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TSUCHIYA Tomofusa  土屋 友房

ORCIDConnect your ORCID iD *help
Researcher Number 80012673
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2012: 立命館大学, 薬学部, 教授
2008 – 2010: Okayama University, 大学院・医歯薬学総合研究科, 教授
2006: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 大学院医歯薬学総合研究科, 教授
2005 – 2006: 岡山大学, 大学院・医歯薬学総合研究科, 教授
2004: 岡山大学, 薬学部, 教授 … More
1986 – 2002: 岡山大学, 薬学部, 教授
1986: 岡山大, 薬学部, 教授
1985: 岡山大学, 薬, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / 物質生物化学 / Bacteriology (including Mycology) / Environmental pharmacy
Except Principal Investigator
医学一般 / Biological pharmacy / Biological pharmacy
Keywords
Principal Investigator
ATPase / 腸炎ビブリオ / カチオン共役 / Active transport / MRSA / ATP / DnaA / アンチポーター / 能動輸送 / Primary structure … More / 一次構造 / 機能ドメイン / ADP / 緑膿菌 / イオン輸送系 / 黄色ブドウ球菌 / Functional domain / Antiporter / Symporter / Cation coupling / 遺伝子 / 多剤排出ポンプ / 多剤耐性菌 / DNA複製 / ORC / 構造と機能 / シンポーター / ナトリウム / 遺伝子解析 / Changes in function / Amino acid substitution / Transport carrier / 変異の同定 / 機能の変化 / 一次構造の変化 / 機能変化 / アミノ酸置換 / 輸送担体 / skyrin / K.pneumoniae / inhibitor of efflux pump / analysis of total picture / P.aeruginosa / multidrug efflux pump / multidrug resistant bacteria / 有効物質 / ポンプ阻害剤 / 系統的解析 / 耐性系阻害薬 / 抗生物質 / 感染症 / 排出ポンプ阻害物質 / スカイリン / 肺炎桿菌 / 排出ポンプ阻害剤 / 全体像の解析 / regulation of activity / DNA replication / Cdc6p / ATP結合 / 開始因子 / 癌 / 結晶構造解析 / 酸性リン脂質 / リン脂質 / 活性調節 / Patch clamp / Vibrio parahaemolyticus / Pseudomonas aeruginosa / Ion transport / Drug extrusion system / パッチクランプ / 薬剤排出系 / Unity and diversity / Structure and function / アンチポート系 / シンポート系 / 統一性と多様性 / 能動輸送系 / ion transport system / antiporter / halotorelance / Na^+ transport system / Staphylococcus aureus / Vibro parahaemolyticus / イオン輸送 / Na_+輸送系 / 耐塩性 / Na+輸送系 / Energy coupling / 機能部位 / エネルギー共役 / Genes / Growth inhibition / Serine / 生育阻害 / セリン / Transport regulation / Transport protein / Transport mechanism / 輸送系の構造 / 輸送制御 / 輸送タンパク質 / 輸送機構 / 【H^+】 / 【Na^+】 / カチオン / 抗MRSA作用 / 耐性菌 / バイオフィルム阻害物質 / 抗菌物質 / VRE / バイオフィルム形成阻害 / 抗菌薬 / 医薬品開発 / 耐性系 / 試験管内 / 制御 / CdC6p / クローニング / アンチポ-タ / シンポータ / チャネル / トランスポータ / イオン / 共役系 / ATP合成 / エネルギ-転換 / 大腸菌 / ロダネ-ゼ / 遺伝子群 / pH感受性 / セリン感受性 / フォルマイシン / アデノシン輸送 … More
Except Principal Investigator
鉄酸化細菌 / スルホロブス / 遺伝子導入 / ベン毛モーター / H^+ATPアーゼ / 腸炎ビブリオ / アーキロドプシン / ハロバクテリア / Gene therapy / Transplantation / Primary culture / Cerebellum / Retrovirus-mediated gene transfer / 神経疾患治療 / ウイルス感染 / 移植 / 中枢神経系 / ベクター / 小脳 / 小脳初代細胞 / 細胞移植 / レトロウイルス / Transfection / Riboprobes / Specific mRNA quantitation / Gene expression / Synapse formation / Neurite extension / 神経系ネットワーク / 遺伝子発現制御 / RNA-RNAハイブリダイゼーション / 脳内mRNA定量 / 脳内遺伝子発現 / 脳特異的cDNA / マウス脳cDNAバンク / 脳内への外来遺伝子導入 / レトロウイルスベクター / トランスフェクション / プロテインキナーゼ阻害剤 / リボプローブによるmRNA定量 / 遺伝子発現 / シナプス形成 / 神経突起伸長 / cloning / structure-function relation / Ca pump / transporter / water channel / ion channel / クローニング / 構造・機能相関 / カルシウムポンプ / トランスポータ / 水チャネル / イオンチャネル / バクテリオロドプシン / チトクロムc-552 / Na^+排出型呼吸鎖 / ハロバクタリア / 多剤耐性菌 / RND / 肺炎桿菌 / 多剤排出ポンプ / 細胞生物学 / Cdc6p / ORC / DnaA / ATPase / ATP結合 / 開始因子 / 癌 / DNA複製 / チトクロム酸化酵素 / H^+ PPiアーゼ / H^+ ATPアーゼ / 液胞 Less
  • Research Projects

