Tauchi Hiroshi 田内広

… Alternative Names

TAUCHI Hiroshi 田内広

田内広タウチヒロシ

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Researcher Number	70216597
Other IDs
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Affiliation (Current)	2025: 茨城大学, 基礎自然科学野, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 茨城大学, 理工学研究科(理学野), 教授 2004 – 2017: 茨城大学, 理学部, 教授 2008 – 2010: 茨城大学, 理学部・地球生命環境科学科, 教授 2007: 茨城大学理学部, 地球生命環境科学科, 教授 2006: 茨城大学, 理学部地球生命環境科学科, 教授 … More 2001 – 2003: IBARAKI Univ., Faculty of Science, Associate professor, 理学部, 助教授 1995 – 2000: 広島大学, 原爆放射能医学研究所, 助手 1993: 広島大学, 原爆放射能医学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Biological Sciences / 環境影響評価(含放射線生物学) / Basic Section 63020:Radiation influence-related / Risk sciences of radiation and chemicals Except Principal Investigator 環境影響評価(含放射線生物学) / Human genetics / Nuclear fusion studies / Risk sciences of radiation/Chemicals / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Nuclear engineering / Biological Sciences / Risk sciences of radiation and chemicals
Keywords	Principal Investigator DNA損傷修復 / 相同組換え / DNA修復 / 放射線影響 / 突然変異 / DNA repair / 遺伝子ノックアウト / 体細胞突然変異 / 放射線生物影響 / Gene targeting … More / Homologous recombination / 放射線感受性 / DNA損傷 / 放射線 / 発がん抑制 / 高発がん性遺伝病 / 遺伝子安定性 / 相同組換え修復 / 細胞周期 / 低線量放射線 / 低線量率影響 / 低線量率 / トリチウム / Somatic mutation / Biological effect of radiation / 突然変異誘発 / Genome instability- / Ionizing radiation / 染色体不安定性 / 電離放射線 / Gene knockout / Radiation sensitivity / 遺伝疾患 / 相同組み換え / 損傷修復 / 遺伝子 / タンパク質就職 / タンパク質修飾 / NBS1 / 修復 / 遺伝的安定性 / アポトーシス / 高発癌遺伝病 / 放射線生物学 / 線量率効果 / 中性子 … More Except Principal Investigator NBS1 / NBS / 放射線感受性 / dsb / ATM / AT / 電離放射線 / 放射線 / ポジショナルクローニング / Nbs1 / テロメア / Ataxia-telangiectasia / ナイミーヘン症候群 / Xrs2 / RBE / 相同組換え / SMC1 / DNA修復 / 放射線高感受性 / フォーカス / 染色体不安定性 / WRN / BRCA1 / Nijmegen syndrome / 毛細血管拡張性運動失調症 / 高発癌性遺伝病 / NBSI / p53 / ionizing radiation / トリチウム / Positional cloning / gene mutation / 遺伝子突然変異 / 非相同末端再結合 / DNA損傷 / 二重鎖切断 / DNA二重鎖切断 / ナイミーヘン染色体不安定症候群 / YACコンティグ / 放射線リスク / DNA修復モデル / 細胞周期 / BLQモデル / 放射線突然変異 / 相同組換え修復 / トリチウムの人体への影響 / 福島第一原子力発電所事故 / 生体濃縮 / 細胞生存率 / DNAへの蓄積 / 海洋放出 / 細胞核線量 / トリチウム汚染水 / 細胞核線量率 / 処理・処分 / アポトーシス / トリチウムチミジン / トリチウム水 / モンテカルロ / ヒト細胞 / 風評被害の最小化 / 生体中トリチウム濃度の迅速測定 / 生物影響 / 海洋放出処分 / トリチウム処理水 / focus / telomere / Radiation / 免疫不全 / 高発癌性 / Ku70 / Atm / ノックアウトマウス / Chromosomal instability / DNA double strand break / Homologous Recombination / Nijmegen Breakage Syndrome / シグナル伝達 / 細胞・組織 / がん / 遺伝子 / 染色体異常 / S期チェックポイント / Embryonic lethal / Model mouse / Gene targeting / Rodiation sensitivity / Cancer prone disease / Nbs 1 / 胎生致死 / モデルマウス / 遺伝子標的法 / Radiosensitivity / Cancer prone disorder / 減数分裂 / 8q21 / 染色体不安定症候群 / Nijmegen breakage症候群 / linkage analysis / YAC / ア-Tバリアント / p21 / MDM2 / AT-Fresno / 家系分析 / HPRT mutation / hybrid cells / tritium / 6-thioguanin resistance / a human X-chromosome / ホルミ-シス効果 / 遺伝的影響 / hprt遺伝子 / 染色体移入 / Cu炭素粒子線 / HPRT / 6-チオグアニン / ハイブリッド細胞 / HPRT変異 / ハイブリット細胞 / 6-TG耐性 / 高感度突然変異 / ヒトX染色体 / YAC contig / Homozygosity mapping / Founder effect / Chromosome transfer uia microcell / p53 tumor suppressor protein / Radiation sensitivity / Nijmegen breakage syndrome / 劣性遺伝病 / 8番染色体 / 遺伝子マッピング / ATバリアント / アタキシアテランジェクタシア / ヒト染色体微小核移入 / ホモ接合体マッピング / 始祖効果 / 染色体微小核移入 / p53がん制御蛋白 / ナイミ-ヘン染色体不安定症候群 / p-gal positive selection / plasmid vector / Radiation effect / lacZ gene / Ingeno mouse / transgenic mouse / P-gal選択法 / プラスミドベクター / 放射線影響 / lacZ / インジェノマウス / トランスジェニックマウス / 小頭症 / DNA複製 / DNA修復制御 / ナイメーヘン症候群 / RAD18ドメイン / ドメイン解析 / 損傷乗越えDNA合成 / クロマチン・リモデリング / ヌクレオチド除去修復 / クロスリンク / トポイソメレース阻害剤 / 多環芳香族炭化水素付加体 / 感興変異原 / DNA鎖架橋 / 紫外線 / H2AX リン酸化 / DNA 修復 / 環境変異原 / クロマチンリモデリング / H2Bユビキチン化 / 損傷乗り越え合成 / 環境変異原,NBS1 / H2AXリン酸化 / 複製阻害 / 機能的相補性 / A-Tバリアント / Xrs2遺伝子 / NBSI遺伝子 / 創始者ハプロタイプ / スフェロプラスト融合法 / 微小核移入法 / 連鎖解析候群 / マウス劣性遺伝病 / V(D)J組換え / DNA2重鎖切断 / DNA修復欠損 / マウス重症複合型免疫不全症 / scid / 免疫不全症 Less

