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KONO Tomohiro  河野 友宏

ORCIDConnect your ORCID iD *help
… Alternative Names

河野 友広  コウノ トモヒロ

河野 友宏  コウノ トモヒロ

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Researcher Number 80153485
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 東京農業大学, 生命科学部, 教授
2000 – 2017: 東京農業大学, 応用生物科学部, 教授
2002: Faculty of Applied Bioscience, Professor, 応用生物化学部, 教授
1996 – 2002: 東京農業大学, 農学部, 教授
2001: 東京農大, 農学部, 教授
1993 – 1995: 東京農業大学, 農学部, 助教授
Review Section/Research Field
Principal Investigator
Applied animal science / Applied animal science / Biological Sciences / Animal production science / Laboratory animal science
Except Principal Investigator
Genetics/Chromosome dynamics / Laboratory animal science / Applied animal science / Laboratory animal science / Applied animal science / Biological Sciences
Keywords
Principal Investigator
核移植 / 遺伝子発現 / ゲノムインプリンティング / 卵母細胞 / 単為発生 / Nuclear transfer / マウス / DNAメチル化 / リプログラミング / 次世代シークエンサー … More / ゲノムインプリント / embryo cloning / クローン / Oocytes / Genomic imprinting / 発生・分化 / 胚発生 / 発生 / エピゲノム / 生殖細胞 / 始原生殖細胞 / トランスクリプトーム / 生殖系列 / メチローム / マイクロアレイ / 性転換マウス / ゲノム編集 / 3Dイメージング / トランスクリプトーム解析 / Sry欠損性転換マウス / 生殖系列細胞 / Sry欠損 / 生殖細胞形成異常 / CRISPR/Cas9 / 性転換 / ChIP-seq / ヒストン修飾 / 性分化 / エピジェネティクス / abnormal development / epigenetic regulation / reprogramming / gene expression analysis / エピジェネティク調節 / 発生異常 / 遺伝子発現解析 / 体細胞クローン / Development / In vitro culture / 体外培養 / 対外培養 / disease model mice / ES cells / mdx mice / dy mice / NOD mice / 糖尿病 / 筋ジストロフィー / DNA methylation / Gene expression / Parthenogenesis / 哺乳動物 / 発現制御 / GENE EXPRESSION / NUCLEAR TRANSFER / DEVELOPMENT / MOUSE / GENOMIC IMPRINTING / インプリンティング / bovine embryos / nuclear transfer / parthenogenesis / mouse embryos / Ca^<2+> / 細胞周期 / ウシ胚 / マウス胚 / カルシウムイオン / バイサルファイトショットガン解析 / イピゲノム / 脱メチル化 / DNAメチローム / DNA メチローム / メチル基転移酵素 / 非コードRNA / メチル化転移酵素 / TGマウス / BACクローン / 非翻訳RNA / 個体発生 / 二母性胚 … More
Except Principal Investigator
核移植 / クローン動物 / 性決定機構 / W染色体 / mitochondria / embryonic stem cells / nuclear transfer / cloned mice / experimental animals / ヘテロプラスミー / ミトコンドリア / ES細胞 / 実験動物 / EMBRYO TRANSFER / CO-CULTURE / PARTHENOGENETIC ACTIVATION / SERIAL NUCLEAR TRANSFER / CLONE CATTLE / NUCLEAR TRANSFER / 細胞周期 / 胚移植 / 共培養 / 単為発生刺激 / 継代核移植 / クローン牛 / リプロフラミング因子 / リプログラミング因子 / 発生工学 / リプログラミング / 再生医療 / 発生・分化 / 雌核発生胚 / 雄核発生胚 / CHIP on chip / 胎盤進化 / 胎盤由来幹細胞 / ゲノムインプリント / メチル化 / 比較ゲノム / アレル特異的メチル化領域 / 胎盤幹(TS)細胞 / ゲノムインプリンテング Less
  • Research Projects

    (17 results)
  • Research Products

    (206 results)
  • Co-Researchers

    (27 People)
  •  Sex specification of germline cells by epigenetic regulation in micePrincipal Investigator

    • Principal Investigator
      Kono Tomohiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Animal production science
    • Research Institution
      Tokyo University of Agriculture
  •  Identification of a sex-determining gene in Emu

    • Principal Investigator
      Kuroiwa Asato
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Genetics/Chromosome dynamics
    • Research Institution
      Hokkaido University
  •  Comprehensive analysis of egg-specific reprograming factors based on cell cycle-specific localization

    • Principal Investigator
      SOTOMARU YUSUKE
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Hiroshima University
  •  Analysis of Epigenome Marks and Transcriptome in the Germ Line by the Next Generation SequencerPrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture
  •  次世代シークエンサーを用いた生殖細胞におけるエピゲノム修飾の全ゲノムマッピングPrincipal Investigator

    • Principal Investigator
      河野 友宏
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture
  •  Establishment of pluripotent stem cells from trophoblast stem cells

    • Principal Investigator
      OGAWA Hidehiko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture
  •  胎盤幹細胞を用いた胎盤進化プロセスと哺乳類特異的ゲノムインプリント機構の解析

    • Principal Investigator
      有馬 隆博
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Regulation of germ line function and development by genome imprintingPrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Agriculture
  •  Regulation of germ line function and development by genomic imprintingPrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture
  •  Studies on developmental aberration of somatic clones by global gene expression analysisPrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture
  •  Control of epigenetic modification for oocytes genomePrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied animal science
    • Research Institution
      TOKYO UNIVERSITY OF AGRICULTURE
  •  Practical use of cloning technology for NOD and dy disease model mice productionPrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      TOKYO UNIVERSITY OF AGRICULTURE
  •  Mechanism for Developmental Regulation by Genomic Imprinting in the Female Germ Line.Principal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Agriculture
  •  Generation of cloned mice and application on the field of laboratory animal science

    • Principal Investigator
      ITO Mamoru
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  STUDIES ON REGULATION OF DEVELOPMENT BY GENOMIC IMPRINTINGPrincipal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied animal science
    • Research Institution
      TOKYO UNIVERSITY OF AGRICULTURE
  •  哺乳動物胚の初期発生における細胞内カルシウムイオンの役割Principal Investigator

    • Principal Investigator
      KONO Tomohiro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied animal science
    • Research Institution
      Tokyo University of Agriculture
  •  STUDIES ON DEVELOPMENT OF PRACTICAL TECHNIQUE FOR PRODUCING CLONE COWS BY NUCLEAR TRANSFER

    • Principal Investigator
      NAKAHARA Tatsuo
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Applied animal science
    • Research Institution
      TOKYO UNIVERSITY OF AGRICULTURE

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 卵子学2011

    • Author(s)
      河野友宏
    • Publisher
      京都大学学術出版会
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Book] 卵子発育とゲノムインプリンティング,「卵子学」2011

    • Author(s)
      河野友宏, 他
    • Publisher
      京都大学学術出版会
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Book] 生命の誕生に向けて<第二版>生殖補助医療(ART)胚培養の理論と実際2011

    • Author(s)
      河野友宏
    • Publisher
      近代出版
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Book] 生命の誕生に向けて<第二版>生殖補助医療(ART)胚培養の理論と実際2011

    • Author(s)
      河野友宏
    • Publisher
      近代出版
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Book] 卵子学2011

    • Author(s)
      河野友宏
    • Publisher
      京都大学学術出版会
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Book] 生殖系列細胞のプログラム, 「生命の誕生にむけて」2010

    • Author(s)
      河野友宏,他
    • Publisher
      近大出版
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] DNA Methylation Errors in Cloned Mouse Sperm by Germ Line Barrier Evasion2016

