Nishizawa Masatoyo 西澤正豊

… Alternative Names

NISHIZAWA Masatoyo 西澤正豊

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Researcher Number	80198457
Other IDs
External Links
Affiliation (Current)	2025: 新潟医療福祉大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help	2004 – 2015: 新潟大学, 脳研究所, 教授 2003 – 2004: 新潟大学, 医学部, 教授 2000: International University of Health and Welfare, Dept. Neurology, Professor, 教授 1999: International University of Health and Welfare, Department of Health Science, Professor, 保健学部, 教授 1998: 自治医科大学, 医学部・神経内科, 助教授 … More 1996 – 1998: 自治医科大学, 医学部, 助教授 1994 – 1995: 自治医科大学, 助教授 1991 – 1994: 自治医科大学, 医学部, 助教授 1990: 国立精神, 神経センター・神経研究所・疾病研究第6部, 室長 1989: Natl.Inst.Neurosci., NCNP, Section Chief, 神経研究所・疾病研究第6部, 室長 1988: 国立精神・神経センター, 神経研究所・疾患研究第6部・室 Less
Review Section/Research Field	Principal Investigator Neurology / Biological Sciences / Neurology Except Principal Investigator Neurology / Neurology / Neuroscience in general / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 脊髄小脳変性症 / 1本鎖DNA損傷修復 / triplet repeat / anticipation / 運動失調症 / 分子病態 / アプラタキシン欠損症 / 劣性遺伝 / EAOH / Chimera mouse … More / Animal model / Down syndrome / Alzheimer's disease / Trisomy 16 mouse / コリン作動性ニューロン / キメラ / マウストリソミー16 / 痴呆 / アルツハイマー病 / キメラマウス / 動物モデル / ダウン症 / アルツハイマ-病 / トリソミ-16マウス / microtubulus organizing center / neuronal cell death / aggregate formation / polyglutamine / CAG repeat / 細胞死 / 微小管形成センター / 微少*形成センター / 神経細胞死 / 凝集体 / ポリグルタミン / CAGリピート / gene analysis / molecular genetics / chromosome 14 / Machado-Joseph disease / 遺伝子座 / 連鎖解析 / Machado-Joseph病 / 遺伝子診断 / triplet-repeat / 分子遺伝学 / 第14染色体 / Machado-Joseph / degeneration / neuronal hybridoma / cell fusion / cerebellum / 神経細胞株 / 小脳変性症 / 神経ハイブリドーマ細胞株 / 細胞融合 / 小脳 / 神経病態 / 筋萎縮性側索硬化症 / Cajal小体 / 核内小体 / SMN / U12 snRNA / TDP-43 / GEM / ALS / 核小体 / ARSACS / DNA 3'block / DNA break repair / single strand DNA break / AOAl / ataxia / aprataxin / サクシン欠損症 / nucleophosmin / 1本鎖DNA損傷 / アプラタキシン / 劣性遺伝性脊髄小脳変性症 … More Except Principal Investigator CAGリピート / DRPLA / 多系統萎縮症 / single sperm / AAA family protein / siRNA / Spastin / SCA6 / MJD / 神経変性 / 消化管神経叢 / グレリン / パーキンソン病 / シヌクレイノパチー / 機能画像 / hyperpolarization / magnetic resonance spectroscopy / 超高磁場 / 解剖学的解像度 / MR microscopy / 7テスラ / MRI / instability / マシャド・ジョセフ病 / ハンチントン病 / Hereditary spastic paraplegia / spastin / hereditary spastic paraplegia / Hereditary Spastic Paraplegia / AAAファミリー蛋白 / 遺伝性痙性対麻痺 / Huntington disease / Umbilical cord blood / Mitotic instability / Meiotic instability / CAG repeats / Laser microdissection / Huntington病 / 臍帯血 / mitotic instability / meiotic instability / レーザーマイクロダイセクション / germ line cells / laser capture microdissection / CAG repeat / sperm / germ line cell / gem line cell / レーザーキャプチャーマイクロダイセクション / 不安定性 / 病理学的解析 / 臨床研究 / 病理学的定量解析 / 臨床病理学的研究 / 神経病理学 / 認知機能障害 / 神経変性疾患 / 体格指数 / レプチン / 腸管神経 / 自律神経障害 / 消化器症状 / 自律神経 / 腸管ニューロン / 便秘 / 腸音解析 / 消化管機能 / 消化管神経 / アルファシヌクレイン / 超候磁場 / MR spectroscopy / tensor imaging / 3DAC / MJD1遺伝子 / Machado-Joseph病 / GTPシクロビロラーゼI / 瀬川病 / 福山型先天性ジストロフィー / SCA2 / 蛋白リン酸化 / 脊髄小脳変性症 / 神経栄養因子 / ジョセフ病 / 福山型先天性筋ジストロフィー / 脳移植 / 神経成長因子 / コリン作動性ニュ-ロン / βアミロイド / アルツハイマ-病 / ダウン症 / トリソミ-16マウス Less

Autoreguation of TDP-43 in ALSPrincipal Investigator
- Principal Investigator
  
  Nishizawa Masatoyo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Neuropathological analysis of multiple system atrophy with cognitive impairment
- Principal Investigator
  
  Tada Mari
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
The spectrum of pathological involvement of enteric nervous system in synucleinopathy
- Principal Investigator
  
  OZAWA Tetsutaro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Molecular pathogenesis of ALS: approach from TDP-43 function.Principal Investigator
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Magnetic Resonance Molecular Microimaging
- Principal Investigator
  
  NAKADA Tsutomu
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neuroscience in general
- Research Institution
  Niigata University
Enteric neurodegeneration : an approach to neural system exposed to environments
- Principal Investigator
  