    (26 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (37 People)
  •  Identification of multidrug resistance mechanisms in Klebsiella pneumoniae and analysis of the function of these gene products.

    • Principal Investigator
      OGAWA Wakano
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  Analysis of multidrug resistance systems in multidrug resistant bacteria and development of drugs effective on the resistant bacteriaPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Okayama University
  •  Systematic analysis of multidrug efflux pumps in multidrug resistant bacteria and development of pump inhibitorPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      OKYAMA UNIVERSITY
  •  ガン化に伴うDNA複製開始制御の変化と、その抗がん剤の新規ターゲットとしての応用Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Okayama University
  •  複製開始蛋白質DnaAのX線結晶構造解析による高次構造の決定と機能部位解析

    • Principal Investigator
      黒田 照夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Okayama University
  •  Tne initiator of chromosomal DNA replication in E. coli.Principal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa, 黒田 照夫
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Unity and diversity in active transport in cell membransPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  Structure and function of drug- and ion-extrusion systems in bacteriaPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  イオン駆動型トランスポーターとチャネルの構造・機能協関Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  Channel-Transporter Correlation

    • Principal Investigator
      OKADA Yasunobu
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Characteristics of ion tranport systems in Vibrio parahaemolyticus and Staphylococcus aureusPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  Molecular mechanism of energy coupling in active transportPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okayama University
  •  Na^+/H^+アンチポーターとNa^+/H^+/基質シンポーターの共役系の解析Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  Structure and mechanism in cation-coupled transport systemsPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okayama University
  •  Analysis of factors involved in serine-sensitivity in bacterial cellsPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  大腸菌のセリン感受性とpH感受性に関与する遺伝子群の解析Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  腸炎ビブリオのエネルギ-転系の特殊性Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  腸炎ビブリオ細胞膜におけるアデノシン・フォルマイシン輸送系の解析Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  異環境生物のエネルギー

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  異環境生物のエネルギー

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Structure and mechanism in active transport systems for sugars, amino acids and ions.Principal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  異環境生物のエネルギー

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Application of retrovirus-mediated gene transfer and cell transplantation for studying the structure and function of nervous systems at the level of gene action

    • Principal Investigator
      TSUDA Masaaki
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      医学一般
    • Research Institution
      Okayama University, Faculty of Pharmaceutical Sciences
  •  Approaches to study the structure and function of nervous systems at the level of gene expression

    • Principal Investigator
      TSUDA Masaaki
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University, Fuculty of Pharmaceutlcal Sciences
  •  Alterations in the primary structure of the active transport carrier and changes in the functionPrincipal Investigator

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Okayama University
  •  カチオン輸送蛋白質のカチオン認識機構に関する遺伝子工学的解析Principal Investigator

    • Principal Investigator
      土屋 友房
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Okayama University