    • Author(s)
      Koike T, Wakai T, Jincho Y, Sakashita A, Kobayashi H, Mizutani E, Wakayama S, Miura F, Ito T, Kono T
    • Journal Title

      Biol Reprod

      Volume: 94 Issue: 6 Pages: 1-7

    • DOI

      10.1095/biolreprod.116.138677

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02472, KAKENHI-PROJECT-15H05579, KAKENHI-PROJECT-26506006, KAKENHI-PROJECT-26250038
  • [Journal Article] Cell proliferation potency is independent of FGF4 signaling in trophoblast stem cells derived from androgenetic embryos2016

    • Author(s)
      Ogawa H, Takyu R, Morimoto H, Toei S, Sakon H, Goto S, Moriya S, Kono T.
    • Journal Title

      J. Reprod. Dev.

      Volume: 62 Issue: 1 Pages: 51-58

    • DOI

      10.1262/jrd.2015-097

    • NAID

      130005126319

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25450470, KAKENHI-PROJECT-25860398, KAKENHI-PROJECT-15H02472, KAKENHI-PROJECT-16K19187
  • [Journal Article] Complete in vitro generation of fertile oocytes from mouse primordial germ cells2016

    • Author(s)
      Morohaku K, Tanimoto R, Sasaki K, Kawahara-Miki R, Kono T, Hayashi K, Hirao Y, Obata Y.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 113 Issue: 32 Pages: 9021-9026

    • DOI

      10.1073/pnas.1603817113

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25114008, KAKENHI-PROJECT-15H02472, KAKENHI-PROJECT-26450449
  • [Journal Article] Repetitive DNA methylome analysis by small-scale and single-cell shotgun bisulfite sequencing.2016

    • Author(s)
      Kobayashi H, Koike T, Sakashita A, Tanaka K, Kumamoto S, Kono T
    • Journal Title

      Genes Cells

      Volume: 21 Issue: 11 Pages: 1209-1222

    • DOI

      10.1111/gtc.12440

    • NAID

      130007024787

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02472, KAKENHI-PROJECT-15H05579, KAKENHI-PROJECT-15J08690
  • [Journal Article] Sex Specification and Heterogeneity of Primordial Germ Cells in Mice.2015

    • Author(s)
      Sakashita, A., Kawabata, Y., Jincho, Y., Tajima, S., Kumamoto, S., Kobayashi, H., Matsui, Y. and Kono, T.
    • Journal Title

      PLoS ONE

      Volume: 10 Issue: 12 Pages: 1-21

    • DOI

      10.1371/journal.pone.0144836

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25114003, KAKENHI-PROJECT-15H02472, KAKENHI-PROJECT-15H05579, KAKENHI-PROJECT-15J08690, KAKENHI-PROJECT-25650104
  • [Journal Article] Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting2014

    • Author(s)
      Hara S, Takano T, Fujikawa T, Yamada M, Wakai T, Kono T, Obata Y
    • Journal Title

      Hum Mol Genet

      Volume: 23(10) Issue: 14 Pages: 1-12

    • DOI

      10.1093/hmg/ddu100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22228004, KAKENHI-PROJECT-23616006, KAKENHI-PLANNED-25114008, KAKENHI-PROJECT-26450449
  • [Journal Article] Dynamics of genomic 5-hydroxymethylcytosine during mouse oocyte growth2014

    • Author(s)
      Akihito Sakashita, Hisato Kobayashi, Takuya Wakai, Yuusuke Sotomaru, Kenichiro Hata, Tomohiro Kono
    • Journal Title

      Genes Cells

      Volume: 19 Issue: 8 Pages: 629-636

    • DOI

      10.1111/gtc.12164

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22228004, KAKENHI-PROJECT-25640051, KAKENHI-PROJECT-25870766
  • [Journal Article] DNAメチル化情報として生殖細胞に記憶される性差2014

    • Author(s)
      河野友宏
    • Journal Title

      岩波科学

      Volume: 84 Pages: 773-778

    • Data Source
      KAKENHI-PROJECT-22228004
  • [Journal Article] Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia.2013

    • Author(s)
      Obata Y, Wakai T, Hara S, Kono T.
    • Journal Title

      Reproduction

      Volume: 147(1) Pages: 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Journal Article] Epigenetic and transcriptional features of the novel human imprinted lncRNA GPR1AS suggest it is a functional ortholog to mouse Zdbf2linc.2013

    • Author(s)
      Kobayashi H, Yanagisawa E, Sakashita A, Sugawara N, Kumakura S, Ogawa H, Akutsu H, Hata K, Nakabayashi K, Kono T.
    • Journal Title

      Epigenetics

      Volume: 8 (6) Issue: 6 Pages: 635-645

    • DOI

      10.4161/epi.24887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22228004, KAKENHI-PROJECT-25450470, KAKENHI-PROJECT-25460409, KAKENHI-PROJECT-25870766
  • [Journal Article] Mouse oocyte methylomes at base resolution reveal genome- wide accumulation of non-CpG methylation and role of DNA methyltransferases2013

    • Author(s)
      Shirane K, Toh H, Kobayashi H, Miura F, Chiba H, Ito T, Kono T, Sasaki H
    • Journal Title

      PLoS Genet

      Volume: 9(4) Issue: 4 Pages: 303-306

    • DOI

      10.1371/journal.pgen.1003439

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009, KAKENHI-PLANNED-20062010, KAKENHI-PROJECT-22228004, KAKENHI-PROJECT-23590657, KAKENHI-PUBLICLY-25129702, KAKENHI-PROJECT-25870766
  • [Journal Article] The transcriptomic architecture of mouse Sertoli cell clone embryos reveals temporal.spatial-specific reprogramming2013

    • Author(s)
      Cao F, Fukuda A, Watanabe H, Kono T
    • Journal Title

      Reproduction

      Volume: 145(3) Pages: 277-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells2012

    • Author(s)
      Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K
    • Journal Title

      Nature

      Volume: 13;465(7295) Issue: 7295 Pages: 175-181

    • DOI

      10.1038/nature09017

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Imprinted DNA methylation reprogramming during early mouse embryogenesis at the Gpr1-Zdbf2 locus is linked to long cis-intergenic transcription2012

    • Author(s)
      Kobayashi H, Sakurai T, Sato S, Nakabayashi K, Hata K, Kono T
    • Journal Title

      FEBS Lett

      Volume: 23;586(6) Issue: 6 Pages: 827-833

    • DOI

      10.1016/j.febslet.2012.01.059

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009, KAKENHI-PROJECT-221S0002
  • [Journal Article] Porcine nuclei in early growing stage do not possess meiotic competence in matured oocytes2012

    • Author(s)
      Ogawa H, Matsuzaki T, Yamamoto A, Kashiwazaki N, Kono T
    • Journal Title

      Theriogenology

      Volume: 78(3) Issue: 3 Pages: 560-566

    • DOI

      10.1016/j.theriogenology.2012.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks2012

    • Author(s)
      Kobayashi H, Sakurai T, Imai M, Takahashi N, Fukuda A, Yayoi O, Sato S, Nakabayashi K, Hata K, Sotomaru Y, Suzuki Y, Kono T
    • Journal Title

      PLoS Genet

      Volume: 8(1) Issue: 1 Pages: e1002440-e1002440

    • DOI

      10.1371/journal.pgen.1002440

    • NAID

      120005300482

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009, KAKENHI-PROJECT-22390328, KAKENHI-PROJECT-24249084, KAKENHI-PROJECT-221S0002
  • [Journal Article] Epigenetically immature oocytes lead to loss of imprinting during embryogenesis2011

    • Author(s)
      Obata Y, Hiura H, Fukuda A, Komiyama J, Hatada I, Kono T
    • Journal Title