  OZAWA Tetsutaro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
劣性遺伝性脊髄小脳変性症の分子病態の解明Principal Investigator
- Principal Investigator
  
  西澤正豊
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
劣性遺伝性脊髄小脳変性症の分子病態の解明Principal Investigator
- Principal Investigator
  
  西澤正豊
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
劣性遺伝性脊髄小脳変性症の分子病態の解明Principal Investigator
- Principal Investigator
  
  西澤正豊
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
High-resolution Clinical lmaging on 7.0 T MR system
- Principal Investigator
  
  NAKADA Tsutomu
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Neuroscience in general
- Research Institution
  Niigata University
Molecular mechanism of autosomal dominant hererditary spastic paraplegia type 4(SPG4)
- Principal Investigator
  
  TAKIYAMA Yoshihisa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical School
レーザーマイクロダイセクションを用いたCAGリピートの不安定化機構の研究
- Principal Investigator
  
  TAKIYAMA Yoshihisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical School
Relationship between intracellular traffic of proteins containing expanded polyglutamine, aggregate formation, and cell deathPrincipal Investigator
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  International University of Health and Welfare
  Jichi Medical University
The instability of expanded CAG repeats in the genes for CAG repeat Diseases
- Principal Investigator
  
  TAKIYAMA Yoshihisa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical School
遺伝性神経疾患の病的遺伝子の解明
- Principal Investigator
  
  金澤一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Machado-Joseph病原因遺伝子(MJD1)の不安定性について
- Principal Investigator
  
  TAKIYAMA Yoshihisa
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical University
神経細胞死とその修復の分子生物学
- Principal Investigator
  
  金澤一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Analysis of the qene for Machado-Joseph diseasePrincipal Investigator
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical School
Establishment of cerebellar Purkinje cell lines by somatic cell fusionPrincipal Investigator
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical School
トリソミ-16マウスを用いたアルツハイマ-病発症機序の解析
- Principal Investigator
  
  TABIRA Takeshi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Center of Neurology and Psychiatry
Analysis of pathogenetic mechanism of Alzheimer's disease using trisomy 16 chimera micePrincipal Investigator
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry (NCNP)

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 小脳と運動失調、小脳はなにをしているのか2013
- Author(s)
  西澤正豊、五十嵐　博中(分担)
- Total Pages
  336
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-21220007
[Book] 内科(第105巻第6号)、内科疾患の診断基準・病型分類・重症度、IX神経・筋、多系統萎縮症2010
- Author(s)
  小澤鉄太郎、高堂裕平、西澤正豊
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] Expression of aquaporin 1 and aquaporin 4 in the temporal neocortex of patients with Parkinson's disease.2016
- Author(s)
  Hoshi A, Tsunoda A, Tada M, Nishizawa M, Ugawa Y, Kakita A.
- Journal Title
  
  Brain Pathol.
  
  Volume: - Issue: 2 Pages: 160-168
- DOI
  10.1111/bpa.12369
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430048, KAKENHI-ORGANIZER-15H05871, KAKENHI-PROJECT-26461314, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] Pathological and Clinical Spectrum of Progressive Supranuclear Palsy: With Special Reference to Astrocytic Tau Pathology.2016
- Author(s)
  Yokoyama Y, Toyoshima Y, Shiga A, Tada M, Kitamura H, Hasegawa K, Onodera O, Ikeuchi T, Someya T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Brain Pathol.
  
  Volume: 26 Issue: 2 Pages: 155-166
- DOI
  10.1111/bpa.12265
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-15K09860
[Journal Article] Esophageal Involvement in Multiple System Atrophy.2015
- Author(s)
  Taniguchi H, Nakayama H, Hori K, Nishizawa M, Inoue M, Shimohata T.
- Journal Title
  
  Dysphagia
  
  Volume: 03 Issue: 6 Pages: 669-673
- DOI
  10.1007/s00455-015-9641-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25862078
[Journal Article] Apparent diffusion coefficients distinguish amyotrophic lateral sclerosis from cervical spondylotic myelopathy.2015
- Author(s)
  Koike Y, Kanazawa M, Terajima K, Watanabe K, Ohashi M, Endo N, Shimohata T, Nishizawa M.
- Journal Title
  
  Clin Neurol Neurosurg.
  
  Volume: 132 Pages: 33-6
- DOI
  10.1016/j.clineuro.2015.02.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25462817
[Journal Article] Effect of sodium pyruvate on exercise intolerance and muscle weakness due to mitochondrial myopathy: a case report2015
- Author(s)
  黒羽　泰子, 他田　真理, 河内　泉, 西澤　正豊, 松原　奈絵, 小池　亮子
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 55 Issue: 6 Pages: 412-416
- DOI
  10.5692/clinicalneurol.cn-000652
- NAID
  130005083894
- ISSN
  0009-918X, 1882-0654
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia.2015
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Tanaka H, Shimizu H, Shiga A, Miura T, Aoki K, Aikawa A, Ishizawa S, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Brain Pathology
  
  Volume: in press Issue: 1 Pages: 82-94
- DOI
  10.1111/bpa.12262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830038, KAKENHI-PROJECT-26250017, KAKENHI-PUBLICLY-26117506, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-15H04839
[Journal Article] Hereditary diffuse leukoencephalopathy with spheroids (HDLS): a review of the literature on its clinical characteristics and mutations in the colony-stimulating factor-1 receptor gene.2014
- Author(s)
  Konno T, Tada M, Tada M, Nishizawa M, Ikeuchi T.
- Journal Title
  
