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Watanabe Kenji  渡辺 賢治

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WATANABE Kenji  渡辺 賢治

渡辺 賢治  ワタナベ ケンジ

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Researcher Number 70191757
Other IDs
Affiliation (Current) 2025: 横浜薬科大学, 薬学部, 特別招聘教授
Affiliation (based on the past Project Information) *help 2013 – 2014: 慶應義塾大学, 環境情報学部, 教授
2011 – 2012: 慶應義塾大学, 医学部, 准教授
2010: 慶應義塾大学, 医学部, 講師
2007 – 2009: Keio University, 医学部, 准教授
2005 – 2006: 慶應義塾大学, 医学部, 助教授 … More
2000: 社団法人北里研究所, 東洋医学総合研究所, 研究員
1999: 社団法人 北里研究所, 東洋医学総合研究所, 研究員
1998: (社)北里研究所, 東洋医学総合研究所, 研究員
1996: (社)北里研究所, 東洋医学総合研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
General internal medicine (including Psychosomatic medicine) / Virology
Except Principal Investigator
Bioinformatics/Life informatics / Medical sociology
Keywords
Principal Investigator
アレルギー / 抗生物質 / 腸内細菌 / 漢方薬 / toll like receptor 4 / ノックアウトマウス / ノックアウトマ / MyD88 / toll like receptor / インターフェロンα … More / 十全大補湯 / ヒートショック蛋白 / 1型インターフェロン / Toll like receptor / IgE / 腸内細菌叢 / 免疫寛容 / 制御性T細胞 / GeenChip / 遺伝子発現 / 胎児期 / 免疫 / 抗生剤 / マウス / T-RFLP / ヒートショックプロテイン / NF-κB / AP-1 / LTR / HIV-1 … More
Except Principal Investigator
遺伝子ネットワーク / hearing research / Contents of classical document / educational system / Oriental medicine_ / 大学医学部のネットワーク作り / データーベース / 夏期集中セミナー / 東洋医学の卒前・卒後教育 / 東洋医学の入門書 / 東洋医学に対する意識 / 東洋医学用語 / 東洋医学セミナー / 代替医療 / 韓医学 / 東洋医学 / 東洋医学の基盤整備 / 古典資料の目録 / アンケート調査 / 東洋医学の標準的教科書 / 東洋医学の基礎整備 / 東洋医学教育 / 遺伝子発現 / データ統合 / オミックス解析 / システム的解析 / トランスクリプトーム / オミクスデータ解析 / 漢方薬効 / システム数理解析 / Bayesiamネットワーク / 薬剤応答パスウェィ / ベトリネット / パスウェイ解析 / がん / 状態空間モデル / ペトリネット / ベイジアンネットワーク / パ スウェイ解析 / シミュレーション / 動的モデル / 薬剤応答パスウェイ Less
  • Research Projects

    (7 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (14 People)
  •  Omics Analysis and Systems Mathematical Science towards Understanding Kampo Efficacy

    • Principal Investigator
      IMOTO Seiya
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      The University of Tokyo
  •  Drug-response pathway analysis methods based on network analysis

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      The University of Tokyo
  •  Investigation of Kampo medicine mechanism against the infection via type 1 interferon producing cellsPrincipal Investigator

    • Principal Investigator
      WATANABE Kenji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Keio University
  •  Anti-allergic effect of Kampo medicine : a possible association with enteric microbiota and gastrointestinal immune systemPrincipal Investigator

    • Principal Investigator
      WATANABE Kenji
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Keio University
  •  漢方薬による腸内細菌叢の変化とアレルギー発症予防の機序解明Principal Investigator

    • Principal Investigator
      渡辺 賢治
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Keio University
  •  Fundamental research of educational system and method of Oriental medicine on 21st century in Japan

    • Principal Investigator
      HANAWA Toshihiko
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical sociology
    • Research Institution
      The Kitasato Institute
  •  HIVプロウィルス転写活性制御におけるAP-1の役割Principal Investigator

    • Principal Investigator
      渡辺 賢治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Virology
    • Research Institution
      Kitasato Institute

All 2014 2012 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Analysis of Questionnaire for Traditional Medicine and Development of Decision Support System2014

    • Author(s)
      Kotoe Katayama, Rui Yamaguchi, Seiya Imoto, Kenji Watanabe and Satoru Miyano
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2014 Issue: 1 Pages: 974139-974139

    • DOI

      10.1155/2014/974139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300111
  • [Journal Article] Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto : acceleration of IFN-αresponse via affecting the ISGF3-IRF7 signaling cascade2012

    • Author(s)
      Munakata K, Takashima K, Nishiyama M, Asano N, Mase A, Hioki K, Ohnishi Y, Yamamoto M, Watanabe K
    • Journal Title

      BMC Genomics

      Volume: 13 Pages: 30-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto : acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade2012

