HAYASHI TAKUO 林大久生

… Alternative Names

Hayashi Takuo 林大久生

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Researcher Number	70569128
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 順天堂大学, 医学部, 准教授 2014: 順天堂大学, 医学部, 助教 2013: 順天堂大学, 医学部, 非常勤助教 2012: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49020:Human pathology-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 53010:Gastroenterology-related / Basic Section 56020:Orthopedics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 肺癌 / 個別化医療 / エンハンサー / トランスクリプトーム解析 / CAGE / 遺伝子 / 肺がん / トランスクリプトーム / がん / 多領域シークエンス … More / バイオマーカー / 免疫療法 / PD-L1 / PD-1 / 多領域シーケンス / 免疫治療 / トランスレーショナルリサーチ / 病理学 / 肺腺癌 / 人体病理 / HIF-1α / VEGF-D / mTORシグナル伝達系 / 低酸素誘導因子 / リンパ管内皮細胞増殖因子 / TSC遺伝子 / リンパ脈管筋腫症 … More Except Principal Investigator 胃癌 / 骨軟部肉腫 / 免疫応答 / 骨軟部腫瘍 / 免疫チェックポイント阻害薬 / 予測 / 効果予測 / 機械学習 / 肺癌 / スプライシング / 酸化ストレス経路 / 抗癌剤耐性 / 非小細胞肺癌 / Keap1-Nrf2経路 / 酸化ストレス応答経路 / 小細胞肺癌 / 多領域シークエンス / 次世代シーケンサー / GA-FGM / GA-FG / Oxyntic gland adenoma / ピロリ未感染胃癌 / 胃底腺粘膜型腺癌 / 胃底腺型腺癌 / 胃底腺型胃癌 / チロシンキナーゼ阻害剤 / プレシジョンメディシン / チロシンキナーゼ / 融合遺伝子 / がんクリニカルシークエンス / 微小環境 / 小胞体ストレス Less

網羅的遺伝子発現解析技術を用いたH.pylori未感染胃癌の発癌機構の解明
- Principal Investigator
  
  上山浩也
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Developing a model to predict response to immune checkpoint inhibitor using machine learning
- Principal Investigator
  
  宿谷威仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
Development of personalized medicine for lung cancer using next-generation transcriptomePrincipal Investigator
- Principal Investigator
  
  林大久生
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Juntendo University
Carcinogenesis of gastric adenocarcinoma of fundic-gland type
- Principal Investigator
  
  Ueyama Hiroya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
小細胞肺癌における酸化ストレス応答系の破綻機序の解明
- Principal Investigator
  
  光石陽一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
Elucidation of the molecular mechanism of immunotherapy treatment resistance by microtissue multidisciplinary sequencePrincipal Investigator
- Principal Investigator
  
  Takuo Hayashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Juntendo University
Development of novel treatment based on functional analysis of endoplasmic reticulum stress in bone and soft tissue sarcoma
- Principal Investigator
  
  Suehara Yoshiyuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  National Cancer Center Japan
  Juntendo University
Functional analysis and discovery of molecular targets in bone and soft tissue sarcoma based on cancer clinical sequence
- Principal Investigator
  
  Suehara Yoshiyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Functional analysis of lung cancers with RASA1 mutationsPrincipal Investigator
- Principal Investigator
  
  Hayashi Takuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Juntendo University
リンパ脈管筋腫症におけるリンパ管内皮のプロスタグランジン発現と病態進展への関与Principal Investigator
- Principal Investigator
  
  林大久生
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Juntendo University
Do LAM cells express VEGF-D through the activation of mTORC1/ HIF-1a/ VEGF pathway?Principal Investigator
- Principal Investigator
  
  HAYASHI TAKUO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2014 2013 2012 Other

All Journal Article Presentation Book Other

[Book] PrecisionMedicine　特集「がんゲノム医療の基礎と臨床」各論病理診断医の立場から見たがんクリニカルシークエンス検査 -MSK-IMPACT日本導入の経験から-2019
- Author(s)
  林大久生
- Total Pages
  102
- Publisher
  北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-16K08674
[Book] 呼吸(0286-9314)31巻9号【最近10年で最も進歩した研究分野を検証する】リンパ脈管筋腫症(LAM)2012
- Author(s)
  林大久生,瀬山邦明
- Data Source
  KAKENHI-PROJECT-24790363
[Journal Article] NTRK2 expression in gastrointestinal stromal tumors with a special emphasis on the clinicopathological and prognostic impacts2024
- Author(s)
  Sasa Keita,Son Raku,Oguchi Akiko,Ashizawa Karin,Hasegawa Nobuhiko,Kubota Daisuke,Suehara Yoshiyuki,Takagi Tatsuya,Okubo Taketo,Akaike Keisuke,Sugimoto Kiichi,Takahashi Makoto,Sakamoto Kazuhiro,Hashimoto Takashi,Mine Shinji,Fukunaga Tetsu,Ishijima Muneaki,Hayashi Takuo,Yao Takashi,Murakawa Yasuhiro,Saito Tsuyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 768-768
- DOI
  10.1038/s41598-024-51211-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KF0209, KAKENHI-PROJECT-20K07415, KAKENHI-PROJECT-19K22694
[Journal Article] Endoplasmic Reticulum Stress in Osteosarcoma: IRE1α-XBP1 Inhibition Exerts Anti-Tumor Activity.2023
- Author(s)
  Sasa K, Saito T, Kurihara T, Hasegawa N, Sano K, Kubota D, Akaike K, Okubo T, Hayashi T, Takagi T, Yao T, Ishijima M, Suehara Y.
- Journal Title
  
  J Oncol Res Ther
  
  Volume: 7 Issue: 4 Pages: 10157-10157
- DOI
  10.29011/2574-710x.10157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22963, KAKENHI-PROJECT-19H03789
[Journal Article] Expression of paired box 9 defines an aggressive subset of lung adenocarcinoma preferentially occurring in smokers2023
- Author(s)
  Hayashi Takuo、Kishi Monami、Takamochi Kazuya、Hosoya Masaki、Kohsaka Shinji、Kishikawa Satsuki、Ura Ayako、Sano Kei、Sasahara Noriko、Suehara Yoshiyuki、Takahashi Fumiyuki、Saito Tsuyoshi、Suzuki Kenji、Yao Takashi、the Tokyo Metropolitan Innovative Oncology Research Group (TMIG)
- Journal Title
  
