TAMAMURA Hirokazu 玉村啓和

… Alternative Names

玉村啓和タマムラヒロカズ

Less

Researcher Number	80217182
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, 生体材料工学研究所, 教授 2005 – 2022: Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineerings, Professor, 生体材料工学研究所, 教授 2004: Kyoto University, Grad School of Pharm.Sci., Associate Professor, 薬学研究科, 助教授 2001 – 2003: 京都大学, 薬学研究科, 講師 2002: 京都大学, 薬学研究科, 教授 … More 1997 – 1999: Kyoto University, Graduated School of Pharmaceutical Sciences, Assistant Profess, 薬学研究科, 講師 1997: 京都大学, 大学院・薬学研究科, 講師 1993 – 1996: 京都大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Biological Sciences / Chemical pharmacy / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / 医薬分子機能学 / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator 医薬分子機能学 / Chemical pharmacy … More / Drug development chemistry / Basic Section 54030:Infectious disease medicine-related / Basic Section 49060:Virology-related / Bioorganic chemistry / Virology / Functional basic dentistry Less
Keywords	Principal Investigator CXCR4 / T140 / HIV / 環状ペプチド / CXCR4アンタゴニスト / T22 / GPCR / 膜融合阻害剤 / βセクレターゼ阻害剤 / アンタゴニスト … More / ケモカインレセプター / 抗HIV活性 / タキプレシン / ペプチドミメティック / 二量体 / がん / FC131 / HIV侵入阻害剤 / 非ペプチド化 / コンビナトリアルケミストリー / ジメチルスルホキシド / ジスルフィド結合形成 / ケモカイン受容体CXCR4 / コンジュゲート / 中分子 / エイズ / 2価結合型リガンド / ケモカインレセプターCXCR4 / 分子プローブ / マトリックス蛋白 / インテグラーゼ阻害剤 / CD4ミミック / 慢性関節リウマチ / 癌転移 / 低分子化 / ジペプチドイソスター / アルツハイマー病 / SC34 / hydroxyethylamine / O, N-acyl転位反応 / ケモカイン / トリフルオロメタンスルホン酸銀 / 位置選択 / 薬物送達 / 中分子化合物 / コンジュゲート分子 / 上皮成長因子受容体 / 創薬リード / 上皮成長因子受容体EGFR / ハイブリッド分子 / PKC / kick & kill / 抗HIV剤 / 再活性化 / 潜伏感染細胞 / DAG-lactone / タンパク質リン酸化酵素 / 潜伏感染再活性作用 / conjugate化合物 / プロテアーゼ阻害剤 / 蛍光共鳴エネルギー移動 / ジアシルグリセロールーラクトン / kick and kill / HIV潜伏感染再活性化作用 / タンパク質リン酸化酵素C / ドラッグシャトル / 二量体構造認識プローブ / ポリプロリン / ポリプロリン鎖 / 二量体化 / Gタンパク質共役型受容体 / プローブ / 2価型リガンド / GPCR二量体 / 2価結合型GPCRリガンド / 高次構造模倣型 / 2価型 / 二次構造 / 中分子創薬 / 医薬品開発 / ヒト免疫不全ウイルス / ステープルペプチド / cyclic peptide / rheumatoid arthritis / leukemia / cancer metastasis / HIV infection / CXCR4 antagonist / chemokine receptor / 乳癌 / 膵臓癌 / 癌転移抑制剤 / 低分子 / ペプチドミミック / 部分ペプチドライブラリー / 耐性ウイルス / 抗エイズ薬 / フォワードケミカルゲノミクス / 薬剤耐性ウイルス / HIV感染症 / 治療標的 / ペプチドライブラリー / エンベロープタンパク質gp41 / カプシドタンパク質 / 多量体形成 / 抗HIV薬 / スイッチオン・オフ型 / 近赤外領域 / イメージング / がん細胞 / 認識ユニット / ２価結合型リガンド / 創薬ツール / 分子標的 / 関節リウマチ / 間節リウマチ / 関節リホマチ / アンタグニスト / 癌 / D環状ペプチド / 構造活性相関 / 低分子阻害剤 / リウマチ関節炎 / 環状ペンタペプチド / 抗HIV / protein kinase C / γ-lactone / ジアシルグリセロール / アミロイドβペプチド / PK-C活性化剤 / αセクレターゼ活性 / de novo設計 / T細胞指向性HIV-1 / アスパルチルプロテアーゼ / (E)-アルケン / 基質遷移状態模倣型 / X線結晶解析 / 人工設計 / 6 helical bundle構造 / ペプチドイソスター / aza-version Payne転位反応 / 基質遷移状態 / βアミロイド前駆体蛋白質 / (E)-アルケンジペプチドイソスター / コンホメーション固定化 / 生体内安定化 / docking analysis / HIVコレセプター / CXR4拮抗剤 / ケモカイン受容体 / 生体内安定性 / 構造活性相関研究 / T細胞指向性 / コレセプター / de novoデザイン / 薬剤耐性型抗HIV剤 / 6-helical bundle構造 / HIV外皮蛋白質gp41 / 立体選択的合成法 / aza-Payne転位反応 / hydroxyethylamine型イソスター / 侵入阻害 / タキプレッシン / AZT / conjugate / ターゲッティング / トリメチルシリルクロライド / 脱保護 / シスチン含有ペプチド / プロテグリン / エンドセリン / トリプトファン … More Except Principal Investigator HIV-1 / 環状ペプチド / 有機銅試薬 / HIV / ペプチド / 二量体化 / SARS-CoV / 膜融合 / α-helix / Constitutively Active Receptor Technology / 創薬研究 / CXCR4拮抗剤 / T140 / HIVプロテアーゼ阻害剤 / エイズ / 癌 / 立体配座固定 / ペプチドイソスター / リン酸化ペプチド / Bombesin Antagonist / 抗腫瘍活性 / ボンベシンアンタゴニスト / T22 / polyphemusin / tachyplesin / Avidin-biotin / カプシド蛋白質 / NMR / 抗HIV剤 / 侵入阻害剤 / I型膜融合 / 低分子 / 二量体 / 阻害ペプチド / 阻害剤 / 二量化アーム / 抗がん薬 / アラニン置換 / ＥＧＦレセプター / 共焦点レーザー顕微鏡 / 抗がん薬リード / 細胞内輸送 / フルオレセイン標識 / フルオレセイン / 細胞内薬物送達分子 / 抗がん活性ペプチド / 蛍光プローブ / 二量体化アーム / 二量化阻害 / EGFレセプター / peptide / anti-viral agents / membrane fusion / SARS / a-helix / 抗ウイルス剤 / G-protein coupled receptor / chemical ligation / CXCR4 antagonist / Peptide Chemistry / peptide-isosteres / drug discovery / genome science / ユニバーサル創薬テンプレート / αVβ3-integrin / 7TM-GPCR / CXCR4 / SARS Corona Virus / プロテオーム / ゲノム / リウマチ / Germinal Center / HIV感染 / 7回膜貫通型レセプター / 創薬テンプレート / 蛋白質化学 / ゲノム情報 / 7回膜貫通型GPCR / Chemical Ligation / ペプチド化学 / ゲノム科学 / samarium dienolate / one-electron reducing agent / samarium diiodide / dipeptide isosteres / fluoroalkene / organocopper reagents / ペプチドミメティック / ヨウ価サマリウム / ジペプチドイスター / Sm-ジエノラート / 一電子還元剤 / ヨウ化サマリウム / ジペプチドイソスター / フルオロアルケン / de novo design / HIV-cell fusion inhibitors / low molecular weight CXCR4 antagonists / T-cell line-tropic HIV / chemokine receptor / anti-HIV agents / 有用金属試薬 / コンビナトリアル合成 / エイス / 逆転写酵素阻害 / T140立体構造 / CXCR4ケモカイン受容体 / HIV第二受容体拮抗剤 / gp41 / 二価官能性抗HIV剤 / 多剤耐性克服型抗HIV剤 / HIV-cell融合阻害剤 / spring8 / SC34EK / gp41-標的型HIV-Cell膜融合阻害剤 / FC131 / T140-CXCR4ドッキング解析 / 機能性CXCR4変異体 / ホモロジーモデリング / 環状ペンタペプチドライブラリー / de novo設計 / T細胞指向性HIV-1 / HIV侵入阻害剤 / CXCR4アンタゴニスト / de novo分子設計 / 