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Akimoto Kazunori  秋本 和憲

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… Alternative Names

AKIMOTO Kazunori  秋本 和憲

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Researcher Number 70285104
Other IDs
Affiliation (Current) 2025: 東京理科大学, 薬学部生命創薬科学科, 教授
Affiliation (based on the past Project Information) *help 2020 – 2023: 東京理科大学, 薬学部生命創薬科学科, 教授
2015 – 2017: 東京理科大学, 薬学部生命創薬科学科, 准教授
2012 – 2015: 東京理科大学, 薬学部, 准教授
2012: 東京理科大学, 薬学部生命創薬科学科, 准教授
2011: 横浜市立大学, 大学院・医学研究科, 助教 … More
2008 – 2011: Yokohama City University, 医学部, 助教
2007: 横浜市立大学, 医学研究科, 助教
1997 – 2006: 横浜市立大学, 医学部, 助手
2004: 横浜市立大学, 医学, 助手
1999: 横浜市立大学, 医学部・第2生化学, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 47060:Clinical pharmacy-related / Functional biochemistry / Living organism molecular science / Developmental biology / Biological Sciences / Molecular biology / Cell biology
Except Principal Investigator
Human pathology / General medical chemistry / Functional biochemistry … More / Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Obstetrics and gynecology / Dermatology / Surgical dentistry / Cell biology / Living organism molecular science / Urology Less
Keywords
Principal Investigator
aPKC / 細胞極性 / 発がん / 器官形成 / 患者層別化 / 癌ゲノム医療 / ALDH1陽性乳癌幹細胞 / 公共の癌ゲノミクスデータ / 層別化 / データサイエンス手法 … More / 解糖系 / 癌幹細胞 / 公共の癌ゲノムデータ / 癌の層別化 / breast cancer / Cell polarity / 形態形成 / 細胞情報伝達機構 / 初期発生 / ジーンターゲッティング / Atypical Protein Kinase C / loxP / Cre / p70S6キナーゼ / P70S6キナーゼ … More
Except Principal Investigator
aPKC / ASIP / 細胞極性 / PAR-6 / PAR-3 / 上皮 / 非対称分裂 / ATPase / mRNA surveillance / mRNA degradation / ATPアーゼ / リン脂質キナーゼ / mRNA分離 / RNAヘリカーゼ / プロテインキナーゼ / p53 / mRNAサーベイランス / ナンセンス変異 / 子宮頸癌 / aPKCλ/ι / 前立腺癌 / 極性 / 線虫 / RNA helicase / PIK remated protein kinase / protein kinase / P53 / nonsense mutation / epithelia / 免疫組織化学 / IL-6 / 乳癌 / ドラッグリポジショニング / 非定型プロテインキナーゼ / 難治性乳がん / 抗腫瘍活性 / 浸潤 / オーラノフィン / ヘパラナーゼ / aPKC C / 子宮頸部上皮内病変 / 子宮頸部異形成 / 子宮頸がん / nonsense mutaion / RNA helices / PIK remitted protein kinas / protein kinas / NMD / ADPアーゼ / リン脂質類似キナーゼ / mRNA分解 / cell polarity / Asymmetric division / Lg1 / polarity / asymmetric cell division / C.elegans / LST / HPV / Immunohistochemistry / Cancer / GLOI / 腫瘍化 / CIN / 幹細胞 / 皮膚発癌 / 創傷治癒 / 皮膚幹細胞 / 毛包形成 / 遺伝子改変マウス / 脱毛 / 休眠 / 毛包幹細胞 / プロテインキナーゼC / 口腔がん / Cancer stem cell / 口腔扁平上皮癌 / 膵癌 / 難治癌 / 癌細胞 / IL6 / 発生・文化 / 発生・分化 / 細胞・組織 / 分化 / 発生 / シグナル伝達 / 組織 / 細胞 / 再生医学 / 癌 / 翻訳後修飾 / 複合体 / タンパク質 / プロテオミクス / aPKC λ / aPKCλ / 細胞極性制御分子 / 腫瘍学 / aPKC-PAR系 / 乳がん / 胃がん / 前立腺がん / 上皮細胞 / MDCK細胞 / 動物極 / 卵母細胞 / ツメガエル / PAR / PKC Less
  • Research Projects

    (24 results)
  • Research Products

    (138 results)
  • Co-Researchers

    (44 People)
  •  Gene expression mechanism of glycosaminoglycan-degrading enzymes in refractory breast cancer

    • Principal Investigator
      東 恭平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Tokyo University of Science
  •  Elucidation of a novel regulatory axis of glycolysis in cancer stem cells based on cancer genomics database analysisPrincipal Investigator

    • Principal Investigator
      Akimoto Kazunori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Tokyo University of Science
  •  Role of the cell polarity regulator aPKC in uterine cervical cancer and cervical intraepithelial lesion.

    • Principal Investigator
      MARUYAMA Yasuyo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yokohama City University
  •  Role of aPKC-IL6 pathway, especially in prostatic and berast cancers

    • Principal Investigator
      NAGASHIMA Yoji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Women's Medical University
  •  Mechanism for the maintenance of skin stem cells by a cell polarity protein

    • Principal Investigator
      OSADA Shin-Ichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Akita University
      Nippon Medical School
  •  Role and possibility as a therapeutic target of aPKClambda/iota in intractable cancers

    • Principal Investigator
      NAGASHIMA Yoji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Yokohama City University
  •  Overexpression of the atypical protein kinase C rambda/iota in oral squamous cell carcinoma is associated with degrees of malignancy

    • Principal Investigator
      KOIZUMI Toshiyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Yokohama City University
  •  Molecular mechanisms of the polarity-regulating signaling

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cell biology
    • Research Institution
      Yokohama City University
  •  Analysis of the molecules of cell polarity in associated with hormone

    • Principal Investigator
      KUBOTA Yoshinobu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Yokohama City University
  •  Structure and function of multifunctional protein complex regulating cell polarity

    • Principal Investigator
      KAWASAKI Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Living organism molecular science
    • Research Institution
      Yokohama City University
  •  Regulation of Cell polarity by aPKC dependent gene expressionPrincipal Investigator

    • Principal Investigator
      AKIMOTO Kazunori
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yokohama City University
  •  Impact of the aPKC/PAR system on carcinogenesis and progression.

