• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Hirasawa Akira  平澤 明

… Alternative Names

平澤 明  ヒラサワ アキラ

HIRASAWA Akira  平澤 明

Less
Researcher Number 70242633
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-5692-805X
External Links
Affiliation (Current) 2025: 京都大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help 2023: 京都大学, 薬学研究科, 准教授
2018 – 2021: 京都大学, 薬学研究科, 准教授
2016: 京都大学, 大学院・薬学研究科, 准教授
2011 – 2012: 京都大学, 大学院・薬学研究科, 准教授
2011 – 2012: 京都大学, 薬学研究科(研究院), 准教授 … More
2007 – 2011: Kyoto University, Graduate School of Pharmaceutical Sciences, Associate Professor
2009: 京都大学, 薬学研究科(研究院), 准教授
2004 – 2006: Kyoto University, Graduate School of Pharmaceutical Sciences, Department of Genomic Drug Discovery Sciences, Associate Professor, 薬学研究科, 助教授
2004: 京都大学, 大学院・薬学研究科ゲノム創薬科学分野, 助教授
2004: Kyoto Univ.Grad.Sch., Pharm.Sci., Genomic Drug Discovery Science, associated professor, 大学院・薬学研究科・ゲノム創薬科学分野, 助教授
2003: NATIONAL RESEARCH INSTITUTE FOR CHIOLD HEALTH AND DEVELOPMENT, ASSOCIATE DIRECTOR, 実験薬理研究室, 室長
2003: 国立成育医療センター研究所, 薬剤治療研究部, 室長
2002: 国立成育医療センター研究所, 薬剤治療研究部・実験薬理研究室, 室長
2001: 国立小児病院, (小児医療研究センター)・小児薬理研究部, 研究員
1997 – 2001: 国立小児病院, 小児医療研究センター・小児薬理研究部, 研究員
1998: 研究員
1995: 国立小児病院, 小児医療研究センター・小児薬理研究部, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy / Basic Section 47040:Pharmacology-related / Biological Sciences
Except Principal Investigator
応用薬理学・医療系薬学 / Biological pharmacy / Biological Sciences / Basic Section 56030:Urology-related / Applied health science / General physiology / General pharmacology / General pharmacology
Keywords
Principal Investigator
GPR120 / 脂肪酸受容体 / GLP-1 / フローサイトメトリー / オーファン受容体 / 肥満 / 蛍光プローブ / GPCR / ゲノム創薬科学 / 脂肪酸 … More / 細胞内局在 / GFP / gClqBP / Green Fluorescent Protein / yeast two-hybrid法 / α1Bアドレナリン受容体 / α1Aアドレナリン受容体 / アドレナリン受容体 / マルチオミクス / 発現プロファイル / 老化 / genome / pharmaceutical sciences / Microarray / signal transduction / Proteome / 質量分析 / ペプチド / 分泌 / ゲノム / 薬学 / マイクロアレイ / シグナル伝達 / プロテオーム / diabetes / obesity / enteroendocrine cells / ligand hunting / orphan receptor / データベース / 糖尿病 / 腸内分泌細胞 / リガンド探索 / ドッキングシミュレーション / シミュレーション / GPR40 / 分子生物学脂肪酸受容体 / フローサイトメーター / 薬理学 / 蛍光ブロープ / 分子生物学 / 3T3-L1 / 分化 / siRNA / 脂肪細胞 / 受容体ヘテロ二量体 / 細胞内pH / internalization / 蛍光標識リカンド / レーザー共焦点顕微鏡 / Green Fluorescent protein / ソーティング / リン酸化 / 共焦点レーザー顕微鏡 … More
Except Principal Investigator
DNAチップ / GPR120 / マイクロアレイ / 抗体 / DNA chip / 細胞内局在 / G蛋白質共役型受容体 / GPR40 / 不飽和脂肪酸受容体 / 食道がん / 三量体G蛋白共役型受容体 / 三量体Gタンパク質共役型受容体 / 多価不飽和脂肪酸 / 不飽和脂肪酸 / αリノレン酸 / 精子 / 長鎖不飽和脂肪酸受容体 / 長鎖不飽和脂肪酸 / 白色脂肪組織 / 肝臓 / NAFLD / NASH / fatty acid / DHA / GPR120/FFAR4 / 非アルコール性脂肪性肝炎(NASH) / GPR 40 family (GPR40,41,43) / GLP-1 (glucagon-like peptide 1) / Intracellular calcium / Free fatty acid / Enteroendocrine cell / Orphan G protein-coupled / GLP-1 / リガンド / 遊離脂肪酸受容体 / ノックアウトマウス / ERK / カルシウムシグナル / GPR40ファミリー(GPR40,41,43) / GLP-1(グルカゴン様ペプチド-1) / 細胞内カルシウム / 遊離脂肪酸 / 腸管内分泌細胞 / オーファンG蛋白共役型受容体 / Hydrion density / subcellular localization / Ca^<2+> oscillations / green fluorescent protein / α_1-adrenoceptor / α1受容体 / GFP / α_1受容体 / pH可視化測定 / micrarray / receptors / drugs / animal models / 受容体 / 薬物効果 / 疾患モデル動物 / library / subtractive / microarray / EDG5 / IgA nephropathy / cDNAチップ / ヒットピッキング法 / サブトラクト法 / 臓器別標準化ライブラリー / 標準化cDNAチップ / ブレオマイシン誘導性肺繊維症 / cDNAマイクロアレイ / 標準ライブラリー / ブレオマイシン誘導性肺線維症 / IgA腎症 / 標準化ライブラリー / intracellular localization / conforcal microscopy / visualized cell biology / molecular cloning / cellular signal transduction mechanism / alpha1-adrenoceptor subtypes / G-protein-coupled receptor / スプライスバリアント / 創薬ストラテジー / Green Fluorecent Protein / a1アドレナリン受容体 / サブタイプ受容体 / 共焦点顕微鏡 / 可視化技術 / クローニング / 細胞内情報伝達機構 / α1アドレナリン受容体サブタイプ / 細胞内カルシウム濃度 / 可視化解析 / GPR 40 / 三量体共役形受容体 / 細胞内シグナル伝達機構 / ミトコンドリア機能 / 水素イオン濃度 / 細胞内カルシウムイオン濃度測定 / 生命現象可視化 / Green Fluorescent Protein / バイオインフォマティックス / 疾患動物モデル / RNA / バイオインフォマッティックス / トランスクリプトーム / microRNA / 分化 / がん / 上皮細胞 / miRNA / バイオマーカー / 乳がん / 発現プロファイル / 超高感度DNAチップ / ネットワーク解析 / マイクロRNA / 包括的トランスクリプトーム解析 / ゲノム医療 / ゲノム情報 / バイオインフォマティクス / 食道癌 / 臨床検体 / 個別化医療 / ゲノム解析 / 網羅的 / 微量臨床検体 / テーラーメード医療 / 高感度チップ / 高感度化 Less
  • Research Projects

    (21 results)
  • Research Products

    (172 results)
  • Co-Researchers

    (27 People)
  •  Research on novel therapies and drugs through the elucidation of aging mechanismsPrincipal Investigator

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kyoto University
  •  Analysis of sperm function mediated by polyunsaturated fatty acid receptor GPR120

    • Principal Investigator
      Awaji Takeo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Saitama Medical University
  •  The mechanism of NASH development via long chain fatty acid receptor GPR120/FFAR4.

