Fujii Hiroshi 藤井博

… Alternative Names

FUJII HIROSHI 藤井博

FUJII Hiroshi 藤井博

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Researcher Number	90165340
Other IDs
External Links
Affiliation (Current)	2022: 信州大学, 農学部, 特任教授 2022: 信州大学, 学術研究院農学系, 教授
Affiliation (based on the past Project Information) *help	2017: 信州大学, 学術研究院農学系, 教授 2014: 信州大学, 学術研究院農学系, 教授 2006 – 2013: 信州大学, 農学部, 教授 2005 – 2006: 新潟大学, 医歯学系, 助教授 2004: 新潟大学, 大学院・医歯学総合研究科, 助教授 … More 2000 – 2003: 新潟大学, 医学部, 助教授 2001 – 2002: 新潟大学, 大学院・医歯学総合研究科, 助教授 1993 – 1998: NIIGATA UNIVERSITY SCHOOL OF MEDICINE ASSOCIATE PROFESSOR, 医学部, 助教授 1997: 新潟大学, 医学部・生化学第二講座, 助教授 1992: 新潟大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Structural biochemistry Except Principal Investigator General medical chemistry / Kidney internal medicine / Biological Sciences / Kidney internal medicine / Food science / Applied microbiology / Laboratory medicine / 医薬分子機能学 / Bioorganic chemistry
Keywords	Principal Investigator シグナル伝達 / 胆汁酸 / 核内受容体 / 脂肪酸 / ras / signal transduction / PPAR / LXR / FXR / SREBP … More / 脂肪酸結合タンパク質 / 遺伝子発現 / 癌転移 / miRNA / マイクロRNA / 蛋白質の脂質修飾 / 蛋白質のプレニル化 / イソプレノイド / 分子シャペロン / Ras / posttranslational lipid modification / protein modification / isoprenoid / molecular chaperon / 核内レセプター / 転写制御 / コレステロールホメオスタシス / Nuclear Receptor / Signal Transduction / Transcriptional Regulation / Bile Acids / 遺伝子 / 発現制御 / 脂質 / トランスポーター / gene / regulation of expression / fatty acid / bile acid / lipid / nuclear receptor / transporter … More Except Principal Investigator PAI-1 / PPAR / スクアレン・エポキシダーゼ / コレステロール / H-FABP / I-15P / I-FABP / NF-Y / TNF-α / 脂肪酸結合蛋白(FABP) / D8S508 / CETP / プロテオミクス / 成長円錐 / リン酸化 / シンタキシン / ミオシンV / FABP / 低酸素 / 脂肪酸結合蛋白 / 分子モデリング / 抗アミロイド効果 / 心筋梗塞 / L-FABP / C-FABP / スクアレン・エポキシダーゼ(SE) / 阻害剤 / スクアレン / 動脈硬化 / 高脂血症 / スクリーニング / バイオセンサー / SRE / 転写調節 / lipid-binding protein / cell culture / bile acid-binding protein / PPAR knockout mice / renal tubular cells / MCP-1 / hypoxia / 微小管 / 表面プラズモン共鳴 / SCG10 / アクチン調節蛋白質 / RNAi / 神経極性形成 / コンドロイチン硫酸 / 遺伝子改変マウス / GAP-43 / 骨端軟骨 / プロテオーム / カルシウム / ノックインマウス / 脂肪酸結合蛋白質 / 免疫染色 / インタラクトミクス / 原子間力顕微鏡 / 開口放出 / 腎臓学 / 尿細管上皮細胞 / 腎線維化 / GR / TGF-β / グルココルチコイド受容体 / ペルオキシゾーム増殖薬活性化受容体(PPAR) / デキサメサゾン / ピオグリタゾン / プラスミノーゲンアクチベーターインヒビター-1(PAI-1) / 内皮細胞増殖因子(VEGF) / ミネラロコルチコイド受容体 / ハイドロコルチゾン / VEGF / アミロイド線維形成 / 天然フェノール化合物 / フェノール化合物誘導体 / リポフィル化 / グリコシル化 / アミロイド型蛋白質 / アミロイド型タンパク質 / アミロイド線維 / 酵素合成 / フェノール化合物 / L68Q型シスタチン / アミロイドβ蛋白質 / アポリポタンパク質 / 安全性 / シスタチン / アミロイド性蛋白質 / カテコール誘導体 / 抗アミロイドーシス食品素材 / 糸状菌の光応答 / 青色光刺激 / シキミ酸蓄積 / 遺伝子発現制御 / タンパク質発現制御 / 新規有用物質生産法の開発 / 一次代謝経路の光制御 / 発光ダイオード / 糸状菌 / タミフル製造原料 / 一次代謝経路の制御 / 遺伝子発現・タンパク質発現 / 有用物質生産 / キノコ菌糸 / 代謝経路の光制御 / メタボローム解析 / シキミ酸経路 / 光質効果 / 光強度効果 / 遺伝子発現解析 / 機序解明 / キノコの光応答 / ヒラタケ菌糸 / シキミ酸 / sterol regulatory element(SRE) / フラビン酵素 / モノオキシゲナーゼ / ラット / sterol regulatory element (SRE) / 酵母 / Squalene Epoxidase / Sterol Regulatory Element(SRE) / Cholesterol / Monooxygenase / Flavoenzyme / Rat / 血清マーカー / Fatty Acid-Binding Protein / Myocardial Infarct / Serum Mark / 糖尿病 / 虚血性腸疾患 / 蛍光脂肪酸プローブ / 脂肪酸 / ステロイド産生臓器 / Fatty Acid-Binding Protein (FABP) / Diabetes Mellitus / Ischaemic Intestinal Diseases / Fluorescent Fatty Acid / ラノステロール合成酵素(LS) / 酵母トランスフォーマント / クローニング / 抗真菌剤 / スクアレン合成酵素(SS) / 生育阻害 / スクアレンエポキシダーゼ / Squalene epoxidase (SE) / Lanosterol synthase (LS) / Yeast transformant / Inhibitor / Cloning / Antifungal drug / Squalene synthase (SS) / Growth inhibition / エポキシダーゼ(SE) / ベンゾフェノン誘導体 / HMG-CoA還元酵素 / LDL-レセプター / 遺伝子発現 / 染色体8q24.13 / squalene epoxidase(SE) / benzophenone derivatives / HMG-CoA reductase / LDL-receptor / gene expression / chromosome 8 q24.13 / ラノステロール合成酵素 / SREBP / 転写因子 / 膜結合領域 / 転写調整 / 遺伝子構造(イントロン-エクソン構成) / HeLa細胞 / 発現調節 / プロモーター領域 / 染色体8 / squalene epoxidase / lanosterol synthase / cholesterol / transcriptional regulation / SREBP (sterol regulatory element binding protein) / transcription factor / membrane binding domain / 腎糸球体 / 脂質結合蛋白 / 糸球体上皮細胞足突起 / アポE蛋白 / 遺伝子多型 / glomeruli / foot process / apolipoprotein E / genetic polymorphism / スクアレンエポキシダーゼ(SE) / Langer-Giedeon症候群 / ステロールレギュレトリーエレメント(SRE) / SE機能ドメイン / 核内レセプター / オキシステロール / スクアレンエポキシダーゼ(SE) / Squalene Epoxidase (SE) / Langer-Giedion Syndrome / Transcriptional Regulation / Sterol Regulatroy Element (SRE) / SE Functional Domain / Intranuclear Receptor / Oxysterol / kidney / eosinophil / homocysteine / Immuno histochemistry / Macrophage / Homocysteine / kidnev / Hold-binding nrotein / PAI- 1 / GETP / eosmophil / homocvsteine / Lipid-binding protein / reporter assy / reporter_assy / reporter assay / 進行性腎障害 / ヒト近位尿細管上皮細胞 / ペルオキシゾーム増殖薬反応性受容体 / 脂質転送蛋白 / 抗炎症作用 / proximal renal tubular cells / lipid-binding proteins / 脂質親和性転写因子 / renal fibrosis / human proximal renal tubular cells / peroxisome proliferator-ativiated receptors / fatty acid-binding proteins / 天然物 / 生理活性物質 / カルボニレーション / イソクマリン / ラクトン化 Less

Synthetic studies on bioactive compounds using palladium catalyzed CO insertion
- Principal Investigator
  
