Owaki Toshiyuki 大脇敏之

… Alternative Names

大脇敏之オオワキトシユキ

OWAKI Toshiyuki 大脇敏之

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Researcher Number	70453834
Other IDs
Affiliation (Current)	2025: 東京医科大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京医科大学, 医学部, 客員准教授 2019: 九州大学, 先端融合医療創成センター, 特任准教授 2017 – 2018: 東京医科大学, 医学部, 客員准教授 2016 – 2017: 東京女子医科大学, 医学部, 特任講師 2014 – 2015: 東京女子医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Orthopaedic surgery Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medical and hospital managemen
Keywords	Principal Investigator 炎症性腸疾患 / 培養上清 / 歯髄幹細胞 / 移植・再生医療 / 再生医学 / IL-35 / 免疫調節 / IL-27 / 間葉系幹細胞 Except Principal Investigator 肺線維症 … More / プレコンディショニング / IL-27 / 間葉系幹細胞 / 国際情報交換　アメリカ / 成長 / 解離性人格障害 / 意識 / 人格 / 個体 / univariate / 経時性 / 波動 / 音声識別 / 個人同定 / SAS9.4(EG7.1) / nested logistic analysis / ペルソナ / 保健医療連携 / 医療アクセスの為のヘルスアセスメント / Access Assessment(AA) / anticiper de ja saisir / nested logistic分析 / voice approach / odds比の負の寄与 / access assessment / 多重人格 / 人格識別 / 解離性同一性障害 Less

Development of a new treatment method for repairing intestinal epithelial function of inflammatory bowel disease by human pulp MSC-conditioned mediumPrincipal Investigator
- Principal Investigator
  
  大脇敏之
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical University
Inhibition of pulmonary fibrosis by mesenchymal stem cells through IL-27 and its clinical application
- Principal Investigator
  
  田口紋子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Medical University
Therapeutic effect of mesenchymal stem cells by anti-inflammatory cytokinesIL-27 and IL-35Principal Investigator
- Principal Investigator
  
  OWAKI Toshiyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University
  Tokyo Medical University
Study of possibility of discrimination of personae using biological censors
- Principal Investigator
  
  SAWAGUCHI TOSHIKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical and hospital managemen
- Research Institution
  National Institute of Public Health
  Teikyo Heisei University

All 2023 2022 2018 2017 2015

All Journal Article Presentation

[Journal Article] Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP-4.2023
- Author(s)
  Furusaka Y, Inoue S, Mizoguchi I, Hasegawa H, Katahira Y, Watanabe A, Sakamoto E, Sekine A, Miyakawa S, Umezu T, Owaki T, Yoneto T, Yoshimoto T.
- Journal Title
  
  Cancer Sci.
  
  Volume: in press Issue: 6 Pages: 2499-2514
- DOI
  10.1111/cas.15789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K08018, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K08722, KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-21K09779, KAKENHI-PROJECT-21K12256
[Journal Article] Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases.2018
- Author(s)
  Chiba Y, Mizoguchi I, Hasegawa H, Ohashi M, Orii N, Nagai T, Sugahara M, Miyamoto Y, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Cell. Mol. Life Sci.
  
  Volume: 75 Issue: 8 Pages: 1363-1376
- DOI
  10.1007/s00018-017-2724-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Interleukin-27 exerts its antitumor effects by promoting differentiation of hematopoietic stem cells to M1 macrophages.2018
- Author(s)
  Chiba Y, Mizoguchi I, Furusawa J, Hasegawa H, Ohashi M, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Issue: 1 Pages: 182-194
- DOI
  10.1158/0008-5472.can-17-0960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Protective effects against tumors and infection by IL-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors.2018
- Author(s)
  Orii N, Mizoguchi I, Chiba Y, Hasegawa H, Ohashi M, Xu M, Nagai T, Ochiai M, Mochizuki Y, Owaki T, Yoshimoto T.
- Journal Title
  
  Oncoimmunology
  
  Volume: - Issue: 5 Pages: e1421892-e1421892
- DOI
  10.1080/2162402x.2017.1421892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017
- Author(s)
  Mizoguchi I, Ohashi M, Chiba Y, Hasegawa H, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Front. Immunol.
  