    • Principal Investigator
      OBATA TOKIO
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Kobe Gakuin University
  •  Elucidation of physiological role of the fatty acid receptor bycomputer simulation and the fluorescent probe detection systemPrincipal Investigator

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Physiological role of free fatty acid receptor GPR120.Principal Investigator

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  新規蛍光プローブを用いたG蛋白質共役型脂肪酸受容体ファミリー活性化機構の解析Principal Investigator

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  New genome medicine and drug discovery based on the comprehensive transcriptome analysis

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Long chain fatty acid receptor function using visualization of mitochondrial function

    • Principal Investigator
      AWAJI Takeo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Saitama Medical University
  •  微量臨床検体発現プロファイルによるがんの個別化治療

    • Principal Investigator
      辻本 豪三
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  脂肪酸受容体を介する脂肪細胞機能調節機構の解明Principal Investigator

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Regulation of peptides secretion by orphan G protein coupled receptorPrincipal Investigator

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  臨床ゲノム研究のための高感度ゲノム機能解析システムの開発

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Identification of ligand and function of novel group of free fatty acid receptors by using genome information.

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  A novel functional genomics approach and ligand hunting for orphan seven transmembrane receptors.Principal Investigator

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
      National Research Institute for Child Health and Development
  •  Relationship between subcellular localization of α-adrenoceptor subtypes and function on ischemia

    • Principal Investigator
      AWAJI Takeo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Tokyo Women's Medical University
  •  In vitro analysis of signaling pathway involved in pathgenesis of renal or cardiac disease using animal models.

    • Principal Investigator
      TANOUE Akito
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      NATIONAL RESEARCH INSTITUTE FOR CHIOLD HEALTH AND DEVELOPMENT
  •  7回膜貫通型受容体の蛋白間相互作用の解析とその生理的意義Principal Investigator

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Research Institute for Child Health and Development
  •  Analysis of disease-related genes by using microaaray DNA chip with the normalized cDNA library

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      NATIONAL CHILDREN'S MEDICAL RESEARCH CENTER
  •  G蛋白共役型受容体の細胞内局在の分子機構の解析Principal Investigator

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Research Institute for Child Health and Development
  •  Use of G-protein-coupled receptor subtype genes for novel drug discovery

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      NATIONAL CHILDREN'S MEDICAL RESEARCH CENTER
  •  G蛋白質共役受容体の細胞内動態の解析Principal Investigator

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      National Research Institute for Child Health and Development

All 2021 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation Patent

  • [Journal Article] A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus2021

    • Author(s)
      Iwasa Kensuke、Yamamoto Shinji、Yamashina Kota、Yagishita-kyo Nan、Maruyama Kei、Awaji Takeo、Takei Yoshinori、Hirasawa Akira、Yoshikawa Keisuke
    • Journal Title

      Journal of Neuroinflammation

      Volume: 18 Issue: 1 Pages: 304-304

    • DOI

      10.1186/s12974-021-02361-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09148, KAKENHI-PROJECT-18K06899, KAKENHI-PROJECT-21K06807, KAKENHI-PROJECT-18K17933
  • [Journal Article] A Future Perspective on the Involvement of <i>n</i>-3 Polyunsaturated Fatty Acid in the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis2016

    • Author(s)
      Nakamoto K, Obata T, Hirasawa A, Ih Kim K, Ryang Kim S, Tokuyama S
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 136 Issue: 4 Pages: 583-589

    • DOI

      10.1248/yakushi.15-00264-4

    • NAID

      130005140766

    • ISSN
      0031-6903, 1347-5231
    • Year and Date
      2016-04-01
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12715
  • [Journal Article] FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models2013

    • Author(s)
      Takeuchi M, Hirasawa A, Hara T, Kimura I, Hirano T, Suzuki T, Miyata N, Awaji T, Ishiguro M, Tsujimoto G
    • Journal Title

      Br J Pharmacol

      Volume: 168 Pages: 1570-1583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors2013

    • Author(s)
      Hou Z, Oishi S, Suzuki Y, Kure T, Nakanishi I, Hirasawa A, Tsujimoto G, Ohno H, Fujii N
    • Journal Title

      Org Biomol Chem

      Volume: 11 Pages: 3288-3296

    • NAID

      120005474525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Physiological functions of fatty acid receptors and their therapeutic potential2012

    • Author(s)
      Hara T, Hirasawa A, Ichimura A, Kimura I, Tsujimoto G.
    • Journal Title

      Nihon Yakurigaku Zasshi

      Volume: 140 Pages: 275-279

    • NAID

      10031130803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles.2012

    • Author(s)
      Suzuki Y, Oishi S, Takei Y, Yasue M, Misu R, Naoe S, Hou Z, Kure T, Nakanishi I, Ohno H, Hirasawa A, Tsujimoto G, Fujii N
    • Journal Title

      Org Biomol Chem

      Volume: 10 Pages: 4907-4915

    • NAID

      120005244966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Paradoxical Downregulation of CXC Chemokine Receptor 4 Induced by Polyphemusin II-derived Antagonists.2012

    • Author(s)
      Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Navenot J M, Peiper S C, Fujii N
    • Journal Title

      Bioconjug Chem

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human2012

    • Author(s)
      Ichimura A
    • Journal Title

      Nature

      Volume: 483 Issue: 7389 Pages: 350-354

    • DOI

      10.1038/nature10798

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117008, KAKENHI-PROJECT-21390021, KAKENHI-PROJECT-23659038, KAKENHI-PROJECT-23890019, KAKENHI-PROJECT-24590327
  • [Journal Article] Development and application of fluorescent SDF-1 derivatives2012

    • Author(s)
      Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N
    • Journal Title

      Future Med Chem.

      Volume: 4 Pages: 837-844

    • NAID

      120005285488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation2012

    • Author(s)
      Inoue D, Kimura I, Wakabayashi M, Tsumoto H, Ozawa K, Hara T, Takei Y, Hirasawa A, Ishihama Y, Tsujimoto G
    • Journal Title

      FEBS Lett

      Volume: 586 Pages: 1547-1554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Structure-Based Design of Novel Potent Protein Kinase CK2 (CK2) Inhibitors with Phenyl-azole Scaffolds2012

    • Author(s)
      Hou Z, Nakanishi I, Kinoshita T, Takei Y, Yasue M, Misu R, Suzuki Y, Nakamura S, Kure T, Ohno H, Murata K, Kitaura K, Hirasawa A, Tsujimoto G, Oishi S, Fujii N
    • Journal Title

      J Med Chem

      Volume: 55 Pages: 2899-2903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Journal Article] Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor2011

    • Author(s)
      Kimura I, Inoue D, Hirasawa A, et al
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 108(19) Issue: 19 Pages: 8030-8035

    • DOI

      10.1073/pnas.1016088108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021, KAKENHI-PROJECT-22790065
  • [Journal Article] Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders2011

    • Author(s)
      Hara T, Hirasawa A, et al
    • Journal Title

      J Pharm Sci

      Volume: 100(9) Issue: 9 Pages: 3594-3601

    • DOI

      10.1002/jps.22639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021, KAKENHI-PROJECT-23890019
  • [Journal Article] New Frontiers in Gut Nutrient Sensor Research: Free Fatty Acid Sensing in the Gastrointestinal Tract2010