  Makabe Hidefumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Shinshu University
Analysis of Photoresponse Genes of Mushroom Mycelia and Correlation with Primary Metabolites
- Principal Investigator
  
  KOJIMA Masanobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Shinshu University
Molecular modeling of anti-amyloidal catechol derivatives using amyloidogenic proteins
- Principal Investigator
  
  NAKAMURA Soichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shinshu University
Functional analysis of fatty acid-binding proteins (FABPs) involved in nuclear receptor signalingPrincipal Investigator
- Principal Investigator
  
  FUJII Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Shinshu University
Molecular modeling of food-grade compounds with anti-conformational disease effects by using amyloidogenic proteins
- Principal Investigator
  
  NAKAMURA Soichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shinshu University
Analysis for anti-inflammatory and anti-fibrotic actions of lipid transfer proteins and lipid-activated transcription factors in the progressive renal injury
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
Analysis of regulation of nuclear receptor-mediated signal transdidian by the ligand-specific transportersPrincipal Investigator
- Principal Investigator
  
  FUJII Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Shinshu University
  Niigata University
A study of searching the growth cone proteins involved in synapse formation
- Principal Investigator
  
  IGARASHI Michihiro
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Investigation on anti-inflammatory effects of lipid-binding proteins and lipophilic transcriptional factors in progression of renal injury.
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
プロテオミクスによる成長円錐からシナプス終末への分子過程の解明
- Principal Investigator
  
  IGARASHI Michihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Investigation on anti-inflammatory effects of lipid-binding proteins in progression of renal injury.
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Faculty of Medical Sciences, University of Fukui
Studies on Novel Nuclear Receptor-mediated Signal TransductionPrincipal Investigator
- Principal Investigator
  
  FUJII Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  NIIGATA UNIVERSITY
BIOCHEMICAL AND HISTOCHEMICAL EXAMINATIONS ON LIPJD-BINDING PROTEINS (LBP), PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) AND RETINOL RECEPTORS (RXR) IN KIDNEY.
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  FACULTY OF MEDICINE FUKUI MEDICAL UNIVERSITY
Cholesterol biosynthesic enzymes and inborn errors
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University
BIOCHEMICAL AND HISTOCHEMICAL EXAMINATIONS ON LIPID-BINDING PROTEINS IN RAT AND HUMAN KIDNEY
- Principal Investigator
  
  KIMURA Hideki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  FACULTY OF MEDICINE,FUKUI MEDICAL UNIVERSITY
Structure and Regulation of Cholesterol Biosynthesis
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University
Cellular Signal Transduction by IsoprenoidsPrincipal Investigator
- Principal Investigator
  
  FUJII Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Niigata University
Regulatory mechanism of Enzymes of Cholesterol Biosynthesis
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Niigata University
REGULATION OF SQUALENE EPOXIDASE EXPRESSION AND THE ENZYME EVOLUTION
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  NIIGATA UNIVERSITY
Studies n Functional Roles of Fatty Acid-Binding Proteins
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Niigata University
REGULATION OF SQUALENE EPOXIDASE EXPRESSION AND THE ENZYME EVOLUTION
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Niigata University
DEVELOPMENT OF SERUM-FABP ASSAY AND IT'S CLINICAL APPLICATION
- Principal Investigator
  
  ONO Teruo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  NIIGATA UNIVERSITY

All 2015 2013 2012 2011 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent

[Journal Article] Makabe Syntheses of prodelphinidin B3 and C2, and their antitumor activities through cell cycle arrest and caspase-3 activation.2013
- Author(s)
  W. Fujii, K. Toda, K. Kawaguchi, S. Kawahara, M. Katoh, Y. Hattori, H. Fujii, H.
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Pages: 3543-3550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Syntheses of prodelphinidin B3 and C2, and their antitumor activities through cell cycle arrest and caspase-3 activation.2013
- Author(s)
  W. Fujii, K. Toda, K. Kawaguchi, S. Kawahara, M. Katoh, Y. Hattori, H. Fujii, H. Makabe
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Pages: 3543-3550
- NAID
  120007106201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Makabe Synthesis of procyanidin C2 & C1 using Lewis acid mediated equimolar condensation.2012
- Author(s)
  Y. Oizumi, M. Katoh, Y. Hattori, K. Toda, K. Kawaguchi, H. Fujii, and H.
- Journal Title
  
