SAKAI MAKOTO 酒井真

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SAKAI Makoto 酒井真

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Researcher Number	70420099
Other IDs	https://orcid.org/0000-0003-0860-3132
Affiliation (Current)	2024: 群馬大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2019 – 2022: 群馬大学, 医学部附属病院, 講師 2013 – 2018: 群馬大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator アミノ酸トランスポーター / 消化器癌 / がん免疫療法 Except Principal Investigator 食道癌 / 腹膜播種 / 温熱療法 / 免疫チェックポイント阻害剤 / luciferase assay / Hyperthermia / Luciferase assay … More / PD-L1 / HSP110 / スタスミン / PIP / タキサン系薬剤 / PIP化合物 / STMN1 / 微小管ダイナミクス / 放射線感受性 / 放射線抵抗性 / 治療抵抗性 / 放射線 / 酸素ナノバブル / 低酸素 / HDAC阻害剤 / 胃癌 / 腹膜播腫 / 消化器癌 / FBXW7 / 同所移植転移モデル / 同所移植転移モデル微小転移 / 同所移植モデル / 癌 / 微小転移 Less

がん細胞特異的アミノ酸トランスポーターを標的とした新規複合的がん免疫療法の開発Principal Investigator
- Principal Investigator
  
  酒井真
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Gunma University
Development of a innovative combination therapy of hyperthermia and immune checkpoint inhibitors
- Principal Investigator
  
  佐野彰彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Gunma University
Aiming to overcome gastrointestinal cancer by controlling cancer microtubule dynamics using innovative therapeutic tools
- Principal Investigator
  
  Sohda Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Gunma University
Regulation of radiation sensitivity using ultrafine nanobubble oxygen
- Principal Investigator
  
  Yokobori Takehiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Gunma University
Potential of tumore suppressor FBXW7 as one of the therapeutic targets
- Principal Investigator
  
  Yokobori Takehiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Breakthrough of mechanism in micrometastasis using micrometastatic model of esophageal cancer
- Principal Investigator
  
  MIYAZAKI Tatsuya
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University

All 2020 2018 2017 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer2020
- Author(s)
  Baatar Seded、Bai Tuya、Yokobori Takehiko、Gombodorj Navchaa、Nakazawa Nobuhiro、Ubukata Yasunari、Kimura Akiharu、Kogure Norimichi、Sano Akihiko、Sohda Makoto、Sakai Makoto、Tumenjargal Amartuvshin、Ogata Kyoichi、Kuwano Hiroyuki、Shirabe Ken、Saeki Hiroshi
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 27 Issue: 11 Pages: 4360-4368
- DOI
  10.1245/s10434-020-08518-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09219, KAKENHI-PROJECT-18K07665
[Journal Article] CD36 Expression Is Associated with Cancer Aggressiveness and Energy Source in Esophageal Squamous Cell Carcinoma2020
- Author(s)
  Yoshida Tomonori、Yokobori Takehiko、Saito Hideyuki、Kuriyama Kengo、Kumakura Yuji、Honjo Hiroaki、Hara Keigo、Sakai Makoto、Miyazaki Tatsuya、Obinata Hideru、Erkhem-Ochir Bilguun、Gombodorj Navchaa、Sohda Makoto、Saeki Hiroshi、Kuwano Hiroyuki、Shirabe Ken
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 28 Issue: 2 Pages: 1217-1227
- DOI
  10.1245/s10434-020-08711-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07665, KAKENHI-PROJECT-19K09219
[Journal Article] High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab2018
- Author(s)
  Bao H、Bai T、Takata K、Yokobori T、Ohnaga T、Hisada T、Maeno T、Bao P、Yoshida T、Kumakura Y、Honjo H、Sakai M、Sohda M、Fukuchi M、Altan B、Handa T、Ide M、Miyazaki T、Ogata K、Oyama T、Shimizu K、Mogi A、Asao T、Shirabe K、Kuwano H、Kaira K
- Journal Title
  
  Oncology Letters
  
  Volume: 15 Pages: 3061-3067
- DOI
  10.3892/ol.2017.7671
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01432, KAKENHI-PROJECT-15K10085, KAKENHI-PROJECT-17K19893
[Journal Article] Correlation between high FBXW7 expression in pretreatment biopsy specimens and good response to chemoradiation therapy in patients with locally advanced esophageal cancer: A retrospective study2018
- Author(s)
  Navchaa Gombodorj, Takehiko Yokobori, Naritaka Tanaka, Shigemasa Suzuki, Kengo Kuriyama, Yuji Kumakura, Tomonori Yoshida, Makoto Sakai, Makoto Sohda, Seded Baatar, Tatsuya Miyazaki, Masahiko Nishiyama, Ken Shirabe, and Hiroyuki Kuwano
- Journal Title
  