    • Author(s)
      Kaori Munakata, kiyoe Takashima, Mitsue Nishiyama, Naoko Asano, Akihito Mase, Kyoji Hioki, Yasuyuki Ohnishi, Masahiro Yamamoto, Kenji Watanabe
    • Journal Title

      BMC Genomics

      Volume: 13:30 Issue: 1

    • DOI

      10.1186/1471-2164-13-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] 漢方薬十全大補湯が大腸のIFN-alpha産生に及ぼす影響2010

    • Author(s)
      宗形佳織、渡辺賢治
    • Journal Title

      消化と吸収

      Volume: Vol.32 No.2 Pages: 185-188

    • NAID

      10027054642

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] 大腸におけるインターフェロンαの産生に対する十全大補湯の作用:MyD88、TLR4ノックアウトマウスを用いた解析2010

    • Author(s)
      皆川紗代、宗形佳織、渡辺賢治
    • Journal Title

      消化と吸収

      Volume: Vol.32 No.2 Pages: 181-184

    • NAID

      10027054636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] 大腸におけるインターフェロンαの産生に対する十全大補湯の作用: MyD88、TLR4ノックアウトマウスを用いた解析2010

    • Author(s)
      皆川紗代、宗形佳織、渡辺賢治
    • Journal Title

      消化と吸収

      Volume: Vol.32 No.2 Pages: 181-184

    • NAID

      10027054636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] Intestinal flora induces Cyp3a in the liver.2009

    • Author(s)
      Toda T, Saito N, Fujimoto A, Ikarashi N, Ito K, Yamamoto M, Ishige A, Watanabe K, Sugiyama K.
    • Journal Title

      Xenobiotica 39(4) :

      Pages: 323-334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Journal Article] Orengedokuto and berberine improve ingdomethacin-induced small intestinal inhury via adenosine2009

    • Author(s)
      Watanabe Y, Watanabe K, et.al
    • Journal Title

      J.Gastroenterol 44(5)

      Pages: 380-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] Intestinal flora induces the expression of Cy3pa in the liver2009

    • Author(s)
      Toda T, Watanabe K, et.al.
    • Journal Title

      Xenobiotica 39(4)

      Pages: 323-334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Journal Article] Intestinal flora induces Cyp3a in the liver2009

    • Author(s)
      Toda T, Saito N, Fujimoto A, Ikarashi N, Ito K, Yamamoto M, Ishige A, Watanabe K, Sugiyama K.
    • Journal Title

      Xenobiotica 39(4)

      Pages: 323-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Journal Article] Importance of the interferon-alpha system in murine large intestine indicated by microarray analysis of commensal bacteria-induced immunological changes.2008

    • Author(s)
      Munakata K, Yamamoto M, Anjiki N, Nishiyama M, Imamura S, Iizuka S, Takashima K, Ishige A, Hioki K, Ohnishi Y, Watanabe K.
    • Journal Title

      BMC Genomics 9

      Pages: 192-192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Journal Article] Importance of the interferon-alpha system in murine large intestine indicated by microarray analysis of commensal bacteria-induced immunological changes2008

    • Author(s)
      Munakata K, Yamamoto M, Anjiki N, Nishiyama M, Imamura S, Iizuka S, Takashima K, Ishige A, Hioki K, Ohnishi Y, Watanabe K.
    • Journal Title

      BMC Genomics 9

      Pages: 192-192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Journal Article] Effect of Herbal Medicine Juzentaihoto on Hepatic and Intestinal Heat Shock Gene Expression Requires Intestinal Microflora in the Mouse2007

    • Author(s)
      Kato M, Ishige A, Benno Y, Watanabe K, et al.
    • Journal Title

      World Journal of Gastroenterology (in press)

    • Data Source
      KAKENHI-PROJECT-17659206
  • [Journal Article] Identification of activated transcription factors from microarraygene expression data of Kampo medicine-treated mice2007

    • Author(s)
      Yamaguchi R, Yamamoto M, Imoto S, Nagasaki M, Yoshida R, Tsuiji K, Ishige A, Asou H, Watanabe K. Miyano S.
    • Journal Title

      Genome Informatics 18

      Pages: 118-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Journal Article] Effect of herbal medicine Juzentaihoto on hepatic and intestinal heat shock gene expression requires intestinal microfl ora in mouse2007

    • Author(s)
      Kato M, Ishige A, Anjiki N, Yamamoto M, Irie Y, Taniyama M, Kibe R, Oka J, Benno Y, Watanabe K.
    • Journal Title

      World J Gastroenterol 13

      Pages: 2289-2297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] 十全大補湯により誘導される大腸のIFNα産生細胞の解析2010

    • Author(s)
      宗形佳織、榎本成志、山本雅浩、渡辺賢治
    • Organizer
      和漢医薬学会学術大会
    • Place of Presentation
      京都薬科大学
    • Year and Date
      2010-08-29
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] Effect of Japanese herbal medicine(Kampo) on the survival of mice infected with influenza virus2010