  Histopathology
  
  Volume: 82 Issue: 5 Pages: 672-683
- DOI
  10.1111/his.14853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-22K15416, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-21H02795
[Journal Article] Early Detection of Therapeutic Benefit from PD-1/PD-L1 Blockade in Advanced Lung Cancer by Monitoring Cachexia-Related Circulating Cytokines2023
- Author(s)
  Xu Shiting、Miura Keita、Shukuya Takehito、Harada Sonoko、Fujioka Masahiro、Winardi Wira、Shimamura Shoko、Kurokawa Kana、Sumiyoshi Issei、Miyawaki Taichi、Asao Tetsuhiko、Mitsuishi Yoichiro、Tajima Ken、Takahashi Fumiyuki、Hayashi Takuo、Harada Norihiro、Takahashi Kazuhisa
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 4 Pages: 1170-1170
- DOI
  10.3390/cancers15041170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-19K23978, KAKENHI-PROJECT-21K08187
[Journal Article] CALML5 is a novel diagnostic marker for differentiating thymic squamous cell carcinoma from type B3 thymoma.2023
- Author(s)
  Kanamori K, Suina K, Shukuya T, Takahashi F, Hayashi T, Hara K, Saito T, Mitsuishi Y, Shimamura SS, Winardi W, Tajima K, Ko R, Mimori T, Asao T, Itoh M, Kawaji H, Suehara Y, Takamochi K, Suzuki K, Takahashi K.
- Journal Title
  
  Thoracic Cancer
  
  Volume: 14 Issue: 12 Pages: 1089-1097
- DOI
  10.1111/1759-7714.14853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Clinicopathological and molecular characterization of early gastric adenocarcinoma in Helicobacter pylori-uninfected patients: emphasis on differentiated gastric adenocarcinoma.2022
- Author(s)
  Akazawa Y, Ueyama H, Hayashi T, Utsunomiya H, Uchida R, Abe D, Oki S, Suzuki N, Ikeda A, Yatagai N, Komori H, Takeda T, Matsumoto K, Ueda K, Matsumoto K, Asaoka D, Hojo M, Saito T, Yao T, Nagahara A.
- Journal Title
  
  J Gastroenterol
  
  Volume: 57(10) Issue: 10 Pages: 725-734
- DOI
  10.1007/s00535-022-01906-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08393
[Journal Article] Clinical relevance of PD-L2 expression in surgically resected lung adenocarcinoma.2022
- Author(s)
  Takamochi K, Hara K, Hayashi T, Kohsaka S, Takahashi F, Suehara Y, Shimokawa M, Suzuki K.
- Journal Title
  
  Lung Cancer
  
  Volume: 168 Pages: 50-58
- DOI
  10.1016/j.lungcan.2022.04.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19H03789
[Journal Article] Establishment of Rapid and Accurate Screening System for Molecular Target Therapy of Osteosarcoma2022
- Author(s)
  Sasa Keita、Saito Tsuyoshi、Kurihara Taisei、Hasegawa Nobuhiko、Sano Kei、Kubota Daisuke、Akaike Keisuke、Okubo Taketo、Hayashi Takuo、Takagi Tatsuya、Ishijima Muneaki、Suehara Yoshiyuki
- Journal Title
  
  Technology in Cancer Research & Treatment
  
  Volume: 21 Pages: 15-15
- DOI
  10.1177/15330338221138217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Molecular and clinicopathological analysis revealed an immuno-checkpoint inhibitor as a potential therapeutic target in a subset of high-grade myxofibrosarcoma2022
- Author(s)
  Yamashita Atsushi、Suehara Yoshiyuki、Hayashi Takuo、Takagi Tatsuya、Kubota Daisuke、Sasa Keita、Hasegawa Nobuhiko、Ishijima Muneaki、Yao Takashi、Saito Tsuyoshi
- Journal Title
  
  Virchows Archiv
  
  Volume: 481 Issue: 4 Pages: 1-17
- DOI
  10.1007/s00428-022-03358-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Distinct properties of pure- and mixed-type high-grade fetal lung adenocarcinomas by genetic profiling and transcription factor expression.2022
- Author(s)
  Kishikawa S, Hayashi T, Saito T, Takamochi K, Sasa K, Suehara Y, Takahashi F, Sasahara N, Kohsaka S, Suzuki K, Yao T
- Journal Title
  
  Virchows Arch
  
  Volume: 480 Issue: 3 Pages: 609-619
- DOI
  10.1007/s00428-021-03247-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187
[Journal Article] Transcription start site-level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance.2021
- Author(s)
  Sano K, Hayashi T, Suehara Y, Hosoya M, Takamochi K, Kohsaka S, Kishikawa S, Kishi M, Saito S, Takahashi F, Kaneko K, Suzuki K, Yao T, Ishijima M, Saito T.
- Journal Title
  
  J Pathol Clin Res
  
  Volume: 7 Issue: 4 Pages: 361-374
- DOI
  10.1002/cjp2.213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Correction to: A case of primary distal-type epithelioid sarcoma of the lumbar vertebra with a review of literature2021
- Author(s)
  Ura Ayako、Saito Tsuyoshi、Motoi Toru、Takagi Tatsuya、Suehara Yoshiyuki、Kurihara Taisei、Sano Kei、Sasa Keita、Hayashi Takuo、Yao Takashi
- Journal Title
  
  Virchows Archiv
  
  Volume: 478 Issue: 3 Pages: 613-613
- DOI
  10.1007/s00428-020-02970-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] NTRK fusion in Japanese colorectal adenocarcinomas2021
- Author(s)
  Yamashiro Y.、Kurihara T.、Hayashi T.、Suehara Y.、Yao T.、Kato S.、Saito T.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5635-5635
- DOI
  10.1038/s41598-021-85075-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07740, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Histological characteristics of lung adenocarcinoma with uncommon actionable alterations: special emphasis on MET exon 14 skipping alterations2021
- Author(s)
  Hayashi Takuo、Kohsaka Shinji、Takamochi Kazuya、Kishikawa Satsuki、Ikarashi Daiki、Sano Kei、Hara Kieko、Onagi Hiroko、Suehara Yoshiyuki、Takahashi Fumiyuki、Saito Tsuyoshi、Nakatsura Tetsuya、Kitano Shigehisa、Suzuki Kenji、Yao Takashi
- Journal Title
  