      J Reprod Dev

      Volume: 57(3) Pages: 327-334

    • NAID

      10029050351

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] 卵子形成とエピジェネティクス2010

    • Author(s)
      河野友宏
    • Journal Title

      HORMONE FRONTIER IN GYNECOLOGY

      Volume: 5 Pages: 335-340

    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Identification of inappropriately reprogrammed genes by large-scale transcriptome analysis of individual cloned mouse blastocysts.2010

    • Author(s)
      Fukuda, Atsushi, Kono, Tomohiro
    • Journal Title

      PLoS One 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Identification of inappropriately reprogrammed genes by large-scale transcriptome analysis of individual cloned mouse blastocysts2010

    • Author(s)
      Fukuda A, Cao F, Morita S, Yamada K, Jincho Y, Tane S, Sotomaru Y, Kono T
    • Journal Title

      PLoS One

      Volume: 30;5(6) Issue: 6 Pages: e11274-e11274

    • DOI

      10.1371/journal.pone.0011274

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells.2010

    • Author(s)
      Stadtfeld, Matthias, Kono, Tomohiro
    • Journal Title

      Nature 465

      Pages: 175-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] 卵子形成とエピジェネティクス2010

    • Author(s)
      河野友宏
    • Journal Title

      HORMONE FRONTIER IN GYNECOLOGY

      Volume: 5 Pages: 335-340

    • Data Source
      KAKENHI-PROJECT-22228004
  • [Journal Article] Longevity in mice without a father.2010

    • Author(s)
      Kawahara, Manabu, Kono, Tomohiro.
    • Journal Title

      Human Reprod 25

      Pages: 457-461

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Restoration of Dlk1 and Rtl1 is necessary but insufficient to rescue of the lethality in IG-DMR deficient mice.2010

    • Author(s)
      Takahashi, Nozomi.Kono, Tomohiro
    • Journal Title

      J Biol Chem 285

      Pages: 26121-26125

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] A tripartite paternally methylated region within the Gprl-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip2010

    • Author(s)
      Hiura H, Sugawara A, Ogawa H, John RM, Miyauchi N, Miyanari Y, Horiike T, Li Y, Yaegashi N, Sasaki H, Kono T, Arima T.
    • Journal Title

      Nucleic Acids Research (未定, in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20017003
  • [Journal Article] Longevity in mice without a father2010

    • Author(s)
      Kawahara M, Kono T
    • Journal Title

      Hum Reprod

      Volume: 25(2) Issue: 2 Pages: 457-461

    • DOI

      10.1093/humrep/dep400

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Restoration of Dlk1 and Rtl1 is necessary but insufficient to rescue lethality in intergenic differentially methylated region (IG-DMR)- deficient mice2010

    • Author(s)
      Takahashi N, Kobayashi R, Kono T
    • Journal Title

      J Biol Chem

      Volume: 285(34) Issue: 34 Pages: 26121-26125

    • DOI

      10.1074/jbc.m109.075325

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origindependent defects in mice2009

    • Author(s)
      Takahashi, N., Sotomaru, Y.,Kono, T. 他5名
    • Journal Title

      Human Molecular Genetics 18

      Pages: 1879-1888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin- dependent defects in mice2009

    • Author(s)
      Takahashi N, Okamoto A, Kobayashi R, Shirai M, Obata Y, Ogawa H, Sotomaru Y, Kono T
    • Journal Title

      Hum Mol Genet

      Volume: 15;18(10) Pages: 1879-1888

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Developmental ability of trophoblast stem cells in uniparental mouse embryos2009

    • Author(s)
      Ogawa H, Shindo N, Kumagai T, Usami Y, Shikanai M, Jonwn K, Fukuda A, Kawahara M, Sotomaru Y, Tanaka S, Arima T, Kono T
    • Journal Title

      Placenta

      Volume: 30(5) Issue: 5 Pages: 448-456

    • DOI

      10.1016/j.placenta.2009.02.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Defining contributions of paternally methylated imprinted genes at the IGF2-H19 and DLK1-GTl2 domains to mouse placentation by transcriptomic analysis.2009

    • Author(s)
      Kawahara, Manabu., Kono, Tomohiro., 他2名
    • Journal Title

      Journal of Biological Chemistry Published online on April 20

    • NAID

      120006377532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice.2009

    • Author(s)
      Takahashi, Nozomi, Obata, Yayoi, Kono, Tomohiro, et al.
    • Journal Title

      Human Mol Genet 18

      Pages: 1879-1888

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Defining contributions of paternally methylated imprinted genes at the Igf2-H19 and Dlk1-Gtl2 domains to mouse placentation by transcriptomic analysis2009

    • Author(s)
      Kawahara M, Morita S, Takahashi N, Kono T
    • Journal Title

      J Biol Chem

      Volume: 284(26) Pages: 17751-17765

    • NAID

      120006377532

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Genetic modification for bimaternal embryo development2009

    • Author(s)
      Kono, Tomohiro
    • Journal Title

      Reproduction, Fertility and Development 21

      Pages: 31-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Defining contributions of paternallymethylated imprinted genes at the IGF2-H19 and DLK1-GTl2 domains tomouse placentation by transcriptomicanalysis2009

    • Author(s)
      Kawahara, M., Kono, T. 他2名
    • Journal Title

      Jornal of Biological Chemistry(published online on April 20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Defining contributions of paternally methylated imprinted genes at the IGF2-H19 and DLKJ-GT12 domains to mouse placentation by transcriptomic analysis2009

    • Author(s)
      Kawahara, Manabu., Kono, Tomohiro, 他2名
    • Journal Title

      Journal of Biological Chemistry (Published online on April 20)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Developmental ability of trophoblast stem cells in uniparental mouse embryos2009

    • Author(s)
      Ogawa, H., Sotomaru, Y., Kono, T. 他9名
    • Journal Title

      Placenta 30

      Pages: 448-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Developmental ability of trophoblast stem cells in uniparental mouse embryos.2009

    • Author(s)
      Ogawa, Hidehiko., Sotomaru, Yusuke., Kono, Tomohiro., 他9名
    • Journal Title

      Placenta 30

      Pages: 448-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] ほ乳類の単為発生2009

    • Author(s)
      河野友宏
    • Journal Title

      最新医学 64

      Pages: 104-116

    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice.2009

    • Author(s)
      Takahashi, Nozomi., Sotomaru, Yusuke., Kono, Tomohiro., 他5名
    • Journal Title

      Human Molecular Genetics 18

      Pages: 1879-1888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Developmental ability of trophoblast stem cells in uniparental mouse embryos2009

    • Author(s)
      Ogawa, Hidehiko., Kono, Tomohiro, 他8名
    • Journal Title

      Placenta 30

      Pages: 448-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Developmental ability of trophoblast stem cells in uniparental mouse embryos2009

    • Author(s)
      Ogawa H, Shindo N, Kumagai T, Usami Y, Shikanai M, Jonwn K, Fukuda A, Kawahara M, Sotomaru Y, Tanaka S, Arima T, Kono T.
    • Journal Title

      Placenta 30

      Pages: 448-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20017003
  • [Journal Article] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 22009

    • Author(s)
      Kobayashi, Hisato., Kono, Tomohiro, 他8名
    • Journal Title

      Genomics 93

      Pages: 461-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 2.2009

    • Author(s)
      Kobayashi, Hisato., Sotomaru, Yusuke., Kono, Tomohiro., 他7名
    • Journal Title

      Genomics 93

      Pages: 461-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] 「かぐやシスターズ」の誕生からみえてきた父母ゲノムの役割2009

