SUGIMURA Kazuhisa 杉村和久

… Alternative Names

杉村和久スギムラカズヒサ

SUGIMRUA Kazuhisa 杉村和久

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Researcher Number	80127240
Other IDs
External Links
Affiliation (Current)	2025: 鹿児島大学, 医歯学総合研究科, 客員教授
Affiliation (based on the past Project Information) *help	2011: 鹿児島大学, 理工学研究科, 教授 2009 – 2011: Kagoshima University, 理工学研究科(工学系), 教授 1998 – 2007: 鹿児島大学, 工学部, 教授 1996: 鹿児島大学, 工学部, 教授 1992 – 1994: 鹿児島大学, 工学部, 教授 … More 1991: 北海道大学, 免疫科学研究所, 助教授 1988 – 1991: 北海道大学, 免疫科学研究所・化学部門, 助教授 1990: Hokkaido Univ., Inst. Immunol. Sci. Associate Professor, 助教授 1989: 北海道大学, 免疫科学研究所, 助教授 1988 – 1989: 北海道大学, 免疫科学研究所化学部門, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Living organism molecular science / Experimental pathology / Immunology / 広領域 Except Principal Investigator Drug development chemistry / 内科学一般 / Immunology / 食の安全 / 医薬分子機能学 / Biological Sciences / Molecular biology / Natural disaster science
Keywords	Principal Investigator ファージライブラリー / MCP-1 / ヒト抗体 / IL-6 / 分子設計 / scFv / ペプチドミミック / エイズ / CCR5 / ペプチドミメティックス … More / サイトカイン / マイコプラズマ / 遺伝子発現 / ファージライブラリ / 免疫制御 / 感染防御 / IL-5 / インヒビター / ワクチン / 癌転移 / 尿素サイクル / アルギニノコハク酸シンテタ-ゼ / LBIF / Hyperactive B Lymphocytes / MRL Mice / Autoimmune Disease / Arginine Metabolism / Arginine Deiminase Gene / Mycoplasma Arginine / Lymphocyte Blastogenesis Inhibitory Factor / 増殖抑制 / U937 / IL-2レセプター / 細胞周期 / 細胞増殖 / 細胞内情報伝達機構 / LBIF遺伝子 / 過活性化B細胞 / MRLマウス / 自己免疫疾患 / アルギニン代謝 / アルギニンデイミナ-ゼ遺伝子 / リンパ球増殖阻止因子 / )Mycoplasma arginini / PHAGE LIBRARY / PEPTIDE ANTAGONIST / ANTIBODY ENGINEERING / MOLECULAR TARGETING / ANTIBODY DRUG / HUMAN ANTIBODY / ペプチド / ミミック / 抗体 / ヒト / ScFv / ペプチドアンタゴニスト / 抗体エンジニアリング / 分子標的医療 / 抗体医薬 / Molecular design / Inhibitor / Human antibody / Peptide mimic / Phage library / IgE / TNFα / モノクロナル抗体 / オリゴマー / J20 / 受動免疫 / Aβ42 / TLR9 / MyD88 / アミロイドベーター / ミミックペプチド / 自然免疫 / M13ファージ / アルツハイマー認知症 / エントリーインヒビター / 感染 / エントリーインフビター / HIV-1 / ケモカイン / T細胞 / コスティムユラ / 免疫応答 / CTLA4 / 遺伝子クローニング / Mycoplasma