  Histopathology
  
  Volume: - Issue: 7 Pages: 1-1
- DOI
  10.1111/his.14311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19K07469, KAKENHI-PROJECT-19H03789
[Journal Article] Nodular fasciitis adjacent to the left humerus in a 15-year-old boy2021
- Author(s)
  Sasa Keita、Suehara Yoshiyuki、Takagi Tatsuya、Sano Kei、Hayashi Takuo、Saito Tsuyoshi
- Journal Title
  
  Human Pathology: Case Reports
  
  Volume: 23 Pages: 200478-200478
- DOI
  10.1016/j.ehpc.2021.200478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.2021
- Author(s)
  Hasegawa N, Kohsaka S, Kurokawa K, Shinno Y, Takeda Nakamura I, Ueno T, Kojima S, Kawazu M, Suehara Y, Ishijima M, Goto Y, Kojima Y, Yonemori K, Hayashi T, Saito T, Shukuya T, Takahashi F, Takahashi K, Mano H.
- Journal Title
  
  Cancer Sci
  
  Volume: 112 Issue: 10 Pages: 4393-4403
- DOI
  10.1111/cas.15084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-21K08187, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-21K20846, KAKENHI-PROJECT-19H03789
[Journal Article] Establishment of a patient-derived xenograft mouse model of pleomorphic leiomyosarcoma2021
- Author(s)
  Shimada Yasuhiro、Naito Tomoharu、Hayashi Takuo、Saito Tsuyoshi、Suehara Yoshiyuki、Kakinuma Chihaya、Nozaki Yuji、Takagi Hisayoshi、Yao Takashi
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 34 Issue: 1 Pages: 89-93
- DOI
  10.1293/tox.2020-0061
- NAID
  130007982485
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Programmed death-ligand 1 expression and its associations with clinicopathological features, prognosis, and driver oncogene alterations in surgically resected lung adenocarcinoma2021
- Author(s)
  Takamochi K, Hara K, Hayashi T, Kohsaka S, Takahashi F, Suehara Y, Suzuki K.
- Journal Title
  
  Lung Cancer
  
  Volume: 161 Pages: 163-170
- DOI
  10.1016/j.lungcan.2021.09.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02795, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Diffuse expression of MUC6 defines a distinct clinicopathological subset of pulmonary invasive mucinous adenocarcinoma2020
- Author(s)
  Kishikawa S, Hayashi T, Saito T, Takamochi K, Kohsaka S, Sano K, Sasahara N, Sasa K, Kurihara T, Hara K, Suehara Y, Takahashi F, Suzuki K, Yao T
- Journal Title
  
  Mod Pathol
  
  Volume: － Issue: 4 Pages: 786-797
- DOI
  10.1038/s41379-020-00690-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma2020
- Author(s)
  Suehara Y, Kohsaka S, Hayashi T, Akaike K, Kurisaki-Arakawa A, Sato S, Kobayashi E, Mizuno S, Ueno T, Morii T, Okuma T, Kurihara T, Hasegawa N, Sano K, Sasa K, Okubo T, Kim Y, Mano H, Saito T
- Journal Title
  
  Clin Orthop Relat Res
  
  Volume: － Issue: 4 Pages: 838-852
- DOI
  10.1097/corr.0000000000001548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03777, KAKENHI-PROJECT-19K22680, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-20K07415, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation2020
- Author(s)
  Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H, Takahashi K
- Journal Title
  
  Thorac Cancer
  
  Volume: 11 Issue: 1 Pages: 140-149
- DOI
  10.1111/1759-7714.13255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K09669
[Journal Article] 骨・軟部腫瘍のゲノム医療とカウンセリング　軟部肉腫の新規MAN1A1-ROS1融合遺伝子の同定2020
- Author(s)
  末原義之, 高阪真路, 林大久生, 佐藤信吾, 小林英介, 金子和夫, 加藤俊介, Ladanyi Marc, 齋藤剛
- Journal Title
  
  日本整形外科学会雑誌
  
  Volume: 94 Pages: 832-840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03789
[Journal Article] Preoperative denosumab treatment with curettage may be a risk factor for recurrence of giant cell tumor of bone2020
- Author(s)
  Sano Kei、Suehara Yoshiyuki、Okubo Taketo、Sasa Keita、Kurihara Taisei、Akaike Keisuke、Kubota Daisuke、Torigoe Tomoaki、Hasegawa Nobuhiko、Ishii Midori、Nakamura Yasuhiro、Kim Youngji、Takagi Tatsuya、Kaneko Kazuo、Hayashi Takuo、Saito Tsuyoshi
- Journal Title
  
  Journal of Orthopaedic Surgery
  
  Volume: 28 Issue: 2 Pages: 1-1
- DOI
  10.1177/2309499020929786
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Nanostring-based screening for tyrosine kinase fusions in inflammatory myofibroblastic tumors2020
- Author(s)
  Kurihara Taisei、Suehara Yoshiyuki、Akaike Keisuke、Hayashi Takuo、Kohsaka Shinji、Ueno Toshihide、Hasegawa Nobuhiko、Takagi Tatsuya、Sasa Keita、Okubo Taketo、Kim Youngji、Mano Hiroyuki、Yao Takashi、Kaneko Kazuo、Saito Tsuyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41598-020-75596-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789
[Journal Article] Clinicopathological characteristics of lung adenocarcinoma with compound EGFR mutations.2020
- Author(s)
  Hayashi T, Kohsaka S, Takamochi K, Hara K, Kishikawa S, Sano K, Takahashi F, Suehara Y, Saito T, Takahashi K, Suzuki K, Yao T.
- Journal Title
  
  Human Pathology
  
  Volume: 14 Pages: 42-51
- DOI
  10.1016/j.humpath.2020.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-19K07469
[Journal Article] Molecular and clinicopathological features of colorectal adenocarcinoma with enteroblastic differentiation.2020
- Author(s)
  3.Yamashiro Y, Saito T, Hayashi T, Murakami T, Yanai Y, Tsuyama S, Suehara Y, Takamochi K, Yao T.
- Journal Title
  
  Histopathol
  
  Volume: in press Issue: 3 Pages: 492-502
- DOI
  10.1111/his.14158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08704, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Nintedanib inhibits epithelial-mesenchymal transition in A549 alveolar epithelial cells through regulation of the TGF-β/Smad pathway2020
- Author(s)
  Ihara Hiroaki、Mitsuishi Yoichiro、Kato Motoyasu、Takahashi Fumiyuki、Tajima Ken、Hayashi Takuo、Takamochi Kazuya、Suehara Yoshiyuki、Ogura Dai、Niwa Shin-ichiro、Suzuki Kenji、Takahashi Kazuhisa
- Journal Title
  