    • Author(s)
      Miyauchi S, Hirasawa A, et al
    • Journal Title

      J Pharmacol Sci

      Volume: 112 Issue: 1 Pages: 19-24

    • DOI

      10.1254/jphs.09R09FM

    • NAID

      10027908410

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] 脂肪酸受容体に対するリガンド探索,生理機能の解明と創薬応用2010

    • Author(s)
      平澤明、辻本豪三
    • Journal Title

      医学のあゆみ

      Volume: vol.233, no.9 Pages: 755-760

    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] New frontiers in gut nutrient sensor research : free fatty acid sensing in the gastrointestinal tract.2010

    • Author(s)
      Miyauchi S, Hirasawa A, Ichimura A, Hara T, Tsujimoto G.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 112 Pages: 19-24

    • NAID

      10027908410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Structure-activity relationships of GPR120 agonists based on a docking simulation.2010

    • Author(s)
      Sun Q, Hirasawa A, Hara T, Kimura I, Adachi T, Awaji T, Ishiguro M, Suzuki T, Miyata N, Tsujimoto G.
    • Journal Title

      Molecular Pharmacology

      Volume: 78 Pages: 804-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Free fatty acid sensing in the gastrointestinal tract2010

    • Author(s)
      Miyauchi S, Hirasawa A, 他
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 112(1) Pages: 19-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] Neuferricin, a novel extracellular heme-binding protein, promotes neurogenesis.2010

    • Author(s)
      Kimura I, Nakayama Y, Konishi M, Kobayashi T, Mori M, Ito M, Hirasawa A, Tsujimoto G, Ohta M, Itoh N, Fujimoto M.
    • Journal Title

      Journal of Neurochemistry

      Volume: 112 Pages: 1156-1167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Structure-Activity Relationships of GPR120 Agonists Based on a Docking Simulation2010

    • Author(s)
      Sun Q, Hirasawa A, et al
    • Journal Title

      Mol Pharmacol

      Volume: 78(5) Issue: 5 Pages: 804-810

    • DOI

      10.1124/mol.110.066324

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] Inhibition of heat shock protein 90 attenuates adenylate cyclase sensitization after chronic morphine treatment.2010

    • Author(s)
      Koshimizu TA, Tsuchiya H, Tsuda H, Fujiwara Y, Shibata K, Hirasawa A, Tsujimoto G, Fujimura A.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 392 Pages: 603-607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Structure-Activity Relationships of GPR120 Agonists Based on a Docking Simulation.2010

    • Author(s)
      Sun Q, Hirasawa A, Hara T, 他
    • Journal Title

      Mol Pharmacol

      Volume: 78 Pages: 804-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] Flow cytometry-based binding assay for GPR40 (FFAR1 ; free fatty acid receptor 1).2009

    • Author(s)
      Hara T, Hirasawa A, Sun Q, Koshimizu T A, Itsubo C, Sadakane K, Awaji T, Tsujimoto G.
    • Journal Title

      Mol Pharmacol. 75(1)

      Pages: 85-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Distribution and regulation of protein expression of the free fatty acid receptor GPR120.2009

    • Author(s)
      Miyauchi S, Hirasawa A, Iga T, Liu N, Itsubo C, Sadakane K, Hara T, Tsuj imoto G
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 379 (4)

      Pages: 427-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis2009

    • Author(s)
      Ichimura A, Hirasawa A, et al
    • Journal Title

      Prostaglandins & Other Lipid Mediators

      Volume: 89 Issue: 3-4 Pages: 82-88

    • DOI

      10.1016/j.prostaglandins.2009.05.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] Flow cytometry-based binding assay for GPR40(FFAR1; free fatty acid receptor 1).2009

    • Author(s)
      Hara T, Hirasawa A, Sun Q, Koshimizu TA, Itsubo C, Sadakane K, Awaji T, Tsujimoto G.
    • Journal Title

      Molecular Pharmacology 75(1)

      Pages: 85-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590260
  • [Journal Article] Novel selective ligands for free fatty acid receptors GPR120 and GPR402009

    • Author(s)
      Hara T, Hirasawa A, et al
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol

      Volume: 380(3) Issue: 3 Pages: 247-255

    • DOI

      10.1007/s00210-009-0425-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Journal Article] Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists2008

    • Author(s)
      Suzuki T, Igari S I, Hirasawa A, Hata M, Ishiguro M, Fujieda H, Itoh Y, Hirano T, Nakagawa H, Ogura M
    • Journal Title

      J Med Chem. 51(23)

      Pages: 7640-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Free fatty acid receptors and drug discovery.2008

    • Author(s)
      Hirasawa A, Hara T, Katsuma S, Adachi T, Tsujimoto G.
    • Journal Title

      Biol Pharm Bull 31

      Pages: 1847-1851

    • NAID

      40017107059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Structure-activity relationships of pyrazine-based CK2 inhibitors : synthesis and evaluation of 2, 6-disubstituted pyrazines and 4, 6-disubstituted pyrimidines.2008

    • Author(s)
      Suzuki Y, Cluzeau J, Hara T, Hirasawa A, Tsujimoto G, Oishi S, Ohno H, Fujii N.
    • Journal Title

      Arch Pharm (Weinheim) 341

      Pages: 554-561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Cloning and characterization of the rat free fatty acid receptor GPR120 : in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.2008

    • Author(s)
      Tanaka T, Yano T, Adachi T, Koshimizu T A, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377(46)

      Pages: 515-522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Synthesis and application of fluorescein-and biotin-labeled molecular probes for the chemokine receptor CXCR4.2008

    • Author(s)
      Oishi S, Masuda R, Evans B, Ueda S, Goto Y, Ohno H, Hirasawa A, Tsujimoto G, Wang Z, Peiper S C, Naito T, Kodaraa E, Matsuoka M, Fujii N.
    • Journal Title

      Chembiochem. 9(7)

      Pages: 1154-1158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40 (FFAR1 ; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A, Itsubo C, Sadakane K, Hara T, Shinagawa S, Koga H, Nose H, Koshimizu T A, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 365(1)

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40 (FFAR1; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A, Itsubo C, Sadakane K, Hara T, Shinagawa S, Koga H, Nose H, Koshimizu TA, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 365

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40 (FFARl ; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A, Itsubo C, Sadakane K, Hara T, Shinagawa S, Koga H, Nose H, Koshimizu TA, Tsujimoto G.
    • Journal Title

      Biochei Biophys Res Commun. 365

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Synthesis and application of fluorescein-and biotin-labeled molecular probes for the chenmokine receptor CXCR4.2008

    • Author(s)
      Oishi S, Masuda R, Evans B, Ueda S, Goto Y, Ohno H, Hirasawa A, Tsujimoto G, Wang Z, Peiper SC, Naito T, Kodama E, Matsuoka M, Fujii N.
    • Journal Title

      Chembiochem. 9

      Pages: 1154-1158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] In silico approach to identify the expression of the undiscovered molecules from microarray public database : identification of odorant receptors expressed in non-olfactory tissues.2008

    • Author(s)
      Ichimura A, Kadowaki T, Narukawa K, Togiya K, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377(2)

      Pages: 159-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Administration of perilla oil coated with Calshell increases glucagon-like peptide secretion.2008

    • Author(s)
      Adachi T, Yanaka H, Kanai H, Nozaki M, Takahara Y, Tsuda M, Jonouchi T, Tsuda K, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biol Pharm Bull 31

      Pages: 1021-1023

    • NAID

      110006663973

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] In silico approach to identify the expression of the undiscovered molecules from microarray public database : identification of odorant receptors expressed in non-olfactory tissues.2008