膜融合阻害剤 / 低分子化 / 多剤耐性HIV / T細胞指向性HIV / CXCR4ケモカインレセプター / HIV進入阻害剤 / 不斉補助基 / クロスカップリング反応 / ホスファターゼ / 非水解性リン酸化アミノ酸 / Alkene-type tipeptide isostere / Organocopper Reagent / HIV-protease / β-Secretase / aza-Payne Rearrangement / Substrate Transition State Mimic / Aspartyl Protease / Stereoselective Synthesis / ケモカインアンタゴニスト / 遷移金属触媒 / 基質遷移状態ミミック構造 / 非天然型アミノ酸誘導体 / (E)-Alkcnc型dipcptidcisostcrc / オレフィンメタセシス閉環反応 / 基質遷移状態模倣型酵素阻害剤 / aza-Payne転位反応 / Plasmepsin II / 多剤耐性HIV型プロテアーゼ / マラリア / β-secretase / グローバル配座固定 / Ru-触媒メタセシス閉環反応 / ペプチドリード医薬品 / 有機亜鉛-銅複合試薬 / アルツハイマー型痴呆症 / αVβ3インテグリン拮抗剤剤 / ゲノム情報集約型ライブラリー / アルケン型ジペプチドイソスター / HIVプロテアーゼ / β-セクレターゼ / aza-Payne転位 / 基質遷移状態模倣型阻害剤 / アスパルチルプロテアーゼ / 立体的選択的合成反応 / Allylpalladium Complex / Organopalladium Compound / Vinylaziridine / Aziridinylenoate / Alkene Isostere / SN2-type Ring-Opening / Organocopper Compound / トリプトフアン・イソスター / トリプトファン・イソスター / アリルパラジウム錯体 / 有機パラジウム化合物 / ビニルアジリジン / アジリジニル・エノエイト / アルケンイソスター / SN2型開環反応 / ボンベシン・アンタゴニスト / 有機銅化合物 / dimethylphosphono amino acids / final deprotection / peptide synthesis / phosphopeptides / phosphoamino acid / フラグメント結合 / ジメチルホスフェートアミノ酸 / 最終脱保護 / ペプチド合成 / リン酸化 / Stereocontrolled Synthetic Route / Anti-Cancer Activity / Inhibition of Amylase Release / (E)-Alkene Dipeptide Isosters / Palladium(0) / Activated Aziridinyl Enoates / Organocopper Reagents / 膵癌細胞増殖抑制 / 遷移金属触媒による異性化反応 / (E)-アルケン型ジペプチドイソスター / 立体特異的1,3-不斉転移 / キラルプール / 立体制御合成プロセス / アミラーゼ分泌抑制 / (E)-アルケンジペプチドイソスター / 0価パラジウム / 活性化アジリジンエノエ-ト / solution-phase synthesis / HCI / AgOTf-DMSO / T cell / beta-sheet / anti-HIV activity / β-sheet / DMSO / AgOTf / HCl / AgOTf‐DMSO / 液相合成 / T細胞 / β‐sheet / 抗HIV活性 / Affinity purification / Defensin / Protegrin / Self-defense peptide / Disulfide bond / Solid-phase synthesis / アフィニティークロマト / デフェンシン / プロテグリン / 生体防御ペプチド / ジスルフィド結合 / 固相合成 / Nonhydrolyzable Phosophopeptide / Tau-protein / Trk-receptor / Disulfide-bond Formation / Chemoselective Purification / Neurotrophin / Alzheimer Disase / Senile Dementia / Arg-vasopressin(4-9) / アフィニテイークロマト / Biotin化試薬 / 老人性痴呆症 / ジスルフィド形成 / ジメチルスルホキシド / 化学選択的固定化 / 二価官能性試薬 / フラグメント縮合 / NGF / アルツハイマー / NGF合成促進因子 / 非水解性リン酸化ペプチド / Tau蛋白質 / Trk受容体 / ジスルフィド形成反応 / 化学選択的精製法 / 神経栄養因子 / アルツハイマー型痴呆 / 老人性痴呆 / マトリックス蛋白質 / 抗HIV-1活性 / カプシド / 抗HIV-1薬 / Gag蛋白質 / 結晶構造解析 / RANKL / 構造生物学 / 骨形成促進 / 逆シグナル / ＲＡＮＫＬ / 歯科薬理学 Less

