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OHMORI Shigeru  大森 栄

ORCIDConnect your ORCID iD *help
Researcher Number 70169069
Other IDs
Affiliation (based on the past Project Information) *help 2014 – 2018: 信州大学, 学術研究院医学系(医学部附属病院), 教授
2003 – 2016: 信州大学, 医学部附属病院, 教授
2011: 信州大学, 医学部付属病院, 教授
2010: 信州大学, 医学部・附属病院, 教授
2004: 信州大学, 医学部, 教授 … More
1998: 千葉大学, 医学部附属病院, 助教授
1993 – 1998: 千葉大学, 医学部・附属病院, 助教授
1997: 千葉大学, 医学部・付属病院, 助教授
1994: 千葉大学, 医学部付属病院薬剤部, 助教授
1994: 千葉大学, 医学部附属病院, 助教授
1993 – 1994: 千葉大学, 医学部・付属病院薬剤部, 助教授
1991 – 1992: 千葉大学, 薬学部, 助手
1986: Fac. of Pharmaceut. Sci., Chiba Univ., Research Assistant, 薬学部, 教務職員 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / 応用薬理学・医療系薬学 / Biological pharmacy
Except Principal Investigator
Medical pharmacy / 応用薬理学・医療系薬学 / 医薬分子機能学 / Environmental and hygienic pharmacy
Keywords
Principal Investigator
肝細胞 / サル / CYP3A / 薬物代謝酵素 / シトクロムP450 / 分化 / 薬物動態 / HNF-3β / 胚性幹細胞 / 薬物代謝 … More / チトクロムP450 / 相互作用 / 漢方薬 / P450 / 肝 / グルココルチコイド受容体 / エピジェネティクス / 発現調節因子 / 発現制御 / CYP3A7 / SULT1E1 / 糖質コルチコイド / ヒト胎児肝細胞 / cyochrome P450 / hepatoblast / differentiate / hepatocyte / embryonic stem cell / monkey / mouse / Cyp7bl / Cyp7al / Cyp3all / Cyplal / 薬物トランスポーター / 胚様体 / CYP3A66 / CYP3A8 / 肝芽細胞 / マウス / Microsomes / Drug metabolism / Cytochrome P450 / Liver / Brain / Monkey / チトクロームP450 / ミクロゾーム / シクロゾーム / 脳 / ヒトES細胞 / 胆管上皮細胞 / 分化誘導 / 低分子化合物 / 腸管上皮細胞 / iPS細胞 / ヒト人工多能性幹細胞 / 代謝学 / GATA-4 / マトリゲル / ノトプテロール / ラット / ビリルビン尿症 … More
Except Principal Investigator
CYP3A7 / 薬物代謝酵素 / 薬物代謝 / CYP3A4 / ヒト胎児肝細胞 / drug metabolism / CYP / 胎児毒性 / リファンピシン / 薬物動態 / P-450 / グルココルチコイド受容体 / デキサメタゾン / steroid metabolism / ステロイド代謝 / グルタチオンS-トランスフェラーゼ / 分化 / ラット / ヒトiPS細胞 / 胎児 / CYP3A / シトクロムP450 / 肝細胞 / GST / Isozyme / Experimantal animals / Drug metabolism / Teratogenicity / Developmental toxicity / Chemicals / Whole embryo culture / invitro毒科学 / 胎仔培養 / 代替法 / 8-GTP / アイソザイム / 性差 / 種差 / サル / ハムスター / モルモット / マウス / 催奇形性 / 発生毒性 / 化学物質 / 培養 / 卵膜 / 薬物療法 / 妊娠 / エピジェネティクス / PGC1α / HNF4α / プレグネノロンX受容体 / RU486 / rifampicin / glucocorticoid receptor / dexamethasone / cytochrome P450 / human fetal liver cell / RU-486 / 移植 / サイトケラチン7 / メチル化 / グルココルチコイド受容 / オンコスタチンM / 正常ヒト胎児肝細胞 / RNA干渉法 / fetal toxicity / expression in COS-7 cells and TN-5 cells / CYP enzymes / ヒト胎児肝P450 / スラロイド代謝 / CYP3A酵素 / esterase / CO57 cells / CYP 450 / glutathion S-transferase / carboxyl esterase / グルタチオン S-トランスフェラーゼ / P450 / 培養細胞 / 発現 / 遺伝子導入 / カルボキシルエステラーゼ / エステラーゼ / スクラーゼ・イソマルターゼ / 低分子化合物 / トランスポーター / 人工多能性幹細胞 / 薬物動態学 / iPS細胞 / 薬学 / デバイス / 経口バイオアベイラビリティ / 薬物トランスポーター / 初回通過効果 / 腸管上皮細胞 / 分化誘導 / マクロファージ / モノクローナル抗体製剤 / 薬物相互作用 / 分子標的薬 / リツキシマブ / 抗体医薬 / インフュージョンリアクション / monoclonal antibody / infusion reaction / Rituximab / 発現解析 / FAH / ES細胞 / TK-NOGマウス / tk-NOGマウス / マーモセット / カニクイザル / ラットiPS細胞 / 異種動物間キメラ / サルiPS細胞 / 胚盤胞補完法 / 発がん予防機構 / ビタミンKサイクル / VKORC1 / PIVKA-II / iPS 細胞 / ビタミン K / ケモプリベンション / デスフェロキサミン / 胚性幹細胞 / 薬物動態予測モデル / 妊婦 / peroxisome proliferator activated receptor γ coactivator 1α / hepatocyte nuclear factor 4α / 転写因子 / pregnane X receptor / 低酸素誘導因子 / 低酸素 / コリプレッサー / コアクチベーター / 転写活性 / ヒト胎児 / 代謝学 / GST-π / GST-α / 腎障害 / Pー450IA / チトクロ-ムPー450 / 胎児肝 Less
  • Research Projects