  Respiratory Investigation
  
  Volume: 58 Issue: 4 Pages: 275-284
- DOI
  10.1016/j.resinv.2020.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Transformation from EGFR/PTEN co-mutated lung adenocarcinoma to small cell carcinoma in lymph node metastasis2020
- Author(s)
  Hayashi T, Takamochi K, Kohsaka S, Kishikawa S, Suehara Y, Takahashi F, Suzuki K, Saito T, Yao T
- Journal Title
  
  Pathology International
  
  Volume: － Issue: 5 Pages: 295-299
- DOI
  10.1111/pin.12919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789
[Journal Article] Comprehensive clinicopathological and molecular analysis of primary malignant melanoma of the oesophagus2020
- Author(s)
  Tsuyama Sho、Kohsaka Shinji、Hayashi Takuo、Suehara Yoshiyuki、Hashimoto Takashi、Kajiyama Yoshiaki、Tsurumaru Masahiko、Ueno Toshihide、Mano Hiroyuki、Yao Takashi、Saito Tsuyoshi
- Journal Title
  
  Histopathology
  
  Volume: 78 Issue: 2 Pages: 240-251
- DOI
  10.1111/his.14210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789
[Journal Article] A case of primary distal-type epithelioid sarcoma of the lumbar vertebra with a review of literature2020
- Author(s)
  Ura Ayako、Saito Tsuyoshi、Motoi Toru、Takagi Tatsuya、Suehara Yoshiyuki、Kurihara Taisei、Sano Kei、Sasa Keita、Hayashi Takuo、Yao Takashi
- Journal Title
  
  Virchows Archiv
  
  Volume: - Issue: 2 Pages: 1-1
- DOI
  10.1007/s00428-020-02955-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-20K07415
[Journal Article] Assessment of Predictive Biomarkers of the Response to Pazopanib Based on an Integrative Analysis of High-grade Soft-tissue Sarcomas: Analysis of a Tumor Sample from a Responder and Patients with Other Soft-tissue Sarcomas2020
- Author(s)
  Suehara Y.、Kohsaka S.、Yamaguchi S.、Hayashi T.、Kurihara T.、Sano K.、Sasa K.、Akaike K.、Ueno T.、Kojima S.、Ikegami M.、Mizuno S.、Okubo T.、Kim Y.、Kaneko K.、Saito T.、Kato S.、Mano H.
- Journal Title
  
  Clinical Orthopaedics & Related Research
  
  Volume: 478 Issue: 11 Pages: 2461-2476
- DOI
  10.1097/corr.0000000000001322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07740, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789
[Journal Article] Identification of Novel CD74-NRG2α Fusion From Comprehensive Profiling of Lung Adenocarcinoma in Japanese Never or Light Smokers2020
- Author(s)
  Kohsaka S, Hayashi T, Nagano M, Ueno T, Kojima S, Kawazu M, Shiraishi Y, Kishikawa S, Suehara Y, Takahashi F, Takahashi K, Suzuki K, Takamochi K, Mano H
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: － Issue: 6 Pages: 30098-8
- DOI
  10.1016/j.jtho.2020.01.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K08185, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-17K09669
[Journal Article] Clinical genomic sequencing of pediatric and adult osteosarcoma reveals distinct molecular subsets with potentially targetable alterations.2019
- Author(s)
  Suehara Y, Alex D, Bowman A, Middha S, Zehir A, Chakravarty D, Wang L, Jour G, Nafa K, Hayashi T, Jungbluth AA, Frosina D, Slotkin E, Shukla N, Meyers P, Healey J, Hameed M, Ladanyi M.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 25 Issue: 21 Pages: 6346-6356
- DOI
  10.1158/1078-0432.ccr-18-4032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-15KK0353
[Journal Article] Detection of circulating sarcoma tumor cells using a microfluidic chip-type cell sorter.2019
- Author(s)
  Hasegawa N, Takeda Nakamura I, Ueno T, Kojima S, Kawazu M, Akaike K, Okubo T, Takagi T, Suehara Y, Hayashi T, Saito T, Kaneko K, Mano H, Kohsaka S.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 20047-20047
- DOI
  10.1038/s41598-019-56377-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-15KK0353
[Journal Article] Single Patient Expanded Access制度を利用してLarotrectinibで治療を行ったNTRK融合遺伝子有する小児軟部肉腫の1例論文種類2019
- Author(s)
  加藤俊介, 藤村純也, 野崎由美, 山口茂夫, 高木辰哉, 林大久生, 齋藤剛, Henry Dahlia, Ku Nora, 末原義之
- Journal Title
  
  癌と化学療法
  
  Volume: 46 Pages: 1595-1597
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Journal Article] Molecular and clinicopathological analyses of esophageal carcinosarcoma with special reference to the differentiation mechanism.2019
- Author(s)
  Tsuyama S, Saito T, Akazawa Y, Yanai Y, Yatagai N, Akaike K, Hayashi T, Suehara Y, Takahashi F, Takamochi K, Hashimoto T, Kajiyama Y, Tsurumaru M, Fukunaga T, Yao T.
- Journal Title
  
  Virchows Archiv
  
  Volume: 475 Issue: 4 Pages: 415-424
- DOI
  10.1007/s00428-019-02643-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03789
[Journal Article] Protein Expression Profiles Corresponding to Histological Changes with Denosumab Treatment in Giant Cell Tumors of Bone.2019
- Author(s)
  Suehara Y, Okubo T, Kurihara T, Hayashi T, Kohsaka S, Kazuno S, Sano K, Hasegawa N, Miura Y, Akaike K, Kim Y, Takamochi K, Takahashi F, Ueno T, Kaneko K, Saito T.
- Journal Title
  
  Proteomics Clin Appl
  
  Volume: 13 Issue: 5 Pages: 1800147-1800147
- DOI
  10.1002/prca.201800147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-19K22694, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-19H03789, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-15KK0353
[Journal Article] Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p40.2018
- Author(s)
  Hayashi T, Takamochi K, Yanai Y, Mitani K, Tomita H, Mogushi K, Suehara Y, Takahashi F, Suzuki K, Saito T, Yao T. Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p40.
- Journal Title
  
  Hum Pathol
  
  Volume: 78 Pages: 79-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08674
[Journal Article] Role of sirolimus on the treatment of lymphangioleiomyomatosis: Increasing level of dysfunction of lymphangioleiomyomatosis-associated lymphatic vessels or cytoreduction2014
- Author(s)
  Kentaro Suina, Takuo Hayashi, Keiko Mitani, Kenji Suzuki, Kazuhisa Takahashi
- Journal Title
  
  Respiratory Investigation
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790363
[Journal Article] Reversed halo sign in tuberous sclerosis complex.2013
- Author(s)
  Kazuhiro Suzuki, Kuniaki Seyama, Takuo Hayashi, Yuki Yamashiro, Akihiko Shiraishi, Ryohei Kuwatsuru.
- Journal Title
  
  Case Rep Radiol.
  
