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KOCHI Masato  河内 正人

ORCIDConnect your ORCID iD *help
Researcher Number 70178218
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2004: 熊本大, 助教授
2003 – 2004: 熊本大学, 大学院・医学薬学研究部, 助教授
1997 – 2002: 熊本大学, 医学部, 助教授
1996 – 1997: Kumamoto University School of Medicine Lecturer, 医学部, 講師
1992 – 1993: 熊本大学, 医学部, 講師 … More
1987 – 1991: Kumamoto Univ.Med.Sch.Hospital Neurosurg.Instructor, 医学部附属病院, 助手
1990: Kumamoto Univ. Hospital, Instructor Neurosurgery, 医学部・附属病院, 助手
1988: KUMAMOTO UNIVERSITY MEDICAL SCHOOL, NEUROSURGERY,ASSISTANT LECTURER, 医学部付属病院, 助手
1986: 熊本大学, 医学部附付病院, 助手 Less
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery / Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery / Cerebral neurosurgery / Biological Sciences
Keywords
Principal Investigator
悪性脳腫瘍 / MCP-1 / IL-12 / malignant glioma / グリオーマ / 髄腔内播種 / 悪性グリオーマ / monkey / clinical application / suicide gene … More / brain tumor / electro-gene therapy / 安全性 / 脳腫瘍モデル / 臨床応用 / 自殺遺伝子 / 脳腫瘍 / 遺伝子治療 / 電気穿孔法 / subarachnoid dissemination / radio-chemosensitivity / apoptosis / 放射線化学療法感受性 / アポトーシス / LIPOSOME / NITROSOUREAS / INTRATHECAL CHEMOTHERAPY / SUBARACHNOID DISSEMINATION / MALIGNANT GLIOMAS / ACNU / 髄腔内潅流化学療法 / 神経膠腫(グリオーマ) / 髄液腔内潅流療法 / リポソーム / BCNU / リボソーム / ニトロソウレア / 髄腔内化学療法 / E1Aプラスミド / 標的治療 / EGFレセプター / 膜型チロシンキナーゼ … More
Except Principal Investigator
グリオーマ / MCP-1 / Glioma / ケモカイン / サイトカイン / マクロファージ / 脳腫瘍 / promoter / gene therapy / monocyte / malignant glioma / glioma / 電気遺伝子療法 / 遺伝子治療 / CCR2 / 増殖因子 / 悪性脳腫瘍 / 生体内電気穿孔法 / 自殺遺伝子 / IL-12 / cloning / Macrophage / ADH / ACNU / BiP / hypoxia / ischemia / ER stress / CHOP / cytosine deaminase / 5-FU / 5-FC / HSV1yCD / methylation / luciferase / gene / NF2 / classification / prognosis / EGFR / p16 / p53 / gene analysis / gene regulation / EBP / C / Oct-1 / Angiogenesis / 抗癌剤 / プロモーター / 単球 / chemotherapy / drug delivery / MCP-1 receptor / Chemotherapy / Growth Factor / dissemination / PDGF / therapy / growth factor / combination electro-gene therapy / HS-tk / 浸潤 / chemokine / 免疫 / Drug-resistant / インターフェロン / 制癌剤 / 薬剤耐性 / 癌化学療法 / Calcineurin / カルモデュリン / グリコーゲン合成酵素 / カルシニュリン / 視床下部腫瘍 / FIBRONECTIN / ADHESIVE FACTOR / SIALIC ACID / CSF PERFUSION / DIAGNOSIS / CSF DISSEMINATION / BRAIN TUMOR / 核磁気共鳴 / 膜表面物質 / スフェロイド培養 / 癌細胞凝集因子 / アポ蛋白E / 転移 / 髄液腔内播種 / シアル酸 / 髄液腔 / 脳腫瘍転移 / apoptosis / Bip / 脳虚血 / 線条体 / 海馬 / アポトーシス / 小胞体ストレス / 脳梗塞 / Oncolytic virus / malignant brain tumor / Herpes virus vector / oncolytic virus / ヘルペスウィルスベクター / LOH 10 / 機能的解析 / 生存日数 / PTEN / LOH / 10番染色体 / glioblastoma / LOH10 / CT26 tumor / chemokine gene / suicide gene / electro-gene therapy / 受容体 / Macro phage / GST-fusion protein / anti-cancer drug / microsphere / Invasin / GST融合蛋白 / マイクロスフィアー / invasin / 遺伝子療法 / MCP-1レセプター / 転写因子 / リンパ球 / plasmid DNA / lac Z gene / brain tumor / in vivo electroporation / electro-genetherapy (EGT) / hMCP1 / MCP-1遺伝子 / human MCP-1遺伝子 / lacZ遺伝子 / プラスミドDNA / Fluocytometry / Dissemination / Trapidil / 臨床応用 / DT-A / Hsv-tk / 電気穿孔法 / TAT-GFP / C6グリオーマ細胞 / 髄腔内播種 / TAT-p16 / TAT-lacZ / TATペプチド融合蛋白 / ライブラリースクリーニング / EST / 接着分子 / クローニング / フラクタルカイン / medulloblastoma / ganglioglioma / neurocytoma / fractalkine / 遊走因子 / Cytokine / Immunity Less
  • Research Projects