  Brain Nerve
  
  Volume: 66 Pages: 581-90
- NAID
  40020089061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] The circulating level of leptin and blood pressure in patients with multiple system atrophy.2014
- Author(s)
  Ozawa T, Tokunaga J, Arakawa M, Ishikawa A, Takeuchi R, Yokoseki A, Sone H, Nishizawa M.
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 347 Issue: 1-2 Pages: 349-51
- DOI
  10.1016/j.jns.2014.09.045
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591290, KAKENHI-PROJECT-24790875
[Journal Article] Haploinsufficiency of CSF-1R and clinicopathological characterization in patients with HDLS.2014
- Author(s)
  Konno T, Tada M, Tada M, Koyama A, Nozaki H, Harigaya Y, Nishimiya J, Matsunaga A, Yoshikura N, Ishihara K, Arakawa M, Isami A, Okazaki K, Yokoo H, Ihoh K, Yoneda M, Kawamura M, Inuzuka T, Takahashi H, Nishizawa M, Onodera O, Kakita A, Ikeuchi T
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 2 Pages: 139-148
- DOI
  10.1212/wnl.0000000000000046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PUBLICLY-24111517, KAKENHI-PROJECT-25293200, KAKENHI-PROJECT-25430048
[Journal Article] Safety of unsedated PEG placement using transoral ultrathin endoscopy in patients with amyotrophic lateral sclerosis.2014
- Author(s)
  Sato Y, Goshi S, Kawauchi Y, Nishigaki Y, Mizuno KI, Hashimoto S, Takeuchi M, Kobayashi M, Ozawa T, Nishizawa M, Aoyagi Y.
- Journal Title
  
  Nutritional Neuroscience.
  
  Volume: - Issue: 1 Pages: 71-75
- DOI
  10.1179/1476830514y.0000000161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591290
[Journal Article] Minor splicing pathway is not minor any more: implications for the pathogenesis of motor neuron diseases.2014
- Author(s)
  Onodera O, Ishihara T, Shiga A, Ariizumi Y, Yokoseki A, Nishizawa M.
- Journal Title
  
  Neuropathology
  
  Volume: 34 Issue: 1 Pages: 99-107
- DOI
  10.1111/neup.12070
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065
[Journal Article] [Aberration of the spliceosome in amyotrophic lateral sclerosis].2014
- Author(s)
  Ishihara T, Kakita A, Takahashi H, Onodera O, Nishizawa M.
- Journal Title
  
  Rinsho Shinkeigaku.
  
  Volume: 54 Pages: 1155-1157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253065
[Journal Article] Pathology and sensitivity of current clinical criteria in corticobasal syndrome.2014
- Author(s)
  Ouchi H, Toyoshima Y, Tada M, Oyake M, Aida I, Tomita I, Satoh A, Tsujihata M, Takahashi H, Nishizawa M, Shimohata T.
- Journal Title
  
  Mov Disord
  
  Volume: 29 Issue: 2 Pages: 238-44
- DOI
  10.1002/mds.25746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS2014
- Author(s)
  Konno T　ほか
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 40 Issue: 6 Pages: 783-788
- DOI
  10.1111/nan.12157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-25670417, KAKENHI-PLANNED-26117005, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017
[Journal Article] 多系統萎縮症の声帯外転障害と吸気性喘鳴：これまでの知見と問題点2014
- Author(s)
  小澤鉄太郎、関谷可奈子、西澤正豊
- Journal Title
  
  自律神経
  
  Volume: 51 Pages: 10-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591290
[Journal Article] Early clinical features of patients with progressive supranuclear palsy with predominant cerebellar ataxia.2013
- Author(s)
  Kanazawa M, Tada M, Onodera O, Takahashi H, Nishizawa M, Shimohata T.
- Journal Title
  
  Parkinsonism Relat Disord
  
  Volume: 19 Issue: 12 Pages: 1149-51
- DOI
  10.1016/j.parkreldis.2013.07.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] ERBB4 Mutations that Disrupt the Neuregulin-ErbB4 Pathway Cause Amyotrophic Lateral Sclerosis Type 19.2013
- Author(s)
  Takahashi Y, Fukuda Y, Yoshimura J, Toyoda A, (33名省略）, Morishita S, Goto J and Tsuji S.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 93 Issue: 5 Pages: 900-905
- DOI
  10.1016/j.ajhg.2013.09.008
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22129001, KAKENHI-PLANNED-22129002, KAKENHI-PLANNED-22129003, KAKENHI-PLANNED-22129008, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25860700, KAKENHI-PROJECT-221S0002
[Journal Article] Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.2013
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A, et al ;
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Issue: 20 Pages: 4136-4147
- DOI
  10.1093/hmg/ddt262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065
[Journal Article] Japanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF72.2013
- Author(s)
  Konno T
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 84(4) Issue: 4 Pages: 398-401
- DOI
  10.1136/jnnp-2012-302272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23591269, KAKENHI-PROJECT-24790875, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25670417
[Journal Article] Sporadic ALS with compound heterozygous mutation in the SQSTM1 gene.2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 126 Issue: 3 Pages: 453-459
- DOI
  10.1007/s00401-013-1150-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23590390, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25830038
[Journal Article] Japanese amyotrophiclateral sclerosis patients withGGGGCC hexanucleotide repeatexpansion in C9ORF722013
- Author(s)
  Konno T, Shiga A, Tsujino A, Sugai A,Kato T, Kanai K, Yokoseki A, Eguchi H,Kuwabara S, Nishizawa M, Takahashi H,Onodera O
- Journal Title
  
