KOIKE Kichiko 小池吉子

Researcher Number	80039619
Affiliation (based on the past Project Information) *help	1994: Nagasaki University Sch.of Med.Associ.Prof., 医学部, 助教授 1986 – 1992: 長崎大学, 医学部, 助教授 1986: 長崎大, 医学部, 助教授
Review Section/Research Field	Principal Investigator Pathological medical chemistry / 代謝生物化学 Except Principal Investigator 代謝生物化学 / Pathological medical chemistry
Keywords	Principal Investigator ピルビン酸脱水素酵素 / 転写開始点 / CAAT box / TATA box / 遺伝子 / 発現調節 / クローニング / 塩基配列 / αサブユニット / βサブユニット … More / ピルビン酸脱水素酵素欠損症 / Pyruvate dehydrogenase (PDH) / PDHalpha gene / PDHbeta gene / Transcription start point / Pyruvate dehydrogenase deficiency / α,βサブユニット / 欠損症 / PCR増幅 / 点変異 / ヒトピルビン酸脱水素酵素 / αーサブユニット遺伝子 / βーサブユニット遺伝子 / 変異(欠損症)遺伝子 / Pyruvate dehydrogenase / alpha and beta subunits / Gene / Expression / Deficiency / PCR-amplification / Point mutation / 2-オキソグルタル酸脱水素酵素 / エクソン / イントロン / 補酵素TPP / 染色体局在 / ヒト / 2-oxoglutarate dehydrogenase / gene / exon / intron / coenzyme TPP / transcription start point / chromosomal localization / α, βサブユニット / α, βcDNA / アミノ酸配列 / α, βmRNA / α, βゲノムDNA / 【α_2】【β_2】構造 / 攻α,β家兎抗体 / 遺伝子(cDNA) / Thiamin Pyrophosphate-dependent Enzyme / <lambda>gt11 Expression Screening / Colony Hybridization … More Except Principal Investigator ピルビン酸脱水素酵素 / 塩基配列 / mRNA / cDNA / 原発性胆汁性肝硬変症 / 自己免疫疾患 / ジヒドロリポアミドアセチルトランスフェラ-ゼ / ジヒドロリポアミドスクシニル / エピト-プ領域 / トランスフェラ-ゼ / クエン酸回路酵素 / リン酸化共有修飾 / α, βサブユニット / α, βcDNA / リン酸化部位 / 点突然変異プライマー / リポ酸アシル基転移酵素 / クローニング / アミノ酸配列 / 前駆体の局在化 / ミトコンドリア / Dihydrolipoamide Acyl-transferase / Cloning / Nucleotide Sequence / Amino Acid Sequences / ヒト / 遺伝子 / 生合成 / 構造形成 / 機能発現 / pyruvate dehydrogenase (PDH) / alpha_2beta_2 subunit structure / PDHalpha, beta cDNAs / PDHalpha, beta mRNAs / biosynthesis / PDHalpha gene / PDHbeta gene / nucleotide sequences Less

Research Projects
(8 results)
Co-Researchers
(5 People)

Structure and expression of the human 2-oxoglutarate dehydrogenase genePrincipal Investigator
- Principal Investigator
  
  KOIKE Kichiko, 小池吉子
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagasaki University
Pyruvate Dehydrogenase Gene: Regulation of its Expression and Identification of Mutation in the PCR-amplified Exon Segments from the Patient with Fatal DeficiencyPrincipal Investigator
- Principal Investigator
  
  KOIKE Kichiko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Nagasaki University
原発性胆汁性肝硬変症の発症機序解析と簡易診断法の開発
- Principal Investigator
  
  KOIKE Masahiko
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagasaki University
Structure, Expression and Pathogenesis of Human Pyruvate Dehydrogenase GenePrincipal Investigator
- Principal Investigator
  
  KOIKE Kichiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagasaki University
Genetic control of biosynthesis, structural assembly and activity expression of eukaryotic pyruvate dehydrogenase
- Principal Investigator
  
  KOIKE Masahiko
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Nagasaki University
クエン酸回路酵素のリン酸化共有修飾による活性制御とATP産生応答の遺伝子調節
- Principal Investigator
  
  小池正彦
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagasaki University
Primary and Gene Structures and Defect of Pyruvate Dehydrogenase (Thiamin pyrophosphate enzyme)Principal Investigator
- Principal Investigator
  
  KOIKE Kichiko
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagasaki University
Cloning and expression of dihydrolipoamide acyl-transferase gene and localization of its product in mitochondria
- Principal Investigator
  
  KOIKE Masahiko
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  Nagasaki University

1. KOIKE Masahiko (10039521)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. URATA Yoshishige (30185087)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. YANAGITA Yutaka (80191162)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. GOTO Sinji (50186889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUO Sachiko (80039916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOIKE Kichiko 小池 吉子

Research Projects

Co-Researchers

Structure and expression of the human 2-oxoglutarate dehydrogenase genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pyruvate Dehydrogenase Gene: Regulation of its Expression and Identification of Mutation in the PCR-amplified Exon Segments from the Patient with Fatal DeficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

原発性胆汁性肝硬変症の発症機序解析と簡易診断法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure, Expression and Pathogenesis of Human Pyruvate Dehydrogenase GenePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic control of biosynthesis, structural assembly and activity expression of eukaryotic pyruvate dehydrogenase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クエン酸回路酵素のリン酸化共有修飾による活性制御とATP産生応答の遺伝子調節

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Primary and Gene Structures and Defect of Pyruvate Dehydrogenase (Thiamin pyrophosphate enzyme)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cloning and expression of dihydrolipoamide acyl-transferase gene and localization of its product in mitochondria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

KOIKE Kichiko 小池吉子