    • Author(s)
      河野友宏
    • Journal Title

      Biophilia 5

      Pages: 34-48

    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 22009

    • Author(s)
      Kobayashi, H., Sotomaru, Y., Kono, T. 他7名
    • Journal Title

      Genomics 93

      Pages: 461-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Deletion of Gt12, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice2009

    • Author(s)
      Takahashi, Nozomi., Obata, Yayoi., Ogawa, Hidehiko., Kono, Tomohiro, 他4名
    • Journal Title

      Human Molecular Genetics 18

      Pages: 1879-1888

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Genetic modification for bimatemal embryo development.2009

    • Author(s)
      Kono, Tomohiro.
    • Journal Title

      Reproduction, Fertility and Development 21

      Pages: 31-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Defining contributions of paternally methylated imprinted genes at the Igf2-H19 and Dlk1-Gtl2 domains to mouse placentation by transcriptomic analysis.2009

    • Author(s)
      Kawahara, Manabu, Kono Tomohiro
    • Journal Title

      J Biol Chem 284

      Pages: 17751-17765

    • NAID

      120006377532

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 22009

    • Author(s)
      Kobayashi H, Yamada K, Morita S, Hiura H, Fukuda A, Kagami M, Ogata T, Hata K, Sotomaru Y, Kono T
    • Journal Title

      Genomics

      Volume: 93(5) Issue: 5 Pages: 461-47

    • DOI

      10.1016/j.ygeno.2008.12.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009, KAKENHI-PLANNED-20062010
  • [Journal Article] Genetic modification for bimaternal embryo development2009

    • Author(s)
      Kono, T
    • Journal Title

      Reproduction, Fertility and Development 21

      Pages: 31-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Protocol for the production of viable bimaternal mouse embryos2008

    • Author(s)
      Kawahara, M., Sotomaru , Y., Kono T. 他5名
    • Journal Title

      Nature protocols 3

      Pages: 197-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] 二母性マウスの開発2008

    • Author(s)
      河野友宏
    • Journal Title

      細胞工学 27

      Pages: 812-819

    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Protocol for the production of viable bimaternal mouse embryos2008

    • Author(s)
      Kawahara M, Obata Y, Sotomaru Y, Shimozawa N, Bao S, Tsukadaira T, Fukuda A, Kono T
    • Journal Title

      Nat Protoc

      Volume: 3(2) Issue: 2 Pages: 197-209

    • DOI

      10.1038/nprot.2007.531

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] Protocol for the production of viable bimatemal mouse embryos.2008

    • Author(s)
      Kawahara, Manabu., Sotomaru, Yusuke., Kono Tomohiro., 他5名
    • Journal Title

      Nature protocols 3

      Pages: 197-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] 二母性マウスの開発2008

    • Author(s)
      河野 友宏
    • Journal Title

      細胞工学 27

      Pages: 812-819

    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Protocol for the production of viable bimaternal mouse embryos2008

    • Author(s)
      Kawahara, Manabu., Kono Tomohiro, 他6名
    • Journal Title

      Nature protocols 3

      Pages: 197-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Journal Article] ゲノムインプリンティングと二母性マウスの開発2008

    • Author(s)
      川原 学, 河野 友宏
    • Journal Title

      化学と生物 46

      Pages: 452-459

    • NAID

      10024333917

    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] High-frequency generation of viablemice from engineered bi-maternal embryos2007

    • Author(s)
      Kawahara,M., Kono, T. 他6名
    • Journal Title

      Nature biotechnology 25

      Pages: 1045-1050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Long-term effects of in vitro growth of mouse oocytes on their maturation and development2007

    • Author(s)
      Obata Y, Kono T, 他2名
    • Journal Title

      Journal of Reproduction and Development 53・6

      Pages: 1183-1190

    • NAID

      10020172629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Appropriate expression of imprinted genes on mouse chromosome 12 extends development of bi-maternal embryos to term2007

    • Author(s)
      Kawahara M, Kono T, 他2名
    • Journal Title

      FEBS Letters 581

      Pages: 5178-5184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Appropriate expression of imprinted genes on mouse chromosome 12 extends development of bi-maternal embryos to term2007

    • Author(s)
      Kawahara, M., Kono, T. 他2名
    • Journal Title

      FEBS Letters 581

      Pages: 5178-5184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] High frequency generation of viable mice from engineered bi-maternal embryos2007

    • Author(s)
      Kawahara M, Kono T, 他6名
    • Journal Title

      Nature Biotechnology 25・9

      Pages: 1045-1050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] DNA methylation imprints on the IG-DMR of the Dlk1-Gtl2domain in mouse male germline2007

    • Author(s)
      Hiura, H., Kono, T. 他4名
    • Journal Title

      FEBS Letters 581

      Pages: 1255-1260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] DNA methylation imprints on the IG-DMR of the Dlk1-Gt12 domain in mouse male germline2007

    • Author(s)
      Hiura H, Kono T, 他4名
    • Journal Title

      FEBS Letters 25・9

      Pages: 1255-1260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Long-termeffects of In vitro growth of mouseoocytes on their maturation anddevelopment2007

    • Author(s)
      Obata, Y., Kono,T. 他2名
    • Journal Title

      Journal of reproduction and development 53

      Pages: 183-1190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Isolation,characterization,and invitro and in vivo differentiation ofputative thecal stem cells2007

    • Author(s)
      Honda, A., Kono, T., 他10名
    • Journal Title

      PNA 104

      Pages: 12389-12394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Isolation, characterization, and in vitro and in vivo differentiation of putative thecal stem cells2007

    • Author(s)
      Honda A, Kono T, 他10名
    • Journal Title

      PNAS 104・30

      Pages: 12389-12394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Regulated expressions of two sets of paternally imprinted genes is necessary for mouse parthenogenetic development to term2006

    • Author(s)
      Wu, Q., Kono, T. 他6名
    • Journal Title

      Reproduction 131

      Pages: 481-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Genomic imprinting is a barrier to parthenogenesis in mammals.2006

    • Author(s)
      Kono T
    • Journal Title

      Cytogenetic and Genome Research 131

      Pages: 31-35

    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Complementary roles of genes regulated by two paternally methylated imprinted regions on chromosomes 7 and 12 in mouseplacentation2006

    • Author(s)
      Kawahara, M., Kono, T. 他3名
    • Journal Title

      Human Molecular Genetics 15

      Pages: 2869-2879

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Oocyte growth-dependent progression of maternal imprinting in mice2006

    • Author(s)
      Hiura, H., Kono, T. 他3名
    • Journal Title

      Genes to Cells 11

      Pages: 353-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Disruption of parental-specific expression of imprinted genes in uniparental fetuses2006

    • Author(s)
      Ogawa, H., Kono, T. 他3名
    • Journal Title

      FEBS Letters 580

      Pages: 5377-5384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Regulated expressions of two sets of paternally imprinted genes are necessary for mouse parthenogenetic development to term.2006

    • Author(s)
      Wu Q, Kumagai T, Kawahara M, Ogawa H, Hiura H, Obata Y, Takano R, Kono T.
    • Journal Title

      Reproduction 131

      Pages: 481-488

    • Data Source
      KAKENHI-PROJECT-16380192
  • [Journal Article] The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice2006

    • Author(s)
      Arima, T., Kono, T. 他6名
    • Journal Title

      Genomics 88

      Pages: 650-658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Genomic imprinting is a barrier to parthenogenesis in mammals. Cytogenet2006

    • Author(s)
      Kono, T
    • Journal Title

      Genome Research 113

      Pages: 31-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Journal Article] Pluripotential competence of cells associated with nanog activity.2005

    • Author(s)
      Hatano S, Tada M, Kimura H, Yamaguchi S, Kono T, Nakano T, Suemori H, Nakatsuji N, Tada T.
    • Journal Title

      Mechanisms of Dev. 122

      Pages: 67-79

    • Data Source
      KAKENHI-PROJECT-16380192
  • [Journal Article] Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation.2005

    • Author(s)
      Sato A, Kono T, Nakada K, Ishikawa K, Inoue S, Yonekawa H, Hayashi J.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 102

      Pages: 16765-16770

    • Data Source
      KAKENHI-PROJECT-16380192
  • [Journal Article] Rapid replacement of somatic linker histones with the oocyte-specific linker histone H1foo in nuclear transfer.2004

    • Author(s)
      Teranishi T, Tanaka M, Kimoto S, Kono T, Yoshimura Y, et al.
    • Journal Title

      Dev.Biol. 266

      Pages: 78-86

    • Data Source
      KAKENHI-PROJECT-16380192
  • [Journal Article] Nuclei of oocytes derived from mouse parthenogenetic embryos are competent to support development to term.2004

    • Author(s)
      Niwa K, Takano R, Obata Y, Ogawa H, Kono T. et al.
    • Journal Title

      Biol Reprod. 71

      Pages: 1560-1567

    • Data Source
      KAKENHI-PROJECT-16380192
  • [Journal Article] Oocyte growth-dependent progression of maternal imprinting in mice.

    • Author(s)
      Hiura H, Obata Y, Komiyama J, Shirai M, Kono T.
    • Journal Title

      Genes to Cells (In press)

    • Data Source
      KAKENHI-PROJECT-16380192
  • [Patent] 核移植卵、単為発生胚および単為発生非ヒト哺乳動物の作出方法2012

    • Inventor(s)
      河野友宏、川原学
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Acquisition Date
      2012-09-07
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] METHOD OF CONSTRUCTING NUCLEUS-IMPLANTED EGG,PARTHENOGENETIC EMBRYO AND PARTHENOGENETIC MAMMAL2010

    • Inventor(s)
      河野友宏、尾畑やよい、川原学
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Acquisition Date
      2010-02-09
    • Overseas
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 特許権2010

    • Inventor(s)
      河野友宏, 尾畑やよい, 川原学
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Filing Date
      2010-02-09
    • Overseas
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 特許権2009

    • Inventor(s)
      河野友宏, 尾畑やよい
    • Industrial Property Rights Holder
      東京農業大学
    • Acquisition Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Patent] 特許権2009

    • Inventor(s)
      河野友宏, 尾畑やよい
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Filing Date
      2009-02-25
    • Overseas
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 核移植卵、単為発生胚および単為発生哺乳動物の作出法2009

    • Inventor(s)
      河野友宏、尾畑やよい
    • Industrial Property Rights Holder
      東京農業大学
    • Acquisition Date
      2009-03-21
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Patent] 核移植卵、単為発生胚および単為発生哺乳動物の作出方法2009

    • Inventor(s)
      河野友宏、尾畑やよい
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Acquisition Date
      2009-03-13
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] METHOD OF CONSTRUCTING NUCLEAR-TRANSPLANTED EGG,PARTHENOGENETIC EMBRYO AND PARTHENOGENETIC MAMMAL2009

    • Inventor(s)
      河野友宏、尾畑やよい
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Acquisition Date
      2009-02-25
    • Overseas
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 特許権2009

    • Inventor(s)
      河野友宏, 尾畑やよい
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Filing Date
      2009-03-13
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] Method of Constructing Nuclear-Transplanted Egg, Parthenogenetic Embryo and Parthenogenetic Mammal2009

    • Inventor(s)
      河野友宏、尾畑やよい
    • Industrial Property Rights Holder
      東京農業大学
    • Acquisition Date
      2009-02-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Patent] 特許権2009

    • Inventor(s)
      河野友宏, 尾畑やよい
    • Industrial Property Rights Holder
      東京農業大学
    • Acquisition Date
      2009-02-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Patent] METHOD OF CONSTRUCTING NUCLEUS-IMPLANTED EGG,PARTHENOGENETIC EMBRYO AND PARTHENOGENETIC MAMMAL2008

    • Inventor(s)
      河野友宏、尾畑やよい、川原学
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Filing Date
      2008-06-18
    • Overseas
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 核移植卵、単為発生胚および単為発生非ヒト哺乳動物の作出方法2007

    • Inventor(s)
      河野友宏、川原学
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Industrial Property Number
      2007-171707
    • Filing Date
      2007-06-29
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 核移植卵、単為発生胚および単為発生哺乳動物の作出方法2007

    • Inventor(s)
      河野友宏, 川原学
    • Industrial Property Rights Holder
      東京農業大学
    • Industrial Property Number
      2007-171707
    • Filing Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Patent] METHOD OF CONSTRUCTING NUCLEAR-TRANSPLANTED EGG,PARTHENOGENETIC EMBRYO AND PARTHENOGENETIC MAMMAL2004

    • Inventor(s)
      河野友宏、尾畑やよい
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Filing Date
      2004-08-04
    • Overseas
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Patent] 核移植卵、単為発生胚および単為発生哺乳動物の作出方法2004

    • Inventor(s)
      河野友宏、尾畑やよい
    • Industrial Property Rights Holder
      学校法人東京農業大学
    • Industrial Property Number
      2005-512613
    • Filing Date
      2004-08-04
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Single-cell transcriptome analysis in XY oocytes of SRY-mutated, sex-reversed mice2017

    • Author(s)
      Akihiko SAKASHITA, Chiaki NISHIMURA, Tomohiro Kono
    • Organizer
      World Congress of Reproductive Biology 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] Sry欠損XY性転換雌マウスの卵母細胞成熟能および繁殖能の解析2017

    • Author(s)
      西村千秋, 坂下陽彦, 河野友宏
    • Organizer
      第58回 日本卵子学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] ホールマウント免疫染色法を用いたPGCsの計数とアポトーシスの検出2016

    • Author(s)
      田島紫雲、井関陽介、小川英彦、尾畑やよい、河野友宏
    • Organizer
      日本卵子学会
    • Place of Presentation
      新潟県、新潟市、ときメッセ
    • Year and Date
      2016-05-14
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] DNA methylome analysis in mouse germ cells and early embryos2016

    • Author(s)
      Tomohiro Kono, Hisato Kobayashi, Tasuku Koike, Akihiko Sakashita, Haruka Tsuno, Soichiro Kumamoto, Takuya Wakai, Satoshi Sano
    • Organizer
      ESHRE
    • Place of Presentation
      Finland, Helsinki, Mussukeskus
    • Year and Date
      2016-07-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] XY oocytes of sex-reversed mice with Sry mutation deviate from the differentiation process at initial stages2016

    • Author(s)
      Akihiko SAKASHITA, Chiaki NISHIMURA, Hisato KOBAYASHI, Yusuke SOTOMARU, Tomohiro KONO
    • Organizer
      分子生物学会
    • Place of Presentation
      神奈川県、横浜、パシフィコ横浜
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] 脱メチル化完了後のマウス始原生殖細胞におけるヒストン修飾の役割2016

    • Author(s)
      川畑順子、神尾明日香、神長祐子、高島友弥、坂下陽彦、小林久人、河野友宏
    • Organizer
      分子生物学会
    • Place of Presentation
      神奈川県、横浜、パシフィコ横浜
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] マウス生殖細胞および初期発生胚のDNAメチローム解析2016

    • Author(s)
      小林 久人、小池 佐、坂下 陽彦、都能 遼、隈本 宗一郎、若井 拓也、佐野 賢、河野 友宏
    • Organizer
      分子生物学会
    • Place of Presentation
      神奈川県、横浜、パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] これからの生殖医療技術とその安全・安心 -遺伝子解析技術の進歩2015