  Volume: 2013:428501 Pages: 428501-428501
- DOI
  10.1155/2013/428501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790363
[Journal Article] Uterine angiosarcoma associated with lymphangioleiomyomatosis in a patient with tuberous sclerosis complex : an autopsy case report with immunohistochemical and genetic analysis2013
- Author(s)
  Hayashi T, Koike K, Kumasaka T, Saito T, Mitani K, Terao Y, Ogishima D, Yao T, Takeda S, Takahashi K, Seyama K
- Journal Title
  
  Hum Pathol
  
  Volume: 43 Pages: 1777-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790363
[Journal Article] A Rational Diagnostic Algorithm for the Identification of ALK Rearrangement in Lung Cancer : A Comprehensive Study of Surgically Treated Japanese Patients2013
- Author(s)
  Takamochi K, Takeuchi K, Hayashi T, Oh S, Suzuki K
- Journal Title
  
  PLoS One
  
  Volume: 1;8(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790363
[Journal Article] Reversed halo sign in tuberous sclerosis complex2013
- Author(s)
  Suzuki K, Seyama K, Hayashi T, Yamashiro Y, AShiraishi A, and Kuwatsuru R
- Journal Title
  
  Case Rep Radiol
  
  Volume: 2013 Pages: 428501-428501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790363
[Journal Article] Galectin-4, a novel predictor for lymph node metastasis in lung adenocarcinoma2013
- Author(s)
  Hayashi T, Saito T, Fujimura T, Hara K, Takamochi K, Mitani K, Mineki R, Kazuno S, Oh S, Ueno T, Suzuki K, Yao T
- Journal Title
  