  J NeurolNeurosurg Psychiatry
  
  Volume: 84(4) Pages: 398-401
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Abnormal ghrelin secretion contributes to gastrointestinal symptoms in multiple system atrophy patients.2013
- Author(s)
  Ozawa T, Tokunaga J, Arakawa M, Ishikawa A, Takeuchi R, Mezaki N, Miura T, Sakai N, Hokari M, Takeshima A, Utsumi K, Kondo T, Yokoseki A, Nishizawa M
- Journal Title
  
  Journal of Neurology
  
  Volume: 260 Issue: 8 Pages: 2073-2077
- DOI
  10.1007/s00415-013-6944-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591290, KAKENHI-PROJECT-24790875
[Journal Article] Progressive myoclonus epilepsy: extraneuronal brown pigment deposition and system neurodegeneration in the brains of Japanese patients with novel SCARB2 mutations.2013
- Author(s)
  Fu YJ, Aida I, Tada M, Tada M, Toyoshima Y, Takeda S, Nakajima T, Naito H, Nishizawa M, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: epub ahead of print Issue: 5 Pages: 551-563
- DOI
  10.1111/nan.12057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] Transportin 1accumulates in FUS inclusions inadult-onset ALS without FUS mutation2013
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, ShigaA, Tanaka H, Shimohata M, Kimura K,Morita T, Kakita A, Nishizawa M,Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: Epub Issue: 5 Pages: 580-584
- DOI
  10.1111/nan.12022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23590390
[Journal Article] Spontaneous middle cerebral artery dissection demonstrated by high-resolution T1-weighted 3D image2013
- Author(s)
  Uemura M, Akaiwa Y, Toriyabe M, Mashima T, Terajima K, Shimohata T, Igarashi H, Nakada T, Nishizawa M
- Journal Title
  
  Cerebrovasc Dis
  
  Volume: 36 Issue: 3 Pages: 243-244
- DOI
  10.1159/000353873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220007, KAKENHI-PROJECT-25461310
[Journal Article] Alteration of P0LDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS2012
- Author(s)
  Shiga A, et al ;
- Journal Title
  
  PLoS ONE
  
  Volume: 7(8) Issue: 8 Pages: e43120-e43120
- DOI
  10.1371/journal.pone.0043120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23890060, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-24790875, KAKENHI-PLANNED-22129004
[Journal Article] 多系統萎縮症における内分泌異常、多系統萎縮症の内分泌異常:自律神経障害との関連2012
- Author(s)
  小澤鉄太郎、高堂裕平、西澤正豊
- Journal Title
  
  Clinical Neuroscience 2012
  
  Volume: 29 Pages: 228-231
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] Difference in MSA phenotype distribution between populations : genetics or environment?2012
- Author(s)
  Ozawa T, Revesz T, Paviour D, Lees AJ, Quinn N, Tada M, Kakita A, Onodera O, Wakabayashi K, Takahashi H, Nishizawa M, Holton JL
- Journal Title
  
  Journal of Parkinson's Disease
  
  Volume: 2 Pages: 7-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] Coexistence ofHuntington's disease and amyotrophiclateral sclerosis: aclinicopathologic study2012
- Author(s)
  Tada M, Coon EA, Osmand AP, Kirby PA,Martin W, Wieler M, Shiga A, ShirasakiH, Tada M, Makifuchi T, Yamada M,Kakita A, Nishizawa M, Takahashi H,Paulson HL
- Journal Title
  
  ActaNeuropathol
  
  Volume: 124(5) Pages: 749-60
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Reduction rateof body mass index predicts prognosisfor survival in amyotrophic lateralsclerosis: a multicenter study inJapan2012
- Author(s)
  Shimizu T, Nagaoka U, Nakayama Y,Kawata A, Kugimoto C, Kuroiwa Y, KawaiM,Shimohata T, Nishizawa M, Mihara B,Arahata H, Fujii N, Namba R, Ito H,Imai T,Nobukuni K, Kondo K, Ogino M,Nakajima T, Komori T
- Journal Title
  
  Amyotroph Lateral Scler
  
  Volume: 13(4) Pages: 363-6
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] パーキンソン病と多系統萎縮症の消化器症状：グレリンはどう関与するか？2012
- Author(s)
  小澤鉄太郎、徳永純、西澤正豊
- Journal Title
  
  自律神経
  
  Volume: 49 Pages: 221-226
- NAID
  10031145283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591290
[Journal Article] Cognitive impairment and cortical degeneration in neuromyelitis optica.2012
- Author(s)
  Saji E, Arakawa M, Yanagawa K, Toyoshima Y, Yokoseki A, Okamoto K, Otsuki M, Akazawa K, Kakita A, Takahashi H, Nishizawa M, Kawachi I.
- Journal Title
  
  Ann Neurol.
  
  Volume: 73 Issue: 1 Pages: 65-76
- DOI
  10.1002/ana.23721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220007, KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-23591236, KAKENHI-PROJECT-25350516
[Journal Article] 急性脳虚血によるTDP-43の生化学的・組織学的変化の検討2011
- Author(s)
  下畑享良, 金澤雅人, 柿田明美, 五十嵐博中, 高橋哲哉, 川村邦雄, 高橋均, 中田力, 西澤正豊
- Journal Title
  
  脳循環代謝
  
  Volume: 22巻2号 Pages: 40-45
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Inhibition of VEGF signaling pathway attenuates hemorrhage after tPA treatment2011
- Author(s)
  Kanazawa M, Igarashi H, Kawamura K, Teikahashi T, Kakita A, Takahashi H, Nakada T, Nishizawa M, Shimohata T
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 31 Pages: 1461-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220007
[Journal Article] Primary lateral sclerosis : Upper-motor-predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration-immunohistochemical and biochemical analyses of TDP-432011
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Ishidaira H, Tan CF, Tani T, Koike R, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology. 2011
  