    • Author(s)
      河野友宏
    • Organizer
      岡大ARTセンターシンポジウム
    • Place of Presentation
      岡山大学
    • Year and Date
      2015-01-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] Regulation of Gender Specific Gene Expression in mouse Primordial Germ Cells2015

    • Author(s)
      Akihiko Sakashita, Yukiko Kawabata, Yuko Jincho, Shiun Tajima, Souichiro Kumamoto, Hisato Kobayashi, Yasuhisa Matsui, Tomohiro Kono
    • Organizer
      Epigenetics 2015
    • Place of Presentation
      Tasmania, Australia
    • Year and Date
      2015-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] マウス始原生殖細胞の遺伝子発現を制御するエピゲノム修飾2015

    • Author(s)
      神長祐子, 川畑順子, 坂下陽彦, 小林久人、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      宮崎大学
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] マウス始原生殖細胞におけるDNAメチル化非依存的な性特異的遺伝子発現機構2015

    • Author(s)
      坂下 陽彦, 田島 紫雲, 川畑 順子, 神長 裕子, 小林 久人, 河野 友宏
    • Organizer
      日本卵子学会
    • Place of Presentation
      宇都宮
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15H02472
  • [Presentation] 体細胞クローンマウス精子のDNAメチレーションエラー2014

    • Author(s)
      河野友宏, 若井拓也, 水谷英二, 小林久人, 若山清香, 坂下陽彦, 三浦史仁, 伊藤隆司
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      帯広畜産大学
    • Year and Date
      2014-09-22
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス生殖細胞・初期胚のDNAメチローム解析2014

    • Author(s)
      小林久人、坂下陽彦、若井拓哉、小池佐、佐野賢、河野友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      横浜国際展示場
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] 体細胞クローンマウス精子のDNAメチル化リプログラミング2014

    • Author(s)
      若井 拓哉、水谷英二、小林久人、若山 清香、坂下 陽彦、伊藤 隆司、 三浦 史仁、河野 友
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜国際展示場
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] 全ゲノムを対象としたメチローム解析が明らかにする雌雄差2014

    • Author(s)
      河野友宏
    • Organizer
      染色体研究会
    • Place of Presentation
      東京医科大学病院
    • Year and Date
      2014-04-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス初期胚における5hmCおよびH3K9me2の挙動とDNA脱メチル化制御機構2014

    • Author(s)
      坂下 陽彦、中島 芽生、若井 拓哉、小林 久人、井関陽介、河野 友宏
    • Organizer
      本哺乳動物卵子学会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2014-05-17
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] Genome-wide reprogramming by DNA demethylation during mouse oocyte growth and early development2014

    • Author(s)
      Akihiko SAKASHITA, Yosuke ISEKI, Mei NAKAJIMA, Takuya WAKAI, Hisato KOBAYASHI, Tomohiro KONO
    • Organizer
      World Congress of Reproductive Biology
    • Place of Presentation
      Edinburgh (UK)
    • Year and Date
      2014-09-03
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス12番染色体非コードインプリント遺伝子の過剰発現モデルにおける表現型解析2013

    • Author(s)
      藤原真、高橋望、平田裕、外丸祐介、河野友宏
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25640051
  • [Presentation] マウス卵子形成過程における5-hydroxymethylcytosine のダイナミクス2013

    • Author(s)
      坂下陽彦、小林久人、井関陽介、若井拓哉、外丸祐介、河野友宏
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25640051
  • [Presentation] 着床前クローン胚発生において異常発現遺伝子の染色体マップ2012

    • Author(s)
      曹峰,福田篤,渡辺大士,河野友宏
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Methylomes and transcriptomes in mouse germ cells.2011

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      Fertility 2011
    • Place of Presentation
      アイルランド
    • Year and Date
      2011-01-07
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Methylomes and transcriptomes in mouse germ cells2011

    • Author(s)
      Tomohiro Kono
    • Organizer
      Fertility 2011
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2011-01-07
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] DNAメチローム解析による生殖系列のリプログラミング評価2011

    • Author(s)
      河野友宏
    • Organizer
      第56回日本生殖医学会学術講演会・総会
    • Place of Presentation
      パシフィコ横浜(招待講演)
    • Year and Date
      2011-12-08
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス配偶子における全ゲノム包括的 DNAメチローム解析2011

    • Author(s)
      小林久人,河野友宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Methylomes and transcriptomes in mouse germ cells2011

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      Fertility 2011
    • Place of Presentation
      アイルランド・ダブリン
    • Year and Date
      2011-01-07
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス雌核発生胚の胚盤胞期胚における内部細胞塊および栄養外胚葉における網羅的遺伝子発現解析2011

    • Author(s)
      小川英彦,後藤詩織,岸靖典,曹峰,河野友宏
    • Organizer
      第104回日本繁殖生物学会大会
    • Place of Presentation
      いわて県民情報交流センター
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] DNAメチローム解析による生殖系列のリプログラミング評価2011

    • Author(s)
      河野友宏
    • Organizer
      第56回日本生殖医学会学術講演会・総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-08
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 核移植における栄養膜幹細胞ゲノムの全能性再獲得能の評価2011

    • Author(s)
      渡邊紘之、小川英彦、河野友宏
    • Organizer
      第52回日本哺乳動物卵子学会
    • Place of Presentation
      国際医療福祉大学
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-22658084
  • [Presentation] Bisulphite Shotgun Sequencing法によるマウス生殖細胞の包括的 DNAメチル化解析2010

    • Author(s)
      小林久人,桜井隆順,福田篤,高橋望,尾畑やよい,中林一彦,秦健一郎,外丸佑介,鈴木穣,河野友宏
    • Organizer
      第33回分子生物学会(BMB2010)
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 着床前マウスクローン胚におけるトランスクリプトーム解析2010

    • Author(s)
      曹 峰,福田 篤,岸 靖典,河野 友宏
    • Organizer
      第33回分子生物学会(MB2010)
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Methylomes and transcriptomes in mouse germ cell2010

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      International Symposium on "Epigenome Network, Devel opment and Reprogramming of Germ Cells"
    • Place of Presentation
      九州大学医学部百年講堂(福岡市)
    • Year and Date
      2010-11-24
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] Genetic modification for bi-maternal embryo development2009

    • Author(s)
      河野友宏
    • Organizer
      the International Embryo Transfer Society
    • Place of Presentation
      米国
    • Year and Date
      2009-01-05
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 二母性マウスの長命性について2009

    • Author(s)
      河野友宏
    • Organizer
      第102回日本繁殖生物学会
    • Place of Presentation
      近畿大学農学部
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] The regulation of imprinted gene2009

    • Author(s)
      Tomohiro Kono
    • Organizer
      From imprinting to the Epigenome in 25 years
    • Place of Presentation
      University of Cambridge, England
    • Year and Date
      2009-09-06
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 二母性マウスの長命性について2009

    • Author(s)
      河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      近畿大学
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 二母性マウス胚由来胎盤における網羅的遺伝子発現解析2009

    • Author(s)
      川原学,森田慎之助,高橋望,河野友宏
    • Organizer
      第102回日本繁殖生物学会
    • Place of Presentation
      近畿大学農学部
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Genetic modification for bi-maternal embryo development2009

    • Author(s)
      Kono, Tomohiro
    • Organizer
      Annual Conference of the International Embryo Transfer Society
    • Place of Presentation
      SanDiego, USA
    • Year and Date
      2009-01-05
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 非コードインプリント遺伝子Gtl2欠損マウスの親特異的な致死性と分子制御機構2009

    • Author(s)
      高橋望,小林亮太,岡本晶,山口瑛人,河野友宏
    • Organizer
      第102回日本繁殖生物学会
    • Place of Presentation
      近畿大学農学部
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] The regulation of imprinted gene.2009