    (22 results)
  • Research Products

    (97 results)
  • Co-Researchers

    (20 People)
  •  Elucidation of mechanisms underlying different glucocorticoid responses of drug-metabolizing enzymes, SULT1E1 and CYP3A7, in human fetal liver cellsPrincipal Investigator

    • Principal Investigator
      OHMORI Shigeru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  Differentiation of human iPS cells into hepatocytes and enterocytes: Development of first pass effect assessment model

    • Principal Investigator
      Matsunaga Tamihide
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagoya City University
  •  Estimation of fetotoxicity of chemical compounds with human fetal liver cells and molecular basis of their toxicities

    • Principal Investigator
      YAMAORI Satoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      Shinshu University
  •  Investigation of the infusion reaction development coursed by molecular target medicine prescription

    • Principal Investigator
      NAKAMURA Katsunori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      University of the Ryukyus
      Nagoya City University
  •  Generation of Monkey/Mouse Chimera with Monkey Liver by Interspecific Blastocyst Injection of Monkey induced Pluripotent Stem Cells

    • Principal Investigator
      MATSUNAGA Tamihide
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagoya City University
  •  Differentiation ofhuman iPS cells into hepatocytes and bile duct epithelial cells and application to drug development studyPrincipal Investigator

    • Principal Investigator
      OHMORI Shigeru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  Chemopreventive effects of vitamin K cycle using human iPS cells

    • Principal Investigator
      NAKAMURA Katsunori
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Nagoya City University
      Shinshu University
  •  ヒト胎児肝細胞におけるCYP3A分子種の発現変動要因の解明

    • Principal Investigator
      MATSUNAGA Tamihide
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  妊娠と薬:胎児における薬物動態変動因子の解明

    • Principal Investigator
      松永 民秀
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  サル胚性幹細胞の肝細胞への分化と胎児薬物動態予測モデルの構築Principal Investigator

    • Principal Investigator
      大森 栄
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  Basic Study for Regenerative Medicine : Differentiate of Human Fetal Liver Cells and Application for Drug Pharmacokinetic Experiments

    • Principal Investigator
      MATSUNAGA Tamihide
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  Basic Study for Regenerative Medicine : Differentiate of Embryonic Stem Cells to Hepatocytes and Expressions of Cytochrome P450 in the Differentiating CellsPrincipal Investigator

    • Principal Investigator
      OHMORI Shigeru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Shinshu University
  •  医薬品適正使用を指向した診断マーカーとしての薬物代謝酵素の有用性に関する研究

    • Principal Investigator
      北田 光一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  Studies on the prediction of fetal toxicity caused by drugs

    • Principal Investigator
      KITADA Mitsukazu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  薬物間相互作用の予測に関する研究:漢方薬との相互作用を中心としてPrincipal Investigator

    • Principal Investigator
      大森 栄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  最適な薬物投与設計を目指した薬物相互作用の予測に関する研究Principal Investigator

    • Principal Investigator
      大森 栄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  Studies on prediction of fetal toxicity caused by drugs.

    • Principal Investigator
      KITADA Mitsukazu
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  Studies on the metabolism and toxicity of drugs using mammalian cells expressed in drug metabolism enzymes

    • Principal Investigator
      SATOH Tetsuo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Chiba University
  •  Studies on the structure and function of cytochrome P450 in monkey brainPrincipal Investigator

    • Principal Investigator
      OHMORI Shigeru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  高ビリルビン尿症ラットの肝シトクロムP-450分子種変動機構の解明Principal Investigator

    • Principal Investigator
      大森 栄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  胎児性肝チトクロ-ムPー450に関する薬理学的・毒性学的研究

    • Principal Investigator
      金久保 好男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University
  •  Resolving studies on mechanism of developmental toxicity induced by chemical substances in culture system

    • Principal Investigator
      KITAGAWA Haruo
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Chiba University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2005

All Journal Article Presentation Book

  • [Book] 薬物代謝学医療薬学・医薬品開発の基礎として第3版2.薬物の代謝反応2010

    • Author(s)
      大森栄(分担執筆)
    • Total Pages
      26
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Book] 薬物代謝学医療薬学・医薬品開発の基礎として第3版2010

    • Author(s)
      大森栄(分担執筆)
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] A Specific Probe Substrate for Evaluation of CYP4A11 Activity in Human Tissue Microsomes and a Highly Selective CYP4A11 Inhibitor: Luciferin-4A and Epalrestat2018

    • Author(s)
      Yamaori Satoshi、Araki Noriyuki、Shionoiri Mio、Ikehata Kurumi、Kamijo Shinobu、Ohmori Shigeru、Watanabe Kazuhito
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: 366 Issue: 3 Pages: 446-457

    • DOI

      10.1124/jpet.118.249557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08354, KAKENHI-PROJECT-16K08368
  • [Journal Article] 切迫早産治療薬としてニフェジピンが奏功した一例2016

