinone 類が示す中性脂質蓄積阻害活性の作用機序解析2017

    • Author(s)
      小林啓介、大城太一、小山信裕、大手聡、供田 洋
    • Organizer
      平成29年度生命科学系合同年次大会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Dinapinone A による脂質分解促進活性に関する研究2017

    • Author(s)
      小林啓介、大城太一、供田 洋
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台市
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] SOAT2 選択的阻害剤は脂肪性肝疾患に有効か?2017

    • Author(s)
      大城太一、大多和正樹 、長光 亨 、Rudel Lawrence L.、石橋 俊、供田 洋
    • Organizer
      第59回 日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 位置選択的モナピノン二量体化酵素 MCE の基質特異性に関する研究2017

    • Author(s)
      大城太一、豊田雅幸 、 川口未央 、 供田 洋
    • Organizer
      平成29年度生命科学系合同年次大会
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] ボーベリオライド誘導体の抗動脈硬化作用2017

    • Author(s)
      大城太一、伊牟田聡、土黒一郎、高橋孝志、土井隆行、石橋俊、供田洋
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台市
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 土壌由来真菌が生産する新規 SOAT2 選択的阻害剤に関する研究2017

    • Author(s)
      関怜子、大城太一、福田隆志、内田龍児、供田 洋
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台市
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Monapinone 二量体化酵素による新規 dinapinone 類の酵素学的解析2017

    • Author(s)
      豊田雅幸、大城太一、出町歩、小林啓介、川口未央、供田 洋
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台市
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26670050
  • [Presentation] なぜ beauveriolide III はインタクト細胞で sterol O-acyltransferase 1選択的阻害活性を示すのか?2016

    • Author(s)
      小林啓介、大城太一、高橋孝志、土井隆行、供田 洋
    • Organizer
      第21回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      千葉市
    • Year and Date
      2016-10-27
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 真菌由来 beauveriolide Ⅲ の SOAT アイソザイム阻害活性機構に関する研究2016

    • Author(s)
      小林啓介、大城太一、供田洋
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] ピリピロペン誘導体の抗動脈硬化作用2016

    • Author(s)
      大城太一、大多和正樹、長光亨、松田大介、野牛宏晃、Matthew DAVIS、Lawrence RUDEL、石橋俊、供田洋
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 真菌 Talaromyces pinophilus FKI-3864 由来の monapinone カップリング酵素の異種発現系の構築2016

    • Author(s)
      出町歩、石掛太樹、猪腰淳嗣、藤井勲、供田洋
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26670050
  • [Presentation] 海洋放線菌 Streptomyces sp. KM10-4 株が生産するトリグリセリド蓄積阻害活性物質に関する研究2016

    • Author(s)
      鈴木あいか、福田隆志、小林啓介、大城太一、瀧 誠二、山田勝久、寺原 猛、今田千秋、供田 洋
    • Organizer
      第18回マリンバイオテクノロジー学会大会
    • Place of Presentation
      函館市
    • Year and Date
      2016-05-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 細胞内の脂肪滴分解を促進する真菌由来化合物 dinapinone A の作用機序解析2016

    • Author(s)
      小林啓介、大城太一、供田 洋
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台市
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] A novel inhibitor of neutral lipid synthesis produced by hot spring-derived fungus Aspergillus sp. BF142.2016

    • Author(s)
      Furukawa T, Fukuda T, Uchida R, Kobayashi K, Tomoda H.
    • Organizer
      The 8th Japan-Korea Chemical Biology Symposium
    • Place of Presentation
      Okinawa (Pacific hotel Okinawa)
    • Year and Date
      2016-01-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] SOAT2選択的阻害剤ピリピロペン誘導体の抗動脈硬化作用2016

    • Author(s)
      大城太一、大多和正樹、長光 亨、Lawrence L. Rudel、供田 洋
    • Organizer
      第58回日本脂質生化学会
    • Place of Presentation
      秋田市
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 土壌由来真菌BF-0307株が産生する中性脂質蓄積阻害物質に関する研究2016

    • Author(s)
      関怜子、小林啓介、大城太一、福田隆志、内田龍児、供田洋
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 微生物由来脂質代謝阻害剤からの創薬への挑戦2016

    • Author(s)
      供田 洋
    • Organizer
      第54回ヒューマンサイエンス・バイオインターフェース講演会
    • Place of Presentation
      東京
    • Year and Date
      2016-05-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Monapinone 二量体化酵素の精製方法の改良2016