arginini / 酵素 / 分子生物学 / アルギノコハク酸シンテターゼ / PCR法 / 診断法 / 急性転化 / 慢性骨髄性白血病 / 免疫抑制因子 / アルギニンディミナ-ゼ / AIDS / 末梢血リンパ球 / PCR / 白血病 / 過活性化Bリンパ球 / Lーアルギニン代謝 / BXSB / l / MRL / SLE / 自己免疫 / 細胞増殖阻止因子 / 癌 … More Except Principal Investigator ワクチン / 抗体医薬 / ヒト抗体 / T細胞 / IL-8 / THP-1 / HMGB-1 / SOCS-1 / ファージディスプレイ / 遺伝子治療 / 補助刺激分子 / バイオコンジュゲート / ターゲッティング / Drug delivery system / Carboxymethyl-chitin (CM-chitin) / Prevention of Cancer Metastasis / Sulfated Carboxymethyl Chitin (SCM-chitin) / Adjuvant Activity / 70% Deacetylated chitin (DAC-70) / スルホン化キトサン / スルホン化キチン / 癌転移抑制 / 免疫増強活性 / 硫酸化キトサン / 硫酸化キチン / ドラッグデリバリ-システム / カルボキシメチルキチン(CMーキチン) / 癌転移阻止 / 硫酸化カルボキシメチルキチン(SCMーキチン) / アジュバント活性 / 70%脱アセルチルキチン(DACー70) / inflammation / sepsis / human antibody phage library / ペプチド / 阻害剤 / 炎症 / 敗血症 / ヒト抗体ファージライブラリ / Neurodegenerative disorders / Diagnosis / Food / Conformation / Antibody engineering / Prion / Human antibody / Phage display / 脳神経疾患 / 抗体エンジリアリング / 脳神経変性疾患 / 診断 / 食品 / コンフォメーション / 抗体エンジニアリング / プリオン / gene therapy / antibody medicine / gene expression / costimulatory molecule / Sendai virus vector / immune response control / Antibody phage library / 免疫抑制 / 遺伝子発現 / 抗体ファージライブラリ / 免疫制御 / センダイウイルスベクター / negative regulator / adenoviral vector / vascular endothelial growth factor / humanized anti-IL-6 receptor antibody / interleukin-6 / rheumatoid arthritis / SSI-1 / アデノウイルスベクター / 負の調節因子 / アデノウイルス / 血管内皮増殖因子(VEGF) / ヒト化抗IL-6レセプター抗体 / インターロイキン6(IL-6) / 関節リウマチ / targeting / antagonist / T cell / antigen presenting cell / vaccine / phage library / human antibody / Costimulatory molecules / DNAワクチン / 免疫反応の制御 / 阻害抗体 / ワクチン開発 / 拒絶反応抑制 / アレルギー / T細胞増殖 / 単鎖Fv抗体 / 免疫応答制御 / アンタゴニスト / 抗原提示細胞 / ファージライブラリ / IL-6阻害 / ペプチド阻害剤 / 小分子ヒト抗体 / single chain fragment variant / ファージライブラリー / 癌増殖抑制 / 二次性アミロイドーシス / メタプロテアーゼ / 血管新生 / 滑膜増殖 / ヒト型抗IL-6レセプター抗体 / RA / インターロイキン6 / 抗体産生 / CTLA4(CD152) / 免疫応答 / 融合蛋白質 / ナノスフェア / CTLA4 / CD80 / 免疫増強 / 顔面 / 頭部 / ノックアウトマウス / 脊椎動物 / グ-スコイド / ホメオボックス / 災害新技術 / 公害測定 / 火山災害 / 自然災害 Less