    • Author(s)
      小澤秀介, 小林愛子, 高津亜希子, 神田博仁, 山折 大, 塩沢丹里, 大森 栄
    • Journal Title

      医療薬学

      Volume: 42 Pages: 202-208

    • NAID

      130005440106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460167
  • [Journal Article] Possible Mechanism of Iguratimod–Warfarin Interaction2015

    • Author(s)
      Yamaori S, Takami K, Shiozawa A, Sakuyama K, Matsuzawa N, Ohmori S
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 38 Issue: 3 Pages: 441-447

    • DOI

      10.1248/bpb.b14-00711

    • NAID

      130004872267

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460167
  • [Journal Article] Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells.2014

    • Author(s)
      Kondo Y, Iwao T, Yoshihashi S, Mimori K, Ogihara R, Nagata K, Kurose K, Saito M, Niwa T, Suzuki T, Miyata N, Ohmori S, Nakamura K, Matsunaga T.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 8 Pages: 1-11

    • DOI

      10.1371/journal.pone.0104010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460193, KAKENHI-PROJECT-25460195, KAKENHI-PROJECT-26293036
  • [Journal Article] An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity2014

    • Author(s)
      Kondo Y, Iwao T, Nakamura K, Sasaki T, Takahashi S, Kamada N, Matsubara T, Gonzalez FJ, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Toyoda M, Umezawa A, Nagata K, Matsunaga T, Ohmori S
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 29 Issue: 3 Pages: 237-243

    • DOI

      10.2133/dmpk.DMPK-13-RG-104

    • NAID

      130004463382

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390036, KAKENHI-PROJECT-25460195, KAKENHI-PROJECT-25860120
  • [Journal Article] An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity.2014

    • Author(s)
      Kondo Y, Iwao T, Nakamura K, Sasaki T, Takahashi S, Kamada N, Matsubara T, Gonzalez FJ, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Toyoda M, Umezawa A, Nagata K, Matsunaga T, Ohmori S
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 29 Pages: 237-243

    • NAID

      130004463382

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293036
  • [Journal Article] An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells Retaining Drug Metabolizing Activity.2014

    • Author(s)
      Kondo Y, Iwao T, Nakamura K, Sasaki T, Takahashi S, Kamada N, Matsubara T, Gonzalez FJ, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Toyoda M, Umezawa A, Nagata K, Matsunaga T, Ohmori S.
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 29 Pages: 237-243

    • NAID

      130004463382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460193
  • [Journal Article] Differentiation of monkey embryonic stem cells to hepatocytes by feeder-free dispersion culture and expression analyses of cytochrome P450 enzymes responsible for drug metabolism2013

    • Author(s)
      Maruyama J, Matsunaga T, Yamaori S, Sakamoto S, Kamada N, Nakamura K, Kikuchi S, Ohmori S
    • Journal Title

      Biol Pharm Bull

      Volume: 36 Pages: 292-298

    • NAID

      130002480763

    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Differentiation of Monkey Embryonic Stem Cells to Hepatocytes by Feeder-Free Dispersion Culture and Expression Analyses of Cytochrome P450 Enzymes Responsible for Drug Metabolism2013

    • Author(s)
      Maruyama J, Matsunaga T, Yamaori S, Sakamoto S, Kamada N, Nakamura K, Kikuchi S, Ohmori S
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 36 Issue: 2 Pages: 292-298

    • DOI

      10.1248/bpb.b12-00866

    • NAID

      130002480763

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Differentiation of monkey embryonic stem cells to hepatocytes by feeder-free dispersion culture and expression analyses of cytochrome p450 enzymes responsible for drug metabolism.2013

    • Author(s)
      Maruyama J, Matsunaga T, Yamaori S, Sakamoto S, Kamada N, Nakamura K, Kikuchi S, Ohmori S.
    • Journal Title

      Biol Pharm Bull

      Volume: 36(2) Pages: 292-298

    • NAID

      130002480763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] Hepatocyte Nuclear Factor 6 Activates the Transcription of <i>CYP3A4</i> in Hepatocyte-like Cells Differentiated from Human Induced Pluripotent Stem Cells2013

    • Author(s)
      Sasaki T, Takahashi S, Numata Y, Narita M, Tanaka Y, Kondo Y, Matsunaga T, Ohmori S, Nagata K
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 28 Issue: 3 Pages: 250-259

    • DOI

      10.2133/dmpk.DMPK-12-RG-132

    • NAID

      130004463310

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028, KAKENHI-PROJECT-23790193
  • [Journal Article] Clinical Evidence of Pharmacokinetic Changes in Thalidomide Therapy2013

    • Author(s)
      Nakamura K, Matsuzawa N, Ohmori S, Ando Y, Yamazaki H, Matsunaga T
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 28 Issue: 1 Pages: 38-43

    • DOI

      10.2133/dmpk.DMPK-12-RV-089

    • NAID

      130004463295

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028, KAKENHI-PROJECT-23590200
  • [Journal Article] An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells Retaining Drug Metabolizing Activity.2013

    • Author(s)
      Kondo Y, Iwao T, Nakamura K, Sasaki T, Takahashi S, Kamada N, Matsubara T, Gonzalez FJ, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Toyoda M, Umezawa A, Nagata K, Matsunaga T, Ohmori S.
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 0 Pages: 0-0

    • NAID

      130004463382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460193
  • [Journal Article] Clinical evidence of the pharmacokinetics change in thalidomide therapy2013