  PLoS One
  
  Volume: 10;8(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790363
[Presentation] CAGE analysis identifies myostatin as a key regulator in muscular differentiation in high-grade sarcomas.2023
- Author(s)
  Hiroko Onagi, Raku Son, Akiko Oguchi, Kei Sano, Keita Sasa, Keisuke Akaike, Nobuhiko Hasegawa, Daisuke Kubota, Tatsuya Takagi, Takuo Hayashi, Muneaki Ishijima, Takashi Yao, Yoshiyuki Suehara, Yasuhiro Murakawa, Tsuyoshi Saito.
- Organizer
  2023 Annual Meeting, United States and Canadian Academy of Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] 骨軟部腫瘍におけるがんクリニカルシークエンスの実際.2023
- Author(s)
  末原義之、齋藤剛、林大久生、加藤俊輔、Marc Ladanyi.
- Organizer
  第60回埼玉県医学会総会
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.2022
- Author(s)
  T Nishimaki, K Kurokawa, T Miyawaki, T Asao, R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi.
- Organizer
  The 26th Congress of the Asian Pacific Society of Respirology(APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 臨床的治療実用可能な遺伝子変化の骨・軟部腫瘍における効率的同定法2022
- Author(s)
  原義之, 市田美夕, 五木田茶舞, 菊田一貴, 鳥越知明, 元井紀子, 安田政実, 平林かおる, 林大久生, 齋藤剛, 石島旨章
- Organizer
  第37回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] 非小細胞肺癌における抗ミュラー管ホルモン2型受容体（AMHR2）の発現と細胞増殖における役割の検討．2022
- Author(s)
  濃沼淑芳，光石陽一郎，高橋史行，Wira Winardi，金森幸一郎，林大久生，高持一矢，鈴木健司，高橋和久
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 骨軟部腫瘍における血漿中のcell-free RNAを用いた高感度融合遺伝子解析2022
- Author(s)
  長谷川延彦, 高阪真路, 岩田慎太郎, 林大久生, 齋藤剛, 佐々恵太, 窪田大介, 末原義之 , 高木辰哉, 石島旨章
- Organizer
  第95回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨軟部腫瘍におけるがんクリニカルシークエンスの実際2022
- Author(s)
  末原義之、齋藤剛、林大久生、加藤俊輔、Marc Ladanyi
- Organizer
  第60回埼玉県医学会総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 臨床的治療実用可能な遺伝子変化の骨軟部腫瘍における効率的同定法.2022
- Author(s)
  末原義之、市田美夕、五木田茶舞、菊田一貴、鳥越知明、元井紀子、安田政実、平林かおる、林大久生、齋藤剛、石島旨章
- Organizer
  第37回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Whole exome sequence/RNA sequenceによる腱滑膜巨細胞腫の新規融合遺伝子、遺伝子変異の同定2022
- Author(s)
  津田祐輔, 平田真, 小林寛, 河野博隆, 西田佳弘, 大隈知威, 阿江啓介, 川井章, 穴澤卯圭, 末原義之, 松田浩一
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.2022
- Author(s)
  Y Nagata, T Nagaoka, Y Kuroda, S Hotta, T Okuma, K Masuda, N Sakamoto, T Nishimaki, K Kurokawa, T Miyawaki, T Asao , R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi.
- Organizer
  The 26th Congress of the Asian Pacific Society of Respirology(APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] Whole exome sequence/RNA sequenceを用いた腱滑膜巨細胞腫の新規遺伝子変異の同定.2022
- Author(s)
  津田祐輔、平田真、小林寛、河野博隆、西田佳弘、大隈知威、阿江啓介、川井章、穴澤卯圭、末原義之、松田浩一
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Comprehensive transcriptome analysis of Cap site at the 5'end in osteosarcomas.2021
- Author(s)
  Sano K, Suehara Y, Oguchi A, Sasa K, Hayashi T, Kurihara T, AkaikeK, Kim Y, Okubo T, Kubota D, Takagi T, Murakawa Y, SaitoT.
- Organizer
  2021 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Comprehensive transcriptome analysis of Cap site at the 5'end in osteosarcomas.2021
- Author(s)
  Sano K, Suehara Y, Oguchi A, Sasa K, Hayashi T, Kurihara T, AkaikeK, Kim Y, Okubo T, Kubota D, Takagi T, Murakawa Y, SaitoT.
- Organizer
  2021 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Comprehensive transcriptome analysis of endoplasmic reticulum stress in osteosarcomas.2020
- Author(s)
  Kurihara T, Suehara Y, Hayashi T, Sano K, Sasa K, Kubota D, Akaike K, Okubo T, Kim Y, Saito T.
- Organizer
  European Society For Medical Oncology, ASIA 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨・軟部肉腫と小胞体ストレス応答との関連性2020
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 林大久生, 金栄智, 大久保武人, 高木辰哉, 金子和夫, 齋藤剛
- Organizer
  第53回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Expression Analysis of proteins associated with the regulation of c-kit and surgical material in gastrointestinal stromal tumor in which the effectiveness of HSP90 inhibitors has been pointed out.2020
- Author(s)
  Sasa K, Suehara Y, Okubo T, Hayashi T, Sano K, Kurihara T, Akaike K, Ishii M, Kim Y, Kaneko K, Saito T.
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 優秀演題賞：高悪性骨肉腫の新規治療標的にいてのサンプリング部位による変化検討2020
- Author(s)
  末原義之, Alex Deepu, 林大久生, Bowman Anita, Middha Sumit, Zehir Ahmet, Wang Lu, Meyers Paul, Healey John, Hameed Meera, Ladanyi Marc
- Organizer
  第58回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] 優秀演題賞：高悪性骨肉腫の新規治療標的にいてのサンプリング部位による変化検討2020
- Author(s)
  末原義之, Alex Deepu, 林大久生, Bowman Anita, Middha Sumit, Zehir Ahmet, Wang Lu, Meyers Paul, Healey John, Hameed Meera, Ladanyi Marc
- Organizer
  第58回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨肉腫と小胞体ストレス応答との関連性2020
- Author(s)
  栗原大聖, 末原義之, 佐々恵太, 佐野圭, 赤池慶祐, 窪田大介, 林大久生, 高木辰哉, 金子和夫, 齋藤剛
- Organizer
  第93日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Protein profiling of cell lines and surgical specimens reveal that heat shock protein 90-beta may be involved in the malignancy of synovial sarcoma.2020
- Author(s)
  Sano K, Suehara Y, Sasa K, Kurihara T, Akaike K, Ishii M, Kim Y, Okubo T, Hayashi T, Kaneko K, Saito T.
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] シンポジウム:骨・軟部腫瘍研究の最前線　ゲノムシークエンシング　骨軟部腫瘍におけるクリニカルシークエンス2020
- Author(s)
  末原義之、林大久生、加藤俊介、Marc Ladanyi、齋藤剛
- Organizer
  第35回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Protein profiling of cell lines and surgical specimens reveal that heat shock protein 90-beta may be involved in the malignancy of synovial sarcoma.2020
- Author(s)
  Sano K, Suehara Y, Sasa K, Kurihara T, Akaike K, Ishii M, Kim Y, Okubo T, Hayashi T, Kaneko K, Saito T.
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Comprehensive transcriptome analysis of endoplasmic reticulum stress in osteosarcomas.2020
- Author(s)
  Kurihara T, Suehara Y, Hayashi T, Sano K, Sasa K, Kubota D, Akaike K, Okubo T, Kim Y, Saito T.
- Organizer
  European Society For Medical Oncology, ASIA 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Detection of fusion genes in inflammatory myofibroblastic tumor by NanoString and immunohistochemistry.2020
- Author(s)
  Kurihara T, Suehara Y, Sano K, Akaike K, Hayashi T, Hasegawa N, Takagi T, Okubo T, Yao T, Kaneko K, Saito T.
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Detection of fusion genes in inflammatory myofibroblastic tumor by NanoString and immunohistochemistry.2020
- Author(s)
  Kurihara T, Suehara Y, Sano K, Akaike K, Hayashi T, Hasegawa N, Takagi T, Okubo T, Yao T, Kaneko K, Saito T.
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Expression Analysis of proteins associated with the regulation of c-kit and surgical material in gastrointestinal stromal tumor in which the effectiveness of HSP90 inhibitors has been pointed out.2020
- Author(s)
  Sasa K, Suehara Y, Okubo T, Hayashi T, Sano K, Kurihara T, Akaike K, Ishii M, Kim Y, Kaneko K, Saito T.
- Organizer
  2020 Annual Meeting of Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Gastric adenocarcinoma of fundic-gland differentiation2020
- Author(s)
  Ueyama H, Yao T, Akazawa Y, Hayashi T, Utsunomiya H, Uchida R, Abe D, Oki S, Suzuki N, Ikeda A, Yatagai N, Komori H, Takeda T, Matsumoto K, Ueda K, Matsumoto K, Asaoka D, Hojo M, Nagahara A
- Organizer
  United European Gastroenterology Week 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08393
[Presentation] シンポジウム:骨・軟部腫瘍研究の最前線　ゲノムシークエンシング　骨軟部腫瘍におけるクリニカルシークエンス2020
- Author(s)
  末原義之、林大久生、加藤俊介、Marc Ladanyi、齋藤剛
- Organizer
  第35回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System.2020
- Author(s)
  Kurihara T, Suehara Y, Akaike K, Hayashi T, Kohsaka S, Hasegawa N, Takagi T, Okubo T, Kim Y, Yao T, Kaneko K, Saito T.
- Organizer
  USCAP, the 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System.2020
- Author(s)
  Kurihara T, Suehara Y, Akaike K, Hayashi T, Kohsaka S, Hasegawa N, Takagi T, Okubo T, Kim Y, Yao T, Kaneko K, Saito T.
- Organizer
  USCAP, the 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] anoString analyses of tyrosine kinase fusion genes in IMT / IPT2019