DNA修復細胞集団の再構成に伴う低線量放射線リスクの上振れ
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Kyoto University
Analysis of mutation induction by low concentration tritiated waterPrincipal Investigator
- Principal Investigator
  
  Tauchi Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Ibaraki University
Tritium bioeffects research for establishing social consensus on the disposal of tritiated water by oceanic discharge
- Principal Investigator
  
  Torikai Yuji
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear engineering
- Research Institution
  Ibaraki University
Role of NBS1 C-terminal domain in genomic stability
- Principal Investigator
  
  Komatsu Kenshi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Analysis of radiation-induced DNA double strand break repair during cell cyclePrincipal Investigator
- Principal Investigator
  
  TAUCHI Hiroshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Ibaraki University
Analysis of the relationship between DNA double strand break repair pathway and mutagenesis in response to ionizing radiation by using novel assay systemsPrincipal Investigator
- Principal Investigator
  
  Tauchi Hiroshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Ibaraki University
新規細胞系樹立による放射線DNA損傷修復シグナルと突然変異の関係解明Principal Investigator
- Principal Investigator
  
  田内広
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Ibaraki University
DNA損傷に応答した修復遺伝子の修飾と発現制御による発がん抑制機構の解明Principal Investigator
- Principal Investigator
  
  田内広
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ibaraki University
Study on DNA repair mechanism and mutagenesis using novel cell linesPrincipal Investigator
- Principal Investigator
  
  TAUCHI Hiroshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Ibaraki University
Induction of DNA double strand break by environmental genotoxic and carcinogenic agents
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
ATP依存性プロテアーゼ系と共役したDNAータンパク質クロスリンク修復機構
- Principal Investigator
  
  井出博
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hiroshima University
DNA損傷修復遺伝子異常とアポトーシス制御機構Principal Investigator
- Principal Investigator
  
  田内広
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ibaraki University
発がん抑制に機能するDNA修復タンパクにおける相同組換え制御ドメインPrincipal Investigator
- Principal Investigator
  
  田内広
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ibaraki University
Analysis of radiation-induced somatic mutation by using a gene knockoutPrincipal Investigator
- Principal Investigator
  
  TAUCHI Hiroshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Ibaraki University
発がん抑制に機能するDNA修復タンパクにおける相同組換え活性ドメインPrincipal Investigator
- Principal Investigator
  
  田内広
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ibaraki University
Study on repair mechanism of DMA double-strand breaks induced by ionizing radiation using a gene targeting techniquePrincipal Investigator
- Principal Investigator
  
  TAUCHI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  IBARAKI UNIVERSITY
Cancersusceptibility disease Nijmegen Breakage Syndrome and the function of underlying gene.
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY
  Hiroshima University
Molecular mechanism for chromosome stability using Nbs1 knockout mice
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  HIROSHIMA UNIVERSITY
Role of NBS1 in Repair of DNA damage Induced by Ionizing RadiationPrincipal Investigator
- Principal Investigator
  
  TAUCHI Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  IBARAKI UNIVERSITY
  Hiroshima University
Generation of knockout mice for Nijmegen breakage syndrome gene, NBS1.
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
染色体8q21上の放射線誘発DNA二重鎖切断からの修復遺伝子のクローニング
- Principal Investigator
  
  小松賢志
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hiroshima University
Study on underlying gene of Nijmegen Breakage Syndrome
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
Complementation assisted positional cloning of the gene for AT variant.
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Hiroshima University
高発癌遺伝病ナイミ-ヘン染色体不安定症候群の原因遺伝子の単離
- Principal Investigator
  
  MATSUURA Shinya
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Development of (a human X-chromosome * hamster) hybrid cell assay system, which is sensitive to tritium exposure.
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  HIROSHIMA UNIVERSITY
Molecular study on Nijmegen breakage sybdrome
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
免疫不全症およびDNA修復欠損の原因遺伝子HYRCの特性と単離
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Research and development of transgenic mouse for biological effect assesment of tritium
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear fusion studies
- Research Institution
  HIROSHIMA UNIVERSITY
核分裂中性子における逆線量率効果の発生機序の解明に関する研究Principal Investigator
- Principal Investigator
  
  田内広
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hiroshima University

[Journal Article] Mechanistic insights into the survival curve of HeLa cells with a short shoulder and their S phase-specific sensitivity2023
- Author(s)
  Komatsu Kenshi、Tauchi Hiroshi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 65 Issue: 2 Pages: 256-258
- DOI
  10.1093/jrr/rrad097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19847
[Journal Article] Prediction of late adverse events in pelvic cancer patients receiving definitive radiotherapy using radiation-induced gamma-H2AX foci assay2023
- Author(s)
  Someya Masanori、Hasegawa Tomokazu、Nakamura Asako J、Tsuchiya Takaaki、Kitagawa Mio、Gocho Toshio、Mafune Sho、Ikeuchi Yutaro、Tauchi Hiroshi、Sakata Koh-ichi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 64 Issue: 6 Pages: 948-953
- DOI
  10.1093/jrr/rrad079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19847, KAKENHI-PROJECT-23K07161, KAKENHI-PROJECT-21K07648, KAKENHI-PROJECT-21K07680
[Journal Article] Dose and dose-rate dependence of DSB-type mutants induced by X-rays or tritium beta-rays: An approach using a hyper-sensitive system.2022
- Author(s)
  Nagashima H, Hayashi Y, Tanimoto, S, Tauchi H
- Journal Title
  