    • Principal Investigator
      NAGASHIMA Yoji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Yokohama City University
  •  Cell Polarity Signaling and Cancer

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Molecular mechanism of mammalian mRNA surveillance

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Yokohama City University
  •  細胞極性因子aPKClの哺乳類器官形成及び病態(発がん)における役割の解析Principal Investigator

    • Principal Investigator
      秋本 和憲
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Yokohama City University
  •  Molecular mechanism of mammalian mRNA surveillance

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Yokohama City University Graduate School of Medical Science
  •  細胞極性決定因子aPKC/ASIPの哺乳類初期発生及び器官形成における役割の解析Principal Investigator

    • Principal Investigator
      秋本 和憲
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Cre/loxPシステムを用いたaPKCの哺乳類初期発生及び器官形成における役割の解析Principal Investigator

    • Principal Investigator
      秋本 和憲
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Developmental biology
    • Research Institution
      Yokohama City University
  •  Molecular mechanism of mammalian mRNA surveillance

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yokohama City University
  •  Signaling mechanism of epithelial cell-cell attachment and cell polarity.

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  脊髄動物の初期胚におけるPAR及びaPKCの動態と極性の決定機構

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Yokohama City University
  •  コンディショナルジーンターゲッティングによるaPKC群の個体レベルでの機能解析Principal Investigator

    • Principal Investigator
      秋本 和憲
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Yokohama City University
  •  Analyses of the universal molecular machinary involved in cell polarization

    • Principal Investigator
      OHNO Shigeo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional biochemistry
    • Research Institution
      Yokohama City University School of Medicine
  •  PI3-キナーゼ→aPKC群経路の標的蛋白の同定および細胞生理作用の解析Principal Investigator

    • Principal Investigator
      秋本 和憲
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Cell biology
    • Research Institution
      Yokohama City University

All 2024 2023 2022 2021 2020 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 Other

All Journal Article Presentation Book Patent

  • [Book] 月刊 「Precision Medicine」11月号 リキッドバイオプシーによるゲノム医療 情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化2021

    • Author(s)
      秋本 和憲 ・多森 翔馬 ・翁長 朝太郎・野崎 優香・本村 瞳・尾崎 綾栞・熊御雲・田畑耕治・佐藤 圭子
    • Total Pages
      4
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Book] 「Precision Medicine」臨時増刊号 ゲノム情報とオミックス情報を活用した「予防医学」 情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化2021

    • Author(s)
      秋本 和憲 ・多森 翔馬 ・翁長 朝太郎・野崎 優香・本村 瞳・尾崎 綾栞・熊御雲・田畑耕治・佐藤 圭子
    • Total Pages
      4
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Book] 月刊 「細胞」 特集 ゲノムデータを駆使した医学研究  がんゲノミクスデータ解析を起点としたがん幹細胞の生存機構の解明2021

    • Author(s)
      多森 翔馬、本村 瞳、野崎 優香、佐藤 圭子、秋本 和憲
    • Total Pages
      3
    • Publisher
      ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Book] 月刊 「細胞」 10月臨時増刊号 新規細胞死機構が制御する生体応答  がんゲノミクスデータ解析を起点としたがん幹細胞の生存機構の解明2021

    • Author(s)
      多森 翔馬、本村 瞳、野崎 優香、尾崎 綾栞、翁長朝太郎、佐藤 圭子、秋本 和憲
    • Total Pages
      3
    • Publisher
      ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Book] 図解 腫瘍薬学 第13章10 (p534-552)2020

    • Author(s)
      小茂田昌代、秋本和憲、斎藤光江
    • Total Pages
      18
    • Publisher
      南山堂
    • ISBN
      9784525721619
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Book] 図解 腫瘍薬学 6章2-3 (p130-148)2020

    • Author(s)
      秋本和憲
    • Total Pages
      18
    • Publisher
      南山堂
    • ISBN
      9784525721619
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Book] 翻訳後修飾のプロテオミクス3章翻訳後修飾解析のための試料調整3.2.組織薄切片からの試料調整2011

    • Author(s)
      秋本和憲、永坂恵子、岡山明子、川上隆雄
    • Publisher
      講談社サイエンティフィク
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Book] 6章翻訳後修飾の機能解析の方法6.8遺伝子操作マウスを用いた個体レベルでの機能解析2011

    • Author(s)
      秋本和憲、大野茂男
    • Publisher
      講談社サイエンティフィク翻訳後修飾のプロテオミクス
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes2022

    • Author(s)
      Li-Ping Liu, Dong-Xu Zheng, Zheng-Fang Xu, Hu-Cheng Zhou, Yun-Cong Wang, Hang Zhou, Jian-Yun Ge, Daisuke Sako, Mi Li, Kazunori Akimoto, Yu-Mei Li, and Yun-Wen Zheng
    • Journal Title

      Cells

      Volume: 11 Issue: 1 Pages: 70-70

    • DOI

      10.3390/cells11010070

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Journal Article] High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers2021

    • Author(s)
      ONAGA CHOTARO、TAMORI SHOMA、MOTOMURA HITOMI、OZAKI AYAKA、MATSUDA CHIKA、MATSUOKA IZUMI、FUJITA TAKUMA、NOZAKI YUKA、HARA YASUSHI、KAWANO YOHEI、HARADA YOHSUKE、SATO TSUGUMICHI、MANO YASUNARI、SATO KEIKO、AKIMOTO KAZUNORI
    • Journal Title

      Anticancer Research

      Volume: 41 Issue: 1 Pages: 43-54

    • DOI

      10.21873/anticanres.14750

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-20J11980
  • [Journal Article] Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.2021

    • Author(s)
      Motomura H, Ozaki A, Tamori S, Onaga C, Nozaki Y, Waki Y, Takasawa R, Yoshizawa K, Mano Y, Sato T, Sasaki K, Ishiguro H, Miyagi Y, Nagashima Y, Yamamoto K, Sato K, Hanawa T, Tanuma SI, Ohno S, Akimoto K
    • Journal Title

      Oncol Lett.

      Volume: 22 Issue: 1 Pages: 547-547

    • DOI

      10.3892/ol.2021.12808

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05737, KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-21K06914
  • [Journal Article] GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.2021

    • Author(s)
      Motomura H, Tamori S, Yatani MA, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Xiong Y, Harada Y, Hanawa T, Tanuma SI, Sasaki K, Ohno S, Akimoto K.
    • Journal Title

      Anticancer Res.

