Yamada Hiroyuki 山田博之

Researcher Number	70713650
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator p38 / p38 MAPK / ポドサイト / MAPK / 巣状糸球体硬化症 / 糸球体上皮細胞 / ハンプ / 内皮障害 / ANP / ナトリウム利尿ペプチド … More Except Principal Investigator … More 救急医療 / 敗血症 / 低代謝 / 休眠 / 冬眠 Less

ポドサイト障害におけるp38 MAPKを介した細胞内タンパク分解機構の解明Principal Investigator
- Principal Investigator
  
  山田博之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyoto University
The Impact of Hibernation-like States on Sepsis: An Investigation
- Principal Investigator
  
  大鶴繁
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyoto University
ポドサイト障害におけるp38 MAPKの意義の解明Principal Investigator
- Principal Investigator
  
  山田博之
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyoto University
Association of p38 MAPK with natriuretic peptide receptors in renal glomeruliPrincipal Investigator
- Principal Investigator
  
  Yamada Hiroyuki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kyoto University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Beyond 2D: A scalable and highly sensitive method for a comprehensive 3D analysis of kidney biopsy tissue2024
- Author(s)
  Yamada Hiroyuki、Makino Shin-ichi、Okunaga Issei、Miyake Takafumi、Yamamoto-Nonaka Kanae、Oliva Trejo Juan Alejandro、Tominaga Takahiro、Empitu Maulana A、Kadariswantiningsih Ika N、Kerever Aurelien、Komiya Akira、Ichikawa Tomohiko、Arikawa-Hirasawa Eri、Yanagita Motoko、Asanuma Katsuhiko
- Journal Title
  
  PNAS Nexus
  
  Volume: 3 Issue: 1 Pages: 433-445
- DOI
  10.1093/pnasnexus/pgad433
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15227, KAKENHI-PROJECT-22K07543, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-23K27616
[Journal Article] Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi2023
- Author(s)
  Sugioka Sayaka、Yamada Hiroyuki、Ishii Akira、Kato Yukiko、Yamada Ryo、Mori Keita P.、Ohno Shoko、Handa Takaya、Ikushima Akie、Ishimura Takuya、Osaki Keisuke、Tokudome Takeshi、Matsusaka Taiji、Nebreda Angel R.、Yanagita Motoko、Yokoi Hideki
- Journal Title
  
  Kidney International
  
  Volume: 104 Issue: 3 Pages: 508-525
- DOI
  10.1016/j.kint.2023.06.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15226, KAKENHI-PROJECT-23K15227, KAKENHI-PROJECT-22K08310, KAKENHI-PROJECT-23K07717, KAKENHI-PROJECT-20K08505, KAKENHI-PROJECT-23K21437
[Journal Article] Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFκΒ pathway inhibition2023
- Author(s)
  Ishimura Takuya、Ishii Akira、Yamada Hiroyuki、Osaki Keisuke、Toda Naohiro、Mori Keita P.、Ohno Shoko、Kato Yukiko、Handa Takaya、Sugioka Sayaka、Ikushima Akie、Nishio Haruomi、Yanagita Motoko、Yokoi Hideki
- Journal Title
  
  Kidney International
  
  Volume: 104 Issue: 5 Pages: 929-942
- DOI
  10.1016/j.kint.2023.08.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15226, KAKENHI-PROJECT-23K15227, KAKENHI-PROJECT-22K08310, KAKENHI-PROJECT-23K07717, KAKENHI-PROJECT-23K27616
[Journal Article] Inhibition of Importin-α?Mediated Nuclear Localization of Dendrin Attenuates Podocyte Loss and Glomerulosclerosis2023
- Author(s)
  Empitu Maulana A.、Kikyo Mitsuhiro、Shirata Naritoshi、Yamada Hiroyuki、Makino Shin-ichi、Kadariswantiningsih Ika N.、Aizawa Masashi、Patrakka Jaakko、Nishimori Katsuhiko、Asanuma Katsuhiko
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 34 Issue: 7 Pages: 1222-1239
- DOI
  10.1681/asn.0000000000000150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15227, KAKENHI-PROJECT-23K27614
[Journal Article] Nephrotoxicity associated with anticancer agents: perspective on onconephrology from nephrologists2023
- Author(s)
  Takeshi Matsubara, Hideki Yokoi, Hiroyuki Yamada, Motoko Yanagita
- Journal Title
  