    • Author(s)
      豊田雅幸、石掛太樹、猪腰淳嗣、供田洋
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-26670050
  • [Presentation] Sterol O-acyltransferase アイソザイムに対する beauveriolide IIIの阻害機構の解明2016

    • Author(s)
      小林啓介、大城太一、供田 洋
    • Organizer
      第58回日本脂質生化学会
    • Place of Presentation
      秋田市
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Selective inhibition of beauveriolide III against SOAT isozymes.2016

    • Author(s)
      Kobayashi K, Ohshiro T, Rudel LL, Tomoda H.
    • Organizer
      The 8th Japan-Korea Chemical Biology Symposium
    • Place of Presentation
      Okinawa (Pacific hotel Okinawa)
    • Year and Date
      2016-01-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 微生物由来機能分子のケミカルバイオロジー2015

    • Author(s)
      供田洋
    • Organizer
      高磁場・高感度NMR利活用促進のための天然物関連シンポジウム2015
    • Place of Presentation
      横浜(理化学研究所横浜キャンパス)
    • Year and Date
      2015-08-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670050
  • [Presentation] 海洋由来真菌 Aspergillus unguis NKM - 007株が生産する新規 depsidoneに関する研究2015

    • Author(s)
      内田龍児、中條賢人、小林啓介、寺原 猛、今田千秋、供田 洋
    • Organizer
      第17回マリンバイオテクノロジー学会大会
    • Place of Presentation
      東京(東京海洋大学)
    • Year and Date
      2015-05-31
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 海洋由来放線菌が生産する sterol-O-acyltransferase 阻害活性を示す diketopiperazine 化合物に関する研究2015

    • Author(s)
      小林啓介、福田隆志、寺原 猛、春成円十朗、今田千秋、供田 洋
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸(神戸学院大学)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] セルレニン生産菌の脂肪酸合成酵素遺伝子の解析2015

    • Author(s)
      出町 歩、猪腰淳嗣、藤井 勲、供田 洋
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸(神戸学院大学)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 微生物資源からの創薬研究2015

    • Author(s)
      供田 洋
    • Organizer
      第23回クリニカルファーマシーシンポジウム/医療薬学フォーラム
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-07-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 土壌細菌 BYK11209 株が生産する新規中性脂質生成阻害物質に関する研究2015

    • Author(s)
      鈴木あいか、小林啓介、福田隆志、内田龍児、供田 洋
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸(神戸学院大学)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 海洋由来真菌 Aspergillus sp. NKM-007 株が生産する新規 depsidone に関する研究2015

    • Author(s)
      中條賢人、内田龍児、小林啓介、寺原 猛、今田千秋、供田 洋
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸(神戸学院大学)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 温泉由来真菌 BF142 株が産生する新規中性脂質生成阻害物質に関する研究2015

    • Author(s)
      古川茶勲、福田隆志、小林啓介、内田龍児、供田 洋
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸(神戸学院大学)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Microbial inhibitors of lipid metabolism---from discovery to challenge for development---2015

    • Author(s)
      Tomoda H.
    • Organizer
      Liver Academy at Karolinska
    • Place of Presentation
      Stockholm, Sweden (Karolinska Institute)
    • Year and Date
      2015-12-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 脂質代謝を制御する微生物由来化合物2015

    • Author(s)
      供田 洋
    • Organizer
      北里大学薬学部創設50周年記念第34回白金シンポジウム
    • Place of Presentation
      北里大学薬学部コンベンションホール(東京都港区)
    • Year and Date
      2015-02-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670050
  • [Presentation] 海洋由来放線菌が生産する細胞内中性脂質制御物質に関する研究2015

    • Author(s)
      小林啓介、福田隆志、寺原 猛、春成円十朗、今田千秋、供田 洋
    • Organizer
      第17回マリンバイオテクノロジー学会大会
    • Place of Presentation
      東京(東京海洋大学)
    • Year and Date
      2015-05-31
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 脂質代謝を制御する微生物由来化合物2015

    • Author(s)
      供田 洋
    • Organizer
      北里大学薬学部創設50周年記念第34回白金シンポジウム
    • Place of Presentation
      東京(北里大学白金キャンパス)
    • Year and Date
      2015-02-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 温泉由来真菌 BF142 株の産生する新規中性脂質生成阻害物質に関する研究2015

