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ONO Teruo
小野 輝夫
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Alternative Names
小野 輝夫 オノ テルオ
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Researcher Number
00000927
Affiliation (based on the past Project Information)
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1992 – 1999: 新潟大学, 医学部, 教授
1990: 新潟大学, 医学部, 教授
1987 – 1988: Niigata University Professor, 医学部, 教授
1986: 新大, 医学部, 教授
Review Section/Research Field
Principal Investigator
General medical chemistry
/
Laboratory medicine
/
医薬分子機能学
Except Principal Investigator
Circulatory organs internal medicine
/
Structural biochemistry
Keywords
Principal Investigator
コレステロール / スクアレン・エポキシダーゼ / H-FABP / I-15P / I-FABP / NF-Y / スクアレン・エポキシダーゼ(SE) / D8S508 / 脂肪酸結合蛋白(FABP) / 心筋梗塞
…
More
/ L-FABP / C-FABP / 阻害剤 / スクアレン / 動脈硬化 / 高脂血症 / スクリーニング / バイオセンサー / スクアレンエポキシダーゼ / SRE / 転写調節 / squalene epoxidase / cholesterol / transcriptional regulation / 核内レセプター / オキシステロール / LXR / heart fatty acid binaing ptotein(H-FABP) / liver fatty acid binding protein(L-FABP) / acylcoA synthetase / 脂肪酸結合蛋白 / 心筋 / 肝臓 / 胃 / 胃壁細胞 / 腎臓 / αzu-グロブリン / sterol regulatory element(SRE) / フラビン酵素 / モノオキシゲナーゼ / ラット / sterol regulatory element (SRE) / 酵母 / Squalene Epoxidase / Sterol Regulatory Element(SRE) / Cholesterol / Monooxygenase / Flavoenzyme / Rat / 血清マーカー / Fatty Acid-Binding Protein / Myocardial Infarct / Serum Mark / 糖尿病 / 虚血性腸疾患 / 蛍光脂肪酸プローブ / 脂肪酸 / ステロイド産生臓器 / Fatty Acid-Binding Protein (FABP) / Diabetes Mellitus / Ischaemic Intestinal Diseases / Fluorescent Fatty Acid / ラノステロール合成酵素(LS) / 酵母トランスフォーマント / クローニング / 抗真菌剤 / スクアレン合成酵素(SS) / 生育阻害 / Squalene epoxidase (SE) / Lanosterol synthase (LS) / Yeast transformant / Inhibitor / Cloning / Antifungal drug / Squalene synthase (SS) / Growth inhibition / エポキシダーゼ(SE) / ベンゾフェノン誘導体 / HMG-CoA還元酵素 / LDL-レセプター / 遺伝子発現 / 染色体8q24.13 / squalene epoxidase(SE) / benzophenone derivatives / HMG-CoA reductase / LDL-receptor / gene expression / chromosome 8 q24.13 / ラノステロール合成酵素 / SREBP / 転写因子 / 膜結合領域 / 転写調整 / 遺伝子構造(イントロン-エクソン構成) / HeLa細胞 / 発現調節 / プロモーター領域 / 染色体8 / lanosterol synthase / SREBP (sterol regulatory element binding protein) / transcription factor / membrane binding domain / スクアレンエポキシダーゼ(SE) / Langer-Giedeon症候群 / ステロールレギュレトリーエレメント(SRE) / SE機能ドメイン / スクアレンエポ キシダーゼ(SE) / Squalene Epoxidase (SE) / Langer-Giedion Syndrome / Transcriptional Regulation / Sterol Regulatroy Element (SRE) / SE Functional Domain / Intranuclear Receptor / Oxysterol / 酸化ステロール / 核内レヤプター / 転写制御 / ヌクレアーオーファンレセプター(LXR,FXR,RXR) / 核内レセプター結合エレメント(LXRE,FXRE) / 24(s),25-epoxycholesterol / Lanosterol Synthase(LS) / I-BABP / oxysterol / nuclear receptor / 肝型脂肪酸結合蛋白(L-FABP) / 心筋型脂肪酸結合蛋白(H-FABP) / 脳型脂肪酸結合蛋白(B-FABP) / アシルCoA合成酸素 / ジアシルグリセロールキナーゼ / L-FABP(肝型脂肪酸結合蛋白) / 内因性脂肪酸 / アラキドン酸 / DG-kinase(Diacylglycerol kinase) / Hepatic fatty acid binding protein (L-FABP) / Cardiac fatty acid binding protein (H-FBP) / Brain fatty acid binding protein (B-FABP) / Acyl CoA synthetase
…
More
Except Principal Investigator
ras / 胆嚢 / 粘膜内癌 / 固有筋層浸潤癌 / 漿膜下微少浸潤癌 / 癌の発育・進展 / 患者予後 / 脈管侵襲 / リンパ節転移 / コレステロール / スクアレン・エポキシダーゼ / 遺伝子 / 動脈硬化症 / 阻害薬 / DNAクローニング / コレステロール代謝 / スクアレンエポキシダーゼ / 代謝阻害薬 / cholesterol / squalene epoxidase / gene / atherosclerosis / inhibitors / DNA cloning / 蛋白質の脂質修飾 / 蛋白質のプレニル化 / イソプレノイド / シグナル伝達 / 分子シャペロン / Ras / posttranslational lipid modification / protein modification / isoprenoid / signal transduction / molecular chaperon
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Research Projects
(
14
results)
Co-Researchers
(
28
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Transcriptional Regulation of Cholesterol Biosynthetic Gene by Nuclear Receptors
Principal Investigator
Principal Investigator
SAKAKIBARA Jun
, 小野 輝夫
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
NIIGATA UNIVERSITY
Cholesterol biosynthesic enzymes and inborn errors
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (A).
Research Field
General medical chemistry
Research Institution
Niigata University
Structure and Regulation of Cholesterol Biosynthesis