  Int J Clin Oncol
  
  Volume: なし Issue: 5 Pages: 1-12
- DOI
  10.1007/s10147-023-02307-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08350, KAKENHI-PROJECT-23K15227, KAKENHI-PROJECT-21K16188
[Journal Article] Sacubitril/valsartan ameliorates renal tubulointerstitial injury through increasing renal plasma flow in a mouse model of type 2 diabetes with aldosterone excess2023
- Author(s)
  Nishio Haruomi、Ishii Akira、Yamada Hiroyuki、Mori Keita P、Kato Yukiko、Ohno Shoko、Handa Takaya、Sugioka Sayaka、Ishimura Takuya、Ikushima Akie、Inoue Yui、Minamino Naoto、Mukoyama Masashi、Yanagita Motoko、Yokoi Hideki
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 38 Issue: 11 Pages: 2517-2527
- DOI
  10.1093/ndt/gfad098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-23K15226, KAKENHI-PROJECT-23K15227, KAKENHI-PROJECT-22K08310, KAKENHI-PROJECT-23K07717
[Journal Article] Intestinal Bacterial Translocation Contributes to Diabetic Kidney Disease.2022
- Author(s)
  Linh HT, Iwata Y, Senda Y, Sakai-Takemori Y, Nakade Y, Oshima M, Nakagawa-Yoneda S, Ogura H, Sato K, Minami T, Kitajima S, Toyama T, Yamamura Y, Miyagawa T, Hara A, Shimizu M, Furuichi K, Sakai N, Yamada H, Asanuma K, Matsushima K, Wada T.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: - Issue: 6 Pages: 1105-1119
- DOI
  10.1681/asn.2021060843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-21K08224, KAKENHI-PROJECT-21K16188, KAKENHI-PROJECT-20KK0191, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-21K19479, KAKENHI-WRAPUP-22H04906
[Journal Article] Optimal Evidence Grading of Simultaneous Use of Hypertonic Saline and Furosemide for Fluid Overload2022
- Author(s)
  Kitajima Naoki、Yamada Hiroyuki、Minami Takuma、Ohtsuru Shigeru
- Journal Title
  
  Critical Care Medicine
  
  Volume: 50 Issue: 4 Pages: 405-406
- DOI
  10.1097/ccm.0000000000005419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17860, KAKENHI-PROJECT-21K16188
[Journal Article] Global Perspectives in Acute Kidney Injury: Japan2022
- Author(s)
  Hiroyuki Yamada , Motoko Yanagita
- Journal Title
  
  Kidney360
  
  Volume: 5 Issue: 6 Pages: 1099-1104
- DOI
  10.34067/kid.0007892021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16188
[Journal Article] 【腎疾患治療薬update】(第5章)期待される薬剤急性腎障害の予防低用量カルペリチド(心房性ナトリウム利尿ペプチド:ANP)2021
- Author(s)
  山田博之
- Journal Title
  
  腎と透析
  
  Volume: 91 Pages: 765-768
- Data Source
  KAKENHI-PROJECT-21K16188
[Journal Article] Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model2021
- Author(s)
  Fukuta M, Suzuki K, Kojima S, Yabe Y, Suzuki K, Iida K, Yamada H, Makino S, Iwata A, Tanaka S, Iwamoto T, Suto A, Nakagomi D, Wakashin H, Maezawa Y, Maezawa Y, Takemoto M, Asanuma K, Nakajima H.
- Journal Title
  
  Lupus Sci Med.
  