    • Author(s)
      Nakamura K, Matsuzawa N, Ohmori S, Ando Y, Yamazaki H, Matsunaga T
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 28 Pages: 38-43

    • NAID

      130004463295

    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Hepatocyte nuclear factor 6 activates the transcription of CYP3A4 in hepatocyte-like cells differentiated from human induced pluripotent stem cells2013

    • Author(s)
      Sasaki T, Takahashi S, Numata Y, Narita M, Tanaka Y, Kondo Y, Matsunaga T, Ohmori S, Nagata K
    • Journal Title

      Drug Metabol Pharmacokinet

      Volume: 28 Pages: 250-259

    • NAID

      130004463310

    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Effect of CYP2C19 gene variations on thalidomide treated patients in Japanese.2012

    • Author(s)
      Matsuzawa N, Nakamura K, Matsuda M, Ishida F, Ohmori S
    • Journal Title

      Biol Pharm Bull

      Volume: 35(3) Pages: 317-320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] Treatment of a GIST patient with modifieddose of sunitinib by measurement of plasma drug concentrations.2012

    • Author(s)
      Hashita T, Katsuyama Y, Nakamura K, Momose Y, Komatsu D, Koide N, Miyagawa S, Nakamura T, Yamamoto K, Ohmori S.
    • Journal Title

      Oncol Lett.

      Volume: 4(3) Pages: 501-504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] Influence of Cytochrome P450 2C19 Gene Variations on Pharmacokinetic Parameters of Thalidomide in Japanese Patients2012

    • Author(s)
      Matsuzawa N, Nakamura K, Matsuda M, Ishida F, Ohmori S
    • Journal Title

      Biol Pharm Bull

      Volume: 35 Pages: 317-320

    • NAID

      130001872311

    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Effects of hypoxia-inducible factor-1α chemical stablizer, CoCl_2 and hypoxia on gene expression of CYP3As in human fetal liver cells2012

    • Author(s)
      Suzuki E, Matsunaga T, Aonuma A, Sasaki T, Nagata K, Ohmori S
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Evaluation of human embryonic stem cell-derived hepatocyte-like cells for detection of CYP1A inducers2012

    • Author(s)
      Tsuchiya H, Matsunaga T, Aikawa K, Kamada N, Nakamura K, Ichikawa H, Sasaki K, Ohmori S
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 27 Pages: 598-604

    • NAID

      130004933512

    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Mechanisms of CYP3A induction by glucocorticoids in human fetal liver cells2012

    • Author(s)
      Matsunaga T, Maruyama M, Matsubara T, Nagata K, Yamazoe Y, Ohmori S
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 27 Pages: 653-657

    • NAID

      130004933510

    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects.2012

    • Author(s)
      Nakamura K, Obayashi K, Araki T, Aomori T, Fujita Y, Okada Y, Kurabayashi M, Hasegawa A, Ohmori S, Nakamura T, Yamamoto K.
    • Journal Title

      J Clin Pharm Ther

      Volume: 37(4) Pages: 481-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.2012

    • Author(s)
      Takezawa T, Matsunaga T, Aikawa K, Nakamura K, Ohmori S.
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 27(4) Pages: 430-438

    • NAID

      130004463268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR overexpressed in human fetal liver cells.2012

    • Author(s)
      Takezawa T, Matsunaga T, Aikawa K, Nakamura K, Ohmori S
    • Journal Title

      Drug Metabol Pharmacokinet

      Volume: 27 Pages: 430-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Effects of hypoxia-inducible factor-1α chemical stabilizer, CoCl_2 and hypoxia on gene expression of CYP3As in human fetal liver cells.2012

    • Author(s)
      Suzuki E, Matsunaga T, Aonuma A, Sasaki T, Nagata K, Ohmori S
    • Journal Title

      Drug Metabol Pharmacokinet

      Volume: 27 Pages: 398-404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Evaluation of human embryonic stem cell-derived hepatocyte-like cells for detection of CYP1A inducers. Drug Metab Pharmacokinet.2012

    • Author(s)
      Tsuchiya H, Matsunaga T, Aikawa K, Kamada N, Nakamura K, Ichikawa H, Sasaki K, Ohmori S.
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 27(6) Pages: 598-604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] Influence of Cytochrome P450 2C19 Gene Variations on Pharmacokinetic Parameters of Thalidomide in Japanese Patients2012

    • Author(s)
      Matsuzawa N, Nakamura K, Matsuda M, Ishida F, Ohmori S
    • Journal Title

      Biol Pharm Bull

      Volume: 35 Pages: 317-320

    • NAID

      130001872311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Evaluation of Human Embryonic Stem Cell-derived Hepatocyte-like Cells for Detection of CYP1A Inducers2012

    • Author(s)
      Tsuchiya H, Matsunaga T, Aikawa K, Kamada N, Nakamura K, Ichikawa H, Sasaki K, Ohmori S
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 27 Issue: 6 Pages: 598-604

    • DOI

      10.2133/dmpk.DMPK-12-RG-017

    • NAID

      130004933512

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR overexpressed in human fetal liver cells2012

    • Author(s)
      Takezawa T, Matsunaga T, Aikawa K, Nakamura K, Ohmori S
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Journal Article] Mechanisms of CYP3A Induction by Glucocorticoids in Human Fetal Liver Cells2012

    • Author(s)
      Matsunaga T, Maruyama M, Matsubara T, Nagata K, Yamazoe Y, Ohmori S
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 27 Issue: 6 Pages: 653-657