    • Author(s)
      Ichiinura A, Kadowaki T, Narukawa K, Togiya K, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377

      Pages: 159-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] In silico approach to identify the expression of the undiscovered molecules from microarray public database: identification of odorant receptors expressed in non-olfactory tissues.2008

    • Author(s)
      Ichimura A, Kadowaki T, Narukawa K, Togiya K, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377(2)

      Pages: 159-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40 (FFAR1; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A, Itsubo C, Sadakane K, Hara T, Shinagawa S, Koga H, Nose H, Koshimizu TA, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 365

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] In silico approach to identify the expression of the undiscovered molecules from microarray public database: identification of odorant receptors expressed in non-olfactory tissues.2008

    • Author(s)
      Ichimura A, Kadowaki T, Narukawa K, Togiya K, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377(2)

      Pages: 159-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40(FFAR1; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A.
    • Journal Title

      Biochem Biophys Res Commun. 365

      Pages: 22-28

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40(FFAR1 ; free fatty acid receptor 1)2008

    • Author(s)
      Hirasawa, A
    • Journal Title

      Biochem Biophys Res Commun (refereed) 365

      Pages: 22-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Free fatty acids induce cholecystokinin secretion through GPR120.2008

    • Author(s)
      Tanaka T, Katsuma S, Adachi T, Koshimizu T A, Hirasawa A, Tsujiraoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377(46)

      Pages: 523-527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Journal Article] Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists.2008

    • Author(s)
      Suzuki T, Igari SI, Hirasawa A, Hata M, Ishiguro M, Fujieda H, Itoh Y, Hirano T, Nakagawa H, Ogura M, Makishima M, Tsujimoto G, Miyata N.
    • Journal Title

      J Med Chem 51

      Pages: 7640-7644

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Immunological tolerance-related genes in a spontaneous tolerant model of rat liver transplantation explored by suppression subtractive hybridization.2008

    • Author(s)
      Zhang H, Ohmi K, Hirasawa A, Enosawa S, Hara Y, Tamura A, Tsuiimoto G.
    • Journal Title

      Cell Transplant. 17

      Pages: 195-201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Cloning and characterization of the rat free fatty acid receptor GPR120 : in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.2008

    • Author(s)
      Tanaka T, Yano T, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377

      Pages: 515-522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Free fatty acids induce cholecystokinin secretion through GPR120.2008

    • Author(s)
      Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schiiedebergs Arch Pharmacol. 377

      Pages: 523-527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Glucocorticoid-induced alternative promoter usage for a novel 5' variant of granzyme A.2007

    • Author(s)
      Ruike Y, Katsuma S, Hirasawa A, Tsujimoto G.
    • Journal Title

      J Hum Genet. 52(2)

      Pages: 172-178

    • NAID

      10018514614

    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] The regulation of adipogenesis through GPR1202007

    • Author(s)
      Gotoh C, Hong YH, Iga T, Hishikawa D, Suzuki Y, Song SH, Choi KC, Adachi T, Hirasawa A, Tsujimoto G, Sasaki S, Roh SG.
    • Journal Title

      Biocheni. Biophys. Res. Commun. 354

      Pages: 591-597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Free fatty acids induce cholecystokinin secretion through GPR120.2007

    • Author(s)
      Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Free fatty acids induce cholecystokinin secretion through GPR120.2007

    • Author(s)
      Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] The regulation of adipogenesis through GPR1202007

    • Author(s)
      Gotoh C, Hong YH, Iga T, Hishikawa D, Suzuki Y, Song SH, Choi KC, Adachi T, Hirasawa A, Tsujimoto G, Sasaki S, Roh SG.
    • Journal Title

      Biochem Biophys Res Commun. 354(2)

      Pages: 591-597

    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Glucocorticoid-induced alternative promoter usage for a novel 5' variant of granzyme A.2007

    • Author(s)
      Ruike Y, Katsuma S, Hirasawa A, Tsujimoto G.
    • Journal Title

      J. Hum. Genet. 52

      Pages: 172-178

    • NAID

      10018514614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18018024
  • [Journal Article] Glucocorticoid-induced alternative promoter usage for a novel 5' variant of granzyme A.2007

    • Author(s)
      Ruike Y, Katsuma S, Hirasawa A, Tsujimoto G
    • Journal Title

      J Hum Genet. 52(2)

      Pages: 172-178

    • NAID

      10018514614

    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] The regulation of adipogenesis through GPR1202007

    • Author(s)
      Gotoh C, Hong YH, Iga T, Hishikawa D, Suzuki Y, Song SH, Choi KC, Adachi T, Hirasawa A, Tsujimoto G, Sasaki S, Roh SG
    • Journal Title

      Biochem Biophys Res Commun. 354(2)

      Pages: 591-597

    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Glucocorticoid-induced alternative promoter usage for a novel 5' variant granzyme A.2007

    • Author(s)
      Ruike Y, Katsuma S, Hirasawa A, Tsujimoto G.
    • Journal Title

      J. Hum. Genet. 52

      Pages: 172-178

    • NAID

      10018514614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 340

      Pages: 332-337

    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu TA, Hirasawa A, Tsujimoto G
    • Journal Title

      Biochem Biophys Res Commun. 340

      Pages: 332-337

    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Developmental aberrations of liver gene expression in bovine fetuses derived from somatic cell nuclear transplantation.2006

    • Author(s)
      Herath CB., Ishiwata H., Shiojima S., Kadowaki T., Katstma S., Ushizowa K., Imai K., Takahashi T., Hirasawa A., Takahashi S., Izaike Y., Tsujimoto G., Hashizume K.
    • Journal Title

      Cloning Stem Cells. 8(2)

      Pages: 79-95

    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Developmental aberrations of liver gene expression in bovine fetuses derived from somatic cell nuclear transplantation.2006

    • Author(s)
      Herath CB, Ishiwata H, Shiojima S, Kadowaki T, Katsuma S, Ushizawa K, Imai K, Takahashi T, Hirasawa A, Takahashi S, Izaike Y, Tsujimoto G, Hashizume K..
    • Journal Title

      Cloning Stem Cells. 8(2)

      Pages: 79-95

    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Free fatty acids administered into the colon promotes the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu T, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem. Biophys. Res. Commun. 340

      Pages: 332-337

    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Monitoring ligand-mediated internalization of G protein-coupled receptor as a novel pharmacological approach.2006

    • Author(s)
      Fukunaga S, Setoguchi S, Hirasawa A, Tsujimoto G.
    • Journal Title

      Life Sci. 80(1)

      Pages: 17-23

    • Data Source
      KAKENHI-PROJECT-18390024
  • [Journal Article] Monitoring ligand-mediated internalization of G protein-coupled receptor as a novel pharmacological approach.2006

    • Author(s)
      Fukunaga S, Setoguchi S, Hirasawa A, Tsujimoto G
    • Journal Title

      Life Sci. 80(1)

      Pages: 17-23

    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Free fatty acids administered into the colon promotes the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu T, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem. Biophys. Res. Commun. Vol.340

      Pages: 332-337

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids administered into the colon promotes the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu T, Hirasawa A, Tsujimoto G
    • Journal Title

      Biochem. Biophys. Res. Commun. 340

      Pages: 332-337

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.2005

    • Author(s)
      Yamada M, Katsuma S, Adachi T, Hirasawa A, Shiojima S, Kadowaki T, Okuno Y, Koshimizu TA, Fujii S, Sekiya Y, Miyamoto Y, Tamura M, Yumura W, Nihei H, Kobayashi M, Tsujimoto G.
    • Journal Title

