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KIKUCHI Toshihiko  菊地 俊彦

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KIKUCHI Tishihiko  菊地 俊彦

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Researcher Number 70177799
External Links
Affiliation (based on the past Project Information) *help 2006: 東北大学, 医学系研究科, 助教授
2003 – 2005: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2002: Tohoku University Hospital, Assistant Professor, 医学部附属病院, 講師
1999 – 2001: Department of Otolaryngology, Nagasaki University Hospital, Assistant Professor, 医学部・附属病院, 講師
1998: 東北大学, 医学部, 助手 … More
1990: Tohoku Univ. School of Med., Associate, 医学部, 助手
1990: 東北大学, 医学部附属病院, 助手
1989: 東北大学, 医学部・附属病院, 助手
1988: 東北大学, 医学部附属病院, 助手
1987: 東北大学, 医学部・付属病院・耳鼻咽喉科, 助手 Less
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Otorhinolaryngology
Except Principal Investigator
Otorhinolaryngology / Otorhinolaryngology
Keywords
Principal Investigator
gap junction / voltage-gated potassium channel / inner ear / connexin 26 / Kir4.1 / connexin / 内リンパ電位 / endocochlear potential / cochlea / glutamine synthetase … More / GLAST / Kv3.4 / aquaporin / Kv3.1b / nonsyndromic deafness / Brain-4 / endolymphatic potential / Na-K-Cl cotransporter / Na,K-ATPase / connexin 31 / 遺伝性難聴 / 内耳 / 免疫組織化学 / potassium channel / potassium ion recycle / deafness / 内耳内カリウムイオン循環 / kir / 前庭移行細胞 / 前庭 / Kチャネル / カリウム循環 / 内リンパ直流電位 / 難聴 / 蝸牛 / endocochlear / herediatary deafness / spiral ganglion cell / potassium ion / Navl.6 / sodium channel / pottassium ion / hereditary deafness / gas junction / non-syndromic deafness / kv3.4 / voltage-gated protassium channel / connexin26 / 老人性難聴 / J mouse / CBA / 6J mouse / C57BL / 2J mouse / DBA / inbred strains / aging … More
Except Principal Investigator
遺伝性難聴 / Brain-4 / 耳管 / 耳管開放症 / 内耳 / medical managements / VT insertion / risk factors for SOM / middle ear effusion / Secretory otitis media / サーファクタント / コラーゲン線維 / 鼓膜病理 / ケミカルメディエーター / サ-ファクテン局所療法 / 柴苓湯 / 中耳粘膜病理 / 難治例鼓膜病理 / 補体 / ケミカルミディエ-タ- / 難治化因子 / 病期分類 / 滲出性中耳炎 / 成因解析 / 治療法 / 〓出性中耳炎 / Efferent nerve terminal / Afferent nerve terminal / Inner hair cell / Outer hair cell / Cochlea / Guinea pig / High-voltage electron microscope / 遠心性神経終末 / 求心性神経終末 / 内有毛細胞 / 外有毛細胞 / 蝸牛 / モルモット / 超高圧電子顕微鏡 / hair cell / heat stress / acoustic trauma / 有毛細胞 / 熱ストレス / 音響外傷 / positional candidate gene approach / linkage analysis / WFS1 gene / low frequency sensorineural hearing loss / hereditary hearing loss / genotype analysis / 遺伝子 / 低音障害型難聴 / WFS1遺伝子 / 低温障害型感音難聴 / 位置的候補遺伝子解析 / 連鎖解析 / WFSI遺伝子 / 低音障害型感音難聴 / Cholesteatoma / Patulous eustachian tube / ET plug / Laser / Labyrinthine fistulae / 中耳真珠腫 / 真珠腫 / 耳管ピン / レーザー / 迷路瘻孔 / DNA mutation / Aging / Hereditary deafness / Endocochlear potential / Connexin-26 / knockout mice / 加齢 / Brn4 / 変異 / 老化マウス / ミトコンドリアDNA / 老人性難聴 / DNA異常 / 老化 / 内リンパ静止電位 / コネキシン26 / ノックアウトマウス / 再生医療 / 間葉系幹細胞 / オストマン脂肪体 / 脂肪細胞 / 解剖 / 側頭骨 / 中頭蓋窩法 / 聴神経腫瘍 / 内耳道 / 電気生理学的研究 / 聴力保存 Less
  • Research Projects

    (15 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (32 People)
  •  内耳におけるイオン輸送関連遺伝子の分子生物学的解析と難聴病態の解明Principal Investigator