  Heterocycles
  
  Volume: 85 (9) Pages: 2241-2250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Synthesis of procyanidin C2 & C1 using Lewis acid mediated equimolar condensation.2012
- Author(s)
  Y. Oizumi, M. Katoh, Y. Hattori, K. Toda, K. Kawaguchi, H. Fujii, and H. Makabe
- Journal Title
  
  Heterocycles
  
  Volume: 85 Pages: 2241-2250
- NAID
  120007106196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Effects of light wavelength and intensity on the expression of photoresponse genes in oyster mushroom mycelia.2011
- Author(s)
  Y. Nakano, H. Fujii, M. Kojima
- Journal Title
  
  J. Light & Visual Environment
  
  Volume: 35 (1) Pages: 90-94
- NAID
  10028106653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Development of a high-specificity sandwich ELISA system for the quantificaion of human intestinal fatty acid-binding protein (I-FABP) concentrations.2011
- Author(s)
  H. Funaoka, T. Kanda, S. Kajiura, Y. Ohkaru, and H. Fujii
- Journal Title
  
  Immunological Investigation
  
  Volume: 40(1) Pages: 1-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Hatakeyama Diagnosis of ischemic small bowel disease by measurement of serum intestinal fatty acid-binding protein in patients with acute abdomen: a multicenter, observer-blinded validation study.2011
- Author(s)
  T. Kanda, A. Tsukahara, K. Ueki, Y. Sakai, T. Tani, A. Nishimura, T. Yamazaki, Y. Tamiya, T. Tada, M. Hirota, J. Hasegawa, H. Funaoka, H. Fujii, K.
- Journal Title
  
  J. Gastroenterology
  
  Volume: 46 Pages: 492-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Diagnosis of ischemic small bowel disease by measurement of serum intestinal fatty acid-binding protein in patients with acute abdomen : a multicenter, observer-blinded validation study2011
- Author(s)
  T.Kanda, A.Tsukahara, K.Ueki, Y.Sakai, T.Tani, A.Nishimura, T.Yamazaki, Y.Tamiya, T.Tada, M.Hirota, J.Hasegawa, H.Funaoka, H.Fujii, K.Hatakeyama
- Journal Title
  
  J.Gastroenterol.
  
  Volume: 46 Pages: 492-500
- DOI
  10.1007/s00535-011-0373-2
- NAID
  10029028597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Effects of light wavelength and intensity on the expression of photoresponse genes in oyster mushroom mycelia2011
- Author(s)
  Y.Nakano, H.Fujii, M.Kojima
- Journal Title
  
  J.Light & Visual Environment
  
  Volume: 35 Pages: 90-94
- NAID
  10028106653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Development of a high-specificity sandwich ELISA system for the quantificaion of human intestinal fatty acid-binding protein(I-FABP)concentrations.2011
- Author(s)
  H.Funaoka, TKanda, S.Kajiura, Y.Ohkaru, H.Fujii
- Journal Title
  
  Immunological Investigation
  
  Volume: 40 Pages: 1-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Light stimulation triggered expression of gene coding for vacuolar proton-pump enzymes v-ATPase and v-PPase in buck wheat.2010
- Author(s)
  M.Kojima, Y.Nakano, H.Fujii
- Journal Title
  
  Biosci.Biotechnol.Biochem.
  
  Volume: 74 Pages: 1507-1511
- NAID
  10027557708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Identification of blue-light photoresponse genes in oyster mushroom mycelia.2010
- Author(s)
  Y.Nakano, H.Fujii, M.Kojima
- Journal Title
  
  Biosci.Biotechnol.Biochem.
  