      Proc. Natl. Acad. Sci. U S A. Vol.102

      Pages: 7736-7741

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids regulate gut incretin glucagons-like peptide_I secretion through GPR120.2005

    • Author(s)
      Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G
    • Journal Title

      Nat. Med. Vol.11

      Pages: 90-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G
    • Journal Title

      J. Biol. Chem. Vol.280

      Pages: 19507-19515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.2005

    • Author(s)
      Yamada M, Katsuma S, Adachi T, Hirasawa A, Shiojima S, Kadowaki T, Okuno Y, Koshimizu TA, Fujii S, Sekiya Y, Miyamoto Y, Tamura M, Yumura W, Nihei H, Kobayashi M, Tsujimoto G
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 102

      Pages: 7736-7741

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids regulates gut incretin glucagons-like peptide-1 secretion through GPR120.2005

    • Author(s)
      Hirasawa A
    • Journal Title

      Nat.Med. 11

      Pages: 90-94

    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 329

      Pages: 386-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Related Articles, Links Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G.
    • Journal Title

      J Biol Chem. 280(20)

      Pages: 19507-19515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hirasawa A, Tsujimoto G
    • Journal Title

      Biochem. Biophys. Res. Commun. Vol.329

      Pages: 386-390

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids regulate gut incretin glucagons-like peptide-1 secretion through GPR120.2005

    • Author(s)
      Hirasawa A
    • Journal Title

      Nat.Med. 11

      Pages: 90-94

    • Data Source
      KAKENHI-PROJECT-17019038
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.2005

    • Author(s)
      Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G.
    • Journal Title

      Nature Medicine. 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR1202005

    • Author(s)
      Hirasawa, A., Awaji, T.et al.
    • Journal Title

      Nat Med 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590192
  • [Journal Article] Free fatty acids regulate gut incretin glucagons-like peptide_1 secretion through GPR120.2005

    • Author(s)
      Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G
    • Journal Title

      Nat. Med. 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hirasawa A, Tsujimoto G
    • Journal Title

      Biochem. Biophys. Res. Commun. 329

      Pages: 386-390

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR 120.2005

    • Author(s)
      Hirasawa, A., K.Tsumaya, T.Awaji, S.Katsuma, T.Adachi, M.Yamada, Y.Sugimoto, S.Miyazaki, G.Tsujimoto
    • Journal Title

      Nat Med. 11

      Pages: 90-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590192
  • [Journal Article] Transcriptional regulation of connective tissue growth factor by sphingosine 1-phosphate in rat cultured mesangial cells.2005

    • Author(s)
      Katsuma S, Ruike Y, Yano T, Kimura M, Hirasawa A, Tsujimoto G
    • Journal Title

      FEBS Lett. 579

      Pages: 2576-2582

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G
    • Journal Title

      J. Biol. Chem. 280

      Pages: 19507-19515

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Transcriptional regulation of connective tissue growth factor by sphingosine 1-phosphate in rat cultured mesangial cells.2005

    • Author(s)
      Katsuma S, Ruike Y, Yano T, Kimura M, Hirasawa A, Tsujimoto G
    • Journal Title

      FEBS Lett. Vol.579

      Pages: 2576-2582

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A et al.
    • Journal Title

      J Biol Chem in press

    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.2005

    • Author(s)
      Hirasawa A et al.
    • Journal Title

      Nature Medicine 11(1)

      Pages: 90-94

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 329(1)

      Pages: 386-390

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.2005

    • Author(s)
      Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A et al.
    • Journal Title

      J Biol Chem 280(20)

      Pages: 19507-19515

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] cDNA microarray analysis of bovine embryo gene expression profiles during the pre-implantation period.2004

    • Author(s)
      Ushizawa K, Herath CB, Kaneyama K, Shiojima S, Hirasawa A et al.
    • Journal Title

      Reprod Biol Endocrinol. 2(1)

      Pages: 77-77

    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Carvedilol selectively inhibits oscillatory intracellular calcium changes evoked by human alpha1D- and alpha1B-adrenergic receptors.2004

    • Author(s)
      Koshimizu TA, Tsujimoto G, Hirasawa A, Kitagawa Y, Tanoue A.
    • Journal Title

      Cardiovasc Res. 63(4)

      Pages: 662-672

    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Pregnancy-associated changes in genome-wide gene expression profiles in the liver of cow throughout pregnancy.2004

    • Author(s)
      Herath CB, Shiojima S, Ishiwata H, Katsuma S, Kadowaki T, Ushizawa K, Imai K, Takahashi T, Hirasawa A, Tsujimoto G, Hashizume K.
    • Journal Title

      Biochem Biophys Res Commun 313

      Pages: 666-680

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] cDNA microarray analysis of bovine embryo gene expression profiles during the pre-implantation period.2004

    • Author(s)
      Ushizawa K, Herath CB, Kaneyama K, Shiojima S, Hirasawa A, et al.
    • Journal Title

      Reprod Biol Endocrinol 2

      Pages: 77-92

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Gene expression profile in experimental mesangial proliferative glomerulonephritis.2004

    • Author(s)
      Izumi Y, Izumiya Y, Shiota M, Yukimura T, Shiojima S, Yamada M, Kadowaki T, Katsuma S, Hirasawa A et al.
    • Journal Title

      J Pharmacol Sci. 96(1)

      Pages: 91-94

    • NAID

      10014166433

    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Pregnancy-associated changes in genome-wide gene expression profiles in the liver of cow throughout pregnancy.2004

    • Author(s)
      Herath CB, Shiojima S, Ishiwata H, Katsuma S, Kadowaki T, Ushizawa K, Imai K, Takahashi T, Hirasawa A, Tsujimoto G, Hashizume K.
    • Journal Title

      Biochem Biophys Res Commun. 313

      Pages: 666-680

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] cDNA microarray analysis of bovine embryo gene expression profiles during the pre-implantation period.2004

    • Author(s)
      Ushizawa K, Herath CB, Kaneyama K, Shiojima S, Hirasawa A, Takahashi T, Imai K, Ochiai K, Tokunaga T, Tsunoda Y, Tsujimoto G, Hashizume K.
    • Journal Title

      Reprod Biol Endocrinol. 2

      Pages: 77-92

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Recent advance of α1-adrenoceptors pharmacology.2003

    • Author(s)
      Koshimizu T, Tanoue A, Hirasawa A, Yamauchi J, Tsujimoto G
    • Journal Title

      Pharmacology & Therapeutics 98

      Pages: 235-244

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Transcriptional profiling of gene expression patterns during sphingosine 1-phosphate-induced mesangial cell proliferation.2003

    • Author(s)
      Katsuma S, Hirasawa A, Tanoue A, Yano J, Tsujimoto G, et al.
    • Journal Title

      Biochem Biophys Res Commun. 300

      Pages: 577-584

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Recent advance of α1-adrenoceptors pharmacology.2003

    • Author(s)
      Koshimizu T, Tanoue A, Hirasawa A, Yamauchi J, Tsujimoto G.
    • Journal Title

      Pharmacology & Therapeutics 98

      Pages: 235-244

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Granzyme A mediates glucocorticoid-induced apoptosis in leukemia cells.2003

    • Author(s)
      Yamada M, Hirasawa A, Shiojima S, Tsujimoto G.
    • Journal Title

