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KOIKE Kichiko  小池 吉子

ORCIDConnect your ORCID iD *help
Researcher Number 80039619
Affiliation (based on the past Project Information) *help 1994: Nagasaki University Sch.of Med.Associ.Prof., 医学部, 助教授
1986 – 1992: 長崎大学, 医学部, 助教授
1986: 長崎大, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / 代謝生物化学
Except Principal Investigator
代謝生物化学 / Pathological medical chemistry
Keywords
Principal Investigator
ピルビン酸脱水素酵素 / 塩基配列 / クローニング / 発現調節 / 遺伝子 / TATA box / CAAT box / 転写開始点 / Colony Hybridization / <lambda>gt11 Expression Screening … More / Thiamin Pyrophosphate-dependent Enzyme / 遺伝子(cDNA) / 攻α,β家兎抗体 / 【α_2】【β_2】構造 / α, βゲノムDNA / α, βmRNA / アミノ酸配列 / α, βcDNA / α, βサブユニット / chromosomal localization / transcription start point / coenzyme TPP / intron / exon / gene / 2-oxoglutarate dehydrogenase / ヒト / 染色体局在 / 補酵素TPP / イントロン / エクソン / 2-オキソグルタル酸脱水素酵素 / Point mutation / PCR-amplification / Deficiency / Expression / Gene / alpha and beta subunits / Pyruvate dehydrogenase / 変異(欠損症)遺伝子 / βーサブユニット遺伝子 / αーサブユニット遺伝子 / ヒトピルビン酸脱水素酵素 / 点変異 / PCR増幅 / 欠損症 / α,βサブユニット / Pyruvate dehydrogenase deficiency / Transcription start point / PDHbeta gene / PDHalpha gene / Pyruvate dehydrogenase (PDH) / ピルビン酸脱水素酵素欠損症 / βサブユニット / αサブユニット … More
Except Principal Investigator
cDNA / mRNA / 塩基配列 / ピルビン酸脱水素酵素 / nucleotide sequences / PDHbeta gene / PDHalpha gene / biosynthesis / PDHalpha, beta mRNAs / PDHalpha, beta cDNAs / alpha_2beta_2 subunit structure / pyruvate dehydrogenase (PDH) / 機能発現 / 構造形成 / 生合成 / 遺伝子 / ヒト / Amino Acid Sequences / Nucleotide Sequence / Cloning / Dihydrolipoamide Acyl-transferase / ミトコンドリア / 前駆体の局在化 / アミノ酸配列 / クローニング / リポ酸アシル基転移酵素 / 点突然変異プライマー / リン酸化部位 / α, βcDNA / α, βサブユニット / リン酸化共有修飾 / クエン酸回路酵素 / トランスフェラ-ゼ / エピト-プ領域 / ジヒドロリポアミドスクシニル / ジヒドロリポアミドアセチルトランスフェラ-ゼ / 自己免疫疾患 / 原発性胆汁性肝硬変症 Less
  • Research Projects

    (8 results)
  • Co-Researchers

    (5 People)
  •  Structure and expression of the human 2-oxoglutarate dehydrogenase genePrincipal Investigator

    • Principal Investigator
      KOIKE Kichiko, 小池 吉子
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagasaki University
  •  Pyruvate Dehydrogenase Gene: Regulation of its Expression and Identification of Mutation in the PCR-amplified Exon Segments from the Patient with Fatal DeficiencyPrincipal Investigator

    • Principal Investigator
      KOIKE Kichiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Nagasaki University
  •  原発性胆汁性肝硬変症の発症機序解析と簡易診断法の開発

    • Principal Investigator
      KOIKE Masahiko
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagasaki University
  •  Structure, Expression and Pathogenesis of Human Pyruvate Dehydrogenase GenePrincipal Investigator

    • Principal Investigator
      KOIKE Kichiko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagasaki University
  •  Genetic control of biosynthesis, structural assembly and activity expression of eukaryotic pyruvate dehydrogenase

    • Principal Investigator
      KOIKE Masahiko
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Nagasaki University
  •  クエン酸回路酵素のリン酸化共有修飾による活性制御とATP産生応答の遺伝子調節

    • Principal Investigator
      小池 正彦
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagasaki University
  •  Primary and Gene Structures and Defect of Pyruvate Dehydrogenase (Thiamin pyrophosphate enzyme)Principal Investigator

    • Principal Investigator
      KOIKE Kichiko
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagasaki University
  •  Cloning and expression of dihydrolipoamide acyl-transferase gene and localization of its product in mitochondria

    • Principal Investigator
      KOIKE Masahiko
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Nagasaki University
  • 1.  KOIKE Masahiko (10039521)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  URATA Yoshishige (30185087)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  YANAGITA Yutaka (80191162)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  GOTO Sinji (50186889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MATSUO Sachiko (80039916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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