      Volume: 41 Issue: 12 Pages: 5959-5971

    • DOI

      10.21873/anticanres.15415

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05737, KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-21K20732
  • [Journal Article] Five Genes Associated With Survival in Patients With Lower-grade Gliomas Were Identified by Information-theoretical Analysis2020

    • Author(s)
      SATO KEIKO、TAHATA KOUJI、AKIMOTO KAZUNORI
    • Journal Title

      Anticancer Research

      Volume: 40 Issue: 5 Pages: 2777-2785

    • DOI

      10.21873/anticanres.14250

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Journal Article] High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients2020

    • Author(s)
      Nozaki Yuka、Motomura Hitomi、Tamori Shoma、Kimura Yumiko、Onaga Chotaro、Kanai Shotaro、Ishihara Yuka、Ozaki Ayaka、Hara Yasushi、Harada Yohsuke、Mano Yasunari、Sato Tsugumichi、Sato Keiko、Sasaki Kazunori、Ishiguro Hitoshi、Ohno Shigeo、Akimoto Kazunori
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 7 Pages: e0235747-e0235747

    • DOI

      10.1371/journal.pone.0235747

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-20J11980
  • [Journal Article] Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line2020

    • Author(s)
      Kobayashi Masaki、Ishizaki Yuka、Owaki Mika、Matsumoto Yoko、Kakiyama Yuri、Hoshino Shunsuke、Tagawa Ryoma、Sudo Yuka、Okita Naoyuki、Akimoto Kazunori、Higami Yoshikazu
    • Journal Title

      Oncotarget

      Volume: 11 Issue: 18 Pages: 1653-1665

    • DOI

      10.18632/oncotarget.27581

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11119, KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-20K19686
  • [Journal Article] Aberrant Expression of the Cell Polarity Regulator aPKCλ/ι is Associated With Disease Progression in Cer2016

    • Author(s)
      Mizushima T, Asai-Sato M, Akimoto K, Nagashima Y, Taguri M, Sasaki K, Nakaya MA, Asano R, Tokinaga A, Kiyono T, Hirahara F, Ohno S, Miyagi E.
    • Journal Title

      Int J Gynecol Pathol.

      Volume: 35 Issue: 2 Pages: 106-17

    • DOI

      10.1097/pgp.0000000000000228

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08138, KAKENHI-PROJECT-15K10725, KAKENHI-PROJECT-26460456, KAKENHI-PROJECT-24590237, KAKENHI-PROJECT-25462602, KAKENHI-PROJECT-16K19041
  • [Journal Article] Atypical protein kinase C isoform, aPKCλ, is Essential for Maintaining Hair Follicle Stem Cell Quiescence2015

    • Author(s)
      Shin-Ichi Osada, Naoko Minematsu, Fumino Oda, Kazunori Akimoto, Seiji Kawana and Shigeo Ohno
    • Journal Title

      J Invest Dermatol

      Volume: 未定

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591669
  • [Journal Article] Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C λ/ι, E-cadherin, beta-catenin and basement membrane component.2014

    • Author(s)
      chikawa Y, Nagashima Y, Morioka K, Akimoto K, Kojima Y, Ishikawa T, Goto A, Kobayashi N, Watanabe K, Ota M, Fujii S, Kawamata M, Takagawa R, Kunizaki C, Takahashi H, Nakajima A, Maeda S, Shimada H, Inayama Y, Ohno S, Endo I.
    • Journal Title

      Oncol Lett

      Volume: 8 Pages: 977-984

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460456
  • [Journal Article] Proteomic analysis of proteins related to prognosis of lung adenocarcinoma.2014

    • Author(s)
      Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
    • Journal Title

      J Proteome Res

      Volume: 13 Issue: 11 Pages: 4686-464

    • DOI

      10.1021/pr4012969

    • NAID

      130005454677

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460456, KAKENHI-PROJECT-221S0001
  • [Journal Article] aPKClambda/iota is a beneficial prognostic marker for pancreatic neoplasms.2013

    • Author(s)
      Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kubota K, Kobayashi N, Hosono K, Watanabe S, Sekino Y, Sato T, Sasaki K, Nakaigawa N, Kubota Y, Inayama Y, Endo I, Ohno S, Maeda S, Nakajima A
    • Journal Title

      Pancreatology

      Volume: 13 Issue: 4 Pages: 360-8

    • DOI

      10.1016/j.pan.2013.05.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-24790714
  • [Journal Article] High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis2013

    • Author(s)
      Y. Yoshihama, Y. Izumisawa, K. Akimoto, Y. Satoh, T. Mizushima, K. Satoh, K. Chida, R. Takagawa, H. Akiyama, Y. Ichikawa, C. Kunisaki, Y. Inayama, I. Endo, Y. Nagashima and S. Ohno
    • Journal Title

      Cancer Sci

      Volume: 104 Issue: 2 Pages: 259-65

    • DOI

      10.1111/cas.12066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429
  • [Journal Article] The co-expression of aPKCλ/ιand IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J-y, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Cancer Sci

      Volume: 102(8) Pages: 1576-1581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Journal Article] The co-expression of aPKCλ/ιand IL-6 in prostate cancer tissue correlates with biochemical recurrence2011

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano JY, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Cancer Science

      Volume: 102(8) Pages: 1576-81

    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence2011

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y and Uemura H
    • Journal Title

      Cancer Science

      Volume: 102 Issue: 8 Pages: 1576-1581

    • DOI

      10.1111/j.1349-7006.2011.01972.x

    • NAID

      10030242512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-23791798
  • [Journal Article] The co-expression of aPKCλ/ιand IL-6 in prostate cancer tissue correlates with biochemical recurrence2011

    • Author(s)
      Ishiguro H, Akimoto K, et al.
    • Journal Title

      Cancer Science

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Cancer Science

      Volume: 102(8) Pages: 1576-1581

    • NAID

      10030242512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano JY, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Cancer Science

      Volume: (In press)

    • NAID

      10030242512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence2011

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J-y, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Cancer Sci

      Volume: 102(8) Pages: 1576-1581

    • NAID

      10030242512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] High expression of the atypical protein kinase C λ/ι in gastric cancer is promising prognostic factor for recurrence.2010

    • Author(s)
      Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Endo I, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Nagashima Y, Ohno S
    • Journal Title

      Ann Surg Oncol 17(1)

      Pages: 81-88

    • Data Source
      KAKENHI-PROJECT-20590368
  • [Journal Article] High expression of atypical protein kinase C l/I in gastric cancer as a prognositic factor for recurrence2010

    • Author(s)
      Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S
    • Journal Title

      Annals of Surgical Oncology

      Volume: 17(1) Pages: 81-88

    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] High Expression of Atypical Protein Kinase C λ/.in Gastric Cancer as a Prognostic Factor for Recurrence2010

    • Author(s)
      Takagawa R., Akimoto K.(全12名中2番目), Ishiguro H. (全12名中7番目), Nagashima Y. (全12名中11番目)
    • Journal Title

      Ann Surg Oncol 17

      Pages: 81-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] A cell polarity protein aPKC1ambda is required for eye lens formation and growth.2009

    • Author(s)
      Sugiyama Y, Akimoto K, Robinson M.L, Ohno S, Qinlan R.A
    • Journal Title

      Dev Biol 336(2)

      Pages: 246-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth.2009

    • Author(s)
      Sugiyama Y, Akimoto K, Robinson M L, Ohno S, Quinlan R A
    • Journal Title

      Dev Biol 336(2)

      Pages: 246-256

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Proc Natl Acad Sci USA 106(38)

      Pages: 16369-16374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth2009

    • Author(s)
      Sugiyama Y, Akimoto K, et al.
    • Journal Title

      Developmental Biology 336(2)