    • DOI

      10.2133/dmpk.DMPK-12-NT-018

    • NAID

      130004933510

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] ES細胞の肝細胞への分化と薬物動態試験への応用.2010

    • Author(s)
      松永民秀,大森栄
    • Journal Title

      医学のあゆみ

      Volume: 232(2) Pages: 447-457

    • Data Source
      KAKENHI-PROJECT-22590133
  • [Journal Article] ES細胞の肝細胞への分化と薬物動態試験への応用2010

    • Author(s)
      松永民秀, 大森栄
    • Journal Title

      医学のあゆみ 232

      Pages: 99-104

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] CYP3As gene expression and testosterone 6β-hydroxylase activity in human fetal membranes and placenta at full term.2010

    • Author(s)
      Maezawa K, Matsunaga T, Takezawa T, Kanai M, Ohira S, Ohmori S
    • Journal Title

      Biol Pharm Bull 33

      Pages: 249-254

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] ES細胞の肝細胞への分化と薬物動態試験への応用2010

    • Author(s)
      松永民秀, 大森栄
    • Journal Title

      医学のあゆみ

      Volume: 232 Pages: 99-109

    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Cytochrome P450 3As Gene Expression and Testosterone 6.BETA.-Hydroxylase Activity in Human Fetal Membranes and Placenta at Full Term2010

    • Author(s)
      Maezawa K, Matsunaga T, Takezawa T, Kanai M, Ohira S, Ohmori S
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 33 Issue: 2 Pages: 249-254

    • DOI

      10.1248/bpb.33.249

    • NAID

      130000156632

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Journal Article] Role of dexamethasone and oncostatin M on the formation of vacuoles in human fetal liver cells.2009

    • Author(s)
      Teramoto T, Matsunaga T, Toba M, Sunazuka T, Omura S, Ohmori S
    • Journal Title

      Biol Pharm Bull 32

      Pages: 209-212

    • NAID

      110007042161

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] Differentiation of monkey embryonic stem cells into hepatocytes and mRNA expression of cytochrome P450 enzymes responsible for drug metabolism : Comparison of embryoid body formation conditions and matrices.2009

    • Author(s)
      Momose Y, Matsunaga T, Murai K, Takezawa T, Ohmori S
    • Journal Title

      Biol Pharm Bull 32

      Pages: 619-626

    • NAID

      110007160692

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] Formation of large vacuoles induced by cooperative effects of oncostatin M and dexamethasone in human fetal liver cells.2008

    • Author(s)
      Matsunaga T, Toba M, Teramoto T, Mizuya M, Aikawa K, Ohmori S
    • Journal Title

      Med Mol Morphol 41

      Pages: 53-58

    • NAID

      10024380775

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] ヒト胎児肝細胞におけるCYP3A発現変動とES細胞研究2008

    • Author(s)
      松永民秀, 大森栄
    • Journal Title

      Pharma VISION NEWS No.12

      Pages: 19-23

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] 胎児におけるシトクロムP450の発現:肝臓のCYP3A分子種を中心として2008

    • Author(s)
      松永民秀、丸山昌孝、大森栄
    • Journal Title

      信州医学雑誌 56

      Pages: 7-16

    • NAID

      130004551686

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] Expression of cytochrome P450 and transcription factors during in vitro differentiation of mouse embryonic stem cells into hepatocytes.2008

    • Author(s)
      Maezawa K, Miyazato K, Matsunaga T, Momose Y, Imamura T, Johkura K, Sasaki K, Ohmori S
    • Journal Title

      Drug Metabol Pharmacokin 23

      Pages: 188-195

    • NAID

      130005024407

    • Data Source
      KAKENHI-PROJECT-20590142
  • [Journal Article] Determination of P-glycoprotein ATPase Activity using Luciferase.2006

    • Author(s)
      Matsunaga T, Kose E, Yasuda S, Ise H, Ikeda U, Ohmori S
    • Journal Title

      Biochem Pharm Bull 29巻

      Pages: 560-564

    • NAID

      110005602145

    • Data Source
      KAKENHI-PROJECT-18590138
  • [Journal Article] Determination of P-glycoprotein ATPase Activity using Luciferase.2006

    • Author(s)
      Matsunaga T, Kose E, Yasuda S, Ise H, Ikeda U, Ohmori S
    • Journal Title

      Biochem Pharm Bull 29巻

      Pages: 560-564

    • NAID

      110005602145

    • Data Source
      KAKENHI-PROJECT-17659044
  • [Journal Article] Simple and highly sensitive method for determination of P-glycoprotein ATPase activity using Luciferase.2005

    • Author(s)
      Ohmori S et al.
    • Journal Title

      Drug Metab Rev 37

      Pages: 176-176

    • Data Source
      KAKENHI-PROJECT-17659044
  • [Journal Article] Simple and highly sensitive method for determination of P-glycoprotein ATPase activity using Luciferase.2005

    • Author(s)
      Ohmori S et al.
    • Journal Title

      Drug Metab Rev 37

      Pages: 176-176

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390047
  • [Journal Article] Simple and highly sensitive method for determination of P-glycoprotein ATPase activity using Luciferase.2005

    • Author(s)
      Ohmori S et al.
    • Journal Title

      Drug Metab Rev 37

      Pages: 176-176

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590109
  • [Presentation] Characterization of antihypertensive drugs as potent inhibitors of CYP2J22018