  Radiation Protection Dosimetry
  
  Volume: 198 Issue: 13-15 Pages: 1009-1013
- DOI
  10.1093/rpd/ncac036
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19847
[Journal Article] Health effects triggered by tritium: How do we get public understanding based on scientifically supported evidence?2021
- Author(s)
  Matsumoto H, Shimada Y, Nakamura AJ, Usami N, Ojima M, Kakinuma S, Shimada M, Sunaoshi M, Hirayama R, Tauchi H.
- Journal Title
  
  J Radiat Res
  
  Volume: in press Issue: 4 Pages: 1-1
- DOI
  10.1093/jrr/rrab029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03620, KAKENHI-PROJECT-19K12318
[Journal Article] Mitotic cells can repair DNA double-strand breaks via a homology-directed pathway2021
- Author(s)
  Sakamoto Yuki、Kokuta Tetsuya、Teshigahara Ai、Iijima Kenta、Kitao Hiroyuki、Takata Minoru、Tauchi Hiroshi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 62 Issue: 1 Pages: 25-33
- DOI
  10.1093/jrr/rraa095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12318
[Journal Article] Induction of somatic mutations by low concentrations of tritiated water (HTO): evidence for the possible existence of a dose-rate threshold2021
- Author(s)
  Nagashima Haruki、Hayashi Yuki、Sakamoto Yuki、Komatsu Kenshi、Tauchi Hiroshi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 62 Issue: 4 Pages: 582-589
- DOI
  10.1093/jrr/rrab022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12318
[Journal Article] Tritium Biology in Japan: A search for a new approach2018
- Author(s)
  Tauchi, H., Toyoshima-Sasatani, M., Nagashima, H., Shimura, T., Umata, T., Tachibana, A.
- Journal Title
  
  Fusion Engineering and Design
  
  Volume: 128 Pages: 28-32
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04629
[Journal Article] Induction of somatic mutations by low-dose X-rays: the challenge in recognizing radiation-induced events2017
- Author(s)
  Nagashima Haruki、Shiraishi Kumiko、Ohkawa Saori、Sakamoto Yuki、Komatsu Kenshi、Matsuura Shinya、Tachibana Akira、Tauchi Hiroshi
- Journal Title
  
  J Radiat Res
  
  Volume: 58 Issue: suppl_2 Pages: 1-7
- DOI
  10.1093/jrr/rrx053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-15H04321
[Journal Article] utations in the FHA-domain of ectopically expressed NBS1 lead to radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination2014
- Author(s)
  Ohara, M., Funyu, Y., Ebara, S., Sakamoto, Y., Seki, R., Iijima, K., Ohishi, A., Kobayashi, J., Komatsu, K., Tachibana, A., Tauchi, H.
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25550023
[Journal Article] Mutations in the FHA-domain of ectopically expressed NBS1 lead to Radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination2014
- Author(s)
  Maki Ohara, Yumi Funyu, Shunsuke Ebara, Yuki Sakamoto, Ryota Seki, Kenta Iijima, Akiko Ohishi, Junya Kobayashi, Kenshi Komatsu, Akira Tachibana, and Hiroshi Tauchi
- Journal Title
  
  J. Radiat. Res
  
  Volume: 55 Issue: 4 Pages: 690-698
- DOI
  10.1093/jrr/rru011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-24310038, KAKENHI-PROJECT-24510064, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25550023, KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20.2014
- Author(s)
  Oliveira DV, Kato A, Nakamura K, Ikura T, Okada M, Kobayashi J, Yanagihara H, Saito Y, Tauchi H, Komatsu K
- Journal Title
  
  J Cell Sci
  
  Volume: 127 Pages: 763-772
- DOI
  10.1242/jcs.135855
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131004, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-24310038, KAKENHI-PROJECT-24510070, KAKENHI-PUBLICLY-25112513, KAKENHI-PROJECT-25550025, KAKENHI-PROJECT-25550026, KAKENHI-PROJECT-26241013, KAKENHI-PROJECT-26550025
[Journal Article] Assessment of biological effect of tritiated water by using hypersensitive system2011
- Author(s)
  Tauchi, H., ほか
- Journal Title
  
  Fusion Science and Technology
  
  Volume: 60 Pages: 1173-1178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310033
[Journal Article] Regulation of homologous recombination by RNF20-dependent H2B ubiquitination2011
- Author(s)
  K.Nakamura, A.Kato, J.Kobayashi, H.Yanagihara, S.Sakamoto, D.V.N.P.Oliveira, M.Shimada, H.Tauchi, H.Suzuki, S.Tashiro, L.Zou, K.Komatsu.
- Journal Title
  
  Molecular Cell 41
  
  Pages: 515-628
- NAID
  130007000484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Gimeracil sensitizes cells to radiation via inhibition of homologous recombination.2010
- Author(s)
  Takagi, M., Sakata, K., Someya, M., Tauchi, H., Iijima, K., Matsumoto, Y., Torigoe, T., Takahashi, A., Hareyama, M., Fukushima, M.
- Journal Title
  
  Radiotherapy & Oncology 96
  
  Pages: 259-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance to DNA-protein crosslinks in mammalian cells.2009
- Author(s)
  Nakano T., Katafuchi A., Matsubara M., Terato H., Tsuboi T., Masuda, T., Tatsumoto M., Pack S.-P. Makino K., Croteau D.L., Van Houten B., Iijima K., Tauchi H., Ide H.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 27065-27076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance to DNA-protein crosslinks in mammalian cells2009
- Author(s)
  Nakano, T., Katafuchi, A., Matsubara, M., Terato, H., Tsuboi, T., Masuda, T., Tatsumoto, M., Pack, S.-P. Makino, K., Croteau, D. L., Van Houten, B., Iijima, K., Tauchi, H., Ide, H.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 27065-27076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value2009
- Author(s)
  Tauchi, H., Waku, H., Matumoto, E., Yara, S., Okumura, S., Iwata,Y., Komatsu, K., Frusawa, Y., Eguchi-Kasai, K., Tachibana, A.
- Journal Title
  