      Pages: 246-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Proc Natl Acad Sci U S A 106(38)

      Pages: 16369-16374

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] A cell polarity protein aPKC lambda is required for eye lens formation and growth2009

    • Author(s)
      Sugiyama Y., Akimoto K., Robinson M. L., Ohno S., Quinlan R.
    • Journal Title

      A.Dev Biol 336

      Pages: 246-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth2009

    • Author(s)
      Sugiyama Y, Akimoto K, Robinson M. L, Ohno S, Quinlan R. A
    • Journal Title

      Dev Biol

      Volume: 336(2) Pages: 246-256

    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.2009

    • Author(s)
      Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
    • Journal Title

      PLoS ONE 4(1)

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] aPKCλ/ι promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Pro Natl Acad Sci USA 106(38)

      Pages: 16369-16374

    • Data Source
      KAKENHI-PROJECT-20590368
  • [Journal Article] The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors.2009

    • Author(s)
      Kojima Y, Akimoto K, Nagashima Y, Ishiguro H(その他11名)
    • Journal Title

      Hum Pathol 39

      Pages: 824-831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] aPKCλ/. promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-62009

    • Author(s)
      Ishiguro H., Akimoto K., Nagashima Y.,(その他7名)
    • Journal Title

      Proc. Natl. Acad. Sci. USA 106

      Pages: 16369-16374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms2009

    • Author(s)
      Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
    • Journal Title

      PLoS ONE

      Volume: 4(1)

    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] High expression of atypical protein kinase C lambda/iota in gastric cancer as aprognostic factor for recurrence.2009

    • Author(s)
      Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Ngashima Y, Ohno S
    • Journal Title

      Ann Surg Oncol 17(1)

      Pages: 81-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms2009

    • Author(s)
      Hirose T, Satoh D, KuriharaH, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
    • Journal Title

      PLoS ONE 4(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] An essential role of the universal polarity protein, aPKC1ambda, on the maintenance of podocyte slit diaphragms.2009

    • Author(s)
      Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
    • Journal Title

      PLoS ONE 4(1)

      Pages: 4194-4194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.2009

    • Author(s)
      Hirose T, Akimoto K(全10名中6番目)
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence.2009

    • Author(s)
      Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S
    • Journal Title

      Ann Surg Oncol 17(1)

      Pages: 81-88

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] PKCλ/ιpromotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-62009

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki Y, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Proceedings of the National Academy of Sciences(PNAS)

      Volume: 106(38) Pages: 16369-16374

    • Data Source
      KAKENHI-PROJECT-21390443
  • [Journal Article] The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors2008

    • Author(s)
      Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ichikawa T, Sasaki T, Kubota Y, InayamaY, Aoki I, Ohno S, Shimada H
    • Journal Title

      Hum Pathol 39(6)

      Pages: 824-831

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] Collecting duct carcinoma of the kidney : an immunohistochemical evaluation of the use of antibodies for differential diagnosis.2008

    • Author(s)
      Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Kobayashi N, Matsuzaki O, Shirai S, Aoki I, Yao M, Shima H
    • Journal Title

      Hum Pathol 39(9)

      Pages: 1350-1359

    • Data Source
      KAKENHI-PROJECT-20590368
  • [Journal Article] The over- expression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors.2008

    • Author(s)
      Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ishikawa T, Sasaki T, Kubota Y, Inayama Y, Aoki I, Ohno S, Shimada H
    • Journal Title

      Hum Pathol 39(6)

      Pages: 824-831

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] Inactivation of aPKC λ results in a loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.2006

    • Author(s)
      Imai F, Hirai S-I, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
    • Journal Title

      Development 133(9)

      Pages: 1735-1744

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] Inactivation of aPKCλresults in a loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.2006

    • Author(s)
      Imai F, Hirai S-I, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
    • Journal Title

      Development 133(9)

      Pages: 1735-1744

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.2006

    • Author(s)
      Hirose T, Karasawa M, Sugitani Y, Fujisawa M, Akimoto K, Ohno S, Noda T
    • Journal Title

      Development 133(7)

      Pages: 1389-1398

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] Function of aPKClambda in differentiating photoreceptors is required for proper lamination of mouse retina.2005

    • Author(s)
      Koike C, Nishida A, Akimoto K, Nakaya M-A, Noda T, Ohno S, Furukawa T
    • Journal Title

      J.Neurosci. 25(44)

      Pages: 10290-10298

    • Data Source
      KAKENHI-PROJECT-17014076
  • [Journal Article] Protein Kinase Cl/i (PKCl/i): A PKC isotype essential for the development of multicellular organisms2003

    • Author(s)
      Suzuki, A., Akimoto, K., Ohno, S.
    • Journal Title

      J. Biochemistry 133

      Pages: 9-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209013
  • [Journal Article] Protein kinase C 1/I (PKC 1/I): aPKC isotype essential for the development of multicellular organism.2003

    • Author(s)
      Suzuki A, Akimoto K, Ohno S
    • Journal Title

      J.Biochem (Tokyo) 133(1)

      Pages: 9-16

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209013
  • [Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J-y, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Journal Title

      Cancer Sci in press

    • NAID

      10030242512

    • Data Source
      KAKENHI-PROJECT-20590368
  • [Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y(その他10名)
    • Journal Title

      Cancer Sci in press

    • NAID

      10030242512

    • Data Source
      KAKENHI-PROJECT-20570138
  • [Journal Article] The overexpression and altered localization of the atypical Protein Kinase C lambda/iota in breast cancer correlates with the pathological type of these tumors

    • Author(s)
      Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Insiakama T, Sasaki T, Knbota Y, Knbota Y, Inayama Y, Aoki I, Ohno S, Shimada H
    • Journal Title

      Human Pathology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Patent] 初期乳癌の検出方法2011

    • Inventor(s)
      秋本和憲、川崎博史、平野久、大野茂男、長嶋洋治
    • Industrial Property Rights Holder
      公立大学法人横浜市立大学
    • Industrial Property Number
      2011-044047
    • Filing Date
      2011-03-01
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Patent] 初期乳がんモデル用動物2009

    • Inventor(s)
      秋本和憲、大野茂男
    • Industrial Property Rights Holder
      公立大学法人横浜市立大学
    • Industrial Property Number
      2009-145675
    • Filing Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Patent] 初期乳がんモデル用動物2009

    • Inventor(s)
      秋本和憲, 大野茂男
    • Industrial Property Rights Holder
      公立大学法人横浜市立大学
    • Industrial Property Number
      2009-145675
    • Filing Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Patent] 初期乳がんモデル用動物2009

    • Inventor(s)
      秋本和憲、大野茂男
    • Industrial Property Rights Holder
      公立大学法人横浜市立大学
    • Filing Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Patent] 初期乳がんモデル用動物2007