    • Author(s)
      Yamaori S, Ikemura N, Kobayashi C, Kamijo S, Ohmori S
    • Organizer
      22nd North American International Society for the Study of Xenobiotics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08368
  • [Presentation] ヒト胎児肝細胞における糖質コルチコイドによる硫酸転移酵素SULT1E1の発現誘導2017

    • Author(s)
      山折 大、相川香織、上条しのぶ、松永民秀、大森 栄
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-16K08368
  • [Presentation] エパルレスタットによるCYP4A11の選択的阻害作用2015

    • Author(s)
      山折 大, 荒木規行, 池畑くるみ, 大森 栄, 渡辺和人
    • Organizer
      日本薬物動態学会第30回年会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2015-11-12
    • Data Source
      KAKENHI-PROJECT-25460167
  • [Presentation] Potency and mechanism of CYP2J2 inhibition by major phytocannabinoids2015

    • Author(s)
      Yamaori S, Nagata Y, Ohmori S, Yamamoto I, Watanabe K
    • Organizer
      20th North American ISSX Meeting
    • Place of Presentation
      Orlando (USA)
    • Year and Date
      2015-10-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460167
  • [Presentation] ダナゾールのヒトCYP3A活性に対する阻害作用2014

    • Author(s)
      山折 大,津田有加,大森 栄,渡辺和人
    • Organizer
      医療薬学フォーラム2014/第22回クリニカルファーマシーシンポジウム
    • Place of Presentation
      ビッグサイトTFTホール
    • Year and Date
      2014-06-29
    • Data Source
      KAKENHI-PROJECT-25460167
  • [Presentation] Evaluation of Luciferin-4A O-demethylase activity as a CYP4A11 marker in human liver and kidney microsomes2014

    • Author(s)
      Yamaori S, Shionoiri M, Ohmori S, Watanabe K
    • Organizer
      19th North American ISSX Meeting and 29th JSSX Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2014-10-20
    • Data Source
      KAKENHI-PROJECT-25460167
  • [Presentation] ヒト人工多能性幹細胞の肝細胞への分化における変法L-15 培地及び血清の効果2013

    • Author(s)
      松永民秀, 近藤祐樹, 荻原留理, 岩尾岳洋, 永田 清, 黒瀬光一, 堀川隆司, 丹羽卓朗, 山折 大, 大森 栄, 中村克徳
    • Organizer
      フォーラム2013 : 衛生薬学・環境トキシコロジー
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] Pharmacokinetic function of hepatocyte-like cells differentiated from human iPS cells2013

    • Author(s)
      Kondo Y, Iwao T, Ogihara R, Sasaki T, Nagata K, Kurose K, Horikawa T, Niwa T, Yamaori S, Ohmori S, Nakamura K Matsunaga T
    • Organizer
      日本薬物動態学会第28回年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] Guiding the differentiation of human induced pluripotent stem cells into definitive endoderm using a combination of small-molecule compounds2013

    • Author(s)
      Ogihara R, Kondo Y, Iwao T, Yamaori S, Ohmori S, Nakamura K, Matsunaga T
    • Organizer
      日本薬物動態学会第28回年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] ヒト人工多能性幹細胞から分化させた肝細胞様細胞による薬物代謝酵素の酵素誘導評価2012

    • Author(s)
      中村克徳, 近藤祐樹, 杉山留理, 相川香織, 松永民秀, 大森 栄
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] ヒト人工多能性幹細胞から分化させた肝細胞様細胞による薬物代謝酵素の酵素誘導評価2012

    • Author(s)
      中村克徳、近藤祐樹、杉山留理、相川香織、松永民秀、大森栄
    • Organizer
      日本薬学会第132年回
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト人工多能性幹細胞から分化させた肝細胞による薬物代謝酵素の酵素誘導評価2012

    • Author(s)
      中村克徳, 近藤祐樹, 杉山留理, 相川香織, 松永民秀, 大森 栄
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] Small Molecule Compounds Enhance Differentiation to Hepatocytes from induced Pluripotent Stem Cells.2012

    • Author(s)
      Yuki Kondo, Takahiro Iwao, Sachimi Yoshihashi, Kayo Mimori, Ruri Sugiyama, Takamitsu Sasaki, Kiyoshi Nagata, Kouichi Kurose, Takuro Niwa, Satoshi Yamaori, Shigeru Ohmori, Katsunori Nakamura, Tamihide Matsunaga
    • Organizer
      第27回日本薬物動態学会年会
    • Place of Presentation
      船堀
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] Small molecule compounds enhance differentiation to hepatocytes from human induced pluripotent stem cells(低分子化合物はヒト人工多能性幹細胞から肝細胞への分化を促進する).2012

    • Author(s)
      近藤祐樹,岩尾岳洋,吉橋幸美,三森佳代,杉山留理,佐々木崇光,永田 清,黒瀬光一,丹羽卓朗,山折 大,大森 栄,中村克徳,松永民秀
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] 低分子化合物はヒト人工多能性幹細胞から肝細胞への分化を促進する2012

    • Author(s)
      近藤祐樹, 岩尾岳洋, 吉橋幸美, 三森佳代, 杉山留理, 佐々木崇光, 永田 清, 黒瀬光一, 丹羽卓朗, 山折 大, 大森 栄, 中村克徳, 松永民秀
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] 妊婦に対するお薬相談 妊娠と薬情報センター拠点病院に参加して2012