Amyloid beta-42-mimotope displaying M13 bacteriophage for vaccine vehicle of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  SUGIMURA Kazuhisa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kagoshima University
Basic studies for development of inhibitor to target nuclear inflammatory cytokine related with sepsis
- Principal Investigator
  
  ITO Yuji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kagoshima University
Fundamental researches for antibody medicine development by the virus vector aiming at control of the immune response
- Principal Investigator
  
  ITO Yuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kagoshima University
Prion-conformation-specific human antibodies established from phage display library.
- Principal Investigator
  
  HASHIGUCHI Shuhei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食の安全
- Research Institution
  Kagoshima University
ファージライブラリーを用いたIL-6阻害ヒト抗体および低分子癌抑制分子の開発
- Principal Investigator
  
  吉崎和幸
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Study on molecular targeting using phage dispky libraryPrincipal Investigator
- Principal Investigator
  
  SUGIMURA Kazuhisa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kagoshima University
Research of molecular biology and gene therapy for Rheumatoid arthritis by regulation of IL-6 signal transduction
- Principal Investigator
  
  NISHIMOTO Norihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
エイズ感染阻子分子の分子設計法の基礎研究Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
ファージディスプレイライブラリーを用いた感染防御と免疫制御法の開発Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
Isolation of human antibodies targeting to immunocytes from phage library and regulation of immune response
- Principal Investigator
  
  ITO Yuji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kagoshima University
エイズ感染阻止分子の分子設計法の基礎研究Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
免疫制御分子の機能性ドメインミミックの分子設計と免疫制御Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
IL-6シグナル制御による慢性関節リウマチの分子・遺伝子治療の研究
- Principal Investigator
  
  NISHIMOTO Norihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Osaka University
免疫細胞への標的機能を持つバイオコンジュゲートによる免疫制御
- Principal Investigator
  
  伊東祐二
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kagoshima University
エイズワクチンの活性強化分子の分子設計法の基礎研究Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
Molecular design of functional domain-mimics of receptors and ligandsPrincipal Investigator
- Principal Investigator
  
  SUGIMURA Kazuhisa
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Kagoshima University
免疫細胞への標的機能を持つバイオコンジュゲートによる免疫制御
- Principal Investigator
  
  ITO Yuji
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kagoshima University
エイズワクチンの活性強化分子の分子設計法の基礎研究Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
グ-スコイド遺伝子変異マウスを用いた顔面-頭部形成機構の解析
- Principal Investigator
  
  山田源
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kagoshima University
超電導量子干渉磁束計を用いた火山灰の肺内蓄積量の測定及び生体への影響
- Principal Investigator
  
  大串哲彌
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Natural disaster science
- Research Institution
  Kagoshima University
In vivoでがん転移を促進するマイコプラズマ分子の構造と機能Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kagoshima University
In vivoで癌転移を促進するマイコプラズマ分子の構造と機能の研究Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kagoshima University
慢性骨髄白血病の急性転化の分子生物学的診断と予知法の開発Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
成人T白血病細胞株に認められたアルギニノコハク酸合成酵素遺伝子発現の異常亢進;ーその白血病診断マ-カ-としての意義ーPrincipal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
HIVのTリンパ球殺傷効果を増幅するマイコプラズマ感染の意義Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
細胞増殖阻止因子を用いた全身性自己免疫疾患モデルマウスの病因の解析Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
細胞増殖を阻止する免疫制御因子の作用機序と分子構造の解析Principal Investigator
- Principal Investigator
  
  杉村和久
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
Molecular Structure and Function of a Novel Immunoinhibitory Protein Institute of Immunological SciencePrincipal Investigator
- Principal Investigator
  
  SUGIMURA Kazuhisa
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Application of Chitin Derivatives to the Biomedical Materials
- Principal Investigator
  
  AZUMA Ichiro
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University

All 2012 2011 2010 2009 2008 2005 2004 2003 2002 2001

All Journal Article Presentation Patent

[Journal Article] Direct evidence of generation and accumulation ofβ-sheet-rich prion protein in scrapie-infected neuroblastoma cells with a human IgG1 antibody specific for the b-form prion protein2012
- Author(s)
  Toshiya Kubota, Yuta Hamazoe, Shuhei Hashiguchi, Daisuke Ishibashi, Kazuyuki Akasaka, Noriyuki Nishida, Shigeru Katamine, Suehiro Sakaguchi, Ryota Kuroki, Toshihiro Nakashima, and Kazuhisa Sugimura
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 14023-14039
- URL
  http://www.jbc.org/content/287/17/14023.full
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] Direct evidence of generation and accumulation of β-sheet-rich prion protein in scrapie-infected neuroblastoma cells with a human IgG1 antibody specific for the b-form prion protein2012
- Author(s)
  Toshiya Kubota, Yuta Hamazoe, Shuhei Hashiguchi, Daisuke Ishibashi, Kazuyuki Akasaka, Noriyuki Nishida, Shigeru Katamine, Suehiro Sakaguchi, Ryota Kuroki, Toshihiro Nakashima, Kazuhisa Sugimura
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 287 Pages: 14023-14039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] A mimotope peptide of Aβ42 fibril-specific antibodies with Aβ42 fibrillation inhibitory activity induces anti-Aβ42 conformer antibody response by a displayed form on an M13 phage in mice2011
- Author(s)
  Koichi Tanaka, Masaaki Nishimura, Yuya Yamaguchi, Shuhei Hashiguchi, Sho Takiguchi, Makoto Yamaguchi, Haruna Tahara, Takuma Gotanda, Risa Abe, Yuji Ito, Kazuhisa Sugimura
- Journal Title
  