  J. Radiat. Res. 50
  
  Pages: 441-448
- NAID
  10025912698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value.2009
- Author(s)
  Tauchi, H., ほか
- Journal Title
  
  Journal of Radiation Research VOL.50
  
  Pages: 441-448
- NAID
  10025912698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1.2009
- Author(s)
  Kobayashi J, Tauchi H, Chen B, Bruma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K.
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages: 752-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value.2009
- Author(s)
  Tauchi H., Waku H., Matumoto E., Yara S., Okumura S., Iwata Y., Komatsu K., Frusawa Y., Eguchi-Kasai K., Tachibana A.
- Journal Title
  
  J.Radiat.Res. 50
  
  Pages: 441-448
- NAID
  10025912698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS12009
- Author(s)
  Kobayashi J, Tauchi H, Chen B, Bruma S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K
- Journal Title
  
  Biochem Biophys Res Commun. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value.2009
- Author(s)
  H.Tauchi, H.Waku, E.Matsumoto, S.Yara, S.Okumura, Y.Iwata, K.Komatsu, Y.Furusawa, K.Eguchi-Kasai, A.Tachibana.
- Journal Title
  
  J Radiat Res. 50
  
  Pages: 441-448
- NAID
  10025912698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Two major factors involved in the reverse dose-rate effect for somatic mutation induction are the cell cycle position and LET value2009
- Author(s)
  Tauchi H
- Journal Title
  
  J Radiat Res 50
  
  Pages: 441-448
- NAID
  10025912698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Current topics in DNA double-strand break repair.2009
- Author(s)
  Kobayashi J, Iwabuchi K, Miyagawa K, Sonoda E, Suzuki K, Takata M, Tauchi H.
- Journal Title
  
  J Radiat Res 49
  
  Pages: 93-103
- NAID
  110006633651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 regulates a novel apoptotic pathway through Bax activation.2008
- Author(s)
  Iijima K, Muranaka C, Kobayashi J, Sakamoto S, Komatsu K, Matsuura S, Kubota N, Tauchi H.
- Journal Title
  
  DNA Repair 7
  
  Pages: 1705-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC1.2008
- Author(s)
  Antoccia A, Sakamoto S, Matsuura S, Tauchi H, Komatsu K.
- Journal Title
  
  Radiat Res. 170
  
  Pages: 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Rapid myeloid recovery as a possible mechanism of whole-body radioadaptive response.2008
- Author(s)
  Ohtsuka K., Koana T., Tomita M., Ogata H., Tauchi H.
- Journal Title
  
  Radiat.Res. 170
  
  Pages: 307-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Rapid myeloid recovery as a possible mechanism of whole-body radioadaptive response.2008
- Author(s)
  Ohtsuka, K., Koana, T., Tomita, M., Ogata, H., Tauchi, H.
- Journal Title
  
  Radiation Research 170
  
  Pages: 307-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Dancing on damaged chromatin : Functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage2008
- Author(s)
  Iijima, K., Ohara, M., Seki, R., Tauchi, H.
- Journal Title
  
  J. Radiat. Res. 49
  
  Pages: 451-464
- NAID
  110006935551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] NBS1 regulates a novel apoptotic pathway through Bax activation.2008
- Author(s)
  Iijima K., Muranaka C., Kobayashi J., Sakamoto S., Komatsu K., Matsuura S., Kubota N., Tauchi H.
- Journal Title
  
  DNA Repair 7
  
  Pages: 1705-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] NBS1 regulates a novel apoptotic pathway through Bax activation2008
- Author(s)
  Iijima, K., Muranaka, C., Kobayashi, J., Sakamoto, S., Komatsu, K., Matsuura, S., Kubota, N., Tauchi, H.
- Journal Title
  
  DNA Repair 7
  
  Pages: 1705-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Dancing on damaged chromatin : Functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage.2008
- Author(s)
  Iijima K., Ohara M., Seki R., Tauchi H.
- Journal Title
  
  J.Radiat.Res. 49
  
  Pages: 451-464
- NAID
  110006935551
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Dancing on damaged chromatin : Functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage.2008
- Author(s)
  Iijima, K., Ohara, M., Seki, R., Tauchi, H.
- Journal Title
  
  Journal of Radiation Reseaeach 49
  
  Pages: 451-464
- NAID
  110006935551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC12008
- Author(s)
  Antoccia A, Sakamoto S, Matsuura S, Tauchi H, Komatsu K
- Journal Title
  
  Radiat Res 170
  
  Pages: 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients.2007
- Author(s)
  Someya M., Sakata K., Matsumoto Y., Tauchi H., Narimatsu H., Hareyama M.
- Journal Title
  
  Oncology Report 18
  
  Pages: 873-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Characterization of the plant homolog of Nijmegen breakage syndrome 1: involvem ent in DNA repair and recombination2007
- Author(s)
  Akutsu, N.・Iijima, K.・Hinata, T.・Tauchi, H
- Journal Title
  
  Biochemical and Biophysical Research Communications 353
  
  Pages: 394-398
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions2007
- Author(s)
  Sakamoto S., Iijima K., Mochizuki D., Nakamura K., Teshigawara K., Kobayashi J., Matsuura S., Tauchi H., Komatsu K.
- Journal Title
  
  Oncogene 26
  
  Pages: 6002-9
- NAID
  130007001459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] TopBP1 associates with NBS1 and is involved in homologous recombination repair.2007
- Author(s)
  Morisima.K., Sakamoto.S., Kobayashi.J., Izumi.H., Suda.T., Matsumoto.Y., Tauchi.H., Ide.H., Komatsu K.Matsuura.S.
- Journal Title
  