All 2013 2012 2011 2010 2009 2008 2005 2004

All Journal Article Presentation Patent

  • [Journal Article] Functionally cloned pdrM from Streptococcus pneumoniae encodes a Na+ coupled multidrug efflux pump2013

    • Author(s)
      Hashimoto K, Ogawa W, Nishioka T, Tsuchiya T, Kuroda T
    • Journal Title

      PLoS One

      Volume: 8(3)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Journal Article] Functionally cloned pdrM from Streptococcus pneumoniae encodes a Na+ coupled multidrug efflux pump.2013

    • Author(s)
      Hashimoto K, Ogawa W, Nishioka T, Tsuchiya T, Kuroda T
    • Journal Title

      PLoS One

      Volume: 8(3) Issue: 3 Pages: e59525-e59525

    • DOI

      10.1371/journal.pone.0059525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Journal Article] Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae.2012

    • Author(s)
      Ogawa W, Onishi M, Ni R, Tsuchiya T, Kuroda T
    • Journal Title

      Gene

      Volume: 498(2) Issue: 2 Pages: 177-182

    • DOI

      10.1016/j.gene.2012.02.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Journal Article] Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae2012

    • Author(s)
      Ogawa W, Onishi M, Ni R, Tsuchiya T, Kuroda T
    • Journal Title

      Gene

      Volume: 498(2) Pages: 177-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Journal Article] Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents2011

    • Author(s)
      Hossion AM, Zamami y Kandahary RK, Tsuchiya T, Ogawa W, Iwado A, Sasaki K
    • Journal Title

      J Med Chem

      Volume: 54 Issue: 11 Pages: 3686-3703

    • DOI

      10.1021/jm200010x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Journal Article] Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents.2010

    • Author(s)
      Hossion, A.M., N.Otsuka, R.K.Kandahary, T.Tsuchiya, W.Ogawa, A.Iwado, Y.Zamami, K.Sasaki.
    • Journal Title

      Bioorg.Med.Chem.Lett. 20

      Pages: 5349-5352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents.2010

    • Author(s)
      Hossion AM, Otsuka N, Kandahary RK, Tsuchiya T, Ogawa W, Iwado A, Zamami Y, Sasaki K.
    • Journal Title

      Bioorg Med Chem Lett.

      Volume: 20 Pages: 5349-5352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Journal Article] Gene cloning and characterization of EfmA, a multidrug efflux pump, from Enterococcus faecium.2009

    • Author(s)
      Nishioka, T., W.Ogawa, T.Kuroda, T.Katsu, T.Tsuchiya.
    • Journal Title

      Biol.Pharm.Bull. 32

      Pages: 483-488

    • NAID

      110007122697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa.2009

    • Author(s)
      Mima, T., N.Kohira, Y.Li, H.Sekiya, W.Ogawa, T.Kuroda, T.Tsuchiya.
    • Journal Title

      Microbiology 155

      Pages: 3509-3517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Effect of natural polyphenols on methicillin-resistant Staphylococcus aureus in relation to their chemical and physical properties.2009

    • Author(s)
      Hatano, T., M.Kusuda, M.Tsugawa, S.Taniguchi, T.Tsuchiya, T.Yoshida.
    • Journal Title

      Phytochem.Res.

      Pages: 31-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Synergistic effect of kaempferol glycosides purified from Laurus nobilis and fluoroquinolones on methicillin-resistant Staphylococcus aureus.2009

    • Author(s)
      Liu, M.H., N.Otsuka, K.Noyori, S.Shiota, W.Ogawa, T.Kuroda, T.Hatano, T.Tsuchiya.
    • Journal Title

      Biol.Pharm.Bull. 32

      Pages: 489-492

    • NAID

      110007122695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Enhancement of antibacterial effects of epigallocatechin gallate, using ascorbic acid.2008

    • Author(s)
      Hatano, T., M.Tsugawa, M.Kusuda, S.Taniguchi, T.Yoshida, S.Shiota, T.Tsuchiya.
    • Journal Title

      Phytochemistry 69

      Pages: 3111-3116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Anti-methicillin resistant Staphylococcus aureus (MRSA) compounds isolated from Laurus nobilis.2008