    • Principal Investigator
      菊地 俊彦
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  The Stiffness Change of Conditioning Effect in Inner Hair Cells

    • Principal Investigator
      YOSHIDA Naohiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  耳管粘膜下における脂肪細胞の分化誘導-耳管開放症の根本的治療法の開発-

    • Principal Investigator
      小林 俊光
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Analysis of the potassium ion recycling mechanism in the cochlea : a challenge for the better understanding of the inner ear dysfunctionPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko, 千葉 敏彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Expression of voltage-gated potassium channels in the inner ear and herediatary deafness : molecular biological analysisPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Identification of causative gene for hereditary low-frequency sensorineural hearing loss

    • Principal Investigator
      SAKIHAMA Noriyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  中頭蓋窩法における内耳道の簡便同定法の開発―外耳道内照明法の研究―

    • Principal Investigator
      小林 俊光
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  進行性感音難聴モデル動物における内耳障害の多角的解析Principal Investigator

    • Principal Investigator
      菊地 俊彦
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  Analysis of the pathogenesis of the hereditary non syndromic deafness caused by mutations in connection genesPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  The New Treatments for the Complications of Middle Ear Cholesteatoma

    • Principal Investigator
      KOBAYASHI Toshimitsu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
  •  Genetics of Presbyacus's and its clinical application

    • Principal Investigator
      TAKASAKA Tomonori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Functional significance of the gap junctions in the ion transport mechanism in the cochlea -molecular biological analysisPrincipal Investigator

    • Principal Investigator
      KIKUCHI Toshihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Nagasaki University
      Tohoku University
  •  内耳手術における聴力保存に関する基礎的研究

    • Principal Investigator
      KOBAYASHI Toshimitsu
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Pathogenesis and Managements for Chronic Secretory Otitis Media.

    • Principal Investigator
      TAKASAKA Tomonori
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Serial section reconstruction of the guinea pig outer and inner hair cells as studied with a high-voltage electron microscope.

    • Principal Investigator
      SHINKAWA Hideichi
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Hirosaki University
      Tohoku University

All 2006 2005 Other

All Journal Article Book

  • [Book] 遺伝性難聴の病態解析(connexin遺伝子異常) 先端医療シリーズ35 耳鼻咽喉科・頭頸部外科学の最新医療2005

    • Author(s)
      菊地俊彦, 美野輪治
    • Total Pages
      5
    • Publisher
      先端医療技術研究所
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • [Book] Analysis of the hereditary deafness : connexin genemutations. (Kaga K., Komune S.(eds))(Senntanniryou Series 35 Jibiinnkouka)2005

    • Author(s)
      Kikuchi T., Minowa O.
    • Publisher
      Sentanniryou gijutu kennkyuujo, Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • [Journal Article] Gap Junctions and Cochlear Homeostasis.2006

    • Author(s)
      Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
    • Journal Title

      J.Membr.Bop. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • [Journal Article] Gap junctions and cochlear homeostasis.2006

    • Author(s)
      Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
    • Journal Title

      J.Membr Biol (in press)

    • Data Source
      KAKENHI-PROJECT-16591696
  • [Journal Article] Gap junctions and cochlear homeostasis.

    • Author(s)
      Zhao H.B., Kikuchi T., Ngezahayo A., White T.W.
    • Journal Title

      J. Membr Biol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591696
  • 1.  KOBAYASHI Toshimitsu (80133958)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  KAWASE Tetsuaki (50169728)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  TANAKA Fujinobu (00284688)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  YOSHIDA Naohiro (90291260)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  TAKASAKA Tomonori (80004646)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TSUKASAKI Naoki (70274660)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OSHIMA Takeshi (40241608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  IKEDA Katsuhisa (70159614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  WADA Hiroshi (30111264)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SHINKAWA Hideichi (90125584)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  高村 博光 (50281209)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  千葉 敏彦 (70280881)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  NAKAO Yoshiaki (40188884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SAKIHAMA Noriyuki (60264230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MATSUMOTO Naomichi (80325638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIURA Koh-ichiro (00304931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KATORI Yukio (20261620)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HOZAWA Koji (20199459)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SHIBAHARA Yoshihiro (70142940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SUZUKI Mamoru (10206534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  橋本 省 (20156285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  佐々木 豊 (30221279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  志賀 清人 (10187338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  堀井 明 (40249983)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  古川 徹 (30282122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  山内 大輔 (70361102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  神田 幸彦 (20264244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  末武 光子 (40183412)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  栗原 篤 (80192037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  鈴木 秀明 (20187751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  YAGINUMA Yuji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  八木沼 裕司
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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