  Biochem Biophys Res Commun. 362
  
  Pages: 872-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions.2007
- Author(s)
  Sakamoto S., Iijima K., Mochizuki D., Nakamura K., Teshigawara K., Kobayashi J., Matsuura S., Tauchi H., Komatsu K.
- Journal Title
  
  Oncogene 26
  
  Pages: 6002-6009
- NAID
  130007001459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions.2007
- Author(s)
  Sakamoto.S., Iijima.K., Mochizuki.D., Nakamura.K., Teshigawara.K., Kobayashi.J., Matsuura.S., Tauchi.H.Komatsu K.
- Journal Title
  
  Oncogene. 26
  
  Pages: 6002-6009
- NAID
  130007001459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Characterization of the plant homolog of Nijmegen breakage syndrome 1 : involvement in DNA repair and recombination.2007
- Author(s)
  Akutsu, N., Iijima, K., Hinata, T., Tauchi, H.
- Journal Title
  
  Biochemical and Biophysical Research Communications 393
  
  Pages: 394-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Characterization of the plant homolog on Nijmegen breakage syndrome 1 : involvement in DNA repair and recombination2007
- Author(s)
  Akutsu, N., Iijima, K., Hinata, T, Tauchi, H.
- Journal Title
  
  Biochemical and Biophysical Research Communications 353
  
  Pages: 394-398
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients.2007
- Author(s)
  Someya, M., Sakata, K., Matsumoto, Y., Tauchi, H., Narimatsu, H., Hareyama, M.
- Journal Title
  
  Oncology Report 18
  
  Pages: 873-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] TopBP1 associates with NBS1 and is involved in homologous recombination repair.2007
- Author(s)
  Morishima K., Sakamoto S., Kobayashi J, Izumi H., Suda T., Matsumoto Y., Tauchi H., Ide H., Komatsu K., Matsuura S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 362
  
  Pages: 872-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310035
[Journal Article] Monoallelic BUB1B Mutations and Defective Mitotic-Spindle Checkpoint in Seven Families With Premature Chromatid Separation (PCS) Syndrome.2006
- Author(s)
  S.Matsuura, Y.Matsumoto, K.Morishima, H.Izumi, H.Matsumoto, E.Ito, K.Tsutsui, J.Kobayashi, H.Tauchi, Y.Kajiwara, S.Hama, K.Kurisu, H.Tahara, M.Oshimura, K.Komatsu, Tatsuro Ikeuchi, Tadashi Kajii.
- Journal Title
  
  Amer J Med Genet. 140(4)
  
  Pages: 358-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] ATM Activation by a Sulfhydryl-Reactive Inflammatory Cyclopentenone Prostaglandin.2006
- Author(s)
  M.Kobayashi, H.Ono, K.Mihara, H.Tauchi, K.Komatsu, H.Shimizu, K.Uchida, K.Yamamoto.
- Journal Title
  
  Genes Cells 11(7)
  
  Pages: 779-789
- NAID
  120006345302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Activation of Antioxidative Enzymes Induced by Low-Dose-Rate Whole-Body gamma Irradiation : Adaptive Response in Terma of Initial DNA Damage2006
- Author(s)
  Otsuka, K., Koana, T., Tauchi, H., Sakai, K.
- Journal Title
  
  Radiation Research 166
  
  Pages: 474-478
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Association of Ionizing Radiation-Induced Foci of NBSI with Chromosomal Instabi lity and Brest Cancer Susceptibility2006
- Author(s)
  Someya, M.・Sakata, K.・Tauchi, H (他5名)
- Journal Title
  
  Radiation Research 166
  
  Pages: 575-582
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Association of Ionizing Radiation-Induced Foci of NBS1 with Chromosomal Instability and Breast Cancer Susceptibility2006
- Author(s)
  Someya, M., Sakata, K., Tauchi. H., et. al.
- Journal Title
  
  Radiation Research 166
  
  Pages: 575-582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Association of Ionizing Radiation-Induced Foci of NBS1 with Chromosomal Instability and Breast Cancer Susceptibility.2006
- Author(s)
  M.Someya, K.Sakata, H.Tauchi, Y.Matsumoto, A.Nakamura, K.Komatsu, M.Hareyama.
- Journal Title
  
  Radiation Research. 166
  
  Pages: 575-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] Activation of Antioxidative Enzymes Induced by Low-Dose-Rate Whole-Body gamma Irradiation: Adaptive Response in Terms of Initial DNA Damage2006
- Author(s)
  Otsuka, K.・Koana, T.・Tauchi, H.・Sakai, K.
- Journal Title
  
  Radiation Research 166
  
  Pages: 474-478
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Activation of Antioxidative Enzymes Induced by Low-Dose-Rate Whole-Body gamma Irradiation : Adaptive Response in Terms of Initial DNA Damage.2006
- Author(s)
  Otsuka, K., Koana, T., Tauchi, H., Sakai, K.
- Journal Title
  
  Radiation Reserch 166
  
  Pages: 474-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] ATM activation by a sulfhydryl-reactive inflammatory cyclopentenone prostaglandin2006
- Author(s)
  Kobayashi, M., Ono, H., Mihara, K., Tauchi, H.(他5名)
- Journal Title
  
  Genes to Cells 11
  
  Pages: 779-789
- NAID
  120006345302
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Association of Ionizing Radiation-Induced Foci of NBS1 with Chromosomal Instability and Breast Cancer Susceptibility2006
- Author(s)
  Someya, M., Sakata, K., Tauchi, H(他5名)
- Journal Title
  
  Radiation Research 166
  
  Pages: 575-582
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] ATM activation by a sulfhydryl-reacive inflammatory cyclopentenone prostaglandin2006
- Author(s)
  Kobayashi, M., Ono, H., Mihara, K., Tauchi, H, et. al.
- Journal Title
  