  Volume: 32 Issue: 4 Pages: 373-384
- DOI
  10.1111/j.1440-1789.2011.01271.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113506, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-22659169, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23659184
[Journal Article] Reduced bowel sounds in Parkinson's disease and multiple system atrophy patients2011
- Author(s)
  Ozawa T, Saji E, Yajima R, Onodera O, Nishizawa M
- Journal Title
  
  Clin Auton Res
  
  Volume: 21(3) Pages: 181-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] A serial MRI study in a patient with progressive supranuclear palsy with cerebellar ataxia2011
- Author(s)
  Kanazawa M, Shimohata T, Endo K, Koike R, Takahashi H, Nishizawa M
- Journal Title
  
  Parkinsonism Relat Disord
  
  Volume: 18 Issue: 5 Pages: 677-679
- DOI
  10.1016/j.parkreldis.2011.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220007
[Journal Article] Brainstem metabolites in multiple system atrophy of cerebellar type : 3.0-T magnetic resonance spectroscopy study2011
- Author(s)
  Takado Y, Igarashi H, Terajima K, Shimohata T, Ozawa T, Okamoto K, Nishizawa M, Nakada T
- Journal Title
  
  Mov Disord
  
  Volume: 26 Pages: 1297-1302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220007
[Journal Article] 家族性ALSALS10(遺伝性ALS-TDP)の臨床と病理2011
- Author(s)
  今野卓哉, 石原智彦, 西澤正豊, 小野寺理
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 29巻9号 Pages: 1019-1021
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Biochemical and histopathological alterations in TAR DNA-binding protein-43 after acute ischemic stroke in rats2011
- Author(s)
  Kanazawa M, Kakita A, Igarashi H, Takahashi T, Kawamura K, Takahashi H, Nakada T, Nishizawa M, Shimohata T.
- Journal Title
  
  J Neurochem
  
  Volume: 116(6) Issue: 6 Pages: 957-65
- DOI
  10.1111/j.1471-4159.2010.06860.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 多系統萎縮症の自律神経病理:生命維持に関わる領域2011
- Author(s)
  小澤鉄太郎、他田真理、西澤正豊
- Journal Title
  
  Clinical Neuroscience 2011
  
  Volume: 29 Pages: 974-975
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] FTLD/ALS as TDP-43proteinopathies2010
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A,Yokoseki A, Sato T, Toyoshima Y,Kakita A,Takahashi H, Nishizawa M,Onodera O
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 50(11) Pages: 1022-4
- NAID
  130004504601
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] ALS Update ALSの病態 FUSの観点から2010
- Author(s)
  志賀篤, 西澤正豊, 小野寺理
- Journal Title
  
  医学のあゆみ
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 開眼失行を呈した筋萎縮性側索硬化症1前頭側頭葉変性症の1例2010
- Author(s)
  矢島隆二, 春日健作, 佐藤朋江, 池内健, 西澤正豊
- Journal Title
  
  臨床神経学
  
  Volume: 50 Pages: 645-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Tremulous arytenoid movements predict severity of glottic stenosis in multiple system atrophy2010
- Author(s)
  Ozawa T, Shinoda H, Tomita M, Shimohata T, Nakayama H, Nishizawa M
- Journal Title
  
  Mov Disord
  
  Volume: 25(10) Pages: 1418-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] Clinical and pathological spectrumof TDP-43 associated ALS2010
- Author(s)
  Onodera O, Yokoseki A, Tan CF,Ishihara T, Nishiira Y, Toyoshima Y,Kakita A, Nishizawa M, Takahashi H
- Journal Title
  
  RinshoShinkeigaku
  
  Volume: 50(11) Pages: 940-2
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 【神経変性疾患におけるTDP・43】家族性筋萎縮性側索硬化症とTDP-432010
- Author(s)
  石原智彦, 横関明男, 西澤正豊, 高橋均, 小野寺理
- Journal Title
  
  最新医学
  
  Volume: 65 Pages: 1648-1653
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] A case of amyotrophiclateral sclerosis/frontotemporallobar degeneration with apraxia ofeyelid opening2010
- Author(s)
  Yajima R, Kasuga K, Sato T, Ikeuchi T,Nishizawa M
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 50(9) Pages: 645-50
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Tract by tract morphometric and diffusivity analyses in vivo of spinocerebellar degeneration2009
- Author(s)
  Terajima K. Matsuzawa H, Shimohata T. Nishizawa M. Nakada T.
- Journal Title
  
  Journal of Neuroimaging (In Press)
- Data Source
  KAKENHI-PROJECT-16100003
[Journal Article] TDP-43 mutation in familial amyotrophic lateral sclerosis2008
- Author(s)
  Yokoseki A, Shiga A, Tan C -F, Tagawa A, Kaneko H, Koyama A, Eguchi H, Tsujino A, Ikeuchi T, Kakita A, Okamoto K, Nishizawa M, Takahashi H, Onodera O
- Journal Title
  
  Ann Neurol 63
  
  Pages: 538-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Sporadic amyotrophic lateral sclerosis : two pathological patterns shown by analysis of distribution of TDP-43-immunoreacti ve neuronal and glial cytoplasmic inclusions2008
- Author(s)
  Nishihira Y, Tan C-F, Onodera O, Toyoshima Y, Yamada M, Morita T, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Acta Neuropathol 116
  
  Pages: 169-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Patients homozygous and heterozygous for SNCA duplication in a family with parkinsonism and dementia2008
- Author(s)
  Ikeuchi T, Kakita A, Shiga A, Kasuga K, Kaneko H, Tan C-F, Idezuka J, Wakaba yashi K, Onodera O, Iwatsubo T, Nishizawa M, Takahashi H. Ishikawa A
- Journal Title
  