    • Author(s)
      古川茶勲、福田隆志、小林啓介、内田龍児、供田 洋
    • Organizer
      新規素材探索研究会 第14回セミナー
    • Place of Presentation
      神奈川(新横浜フジビューホテル)
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 微生物由来脂質代謝阻害剤を求めて---発見、ケミカルバイオロジー、創薬へ --2014

    • Author(s)
      供田 洋
    • Organizer
      第6回ケミカルバイオロジー勉強会
    • Place of Presentation
      鈴木梅太郎ホール(埼玉県・和光市)
    • Year and Date
      2014-04-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670050
  • [Presentation] Discovery of useful bioactive compounds from microorganisms.2014

    • Author(s)
      Tomoda H
    • Organizer
      Okinawa Institute of Science and Technology Graduate University (OIST)
    • Place of Presentation
      沖縄(OIST)
    • Year and Date
      2014-12-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] 微生物由来脂質代謝阻害剤を求めて---発見、ケミカルバイオロジー、創薬へ ---2014

    • Author(s)
      供田 洋
    • Organizer
      第6回ケミカルバイオロジー研究会
    • Place of Presentation
      埼玉(和光)
    • Year and Date
      2014-04-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26253009
  • [Presentation] Mechanism of action of new anti-infectious agents from microorganisms2011

    • Author(s)
      Tomoda H.
    • Organizer
      The Uehara Memorial Foundation Symposium
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-06-08
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] Mechanism of action of new anti-infectious agents from microorganisms2011

    • Author(s)
      Tomoda H
    • Organizer
      The uehara memorial foundation symposium 2011
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-06-08
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] 微生物由来の抗MRSA剤の作用機構の解析2011

    • Author(s)
      供田洋
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(一般シンポジウム)
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] 微生物由来の抗MRSA剤の作用機構の解析2011

    • Author(s)
      供田洋
    • Organizer
      日本薬学会第131年会一般シンポジウム
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] Mechanism of action of cyslabdan, a potentiator of imipenem activity against MRSA2011

    • Author(s)
      Tomoda H
    • Organizer
      Inaugural Metting of Bergey's International Society for Microbial Systematics
    • Place of Presentation
      Beijing, China
    • Year and Date
      2011-05-22
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] New anti-mycobacterial peptide antibiotics, lariatin and calpinactam2010

    • Author(s)
      Tomoda H
    • Organizer
      FIP2010
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] 真菌由来beauveroilide III のACAT1 選択的阻害活性に関する研究2009

    • Author(s)
      大場未央、松田大介、大城太一、土井隆行、高橋孝志、大村智、供田洋
    • Organizer
      日本薬学会第129年回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] Discovery for New Anti-Mycobacterial Agents from Microorganisms.2009

    • Author(s)
      Tomoda H
    • Organizer
      Australia-Japan Workshop on Biodiversity
    • Place of Presentation
      Canberra, Australia
    • Year and Date
      2009-10-28
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] カイコ感染症モデルを利用した治療効果を示す抗生物質の探索2009

    • Author(s)
      供田洋
    • Organizer
      医学・創薬研究を支えるヒトと昆虫の生物資源-病理と病態モデル-
    • Place of Presentation
      東京
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-21310146
  • [Presentation] ACAT2 選択的阻害剤ピリピロペンA の抗動脈硬化作用2009

    • Author(s)
      坂井謙斗、大城太一、松田大介、野牛宏晃、Lawrence Rudel、大村智、石橋俊、供田洋
    • Organizer
      日本薬学会第129年回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] ACAT2 選択的阻害剤pyripyropene Aの誘導体合成と構造活性相関2009

    • Author(s)
      大多和正樹、山崎寛之、松田大介、大城太一、針谷義弘、長光亨、大村智、供田洋
    • Organizer
      日本薬学会第129年回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] アイソザイム選択的阻害剤の開拓2009

    • Author(s)
      供田洋
    • Organizer
      日本薬学会第129年回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] ACAT 阻害剤の復活をめざして2008

    • Author(s)
      供田洋
    • Organizer
      北里大学薬学部特別公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-10-08
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] 天然資源からの新しい抗動脈硬化薬の開拓研究2008

    • Author(s)
      供田洋
    • Organizer
      動脈硬化Update2008
    • Place of Presentation
      東京
    • Year and Date
      2008-09-06
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] 真菌FO-2942 株の生産する新しいamidepsine 成分に関する研究2008

    • Author(s)
      高木陽一, 猪腰淳嗣, 内田龍児, 増間碌郎, 大村智, 供田洋
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] Suppression of lipid droplet accumulation in mouse peritoneal macrophages by piperine2008