  Volume: 74 Pages: 2160-2165
- NAID
  10027561046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Identification of blue-light photoresponse genes in oyster mushroom mycelia2010
- Author(s)
  Y. Nakano, H. Fujii, M. Kojima
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 74 Pages: 2160-2165
- NAID
  10027561046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] Light stimulation triggered expression of gene coding for vacuolar proton-pump enzymes v-ATPase and v-PPase in buckwheat.2010
- Author(s)
  M. Kojima, Y. Nakano, H. Fujii
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 74 (7) Pages: 1507-1511
- NAID
  10027557708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570112
[Journal Article] A novel method for RNA interference in neurons using EGFP-transgenic rats2008
- Author(s)
  Lu J, Nozumi M, Fujii H, Igarashi M
- Journal Title
  
  Neurosci Res 61
  
  Pages: 219-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023019
[Journal Article] A novel method for RNA interference in the neuron using enhanced Green fluorescent protein (EGFP)-transgenic rat2008
- Author(s)
  Lu J, Nozumi M, Fujii H, Igarashi M
- Journal Title
  
  Neurosci Res 未定(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023019
[Journal Article] A natural PPAR-γ agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions2008
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Takahashi N, Fujii H, Ishihara S and Yoshida H
- Journal Title
  
  Nephrol Dialysis Transplant 23
  
  Pages: 2496-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] A novel method for RNA interference using EGFP-transgenic rats2008
- Author(s)
  Lu, J., Nozumi, M., Fujii, H., Igarashi, M.
- Journal Title
  
  Neurosci. Res 61
  
  Pages: 219-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17023019
[Journal Article] Establishment and characterization of mono- and polyclonal antibodies to human intestinal fatty acid-binding protein.2007
- Author(s)
  Kajiura, S., Funaoka, H., Ookaru, T., Nishikura, H., Ajioka, Y, Fujii, H., Igarashi, M., Kanda, T., Hatakeyama, K.
- Journal Title
  
  Clin. Chem. Lab. Med. (印刷中)
- Data Source
  KAKENHI-PROJECT-17023019
[Journal Article] Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor-γ in human proximal renal tubular cells2007
- Author(s)
  Li X, Kimura H, Hirota K, Sugimoto H, Kimura N, Takahashi N, Fujii H, Yoshida H
- Journal Title
  
  Nephrol Dialysis Transplant 22
  
  Pages: 1041-1051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590944
[Journal Article] 核内オーファン受容体による胆汁酸代謝制御機構2006
- Author(s)
  藤井博
- Journal Title
  
  医学のあゆみ・消化器疾患 3
  
  Pages: 10-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Journal Article] Regulation of bile acid metabolism mediated by nuclear orphan receptors2006
- Author(s)
  H. Fujii
- Journal Title
  
  Igakuno Ayumi 3
  
  Pages: 10-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Journal Article] Expression of liver-type fatty-acid-binding protein, fatty acid synthase and vascular endothelial growth factor in human lung carcinoma.2005
- Author(s)
  Kawamura T, Kanno R, Fujii H, Suzuki T.
- Journal Title
  
  Pathobiology 72(5)
  
  Pages: 233-240
- Data Source
  KAKENHI-PROJECT-17023019
[Journal Article] Urinary excretion of fatty acid-binding protein reflects stress overload on the proximal tubules.2004
- Author(s)
  Kamijo A, Sugaya T, Hikawa, Fujii H, Fukamizu A, Kimura K. (他7名)
- Journal Title
  
  Am J Pathol. 165(4)
  
  Pages: 1243-1255
- Data Source
  KAKENHI-PROJECT-15029218
[Journal Article] Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor -4 mediates bile acid-induced repression of the human angiotensinogen gene.2004
- Author(s)
  Shimamoto Y, Ishida J, Nangaku M, Xamagata K, Fujii H, Fukamizu A.
- Journal Title
  
  J Biol Chem. 279(9)
  
  Pages: 7770-7776
- Data Source
  KAKENHI-PROJECT-15029218
[Journal Article] Expression of heart-type FABP in human gastric carcinoma and its association with tumor aggressiveness, metastasis and poor prognosis.2004
- Author(s)
  Hashimoto T, Kusakabe T, Kimura H, Fujii H, Suzuki T. (他6名)
- Journal Title
  
  Pathobiology 71(5)
  