    • Author(s)
      Munakata K, Yamamoto M, Watanabe K
    • Organizer
      ICCMR 2010
    • Place of Presentation
      Tromso, Norway
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 十全大補湯による大腸インターフェロンα産生促進の作用機序2009

    • Author(s)
      皆川紗代、宗形佳織、山本雅浩、渡辺賢治
    • Organizer
      第26回和漢医薬学会学術大会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 大腸におけるIFN alpha の産生調節機構の解明2009

    • Author(s)
      皆川紗代, 宗形佳織, 渡辺賢治
    • Organizer
      第40回日本消化吸収学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 漢方薬十全大補湯が大腸のIFN alpha 産生に及ぼす影響2009

    • Author(s)
      宗形佳織, 渡辺賢治
    • Organizer
      第40回日本消化吸収学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 免疫・アレルギー疾患の漢方治療2009

    • Author(s)
      渡辺賢治
    • Organizer
      第28回漢方免疫アレルギー研究会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 大腸におけるIFN alphaの産生調節機構の解明2009

    • Author(s)
      皆川紗代、宗形佳織、渡辺賢治
    • Organizer
      第40回日本消化吸収学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 免疫・アレルギー疾患の漢方治療2009

    • Author(s)
      渡辺賢治
    • Organizer
      第28回漢方免疫アレルギー研究会学術集
    • Place of Presentation
      東京
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] 漢方薬十全大補湯が大腸のIFN alpha産生に及ぼす影響2009

    • Author(s)
      宗形佳織、渡辺賢治
    • Organizer
      第40回日本消化吸収学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21390224
  • [Presentation] The effect of a herbal medicine (Juzen-taiho-to) in the large intestine implications for mechanism of prevention of infection2008

    • Author(s)
      Munakata K, Takashima K, Yamamoto M, Ishige A, Watanabe K.
    • Organizer
      3^<rd> International Congress on Complementary Medicine Research
    • Place of Presentation
      Sydney
    • Year and Date
      2008-03-30
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] IQIマウス大腸のtype 1インターフェロン産生における十全大補湯の影響2008

    • Author(s)
      宗形佳織、大竹英恵、小倉智幸、日置恭司、山本雅浩、石毛敦、渡辺賢治
    • Organizer
      第25回和漢医薬学会学術大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] IQIマウス大腸のtype 1インターフェロン産生における十全大補湯の影響2008

    • Author(s)
      宗形佳織, 大竹英恵, 小倉智幸, 日置恭司, 山本雅浩, 石毛敦, 渡辺賢治
    • Organizer
      第25回和漢医薬学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-08-30
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] Japanese herbal medicine orengedokuto prevents indomethacin-induced enteropathy : an analysis by microarray and metagene profiler2008

    • Author(s)
      Watanabe Y, Miura N, Fukutake M, Yamamoto M, Yamaguchi R, Miyano S, Ishige A, Takeda J, Watanabe K.
    • Organizer
      3^<rd> International Congress on Complementary Medicine Research
    • Place of Presentation
      Sydney
    • Year and Date
      2008-03-30
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] Balb/cにおける十全大補湯の免疫作用への働きとその作用機序の解明2007

    • Author(s)
      高嶋清江, 宗形佳織, 山本雅浩, 渡辺賢治
    • Organizer
      第24回和漢医薬学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] C57BL/6マウス大腸のtype 1インターフェロン産生における十全大補湯の影響2007

    • Author(s)
      宗形佳織, 高嶋清江, 山本雅浩, 渡辺賢治
    • Organizer
      第24回和漢医薬学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] サイエンスしての漢方療法2007

    • Author(s)
      渡辺賢治
    • Organizer
      第22回日本更年期医学会学術集会教育講演
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] C57BL/6マウス大腸のtype1インターフェロン産生における十全大補湯の影響2007

    • Author(s)
      宗形 佳織, 高嶋 清江, 山本 雅浩, 渡辺 賢治, ら
    • Organizer
      第24回和漢医薬学会大会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-19590701
  • [Presentation] Integrated understanding for Hochuekkito on microarray expression data

    • Author(s)
      Kotoe Katayama, Kaori Munakata, Katsuaki Dan, Rui Yamaguchi ,Seiya Imoto, Kenji Watanabe, Satoru Miyano
    • Organizer
      Pacific Symposium on Biocomputing
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2015-01-04 – 2015-01-08
    • Data Source
      KAKENHI-PROJECT-24300111
  • 1.  BENNO Yoshimi (40087599)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  YAMAMOTO Masahiro (10398604)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 3.  NAGASAKI Masao (90396862)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  IMOTO Seiya (10345027)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  WATANABE Yoko (70338169)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 6.  MIYANO Satoru (50128104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAMAGUCHI Rui (90380675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  GOTOH Noriko (10251448)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HANAWA Toshihiko (40164892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ITO Go (30232440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KOSOTO Hiroshi (90186693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MURANUSHI Akihiko (50239539)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KIM S-J (40260088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SOEDA Atsuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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