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      From imprinting to the Epigenome in 25 years.
    • Place of Presentation
      英国ケンブリッジ大学
    • Year and Date
      2009-09-06
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] The regulation of imprinted gene2009

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      From imprinting to the Epigenome in 25 years
    • Place of Presentation
      ケンブリッジ大学(イギリス国ケンブリッジシャー州)
    • Year and Date
      2009-09-06
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Genetic modification for bi-maternal embryo development2009

    • Author(s)
      Tomohiro Kono
    • Organizer
      35th Annual Conference of the International Embryo Transfer Society
    • Place of Presentation
      SanDiego, USA
    • Year and Date
      2009-01-05
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Genetic modification for bi-matemal embryo development2009

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      Annual Conference of the International Embryo Transfer Society
    • Place of Presentation
      SanDiego, USA
    • Year and Date
      2009-01-05
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Non-codingRNAインプリント遺伝子Glt2欠損マウスにおけるRtl1遺伝子の発現解析2008

    • Author(s)
      小林亮太、河野友宏
    • Organizer
      日本繁殖生物学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Glt2遺伝子欠損マウスにおける器官形成異常2008

    • Author(s)
      岡本晶、河野友宏
    • Organizer
      日本哺乳動物卵子学会大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Generation of viable bimaternal mice lacking a paternal genome2008

    • Author(s)
      河野友宏
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      米国
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Non-coding RNAインプリント遺伝子Glt2欠損マウスにおけるRtl1遺伝子の発現解析2008

    • Author(s)
      小林亮太、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Generation of viable bimaternal mice lacking a paternal genome2008

    • Author(s)
      Kono, Tomohiro
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Hawaii,USA
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 単為発生胚を用いた新規インプリント遺伝子の探索 : マウス1番染色体のZdbf2遺伝子は父由来アレル特異的に発現するインプリント遺伝子である2008

    • Author(s)
      小林 久人, 外丸 祐介, 河野 友宏
    • Organizer
      日本繁殖生物学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Glt2遺伝子欠損マウスにおける器官形成異常2008

    • Author(s)
      岡本 晶, 河野 友宏
    • Organizer
      日本哺乳動物卵子学会大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 非コードインプリント遺伝子Glt2欠損マウスにおける親の特異的な致死性および遺伝子発現異常2008

    • Author(s)
      高橋望、小川英彦、尾畑やよい、河野友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 単為発生胚を用いた新規インプリント遺伝子の探索 : マウス1番染色体のZdbf2遺伝子は父由来アレル特異的に発現するインプリント遺伝子である2008

    • Author(s)
      小林久人、外丸祐介、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 非コードインプリント遺伝子Glt2欠損マウスにおける親の特異的な致死性および遺伝子発現異常2008

    • Author(s)
      高橋望、河野友宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マイクロアレイ法を用いた単一マウスクローン胚盤胞の網羅的遺伝子発現解析2008

    • Author(s)
      曹峰、河野友宏
    • Organizer
      日本繁殖生物学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Non-coding RNA インプリント遺伝子Glt2欠損マウスにおけるRtll遺伝子の発現解析2008

    • Author(s)
      小林 亮太, 河野 友宏
    • Organizer
      日本繁殖生物学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Deletion of the maternally expressed imprinted gene, Gtl2, resulted in parental-specific lethality in mice2008

    • Author(s)
      Nozomi Takahashi, Akira Okamoto, Motomu Shirai, Ryota Kobayashi, Tomohiro Kono
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 非コードインプリント遺伝子 Gtl2欠損マウスにおける親の特異的な致死性および遺伝子発現異常2008

    • Author(s)
      高橋望,岡本晶,小林亮太,白井求,小川英彦,尾畑やよい,河野友宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 非翻訳インプリント遺伝子Glt2欠損マウスにおける致死性および器官形成異常2008

    • Author(s)
      岡本晶、小川英彦、尾畑やよい、河野友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Glt2遺伝子欠損マウスにおける器官形成異常2008

    • Author(s)
      岡本晶、河野友宏
    • Organizer
      日本哺乳動物卵子学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-05-27
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マイクロアレイ法を用いた単一マウスクローン胚盤胞の網羅的遺伝子発現解析2008

    • Author(s)
      曹 峰, 外丸 祐介, 河野 友宏
    • Organizer
      日本繁殖生物学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 単為発生胚を用いた新規インプリント遺伝子の探索 : マウス1番染色体のZdbfZ遺伝子は父由来アレル特異的に発現するインプリント遺伝子である2008

    • Author(s)
      小林久人、河野友宏
    • Organizer
      日本繁殖生物学会大会
    • Place of Presentation
      九州大学
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Deletion of the maternally expressed imprinted gene, Glt2, resulted in parental-specific lethality in mice2008

    • Author(s)
      Takahashi, Nozomi., Kono, Tomohiro
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 非コードインプリント遺伝子Glt2欠損マウスにおける親の特異的な致死性および遺伝子発現異常2008

    • Author(s)
      高橋 望, 河野 友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マイクロアレイ方を用いた単一マウスクローン胚盤胞の網羅的遺伝子発現解析2008

    • Author(s)
      曹峰、外丸祐介、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-18
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Generation of viable bimaternal mice lacking a paternal genome2008

    • Author(s)
      Tomohiro Kono
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] Deletion of the maternally expressed imprinted gene, Glt2, resulted in parental-specific lethality in mice2008

    • Author(s)
      高橋望、河野友宏
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      米国
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Deletion of the maternally expressed imprinted gene, Glt2, resulted in parental-specific lethality in mice2008

    • Author(s)
      Takahashi, Nozomi., Kono, Tomohiro
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 非翻訳インプリント遺伝子Glt2欠損マウスにおける致死性および器官形成異常2008

    • Author(s)
      岡本晶, 河野 友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Generation of viable bimaternal mice lacking a paternal genome.2008

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      米国ハワイ
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 単為発生胚を用いた新規インプリント遺伝子の探索 : マウス1番染色体のZdbf2遺伝子は父由来アレル特異的に発現するインプリント遺伝子である2008

    • Author(s)
      小林久人、外丸祐介、河野友宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 非翻訳インプリント遺伝子Glt2欠損マウスにおける致死性および器官形成異常2008

    • Author(s)
      岡本晶、河野友宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Generation of viable bimatemal mice lacking a paternal genome2008

    • Author(s)
      Kono, Tomohiro.
    • Organizer
      World Congress on Reproductive Biology
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 単為発生胚を用いた新規インプリント遺伝子の探索 : マウス1番染色体のZdbf2遺伝子は父由来アレル特異的に発現するインプリント遺伝子である2008

    • Author(s)
      小林 久人, 外丸 祐介, 河野 友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 単為発生胚を用いた新規インプリント遺伝子の探索 : マウス1番染色体のZdbf2遺伝子は父由来アレル特異的に発現するインプリント遺伝子である2008

    • Author(s)
      小林久人、河野友宏
    • Organizer
      日本分子生物学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PLANNED-20062009
  • [Presentation] 雄の遺伝的関与を欠いたマウスの効率的な生産2007

    • Author(s)
      川原学、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      東京
    • Year and Date
      2007-10-20
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 二母性マウス表現型の特徴2007

    • Author(s)
      河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      東京
    • Year and Date
      2007-10-20
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マイクロアレイ解析を用いたマウス新規インプリント遺伝子の探査2007

    • Author(s)
      山田かおり、外丸祐介、河野友宏
    • Organizer
      日本哺乳動物卵子学会
    • Place of Presentation
      山梨
    • Year and Date
      2007-05-17
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Establishment of trophoblastic stem like cell from mouse parthenogenetic embryos2007