  J.Neuroimmunology
  
  Volume: 236 Pages: 27-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] A mimotope peptide of Aβ42 fibril-specific antibodies with Aβ42 fibrillation inhibitory activity induces anti-Aβ42 conformer antibody response by a displayed form on an M13 phage in mice2011
- Author(s)
  Koichi Tanaka, Masaaki Nishimura, Yuya Yamaguchi, Shuhei Hashiguchi, Sho Takiguchi, Makoto Yamaguchi, Haruna Tahara, Takuma Gotanda, Risa Abe, Yuji Ito, Kazuhisa Sugimura
- Journal Title
  
  J. Neuroimmunology
  
  Volume: 236 Pages: 27-38
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21641049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] Characterization of Human Single-Chain Antibodies Against Highly Pathogenic Avian Influenza H5N1 Viruses : Mimotope and Neutralizing Activity.2010
- Author(s)
  JiuPian Yang, Reiko Yoshida, Yuji Ito, Yuki Kariya, Xu Zhang, Shuhei Hashiguchi, Toshihiro Nakashima, Yasuo Suda, Ayato Takada, Kazuhisa Sugimura.
- Journal Title
  
  J.Biochem.
  
  Volume: 148 Pages: 504-515
- NAID
  10027879101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphyloccus aureus proteins.2010
- Author(s)
  May Kuroda-Morimoto, Hidehisa Tanaka, Nobuki Hayashi, Masakiyo Nakahira, Tasutomo Imai, Michiko Imamura, Koubun Yasuda, Shizue Yumikura-Futatsugi, Kiyoshi Matsui, Toshihiro Nakashima, Kazuhisa Sugimura, Hiroko Tsutsui, Hajime Sano, Keiji Nakanishi
- Journal Title
  
  Int.Immunol.
  
  Volume: 22 Pages: 561-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] ファージディスプレイとBeyond antibody :～抗体様分子による分子標的～2010
- Author(s)
  橋口周平、伊東祐二、田中孝一、松木園美穂、村岡賢、杉村和久
- Journal Title
  
  生化学
  
  Volume: 82 Pages: 710-726
- NAID
  10027502225
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] Immunological basis of M13 phage vaccine : Regulation under MyD88 and TLR9 signaling.2010
- Author(s)
  Shuhei Hashiguchi, Yuya Yamaguchi, Osamu Takeuchi, Shizuo Akira, Kazuhisa Sugimura
- Journal Title
  
  BBRC
  
  Volume: 402 Pages: 19-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310144
[Journal Article] Prion-conformation-specific human antibodies established from phage display library.2005
- Author(s)
  Shuhei Hashiguchi, Mayumi Yamamoto, Sho Kitamoto, Toshihiro Nakashima, Hitoki Yamanaka, Daisuke Ishibashi, Suehiro Sakaguchi, Shigeru Katamine, Yyji Ito, Kazuhisa Sugimura
- Journal Title
  
  Prions : Food and Drug Safety (Ed.T.Kitamoto)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16613008
[Journal Article] ファージディスプレイとヒト抗体エンジニアリング2004
- Author(s)
  杉村和久(他, 2名)
- Journal Title
  
  DOJIN News 109(1)
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-15310152
[Journal Article] ファージディスプレイとヒト抗体エンジニアリング2004
- Author(s)
  杉村和久(他、2名)
- Journal Title
  
  DOJIN News 109(1)
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310152
[Journal Article] ファージディスプレイ法:ヒト抗体ライブラリ2004
- Author(s)
  杉村和久
- Journal Title
  
  医学のあゆみ 211(7)
  
  Pages: 729-732
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310152
[Journal Article] Molecular characterization of a 10-kDa buckwheat molecule reactive to allergic patient's IgE2004
- Author(s)
  R.Matsumoto, K.Fujino, Y.Nagata, S.Hashiguchi, Y.Ito, Y.Aihara, Y.Takahashi, K.Maeda, K.Sugimura
- Journal Title
  
  Allergy Vol.59
  
  Pages: 533-538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] ファージディスプレイ法2003
- Author(s)
  (11)杉村和久(他, 2名)
- Journal Title
  
  Molecular Medicine 40(10)
  
  Pages: 1150-1158
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] Human single-chain Fv (scFv) antibody specific to human IL-6 with the inhibitory activity on IL-6-signaling2003
- Author(s)
  R.Gejima, K.Tanaka, T.Nakashima, S.Hashiguchi, Y.Ito, K.Yoshizaki, K.Sugimura
- Journal Title
  
  Human Antibodies 11
  
  Pages: 121-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] ファージディスプレイ法2003
- Author(s)
  杉村和久(他、2名)
- Journal Title
  
  Molecular Medicine(中山書店) 40(10)
  
  Pages: 1150-1150
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310152
[Journal Article] Affinity maturation of IL-6 mimic peptide IL-6/37 isolated from phage library2003
- Author(s)
  K.Tanaka, A.Miyazaki, K.Yoshinaga, S.Hashiguchi, Y.Ito, K.Yoshizaki, K.Sugimura
- Journal Title
  
  Peptide Science 2003
  
  Pages: 347-350
- NAID
  10012654364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] ファージディスプレイ法2003
- Author(s)
  杉村和久(他, 2名)
- Journal Title
  
  Molecular Medicine(中山書店) 40(10)
  
  Pages: 1150-1150
- Data Source
  KAKENHI-PROJECT-15310152
[Journal Article] Human Fc ε RI α - Specific Human Single-Chain Fv (scFv) Antibody with Antagonistic Activity toward IgE/Fc ε RI α -Binding2003
- Author(s)
  S.Hashiguchi, T.Nakashima, A.Nitani, T.Yoshihara, K.Yoshinaga, Y.Ito, Y.Maeda K.Sugimura
- Journal Title
  
  J.Biochem. 133
  
  Pages: 43-49
- NAID
  50000738710
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] Peptide phage library based on the tertiary structure of binding region on immuno-receptor2002
- Author(s)
  Kotaro Sakamoto, Yuji Ito, Keisuke Yoshinaga, Shuhei Hashiguchi, Kazuhisa Sugimura
- Journal Title
  
  Peptide Science 2002
  
  Pages: 279-280
- NAID
  80015974583
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] Enhanced immunogenicity of a single-dose antigen based on nanospheres with antigen presenting cell-targeting function2002
- Author(s)
  Y.Ito, Y.Kajiwara, A.Kimura, S.Hashiguchi, M.Akashi, K.Sugimura
- Journal Title
  
  Peptides 2002
  
  Pages: 520-521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] Peptide Mimics of Monocyte Chemoattractant Protein-1 (MCP-1) with an Antagonistic Activity2001
- Author(s)
  Masatomo Kaji, Masaomi Ikari, Shuhei Hashiguchi, Yuji Ito, Ryo Matsumoto, Teizo Yoshimura, Jun-ichi Kuratsu, Kazuhisa Sugimura
- Journal Title
  
  J.Biochem. 129
  
  Pages: 577-583
- NAID
  10007854595
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Journal Article] Structure-activity Relationship of Cytokine-mimic Peptide from Phage Library2001
- Author(s)
  Yuji Ito, Ryu Gejima, Satoko Okuhara^*, Ryo Matsumoto, Shuhei Hashiguchi, Kazuyuki Yoshizaki^*, Kazuhisa Sugimura
- Journal Title
  
  Peptide Science 2001
  
  Pages: 113-116
- NAID
  10009660265
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672325
[Patent] アミロイドBペプチドのミミック分子を用いたペプチドワクチン2010
- Inventor(s)
  杉村和久
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Number
  2009-538294
- Filing Date
  2010-03-15
- Data Source
  KAKENHI-PROJECT-21310144
[Patent] アミロイドβ線維化阻害ペプチド2008
- Inventor(s)
  杉村和久
- Industrial Property Rights Holder
  鹿児島大学
- Filing Date
  2008-10-22
- Overseas
- Data Source
  KAKENHI-PROJECT-21310144
[Patent] アミロイドβペプチドのミミック分子を用いたペプチドワクチン2008
- Inventor(s)
  杉村和久
- Industrial Property Rights Holder
  鹿児島大学
- Filing Date
  2008-10-22
- Overseas
- Data Source
  KAKENHI-PROJECT-21310144
[Patent] ヒト抗プリオン抗体及該抗体フラグメント2004
- Inventor(s)
  杉村和久
- Industrial Property Rights Holder
  鹿児島大学化学及血清療法研究所
- Industrial Property Number
  2004-316220
- Filing Date
  2004-10-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310152
[Presentation] アルツハイマー病モデルマウス(J20)脳内での、繊維状アミロイドβ(Aβ)に特異的な抗体(B7)によるAβプラークの免疫組織学的解析2011
- Author(s)
  川畑壮大朗、安部梨沙、田中孝一、大迫哲平、橋口周平、鈴木賢太朗、山田源、中島敏博、中河史朗、杉村和久
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Amyloid beta42-mimotope-displaying M13 phage induce anti-amyloid beta42antibody without adjuvant2011
- Author(s)
  大迫哲平、安部梨沙、川畑壮大朗、田中孝一、五反田卓摩、橋口周平、中河志朗、杉村和久
- Organizer
  第40回日本免疫学会学術集会記録
- Place of Presentation
  千葉,幕張メッセ
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Amyloid beta-42-mimotope displaying M13 bacteriophage for Vaccine vehicle of Alzheimer's disease2011
- Author(s)
  Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Sotaro Kawabata, Risa Abe, Shiro Nakagawa
- Organizer
  5th Vaccine and ISV Annual Global Congress
- Place of Presentation
  Seattle, USA
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Strong innate immunity to M13 bacteriophage : Implication for vaccine development2011
- Author(s)
  Shuhei Hashiguchi, Takuma Gotanda, Yuta Hamazoe, Kazuhisa Sugimura
- Organizer
  第40回日本免疫学会学術集会記録
- Place of Presentation
  千葉,幕張メッセ
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] アルツハイマー病モデルマウス(J20)脳内での、線維状アミロイドβ(Aβ)に特異的な抗体(B7)によるAβプラークの免疫組織学的解析2011
- Author(s)
  川畑壮大朗、安部梨沙、田中孝一、大迫哲平、橋口周平、鈴木賢太郎、山田源、中島敏博、中河志朗、杉村和久
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  兵庫,神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] M13 bacteriophage for vaccine vehicle of Alzheimer's disease2011
- Author(s)
  Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Sotaro Kawabata, Risa Abe
- Organizer
  1st Oxford International Bacteriophage Conference, Phage 2011
- Place of Presentation
  St Hilda's college Oxford University
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Amyloid beta 42-mimotope-displaying M13 phage induce anti-amyloid beta 42 antibody without adjuvant2011
- Author(s)
  Kazuhisa Sugimura, Risa Abe, Sotaro Kawabata, Teppei Osako, Takuma Gotanda, Shuhei Hashiguchi, Shiro Nakagawa
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Strong Innate Immunity to M13 Bacteriophage : Implication for Vaccine Development2011
- Author(s)
  Shuhei Hashiguchi, Takuma Gotanda, Yuta Hamazoe, Tsuyoshi Tsurumaru, Kazuhisa Sugimura
- Organizer
  5th Vaccine and ISV Annual Global Congress
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Amyloid Beta-42-Mimotope Displaying M13 Bacteriophage for Vaccine Vehicle of Arzheimer's Disease2011
- Author(s)
  Kazuhisa Sugimura, Shuhei Hashiguchi, Teppei Osako, Sotaro Kawabata, Risa Abe, Shiro Nakagawa
- Organizer
  5th Vaccine and ISV Annual Global Congress
- Place of Presentation
  Seattle
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Amyloid beta42-mimotope-displaying M13 phage induce anti-amyloid beta42antibody without adjuvant2010
- Author(s)
  Kazuhisa Sugimura, Risa Abe, Sotaro Kawabata, Teppei Osako, Takuma Gotanda, Shuhei Hashiguchi, Shiro Nakagawa
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] M13バクテリオファージ免疫におけるTLRファミリー分子の役割について2010
- Author(s)
  田原春菜、橋口周平、山口雄也、竹内理、審良静男、杉村和久
- Organizer
  BMB2010第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Immunological basis of phage vaccine as an experimental model using Alzheimer's disease model mice, J20 immunized with a mimotope-phage clone selected by a fibrillar Abeta42-specific antibody.2010
- Author(s)
  Yuya Yamaguchi, Shuhei Hashiguchi, Koichi Tanaka, Risa Abe, Kazuhisa Sugimura.
- Organizer
  The Immunotherapeutics and vaccine summit
- Place of Presentation
  Cambridge, MA
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Immunological basis of M13 phage vaccines : an effective vaccine design tested in a mouse model of Alzheimer's disease.2010
- Author(s)
  Hashiguchi S, Yamaguchi Y, Tahara H, Yamada T, Kai S, Abe R, Tanaka K, Sugimura K.
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  京都市
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] Essential role of MyD88 in humoral response to M13 bacteriophage in mice and negative role of TLR9 in IgG1 response.2010
- Author(s)
  Hashiguchi S, Yamaguchi Y, Takeuchi O, Akira S, Sugimura K.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21310144
[Presentation] アミロイドベータ1-42ミモトープをディスプレイしたM13ファージが誘導する免疫応答の解析2009
- Author(s)
  山口雄也, 橋口周平, 永尾宏子, 山田昴, 杉村和久
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21310144