      FASEB J. 17

      Pages: 1712-1714

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Determination of a novel haplotype of beta 2 adrenergic receptor in the Japanese population by the combination of the electronic microchip assay using the nanoChip system with allelespecific PCR.2003

    • Author(s)
      Yoshida N, Sugiyama M, Tanoue A, Hirasawa A, Tsuijimoto G.
    • Journal Title

      Drug Metabolism and Pharmacokinetics 17

      Pages: 532-539

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Transcriptional profiling of gene expression patterns during sphingosine 1-phosphate-induced mesangial cell proliferation.2003

    • Author(s)
      Katsuma S, Hada Y, Shiojima S, Hirasawa A, Tanoue A, Takagaki K, Ohgi T, Yano J, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 300

      Pages: 577-584

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Alpha 1-adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1.2003

    • Author(s)
      Shibata K, Katsuma S, Koshimizu T, Shinoura H, Hirasawa A, Tanoue A, Tsujimoto G.
    • Journal Title

      J Biol Chem. 278

      Pages: 672-678

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Determination of a novel haplotype of beta 2 adrenergic receptor in the Japanese population by the combination of the electronic microchip assay using the nanoChip system with allelespecific PCR.2003

    • Author(s)
      Yoshida N, Sugiyama M, Tanoue A, Hirasawa A, Tsuijimoto G
    • Journal Title

      Drug Metabolism and Pharmacokinetics 17

      Pages: 532-539

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Alpha 1-adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1.2003

    • Author(s)
      Shibata K, Katsuma S, Hirasawa A, Tanoue A, Tsujimoto G, et al.
    • Journal Title

      J Biol Chem. 278

      Pages: 672-678

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Granzyme A mediates glucocorticoid-induced apoptosis in leukemia cells.2003

    • Author(s)
      Yamada M, Hirasawa A, Shiojima S, Tsujimoto G.
    • Journal Title

      FASEB J 17

      Pages: 1712-1714

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590095
  • [Journal Article] Signalling mechanisms in sphingosine 1-phosphate-promoted mesangial cell proliferation.2002

    • Author(s)
      Katsuma S, Shiojima S, Hirasawa A, Tanoue A, Takagaki K, Tsujimoto G, et al.
    • Journal Title

      Genes Cells. 7

      Pages: 1217-1230

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] SNP genotyping in the beta2-adrenergic receptor by electronic microchip assay, DHPLC and direct sequencing.2002

    • Author(s)
      Yoshida N, Nishimaki Y, Tanoue A, Hirasawa A, Tsujimoto G, et al.
    • Journal Title

      J.Hum.Genet. 47

      Pages: 500-503

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Signalling mechanisms in sphingosine 1-phosphate-promoted mesangial cell proliferation.2002

    • Author(s)
      Katsuma S, Hada Y, Ueda T, Shiojima S, Hirasawa A, Tanoue A, Takagaki K, Ohgi T, Yano J, Tsujimoto G.
    • Journal Title

      Genes Cells. 7

      Pages: 1217-1230

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Recent progress in alpha 1-adrenoceptor pharmacology.2002

    • Author(s)
      Koshimizu T, Yamauchi J, Hirasawa A, Tanoue A, Tsujimoto G.
    • Journal Title

      J.Biol.Pharma.Bull. 25

      Pages: 401-408

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Recent progress in alpha 1-adrenoceptor pharmacology.2002

    • Author(s)
      Koshimizu T, Yamauchi J, Hirasawa A, Tanoue A, Tsujimoto G
    • Journal Title

      Biol.Pharma.Bull. 25

      Pages: 401-408

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Journal Article] Key amino acids for differential coupling of alpha1-adrenergic receptor subtypes to Gs.2002

    • Author(s)
      Shinoura H, Shibata K, Hirasawa A, Tanoue A, Hashimoto K, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 299

      Pages: 142-147

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14572173
  • [Patent] G蛋白質共役型レセプター作動剤2011

    • Inventor(s)
      辻本豪三、平澤明, 他
    • Industrial Property Rights Holder
      京都大学
    • Industrial Property Number
      2011-016446
    • Filing Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Patent] Gタンパク質共役型レセプター作動剤2007

    • Inventor(s)
      辻本豪三、平澤明、宮田直樹、鈴木孝禎、高原義之、石黒正路、畑美絵
    • Industrial Property Rights Holder
      辻本豪三、平澤明、宮田直樹、鈴木孝禎、高原義之、石黒正路、畑美絵
    • Industrial Property Number
      2007-116372
    • Filing Date
      2007-04-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Patent] Gタンパク質共役型レセプターの作動剤および医薬2007

    • Inventor(s)
      辻本豪三、平澤明
    • Industrial Property Rights Holder
      辻本豪三、平澤明
    • Industrial Property Number
      2007-138654
    • Filing Date
      2007-05-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Patent] Gタンパク質共役型レセプター作動剤2007

    • Inventor(s)
      辻本豪三、平澤明、宮田直樹、鈴木孝禎、高原義之、石黒正路、畑美絵
    • Industrial Property Rights Holder
      辻本豪三、平澤明、宮田直樹、鈴木孝禎、高原義之、石黒正路、畑美絵
    • Industrial Property Number
      2007-116372
    • Filing Date
      2007-04-26
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Patent] Gタンパク質共役型レセプターの作動剤および医薬2007

    • Inventor(s)
      辻本豪三、平澤明
    • Industrial Property Rights Holder
      辻本豪三、平澤明
    • Industrial Property Number
      2007-138654
    • Filing Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Patent] 腸炎又は神経障害の治療又は予防に供される医薬組成物2006

    • Inventor(s)
      平澤明, 辻本豪三
    • Industrial Property Rights Holder
      ファルマフロンティア株式会社, 平澤明, 辻本豪三
    • Filing Date
      2006-01-18
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Patent] 腸炎又は神経障害の治療又は予防に供される医薬組成物2006

    • Inventor(s)
      平澤 明, 辻本 豪三
    • Industrial Property Rights Holder
      ファルマフロンティア株式会社, 平澤 明, 辻本 豪三
    • Filing Date
      2006-01-18
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Patent] 腸炎又は神経障害の治療又は予防に供される医薬組成物2006

    • Inventor(s)
      平澤 明, 辻本 豪三
    • Industrial Property Rights Holder
      ファルマフロンティア株式会社, 平澤 明, 辻本 豪三
    • Filing Date
      2006-01-18
    • Data Source
      KAKENHI-PROJECT-17019038
  • [Patent] 腎ガン患者予後予測用組成物および方法2005

    • Inventor(s)
      妙本 陽, 秋山 英雄, 小園 聡子, 野村 修, 信正 均, 辻本 豪三, 小川 修, 平澤 明, 中村 英二郎
    • Industrial Property Rights Holder
      東レ株式会社, 国立大学法人京都大学
    • Industrial Property Number
      2005-255499
    • Filing Date
      2005-09-02
    • Data Source
      KAKENHI-PROJECT-17019038
  • [Patent] 腎ガン患者予後予測用組成物および方法2005

    • Inventor(s)
      妙本陽, 秋山英雄, 小園聡子, 野村修, 信正均, 辻本豪三, 小川修, 平澤明, 中村英二郎
    • Industrial Property Rights Holder
      東レ株式会社, 国立大学法人京都大学
    • Industrial Property Number
      2005-255499
    • Filing Date
      2005-09-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Patent] 腎ガン患者予後予測用組成物および方法2005