- Author(s)
  Kurihara T, Suehara Y, Sano K, Akaike K, Hayashi T, Kohsaka S, Hasegawa N, Takagi T, Okubo T, Yao T, Kaneko K Saito T.
- Organizer
  Connective Tissue Oncology Society, 24th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Nanostringを用いたinflammatory myofibroblastic tumor/Inflammatory pseudotumorにおける融合遺伝子解析.2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 林大久生, 長谷川延彦, 高阪真路, 八尾隆史, 金子和夫, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 紡錘形細胞肉腫のCAGE法(cap analysis of gene expression法)を用いた網羅的遺伝子発現解析.2019
- Author(s)
  佐野圭, 末原義之, 林大久生, 村川泰裕, 栗原大聖, 赤池慶祐, 高木辰哉, 金栄智, 大久保武人, 金子和夫, 齋藤剛.
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] メタボロミクスにおけるアドリアマイシン耐性骨肉腫とペントースリン酸系回路との関係性.2019
- Author(s)
  佐々恵太, 末原義之, 赤池慶祐, 高ひかり, 林大久生, 大久保武人, 金栄智, 金子和夫, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] シンポジウム：骨・軟部腫瘍のゲノム医療とカウンセリング_軟部肉腫のTyrosine kinase融合遺伝子・遺伝子変異体の探索2019
- Author(s)
  末原義之, 高阪真路, 栗崎愛子, 林大久生, 赤池慶祐, 佐藤信吾, 小林英介, 金子和夫, 間野博行, 齋藤剛.
- Organizer
  52回日本整形外科学会骨・軟部腫瘍学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Efficacy of IRE1α-XBP1 inhibitors in osteosarcomas2019
- Author(s)
  Kurihara T, Suehara Y, Hayashi T, Takagi T, Akaike K, Sano K, Kaneko K, Saito T.
- Organizer
  Connective Tissue Oncology Society, 24th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨軟部肉腫におけるマイクロ流路チップ・セルソーターを使用した循環腫瘍細胞の同定と次世代シーケンシング2019
- Author(s)
  長谷川延彦, 高阪真路, 中村育子, 末原義之, 高木辰哉, 林大久生, 斎藤剛, 金子和夫, 間野博行.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Relationship with adriamycin-resistant osteosarcomas and the pentose phosphate pathway using metabolomic approaches2019
- Author(s)
  Sasa K, Suehara Y, Akaike K, Hayashi T, Taka H, Kim Y, Okubo T Kaneko K, Saito T.
- Organizer
  20th International Symposium on Limb Salvage
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Comparative analysis of protein profiles of prognosis-associated proteins and KIT-related proteins in gastrointestinal stromal tumor2019
- Author(s)
  Suehara Y, Sasa K, Okubo T, Hayashi T, Sano K, Kurihara T, Akaike K, Ishii M, Kim Y, Kaneko K, Saito T.
- Organizer
  European Society For Medical Oncology ASIA, 2019 Annual Meeting,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 軟部肉腫pazopanib著効例の12q13-14遺伝子増幅変化.2019
- Author(s)
  末原義之, 高阪真路, 山口茂夫, 林大久生, 栗原大聖, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, 加藤俊介.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Efficacy of IRE1α-XBP1 inhibitors in osteosarcomas2019
- Author(s)
  Kurihara T, S Suehara Y, Hayashi T, Takagi T, Akaike K, Sano K, Kaneko K, Saito T.
- Organizer
  Connective Tissue Oncology Society, 24th Annual Meeting, November 13-16, 2019, Tokyo, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] High-throughput analysis of transcriptional starting point and identification of promoter usage in spindle cell sarcomas.2019
- Author(s)
  Sano K, Suehara Y, Hayashi T, Kurihara T, Akaike K, Oguchi A, Takagi T, Kim Y, Okubo T, Murakawa Y, Kaneko K, Saito T.
- Organizer
  Connective Tissue Oncology Society, 24th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Protein expression analysis by regulating c-kit and KCTD12 expression in Gastrointestinal stromal tumor.2019
- Author(s)
  Sasa K, Suehara Y, Okubo T, Hayashi T, Sano K, Kurihara T, Akaike K, Ishii M, Kim Y, Kaneko K, Saito T.
- Organizer
  Connective Tissue Oncology Society, 24th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 軟部肉腫のROS1融合遺伝子同定とその機能解析.2019
- Author(s)
  末原義之, 高阪真路, 林大久生, 赤池慶祐, 佐藤信吾, 小林英介, 金栄智, 大久保武人, 金子和夫, 間野博行, 齋藤剛.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 軟部腫瘍におけるがんクリニカルシークエンス検査の比較.2019
- Author(s)
  末原義之, 林大久生, 山口茂夫, 金子和夫, 齋藤剛, 加藤俊介.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Nanostringを用いたIMT/IPTにおけるチロシンキナーゼ融合遺伝子の解析2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 長谷川延彦, 林大久生, 高阪真路, 高木辰哉, 八尾隆史, 金子和夫, 斎藤剛.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨・軟部肉腫における血中循環腫瘍細胞の同定.2019
- Author(s)
  長谷川延彦, 高阪真路, 末原義之, 赤池慶祐, 大久保武人, 高木辰哉, 林大久生, 齋藤剛, 金子和夫, 間野博行.
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Gastrointestinal stromal tumorにおけるc-kit、KCTD12発現調節に伴ったタンパク質発現解析.2019
- Author(s)
  佐々恵太, 末原義之, 佐野圭, 栗原大聖, 石井翠, 金栄智, 赤池慶祐, 大久保武人, 林大久生, 齋藤剛, 金子和夫
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Integrative analysis including whole genome sequencing, transcriptome sequencing, and phospho-protein expression profiling of super responder to pazopanib in high-grade soft tissue sarcomas.2019
- Author(s)
  Suehara Y, Kohsaka S, Yamaguchi S, Hayashi T, Kurihara T, Akaike K, Ueno T, Kojima S, Ikegami M, Mizuno S, Kaneko K , Kato S, Mano H, Saito T.
- Organizer
  20th International Symposium on Limb Salvage
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨肉腫に対するIRE1α阻害剤のin vivoとin vitroでの有効性.2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 林大久生, 金栄智, 大久保武人, 金子和夫, 齋藤剛.
- Organizer
  第92回日本整形外科学会学術総会, パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-19K22694
[Presentation] Clinical sequencing revealed the ALK-related fusion gene in an infantile soft tissue sarcoma, leading to molecular diagnosis and ALK-targeted therapy.2019
- Author(s)
  Kaino A, Niizuma H, Suehara Y, Katayama S, Kato S, Saito T, Hayashi T, Moriya K, Irie M, Rikiishi T, Sasahara Y, Kure S.
- Organizer
  第61回日本小児血液・がん学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] Clinicopathological characteristics of lung adenocarcinoma with EGFR compound mutations.2019
- Author(s)
  林大久生, 高阪真路, 高持一矢, 原貴恵子, 高橋史行, 末原義之, 齋藤剛, 鈴木健司, 間野博行, 八尾隆史
- Organizer
  United States and Canadian Academy of Pathology (USCAP) 108th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08674
[Presentation] CAGE法を用いた肺腺癌におけるNKX2.1遺伝子発現解析と臨床病理学的検討.2019
- Author(s)
  佐野圭, 林大久生, 高持一矢, 細谷理樹, 原貴恵子, 末原義之, 鈴木健司, 齋藤剛.
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] メタボロミクスを用いたアドリアマイシン耐性骨肉腫における代謝変動の解析.2019
- Author(s)
  佐々恵太, 末原義之, 赤池慶祐, 高ひかり, 林大久生, 大久保武人, 金栄智, 金子和夫, 齋藤剛.
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 軟部肉腫pazopanib著効例の特徴的遺伝子増幅変化.2019
- Author(s)
  末原義之, 高阪真路, 山口茂夫, 林大久生, 栗原大聖, 赤池慶祐, 金子和夫, 齋藤剛, 間野博行, 加藤俊介.
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 骨肉腫に対するIRE1α阻害剤のin vivoとin vitroでの有効性.2019
- Author(s)
  栗原大聖, 末原義之, 赤池慶祐, 林大久生, 金栄智, 大久保武人, 金子和夫, 齋藤剛.
- Organizer
  第92回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03789
[Presentation] 病理検体に影響を与える検体処理因子2019
- Author(s)
  林大久生
- Organizer
  第29回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08674
[Presentation] 肺腺癌におけるゲノム・病理組織学の統合的解析：ERBB2, METex14, BRAF, MAP2K1陽性腺癌の臨床病理学的特徴2018
- Author(s)
  林大久生, 高阪真路, 高持一矢, 末原義之, 茂櫛薫, 高橋史行, 齋藤剛, 鈴木健司, 間野博行, 八尾隆史
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K08674
[Presentation] Integrated histologic and genomic analyses of lung adenocarcinoma in never or light smokes identify unique histological characteristics of MET exon 14 skipping-positive tumors2018
- Author(s)
  林大久生, 高阪真路, 高持一矢, 末原義之, 茂櫛薫, 高橋史行, 齋藤剛1, 鈴木健司, 間野博行7, 八尾隆史
- Organizer
  第29回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08674
[Presentation] リンパ脈管筋腫症の病理2013
- Author(s)
  林大久生
- Organizer
  第22回Tokyo lung conference U40
- Place of Presentation
  東京
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24790363
[Presentation] Proteomic approach revealed Galectin-4 as a lymph node metastasis predictor in lung adenocarcinoma2013
- Author(s)
  Hayashi T, et al
- Organizer
  102nd USCAP Annual Meeting
- Place of Presentation
  Baltimore Convention Center Baltimore, MD
- Data Source
  KAKENHI-PROJECT-24790363
[Presentation] Proteomic approach revealed Galectin-4 as a lymph node metastasis predictor in lung adenocarcinoma.2013
- Author(s)
  Takuo Hayashi, et al.
- Organizer
  102nd USCAP Annual Meeting
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-24790363
[Presentation] リンパ脈管筋腫症の病理
- Author(s)
  林　大久生
- Organizer
  第22回　Tokyo Lung Conference U40
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24790363
[]