  Pages: 267-273
- Data Source
  KAKENHI-PROJECT-15029218
[Patent] 糸状菌から有用代謝産物を生産する方法2012
- Inventor(s)
  小嶋政信・藤井博
- Industrial Property Rights Holder
  信州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-08-06
- Overseas
- Data Source
  KAKENHI-PROJECT-24580106
[Patent] 血中腸型脂肪酸結合蛋白測定による急性腸炎診断2007
- Inventor(s)
  神田達夫、藤井博、船岡宏幸、梶浦聡、大軽晴彦
- Industrial Property Rights Holder
  国立大学法人新潟大学、大日本住友製薬株式会社
- Industrial Property Number
  平19-074164
- Filing Date
  2007-03-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Presentation] キノコ菌糸含有抗腫瘍活性物質並びに癌転移関連遺伝子発現抑制物質の探索2015
- Author(s)
  三浦竜平・小嶋政信・藤井博
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学津島キャンパス
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-24580106
[Presentation] ヒラタケ菌糸に青色光刺激を与えて抗癌活性物質を生産する2013
- Author(s)
  三浦竜平・戸田一弥・藤井博・小嶋政信・三原聡・市村昌紀
- Organizer
  第13回糸状菌分子生物学コンファレンス
- Place of Presentation
  つくば国際会議場
- Data Source
  KAKENHI-PROJECT-24580106
[Presentation] 大腸癌細胞におけるヒト核内受容体FXRの機能解析2012
- Author(s)
  川村悠気, 藤井博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト前立腺癌細胞における転移原因遺伝子FABP5の発現制御機構の解析2012
- Author(s)
  川口耕一郎、木滑歩、鈴木俊介、藤井博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 転移原因遺伝子FABP5 を標的とした抗腫瘍性分子の探索とその作用機構の解析 Identification and Characterization of a Novel Anti-tumorigenic Molecule Using the Metastasis-promoting Gene, FABP5, as a Molecular Target.2012
- Author(s)
  戸田一弥, 川口耕一郎、藤井渉、真壁秀文、藤井博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 青色光刺激を与えてキノコ菌糸の代謝経路を制御する2012
- Author(s)
  小嶋政信、藤井博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト FABP5 遺伝子による癌の転移能獲得機構の解析 Functional Analysis of Acquisition Mechanism of Prostate Cancer Metastasis Mediated by Human FABP52012
- Author(s)
  落合晋太郎, 川口耕一郎、藤井博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Functional Analysis of the Farnesoid X receptor in Colorectal Cancer 大腸癌細胞における核内受容体 FXR の機能解析2012
- Author(s)
  川村悠気, 藤井博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト前立腺癌細胞における FABP5 遺伝子の発現制御機構の解析 Analysis of Regulatory Mechanisms of FABP5 Gene Expression in Human Prostate Cancer2012
- Author(s)
  川口耕一郎、木滑歩、鈴木俊介、藤井博
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 転移原因遺伝子FABP5を分子標的とした抗腫瘍性分子の同定と作用機構の解2012
- Author(s)
  戸田一弥, 川口耕一郎、藤井渉、真壁秀文、藤井博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 青色光刺激を与えてキノコ菌糸の代謝経路を制御する2012
- Author(s)
  小嶋　政信、藤井　博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト前立腺癌細胞におけるSIRT1の機能解析2011
- Author(s)
  吉田満, 藤井博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Characterization of metastasis-inducing gene, C-FABP/FABP5, overexpressed in human prostate cancer cells.2011
- Author(s)
  川口耕一郎, 藤井博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Analysis of the mechanism of prostatic cancer metastasis mediated by human epidermal-type fatty scid-binding protein (C-FABP/FABP5)2011
- Author(s)
  川口耕一郎, 藤井博
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会館(京都)(口頭)(ポスター)
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 大腸癌細胞における核内受容体FXRの機能解析2011
- Author(s)
  川村悠気, 藤井博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Analysis of the mechanism of prostatic cancer metastasis mediated by human epidermal-type fatty acid-binding protein (C-FABP/FABP5).2011
- Author(s)
  川口耕一郎, 藤井博
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト前立腺癌細胞におけるSIRT1の機能解析2011
- Author(s)
  吉田満, 藤井博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Characterization of metastasis-inducing gene, C-FABP/FABP5, overexpressed in human prostate cancer cells2011
- Author(s)
  川口耕一郎, 藤井博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 大腸癌細胞における核内受容体FXRの機能解析2011
- Author(s)
  川村悠気, 藤井博
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Functional analysis of cancer promoting gene, human C-FABP/FABP5, in prostatecancer cells2010
- Author(s)
  Koichiro Kawaguti, Hiroshi Fujii