    • Inventor(s)
      妙本 陽, 秋山 英雄, 小園 聡子, 野村 修, 信正 均, 辻本 豪三, 小川 修, 平澤 明, 中村 英二郎
    • Industrial Property Rights Holder
      東レ株式会社, 国立大学法人京都大学
    • Industrial Property Number
      2005-255499
    • Filing Date
      2005-09-02
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Presentation] GPR120/FFAR4 アゴニストは白色脂肪細胞による炎症を抑制し、非アルコール性脂肪性肝炎を阻止する2016

    • Author(s)
      中本 賀寿夫, 島田 幸季, 原田 慎一, 森本 泰子, 平澤 明, 徳山 尚吾
    • Organizer
      第 130 回日本薬理学会 近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15K12715
  • [Presentation] NASH の病態進行における長鎖脂肪酸受容体 GPR120/FFAR4 の関与2016

    • Author(s)
      宮城景, 中本賀寿夫, 小畑友紀雄, 原田慎一, 森本泰子, 平澤明, 金啓二, 金守良, 徳山尚吾
    • Organizer
      日本薬学会 136 年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15K12715
  • [Presentation] NASH 進行過程における長鎖脂肪酸受容体 GPR120/FFA4 シグナルの関与2015

    • Author(s)
      宮城景, 中本賀寿夫, 原田慎一, 小畑友紀雄, 森本泰子, 金啓二, 金守良, 平澤明, 徳山尚吾
    • Organizer
      第 127 回 日本薬理学会 近畿部会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-06-24
    • Data Source
      KAKENHI-PROJECT-15K12715
  • [Presentation] 脂肪酸センサーGPR120 は食事性肥満の原因遺伝子である2012

    • Author(s)
      平澤明
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡県福岡国際会議場・マリンメッセ福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] 薬物スクリーニングへのイメージング技術の応用2012

    • Author(s)
      平澤明、辻本豪三、原貴史 シンポジウム
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学キャンパス内(北海道)
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] 薬物スクリーニングへのイメージング技術の応用2012

    • Author(s)
      平澤明、辻本豪三、原貴史
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学キャンパス内(北海道)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] 脂肪酸受容体GPR120の構造活性相関と薬理学的機能解析2012

    • Author(s)
      原貴史、平澤明、竹内理人、鮎川久美子、白井遼平、辻本豪三
    • Organizer
      第41回日本心脈管作動物質学会
    • Place of Presentation
      秋田キャッスルホテル(秋田県)
    • Year and Date
      2012-02-10
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] 薬物スクリーニングへのイメージング技術の応用2012

    • Author(s)
      平澤明、辻本豪三、原貴史
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学キャンパス(北海道)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] ドッキングシミュレーションに基づくGPR40アゴニストの構造活性相関2012

    • Author(s)
      Masato Takeuchi, Akira Hirasawa, Takafumi Hara, Tatsuya Hirano, Takayoshi Suzuki, Naoki Miyata, Masaji Ishiguro and Gozoh Tsujimoto
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学キャンパス内(北海道)
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] ドッキングシミュレーションに基づくGPR40アゴニストの構造活性相関2012

    • Author(s)
      Takeuchi M, Hirasawa A, Hara T, Hirano T, Suzuki T, Miyata N, Ishiguro M, Tsujimoto G
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学キャンパス内(北海道)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] 長鎖脂肪酸受容体GPR120の生理機能の解明と創薬応用2012

    • Author(s)
      平澤明、辻本豪三
    • Organizer
      第85回日本内分泌学会学術総会
    • Place of Presentation
      際会議場(愛知県)
    • Year and Date
      2012-04-19
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] 長鎖脂肪酸受容体GPR120の生理機能の解明と創薬応用2012

    • Author(s)
      平澤明
    • Organizer
      第85回日本内分泌学会学術総会
    • Place of Presentation
      名古屋国際会議場 (愛知県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] 脂肪酸センサーGPR120は食事性肥満の原因遺伝子である2012

    • Author(s)
      平澤明
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡 (福岡県)
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] 長鎖脂肪酸受容体 GPR120 の生理機能の解明と創薬応用2012

    • Author(s)
      平澤明
    • Organizer
      第85回日本内分泌学会学術総会招待講演
    • Place of Presentation
      愛知県名古屋国際会議場
    • Year and Date
      2012-04-19
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] 脂肪酸受容体GPR120の構造活性相関と薬理学的機能解析2012

    • Author(s)
      原貴史、平澤明、竹内理人、鮎川久美子、白井遼平、辻本豪三
    • Organizer
      第41回日本心脈管作動物質学会
    • Place of Presentation
      秋田キャッスルホテル(秋田県)
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] Structure-Activity Relationships of GPR120 Agonists Based on a Docking Simulation2011

    • Author(s)
      平澤明
    • Organizer
      AIMECS11;Frontier of Medicinal Science
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-23659038
  • [Presentation] 脂肪酸受容体GPR120機能不全は食餌誘発性の肥満及び脂肪肝を惹起する2011

    • Author(s)
      市村敦彦, 平澤明, 宮内諭, 木村郁夫, 鮎川公美子, 竹内理人, 辻本豪三
    • Organizer
      第40回心脈管作動物質学会
    • Place of Presentation
      かがわ国際会議場(高松市)
    • Year and Date
      2011-02-05
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] 糸球体腎炎におけるCK2α特異的阻害効果の検討2011

    • Author(s)
      安江美里, 劉寧, 武井義則, 侯増力, 鈴木大和, 大野浩章, 仲西功, 木下誉富, 村田克美, 北浦和夫, 平澤明, 辻本豪三
    • Organizer
      日本薬学会 第131年会
    • Place of Presentation
      ツインメッセ静岡(静岡市)
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] Structure-Activity Relationships of GPR120 Agonists Based on a Docking Simulation2011

    • Author(s)
      平澤明
    • Organizer
      AIMECS11 ; Frontier of Medicinal Science
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] Structure-activity relationships of GPR40 agonists based on a docking simulation2011

    • Author(s)
      Takeuchi M, Sun Q, Hara T, Hirasawa A, Ishiguro M, Suzuki T, Miyata N, Tsujimoto G.
    • Organizer
      第6回国際受容体シンポジウム
    • Place of Presentation
      京都大学(京都府)
    • Year and Date
      2011-04-02
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] ドッキングシミュレーションに基づくGPR40アゴニストの構造活性相関2011

    • Author(s)
      竹内理人, Qi Sun, 原貴史, 平澤明, 石黒正路, 鈴木孝禎, 宮田直樹, 辻本豪三
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2011-03-23
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] 脂肪酸受容体GPR120の代謝調節機構の解析2010

    • Author(s)
      平澤明、原貴史、市村敦彦、宮内諭、木村郁夫、輿水崇鏡、辻本豪三
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] Free fatty acid receptors and drug discovery2010

    • Author(s)
      辻本豪三, 平澤明
    • Organizer
      第42回日本動脈硬化学会学術集会
    • Place of Presentation
      長良川国際会議場(岐阜市)(招待講演)
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] トランスポゾンを用いたランダム変異・プローブ導入によるGタンパク質共役受容体の機能解析2010

    • Author(s)
      平澤明, 寺西文恵, 平井絢子, 伊津野彩子, 石田未弥, 淡路健雄, 辻本豪三
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸国際展示場(神戸市)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] 脂肪酸受容体GPR120の代謝調節機構の解析2010