1. 齋藤剛 (80439736)

# of Collaborated Projects: 5 results

# of Collaborated Products: 68 results
2. Suehara Yoshiyuki (70509405)

# of Collaborated Projects: 3 results

# of Collaborated Products: 69 results
3. 高阪真路 (00627119)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
4. 北野滋久 (60402682)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. Ueyama Hiroya (60621935)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 高持一矢 (30397369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 小林英介 (40365292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. 永原章仁 (00266040)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 高橋和久 (80245711)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. 細川正人 (60722981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 菊田一貴 (30383798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 五木田茶舞 (60422490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 八尾隆史 (20243933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 赤澤陽一 (80822006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 光石陽一郎 (10647001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 白石友一 (70516880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 宿谷威仁 (90529174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 鈴木一廣 (20338370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 村川泰裕 (50765469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 松永浩子 (10592024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YAMAGUCHI Shigeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 高橋史行

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
23. 田島健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 加藤俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

HAYASHI TAKUO 林 大久生

Hayashi Takuo 林 大久生

Research Projects

Research Products

Co-Researchers

網羅的遺伝子発現解析技術を用いたH.pylori未感染胃癌の発癌機構の解明

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Developing a model to predict response to immune checkpoint inhibitor using machine learning

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Development of personalized medicine for lung cancer using next-generation transcriptomePrincipal Investigator

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Carcinogenesis of gastric adenocarcinoma of fundic-gland type

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小細胞肺癌における酸化ストレス応答系の破綻機序の解明

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Elucidation of the molecular mechanism of immunotherapy treatment resistance by microtissue multidisciplinary sequencePrincipal Investigator

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Development of novel treatment based on functional analysis of endoplasmic reticulum stress in bone and soft tissue sarcoma

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Functional analysis and discovery of molecular targets in bone and soft tissue sarcoma based on cancer clinical sequence

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Functional analysis of lung cancers with RASA1 mutationsPrincipal Investigator

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リンパ脈管筋腫症におけるリンパ管内皮のプロスタグランジン発現と病態進展への関与Principal Investigator

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Do LAM cells express VEGF-D through the activation of mTORC1/ HIF-1a/ VEGF pathway?Principal Investigator

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[Book] PrecisionMedicine 特集「がんゲノム医療の基礎と臨床」各論 病理診断医の立場から見たがんクリニカルシークエンス検査 -MSK-IMPACT日本導入の経験から-2019

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[Book] 呼吸(0286-9314)31巻9号【最近10年で最も進歩した研究分野を検証する】リンパ脈管筋腫症(LAM)2012

Author(s)

Data Source

HAYASHI TAKUO 林大久生

Hayashi Takuo 林大久生

[Book] PrecisionMedicine　特集「がんゲノム医療の基礎と臨床」各論病理診断医の立場から見たがんクリニカルシークエンス検査 -MSK-IMPACT日本導入の経験から-2019