    • Author(s)
      竹田晶子, 村田稔弥, 鳥羽美恵, 丸山順也, 中村克徳, 百瀬泰行, 金井誠, 大森栄.
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト人工多能性幹細胞から分化させた肝細胞様細胞による薬物代謝酵素の酵素誘導評価2012

    • Author(s)
      中村克徳、近藤祐樹、杉山留理、相川香織、松永民秀、大森栄
    • Organizer
      日本薬学会第132年回
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] ヒトiPS細胞の肝細胞様細胞への分化と薬物代謝酵素の発現2011

    • Author(s)
      松永民秀, 近藤祐樹, 岩尾岳洋, 大森栄
    • Organizer
      日本法中毒学会第30年会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] ヒト人工多能性幹細胞の肝細胞への分化と薬物代謝酵素の発現解析2011

    • Author(s)
      近藤祐樹, 鎌田昇, 坂本栄, 松永民秀, 大森栄
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] 大型類人猿の肝薬物代謝酵素の特性について2011

    • Author(s)
      星山望,中村克徳,松永民秀,大森栄
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト人工多能性幹細胞の肝細胞への分化と薬物代謝酵素の発現解析2011

    • Author(s)
      近藤祐樹,鎌田 昇,坂本 栄,松永民秀,大森 栄
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] ヒト人工多能性幹細胞からの肝細胞への効率的な分化方法の検討2011

    • Author(s)
      近藤祐樹, 岩尾岳洋, 三森佳代, 吉橋幸美, 大森 栄, 松永民秀
    • Organizer
      第57回日本薬学会東海支部総会・大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] 正常ヒト胎児肝細胞のCYP3A発現に及ぼす擬似低酸素誘導化合物デフェロキサミンの影響2011

    • Author(s)
      青沼安希子, 鈴木英二, 中村克徳, 松永民秀, 大森栄
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] 正常ヒト胎児肝細胞の CYP3A 発現に及ぼす擬似低酸素誘導化合物デフェロキサミンの影響2011

    • Author(s)
      青沼安希子,鈴木英二,中村克徳,松永民秀,大森栄
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト iPS 細胞の肝細胞様細胞への分化と薬物代謝酵素の発現2011

    • Author(s)
      松永民秀,近藤祐樹,岩尾岳洋,大森 栄
    • Organizer
      日本法中毒学会第30 年会
    • Place of Presentation
      長崎
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] 正常ヒト胎児肝細胞のCYP3A 発現に及ぼす擬似低酸素誘導化合物デフェロキサミンの影響2011

    • Author(s)
      青沼安希子,鈴木英二,中村克徳,松永民秀,大森 栄
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] 大型類人猿の肝薬物代謝酵素の特性について2011

    • Author(s)
      星山望、中村克徳、松永民秀、大森栄
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] 遺伝薬理学を用いた個別化医療の推進に関する研究.2011

    • Author(s)
      中村克徳, 大森栄
    • Organizer
      2011年度中部乳酸菌研究会
    • Place of Presentation
      新潟市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト人工多能性幹細胞からの肝細胞への効率的な分化方法の検討.2011

    • Author(s)
      近藤祐樹,岩尾岳洋,三森佳代,吉橋幸美,大森 栄,松永民秀
    • Organizer
      第57回日本薬学会東海支部総会・大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-07-09
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] ヒト iPS 細胞の肝細胞様細胞への分化と薬物代謝酵素の発現2011

    • Author(s)
      松永民秀, 近藤祐樹, 岩尾岳洋, 大森 栄
    • Organizer
      日本法中毒学会第30年会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23390036
  • [Presentation] ヒトES由来肝細胞のCYPIA誘導剤検出系としての評価2010

    • Author(s)
      土屋広行,松永民秀,中村克徳,市川比奈子,佐々木克典,大森栄
    • Organizer
      第25回日本薬物動態学会年会
    • Place of Presentation
      大宮市
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ビタミン K 代謝の個人差と血栓塞栓症発症リスク因子の解析.2010

    • Author(s)
      中村克徳, 大森栄
    • Organizer
      2010年度中部乳酸菌研究会
    • Place of Presentation
      松本市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] サルES細胞の肝細胞への分化と薬物動態研究2010

    • Author(s)
      丸山順也,坂本栄,松永民秀,中村克徳,菊池伸次,大森栄
    • Organizer
      第25回日本薬物動態学会年会
    • Place of Presentation
      大宮市
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト卵膜および胎盤におけるCYP3A遺伝子の発現とTestosterone 6β-水酸化活性2010

    • Author(s)
      前澤佳代子, 松永民秀, 竹澤崇, 金井誠, 大平哲史, 木津純子, 大森栄
    • Organizer
      医療薬学フォーラム2010/第18回クリニカルファーマシーシンポジウム
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] 腎細胞癌患者におけるスニチニブ血中濃度と副作用の相関性.2010

    • Author(s)
      坡下真大,勝山義彦,松澤直樹,井上博夫,栗崎功己,田辺智明,中村克徳,百瀬泰行,西沢 理,大森栄.
    • Organizer
      第20回日本医療薬学会年会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] CYP2C19 遺伝子多型によるサリドマイド体内動態変化に関する研究.2010

    • Author(s)
      松澤直樹,中村克徳,百瀬泰行,松永民秀,松田正之,大森 栄
    • Organizer
      第37回日本トキシコロジー学会学術年会
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] サルES細胞の肝細胞への分化と薬物動態研究2010