    • Author(s)
      平澤明
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] GPR120 mediates high-fat diet-induced adipocyte hypertrophy and obesity2010

    • Author(s)
      市村敦彦, 平澤明, 宮内諭, 辻本豪三
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Bella Center (Copenhagen, Denmark)
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] 脂肪酸受容体GPR120の新規リガンド探索と構造活性相関2010

    • Author(s)
      原貴史, Sun Qi, 平澤明, 木村邦夫, 足達哲也, 淡路健夫, 石黒正路, 鈴木孝禎, 宮田直樹, 辻本豪三
    • Organizer
      第38回薬物活性シンポジウム・第20回日本循環薬理学会
    • Place of Presentation
      札幌市教育文化会館(札幌市)
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] 脂肪酸受容体GPR120の代謝調節機構の解析2010

    • Author(s)
      平澤明
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] トランスポゾンを用いたランダム変異導入によるタンパク質標識および機能解析法2009

    • Author(s)
      平澤明, 平井絢子, 寺西文恵, 伊津野彩子, 辻本豪三
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] Pharmacological characterization of a novel G protein-couple receptor 120-selective agonist2009

    • Author(s)
      Qi Sun, Akira Hirasawa, Takafumi Hara, Tetsuya Adachi, Mie Hata, Takayoshi Suzuki, Naoki Miyata, Gozoh Tsujimoto
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      国立京都国際会館/グランドプリンスホテル京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] 脂肪酸受容体ノックアウトマウスによる代謝疾患解析2009

    • Author(s)
      平澤明、辻本豪三
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] 消化管における脂肪酸受容と創薬2009

    • Author(s)
      平澤明, 原貴文, 市村敦彦, 劉寧, 飯田桂子, 辻本豪三
    • Organizer
      第82回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] 脂肪酸受容体ノックアウトマウスによる代謝疾患解析2009

    • Author(s)
      平澤明, 辻本豪三
    • Organizer
      第82回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] 糖尿病と脂肪酸受容体ファミリー2009

    • Author(s)
      平澤明、辻本豪三
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      国立京都国際会議場(京都府)
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] 糖尿病と脂肪酸受容体ファミリー2009

    • Author(s)
      平澤明, 辻本豪三
    • Organizer
      日本薬学会第129年会シンポジウム
    • Place of Presentation
      国立京都国際会館/グランドプリンスホテル京都
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] SS2-7消化管におけるアミノ酸・脂肪酸受容と創薬2008

    • Author(s)
      平澤明
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Presentation] SS2-7 消化管におけるアミノ酸・脂肪酸受容と創薬2008

    • Author(s)
      平澤明
    • Organizer
      目本薬学会第128年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-03-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Presentation] フローサイトメーターを用いた脂肪酸受容体(GPR40)のリガンド受容体直接相互作用の解析2008

    • Author(s)
      原 貴史、平澤 明、井坪 千怜、定金 恵子、辻本 豪三
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] FAT SENSING IN THE GUT2008

    • Author(s)
      Akira Hirasawa, Gozoh Tsujimoto
    • Organizer
      THE 18TH EUROPEAN CHEMORECEPTION RESEARCH ORGANIZATION CONGRESS, ECRO-2008
    • Place of Presentation
      Grand Hotel Bernardin, Portoroz, Slovenia
    • Year and Date
      2008-09-04
    • Data Source
      KAKENHI-PROJECT-20659011
  • [Presentation] Gut amino acid- and fatty acid-sensors targeted as a new drug discovery2008

    • Author(s)
      Hirasawa, A
    • Organizer
      Proceedings of the 128th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Pacifico Yokohama
    • Year and Date
      2008-03-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Presentation] SS2-7消化管におけるアミノ酸・脂肪酸受容と創薬2008

    • Author(s)
      平澤明
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      パシフイコ横浜
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] 遊離脂肪酸受容体における特異的抗体の作成と祖織分布の解析2007

    • Author(s)
      宮内諭, 平澤明, 井坪千怜, 輿水崇鏡, 定金惠子, 原貴史, 辻本豪三
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] 新規遊離脂肪酸受容体GPR40およびGPR120のリガンド結合様式の検討2007

    • Author(s)
      和田浩志, 平澤明, 定金恵子, 矢野武明, 原貴史, 嶽本和久, 足達哲也, 輿水崇鏡, 石黒正路, 辻本豪三
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] 遊離脂肪酸受容体に対する新規アゴニストおよびアンタゴニストの探索-Searching for specific agonists and antagonists of receptors for free fatty acids2007

    • Author(s)
      井坪千怜, 定金惠子, 橋本敏弘, 浅川義範, 平澤明, 辻本豪三
    • Organizer
      日本ケミカルバイオロジー研究会第2回年会
    • Place of Presentation
      京都大学時計台記念館(京都市)
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Presentation] 脂肪酸受容体の生理機能2007

    • Author(s)
      平澤 明
    • Organizer
      第80回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2007-03-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Presentation] 遊離脂肪酸受容体に対する新規アゴニストおよびアンタゴニストの探索2007

    • Author(s)
      井坪千怜, 定金惠子, 橋本敏弘, 浅川義範, 平澤明, 辻本豪三
    • Organizer
      日本ケミカルバイオロジー研究会第2回年会
    • Place of Presentation
      京都大学百周年時計台記念館
    • Year and Date
      2007-05-10
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] 長鎖脂肪酸のGPR120を介したアディポネクチン分泌促進作用2007

    • Author(s)
      伊賀朋世, 足達哲也, 輿水 崇鏡, 平澤 明, 辻本豪三
    • Organizer
      第17回日本循環薬理学会
    • Place of Presentation
      大阪大学医学部
    • Year and Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] Ligand identification and functional analysis for fatty acid receptor2007

    • Author(s)
      Hirasawa, A
    • Organizer
      The 80th Annual Meeting of The Japanese Pharmacological Society
    • Place of Presentation
      Nagoya Congress Center
    • Year and Date
      2007-03-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Presentation] Ligand identification and functional analysis for orphan GPCR GPR1202006

    • Author(s)
      Hirasawa, A
    • Organizer
      20th IUBMB Internatonal Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto International Conference Cent
    • Year and Date
      2006-06-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • [Presentation] Ligand identification and functional analysis for orphan GPCR GPR1202006

    • Author(s)
      Akira Hirasawa
    • Organizer
      第20回国際生化学・分子生物学会議(20th IUBMB Internatonal Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress)
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2006-06-23
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390024
  • 1.  KOSHIMIZU Taka-aki (20392491)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 21 results
  • 2.  TSUJIMOTO Gozoh (80172013)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 49 results
  • 3.  AWAJI Takeo (60297546)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 4.  ADACHI Tetsuya (60345014)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 19 results
  • 5.  OKUNO Yasushi (20283666)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  LIU Ning (70464196)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  IIDA Keiko (00422999)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  武井 義則 (30502455)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  OGATA Makiko (10233404)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TANOUE Akito (60301800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 11.  HAYANO Toshiya (90332303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OBATA TOKIO (80625244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  木村 郁夫 (80433689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 14.  寺澤 和哉 (00361569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  門脇 正史 (30378864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  徳山 尚吾 (70225358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  中本 賀寿夫 (30432636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 18.  田丸 文信 (70337541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  梶原 健 (80286103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAKADA Tatsuyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  ITO Shuji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SHINOURA Hitomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  OSHIKAWA Sayuri
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KITAGAWA Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  殊才 孝則
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  片岡 正和
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  洪 成忠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi