YOSHIDA Haruyoshi 吉田治義

Researcher Number	80135574
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005 – 2011: 福井大学, 医学部, 教授 2010: 福井大学, 医学部, 助教 2003: University of Fukui, Faculty of Medical Science, Professor, 医学部, 教授 2002: 福井医科大学, 医学部, 教授 1986 – 1991: 京都大学, 医学部, 助教授 1986: Kyoto University, Faculty of Medicine, Department of Pathology., 医学部・第二病理, 助教授
Review Section/Research Field	Principal Investigator Laboratory medicine / Experimental pathology Except Principal Investigator Kidney internal medicine / 内分泌・代謝学 / Circulatory organs internal medicine / Kidney internal medicine / 内科学一般 / Immunology / Laboratory medicine / Experimental pathology
Keywords	Principal Investigator MCP-1 / VEGF / PAI-1 / マクロファージ / renal tubular cells / cDNA array / milieu / hypobaric hypoxic / progressive kidney diseases / ischemic hypoxia … More / TGF-β1 / 貧血マウス / 腎線維化 / 低酸素 / ケモカイン / 培養ヒト近位尿細管細胞 / マウス / 低気圧性低酸素 / 尿細管障害 / cDNAアレイ / 低酸素飼育マウス / 進行性腎疾患 / 虚血性低酸素 / バイオマーカー / ヘテロマルチマー / 人工心肺手術 / 酸化ストレス / チオレドキシン / 急性腎障害 / 尿中マーカー / エキソゾーム分画 / 尿細管上皮細胞 / 血管透過性因子 / 尿細管間質障害 / 進行性腎障害 / 糖尿病性腎症モデルマウス / 糖尿病 / 高血糖 / CD34 / メサンギオリーシス / 微小血管瘤 / 結節性硬化 / 糸球体硬化 / 慢性低酸素 / dbマウス / db / 糖尿病性腎症 / 腎炎モデル動物 / PDGF / 血小板由来成長因子 / 糸球体肥大 / 細胞増殖因子 / メサンギウム細胞 / 糸球体腎炎 … More Except Principal Investigator PAI-1 / 低酸素 / TNF-α / PPAR / MCP-1 / 脂肪酸結合蛋白 / Atherosclerosis / hypoxia / renal tubular cells / PPAR knockout mice / bile acid-binding protein / ペルオキシゾーム増殖薬活性化受容体(PPAR) / TGF-β / 尿細管上皮細胞 / 腎臓学 / 多量体IgA / IgA腎症 / Oxidized LDL receptor / Oxidized LDL / Probucol / Foam cell / マクロファージ / プロブコール / WHHLウサギ / 粥状動脈効果 / 酸化LDL受容体 / 酸化LDL / プロブコ-ル / 泡沫細胞 / 粥状動脈硬化 / Prostaglandin,Lipoprotein / Familial Hypercholesterolemia / コレステロール / リポタンパク / プロスタグランディン / 家族性高コレステロール血症 / 動脈硬化 / avidity / IgG4 subclass / anti-DNA antibodies / membranous nephropathy / lupus nephritis / antibody clonotypes / immune complexes / 等電点電気泳動 / 抗体の親和性 / IgG4サブクラス / 抗DNA抗体 / 膜性腎症 / ループス腎炎 / 抗体クロノタイプ / 免疫複合体 / fatty acid-binding proteins / peroxisome proliferator-ativiated receptors / human proximal renal tubular cells / renal fibrosis / 脂質親和性転写因子 / lipid-binding proteins / proximal renal tubular cells / 抗炎症作用 / 脂質転送蛋白 / ペルオキシゾーム増殖薬反応性受容体 / ヒト近位尿細管上皮細胞 / 進行性腎障害 / reporter assay / lipid-binding protein / reporter_assy / reporter assy / Lipid-binding protein / day mouse / chronic glomerulonephritis / gq70 / Monoclonal IgA / IgA nephropathy / DBA_2マウス / gP70 / ddYマウス / ddyマウス / 慢性腎炎 / gp70 / モノクロナルIgA / YT細胞 / 抗FcαR抗体 / LAK細胞 / p75 / ILー2R / YTAー1抗体 / IgE結合因子 / 可溶性FcεR2 / ELISA法 / プラスミノーゲンアクチベーターインヒビター1(PAI-1) / プラスミノーゲンアクチベーターインヒビタ-1(PAI-1) / ファルネソイドX受容体(FXR) / 肝X受容体(LXR) / アンジテンシンII受容体拮抗薬 / 炎症 / メサンギウム細胞 / ペルオキシゾーム増殖剤応答性受容体 / ポドサイト / 糖尿病性腎症 / 糖尿病 / VEGF / ハイドロコルチゾン / ミネラロコルチコイド受容体 / 脂肪酸結合蛋白(FABP) / 内皮細胞増殖因子(VEGF) / プラスミノーゲンアクチベーターインヒビター-1(PAI-1) / ピオグリタゾン / デキサメサゾン / グルココルチコイド受容体 / FABP / GR / 腎線維化 / アミロイド / 自己抗体 / 免疫複合体腎炎 / 小腸パイエル板 / 免疫抑制剤Cyclophosphamide / 老化促進モデルマウス(SAM) / 自己免疫異常 / 加齢 / 等電点 / メサンギウム増殖性糸球体腎炎 / ddY(マウス) Less

新規尿検査としての尿中エキソゾーム分画中腎症マーカー蛋白の検出Principal Investigator
- Principal Investigator
  
  吉田治義
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Podocyte injury induced by chronic hypoxia in diabetic db/db mice
- Principal Investigator
  
  TAKAHASHI Naoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Investigation for anti-renal fibrotic effects of lipid-binding proteins and lipid-activated nuclear receptors and search for new therapeutic reagents
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
Study on chronic hypoxia-related advancement factor in a mouse model of diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Haruyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Analysis for anti-inflammatory and anti-fibrotic actions of lipid transfer proteins and lipid-activated transcription factors in the progressive renal injury
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
Studies on the Pathogenesis and the Modulation of Kidney Diseases in Hypoxic MilieuPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Haruyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Investigation on anti-inflammatory effects of lipid-binding proteins and lipophilic transcriptional factors in progression of renal injury.
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
Investigation on anti-inflammatory effects of lipid-binding proteins in progression of renal injury.
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Faculty of Medical Sciences, University of Fukui
モデル動物を用いた糸球体メサンギウム細胞増殖機構の分子病理学的研究Principal Investigator
- Principal Investigator
  
  吉田治義
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
促進老化の進展における免疫異常の関与についての研究!自然発症老化促進モデルマウス(SAM)に対する免疫抑制剤投与の効果
- Principal Investigator
  
  吉岡秀幸
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Institution
  Kyoto University
IgA腎症モデルマウス(ddY系)におけるメサンギウム病変成立機序の解析
- Principal Investigator
  
  TAKEUCHI Eiji
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
Investigation of nephritogenicity using murine model of IgA nephrop
- Principal Investigator
  
  MUSO Eri
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KYOTO UNIVERSITY
抗ヒトリンパ球レセプター抗体とレセプター遺伝子の作製による免疫療法の開発
- Principal Investigator
  
  淀井淳司
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Study for the initial events of atherosclerosis in WHHL-rabbit and its prevention.
- Principal Investigator
  
  KITA Toru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  KYOTO UNIVERSITY
Study for the initial event of athcrosclerosis.
- Principal Investigator
  
  KITA Toru
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kyoto University
Detection of Specific Antibody Clonotypes in Various Immune Complex Glomerulonephritis.
- Principal Investigator
  
  TAMURA Tadao
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto University

All 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] 蛋白尿、今日の診断指針第6版2010
- Author(s)
  吉田治義
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19590550
[Book] 蛋白尿・血尿、臨床検査のガイドラインJSIM 20092009
- Author(s)
  吉田治義
- Publisher
  宇宙堂八木書店
- Data Source
  KAKENHI-PROJECT-19590550
[Book] Cardionephrology 102008
- Author(s)
  Haruyoshi Yoshida
- Publisher
  Nuova Editoriale Bios
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Severe intraglomerular detachment of podocytes in a Gitelman syndrome patient2012
- Author(s)
  Naoki Takahashi, Hideki Kimura, Shinichi Mizuno, Masanori Hara, Yoshiaki Hirayama, Hiroyuki Kurosawa, Shouji Tsutaya, Minoru Yasujima, Seiji Yokoi, Daisuke Mikami, Kenji Kasuno, Hironobu Naiki, Masayuki Iwano and Haruyoshi Yoshida
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: (in press) Issue: 3 Pages: 16-16
- DOI
  10.1007/s10157-012-0624-4
- NAID
  10030808799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617, KAKENHI-PROJECT-24590686
[Journal Article] Smaller LDL size as a possible risk factor for the prevalence of coronary artery diseases in hemodialysis patients-Associations of CETP and the hepatic lipase gene polymorphism with LDL size2011
- Author(s)
  Kimura H, Miyazaki R, Imura T, Masunaga S, Shimada A, Mikami D, Kasuno K, Takahashi N, Hirano T, Yoshida H
- Journal Title
  
  Nephrology(Carlton)
  
  Volume: 16 Issue: 6 Pages: 558-566
- DOI
  10.1111/j.1440-1797.2011.01454.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617, KAKENHI-PROJECT-21591024
[Journal Article] レドックス制御因子チオレドキシン研究の臨床展開2011
- Author(s)
  糟野健司, 木村秀樹, 高橋直生, 三上大輔, 横山由就, 信川泰成, 重見研司, 吉田治義
- Journal Title
  
  臨床病理
  
  Volume: 59 Pages: 189-195
- NAID
  10029427045
- Data Source
  KAKENHI-PROJECT-22659113
[Journal Article] 腎障害をきたす全身疾患-最新の進歩III.パラプロテイン血症2.アミロイドーシス2011
- Author(s)
  高橋直生, 木村秀樹, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 1282-1288
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 腎臓病の扉をひらくキーワードレドックス制御因子チオレドキシン研究の臨床展開2011
- Author(s)
  糟野健司、木村秀樹、高橋直生、三上大輔、横山由就、信川泰成、重見賢治、吉田治義
- Journal Title
  
  臨床病理
  
  Volume: 59 Pages: 189-195
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Smaller LDL size as a possible risk factor for the prevalence of coronary artery diseases in hemodialysis patients-Associations of CETP and the hepatic lipase gene polymorphism with LDL size.2011
- Author(s)
  Kimura H, Miyazaki R, Imura T, Masunaga S, Shimada A, Mikami D, Kasuno K, Takahashi N, Hirano T, Yoshida H.
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Glucocorticoid enhances hypoxia-and/or transforming growth factor-β-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells2011
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Kasuno K, Takahashi N, Yoshida H
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Issue: 1 Pages: 34-40
- DOI
  10.1007/s10157-010-0351-7
- NAID
  10029004358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 腎障害をきたす全身疾患-最新の進歩III.パラプロテイン血症2011
- Author(s)
  高橋直生、木村秀撒、吉田治義、内木宏延
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 1282-1288
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Glucocorticoid enhances hypoxia- and/or transforming growth factor-ss-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells.2011
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Kasuno K, Takahashi N, Yoshida H.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Tubulointerstitial nephritis with IgM-positive plasmacytoid large lymphocyte infiltration in a patient with primary biliary cirrhosis and Sjoegren's syndrome.2010
- Author(s)
  Naoki Takahashi, Hideki Kimura, Yumiko Kawajiri, Daisuke Mikami, Chie Yamamoto, Kenji Kasuno, Naofumi Imai, Takeshi Kuroda, Shinichi Nishi, Makoto Yamamoto, Haruyoshi Yoshida.
- Journal Title
  
  Clin Nephrol
  
  Volume: 74 Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] A specific serum IgA antibody discriminates pneumonia from colonization state in patients with Pseudomonas aeruginosa in sputum culture.2010
- Author(s)
  Masanori Yamashita, Yukio Hida, Hidehiro Sugimoto, Naoki Takahashi, Hideki Kimura, Yasuo Nakatomi, Haruvoshi Yoshida, Takeshi Ishizaki.
- Journal Title
  
  J Microbiol Methods
  
  Volume: 198 Pages: 198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Osteoprotegerin(OPG)2010
- Author(s)
  高橋直生、木村秀樹、糟野健司、吉田治義
- Journal Title
  
  日本臨床増刊号
  
  Volume: 68 Pages: 152-155
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] A specific serum IgA antibody discriminates pneumonia from colonization state in patients with Pseudomonas aeruginosa in sputum culture2010
- Author(s)
  Masanori Yamashita, Yukio Hida, Hidehiro Sugimoto, Naoki Takahashi, Hideki Kimura, Yasuo Nakatomi, Haruyoshi Yoshida and Takeshi Ishizaki
- Journal Title
  
  J Microbiol Methods
  
  Volume: 82 Pages: 198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 慢性腎臓病 (CKD) とは2010
- Author(s)
  吉田治義
- Journal Title
  
  日本臨床検査自動化学会誌 35巻
  
  Pages: 167-170
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] 急性腎障害とレドックス発現2010
- Author(s)
  糟野健司, 武曾恵理, 白川喜一, 東義人, 淀井淳司, 吉田治義
- Journal Title
  
  腎とフリーラジカル
  
  Volume: 10 Pages: 102-106
- Data Source
  KAKENHI-PROJECT-22659113
[Journal Article] 特集:広範囲血液・尿生化学検査,免疫学的検査(4)-その数値をどう読むか-Osteoprotegerin(OPG)2010
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 風間順一郎, 吉田治義
- Journal Title
  
  日本臨床
  
  Pages: 152-155
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Tubulointerstitial nephritis with IgM-positive plasmacytoid large lymphocyte infiltration in a patient with primary biliary cirrhosis and Sjoegren's syndrome2010
- Author(s)
  Naoki Takahashi, Hideki Kimura, Yumiko Kawajiri, Daisuke Mikami, Chie Yamamoto, Kenji Kasuno, Naofumi Imai, Takeshi Kuroda, Shinichi Nishi, Makoto Yamamoto and Haruyoshi Yoshida
- Journal Title
  
  Clin Nephrol
  
  Volume: 74 Issue: 07 Pages: 74-80
- DOI
  10.5414/cnp74074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 尿中チオレドキシンの急性腎障害(AKI)マーカーとしての有用性2010
- Author(s)
  糟野健司, 吉田治義
- Journal Title
  
  Medical Technology
  
  Volume: 38 Pages: 870-871
- Data Source
  KAKENHI-PROJECT-22659113
[Journal Article] Dexamethasone enhances basal and TNF-α-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11β- hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant 24
  
  Pages: 1759-1765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] P66 Shcの光と陰 : 酸化・老化を促進するタンパク?どうして必要なの?2009
- Author(s)
  糟野健司, 吉田治義, K Irani
- Journal Title
  
  基礎老化研究 33
  
  Pages: 17-22
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Dexamethasone enhances basal and TNF-alpha-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11beta-hydroxysteroid dehydrogenase 2 status in human proximalrenal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplan
  
  Volume: 24 Issue: 6 Pages: 1759-1765
- DOI
  10.1093/ndt/gfn756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617, KAKENHI-PROJECT-21591024
[Journal Article] 二次性ネフローゼ症候群の病態 3. その他の二次性ネフローゼ症候群2009
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌 98巻
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Dexamethasone enhances basal and TNF-α-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11β- hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant 24
  
  Pages: 1759-1765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Dexamethasone enhances basal and TNF-{alpha}-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11β-hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] ネフローゼ症候群:診断と治療の進歩, III.二次性ネフローゼ症候群の病態3.その他の二次性ネフローゼ症候群2009
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 98 Pages: 75-81
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 二次性ネフローゼ症候群の病態 3. その他の二次性ネフローゼ症候群2009
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌 98
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment2009
- Author(s)
  Takahashi N, Kimura H, Kitai R, Sato M, Yoneda M, Yamamoto C, Mikami D, Kuriyama M, Kubota T, Itoh H, Yoshida H
- Journal Title
  
  Clin Nephrol 72
  
  Pages: 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Lipopoly- saccharide-triggered acute aggravation of mesangioproliferative glomerulo- nephritis through activation of coagulation in a high IgA strain of ddY mice2009
- Author(s)
  Shimosawa M, Sakamoto K, Tomari Y, Kamikado K, Otsuka H, Liu N, Kitamura H, Uemura K, Nogaki F, Mori N, Muso E, Yoshida H, Ono T
- Journal Title
  
  112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment2009
- Author(s)
  Takahashi N, Kimura H, Kitai R, Sato M, Yoneda M, Yamamoto C, Mikami D, Kuriyama M, Kubota T, Itoh H, Yoshida H
- Journal Title
  
  Clin Nephrol 72
  
  Pages: 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment2009
- Author(s)
  Naoki Takahashi, Hideki Kimura, Ryuhei Kitai, Mamiko Sato, Makoto Yoneda, Chie Yamamoto, Daisuke Mikami, Masaru Kuriyama, Toshihiko Kubota, Hiroshi Itoh, and Haruyoshi Yoshida
- Journal Title
  
  Clin Nephrol
  
  Volume: 72 Pages: 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH2008
- Author(s)
  Hasegawa K, Tsutsumi-Yasuhara S, Ookoshi T, Ohhashi Y, Kimura H, Takahashi N, Yoshida H, Miyazaki R, Goto Y, Naiki H
- Journal Title
  
  Biochem J 416
  
  Pages: 307-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] 尿細管間質障害の進行における低酸素機序2008
- Author(s)
  吉田治義
- Journal Title
  
  日本臨床検査自動化学会誌 33巻
  
  Pages: 3-8
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] A natural PPAR-γ agonist, 15-deoxy-delta 12,14- prostaglandin J2, may act as an enhancer of PAI-1 in human proxymal renal tubular cells under hypoxic and inflammatory conditions2008
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Takahashi N, Fujii H, Ishihara S, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 2496-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] growth of β2-microglobulin-related amyloid fobrils by non-esterified fatty acids at a neutral pH2008
- Author(s)
  Hasegawa K, Tsutsumi-Yasuhara S, Ohhashi Y, Kimura H, Takahashi N, Yoshida H, Miyazaki R, Goto Y, Naiki H
- Journal Title
  
  Biochem J 416
  
  Pages: 307-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] The clinical significance of abnormal diurnal blood pressure variation in healthy late middle-aged and older adults2008
- Author(s)
  Hamada T, Murata T, Narita K, Takahashi T, Wada Y, Kimura H, Yoshida H
- Journal Title
  
  Bolld Pressure 17
  
  Pages: 134-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] A natural PPAR-γ agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions2008
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Takahashi N, Fujii H, Ishihara S and Yoshida H
- Journal Title
  
  Nephrol Dialysis Transplant 23
  
  Pages: 2496-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] 尿細管間質障害の進行における低酸素機序2008
- Author(s)
  吉田治義
- Journal Title
  
  日本臨床検査自動化学会会誌 33
  
  Pages: 3-8
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Rapid remission of minimal change disease with angiotensin II antagonist treatment in a type 1 diabetic patient with no diabetic nephropathy2008
- Author(s)
  Takahashi N, Kimura H, Nishi S, Yamamoto C, Kawajiri Y, Makino Y, Konoshita T, Miyamori I, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant Plus 5
  
  Pages: 375-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Lysophospholipids induce the nucleation and extension of beta2-microglobulin-related amyloid fibrils at a neutral pH2008
- Author(s)
  Ookoshi T, Hasegawa K, Ohhashi Y, Kimura H, Takahashi N, Yoshida H, Miyazaki R, Goto Y, Naiki H
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 3247-3255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] 尿細管間質障害の進行における低酸素機序2008
- Author(s)
  吉田治義
- Journal Title
  
  日本臨床検査自動化学会誌 33
  
  Pages: 3-8
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Endocapillary proliferative glomerulo-nephritis with crescent formation and concurrent tubulointerstitial nephritis complicating retroperitoneal fibrosis with a high serum level of IgG42007
- Author(s)
  Katano K, Kimura H, Yoshida H
- Journal Title
  
  Clin Nephrol 68
  
  Pages: 308-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-γ in human proximal renal tubular cells2007
- Author(s)
  Li X, Kimura H, Hirota K, Sugimoto H, Kimura N, Takahashi N, Fujii H, Yoshida H
- Journal Title
  
  Nephrol Dialysis Transplant 22
  
  Pages: 1041-1051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Presentation] レドックス制御蛋白「尿中チオレドキシン」の酸化ストレス特異的急性腎障害(AKI)マーカーとしての有用性2011
- Author(s)
  糟野健司, 木村秀樹、高橋直生, 三上大輔, 横山由就、武曾恵里、信川泰成, 重見研司、吉田治義
- Organizer
  第54回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 急性腎障害(AKI)の病因別診断に尿中チオレドキシンが有用である2011
- Author(s)
  糟野健司、木村秀樹、高橋直生, 三上大輔, 横山由就, 村瀬詠廉, 横井靖二, 信川泰成, 吉田治義
- Organizer
  第58回日本臨床検査医学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Overexpression of Human Liver-Fatty Acid-Binding Protein (L-FABP) Endogenously Enhances Peroxisome Proliferator-Activated Receptor (PPAR)-α Activity Possibly Via Inducing Hepatocyte Nuclear Factor (HNF)-4α in Immortalized Mouse Proximal Renal Tubular Cells (mProx)2011
- Author(s)
  Hideki Kimura, Daisuke Mikami, Kazuko Kamiyama, Kenji Kasuno, Naoki Takahashi, Takeshi Sugaya, Haruyoshi Yoshida
- Organizer
  44th American Society of Nephrology annual meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 血液透析(HD)患者の虚血性心疾患(CAD)の危険因子としての低比重リポ蛋白(LDL)サイズの減少2011
- Author(s)
  木村秀樹,三上大輔, 嶋田章弘、宮崎良一、糟野健司, 高橋直生, 吉田治義、平野勉
- Organizer
  第54回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] レドックス制御蛋白「尿中チオレドキシン」の酸化ストレス特異的急性腎障害(AKI)マーカーとしての有用性2011
- Author(s)
  糟野健司、武曾恵理、木村秀樹、高橋直生、三上大輔、横山由就、信川泰成、重見研司、吉田治義
- Organizer
  日本腎臓学会総会2011
- Place of Presentation
  横浜
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Urinary Thioredoxin Is an Oxidative Stress Associated Biomarker of Acute Kidney Injury2011
- Author(s)
  Kenji Kasuno, Eri Muso, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Yoshinari Yokoyama, Yasunari Nobukawa, Haruyoshi Yoshida.
- Organizer
  International Congress on Uremia Research and Toxicity2011
- Place of Presentation
  名古屋
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Urinary Thioredoxin 1 Is an Oxidative Stress-Specific Biomarker of Acute Kidney Injury2011
- Author(s)
  Kenji Kasuno, Eri Muso, Hideki Kimura, Naoki Takahashi, Yasunari Nobukawa, Kiyoshi Mori, Haruyoshi Yoshida
- Organizer
  44th American Society of Nephrology annual meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 血液透析患者の鉄欠乏性貧血における網赤血球ヘモグロビン等量の有用性2011
- Author(s)
  横山由就, 三上大輔, 糟野健司, 高橋直生, 木村秀樹, 山本智恵, 宮城恭子, 宮崎良一, 吉田治義
- Organizer
  第56回日本透析医学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Urinary Thioredoxin Is a Quick and Predictive Biomarker of Acute Kidney Injury.2010
- Author(s)
  Kenji Kasuno, Eri Muso, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Tomomi Kurose, Yasunari Nobukawa, Haruyoshi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Urinary Thioredoxin Is a Quick and Predictive Biomarker of Acute Kidney Injury2010
- Author(s)
  Kenji Kasuno, Eri Muso, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Tomomi Kurose, Yasunari Nobukawa, Haruyoshi Yoshida.
- Organizer
  米国腎臓学会ASN2010
- Place of Presentation
  米国デンバー
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Acceleration of Diabetic Glomerulopathy in db/db Mice in Chronic Hypoxia.2010
- Author(s)
  Naoki Takahashi, Hideki Kimura, Kazuko Kamiyama, Tomomi Kurose, Hidehiro Sugimoto, Toshio Imura, Dai suke Mikami, Kenji Kasuno, Haruyo shi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 低酸素下のヒト近位尿細管細胞において、グルココルチコイドはPAI-1の産生を増強しVEGFの産生を抑制する2010
- Author(s)
  鳥居国雄, 木村秀樹, 上山和子, 杉本英弘, 岡田敏春, 山野智子, 関口清美, 三上大輔, 糟野健司, 高橋直生, 吉田治義
- Organizer
  第57回日本臨床検査医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 腎不全患者を対象とした活性化血小板の測定および血小板凝集能検査との比較検討2010
- Author(s)
  岡田敏春, 高橋直生, 鳥居国雄, 山野智子, 関口清美, 木村秀樹, 吉田治義
- Organizer
  第57回日本臨床検査医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 慢性低酸素環境におけるdb/dbマウスの糖尿病性糸球体硬化の進展2010
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 井村敏雄, 杉本英弘, 吉田治義
- Organizer
  日本腎臓学会
- Place of Presentation
  神戸
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 招待シンポジウム「腎臓病の扉を開くキーワード」尿中チオレドキシンの急性腎障害(AKI)マーカーとしての有用性2010
- Author(s)
  糟野健司、木村秀樹、高橋直生、三上大輔、横山由就、吉田治義
- Organizer
  日本臨床化学会東海北陸支部総会
- Place of Presentation
  福井
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] LDL Size Reduction as a Possible Risk Factor for the Prevalence of Coronary Artery Diseases in Hemodialysis Patients.2010
- Author(s)
  Hideki Kimura, Ryoichi Miyazaki, Shinya Masunaga, Akihiro Shimada, Toshio Imura, Daisuke Mikami, Kenji Kasuno, Naoki Takahashi, Tsutomu Hirano, Haruyoshi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 高糖、炎症、低酸素状態下の近位尿細管細胞におけるVEGF-A、C発現動態の解析ステロイド作用の検討も含めて2010
- Author(s)
  木村秀樹, 杉本英弘, 上山和子, 三上大輔, 糟野健司, 高橋直生, 吉田治義
- Organizer
  第53回日本腎臓学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Discrete Regulation of VEGF-A and -C in Human Proximal Renal Tubular Cells under Hypoxic and/or Inflammatory Conditions-Inhibitory Effects of Glucocorticoids on Basal and Inducible VEGF Expression.2010
- Author(s)
  Hideki Kimura, Hidehiro Sugimoto, Kazuko Kamiyama, Daisuke Mikami, Kenji Kasuno, Naoki Takahashi, Haruyoshi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 血液透析患者における低比重リポ蛋白サイズの独立規定因子の解析2010
- Author(s)
  木村秀樹, 宮崎良一, 井村敏雄, 嶋田章弘, 増永慎也, 三上大輔, 糟野健司, 高橋直生, 平野勉, 吉田治義
- Organizer
  第57回日本臨床検査医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Urinary Thioredoxin Is a Predictive Biomarker of Acute Kidney Injury2010
- Author(s)
  Kenji Kasuno, Eri Muso, Junji Yodoi, Kiichi Shirakawa, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Haruyoshi Yoshida.
- Organizer
  国際腎臓学会ISN2010
- Place of Presentation
  京都
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Chronic hypoxia induces proximal tubular expression of plasminogen activator inhibitor-1 (PAI-1), major progression factor of diabetic kidney disease2008
- Author(s)
  Yoshida H
- Organizer
  12th European Meeting on Cardionephrology
- Place of Presentation
  Assisi, Italy
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-19590550
[Presentation] Plasminogen activator inhibitor-1 (PAI-1) as a clinical progression marker of diabetic nephropathy is secreted by proximal tubular cells.2008
- Author(s)
  Haruyoshi Yoshida
- Organizer
  XLV ERA-EDTA Congres
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2008-05-13
- Data Source
  KAKENHI-PROJECT-19590550

1. KIMURA Hideki (20283187)

# of Collaborated Projects: 9 results

# of Collaborated Products: 54 results
2. TAKAHASHI Naoki (30377460)

# of Collaborated Projects: 4 results

# of Collaborated Products: 48 results
3. TAKEUCHI Eiji (80179605)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MUSO Eri (10190852)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. FUJII Hiroshi (90165340)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. HIROTA Kiichi (00283606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SUGAYA Takeshi (40381561)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. KASUNO Kenji (60455243)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
9. KITA Toru (60161460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 杉山武敏 (20030851)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TAMURA Tadao (70026855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. DOI Toshio (60183498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WATANABE Yoshio (00031401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MATSUMORI Akira (70135573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NARUMIYA Shuh (70144350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 嶋田俊秀 (00235623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 吉岡秀幸 (30231690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松本光弘 (20229579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岡田敏春 (20534027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 淀井淳司 (80108993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 稲本俊 (10135577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 翠川修 (40025515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小澤和恵 (00026858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 高見正明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 廣田喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIDA Haruyoshi 吉田 治義

Research Projects

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新規尿検査としての尿中エキソゾーム分画中腎症マーカー蛋白の検出Principal Investigator

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Study on chronic hypoxia-related advancement factor in a mouse model of diabetic nephropathyPrincipal Investigator

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Studies on the Pathogenesis and the Modulation of Kidney Diseases in Hypoxic MilieuPrincipal Investigator

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モデル動物を用いた糸球体メサンギウム細胞増殖機構の分子病理学的研究Principal Investigator

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YOSHIDA Haruyoshi 吉田治義

[Book] 蛋白尿、今日の診断指針第6版2010