NARUSE Tomofumi 鳴瀬智史

Researcher Number	70549609
Other IDs
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(歯学系), 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 長崎大学, 病院(歯学系), 講師 2021: 長崎大学, 病院(歯学系), 助教 2019: 長崎大学, 医歯薬学総合研究科(歯学系), 客員研究員 2015 – 2018: 長崎大学, 医歯薬学総合研究科(歯学系), 助教 2011 – 2012: 長崎大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 口腔癌 / PIK3CA遺伝子 / 口腔扁平上皮癌 / EGFR / セツキシマブ耐性 / PI3Kp110α / セツキシマブ / mTOR阻害薬 / PD-L1 / 腫瘍微小環境 … More / ミスマッチ遺伝子 / ペムブロリズマブ / 上皮間葉転換 / PIK3CA / 耐性 / アルペリシブ / Resistance / mTOR / 分子標的治療薬 / 低酸素領域 / 低酸素 / 癌幹細胞 / リンパ節転移 / 臨床腫瘍学 … More Except Principal Investigator 免疫学的解析 / 被膜外浸潤 / 頸部リンパ節転移 / 口腔癌 Less

Immunological investigation of extracapsular spread mechanism of oral squamous cell carcinoma cervical lymph node metastasis
- Principal Investigator
  
  山田慎一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Toyama
ペムブロリズマブの治療効果予測に関する薬剤感受性機構の解明Principal Investigator
- Principal Investigator
  
  鳴瀬智史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Elucidation of drug sensitivity control mechanism to enhance the therapeutic effect of cetuximab on oral cancerPrincipal Investigator
- Principal Investigator
  
  NARUSE Tomofumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Fundamental study on molecular target therapy in oral cancer patients with cetuximab resistancePrincipal Investigator
- Principal Investigator
  
  NARUSE Tomofumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Fundamental study about the cancer-of-the-mouth stem cell andmolecular target drug under low oxygen environmentPrincipal Investigator
- Principal Investigator
  
  NARUSE Tomofumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University

All 2022 2019 2016 2015 2012

All Journal Article Presentation

[Journal Article] Clinicopathological study of primary intraosseous squamous cell carcinoma of the jaw and a review of the literature2016
- Author(s)
  Tomofumi Naruse
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery
  
  Volume: 00 印刷中
- NAID
  120006987582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20544
[Journal Article] 生検では癌腫が認められなかった多形腺腫由来癌の1例2016
- Author(s)
  鳴瀬　智史
- Journal Title
  
  日本口腔診断学会雑誌
  
  Volume: 00　印刷中
- NAID
  130005421120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20544
[Journal Article] Cetuximab for the treatment of locally advanced and recurrent/metastatic oral cancer: An investigation of distant metastasis2016
- Author(s)
  Tomofumi Naruse
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 00 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20544
[Journal Article] Histopathological and immunohistochemical study of keratocystic odontogenic tumors: correlation with recurrence2016
- Author(s)
  Tomofumi Naruse
- Journal Title
  
  Oncology letters
  
  Volume: 00　印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20544
[Journal Article] Acute septic arthritis of the temporomandibular joint: a case report2016
- Author(s)
  Tomofumi Naruse
- Journal Title
  
  日本口腔診断学会雑誌
  
  Volume: 00　印刷中
- NAID
  130005432624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20544
[Presentation] 当科における再発・転移口腔癌に対しPembrolizumabを用いた症例2022
- Author(s)
  三好太郎、鳴瀬智史、大鶴光信、梅田正博
- Organizer
  日本口腔腫瘍学会
- Data Source
  KAKENHI-PROJECT-21K10117
[Presentation] 再発/転移口腔癌に対するセツキシマブの治療効果を高めるための薬剤感受性機構の検討2019
- Author(s)
  土橋宏輝、鳴瀬智史、柳本惣市、大森景介、古川浩平、梅田正博
- Organizer
  日本口腔外科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K17267
[Presentation] 口腔癌におけるPIK3CAの発現とセツキシマブ療法の治療効果に関する検討2016
- Author(s)
  鳴瀬　智史
- Organizer
  第70回日本口腔科学会総会・学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15K20544
[Presentation] 口腔扁平上皮癌におけるmTORC2の発現と分子標的薬併用による抗腫瘍効果について2015
- Author(s)
  鳴瀬　智史
- Organizer
  第60回日本口腔外科学会総会・学術大会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K20544
[Presentation] 進行・再発口腔癌におけるセツキシマブ投与による遠隔転移巣の制御に関する検討2015
- Author(s)
  鳴瀬　智史
- Organizer
  第53回日本癌治療学会学術集会
- Place of Presentation
  京都国際会議場（京都府・京都市）
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-15K20544
[Presentation] 当科で経験した顎骨中心性扁平上皮癌の臨床的検討2015
- Author(s)
  鳴瀬智史
- Organizer
  第39回日本頭頸部癌学会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-15K20544
[Presentation] mTOR阻害薬everolimusの口腔扁平上皮癌細胞株に対する抗腫瘍効果について2012
- Author(s)
  鳴瀬　智史
- Organizer
  第57回日本口腔外科学会総会・学術集会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23659950

1. 柳本惣市 (10315260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 山田慎一 (50380853)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 奥山紘平 (30781968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山川延宏 (00526709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 栗田浩 (10273103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 長谷川巧実 (50546497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 桐田忠昭 (70201465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NARUSE Tomofumi 鳴瀬 智史

Research Projects

Research Products

Co-Researchers

Immunological investigation of extracapsular spread mechanism of oral squamous cell carcinoma cervical lymph node metastasis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ペムブロリズマブの治療効果予測に関する薬剤感受性機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of drug sensitivity control mechanism to enhance the therapeutic effect of cetuximab on oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fundamental study on molecular target therapy in oral cancer patients with cetuximab resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fundamental study about the cancer-of-the-mouth stem cell andmolecular target drug under low oxygen environmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Clinicopathological study of primary intraosseous squamous cell carcinoma of the jaw and a review of the literature2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 生検では癌腫が認められなかった多形腺腫由来癌の1例2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cetuximab for the treatment of locally advanced and recurrent/metastatic oral cancer: An investigation of distant metastasis2016

Author(s)

Journal Title

Data Source

[Journal Article] Histopathological and immunohistochemical study of keratocystic odontogenic tumors: correlation with recurrence2016

Author(s)

Journal Title

Data Source

[Journal Article] Acute septic arthritis of the temporomandibular joint: a case report2016

Author(s)

Journal Title

NAID

Data Source

[Presentation] 当科における再発・転移口腔癌に対しPembrolizumabを用いた症例2022

Author(s)

Organizer

Data Source

[Presentation] 再発/転移口腔癌に対するセツキシマブの治療効果を高めるための薬剤感受性機構の検討2019

Author(s)

Organizer

Data Source

[Presentation] 口腔癌におけるPIK3CAの発現とセツキシマブ療法の治療効果に関する検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 口腔扁平上皮癌におけるmTORC2の発現と分子標的薬併用による抗腫瘍効果について2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 進行・再発口腔癌におけるセツキシマブ投与による遠隔転移巣の制御に関する検討2015

Author(s)

Organizer

NARUSE Tomofumi 鳴瀬智史