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MATSUZAKI Yoichiro  松崎 洋一郎

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MATSUZAKI Youichirou  松崎 洋一郎

松崎 洋一郎  マツザキ ヨウイチロウ

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Researcher Number 70282522
Affiliation (based on the past Project Information) *help 2008: 京都府立医科大学, 医学研究科, 助手
2006: 京都府立医大, 医学系研, 助手
2003 – 2005: 京都府立医科大学, 医学研究科, 助手
2000 – 2002: 京都府立医科大学, 医学部, 助手
1996 – 1997: 東京大学, 医科学研究所, 教務職員
Review Section/Research Field
Principal Investigator
Hygiene
Except Principal Investigator
Hygiene / Hygiene
Keywords
Principal Investigator
p19 / p18 / p15 / p16 / インドール-3-カービノール / HDAC阻害剤 / 酪酸 / 分子標的癌予防 / PPARγ / p15プロモーター … More / 15-d-PGJ_2 / チロシン・キナーゼ / TPA / p16、p15、p18、p19 / 癌抑制遺伝子 … More
Except Principal Investigator
gadd45 / p18 / TPA / p53 / p27 / WAF1 / p21 / ケルセチン / NF-Y / 酪酸 / p15 / TRAIL / DR5 / 癌 / p19 / プロモーター / RB / mac25 / Vitamin D_3 / 予防 / リ・フラウメニ症候群 / ゲニステイン / 細胞周期 / I3C / butyrate / ルテオリン / インドール-3-カービノール / quercetin / flavonoids / Sodium Butyrate / ビタミンD_3受容体 / mac25遺伝子 / ヒストン脱アセチル化酵素阻害剤 / フラボノイド / ビタミンD_3 / histone deacetylase inhibitor / promoter / prevention / cancer / フラボン / 紫外線 / gadd45遺伝子 / Δ^<12>-プロスタグランディンJ_2 / リ-フラウメニ症侯群 / Sp3 / Sp1 / SAHA / セストン脱アセチル化酵素阻害剤 / WAP1 / 分子標的予防 / 科学予防 / HDAC阻害 / Oct-1 / MEK / MAPK / 家族性メラノーマ / p53-RB経路 / がん / p16 / テーラーメイド予防 / 癌抑制遺伝子 / 発癌促進物質 / 発癌抑制物質 / クルクミン / PKC / アポトーシス / CDK / Siah-1 / 環境発癌要因 / 発癌プロモーター / 環境発癌因子 / 白血病 / 白血病ウイルス / 転写活性化 / HTLV-1 / ウイルス発がん / 遺伝子発現 / 転写因子 / 成人T細胞白血病 / 細胞周期阻害因子 Less
  • Research Projects

    (9 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (13 People)
  •  食品因子を用いたINK4遺伝子を分子標的とする癌予防法の開発Principal Investigator

    • Principal Investigator
      松崎 洋一郎
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  ヒト環境発癌分子を標的とした新規発癌抑制物質スクリーニング系の構築

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer prevention

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  環境発癌因子の分子標的-p16とそのファミリー遺伝子の役割について-Principal Investigator

    • Principal Investigator
      松崎 洋一郎
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  種々の環境発癌因子の標的分子の同定―「分子標的予防法」に向けての基礎的研究

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Basic research for ‘gene-regulating chemoprevention' by using food factors

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of the new cancer preventing method with the ingredient of the food of Kyoto

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for University and Society Collaboration
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  HTLV-1による遺伝子発現と細胞増殖の脱制御の研究

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Development of specific prevention against people with high susceptibility for cancer and general carcinogenesis

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation

  • [Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin DI expression.2008

    • Author(s)
      Matsuzaki Y, et al.
    • Journal Title

      Oncol Rep. 19(3)

      Pages: 721-727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.2008

    • Author(s)
      Matsuzaki Y., et. al.
    • Journal Title

      Oncology Reports 19(3)

      Pages: 721-727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression2008

    • Author(s)
      Matsuzaki Y, Koyama M, Hitomi T, Yokota T, Kawanaka M, Nishikawa A, Germain D, Sakai T
    • Journal Title