  Journal of Surgical Oncology
  
  Volume: accepted
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10085
[Journal Article] High stathmin 1 expression is associated with poor prognosis and chemoradiation resistance in esophageal squamous cell carcinoma.2017
- Author(s)
  Shigemasa Suzuki, Takehiko Yokobori, Bolag Altan, Keigo Hara, Daigo Ozawa, Naritaka Tanaka, Makoto Sakai, Akihiko Sano, Makoto Sohda, Halin Bao, Minoru Fukuchi, Tatsuya Miyazaki, Kyoichi Kaira, Takayuki Asao, Hiroyuki Kuwano
- Journal Title
  
  International Journal of Oncology
  
  Volume: 印刷中 Issue: 4 Pages: 1184-1190
- DOI
  10.3892/ijo.2017.3899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10085
[Journal Article] Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer.2015
- Author(s)
  Miyazaki T, Sohda M, Tanaka N, Suzuki S, Ieta K, Sakai M, Sano A, Yokobori T, Inose T, Nakajima M, Fukuchi M, Ojima H, Kato H, Kuwano H.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 75 Issue: 3 Pages: 449-55
- DOI
  10.1007/s00280-014-2659-6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Intestinal epithelial culture under an air-liquid interface: a tool for studying human and mouse esophagi.2015
- Author(s)
  Yokobori T, Suzuki S, Miyazaki T, Sohda M, Sakai M, Tanaka N, Ozawa D, Hara K, Honjo H, Altan B, Fukuchi M, Ishii H, Iwatsuki M, Sugimachi K, Sudo T, Iwaya T, Nishida N, Mimori K, Kuwano H, Mori M.
- Journal Title
  
  Dis Esophagus.
  
  Volume: [Epub ahead of print] Issue: 7 Pages: 843-847
- DOI
  10.1111/dote.12346
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22591450, KAKENHI-PROJECT-26461994, KAKENHI-PROJECT-26293303, KAKENHI-PROJECT-15K15496
[Journal Article] Phase II Study of Docetaxel, Nedaplatin, and 5-Fluorouracil Combined Chemotherapy for Advanced Esophageal Cancer.2015
- Author(s)
  Miyazaki T, Ojima H, Fukuchi M, Sakai M, Sohda M, Tanaka N, Suzuki S, Ieta K, Saito K, Sano A, Yokobori T, Inose T, Nakajima M, Kato H, Kuwano H.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: [Epub ahead of print]
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] TGFBI Expression in Cancer Stromal Cells is Associated with Poor Prognosis and Hematogenous Recurrence in Esophageal Squamous Cell Carcinoma.2014
- Author(s)
  Ozawa D, Yokobori T, Sohda M, Sakai M, Hara K, Honjo H, Kato H, Miyazaki T, Kuwano H.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: Epub ahead of print
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] L-[3-18F]-α-methyltyrosine uptake by lymph node metastasis is a predictor of complete response to CRT in esophageal cancer.2014
- Author(s)
  Sohda M, Miyazaki T, Honjyo H, Hara K, Ozawa D, Suzuki S, Tanaka N, Sano A, Sakai M, Yokobori T, Nakajima M, Fukuchi M, Kato H, Higuchi T, Tsushima Y, Kuwano H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 34 Pages: 7473-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] L-[3-18F]-α-methyltyrosine accumulation as a definitive chemoradiotherapy response predictor in patients with esophageal cancer.2014
- Author(s)
  Sohda M, Honjyo H, Hara K, Ozawa D, Suzuki S, Tanaka N, Sano A, Sakai M, Yokobori T, Inose T, Miyazaki T, Ojima H, Higuchi T, Tsushima Y, Kuwano H.
- Journal Title
  
  Anticancer Res
  
  Volume: 34(2) Pages: 909-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Effectiveness of FDG-PET in screening of synchronous cancer of other organs in patients with esophageal cancer.2014
- Author(s)
  Miyazaki T, Sohda M, Higuchi T, Tanaka N, Suzuki S, Sakai M, Yokobori T, Nakajima M, Fukuchi M, Tsushima Y, Kato H, Kuwano H.
- Journal Title
  