1. ITO Yuji (60223195)

# of Collaborated Projects: 15 results

# of Collaborated Products: 13 results
2. HASHIGUCHI Syuhei (40295275)

# of Collaborated Projects: 11 results

# of Collaborated Products: 23 results
3. AZUMA Ichiro (50028411)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 古川純康 (10305154)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. NAKASHIMA Toshihiro

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
6. YOSHIZAKI Kazuyuki (90144485)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. 中島秀喜 (20192669)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. SAIKI Ikuo (80133776)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NISHIMOTO Norihiro (80273663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 佐伯武頼 (10056070)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 櫻田恵右 (80002161)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 明石満 (20145460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 福田恵温

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. BABA Masanori (70181039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ABEYAMA Kazuhiro (30284897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ISHIHARA Chiaki (90082172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TOKURA Seiich (40000806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小林清一 (30150246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大串哲彌 (10041568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 河野岩造 (60041761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 湯ノ口万友 (10094187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 肥後悟 (50041538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 山田源 (80174712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 神原賢治 (60305141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 越智隆弘 (80112035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 松本智成 (10311763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 金本大成 (20260755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. SEO Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 山本考史

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 井上誠

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SUGIMURA Kazuhisa 杉村 和久

杉村 和久 スギムラ カズヒサ

SUGIMRUA Kazuhisa 杉村 和久

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Amyloid beta-42-mimotope displaying M13 bacteriophage for vaccine vehicle of Alzheimer's diseasePrincipal Investigator

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Study on molecular targeting using phage dispky libraryPrincipal Investigator

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エイズ感染阻子分子の分子設計法の基礎研究Principal Investigator

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ファージディスプレイライブラリーを用いた感染防御と免疫制御法の開発Principal Investigator

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エイズ感染阻止分子の分子設計法の基礎研究Principal Investigator

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免疫制御分子の機能性ドメインミミックの分子設計と免疫制御Principal Investigator

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SUGIMURA Kazuhisa 杉村和久

杉村和久スギムラカズヒサ

SUGIMRUA Kazuhisa 杉村和久