    • Author(s)
      Otsuka, N., M.H.Liu, S.Shiota, W.Ogawa, T.Kuroda, T.Hatano, T.Tsuchiya.
    • Journal Title

      Biol.Pharm.Bull. 31

      Pages: 1794-1797

    • NAID

      110006878971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Functional gene cloning and characterization of the SsmE multidrug efflux pump from Serratia marcescens.2008

    • Author(s)
      Minato, Y., F.Shahcheraghi, W.Ogawa, T.Kuroda, T.Tsuchiya.
    • Journal Title

      Biol.Pharm.Bull. 31

      Pages: 516-519

    • NAID

      110006623085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Journal Article] Identification of essential amino acid residues of the NorM Na+/multidrug antipoter in Vibrio parahaemolyticus2005

    • Author(s)
      Masato Otsuka, Tomofusa Tsuchiya 外
    • Journal Title

      J.Bacteriol. 187

      Pages: 1552-1558

    • Data Source
      KAKENHI-PROJECT-16390131
  • [Journal Article] Remarkable synergies between baicalein and tetracycline, and baicaleir and β-lactams against methicillin-resistant Staphylococcus aureus2005

    • Author(s)
      Mai Fujita, Tomofusa Tsuchiya 外
    • Journal Title

      Microbiol.Immunol. (In press)

    • Data Source
      KAKENHI-PROJECT-16390131
  • [Journal Article] Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of β-lactams against methicillin-resistant Staphylococcus aureus2004

    • Author(s)
      Sumiko Shiota, Tomofusa Tsuchiya 外
    • Journal Title

      Microbiol.Immunol. 48

      Pages: 67-73

    • NAID

      50000379722

    • Data Source
      KAKENHI-PROJECT-16390131
  • [Journal Article] A major Li^+ extrusion system NhaB of Pseudomonas aeruginosa : Comparison with the major Na^+ extrusion system NhaP2004

    • Author(s)
      Teruo Kuroda, Tomofusa Tsuchiya 外
    • Journal Title

      Microbiol.Immunol. 48

      Pages: 243-250

    • NAID

      10012840106

    • Data Source
      KAKENHI-PROJECT-16390131
  • [Patent] バイオフィルム形成阻害剤2010

    • Inventor(s)
      土屋友房、塩田澄子
    • Industrial Property Rights Holder
      土屋友房、塩田澄子
    • Filing Date
      2010-05-04
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Patent] バイオフィルム形成阻害剤2009

    • Inventor(s)
      土屋友房、塩田澄子
    • Industrial Property Rights Holder
      土屋友房、塩田澄子
    • Filing Date
      2009-04-13
    • Data Source
      KAKENHI-PROJECT-20590120
  • [Presentation] 多剤耐性緑膿菌の出現と抗菌薬曝露の関係2013

    • Author(s)
      藤岡 孝浩,保田 菜美,土屋 友房,小川 和加野,黒田 照夫
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Serratia marcescensにおける新規消毒薬耐性因子の解析2013

    • Author(s)
      峠雄太,小川 和加野,土屋 友房,後藤 直正,黒田 照夫
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Serratia marcescensの消毒薬クロルヘキシジンに対する耐性機構の解析2012

    • Author(s)
      芳賀仁美、峠雄太、朝熊弘樹、小川和加野、後藤直正、土屋友房、黒田照夫
    • Organizer
      第24回微生物シンポジウム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌のMATE型多剤排出ポンプKrtM、DinF、YeeOの解析2012

    • Author(s)
      堂段駿太、高桂鳳、岸野孝則、大西元康、土屋友房、黒田照夫、小川和加野
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Isolation and analysis of Klebsiella pneumoniae ATCC10031 multidrug resistant mutants2012

    • Author(s)
      W. Ogawa, R. Ni, M. Mizusawa, M. Onishi, R. Kitagawa, T. Tsuchiya, and T. Kuroda
    • Organizer
      II International Conference on Antimicrobial Research
    • Place of Presentation
      Lisbon, Portugal
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 大腸菌Giant Protoplastにおける新規大量発現系の構築2012