    • Inventor(s)
      秋本和憲、野田哲生、大野茂男
    • Industrial Property Rights Holder
      横浜市立大学
    • Industrial Property Number
      2007-167036
    • Filing Date
      2007-06-25
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] 乳がん由来細胞株の浸潤能とグリコサミノグリカン構造および関連タンパク質との相関関係2024

    • Author(s)
      勝本祥央、宮嶋倫、米野雅大、渡辺怜央、多森翔馬、秋本和憲、東伸昭、戸井田敏彦、東恭平
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K06139
  • [Presentation] オーラノフィンはヘパラナーゼ生合成を阻害することで乳がん細胞株の浸潤を抑制する2024

    • Author(s)
      宮嶋倫、宮下佳那美、米野雅大、三輪有由奈、多森翔馬、小谷仁司、寺島裕也、秋本和憲、東伸昭、須田貴司、東恭平
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K06139
  • [Presentation] ヘパラナーゼ遺伝子の発現を抑制する既存薬の同定2023

    • Author(s)
      宮嶋 倫、宮下 佳那美、米野 雅大、三輪 有由奈、多森 翔馬、小谷 仁司、秋本 和憲、東 伸昭、須田 貴司、東 恭平
    • Organizer
      第42回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-23K06139
  • [Presentation] がんゲノミクスデータ解析を起点とした無機リン酸共輸送体SLC20A1のALDH1陽性膵臓がん幹細胞における役割解析2022

    • Author(s)
      松岡 泉、翁長 朝太郎、多森 翔馬、石井 雅貴、佐藤 圭子、佐々木 和教、大野 茂男、秋本 和憲
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] p62とALDH1A3遺伝子共高発現Luminal B型乳癌は予後不良である2022

    • Author(s)
      尾崎 綾栞、多森 翔馬、本村 瞳、翁長 朝太郎、長島 佑夏、小鳥 真歩、松田 あかり、望月菜々子、佐々木 和教、大野 茂男、秋本 和憲
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] がんゲノミクスデータ解析によるProtein Kinase C ζ(PKCζ)の乳がん幹細胞における役割の解析2022

    • Author(s)
      長島 佑夏、多森 翔馬、本村 瞳、尾﨑 綾栞、翁長 朝太郎、佐々木 和教、大野 茂男、秋本 和憲
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] Glyoxalase 1 and protein kinase Cl as potential therapeutic targets for late-stage breast cancer2021

    • Author(s)
      Motomura H., Ozaki A., Tamori S., Onaga C., Nozaki Y., Akimoto K.
    • Organizer
      International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] High SLC20A1 expression is associated with poor prognosis in claudin-low and basal-like breast cancers2021

    • Author(s)
      Onaga C., Tamori S., Motomura H., Ozaki A., Matsuda C., Matsuoka I., Fujita T., Nozaki Y., Hara Y., Kawano Y., Harada Y., Sato T., Mano Y., Sato K., Akimoto K.
    • Organizer
      International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] High PKCλ expression is required for asymmetric cell division of ALDH1-positive cancer stem cells and indicates poor clinical outcome in late-stage breast cancer patients2021

    • Author(s)
      Tamori S., Nozaki Y., Motomura H., Onaga C., Ozaki A., Sasaki K., Ohno S., Akimoto K.
    • Organizer
      International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer2021

    • Author(s)
      Hitomi Motomura-Shiina*, Ayaka Ozaki, Shoma Tamori, Chotaro Onaga, Yuka Nozaki and Kazunori Akimoto
    • Organizer
      7TH EDITION - WEBINAR ON BREAST CANCER
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] High p62 and ALDH1A3 expressions are associated with poor prognosis in luminal B breast cancer2021

    • Author(s)
      Ozaki A., Motomura H., Tamori S., Onaga C., Matsuda C., Matsuda A., Mochizuki N., Sasaki K., Ohno S., Akimoto K.
    • Organizer
      International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] Claudin-low型、Basal-like型乳がんにおけるSLC20A1高発現は乳がん患者の予後不良に関与する High SLC20A1 Expression is Associated with Poor Prognoses in Claudin-low and Basal-like Breast Cancers2021

    • Author(s)
      翁長 朝太郎、多森 翔馬、本村 瞳、尾﨑 綾栞、松田 千佳、松岡 泉、藤田 拓真、野崎 優香、原 泰志、河野 洋平、原田 陽介、佐藤 嗣道、真野 泰成、佐藤 圭子、秋本 和憲
    • Organizer
      第141回 日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] TNBC型乳癌においてPKCλとGATA4のタンパク質発現は逆相関し、PKCλタンパク質高発現かつGATA4タンパク質低発現患者は予後不良である Inverse correlation between PKCλ and GATA4 at protein level indicates poorer clinical outcomes in TNBC patients2021

    • Author(s)
      尾崎 綾栞、多森 翔馬、今岡 宏太朗、山口 淳三、樋上 賀一、秋本 和憲
    • Organizer
      第141回 日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] PKCλ高発現はALDH1A3陽性乳癌幹細胞の非対称分裂能に関与する High PKCλ expression is required for asymmetric cell division of ALDH1A3-positive breast cancer stem cell2021

    • Author(s)
      多森 翔馬、野崎 優香、本村 瞳、翁長 朝太郎、尾﨑 綾栞、佐々木 和教、大野 茂男、秋本 和憲
    • Organizer
      第141回 日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] ステージIII-IV乳癌におけるGLO 1 - PKCλ共発現患者は予後不良である Correlation between Glyoxalase 1 and Protein kinase C λ is predictive of poor clinical outcomes in late-stage breast cancer2021

    • Author(s)
      本村 瞳、尾﨑 綾栞、多森 翔馬、翁長 朝太郎、野崎 優香、和氣 由布子、高澤 涼子、吉澤 一巳、真野 泰成、佐藤 嗣道、佐々木 和教、石黒 斉、宮城 洋平、長嶋 洋治、山本 紘司、佐藤 圭子、花輪 剛久、田沼 靖一、大野 茂男、秋本 和憲
    • Organizer
      第141回 日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer2021

    • Author(s)
      本村 瞳、尾崎 綾栞、多森 翔馬、野崎 優香、高澤 涼子、佐々木 和教、石黒 斉、宮城 洋平、長嶋 洋治、田沼 靖一、大野 茂男、秋本 和憲
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] ステージⅢ-Ⅳ乳癌におけるc-Met, PKC λ , ALDH1A3共発現患者は予後不良である2020

    • Author(s)
      本村瞳、野崎優香、翁長朝太郎、尾﨑綾栞、多森翔馬、秋本和憲
    • Organizer
      第64回 日本薬学会 関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] TNBC型乳癌におけるPKC λ とGATA4の免疫組織学的解析2020