  Genes to Cells 11
  
  Pages: 779-789
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] ATM activaion by a sulfhydry1-reactive infalmmatory cyclopentenone prostagland in2006
- Author(s)
  Kobayashi, M.・Ono, H.・Mihara, K.・Tauchi, H (他5名)
- Journal Title
  
  Genes to Cells 11
  
  Pages: 779-789
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Activation of Antioxidative Enzymes Induced by Low-Dose-Rate Whole-Body gamma Irradiation : Adaptive Response in Terms of Initial DNA Damage2006
- Author(s)
  Otsuka, K., Koana, T., Tauchi. H., Sakai, K.
- Journal Title
  
  Radiation Research 166
  
  Pages: 474-478
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Characterization of the plant homolog of Nijmegen breakage syndrome 1 : involvement in DNA repair nad recombination2006
- Author(s)
  Akutsu, N., Iijima, K., Hinata, T. Tauchi, H
- Journal Title
  
  Biochemical and Biophysical Research Communications 353
  
  Pages: 394-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Nijmegen Breakage Syndrome and Functions of the Responsible Protein, NBS1.2006
- Author(s)
  Antoccia, J.Kobayashi, H.Tauchi, S.Matsuura, K.Komatsu.
- Journal Title
  
  Genome Dyn.Basel, Karger. 1
  
  Pages: 191-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101002
[Journal Article] The Nijmegen breakage syndrome gene and its role in genome stability2004
- Author(s)
  Iijima, K., Komatsu, K., Matsuura, S., Tauchi. H
- Journal Title
  
  Chromosoma 113
  
  Pages: 53-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] The Nijmegen breakage syndrome gene and its role in genome stab ility2004
- Author(s)
  Iijima, K.・Komatsu, K.・Matsuura, S.・Tauchi, H
- Journal Title
  
  Chromosoma 113
  
  Pages: 53-61
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16310035
[Journal Article] Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells2002
- Author(s)
  H.Tauchi
- Journal Title
  
  Nature 420
  
  Pages: 93-98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213087
[Journal Article] Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells2002
- Author(s)
  H.Tauchi, et al.
- Journal Title
  
  Nature 420
  
  Pages: 93-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213087
[Journal Article] The FHA domain of NBS1 is essential for nuclear foci formation after irradiation, but not essential for hRAD50/hMRE11/NBS1 complex DNA Repair activity.2001
- Author(s)
  H.Tauchi, et al.
- Journal Title
  
  J.Biol.Chem. 276
  
  Pages: 12-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213087
[Journal Article] The FHA domain of NBS1 is essential for nuclear foci formation after irradiation, but not essential for hRAD50/hMRE11/NBS1 complex DNA repair activity2001
- Author(s)
  H.Tauchi
- Journal Title
  