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General medical chemistry
Research Institution
Niigata University
Cellular Signal Transduction by Isoprenoids
Principal Investigator
FUJII Hiroshi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Structural biochemistry
Research Institution
Niigata University
Regulatory mechanism of Enzymes of Cholesterol Biosynthesis
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Niigata University
Development of A New Cholesterol Lowering Drug to Prevent Atherosclerosis
Principal Investigator
OKAMOTO Hiroshi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Circulatory organs internal medicine
Research Institution
Hokkaido University
REGULATION OF SQUALENE EPOXIDASE EXPRESSION AND THE ENZYME EVOLUTION
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
医薬分子機能学
Research Institution
NIIGATA UNIVERSITY
Studies n Functional Roles of Fatty Acid-Binding Proteins
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Niigata University
REGULATION OF SQUALENE EPOXIDASE EXPRESSION AND THE ENZYME EVOLUTION
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
Niigata University
DEVELOPMENT OF SERUM-FABP ASSAY AND IT'S CLINICAL APPLICATION
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Laboratory medicine
Research Institution
NIIGATA UNIVERSITY
ヒト胆道癌の発生・進展・特性に関する多角的基礎研究
Principal Investigator
渡辺 英伸
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Niigata University
心筋細胞での脂肪酸結合蛋白(FABP)の機能
Principal Investigator
Principal Investigator
小野 輝夫
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Niigata University
心筋細胞での脂肪酸結合蛋白(FABP)の機能
Principal Investigator
Principal Investigator
小野 輝夫
Project Period (FY)
1987
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Niigata University
Molecular species of fatty acid binding protein and their function in lipid metabolism
Principal Investigator
Principal Investigator
ONO Teruo
Project Period (FY)
1985 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
Niigata University
# of Projects (Dsc)
# of Projects (Asc)
1.
SAKAKIBARA Jun
(90242403)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
2.
FUJII Hiroshi
(90165340)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
3.
ODANI Shoji
(60018702)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
KUMAGAI Hidetoshi
(20281008)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
HITOMI Masahiro
(40218730)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
WATANABE Michitoshi
(40303127)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
星野 力
(30165542)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
SCHROEPFER George
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
OKADA Masahiko
(30018915)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
ISEKI Shoichi
(50167251)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
SUZUKI Toshimitsu
(80018952)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
KONDO Hisatake
(20004723)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
OKAMOTO Hiroshi
(50260394)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
KAWAGUCHI Hideaki
(70161297)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
KITABATAKE Akira
(00124769)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
KANOH Hideo
(70045475)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
渡辺 英伸
(70037381)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
木南 凌
(40133615)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
STORCH Judith
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
SHECHTER Ishaiahu
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
PRESTWICH Glenn
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
JUDITH Storc
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
STEIN J.P.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
STEIN Joseph
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
LAW J.A
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
SCHROPFER G.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
EDWARDS P.A.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
SHECHTER I
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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