    • Author(s)
      尾崎綾栞、多森翔馬、今岡宏太朗、山口淳三、樋上賀一、秋本和憲
    • Organizer
      第64回 日本薬学会 関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] Correlation between Glyoxalase 1 and PKCλ is predictive of poor clinical outcomes in late-stage breast cancer ステージIII-IV乳癌におけるGLO 1 - PKCλ共発現患者は予後不良である2020

    • Author(s)
      本村 瞳、尾崎 綾栞、多森 翔馬、野崎 優香、高澤 涼子、佐々木 和教、石黒 斉、宮城 洋平、長嶋 洋治、田沼 靖一、大野 茂男、秋本 和憲
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] 乳がんゲノムデータベースを用いたSLC20A1遺伝子発現と予後の検討2020

    • Author(s)
      翁長朝太郎、多森翔馬、本村瞳、藤田拓真、真野泰成、佐藤嗣道、田畑耕司、佐藤圭子、秋本和憲
    • Organizer
      第64回 日本薬学会 関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K07207
  • [Presentation] ヒト乳癌におけるAtypical protein kinase C (aPKC)λ/ιと糖代謝機構との関連2016

    • Author(s)
      本村瞳, 片山鈴花, 多森翔馬, 松村将史, 柳川拓哉, 和氣由布子, 高澤涼子, 田沼靖一, 宮城洋平, 長嶋洋治, 今井美沙, 佐藤圭子, 秋本和憲
    • Organizer
      第136回日本薬学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市西区)
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26460456
  • [Presentation] 細胞極性因子aPKCλは毛包幹細胞の維持に必要である2014

    • Author(s)
      長田真一,峰松直子,小田文乃,秋本和憲,川名誠司,眞鍋 求,大野茂男
    • Organizer
      第22回毛髪科学研究会
    • Place of Presentation
      東京
    • Year and Date
      2014-11-29
    • Data Source
      KAKENHI-PROJECT-24591669
  • [Presentation] The Roles of aPKCλin Maintaining Epidermal Homeostasis2014

    • Author(s)
      長田真一,峰松直子,小田文乃,秋本和憲,川名誠司,眞鍋 求,大野茂男
    • Organizer
      第38回表皮細胞研究会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-24591669
  • [Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis2012

    • Author(s)
      水島大一, 秋本和憲, 長嶋洋治, 最上多恵, 佐藤美紀子, 宮城悦子, 亀田陽一, 稲山嘉明, 大橋健一, 青木一郎, 大野茂男, 平原史樹
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      北海道,札幌市,ロイトン札幌
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻2012

    • Author(s)
      秋本和憲, 長嶋洋治, 石黒斉, 鄭允文, 佐々木和教, 谷口英樹, 野田哲生, 大野茂男
    • Organizer
      第30回日本ヒト細胞学会学術集会シンポジウム
    • Place of Presentation
      大阪府,大阪市,梅田スカイビル
    • Year and Date
      2012-08-19
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻.2012

    • Author(s)
      秋本和憲, 長嶋洋治, 石黒 斉, 鄭 允文, 佐々木和教, 谷口英樹, 野田哲生, 大野茂男
    • Organizer
      第30回日本ヒト細胞学会学術集会シンポジウム
    • Place of Presentation
      梅田スカイビル(大阪府)
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] Prognostic impact of aPKCλ/ιexpression in pancreatic cancer2011

    • Author(s)
      加藤真吾, 秋本和憲, 長嶋洋治, 石黒斉, 古林規敏, 前田慎, 大野茂男, 中島淳
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      愛知県,名古屋市,名古屋国際会議場
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] aPKCλ/ιregulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer2011

    • Author(s)
      秋本和憲, 長嶋洋治, 石黒斉, 鄭允文, 佐々木和教, 小島康幸, 谷口英樹, 大野茂男, 野田哲生
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      愛知県,名古屋市,名古屋国際会議場
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] In laterally spreading type tumors (LSTs) of the colon or the rectum, expression of the atypical protein kinase C lambda/iota is correlated to expression of beta-catenin and type IV collagen.2011

    • Author(s)
      Ichikawa Y, Ishikawa T, Shimizu D, Goto A, Shimamura T, Suwa H, Tatsumi K, Watanabe K, Ota M, Fujii S, Kawamata M, Akimoto K, Nagashima Y, Takahashi H, Nakajima A, Ohno S, Endo I
    • Organizer
      The 102nd Annual Meeting of American Assiciation for Cancer Research,
    • Place of Presentation
      Orange County Convention Center, Orland, Florida, USA
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] aPKCλ/ι regulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer.2011

    • Author(s)
      秋本和憲、長嶋洋治,石黒斉,鄭允文,佐々木和教,小島康幸,谷口英樹、大野茂男、野田哲生
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] 口腔扁平上皮癌におけるaPKCλ/ι過剰発現の臨床病理学的意義2011

    • Author(s)
      馬場隼一,秋本和憲,長嶋洋治,石黒 斉,來生 知,光藤健司,稲山嘉明,青木一郎,大野茂男,藤内 祝
    • Organizer
      第35回日本頭頸部癌学会
    • Place of Presentation
      ウインクあいち(愛知県)
    • Data Source
      KAKENHI-PROJECT-23592972
  • [Presentation] Prognostic impact of aPKCλ/ι expression in pancreatic cancer.2011

    • Author(s)
      加藤真吾,秋本和憲,長嶋洋治,石黒斉,古林規敏,前田慎,大野茂男,中島淳
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] Atypical protein kinase Cλ/ιregulates mouse mammary progenitor cell propagation2010

    • Author(s)
      Akimoto K, Zheng Y-W, Nagashima Y, Ishiguro H, Asai-Sato M, Kojima Y, Li B, Sasaki K, Kagawa E, Kim M, Taniguchi H, Noda T, and Ohno S
    • Organizer
      6th International Symposium on Hormonal Oncogenesis
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Presentation] 細胞極性因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010

    • Author(s)
      秋本和憲, 他
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Year and Date
      2010-10-07
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] In laterally spreading type tumors(LSTs) of the colon or the rectum, expression of the atypical protein kinase C lambda/iota is correlated to expression of beta-catenin and type IV collagen2010

    • Author(s)
      Ichikawa Y, Ishikawa T, Shimizu D, Goto A, Shimamura T, Suwa H, Tatsumi K, Watanabe K, Ota M, Fujii S, Kawamata M, Akimoto K, Nagashima Y, Takahashi H, Nakajima A, Ohno S, Endo I
    • Organizer
      The 102nd Annual Meeting of American Assiciation for Cancer Research,(Orland, FL)
    • Place of Presentation
      Orland, FL
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Sasaki K, Fujinami K, Aoki I, Ohno S, Kubota Y, Uemura H
    • Organizer
      The 69th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Osaka International Convention Center
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] 細胞極性によるHippo経路の抑制がマウス着床前胚における位置依存的な細胞分化をつかさどる2010