    • Author(s)
      小川英彦、河野友宏
    • Organizer
      International Embryo Transfer Sciety
    • Place of Presentation
      京都
    • Year and Date
      2007-01-06
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Developmental competence of mouse ooytes after in vitro groeth nuclear transfer, and in vitro fertilization2007

    • Author(s)
      尾畑やよい、河野友宏
    • Organizer
      International Embryo Transfer Sciety
    • Place of Presentation
      京都
    • Year and Date
      2007-01-06
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Regulation of mammalian development by genomic imprinting2007

    • Author(s)
      河野友宏
    • Organizer
      International Young Scientist Forum on Mammalian Reproductive Biotechnology
    • Place of Presentation
      中国
    • Year and Date
      2007-08-28
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 父母メチル化インプリントの責務2007

    • Author(s)
      河野友宏
    • Organizer
      日本哺乳動物卵子学会
    • Place of Presentation
      山梨
    • Year and Date
      2007-05-17
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マイクロアレイ解析を用いたマウス新規インプリント遺伝子の探査2006

    • Author(s)
      山田かおり、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マウス父性インプリント遺伝子の精子形成過程におけるDNAメチル化修飾獲得時期の特定2006

    • Author(s)
      白井求、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マウス胎盤形成における7 番染色体および12 番染色体上の父性インプリント遺伝子の役割2006

    • Author(s)
      川原学、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マウスESクローン胚盤胞期における特異的発現遺伝子の網羅的探査2006

    • Author(s)
      神長祐子、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 非コードインプリント遺伝子Gt12欠損マウスの発生解析2006

    • Author(s)
      高橋望、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Complementary roles of Igf2and Dlk1 for descendants2006

    • Author(s)
      河野友宏
    • Organizer
      International Genomic Imprinting Workshop
    • Year and Date
      2006-11-29
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マウス卵母細胞におけるインプリント遺伝子のヒストン修飾解析2006

    • Author(s)
      樋浦仁、河野友宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Genes controlled by two paternally imprinted regions differentiallycontribute to mouse placentation2006

    • Author(s)
      川原学、河野友宏
    • Organizer
      Society for Reproduction and Fertility Conference
    • Place of Presentation
      英国
    • Year and Date
      2006-07-03
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] B6-Y 性転換マウス由来卵母細胞の発生特性2006

    • Author(s)
      尾畑やよい、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Maturation of prcine oocytes reconstructed with a nucleus from the growing stage oocytes2006

    • Author(s)
      松崎隆、河野友宏
    • Organizer
      Society for the Study of Reproduction
    • Place of Presentation
      米国
    • Year and Date
      2006-07-29
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] Effect of lgf2 and Dlk1 genes on hematopoiesis in mouse2006

    • Author(s)
      呉瓊、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] 雄核発生胚および雌核発生胚由来栄養膜幹細胞におけるCdx2 遺伝子の発現2006

    • Author(s)
      小川英彦、河野友宏
    • Organizer
      日本繁殖生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-07
    • Data Source
      KAKENHI-PROJECT-18208024
  • [Presentation] マウス12番染色体非コードインプリント遺伝子の過剰発現モデルに おける表現型解析

    • Author(s)
      藤原真、高橋望,平田裕,外丸祐介, 河野友宏
    • Organizer
      第36回 日本分子生物学会
    • Place of Presentation
      神戸ポートアイランド国際会議場
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] インプリント遺伝子クラスターGPR1-ZDBF2における転写調節・エピジェネティクス制御機構とヒト・マウスゲノム間の類似性

    • Author(s)
      河野友宏
    • Organizer
      特定領域研究「生殖系列の世代サイクルとエピゲノムネットワーク」第5回シンポジウム
    • Place of Presentation
      京都大学医学部構内芝蘭会館
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] DNAメチローム解析によって明らかにされたマウス生殖系列のリプログラミング

    • Author(s)
      河野友宏
    • Organizer
      日本遺伝学会第85回大会ワークショップ
    • Place of Presentation
      慶応義塾大学日吉キャンパス
    • Invited
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス12番染色体非コードインプリント遺伝子の過剰発現モデルにおける表現型解析

    • Author(s)
      藤原真,高橋望,平田裕,外丸祐介, 河野友宏
    • Organizer
      第106回日本繁殖生物学会
    • Place of Presentation
      東京農工大学
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] 生殖系列のリプログラミングはどこまで理解できたか ― 体細胞から生殖系列への転換 ―

    • Author(s)
      河野友宏
    • Organizer
      NIAS/NILGS合同シンポジウム
    • Place of Presentation
      エポカルつくば
    • Invited
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス卵母細胞におけるゲノム刷り込みの分子機構

    • Author(s)
      原 聡史,川原玲香、尾畑やよい、河野友宏
    • Organizer
      第106回日本繁殖生物学会
    • Place of Presentation
      東京農工大学
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] マウス卵子形成過程における5ヒドロキシメチル化シトシンのダイナミクス

    • Author(s)
      坂下陽彦, 小林久人, 井関陽介、若井拓也、外丸祐介、 河野友宏
    • Organizer
      第106回日本繁殖生物学会
    • Place of Presentation
      東京農工大学
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] Amplification-free whole-genome shotgun bisulfite sequencing of mouse primordial germ cells

    • Author(s)
      Kobayashi H, Sakurai T, Miura F, Imai M, Mochiduki K, Yanagisawa E,Sakashita A, Wakai T, Suzuki Y, Ito T, Matsui Y, Kono T.
    • Organizer
      Non-coding RNA, epigenetics and transgenerational inheritance 2013
    • Place of Presentation
      ケンブリッジ、イギリス
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] ARTと生殖系列エピゲノムリプログラミング

    • Author(s)
      河野友宏
    • Organizer
      第10回 東海ARTカンファレンス
    • Place of Presentation
      名古屋市(名鉄ニューグランドホテル)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22228004
  • [Presentation] Dlk1-Dio3ドメインBAC-TGマウスに認められる発生異常

    • Author(s)
      野村圭代、藤原真、高橋望、雉岡めぐみ、隈本 宗一郎、外丸 祐介、河野友宏
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25640051
  • [Presentation] マウス卵子形成過程における5-hydroxymethylcytosine のダイナミク ス

    • Author(s)
      坂下陽彦、小林久人, 井関陽介、若井拓也、外丸祐介、 河野友宏
    • Organizer
      第36回 日本分子生物学会
    • Place of Presentation
      神戸ポートアイランド国際会議場
    • Data Source
      KAKENHI-PROJECT-22228004
  • 1.  SOTOMARU Yusuke (90309352)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 24 results
  • 2.  OBATA Yayoi (70312907)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 3.  OGAWA Hidehiko (20339089)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 4.  SUZUKI Yutaka (40323646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  KOBAYASHI Hisato (70632727)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 19 results
  • 6.  ITO Mamoru (00176364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  IMAI Hiroshi (10303869)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KANDA Akifumi (80512649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HATAKEYAMA Teruhiko (50452595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NAKAHARA Tatsuo (50189015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TSUNODA Yukio (80217364)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HIOKI Kyoji (80208735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TANIOKA Yoshikuni (10072406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHIMOZAWA Norihiro (50300786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NAGAFUCHI Seiko (00150441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MIYANO Takashi (80200195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HATADA Izuho (50212147)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  Kuroiwa Asato (20372261)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  有馬 隆博 (80253532)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 20.  松田 洋一 (70165835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  西田 千鶴子 (50106580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YOSHIOKA Miyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TAKANO Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  AONO Fumihito
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SEKIZAWA Fumio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  HIRAO Yuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  松居 靖久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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