  Volume: 8 Pages: 929-929
- DOI
  10.3389/fimmu.2017.00929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] 個人同定に関わる四つの今日的試み2015
- Author(s)
  澤口聡子、京相雅樹、加茂登志子、坂本慎一、李孝珍、中島章博、滝口清昭、河野賢司、米山万里枝、大脇敏之
- Journal Title
  
  学習院女子大学紀要
  
  Volume: 17 Pages: 71-78
- NAID
  120005579005
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670351
[Presentation] Protective effect of conditioned medium of immortalized stem cells from human exfoliated deciduous tooth on the peripheral neuropathy of experimental autoimmune neuritis.2022
- Author(s)
  Hasegawa H, Sakamoto E, Katahira Y, Miyakawa S, Murakami F, Inoue S, Watanabe A, Furusaka Y, SekineA, Owaki T, Mizoguchi I, Yoshimoto T.
- Organizer
  JSICR/MMCB 2022 Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08018
[Presentation] ヒト間葉系幹細胞による免疫調節とIL-27の関係性2018
- Author(s)
  大脇敏之、菅原京加、落合央、溝口出、千葉佑規乃、長谷川英哲、折井直子、宮本泰則、弓場俊輔、善本隆之
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] ヒト臍帯血由来間葉系幹細胞による免疫調節とIL-27の関係性2018
- Author(s)
  大脇敏之、溝口出、杉山大介、善本隆之
- Organizer
  第83回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] ヒト間葉系幹細胞によるIL-27の関与2018
- Author(s)
  大脇敏之、溝口出、長谷川英哲、折井直子、善本隆之
- Organizer
  第181回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] IL-27/IL-35共通サブユニットEBI3によるIL-23Rの新しい蛋白質発現安定化機構2017
- Author(s)
  溝口出、千葉祐規乃、長谷川英哲、大橋美緒、中村涼乃、折井直子、干詩宇、徐明利、大脇敏之、善本隆之
- Organizer
  第6回医薬工3大学包括連携推進シンポジウム
- Data Source
  KAKENHI-PROJECT-17K11030

1. 善本隆之 (80202406)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. 加茂登志子 (20186018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. SAWAGUCHI TOSHIKO (90235458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 米山万里枝 (00554247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 滝口清昭 (30539002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 坂本慎一 (80282599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 多木崇 (70408475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 栗原千絵子 (40620761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 加藤則子 (30150171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐藤啓造 (20162422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 京相雅樹 (20277825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 平澤恭子 (50316709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 杉山登志朗 (60216348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 森友久 (40366331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田口紋子 (60581501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 溝口出 (00569527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
17. 宮川聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Owaki Toshiyuki 大脇 敏之

大脇 敏之 オオワキ トシユキ

OWAKI Toshiyuki 大脇 敏之

Research Projects

Research Products

Co-Researchers

Development of a new treatment method for repairing intestinal epithelial function of inflammatory bowel disease by human pulp MSC-conditioned mediumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inhibition of pulmonary fibrosis by mesenchymal stem cells through IL-27 and its clinical application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic effect of mesenchymal stem cells by anti-inflammatory cytokinesIL-27 and IL-35Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of possibility of discrimination of personae using biological censors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP-4.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin-27 exerts its antitumor effects by promoting differentiation of hematopoietic stem cells to M1 macrophages.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective effects against tumors and infection by IL-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 個人同定に関わる四つの今日的試み2015

Author(s)

Journal Title

NAID

Data Source

[Presentation] Protective effect of conditioned medium of immortalized stem cells from human exfoliated deciduous tooth on the peripheral neuropathy of experimental autoimmune neuritis.2022

Author(s)

Organizer

Data Source

[Presentation] ヒト間葉系幹細胞による免疫調節とIL-27の関係性2018

Author(s)

Organizer

Data Source

[Presentation] ヒト臍帯血由来間葉系幹細胞による免疫調節とIL-27の関係性2018

Author(s)

Organizer

Data Source

[Presentation] ヒト間葉系幹細胞によるIL-27の関与2018

Author(s)

Organizer

Data Source

[Presentation] IL-27/IL-35共通サブユニットEBI3によるIL-23Rの新しい蛋白質発現安定化機構2017

Author(s)

Organizer

Data Source

Owaki Toshiyuki 大脇敏之

大脇敏之オオワキトシユキ

OWAKI Toshiyuki 大脇敏之