  Arch Neurol 65
  
  Pages: 514-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Cardiac sympathetic denervation in Parkinson's disease Iinked to SNCA duplication2008
- Author(s)
  Orimo S, Uchihara T, Nakamura A, Mori F, Ikeuchi T, Onodera O, Nishizawa M, Ishikawa A, Kakita A, Wakabayashi K, Takahashi H
- Journal Title
  
  Acta Neuropathol 116
  
  Pages: 575-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Mutational analysis in early-onset familial dementia in Japanese population : Role of PSENJ and MAPT R406W mutations2008
- Author(s)
  Ikeuchi T, Kaneko H, Miyashita A, Nozaki H, Kasuga K, Tsukie T, Imamura T, Ishizu H, Aoki K, Ishikawa A, Onodera O, Kuwano R, Nishizawa M
- Journal Title
  
  Dementia Geriatr Cogn Disord 26
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Serial Assessments of Delayed Encephalopathy after Carbon Monoxide Poisoning Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging on 3.0T System2008
- Author(s)
  Terajima K, Igarashi H, Hirose M, Matsuzawa H, Nishizawa M. Nakada T.
- Journal Title
  
  Eur Neurol 59(1)
  
  Pages: 55-61
- Data Source
  KAKENHI-PROJECT-16100003
[Journal Article] Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology2008
- Author(s)
  Nishihira Y, Tan C-F, Hoshi Y, Iwanaga K, Yamada M, Kawachi I, Tsujihata M, Hozumi I, Morita T, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Acta Neuropatho 117
  
  Pages: 45-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Development of a high- throughput microarray-based resequencing system for neurological disorders and its application to molecular genetics of amyotropic lateral sclerosis2008
- Author(s)
  Takahashi Y, Seki N,Ishiura H, Mitsui J, Matsukawa T, Kishino A, Onodera 0, Aoki M, Shimozawa N, Murayama S, Itoyama Y, Suzuki Y, Sobue G, Nishizawa M, Goto J. Tsuii S
- Journal Title
  
  Arch Neurol 65
  
  Pages: 1326-1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Frequency of nocturnal sudden death in patients with multiple system atrophy2008
- Author(s)
  Shimohata T, Ozawa T, Nakayama H, Tomita M, Shinoda H, Nishizawa M
- Journal Title
  
  J Neurol 255
  
  Pages: 1483-1485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families2008
- Author(s)
  Hara K, Shiga A, Nozaki H, Mitsui J, Takahashi Y, Ishiguro H, Yomono H, Kurisaki H, Goto J, Ikeuchi T, Tsuji S, Nishizawa M, Onodera O
- Journal Title
  
  Neurology 71
  
  Pages: 547-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023012
[Journal Article] Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with 3'-phosphate and 3'-phosphoglycolate ends.2007
- Author(s)
  Takahashi T, Tada M, Igarashi S, Koyama A, Date H, Yokoseki A, Shiga A, Yoshida Y, Tsuji S, Nishizawa M, Onodera O:
- Journal Title
  
  Nucl Acid Res 35
  
  Pages: 3797-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023015
[Journal Article] New mutation in the non-gigantic exon of SACS in Japanese siblings.2007
- Author(s)
  Takado Y, Hara K, Shimohata T, Tokiguchi S, Onodera O, Nishizawa M
- Journal Title
  
  Mov Disord 22
  
  Pages: 748-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023015
[Journal Article] Sacsin-related ataxia with neither retinal hypermyelination nor spasticity.2007
- Author(s)
  Hara K, Shimbo J, Nozaki H, Kikugawa K, Onodera O, Nishizawa M:
- Journal Title
  
  Mov Disord 22
  
  Pages: 1362-1363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023015
[Presentation] The SMN gene copy number states in Japanese ALS patients.2015
- Author(s)
  T.Ishihara, S.Toyoda, A.Koyama, R.Nakamura, G. Tohnai, N.Atsuta, G.Sobue, M.Nishizawa, O. Onodera
- Organizer
  10th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  Chicag (USA)
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Overexpression of intrinsic TDP-43 by disruption of the autoregulation in vivo.2015
- Author(s)
  Akihiro Sugai, Taisuke Kato, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  EMBO | EMBL Symposia Mechanisms of Neurodegeneration
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Depletion of TDP-43 induces mitochondrial fragmentation.2015
- Author(s)
  Ito G, Koyama A, Shiga A, Hirokawa S, Toyoshima Y, Kakita A, Nishizawa M, Onodera O.
- Organizer
  26th International Symposium on ALS/MND
- Place of Presentation
  Orland (USA)
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 多系統萎縮症におけるレプチン分泌と体格指数ならびに起立性低血圧との関連の検討2014
- Author(s)
  小澤鉄太郎、徳永純、石川厚、荒川武蔵、竹内亮子、横関明男、西澤正豊
- Organizer
  第５５回日本神経学会学術大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24591290
[Presentation] Serum leptin level, body mass index, and blood pressure in patients with multiple system atrophy2014
- Author(s)
  Tetsutaro Ozawa, Jun Tokunaga, Musashi Arakawa, Atsushi Ishikawa, Ryoko Takeuchi, Akio Yokoseki and Masatoyo Nishizawa
- Organizer
  18th International Congress of Parkinson’s Disease and Movement Disorders
- Place of Presentation
  スエーデン、ストックホルム
- Data Source
  KAKENHI-PROJECT-24591290
[Presentation] TDP-43量はTDP-43に惹起される自己mRNAのスプライシングで制御される2013
- Author(s)
  須貝章弘、小山哲秀、今野卓哉、加藤泰介、西澤正豊、小野寺理
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的解析2013
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５４回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] TDP-43 is autoregulated by multiple excisions of introns in exon6 and reservation of mRNA in nucleus by TDP-432013
- Author(s)
  Akihide Koyama, Akihiro Sugai, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  24th International Symposium on ALS/MND
- Place of Presentation
  Milan　イタリア
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Alternative splicing or polyadenylation, which is the major mechanism for auto-regulation of TDP-43?2013
- Author(s)
  Akihiro Sugai, Akihide Koyama, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  RNA Metabolism in Neurological Disease:8th Brain Research Conference
- Place of Presentation
  SanDiego アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 多系統萎縮症の消化器症状にはグレリンが関与する。2013
- Author(s)
  小澤鉄太郎、徳永純、石川厚、荒川武蔵、竹内亮子、横関明夫、西澤正豊
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591290
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的解析2013
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５４回日本神経病理学会総会学術研究会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] シヌクレイノパチーにおけるグレリン分泌異常は消化器症状に関与するか？2012
- Author(s)
  小澤鉄太郎，徳永純，荒川武蔵，石川厚*、竹内亮子，横関明男，西澤正豊
- Organizer
  第65回日本自律神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591290
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討Splicing factors involved in an autoregulation of the ALS-associated protein TDP-432011
- Author(s)
  桑原美咲, 石原智彦, 志賀篤, 今野卓哉, 小山哲秀, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs in amyotrqohic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing ofPOLDIP3 gene in motor neuron with ALS.2011
- Author(s)
  A. SHIGA1, T. ISHIHARA1, A.MIYASHITA1, T. KATO1, M. KUWABARA1, A. YOKOSEKI2, R. KUWANO1, A. KAKITA1,H. TAKAHASHI1, M. NISHIZAWA1, O. ONODERA1
- Organizer
  6th Brain Research Conference RNA-Binding Proteins in NeurologicalDisease
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs inamyotrophic lateral sclerosis2011
- Author(s)
  T. ISHIHARA, A. SHIGA, A. KAKITA A.YOKOSEKI, M. NISHIZAWA, H. TAKAHASHI,O. ONODERA
- Organizer
  6th Brain Research Conference RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討Splicing factors involved in anautoregulation of the ALS-associated protein TDP-432011
- Author(s)
  桑原美咲,石原智彦,志賀篤,今野卓哉,小山哲秀,西澤正豊,小野寺理
- Organizer
  分子生物学
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tardbp alternatively spliced mRNA andtissue-specific variation inheterozygous Tardbp-deficient mice2011
- Author(s)
  廣川祥子,佐藤俊哉,石原知彦,藤野赳至,近藤千草,横山峯介,崎村健司,西澤正豊,小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A. MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERAI
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tar dbp alternatively spliced mRNA and tissue-specific variation in heterozy gous Tardbp-deficient mice2011
- Author(s)
  廣川祥子, 佐藤俊哉, 石原知彦, 藤野赳至, 近藤千草, 横山峯介, 崎村健司, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs inamyotrophic lateral sclerosis2011
- Author(s)
  T. ISHIHARA, A. SHIGA, A. KAKITA A.YOKOSEKI, M. NISHIZAWA, H. TAKAHASHI, O. ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing ofPOLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A. SHIGA1, T. ISHIHARA1, A.MIYASHITA1, T. KATO1, M. KUWABARA1, A. YOKOSEKI2, R. KUWANO1, A. KAKITA1,H. TAKAHASHI1, M. NISHIZAWA1, O.ONODERA1
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Cytoplasmic C-Terminus TDP-43 Aggregate Leads to Increased Phosphorylation of Full-Length TDP-43 in Culture Cell2010
- Author(s)
  Ariizumi, Y Ishihara, T.Yokoo, M.Shiga, A.Yokoseki, A.Onodera, O.Nishizawa, M
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] TDP-43 depletion causes splicing defects in the genes associated with endomemb rane system.2010
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, M.YOKOO, Y..ARIIZUMI, A.YOKOSEKI, R.KUWANO, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] TDP-43 depletion causes splicingdefects in the genes associated withendomembrane system2010
- Author(s)
  A. SHIGA, T. ISHIHARA, A. MIYASHITA,M. YOKOO, Y. ARIIZUMI, A. YOKOSEKI,R. KUWANO, M. NISHIZAWA, O. ONODERA
- Organizer
  Neuroscience 2010 Saturday
- Place of Presentation
  SanDiego
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs inAmyotrophic Lateral Sclerosis2010
- Author(s)
  Ishihara, T. Shiga, A. Kakita A.Yokoseki A. Nishizawa M. Takahashi, H.Onodera O
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Cytoplasmic C-Terminus TDP-43 Aggregate Leads to Increased Phosphorylation of Full-LengthTDP-43 in Culture Cell2010
- Author(s)
  Ariizumi, Y. Ishihara, T. Yokoo, M.Shiga, A. Yokoseki A. Onodera O.Nishizawa M
- Organizer
  AAN
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs in Amyotrophic Lateral Sclerosis2010
- Author(s)
  Ishihara, T.Shiga, A.Kakita, A.Yokoseki, A.Nishizawa, M.Takahashi, H.Onodera, O
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Molecular mechanism of nucleolar localization of aprataxin, causative protein for a neurodegenerative disorder2008
- Author(s)
  Sato T, Koyama A, Tada M, Shiga A, Igarashi S, Nishizawa M, Onodera O
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington, DC.USA
- Data Source
  KAKENHI-PROJECT-20023012
[Presentation] Aprataxin, the causative gene product for AOA1/EAOH, repairs damaged 3-ends of DNA single strand breaks.2007
- Author(s)
  Tads, M., Koyama, A., Igarashi, S., Yokoseki, A., Takahashi, T., Shiga, A., Tsuji, S., Nishizawa. M. & Onodera, O.
- Organizer
  59th Annual meeting of the American Academy of Neurology
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-18023015
[Presentation] Aberration of the spliceosome in amyotrophic lateral sclerosis
- Author(s)
  石原智彦，柿田明美，高橋均，小野寺理，西澤正豊
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Invited
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Coordinated autoregulation of TDP-43 and its implication for TDP-43 pathology
- Author(s)
  須貝章弘　小山哲秀　加藤泰介　志賀篤　今野卓哉　小山美咲　石原智彦　西澤正豊　小野寺理
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Invited
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的異常
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，山本　徹，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５５回日本神経病理学会総会学術研究会
- Place of Presentation
  東京都千代田区一ツ橋　学術総合センター
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] Hereditary diffuse leukoencephalopathy with spheroids (HDLS): Histological features of microglia
- Author(s)
  Mari Tada, Takuya Konno，Masayoshi Tada，Ken-ichi Okazaki，Musashi Arakawa，Kyoko Itoh，Toru Yamamoto, Hideaki Yokoo, Nobuaki Yoshikura，Kenji Ishihara, Yasuko Toyoshima, Osamu Onodera, Masatoyo Nishizawa, Takeshi Ikeuchi，Hitoshi Takahashi，Akiyoshi Kakita
- Organizer
  American Academy of Neurology Annual meeting 2014
- Place of Presentation
  Pennsylvania Convention Center in Philadelphia, PA, USA
- Year and Date
  2014-04-26 – 2014-05-03
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的異常
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，山本　徹，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５５回日本神経学会学術総会
- Place of Presentation
  福岡国際会議場・福岡サンパレス・福岡国際センター
- Year and Date
  2014-05-21 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] The reduction of minor spliceosome and aberrant splicing in ALS.
- Author(s)
  T. Ishihara., A. Koyama M., Nishizawa. O. Onodera.
- Organizer
  Cell Symposium
- Place of Presentation
  Berkeley, CA, USA
- Year and Date
  2014-10-19 – 2014-10-21
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Endogenous TDP-43 over-expression model with disrupted auto-regulation
- Author(s)
  Akihiro Sugai, Taisuke Kato, Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  10th Annual Meeting of the Oligonucleotide Therapeutics Society.
- Place of Presentation
  Hilton San Diego Resort & Spa, San Diego, California
- Year and Date
  2014-10-12 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Update in amyotrophic lateral sclerosis
- Author(s)
  Osamu Onodera, Masatoyo Nishizawa, Hitoshi Takahashi
- Organizer
  The XVIII International Congress of Neuropathology. ICN 2014
- Place of Presentation
  Rio de Janeiro, Brazil
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25253065