      Oncol Rep. 19

      Pages: 721-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] ZD1839 induces p15^<INK4b> and causes G1 arrest by inhibiting the MAPK/ERK pathway2007

    • Author(s)
      Koyama M, Matsuzaki Y, Yogosawa S, Hitomi T, Kawanaka M, Sakai T
    • Journal Title

      Mol Cancer Ther. 6

      Pages: 1579-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Identification of JTP-70902, a p15^<INK4b>-inductive compound, as a novel MEK1/2 inhibitor2007

    • Author(s)
      Yamaguchi T, Yoshida T, Kurachi R, Kakegawa J, Hori Y, Nanayama T, Hayakawa K, Abe H, Takagi K, Matsuzaki Y, Koyama M, Yogosawa S, Sowa Y, Yamori T, Tajima N, Sakai T
    • Journal Title

      Cancer Sci. 98

      Pages: 1809-16

    • NAID

      10020119466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells2007

    • Author(s)
      Yokota T, Matsuzaki Y(他9名), Sakai T(他9名)Sesamin
    • Journal Title

      Cancer Sci. 98

      Pages: 1447-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Oct-1 is involved in the transcriptional repression of the p15^<INK4b> gene2007

    • Author(s)
      Hitomi T, Matsuzaki Y, Yasuda S, Kawanaka M, Yogosawa S, Koyama M, Tantin D, Sakai T
    • Journal Title

      FEBS Lett. 581

      Pages: 1087-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] INK4 family-a promising target for'gene-regulating chemoprevention'and 'molecular-targeting prevention'of cancer-2005

    • Author(s)
      Matsuzaki Y, Sakai T
    • Journal Title

      Environ Health Prev Med 10

      Pages: 72-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] INK4 family-A promising target for ‘Gene-regulating chemoprevention' and ‘Molecular-targeting prevention' of cancer-.2005

    • Author(s)
      Matsuzaki Y et al.
    • Journal Title

      Environmental Health and Prevention 10

      Pages: 72-77

    • NAID

      110002703950

    • Data Source
      KAKENHI-PROJECT-16659151
  • [Journal Article] INK4 family-A promising target for ‘Gene-regulating chemoprevention' and ‘Molecular-targeting prevention' of cancer-.2005

    • Author(s)
      Matsuzaki Y. et al.
    • Journal Title

      Environ Health Prev Med 10

      Pages: 72-77

    • NAID

      110002703950

    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] 15-Deoxy-Δ^<12,14>-prostaglandin J_2 activates the expression of p15^<INK4b> gene, a cyclin-dependent kinase inhibitor2005

    • Author(s)
      Matsuzaki Y. et al.
    • Journal Title

      International Journal of Oncology 27・2

      Pages: 497-503

    • Data Source
      KAKENHI-PROJECT-16790327
  • [Journal Article] 15-deoxy-D12,14-prostaglandin J2 activates the expression of p15INK4b gene, a cyclin-dependent kinase inhibitor.2005

    • Author(s)
      Matsuzaki Y et al.
    • Journal Title

      International Journal of Oncology 27・2

      Pages: 497-503

    • Data Source
      KAKENHI-PROJECT-16659151
  • [Journal Article] 15-Deoxy-Δ^<12, 14>-prostaglandin J_2 activates the expression of p15^<INK4b> gene, a cyclin-dependent kinase inhibitor2005

    • Author(s)
      Matsuzaki Y, Koyama M, Hitomi T, Takaoka Y, Kawanaka M, Sakai T
    • Journal Title

      Int J Oncol. 27

      Pages: 497-503

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] 15-deoxy-D12,14-prostaglandin J2 activates the expression of p15INK4b gene, a cyclin-dependent kinase inhibitor.2005

    • Author(s)
      Matsuzaki Y. et al.
    • Journal Title

      Int J Oncol 27(2)

      Pages: 497-503

    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Indole-3-carbinol (I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004