    • Author(s)
      D. Matsuda, S. Ohte, T. Ohshiro, W. Jiang, L. L. Rudel, B. Hong, S. Si, H. Tomoda
    • Organizer
      The 4^<th> Korea-Japan Joint Symposium Chemical Biology for Bioactive Molecules
    • Place of Presentation
      Kinugawa, Tochigi, Japan
    • Year and Date
      2008-05-21
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] マクロファージ内脂肪滴蓄積阻害剤beauveriolide の標的分子の解析2008

    • Author(s)
      松田大介、大城太一、土井隆行、大場未央、高橋孝志、大村智、供田洋
    • Organizer
      第31回日本分子生物学会年会第81 回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] Microbial products inhibiting neutral lipid synthesis2008

    • Author(s)
      Tomoda H.
    • Organizer
      The 12th Japan-Korea Joint Symposium Drug Design and Development
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] ACAT阻害剤beauveriolide III の誘導体合成と構造活性相関2008

    • Author(s)
      伊牟田聡、広木康洋、土黒一郎、高橋孝志、土井隆行、大城太一、山崎寛之、松田大介、大村智、供田洋
    • Organizer
      第27回メディシナルケミストリーシンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-26
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] ACAT2 選択的阻害剤pyripyropene Aの誘導体合成と構造活性相関2008

    • Author(s)
      大多和正樹、山崎寛之、松田大介、大城太一、針谷義宏、長光亨、大村智、供田洋
    • Organizer
      第27回メディシナルケミストリーシンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-26
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] 海洋由来真菌 Aspergillus clavatonanicusFKI-1746 株の生産する新規マクロファーシ脂肪滴蓄積阻害物質2008

    • Author(s)
      小山信裕、井上勇佑、野中健一、山口裕一、増間碌郎、大村 智、供田 洋
    • Organizer
      第11 回マリンバイオテクノロジー学会大会
    • Place of Presentation
      京都
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] 黒胡椒成分piperine によるマクロファージ内脂肪滴蓄積阻害作用2008

    • Author(s)
      松田大介、大城太一、司書毅、供田洋
    • Organizer
      第128 回日本薬学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] マクロファージ内脂肪滴蓄積阻害活性を示すツルリンドウ由来成分の作用機序の解析2008

    • Author(s)
      松田大介、小林翔、深澤征義、西島正弘、花田賢太郎、司書毅、供田洋
    • Organizer
      第21 回バイオサイエンスフォーラム
    • Place of Presentation
      相模原
    • Year and Date
      2008-08-01
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] Bioactive products from marine-derived microorganism as probes in chemical biology2007

    • Author(s)
      H. Tomoda, D. Matsuda
    • Organizer
      VI^<TM> US-Japan seminar : frontiers in marine natural productsresearch
    • Place of Presentation
      Park city, Utah, USA
    • Year and Date
      2007-06-06
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] Bioactive products from marine-derived microorganism as probes in chemical biology2007

    • Author(s)
      Tomoda, H.&Matsuda, D.
    • Organizer
      VI^<TM> US-Japan seminar:frontiers in marine natural products research
    • Place of Presentation
      Park city,Utah,USA
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] 海洋由来脂質代謝阻害剤を用いたケミカルバイオロジー2007

    • Author(s)
      松田 大介、 供田 洋
    • Organizer
      第10回マリンバイオテクノロジー学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Presentation] Bioactive products from marine-derived microorgamsm as probes in chemical biology2007

    • Author(s)
      Tomoda, H. & Matsuda, D.
    • Organizer
      VI^<TM> us-Japan seminar: frontiers in marine naturalproducts research
    • Place of Presentation
      Park city, Utah
    • Data Source
      KAKENHI-PROJECT-16073215
  • [Presentation] 海洋由来脂質代謝阻害剤を用いたケミカルバイオロジー2007

    • Author(s)
      松田 大介、供田 洋
    • Organizer
      第10回マリンバイオテクノロジー学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18390008
  • [Presentation] 海洋由来脂質代謝阻害剤を用いたケミカルバイオロジー2007

    • Author(s)
      松田大介、供田洋
    • Organizer
      第10回マリンバイオテクノロジー学会
    • Place of Presentation
      山形
    • Year and Date
      2007-05-27
    • Data Source
      KAKENHI-PROJECT-18390008
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  • 2.  INOKOSHI Junji (30151640)
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