  J.Biol.Chem. 276
  
  Pages: 12-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213087
[Presentation] A hyper-sensitive system for analysis of mutation induction by low dose or low dose-rate radiations: Comparison between HTO and gamma-rays2024
- Author(s)
  Tauchi, H. Nagashima H., Myodo T., Tanimoto S., Sakamoto Y., Miyamoto T., Matsuura S
- Organizer
  Biological Effects & Application of Radiation (BEAR2024), Tokyo, 2024.3.15-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19847
[Presentation] ゲノム編集技術を用いた突然変異高感度検出系の改良2023
- Author(s)
  明道友希、谷本早紀、長島明輝、坂本裕貴、坪田一希、宮本達雄、松浦伸也、田内　広
- Organizer
  日本放射線影響学会第66回大会（東京）
- Data Source
  KAKENHI-PROJECT-22K19847
[Presentation] Effect of PI3-kinase inhibitors on DNA double strand break repair pathways: An approach using a site specific DSB induction system.2023
- Author(s)
  Myodo T, Sakamoto Y, Kobayashi H, Iijima K, Satou K, Komatsu K, Matsuura S, Tauchi H
- Organizer
  International Symposium on Natural and Artificial Radiation Exposures and Radiological Protection Studies, Hirosaki, 2023.9.19-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19847
[Presentation] 部位特異的DNA損傷導入系を用いたDNA二本鎖切断修復に影響する諸要因の解析2022
- Author(s)
  明道友希、坂本裕貴、小林穂波、種田旭将、名倉莊一郎、飯島健太、小松賢志、松浦伸也、田内　広
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-22K19847
[Presentation] Dose and Dose-rate dependence of radiation-induced mutation: An approach using a hyper-sensitive cell system.2022
- Author(s)
  Nagashima　H., Hayashi Y., Tanimoto S., Shiraishi K., Sakamoto Y., Tauchi H.
- Organizer
  The 6th International Symposium of the Network-type Joint Usage/ Research Center for Radiation Disaster Medical Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12318
[Presentation] ヒト染色体移入ハムスター細胞を用いた放射線誘発体細胞突然変異の線量・線量率依存性解析2021
- Author(s)
  長島明輝、林雄樹、谷本早紀、白石久美子、小松賢志、田内　広
- Organizer
  日本放射線影響学会第64回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K12318
[Presentation] 様々な線量のX 線により誘発された突然変異体の変異スペクトル解析2021
- Author(s)
  谷本早紀、長島明輝、林雄樹、細江一希、白石久美子、小松賢志、田内広
- Organizer
  日本放射線影響学会第64回大会
- Data Source
  KAKENHI-PROJECT-19K12318
[Presentation] Analysis of Dose and Dose-rate dependence of Radiation-Type mutation induced by tritiated water: An approach using a hyper-sensitive cell system2021
- Author(s)
  Nagashima H., Hayashi Y., Tanimoto S., Shiraishi K., Sakamoto Y., Tauchi H.
- Organizer
  IES International Symposium on“Environmental Dynamics of Radionuclides and Biological Effects of Low Dose-Rate Radiation”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12318
[Presentation] 低濃度トリチウム水による体細胞突然変異体の変異スペクトル解析2020
- Author(s)
  長島明輝、林雄樹、細江一稀、白石久美子、大川沙織、小松賢志、立花　章、田内　広
- Organizer
  日本放射線影響学会第63回大会
- Data Source
  KAKENHI-PROJECT-19K12318
[Presentation] 高感度検出系を用いたトリチウム水による体細胞突然変異体の解析2019
- Author(s)
  長島　明輝、林　雄樹、細江一稀、白石久美子、大川沙織、小松賢志、立花　章、田内　広
- Organizer
  日本放射線影響学会第62回大会
- Data Source
  KAKENHI-PROJECT-19K12318
[Presentation] An experimental approach for analysis of biological effect of low dose radiation and factors affecting DSB repair fidelity2015
- Author(s)
  Hiroshi Tauchi
- Organizer
  30th RBC-NIRS International Symposium
- Place of Presentation
  京都市
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] Function of NBS1 protein in the pathways responding to DNA double strand breaks induced by ionizing radiation2015
- Author(s)
  Tauchi, H.
- Organizer
  The 12th International Workshop on Microbeam Probes of Cellular Radiation Response
- Place of Presentation
  敦賀
- Year and Date
  2015-05-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] 部位特異的 DNA 二重鎖切断により誘発される体細胞突然変異の解析2015
- Author(s)
  坂本敬祥，小林穂波, 小林健太, 本田千明, 飯島健太, 小林純也，小松賢志，立花章, 田内広
- Organizer
  日本放射線影響学会ワークショップ
- Place of Presentation
  富山
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] Cell cycle dependence for the efficiency of homology-directed repair of DNA double strand break2015
- Author(s)
  Hiroshi Tauchi
- Organizer
  広島大学原爆放射線医科学研究所国際シンポジウム
- Place of Presentation
  広島市
- Year and Date
  2015-03-02
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] Analysis of mutation spectrum induced by a site specific DNA double strand break.2015
- Author(s)
  Sakamoto, K., Kobayashi, H., Kobayashi, K., Honda, C., Iijima, K., kobayashi, J., Komatsu, K., Tachiban, A., Tauchi, H.
- Organizer
  15th International Congress of Radiation Research (ICRR2015)
- Place of Presentation
  京都
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] An experimental approach for analysis of biological effect of low dose radiation and factors affecting DSB repair fidelity2015
- Author(s)
  Hiroshi Tauchi
- Organizer
  30th RBC-NIRS International Symposium
- Place of Presentation
  京都市
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-25550023
[Presentation] 部位特異的DNA二重鎖切断によって誘発された体細胞突然変異の解析2014
- Author(s)
  小林穂波、小林健太、本田千明、立花　章、田内　広
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島市
- Year and Date
  2014-10-01
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] 相同組換え修復の細胞周期依存性解析2014
- Author(s)
  坂本裕貴、大川沙織、穀田哲也、勅使河原愛、飯島健太、高田　穣、小松賢志、田内　広
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島市
- Year and Date
  2014-10-01
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] 相同組換え修復の細胞周期依存性解析2014
- Author(s)
  坂本裕貴、大川沙織、穀田哲也、勅使河原愛、飯島健太、高田　穣、小松賢志、田内　広
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01
- Data Source
  KAKENHI-PROJECT-25550023
[Presentation] 細胞周期とNBS1機能がDNA二重鎖切断修復効率と精度に与える影響2014
- Author(s)
  田内　広、坂本裕貴、穀田哲也、大川沙織、小林健太、小林純也、飯島健太、小松賢志
- Organizer
  第37回日本分子生物学会年会　ワークショップ
- Place of Presentation
  横浜市
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] Kinetics of Radiation-Induced DNA Double Strand Break Rejoining in DNA Repair Deficient Cells2013
- Author(s)
  Hiroshi Tauchi
- Organizer
  広島大学原爆放射線医科学研究所国際シンポジウム
- Place of Presentation
  広島市
- Year and Date
  2013-02-12
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] 高感度検出系を用いた放射線感受性修飾効果の解析2012
- Author(s)
  田内広
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台市(招待講演)
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] Analysis of cell cycle dependency of DNA double-strand break repair by homolo gous recombination2012
- Author(s)
  穀田哲也、田内広
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] DNA二重鎖切断の修復機構と放射線発がん2012
- Author(s)
  田内広, ほか
- Organizer
  第11回分子予防環境医学研究会
- Place of Presentation
  倉敷市(招待講演)
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PROJECT-22310033
[Presentation] Nbsl/Ku70二重欠損細胞のDNA複製阻害剤感受性2012
- Author(s)
  大原麻希、田内広
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台市
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] 体細胞突然変異の逆線量率効果におけるLET依存性2010
- Author(s)
  田内広., ほか
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22310033
[Presentation] DNA損傷修復機構と発がん・がん放射線治療2010
- Author(s)
  田内広
- Organizer
  第49回日本医学放射線学会生物部会学術大会
- Place of Presentation
  札幌
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-22310033
[Presentation] Functional relationship between Nbsl and Ku70 in cellular responses to DNA damage2010
- Author(s)
  Tauchi, H., ほか
- Organizer
  Annual Meeting of the Radiation Research Society
- Place of Presentation
  Maui, HI, USA
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22310033
[Presentation] Post-translational modification of NBS1 regulates apoptosis induction in response to DNA damage2009
- Author(s)
  Tauchi, H.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] Post-translational modification of NBS1 regulates apoptosis induction in response to DNA damage.2009
- Author(s)
  田内広
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] DNA損傷応答におけるNBS1とKu70の相互作用2009
- Author(s)
  田内広
- Organizer
  日本放射線影響学会第52開大会
- Place of Presentation
  広島市
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20012006
[Presentation] Post-translational modification of NBS1 regulates apoptosis induction in response to DNA damage.2009
- Author(s)
  田内広
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] DNA修復タンパクNBS1とKu70の相互作用2009
- Author(s)
  田内広
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] DNA修復タンパクNBS1とKu70の相互作用2009
- Author(s)
  田内広
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1が制御する新規のDNA損傷誘発アポトーシス経路2008
- Author(s)
  田内広
- Organizer
  日本分子生物学会・生化学会合同年会BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1が制御する新規のDNA損傷誘発アポトーシス経路2008
- Author(s)
  田内広
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] A novel apoptosis pathway through the activation of Bax by NBS12008
- Author(s)
  田内広
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20012006
[Presentation] Interaction Between NBS1 and Ku70 Regulates Apoptosis Induction by Radiation.2008
- Author(s)
  田内広
- Organizer
  International Workshop on DNA damage
- Place of Presentation
  Fukushima
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] Interaction Between NBS1 and Ku70 Regulates Apoptosis Induction by Radiation2008
- Author(s)
  Tauchi, H.
- Organizer
  International Workshop on DNA damage
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1 regulates the induction of apoptosis following radiation damage to DNA2007
- Author(s)
  Tauchi, H.
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1 regulates the induction of apoptosis following radiation damage to DNA.2007
- Author(s)
  田内広
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1によるp53非依存的な放射線誘発アポトーシス制御の機構2007
- Author(s)
  飯島健太、村中千寿子、小林純也、坂本修一、小松賢志、田内広
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1によるBax活性化を通じたDNA損傷誘発アポトーシスの制御2007
- Author(s)
  田内広
- Organizer
  日本分子生物学会・生化学会合同年会ワークショップ
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1によるBax活性化を通じたDNA損傷誘発アポトーシスの制御2007
- Author(s)
  田内広.
- Organizer
  日本分子生物学会・生化学会合同年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19310035
[Presentation] NBS1 regulates DNA-damage induced apoptosis independent of p532006
- Author(s)
  Tauchi, H
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Presentation] NBS1 regulates DNA-damage induced apoptosis independent of p532006
- Author(s)
  Tauchi, H
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Presentation] Human NBS1 regulates homology directed DNA repair through its N-terminal conserved domain2005
- Author(s)
  Tauchi, H
- Organizer
  Benzon Symposium No. 42, Cellular Responses to DNA Damage
- Place of Presentation
  Copenhagen, Denmark
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Presentation] Human NBS1 regulates homology directed DNA repair through its N-terminal conserved domain2005
- Author(s)
  Tauchi, H.
- Organizer
  Benzon Symposium No.42, Cellular Responses to DNA Damage
- Place of Presentation
  コペンハーゲン
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310035
[Presentation] DNA二本鎖切断修復タンパク質欠損細胞のDNA複製阻害剤感受性
- Author(s)
  大原麻希、阿部紘子、田中　彩、井坂早央里、戸松静香、高田　穣、立花　章、　田内　広
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] DNA損傷修復関連タンパクによるアポトーシス制御の二面性
- Author(s)
  田内　広、大原麻希、田中　彩、飯島健太、高田　穣、小林純也、小松賢志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Invited
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] 人工ヌクレアーゼによって誘発した部位特異的DSBによる体細胞突然変異
- Author(s)
  本田千明、小林健太、宮本智弘、大原麻希、立花　章、田内　広
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-24310038
[Presentation] DNA二重鎖切断修復欠損細胞におけるATM阻害の影響
- Author(s)
  坂本裕貴、深作直子、阿部紘子、田中　彩、戸松静香、大原麻希、高田　穣、小松賢志、立花　章、田内　広
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-25550023
[Presentation] Modification of camptothecin sensitivity by PARP inhibitor in DNA double strand break repair deficient cell lines
- Author(s)
  Ohara, M, Tanaka, A., Isaka, S., Tomatsu, S., Takata. M., Komatsu, K., Tatibana, A., Tauchi, H
- Organizer
  広島大学原爆放射線医科学研究所国際シンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24310038