    • Author(s)
      Matsuzaki, Y. et al.
    • Journal Title

      FEBS Letters 576

      Pages: 137-140

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18^<INK4c>.2004

    • Author(s)
      Matsuzaki, Y., Takaoka, Y., Hitomi, T., Nishino, H., Sakai, T.
    • Journal Title

      Oncogene 23

      Pages: 5409-5414

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Histone deacetylase inhibitors activate p19^<INK4d> gene through Sp1 site in its promoter.2004

    • Author(s)
      Yokota, T., Matsuzaki, Y., Miyazawa, K., Zindy, F., Roussel, M., Sakai, T.
    • Journal Title

      Oncogene 23

      Pages: 5340-5349

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Indole-3-carbinol(I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004

    • Author(s)
      Matsuzaki, Y., Koyama, M., Hitomi, T., Kawanaka, M., Sakai, T.
    • Journal Title

      FEBS Letters 576

      Pages: 137-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Indole-3-carbinol activates the cyclin-dependent kinase inhibitorp15 (INK4b) gene2004

    • Author(s)
      Matsuzaki Y., et al.
    • Journal Title

      FEBS Lett. 576,1-2

      Pages: 137-140

    • Data Source
      KAKENHI-PROJECT-16659151
  • [Journal Article] Trichostatin A activates p18^<INK4c> gene : Differential activation and cooperation with p19^<INK4d> gene.2004

    • Author(s)
      Yokota, T., Matsuzaki, Y., Sakai, T.
    • Journal Title

      FEBS Letters 574

      Pages: 171-175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18^<INK4c>.2004

    • Author(s)
      Matsuzaki, Y. et al.
    • Journal Title

      Oncogene 23

      Pages: 5409-5414

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Activation of protein kinase C promoter human cancer cell growth through downregulation of pl8 (INK4c)2004

    • Author(s)
      Matsuzaki Y., et al.
    • Journal Title

      Oncogene 23,31

      Pages: 5409-5414

    • Data Source
      KAKENHI-PROJECT-16659151
  • [Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregu1ation of p18^<INK4c>.2004

    • Author(s)
      Matsuzaki, Y., et al.
    • Journal Title

      Oncogene 23

      Pages: 5409-5414

    • Data Source
      KAKENHI-PROJECT-16790327
  • [Journal Article] Indole-3-carbinol (I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004

    • Author(s)
      Matsuzaki, Y., et al.
    • Journal Title

      FEBS Letters 576

      Pages: 137-140

    • Data Source
      KAKENHI-PROJECT-16790327
  • [Journal Article] p15^<INK4b> in HDAC inhibitor-induced growth arrest.2003

    • Author(s)
      Hitomi, T., Matsuzaki, Y., Yokota, T., Takaoka, Y., Sakai, T.
    • Journal Title

      FEBS Letters 554

      Pages: 347-350

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Molecular cloning and characterization of the human p19^<INK4d> gene promoter.2002

    • Author(s)
      Matsuzaki, Y. et al.
    • Journal Title

      FEBS Letters 517

      Pages: 272-276

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Molecular cloning and characterization of the human p19^<INK4d> gene promoter.2002

    • Author(s)
      Matsuzaki, Y., Miyazawa, K., Yokota, T., Hitomi, T., Yamagishi, H., Sakai, T.
    • Journal Title

      FEBS Letters 517

      Pages: 272-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Presentation] アルクチインによるサイクリンD1発現抑制2006

    • Author(s)
      松崎洋一郎, 他
    • Organizer
      第76回日本衛生学会総会
    • Place of Presentation
      山口
    • Year and Date
      2006-03-26
    • Data Source
      KAKENHI-PROJECT-17209022
  • 1.  SOWA Yoshihiro (70315935)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 2.  SAKAI Toshiyuki (20186993)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 13 results
  • 3.  YOSHIDA Tatsushi (80315936)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 4.  KAMIYAMA Jun (20257538)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  高橋 千絵 (90305574)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  YOGOSAWA Shingo (70381936)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  HORINAKA Mano (80512037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  吉田 光昭 (80012607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  鈴木 健之 (30262075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  平井 洋 (10202277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  谷村 朗 (90251446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  加藤 満雄 (70260221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NOMURA Hitoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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