    • Author(s)
      丸山順也, 坂本栄, 松永民秀, 中村克徳, 菊池伸次, 大森栄
    • Organizer
      第25回日本薬物動態学会年会
    • Place of Presentation
      大宮市
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] サル胚性幹細胞の肝細胞への分化と薬物代謝に関与するシトクロムP450のmRNA発現2010

    • Author(s)
      松永民秀, 百瀬泰行, 大森栄
    • Organizer
      日本薬学会 第130年会 シンポジウム
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] 正常ヒト胎児肝細胞のCYP3A発現に対する擬似低酸素誘導化合物の効果2010

    • Author(s)
      青沼安希子, 鈴木英二, 中村克徳, 松永民秀, 大森栄
    • Organizer
      日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2010(第20回日本病院薬剤師会東海ブロック学術大会・平成22年度日本薬学東海支部例会)
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] 遺伝子多型を考慮したサリドマイド適正使用の試み. シンポジウム 20 病院薬剤師による薬物治療個別化への遺伝子情報の活用2010

    • Author(s)
      中村克徳,松澤直樹,大森 栄
    • Organizer
      第20回日本医療薬学会年会,シンポジスト
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒト ES 由来肝細胞の CYP1A 誘導剤検出系としての評価(EVALUATION OF HUMAN EMBRYONIC STEM CELLS- DERIVEDHEPATOCYTES TO DETECTION SYSTEM OF CYPIA INDUCER).2010

    • Author(s)
      土屋広行, 松永民秀, 中村克徳, 市川比奈子, 佐々木克典, 大森栄
    • Organizer
      第25回日本薬物動態学会年会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] ヒトES由来肝細胞のCYP1A誘導剤検出系としての評価2010

    • Author(s)
      土屋広行, 松永民秀, 中村克徳, 市川比奈子, 佐々木克典, 大森栄
    • Organizer
      第25回日本薬物動態学会年会
    • Place of Presentation
      大宮市
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-22390028
  • [Presentation] HPLC-UV 検出器を用いた Sunitinib および活性代謝物N-desethylsunitinib 血中濃度測定法の確立と臨床応用.2010

    • Author(s)
      勝山善彦,坡下真大,松澤直樹,中村克徳,西澤 理,大森 栄.
    • Organizer
      第27回日本 TDM 学会学術大会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] 正常ヒト胎児肝細胞の CYP3A 発現に対する擬似低酸素誘導化合物の効果.2010

    • Author(s)
      青沼安希子,鈴木英二,中村克徳,松永民秀,大森栄.
    • Organizer
      第20回日本病院薬剤師会東海ブロック学術大会・平成22年度 日本薬学東海支部例会
    • Place of Presentation
      静岡市
    • Year and Date
      2010-11-28
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] サル ES 細胞の肝細胞への分化と薬物動態研究 (DIFFERENTIATION OF MONKEY EMBRYONIC STEM CELLS TO HEPATOCYTES AND PHARMACOKINETIC STUDIES).2010

    • Author(s)
      丸山順也, 坂本栄, 松永民秀, 中村克徳, 菊池伸次, 大森栄
    • Organizer
      第25回日本薬物動態学会年会
    • Place of Presentation
      大宮市
    • Data Source
      KAKENHI-PROJECT-22590133
  • [Presentation] Expression of cytochrome P450 and transcription factors during differentiation of mouse ES cells into hepatocytes2009

    • Author(s)
      Matsunaga T, Maezawa K, Miyazato K, Momose Y, Imamura T, Johkura K, Sasaki K, Ohmori S
    • Organizer
      16th International Conference on Cytochrome P450
    • Place of Presentation
      Nago, Okinawa, Japan
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] リファンピシンによるヒト胎児肝細胞CTP3As誘導に関する制御機構の解明2008

    • Author(s)
      松永民秀, 大森栄
    • Organizer
      平成20年度中部乳酸菌研究会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] ヒト胚性幹細胞の肝細胞への分化と動態研究2008

    • Author(s)
      松永民秀, 大森栄
    • Organizer
      第23回日本薬物動態学会年会 シンポジウム
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-20590142
  • [Presentation] 霊長類肝におけるCYP3A分子種の発現2008

    • Author(s)
      土屋広行, 丸山順也, 松永民秀, 大森栄
    • Organizer
      新手法を用いた薬物代謝酵素活性の個人差研究会
    • Place of Presentation
      福島県安達郡大玉村
    • Data Source
      KAKENHI-PROJECT-20590142
  • 1.  MATSUNAGA Tamihide (40209581)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 65 results
  • 2.  KITADA Mitsukazu (90110345)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  ISHII Itsuko (00202929)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  NAKAMURA Katsunori (20361363)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 33 results
  • 5.  YAMAORI Satoshi (40360218)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 6.  仲佐 啓詳 (60260478)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NARIMATSU Shizuo (20113037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KIMURA Kazunori (00423848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ANDO Yuichi (10360083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SATOH Tetsuo (60092061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HOSOKAWA Masakiyo (70181500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SASAKI Katsunori (30170666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KITAGAWA Haruo (60009157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  IGARASHI Takashi (60104692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  UENO Koichi (60125903)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  金久保 好男 (30004873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  力久 忠昭 (70012622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  永田 清 (80189133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  吉成 浩一 (60343399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  渡辺 和人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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