- Organizer
  第83回日本生化学会・第33回日本分子生物学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Functional analysis of cancer promoting gene, human C-FABP/FABP5, in prostate cancer cells2010
- Author(s)
  Koichiro Kawaguti, Hiroshi Fujii
- Organizer
  第83回日本生化学会・第33回日本分子生物学会合同年会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト上皮型脂肪酸結合タンパク質C-FABP/FABP5による癌の転移能獲得機構の解析2007
- Author(s)
  藤井博
- Organizer
  第80回日本生化学会・第30回分子生物学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Presentation] Analysis of mechanism of human epidermal-type fatty acid-binding protein (C-FABP/FABP5)-induced cancer metastasis2007
- Author(s)
  H. Fujii
- Organizer
  The 80th J. Biochem. Soc. & The 30th J. Mol. Biology Soc
- Place of Presentation
  Yo Kohama
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Presentation] Functional analysis of C-FABP/FABP5 involved in the metastasis of some human cancers2006
- Author(s)
  H. Fujii
- Organizer
  The 20th International Congress of Biochemistry & Mol. Biol. & 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Presentation] Functional analysis of C-FABP/FABP5 involved in the metastasis of some human cancers.2006
- Author(s)
  H. Fujii
- Organizer
  The 20th International Congress of Biochemistry & Molecular Biology & 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570104
[Presentation] 青色光刺激を与えてキノコ菌糸の代謝経路を制御する
- Author(s)
  小嶋政信・藤井博
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24580106
[Presentation] ヒト前立腺癌細胞における転移原因遺伝子FABP5の発現制御機構の解析
- Author(s)
  川口　耕一郎、木滑　歩、鈴木　俊介、藤井　博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 転移原因遺伝子FABP5を分子標的とした抗腫瘍性分子の同定と作用機構の解析
- Author(s)
  戸田　一弥、川口　耕一郎、藤井　渉、真壁　秀文、藤井　博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 大腸癌細胞におけるヒト核内受容体FXRの機能解析
- Author(s)
  川村　悠気、藤井　博
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] Functional Analysis of the Farnesoid X receptor in Colorectal Cancer 大腸癌細胞における核内受容体FXRの機能解析
- Author(s)
  川村　悠気、藤井　博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒト前立腺癌細胞におけるFABP5遺伝子の発現制御機構の解析　Analysis of Regulatory Mechanisms of FABP5 Gene Expression in Human Prostate Cancer
- Author(s)
  川口　耕一郎、木滑　歩、鈴木　俊介、藤井　博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] ヒトFABP5遺伝子による癌の転移能獲得機構の解析　Functional Analysis of Acquisition Mechanism of Prostate Cancer Metastasis Mediated by Human FABP5
- Author(s)
  落合晋太郎、川口　耕一郎、藤井　博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112
[Presentation] 転移原因遺伝子FABP5を標的とした抗腫瘍性分子の探索とその作用機構の解析Identification and Characterization of a Novel Anti-tumorigenic Molecule Using the Metastasis-promoting Gene, FABP5, as a Molecular Target.
- Author(s)
  戸田　一弥、川口　耕一郎、藤井　渉、真壁　秀文、藤井　博
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22570112

1. ONO Teruo (00000927)

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2. SAKAKIBARA Jun (90242403)

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9. IGARASHI Michihiro (50193173)

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10. SUGAYA Takeshi (40381561)

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11. NAKAMURA Soichiro (00105305)

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Fujii Hiroshi 藤井 博

FUJII HIROSHI 藤井 博

FUJII Hiroshi 藤井 博

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Functional analysis of fatty acid-binding proteins (FABPs) involved in nuclear receptor signalingPrincipal Investigator

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Analysis of regulation of nuclear receptor-mediated signal transdidian by the ligand-specific transportersPrincipal Investigator

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Studies on Novel Nuclear Receptor-mediated Signal TransductionPrincipal Investigator

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Fujii Hiroshi 藤井博

FUJII HIROSHI 藤井博

FUJII Hiroshi 藤井博