    • Author(s)
      平手良和, 平原志乃, 井上健一, 中尾和貴, 鈴木厚, 秋本和憲, 大野茂男, 平井孝明, 千田和広, Marikawa Y, Vernadeth A, 佐々木洋
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(ポスター発表)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010

    • Author(s)
      Ishiguro H, Akimoto K, et al.
    • Organizer
      The 69th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Osaka Osaka International Convention Center
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010

    • Author(s)
      石黒斉, 秋本和憲, 長嶋洋治, 加川絵理子, 佐々木毅, 佐野仁勇, 高川亮, 佐々木和教, 藤浪潔, 青木一郎, 大野茂男, 窪田吉信, 上村博司
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] 細胞極性制御因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010

    • Author(s)
      秋本和憲, 鄭允文, 長嶋洋治, 石黒斉, 佐々木和教, 金民大, 李斌, 角和卓, 谷口英樹, 野田哲生, 大野茂男
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] 細胞極性制御因子aPKC λによる上皮前駆細胞の増殖制御とその破綻2010

    • Author(s)
      秋本和憲, ら
    • Organizer
      第83回日本生化学会大会合同大会
    • Place of Presentation
      兵庫県 神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] 細胞極性制御因子 aPKCλによる上皮前駆細胞の増殖制御とその破綻2010

    • Author(s)
      秋本和憲, ら
    • Organizer
      第83回日本生化学会大会 合同大会
    • Place of Presentation
      兵庫県 神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] 細胞極性因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010

    • Author(s)
      秋本和憲, 鄭允文, 長嶋洋治, 石黒斉, 佐々木和教, 金民大, 李文武, 角和卓, 谷口英樹, 野田哲生, 大野茂男
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同大会 ワークショップ「上皮細胞の機能とその破綻がもたらす病態のメカニズム」
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] Atypical Protein Kinase Cλ Regulates Mouse Mammary Progenitor Cell Propagation.2010

    • Author(s)
      秋本和憲
    • Organizer
      Sixth International Symposium on Hormonal Oncogenesis
    • Place of Presentation
      Chiba SHERATON GRANDE TOKYO BAY HOTEL
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] 細胞極性によるHippo経路の抑制がマウス着床前胚における位置依存的な細胞分化をつかさどる2010

    • Author(s)
      平手良和, 平原志乃, 井上健一, 中尾和貴, 鈴木厚, 秋本和憲, 大野茂男, 平井孝明, 千田和広, Marikawa Y, Vernadeth A, 佐々木洋
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(口頭発表)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] Atypical protein kinase Cλ/ι regulates mouse mammary progenitor cell propagation.2010

    • Author(s)
      Akimoto K, Zheng Y-W, Nagashima Y, Ishiguro H, Asai-Sato M, Kojima Y, Li B, Sasaki K, Kagawa E, Kim M, Taniguchi H, Noda T, Ohno S
    • Organizer
      6th International Symposium on Hormonal Oncogenesis
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] Atypical protein kinase Cλ/ιregulates mouse mammary progenitor cell propagation.2010

    • Author(s)
      Akimoto K, et.al.
    • Organizer
      6th International Symposium on Hormonal Oncogenesis
    • Place of Presentation
      シェラトン・グランデ・トーキョーベイ・ホテル(千葉)
    • Year and Date
      2010-09-12
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] Atypical protein kinase Cλ/ιregulates mouse mammary progenitor cell propagation.2010

    • Author(s)
      Akimoto K, Zheng Y-W, Nagashima Y, Ishiguro H, Asai-Sato M, Kim M, Taniguchi H, Noda T, Ohno S., et al.
    • Organizer
      6th International Symposium on Hormonal Oncogenesis
    • Place of Presentation
      千葉県浦安市, シェラトン・グランデ・トーキョーベイホテル
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-21390443
  • [Presentation] Clinical significance of typical protein kinase iota expression in gastric cancer.2009

    • Author(s)
      Takagawa R, Nagashima Y, Akimoto K, Akiyama H, Ono H, Kimura J, Ichikawa Y, Endo I
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] The overexpression of the atypical protein kinase C λ/ι in malignant melanoma correlates with its undifferentiation and metastatic ability.2009

    • Author(s)
      Miwa H., Akimoto K., et al.
    • Organizer
      The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Hakata, JAL Resort Sea Hawk Hotel Fukuoka
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] Expression of the atypical protein kinase C in lateral spreading type tumors of the colon or the rectum.2009

    • Author(s)
      Ichikawa Y, Kojima Y, Ishikawa T, Shimizu D, Goto A, Hirokawa S, Kijima M, Yamamoto H, Suwa H, Yamagishi S, Osada S, Ota M, Fujii S, Endo I, Shimada H, Akimoto K, Nagashima Y, Ohno S
    • Organizer
      100th Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Denver
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] The overexpression of the atypical protein kinase C λ/ι in malignant melanoma correlates with its undifferentiation state and metastatic ability.2009

    • Author(s)
      Miwa H, Akimoto K, Inoue Y, Wada H, Ishiguro H, Ohno S, Nagashima Y, Ikezawa Z
    • Organizer
      34th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] Expression of the atypical protein kinase C in lateral spreading type tumors of the colon or the rectum.2009

    • Author(s)
      Ichikawa Y, Kojima Y, Nagashima Y, Akimoto K, Ishikawa T, Goto A, Hirokawa S, Yamagishi S, Ota M, Fujii S, Nakajima A, Endo I, Ohno S
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] 前立腺癌におけるaPKCの発現と前立腺癌進展機構2009

    • Author(s)
      石黒斉, 秋本和憲, 長嶋洋治, 小島康幸, 佐々木毅, 上村博司, 大野茂男, 窪田吉信
    • Organizer
      第97回日本泌尿器科学会総会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] aPKCλ regulates mammary-gland morphogenesis through the transcriptional suppression of ErbB2/HER-2 gene2008

    • Author(s)
      秋本和憲
    • Organizer
      Second JCA-AACR Special Joint Conference The Latest Advances in Breast Cancer Research
    • Place of Presentation
      兵庫県立 淡路夢舞台国際会議場
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] The cell polarity protein aPKCλ plays a critical role in the maintenance of podocyte slit diaphragms2008

    • Author(s)
      Hirose T, Satoh D, Kurihara H, Akimoto K, Matsusaka T, Ichikawa I, Noda, T, Ohno S
    • Organizer
      The 7th International Podocyte Conference
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] The role of aPKC lambda in prostate cancer progression.2008

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Uenura H, Ohno S, Kubota Y
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20590368
  • [Presentation] Conditional depletion of aPKCλ in eye lens causes microphthalmia and cataract2008

    • Author(s)
      Sugiyama Y, Akimoto K, Robinson M. L, Quinlan, R. A, Ohno S
    • Organizer
      ARVO (Association for Research in Vision and Ophthalmology) 2008Annual Meeting, 2008
    • Place of Presentation
      Florida USA
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] The role of aPKC lambda in prostate cancer progression2008