  Anticancer Res
  
  Volume: 34(1) Pages: 283-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Use of pre-treatment 18F-FAMT PET to predict patient survival in squamous cell carcinoma of the esophagus treated by curative surgery.2014
- Author(s)
  Sohda M, Sakai M, Honjyo H, Hara K, Ozawa D, Suzuki S, Tanaka N, Yokobori T, Miyazaki T, Fukuchi M, Higuchi T, Tsushima Y, Kuwano H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 34 Pages: 3623-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Re-thoracotomy for intrathoracic complications after esophagectomy for esophageal cancer2013
- Author(s)
  Miyazaki T, Inose T, Tanaka N, Suzuki S, Hara K, Ozawa D, Yokobori T, Sakai M, Souda M, Fukuchi M, Kuwano H.
- Journal Title
  
  Kyobu Geka
  
  Volume: 66(8 Suppl) Pages: 762-6
- NAID
  40019746006
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Clinical significance of total colonoscopy for screening of colon lesions in patients with esophageal cancer.2013
- Author(s)
  Miyazaki T, Tanaka N, Sano A, Suzuki S, Sakai M, Yokobori T, Inose T, Sohda M, Nakajima M, Fukuchi M, Ojima H, Kato H, Kuwano H.
- Journal Title
  
  Anticancer Res
  
  Volume: 33(11) Pages: 5113-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Significance of lymph node capsular invasion in esophageal squamous cell carcinoma.2012
- Author(s)
  Sakai M
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 19 Issue: 6 Pages: 1911-7
- DOI
  10.1245/s10434-012-2232-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Prognostic significance of heat shock protein 110 expression and T lymphocyte infiltration in esophageal cancer2011
- Author(s)
  Nakajima M, Kato H, Miyazaki T, Fukuchi M, Masuda N, Fukai Y, Sohda M, Inose T, Sakai M, Sano A, Tanaka N, Ahmad F, Kuwano H
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 58 Pages: 1555-1560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Journal Article] Ghrelin Level and Body Weight Loss After Esophagectomy for Esophageal Cancer2011
- Author(s)
  Miyazaki T, Tanaka N, Hirai H, Yokobori T, Sano A, Sakai M, Inose T, Sohda M, Nakajima M, Fukuchi M, Kato H, Kuwano H
- Journal Title
  
  J Surg Res.
  
  Volume: (Epub ahead of print) Issue: 1 Pages: 74-78
- DOI
  10.1016/j.jss.2011.09.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591450
[Presentation] A new low-cost and high-quality device for in vivo luciferase assay in peritoneal dissemination mouse model
- Author(s)
  Takehiko Yokobori, Ryo Takahashi, Yuji Kumakura, Hiroaki Honjo, Keigo Hara, Makoto Sakai, Makoto Sohda, Tatsuya Miyazaki, Takayuki Asao, Hiroyuki Kuwano
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-22591450

1. YOKOBORI Takehiko (60420098)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
2. SOHDA Makoto (70507326)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
3. KUWANO Hiroyuki (90186560)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
4. 佐伯浩司 (80325448)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. MIYAZAKI Tatsuya (70372349)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
6. 緒方杏一 (10448897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 田中成岳 (30546726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. 猪瀬崇徳 (90609968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. 堤荘一 (30323356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐野彰彦 (20431702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 矢島俊樹 (20346852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高田耕児

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAI MAKOTO 酒井 真

SAKAI Makoto 酒井 真

Research Projects

Research Products

Co-Researchers

がん細胞特異的アミノ酸トランスポーターを標的とした新規複合的がん免疫療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a innovative combination therapy of hyperthermia and immune checkpoint inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Aiming to overcome gastrointestinal cancer by controlling cancer microtubule dynamics using innovative therapeutic tools

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of radiation sensitivity using ultrafine nanobubble oxygen

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Potential of tumore suppressor FBXW7 as one of the therapeutic targets

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Breakthrough of mechanism in micrometastasis using micrometastatic model of esophageal cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD36 Expression Is Associated with Cancer Aggressiveness and Energy Source in Esophageal Squamous Cell Carcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlation between high FBXW7 expression in pretreatment biopsy specimens and good response to chemoradiation therapy in patients with locally advanced esophageal cancer: A retrospective study2018

Author(s)

Journal Title

Data Source

[Journal Article] High stathmin 1 expression is associated with poor prognosis and chemoradiation resistance in esophageal squamous cell carcinoma.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intestinal epithelial culture under an air-liquid interface: a tool for studying human and mouse esophagi.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase II Study of Docetaxel, Nedaplatin, and 5-Fluorouracil Combined Chemotherapy for Advanced Esophageal Cancer.2015

Author(s)

Journal Title

Data Source

[Journal Article] TGFBI Expression in Cancer Stromal Cells is Associated with Poor Prognosis and Hematogenous Recurrence in Esophageal Squamous Cell Carcinoma.2014

SAKAI MAKOTO 酒井真

SAKAI Makoto 酒井真