1. KOMATSU Kenshi (80124577)

# of Collaborated Projects: 15 results

# of Collaborated Products: 19 results
2. MATSUURA Shinya (90274133)

# of Collaborated Projects: 13 results

# of Collaborated Products: 11 results
3. KATO Akihiro (70423051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. ENDO Satoru (90243609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHINOHARA Miki (80335687)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 小林純也 (30301302)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. SMEETS Domin

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YAGI Takasi (80182301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MORISIMA Kenichi (00363078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. ONO Tetsuya (00107509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAKAMOTO Shuichi (60346070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Torikai Yuji (80313592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 丹羽太貫 (80093293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 槌田謙 (80397570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 井出博 (30223126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 寺東宏明 (00243543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 趙慶利 (90313593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 庄司美樹 (30361950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 井原誠 (60175213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. DOMINIQUE Sm

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. CORRY Weemae

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. WEEMAES Corry

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SMEETS Dominique

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. WEEMAES Corr

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HEUVEL Vande

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. WEEMACS Corr

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. HIRAYAMA Ryoichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 松本英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 青田聖恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 井倉毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tauchi Hiroshi 田内 広

TAUCHI Hiroshi 田内 広

田内 広 タウチ ヒロシ

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Analysis of mutation induction by low concentration tritiated waterPrincipal Investigator

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Analysis of radiation-induced DNA double strand break repair during cell cyclePrincipal Investigator

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Analysis of the relationship between DNA double strand break repair pathway and mutagenesis in response to ionizing radiation by using novel assay systemsPrincipal Investigator

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新規細胞系樹立による放射線DNA損傷修復シグナルと突然変異の関係解明Principal Investigator

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DNA損傷に応答した修復遺伝子の修飾と発現制御による発がん抑制機構の解明Principal Investigator

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Study on DNA repair mechanism and mutagenesis using novel cell linesPrincipal Investigator

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DNA損傷修復遺伝子異常とアポトーシス制御機構Principal Investigator

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発がん抑制に機能するDNA修復タンパクにおける相同組換え制御ドメインPrincipal Investigator

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Analysis of radiation-induced somatic mutation by using a gene knockoutPrincipal Investigator

Tauchi Hiroshi 田内広

TAUCHI Hiroshi 田内広

田内広タウチヒロシ