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Watanabe Michitoshi  渡部 通寿

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… Alternative Names

WATANABE Michitoshi  渡部 通寿

渡辺 通寿  ワタナベ ミチトシ

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Researcher Number 40303127
External Links
Affiliation (Current) 2020: 東北大学, 大学病院, 学術研究員
Affiliation (based on the past Project Information) *help 2015: 東北大学, 大学院薬学研究科, 助教
2014 – 2015: 東北大学, 薬学研究科(研究院), 助教
2007 – 2009: 新潟大学, 医歯学系, 助教
2005 – 2006: 新潟大学, 医歯学系, 助手
2001 – 2004: 新潟大学, 大学院・医歯学総合研究科, 助手
1999 – 2000: Niigata University, School of Medicine, Research Associate, 医学部, 助手
Review Section/Research Field
Principal Investigator
Functional biochemistry
Except Principal Investigator
Biological Sciences / General medical chemistry / Medical pharmacy / Neurochemistry/Neuropharmacology
Keywords
Principal Investigator
ミオシンV / シンタキシン / 膜融合装置 / 開口放出 / カルシウム / 神経伝達 / AFM / BIAcore
Except Principal Investigator
シンタキシン / 成長円錐 … More / カルシウム / ミオシンV / リン酸化 / 開口放出 / ノックインマウス / プロテオミクス / SNARE機構 / 原子間力顕微鏡 / カルモジュリン / 核内レセプター / オキシステロール / LXR / プロテオーム解析 / 蛋白キナーゼ / 開口分泌 / 微小管 / 表面プラズモン共鳴 / SCG10 / アクチン調節蛋白質 / 小胞輸送 / 神経細胞 / RNAi / 神経極性形成 / コンドロイチン硫酸 / 遺伝子改変マウス / GAP-43 / 骨端軟骨 / プロテオーム / 脂肪酸結合蛋白質 / 免疫染色 / インタラクトミクス / 血液脳関門 / トランスポーター / 定量プロテオミクス / P-糖蛋白 / 可塑性 / 病態 / P-糖タンパク / P-glycoprotein / 標的絶対定量プロテオミクス / Pharmacoproteomics / 輸送担体 / 細胞内情報伝達系 / 脳疾患 / スクアレンエポキシダーゼ(SE) / Langer-Giedeon症候群 / 転写調節 / ステロールレギュレトリーエレメント(SRE) / SE機能ドメイン / スクアレンエポ キシダーゼ(SE) / Squalene Epoxidase (SE) / Langer-Giedion Syndrome / Transcriptional Regulation / Sterol Regulatroy Element (SRE) / SE Functional Domain / Intranuclear Receptor / Oxysterol / スクアレンエポキシダーゼ / コレステロール / 酸化ステロール / 核内レヤプター / 転写制御 / スクアレン・エポキシダーゼ(SE) / ヌクレアーオーファンレセプター(LXR,FXR,RXR) / 核内レセプター結合エレメント(LXRE,FXRE) / 24(s),25-epoxycholesterol / Lanosterol Synthase(LS) / I-BABP / squalene epoxidase / cholesterol / oxysterol / nuclear receptor / transcriptional regulation / 構造解析 / シナプス伝達 / Syntaxin / Calmodulin / Myosin-V / Exocytosis / SNARE mechanism / Calcium / Knock-in mice / Structural analysis Less
  • Research Projects

    (9 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (18 People)
  •  Clarification of molecular mechanisms of the blood-brain barrier plasticity based on quantitative targeted absolute proteomics

    • Principal Investigator
      Terasaki Tetsuya
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  A study of searching the growth cone proteins involved in synapse formation

    • Principal Investigator
      IGARASHI Michihiro
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  カルモジュリン結合蛋白質によるシンタキシン機能のCa^<2+>依存性制御の解析

    • Principal Investigator
      五十嵐 道弘
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  プロテオミクスによる成長円錐からシナプス終末への分子過程の解明

    • Principal Investigator
      五十嵐 道弘
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  Significance of the binding between syntaxin and CaMKII using the knock-in mice strategy

    • Principal Investigator
      IGARASHI Mchihiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Niigata University
  •  軸索成長円錐のプロテオーム解析

    • Principal Investigator
      IGARASHI Michihiro
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Niigata University
  •  膜融合装置におけるミオシン-Vの機能の解析Principal Investigator

    • Principal Investigator
      渡部 通寿
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Niigata University
  •  Transcriptional Regulation of Cholesterol Biosynthetic Gene by Nuclear Receptors

    • Principal Investigator
      SAKAKIBARA Jun, 小野 輝夫
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      NIIGATA UNIVERSITY
  •  Cholesterol biosynthesic enzymes and inborn errors

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      General medical chemistry
    • Research Institution
      Niigata University

All 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Drebrin attenuates the interaction between actin and myosin-V. Biochem2007

    • Author(s)
      Ishikawa, R., Katoh, K., Takahashi, A., Ooseki, K., Watanabe, M., Igarashi M, Nakamura, A., Kohama, K.
    • Journal Title

      Biophys. Res. Commun 359

      Pages: 398-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] Roles of Calmodulin and Calmodulin-binding proteins in Synaptic Vesicle Recycling during Regulated Exocytosis at Submicromolar Ca^<2+> Concentrations.2007

    • Author(s)
      Igarashi, M., Watanabe, M
    • Journal Title

      Neurosci. Res. (印刷中)