    • Author(s)
      三上太郎、中村浩二、村井美知子、谷聖人、小川和加野、土屋友房、矢部勇、黒田照夫
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 多剤耐性肺炎桿菌 Oxa128株における RND型排出ポンプOqxABの解析2012

    • Author(s)
      北川良子,倪蕊〓,大西元康,土屋友房,小川和加野,黒田照夫
    • Organizer
      第65回 日本細菌学会中国・四国支部総会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 多剤耐性緑膿菌の分離及びその耐性メカニズムの解析2012

    • Author(s)
      保田菜美、藤岡孝浩、藤田智子、土屋友房、小川和加野、黒田照夫
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 多剤耐性緑膿菌の分離及びその耐性メカニズムの解析2012

    • Author(s)
      保田菜美、藤岡孝浩、藤田智子、土屋友房、小川和加野 、黒田照夫
    • Organizer
      第65回日本細菌学会中国・四国支部総会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌のMATE型多剤排出ポンプKrtM、DinF2012

    • Author(s)
      堂段駿太、高桂鳳、岸野孝則、大西元康、土屋友房、黒田照夫、小川和加野
    • Organizer
      YeeOの解析(第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] NA^+ TOLERANCE MECHANISM IN HALOPHILIC VIBRIO PAEAHAEMOLYTICUS2011

    • Author(s)
      Teruo Kuroda, Yu Nagira, KiyohitoTani', Seiji Kojim, Mari Okuno, Makoto Miyazawa, Wakano Ogawa, Tomofusa Tsuchiya
    • Organizer
      IUMS 2011
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Functional study of RND-type multidrug efflux pump KexD from Klebsiella pneumoniae2011

    • Author(s)
      Wakano Ogawa, Motoyasu Onishi, Rui-ting Ni, Teruo Kuroda, and Tomofusa Tsuchiya
    • Organizer
      IUMS2011
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] ブドウ球菌によるバイオフィルム形成能および安全性に対する高分子膜中の各種テルペノイドの影響について2011

    • Author(s)
      塩田澄子、山田陽一、大塚智恵、内田多恵子、小川和加野、黒田照夫、土屋友房
    • Organizer
      第56回ブドウ球菌研究会
    • Place of Presentation
      高知
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] ブドウ球菌属によるバイオフィルム産生を抑制する物質2011

    • Author(s)
      塩田澄子、大塚智恵、内田多恵子、山田陽一、小川和加野、黒田照夫、土屋友房
    • Organizer
      第23回微生物シンポジウム
    • Place of Presentation
      銚子、千葉
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] CLONING AND CHAEACTERIZATION OF WMA, A MULTIDRUG EFFLUX PUMP FROM VIBRIO VULNIFICUS2011

    • Author(s)
      Eun-Woo Lee, Tae-Hwan Byun, Do-Kyun Kim, Young-Mog Kim, Myung-Suk Lee, Byung-Woo Kim, Wakano Ogawa, Teruo Kuroda, Tomofusa Tsuchiya
    • Organizer
      IUMS 2011
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌の多剤耐性変異株の分離とその解析2011

    • Author(s)
      小川和加野、水澤実名子、Ni Ruiting、大西元康、土屋友房、黒田照夫
    • Organizer
      第33回生体膜と薬物の総合作用シンポジウム
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Functional study of RND-type multidrug efflux pump KexD from Klebsiella pneumoniae2011

    • Author(s)
      Wakano Ogawa, Motoyasu Onishi, Rui-ting Ni, Teruo Kuroda, Tomofusa Tsuchiya
    • Organizer
      IUMS2011
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌のRND型多剤排出ポンプAcrABの性質2010

    • Author(s)
      水澤実名子, 大西元康, 倪蕊〓, 小川和加野, 黒田照夫, 土屋友房
    • Organizer
      第63回日本細菌学会中国・四国支部総会
    • Place of Presentation
      愛媛県松山市
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌のRND型多剤排出ポンプAcrABの性質2010