  Volume: 8 Issue: 1 Pages: 426-426
- DOI
  10.1136/lupus-2020-000426
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08797, KAKENHI-PROJECT-21K16188, KAKENHI-PROJECT-21K16297
[Journal Article] 特集腎疾患-エキスパートへの質問で学ぶ診療のキホンと最新情報利尿薬やその他の新薬の有効性と注意すべき副作用心不全やAKIにANP(心房性ナトリウム利尿ペプチド)を投与すべきか否か? またその効果はあるのか? について教えてください2021
- Author(s)
  山田博之、横井秀基
- Journal Title
  
  medicina
  
  Volume: 58 Issue: 10 Pages: 1636-1640
- DOI
  10.11477/mf.1402227821
- ISSN
  0025-7699, 1882-1189
- Year and Date
  2021-09-10
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] ポドサイト特異的p38 MAPK & GC-Aダブルノックアウトマウスの腎病変におけるポドサイト-内皮連関の解明2022
- Author(s)
  杉岡清香 , 山田博之 , 加藤有希子 , 石井輝 , 森慶太 , 大崎啓介 , 徳留健 , 松阪泰二 , 柳田素子 , 横井秀基
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] 拡張型心筋症モデルマウスを用いた心腎連関の機序解明2022
- Author(s)
  石村拓也 , 石井輝 , 山田博之 , 中川靖章 , 大野祥子 , 生島昭恵 , 杉岡清香 , 半田貴也 , 桑原宏一郎 , 柳田素子 , 横井秀基
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] Subcellular localization of dendrin modulates the fate of podocyte injury and glomerulosclerosis2022
- Author(s)
  Empitu Maulana A. , Makino Shin-ichi , Yamada Hiroyuki , Kadariswantiningsih Ika N. , Aizawa Masashi , Asanuma Katsuhiko
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] The Ambivalent Role of Ccl5 in Podocyte Injury and Glomerular Disease2022
- Author(s)
  Kadariswantiningsih Ika N. , Empitu Maulana A. , Yamada Hiroyuki , Makino Shin-Ichi , Aizawa Masashi , Tatsumoto Narihito , Asanuma Katsuhiko
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] 組織透明化による糸球体およびポドサイトの3次元病理診断2022
- Author(s)
  山田博之 , 牧野慎市 , 柳田素子 , 淺沼克彦
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] Membrane-Associated Guanylate Kinase Inverted 2は、腎糸球体ポドサイトのスリット膜構造維持に必須である2021
- Author(s)
  山田博之
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K16188
[Presentation] 未踏の頂き AKIへの挑戦 ICUにおけるケアバンドル2021
- Author(s)
  山田博之
- Organizer
  日本腎臓学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K16188

1. 大鶴繁 (60437225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 砂川玄志郎 (70710250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 高谷悠大 (60828903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SUTO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SUZUKI Kotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MATSUBARA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 加藤有希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 松島綱治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岩本太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 南卓馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 向山政志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamada Hiroyuki 山田 博之

Research Projects

Research Products

Co-Researchers

ポドサイト障害におけるp38 MAPKを介した細胞内タンパク分解機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Impact of Hibernation-like States on Sepsis: An Investigation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ポドサイト障害におけるp38 MAPKの意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association of p38 MAPK with natriuretic peptide receptors in renal glomeruliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Beyond 2D: A scalable and highly sensitive method for a comprehensive 3D analysis of kidney biopsy tissue2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFκΒ pathway inhibition2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Importin-α?Mediated Nuclear Localization of Dendrin Attenuates Podocyte Loss and Glomerulosclerosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nephrotoxicity associated with anticancer agents: perspective on onconephrology from nephrologists2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sacubitril/valsartan ameliorates renal tubulointerstitial injury through increasing renal plasma flow in a mouse model of type 2 diabetes with aldosterone excess2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intestinal Bacterial Translocation Contributes to Diabetic Kidney Disease.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimal Evidence Grading of Simultaneous Use of Hypertonic Saline and Furosemide for Fluid Overload2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global Perspectives in Acute Kidney Injury: Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 【腎疾患治療薬update】(第5章)期待される薬剤 急性腎障害の予防 低用量カルペリチド(心房性ナトリウム利尿ペプチド:ANP)2021

Author(s)

Journal Title

Data Source

[Journal Article] Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model2021

Author(s)

Journal Title

Yamada Hiroyuki 山田博之

[Journal Article] 【腎疾患治療薬update】(第5章)期待される薬剤急性腎障害の予防低用量カルペリチド(心房性ナトリウム利尿ペプチド:ANP)2021