    • NAID

      10024415467

    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] Roles of calmodulin-binding proteins in synaptic vesicle recycling during regulated exocytosis at submicromolar Ca2+ concentrations2007

    • Author(s)
      Igarashi, M., Watanabe, M.
    • Journal Title

      Neurosci. Res 58

      Pages: 226-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] 局所輸送モーターによる開口放出機構.2006

    • Author(s)
      渡部 通寿, 大関 康志
    • Journal Title

      生化学 78(11)

      Pages: 1077-1083

    • NAID

      10019271482

    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] Role of Ser5O Phosphorylation in SCG10 regulation of microtubule depolymerization.2005

    • Author(s)
      Togano T, Kurachi M, Watanabe M, Grenningloh G, Igarashi M
    • Journal Title

      J Neurosci Res 80(5)

      Pages: 475-480

    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] Role of Ser50 Phosphorylation in SCG10 regulation of microtubule depolymerization.2005

    • Author(s)
      Togano T, Kurachi M, Watanabe M, Grenningloh G, Igarashi M
    • Journal Title

      J Neurosci Res 80(5)

      Pages: 475-480

    • Data Source
      KAKENHI-PROJECT-16044216
  • [Journal Article] Myosin-Va regulates exocytosis through Ca2+-dependent binding of syntaxin-1A2005

    • Author(s)
      Watanabe, M., Nomura, K., Ohyama, A., Ishikawa, R., Komiya, Y., Hosaka, Y., Yamauchi, E., Taniguchi, H., Sasakawa, N., Ushiki, T,. Sato, O., Kumakura, K., Ikebe, M., Igarashi M
    • Journal Title

      Mol. Biol. Cell 16

      Pages: 4519-4530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] Myosin-Va regulates exocytosis through the submicromolar Ca^<2+>-dependent binding of syntaxin-1A2005

    • Author(s)
      Watanabe M, Nomura K, Ohyama A, Ishikawa R, Komiya Y, Hosaka K, Yamauchi E, Taniguchi H, Sasakawa N, Kumakura K, Ushiki T, Sato O, Ikebe M, Igarashi M
    • Journal Title

      Mol Cell Biol 16(10)

      Pages: 4519-4530

    • Data Source
      KAKENHI-PROJECT-16044216
  • [Journal Article] Role of Ser50 phosphorylation in SCG10 regulation of microtubule depolymerization2005

    • Author(s)
      Togano T, Kurachi M, Watanabe M, Grenningloh G, Igarashi M
    • Journal Title

      J Neurosci Res (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300123
  • [Journal Article] Role of Ser5O phosphorylation in SCG10 regulation of microtubule depolymerization2005

    • Author(s)
      Togano T, Kurachi M, Watanabe M, Grenningloh G, Igarashi M
    • Journal Title

      J Neurosci Res (印刷中)

    • Data Source
      KAKENHI-PROJECT-15029218
  • [Journal Article] Role of Ser50 phosphorylation in SCG10 regulation of microtubule depolymerization2005

    • Author(s)
      Togano T, Kurachi M, Watanabe M, Grenningloh G, Igarashi M
    • Journal Title

      J Neurosci Res (印刷中)

    • Data Source
      KAKENHI-PROJECT-16044216
  • [Journal Article] Myosin-Va regulates exocytosis thorugh the submicromolar Ca^<2+>-dependent binding of syntaxin-1A2005

    • Author(s)
      Watanabe M, Nomura K, Ohyama A, Ishikawa R, Komiya Y, Hosaka K, Yamauchi E, Taniguchi H, Sasakawa N, Kumakura K, Ushiki T, Sato O, Ikebe M, Igarashi M
    • Journal Title

      Mol Cell Biol 16(10)

      Pages: 4519-4530

    • Data Source
      KAKENHI-PROJECT-17023019
  • [Journal Article] Role of Ser50 phosphorylation in SCG10 regulation of microtubule depolymerization2005

    • Author(s)
      Togano T, Kurachi M, Watanabe M, Grenningloh G, Igarashi M
    • Journal Title

      J Neurosci Res (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300123
  • [Journal Article] Role of Ser 50 phosphorylation in SCG10 regulation of microtubule depolymerizaiton2005

    • Author(s)
      Togano, T., Kurachi, M., Watanabe, M., Grenningloh, G., Igarashi, M
    • Journal Title

      J. Neurosci. Res 80

      Pages: 475-480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17023019
  • [Presentation] 非神経型シンタキシンのミオシン-V結合能の性状解析2008

    • Author(s)
      渡部通寿、大関康志、田口直希, 五十嵐道弘
    • Organizer
      日本分子生物学会、日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-17023019
  • 1.  IGARASHI Michihiro (50193173)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 14 results
  • 2.  FUJII Hiroshi (90165340)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  SAKAKIBARA Jun (90242403)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  ABE Haruki (40018875)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 5.  ONO Teruo (00000927)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TANAKA Kennichi (10126427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAOKA Masato (60271160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NOZUMI Motohiro (00420323)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Terasaki Tetsuya (60155463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TACHIKAWA Masanori (00401810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NAKADA Mitsutoshi (20334774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HAMADA Junichiro (40253752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  UCHIDA Yasuo (70583590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  谷口 寿章 (10257636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  牛木 辰男 (40184999)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  EDWARDS P.A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SHECHTER I
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SCHROEPFER G
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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