    • Author(s)
      水澤実名子, 大西元康, 倪蕊〓, 小川和加野, 黒田照夫, 土屋友房
    • Organizer
      第63回日本細菌学会中国・四国支部総会
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Novel 2",3",4",6"-o-substituted quercetin-3-o-galactosides and glucosides analogous as potent anti-MRSA and anti-VRE agents : Design, synthesis, sar and in-vitro assessment2010

    • Author(s)
      Abugafar M.L.Hossion, Rafiya K.Kandahary, Tomofusa Tsuchiya, Wakano Ogawa, Yoshito Zamami, Kenji Sasakia
    • Organizer
      XXIVth European Colloquium on Heterocyclic Chemistry (ECHC-2010)
    • Place of Presentation
      Vienna University of Technology Vienna (Austria)
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] Serratia marcescensの消毒薬耐性系の解析2010

    • Author(s)
      朝熊弘樹、芳賀仁美、小川和加野, 黒田照夫、後藤直正、土屋友房
    • Organizer
      XXIVth European Colloquium on Heterocyclic Chemistry (ECHC-2010)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 腸炎ビブリオのNa+耐性機構2010

    • Author(s)
      柳樂優, 谷聖人, 宮澤誠, 小川和加野, 土屋友房, 黒田照夫
    • Organizer
      第44回腸炎ビブリオシンポジウム
    • Place of Presentation
      秋田
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] ブドウ球菌のバイオフィルム形成に対するAbietic acidと関連物質の影響2010

    • Author(s)
      新谷真代、森江未希、野依久美子、黒田照夫、小川和加野、塩田澄子、土屋友房
    • Organizer
      第55回日本ブドウ球菌研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 腸炎ビブリオのNa+耐性に対するNa+/H+アンチポーターと呼吸鎖Na+ポンプの重要性2010

    • Author(s)
      柳樂優, 谷聖人, 宮澤誠, 小川和加野, 土屋友房, 黒田照夫
    • Organizer
      第22回微生物シンポジウム
    • Place of Presentation
      愛媛県松山市
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌の多剤排出ポンプと多剤耐性化2010

    • Author(s)
      小川和加野、大西元康、Ni RuiTing、水澤実名子、岸野孝則、高 桂鳳、黒田照夫、土屋友房
    • Organizer
      第32回生体膜と薬物の総合作用シンポジウム
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-22590064
  • [Presentation] 肺炎桿菌の多剤排出ポンプと多剤耐性化2009

    • Author(s)
      小川和加野、大西元康、Ni RuiTing、水澤実名子、岸野孝則、高桂鳳、黒田照夫、土屋友房
    • Organizer
      第32回生体膜と薬物の総合作用シンポジウム
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-22590064
  • 1.  KURODA Teruo (80304327)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 30 results
  • 2.  TSUDA Masaaki (80132736)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  SHIMAMOTO Tadashi (90187443)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  向畑 恭男 (10028110)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  今栄 康雄 (70022712)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  山中 健生 (40028113)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  吉田 賢右 (90049073)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  WILSON Thomas H.
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  MASUDA Kazuhumi (00243486)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MIO Mitsunobu (70190600)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KURODA Masayuki (00253005)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  MIZUSHIMA Tohru (00264060)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  月原 冨武 (00032277)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  徳田 元 (40125943)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  OGAWA Wakano (90397878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 32 results
  • 16.  OKADA Yasunobu (10025661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MARUMO Fumiaki (00050443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  UEDA Kazumitsu (10151789)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  IMAI Masashi (40049010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAKEGUCHI Noriaki (00019126)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NEGISHI Kazuo (70116490)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KOBAYASHI Sakae (90212654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  ONO Katsuhiko (30152523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KAWAMURA Koki (40048286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  前島 正義 (80181577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  山口 明人 (60114336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  野間 昭典 (00132738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  清野 進 (80236067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  笠原 道弘 (40010102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  乾 賢一 (70034030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  北里 宏 (20079700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  富田 由妃 (10243487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  MALONEY Peter C
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  KONINGS Wil, N
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  THOMAS H.Wil
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  PETER C. Mal
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  KONINGS Wil
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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