    (26 results)
  • Co-Researchers

    (27 People)
  •  Role of ER-stress on ischemic neuronal cell death

    • Principal Investigator
      YANO Shigetoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  アデノウィルスの遺伝子産物E1A発現プラスミドを用いた悪性脳腫瘍の治療法の開発Principal Investigator

    • Principal Investigator
      河内 正人
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  Development of the gene therapy for the malignant brain tumor using the oncolytic herpes virus vector

    • Principal Investigator
      NAKAMURA Hideo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  生体内電気穿孔法を用いた電気遺伝子療法の臨床応用へ向けた安全性に関する研究

    • Principal Investigator
      生塩 之敬
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Research for clinical application of electro-gene therapy against malignant brain tumorPrincipal Investigator

    • Principal Investigator
      KOCHI Masato
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  固形癌に対する自殺遺伝子とサイトカイン遺伝子群を併用した複合電気遺伝子療法の開発

    • Principal Investigator
      生塩 之敬
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  悪性脳腫瘍の自殺遺伝子・複数サイトカイン遺伝子を用いた複合電気遺伝子療法の開発

    • Principal Investigator
      西 徹
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  シッピシグ・タグ付加レコンビナント蛋白質の髄液内投与と悪性脳腫瘍治療への応用

    • Principal Investigator
      生塩 之敬
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  Research for pathophysiology of subarachnoid dissemination of malignant brain tumorsPrincipal Investigator

    • Principal Investigator
      KOCHI Masato
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  CLASSIFICATION OF MALIGNANT GLIOMAS BY MOLECULAR GENETIC ANALYSIS TO DEVELOP RATIONAL THERAPY

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Role of NF2 tumor suppressor gene promoter in the tumorigenesis

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
      Kumamoto University
  •  脳腫瘍における模型ケモカインのクローニングと解析

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  Development of a method for combination electro-gene therapy using suicide gene and chemokine gene(s)

    • Principal Investigator
      NISHI Toru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Developement of a method for cancer treatment using invsin-conjugated microsphere

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Development plan of the new treatment for malignant glioma using Monocyte Chemoattrctant Protein-1

    • Principal Investigator
      KURATSU Jun-ichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagoshima University
      Kumamoto University
  •  Development of the Gene-missile therapy against human malignant gliomas using monocyte as a carrier.

    • Principal Investigator
      TAKESHIMA Hideo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  悪性グリオーマにおけるマクロファージ浸潤とその意義および臨床応用に向けて

    • Principal Investigator
      倉津 純一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  New approach for the treatment of glioblastomas.

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  DEVELOPMENT OF GENE TRANSFER METHOD FOR SOLID TUMORS USING IN VIVO ELECTROPORATION.

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  グリオーマにおける単球遊走因子の遺伝子発現とその調節機構

    • Principal Investigator
      倉津 純一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  INTRATHECAL CHEMOTHERAPY AGAINST SUBARACHNOID DISSEMINATION OF MALIGNANT BRAIN TUMORSPrincipal Investigator

    • Principal Investigator
      HAMADA Junichiro, 河内 正人
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  グリオーマにおける単球遊走因子の遺伝子発現とその調節機構

    • Principal Investigator
      KURATSU Jun-ichi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  A Study for New Approaches in the Treatment of Malignant Gliomas.

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Molecular Cell Biology of Drug-resistant Glioma and Treatment.

    • Principal Investigator
      USHIO Yukitaka
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  •  BIOLOGICAL SPECIALITY OF THE TUMOR CELL MEMBRANE IN RELATION TO THE MECHANISM OF BRAIN TUMOR INFILTRATION,DISSEMINATION AND METASTASIS- BASIC AND CLINICAL EXPERIMENT-

    • Principal Investigator
      MATSUKADO Yasuhiko
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Role of ADH to Central nervous system Function -With special Reference ot Ca ion-

    • Principal Investigator
      UEMURA Shozaburo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kumamoto University
  • 1.  USHIO Yukitaka (20028583)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 2.  NISHI Toru (00264309)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 0 results
  • 3.  KURATSU Jun-ichi (20145296)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 4.  TAKESHIMA Hideo (70244134)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 5.  MIHARA Masaki (00192352)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  UEMURA Shozaburo (00128258)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  SETO Hiroshi (60209848)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  YANO Shigetoshi (60332871)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  MORIOKA Motohiro (20295140)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  TAKADA Akira (10187966)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  NAGAHIRO Shinji (60145315)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  SAYA Hideyuki (80264282)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  GOTO Satoshi (50240916)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  HAMADA Junichiro (40253752)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  MATSUKADO Yasuhiko (30037337)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIOKA Susumu (00182725)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  児玉 万典 (60040581)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  NAKANO Masahiro (40002125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HIRANO Hirofumi (00264416)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YOKOYAMA Shunichi (90191519)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SAITO Yoshiki (50304994)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  NAKAMURA Hideo (30359963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KAI Yutaka (30322308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  MORI Masataka (40009650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  和田 伸一 (30094056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SUGIMOTO Yoshikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SAKATA Tsuneaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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