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Umemura H, Ohno S, Kubota Y
    • Organizer
      The 67th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] The cell polarity protein, aPKClambda, plays a critical rolein the maintenance of podocyte slit diaphragms, specific type if epithelial intercellular junctions2008

    • Author(s)
      Hirose T, Satoh D, Kurihara H, kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
    • Organizer
      BMB2008
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] aPKCλ regulates mammary-gland morphogenesis through the transcriptional suppression of ErbB2/HER-2 gene2008

    • Author(s)
      秋本和憲, et al.
    • Organizer
      Second JCA-AACR Special Joint Conference The Latest Advances in Breast Cancer Research.
    • Place of Presentation
      兵庫県立 淡路夢舞台国際会議場
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-20570138
  • [Presentation] aPKC1 regulates mammary-gland morphogenesis through the transcriptiona 1 suppression of ErbB2/HER-2 gene2008

    • Author(s)
      Akimoto K, Nagashima K, Ishiguro H, Kojima Y, Kim M, Sasaki K, Noda T, Ohno S
    • Organizer
      Second JCA-AACR Special Joint Conference, The Latest Advances in Breast Cancer Research : From Basic Science to Therapeutics
    • Place of Presentation
      Awaji, Hyogo, Japan
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] The role of apkcl in breast cancer2007

    • Author(s)
      Akimoto K
    • Organizer
      Yokohama City University 21st Century COE Program, Cell Polarity 2007-International symposium on CellPolarity Ststem and Future Medicine
    • Place of Presentation
      Hayama
    • Year and Date
      2007-12-09
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] aPKC role in prostatic cancer progression2007

    • Author(s)
      Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Uemura H, Ohono S, Kubota Y
    • Organizer
      Yokohama City University 21st Century COE Program, Cell Polarity 2007-International symposium on CellPolarity Ststem and Future Medicine
    • Place of Presentation
      Hayama
    • Year and Date
      2007-12-09
    • Data Source
      KAKENHI-PROJECT-17014076
  • [Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis.

    • Author(s)
      水島 大一,秋本 和憲,長嶋 洋治,最上 多恵, 佐藤 美紀子,宮城 悦子,亀田 陽一,稲山 嘉明,大橋 健一,青木 一郎,大野 茂男,平原 史樹
    • Organizer
      .第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻.

    • Author(s)
      秋本和憲、長嶋洋治、石黒斉、鄭允文、佐々木和教、谷口英樹、野田哲生、大野茂男
    • Organizer
      第30回日本ヒト細胞学会学術集会
    • Place of Presentation
      梅田スカイビル(大阪府)
    • Data Source
      KAKENHI-PROJECT-23590429
  • [Presentation] A Cell Polarity Protein,aPKCλ,is Essential for Maintaining Hair Follicle Stem Cell Quiescence and Hair Follicle Regeneration

    • Author(s)
      長田真一,峰松直子,小田文乃,秋本和憲,川名誠司,大野茂男
    • Organizer
      第39回日本研究皮膚科学会年次学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-24591669
  • [Presentation] aPKClambda regulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer.

    • Author(s)
      Akimoto K, Nagashima Y, Ishiguro H, Zheng Y W, Osato N, Sasaki K, Kojima Y, Tamura T, Taniguchi H, Noda T, Ohno S
    • Organizer
      US-Japan Summer Conference on Cancer, Diabetes and Inflammation
    • Place of Presentation
      Beckman Center Lecture Hall(Duarte, CA, USA)
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] aPKC λ regulates mammary luminal progenitor cell propagation and it’s disruption in a subpopulation of breast cancer.

    • Author(s)
      Akimoto K, Nagashima Y, Ishiguro H, Zheng Y-W, Sasaki K, Kojima Y, Taniguchi H, Ohno S
    • Organizer
      70th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis.

    • Author(s)
      Mizushima T, Akimoto K, Nagashima Y, Mogami T, Sato M, Miyagi E, Kameda Y, Inayama Y, Ohashi K, Aoki I, Ohno S, Hirahara F
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌、さっぽろ芸術館、札幌市教育文化会館(北海道)
    • Data Source
      KAKENHI-PROJECT-22247030
  • [Presentation] An Apicobasal Cell Polarity Protein aPKCλ regulates the hair follicle cycling and Hair Follicle Stem Cells Homeostasis

    • Author(s)
      Osada S,Minematsu N,Oda F,Akimoto K,Kawana S and Ohno S
    • Organizer
      The 44th Annual European Society for Dermatological Research Meeting
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2014-09-10 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-24591669
  • [Presentation] Prognostic impact of aPKC λ/ι expression in pancreatic cancer.

    • Author(s)
      Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kobayashi N, Maeda S, Ohno S, Nakajima A
    • Organizer
      70th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-22247030
  • 1.  OHNO Shigeo (10142027)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 41 results
  • 2.  NAGASHIMA Yoji (10217995)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 39 results
  • 3.  SUZUKI Atsushi (00264606)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 4 results
  • 4.  HIRAI Syu-ichi (80228759)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 5.  MIZUNO Keiko (90221803)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  ISHIGURO Hitoshi (00381666)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 23 results
  • 7.  UEMURA Hiroji (50244439)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 8.  AOKI Ichiro (00184028)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 9.  HIROSE Tomonori (20381668)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 10.  INAYAMA Yoshiaki (10184730)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 11.  SATO Mikiko (70326049)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 12.  MIZUSHIMA Taichi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 13.  CHISHIMA Takashi (70438141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ISHIKAWA Takashi (80275049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 15.  KANNO Hiroshi (40244496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NOZAWA Akinori (00228321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KUBOTA Yoshinobu (10106312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 18.  KAWASAKI Hiroshi (70169704)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YAMASHITA Akio (20405020)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKAYA Masa-aki (70422095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  SASAKI Kazunori (50438131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 22.  KOIZUMI Toshiyuki (80323575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MITSUDOH Kenji (70303641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  KIOI Mitomu (30545059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OSADA Shin-Ichi (00244484)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 26.  UEMURA Hiroji (70254208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  NAKAIGAWA Noboru (00237207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  OHASHI Ken-ichi (40231203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  MARUYAMA Yasuyo (10534141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  MIYAGI Etsuko (40275053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  HIRAHARA Fumiki (30201734)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  東 恭平 (10463829)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 33.  米野 雅大 (40866307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 34.  TANIGUCHI Tamiyo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 35.  IZUMISAWA Yusuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  KATO Shingo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 37.  IZUMISAWA Yuhsuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  KAWASHIMA Masato
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  杉山 由樹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  ICHIKAWA Yasushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  OKITA Naoyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  高澤 涼子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 43.  來生 知
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  樋上 賀一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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