1. TAKIYAMA Yoshihisa (00245052)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. KAKITA Akiyoshi (80281012)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
3. SATOU Toshiya (90359703)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. TABIRA Takeshi (80112332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAHASHI Keikichi (40117148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KUNISHITA Tatsuhide (40167383)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NAKADA Tsutomu (50281720)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. FUJII Yukihiko (40283014)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SUZUKI Kiyotaka (40303169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. OZAWA Tetsutaro (10377153)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
11. TAKAHASHI Hitoshi (90206839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
12. ONODERA Osamu (20303167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 40 results
13. 金澤一郎 (30110498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 黒澤良和 (10109259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 近藤郁子 (20110489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 辻省次 (70150612)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. 原賢寿 (10377195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
18. IGARASHI Hironaka (20231128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. HUBER Vincent (40422620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TSUJITA Mika (60397180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ABE Manabu (10334674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KUWANO Ryozo (20111734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
23. ISHIHARA Tomohiko (70612232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
24. Tada Mari (30646394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
25. SHIMOHATA Takayoshi (60361911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. TOMINAGA S (70155571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ARAKI M (00118449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OGAWA M (50194452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. NIIJIMA K (80150613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KAWASHIMA Shingo (30254915)

# of Collaborated Projects: 1 results

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31. SHIMAZAKI Haruo (30316517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. HANAOKA Kazunori (40189577)

# of Collaborated Projects: 1 results

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33. 榊佳之 (10112327)

# of Collaborated Projects: 1 results

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34. 高坂新一 (50112686)

# of Collaborated Projects: 1 results

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35. 古川昭栄 (90159129)

# of Collaborated Projects: 1 results

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36. 黒田洋一郎 (30073084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 高橋昭 (30022784)

# of Collaborated Projects: 1 results

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38. 池田穣衛 (50266467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 横関明男 (90515719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
40. NAMEKAWA Michito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. KAMEGAI Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. KWEE Ingrid L.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. KNIGHT Robert T.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. MORISHITA Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. TOYOSHIMA Yasuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 豊田敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 清水宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishizawa Masatoyo 西澤 正豊

NISHIZAWA Masatoyo 西澤 正豊

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Autoreguation of TDP-43 in ALSPrincipal Investigator

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Molecular pathogenesis of ALS: approach from TDP-43 function.Principal Investigator

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劣性遺伝性脊髄小脳変性症の分子病態の解明Principal Investigator

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劣性遺伝性脊髄小脳変性症の分子病態の解明Principal Investigator

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劣性遺伝性脊髄小脳変性症の分子病態の解明Principal Investigator

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Relationship between intracellular traffic of proteins containing expanded polyglutamine, aggregate formation, and cell deathPrincipal Investigator

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Nishizawa Masatoyo 西澤正豊

NISHIZAWA Masatoyo 西澤正豊