環状ペプチド誘導体を活用した標的選択的ハイブリッド型中分子医薬品の創製Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tokyo Medical and Dental University
カプシド蛋白質の二量体化を標的とした新規抗HIV薬開発に向けた基礎研究
- Principal Investigator
  
  村上努
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  National Institute of Infectious Diseases
Development of target-selective mid-size drugs using cyclic peptide derivativesPrincipal Investigator
- Principal Investigator
  
  Tamamura Hirokazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo Medical and Dental University
Development of new therapies targeting latent infection for a radical cure of HIV infectious diseases and AIDSPrincipal Investigator
- Principal Investigator
  
  Tamamura Hirokazu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
Development of highly active HIV fusion inhibitors
- Principal Investigator
  
  Murakami Tsutomu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  National Institute of Infectious Diseases
Chemical Biology Researches Using Recognition Units for GPCR DimersPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of mid-size drugs based on peptidomimeticPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Inhibition of HIV-1 by Gag peptides
- Principal Investigator
  
  Murakami Tsutomu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Development of anti-HIV agents targeting weak points of viral replication mechanismPrincipal Investigator
- Principal Investigator
  
  Tamamura Hirokazu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Studies on new chemical probes development that assumed dimeric interface of the EGF receptor ectodomain a target
- Principal Investigator
  
  Mizuguchi Takaaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of early diagnostic methods for cancer tissue and metastasis utilizing bivalent GPCR ligandsPrincipal Investigator
- Principal Investigator
  
  TAMAMURA HIROKAZU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of swich on-off type probes for detection of GPCR dimersPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of a new anabolic peptide on bone by the identification
- Principal Investigator
  
  AOKI Kazuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
Development of anti-HIV agents using chemical genomics based on viral self-regulation mechanismPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of anti-HIV agents targeting dynamic supramolecular mechanism and feedback mechanismPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hiraokazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
Medicinal chemistry based peptides against intractable disease including AIDS. Cancer and rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University
アミロイドβペプチドの蓄積を抑制するβセクレターゼ阻害剤の合成研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
CXCR4とgp41をダブルターゲットとした人工設計型HIV侵入阻害剤の創製研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
  Kyoto University
アミロイドβペプチドの蓄積を抑制するβセクレターゼ阻害剤の合成研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
CXCR4とgp41をダブルターゲットとした人工設計型HIV侵入阻害剤の創製研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of anti-HIV-1 peptides based on the concept of the discrimination of helical surfaces
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokushima
  Kyoto University
DEVELOPMENT OF CXCR4 ANTAGONISTS TARGETED TO ANTI-CANCER-METASTATIC AGENTS AND ANTI-HIV AGENTSPrincipal Investigator
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  KYOTO UNIVERSITY
アミロイドβペプチドの蓄積を抑制するβセクレターゼ阻害剤の合成研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
HIV外皮蛋白断片gp41-C34を基にした人工設計型細胞融合阻害剤の創製研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Genome/Proteome-lead Drug Discovery Based on Peptide/Protein Chemistry
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
アミロイドβペチプドの蓄積を抑制するβセクレターゼ阻割剤の合成研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
HIV外皮蛋白断片gp41-C34を基にした人工設計型細胞融合阻害剤の創製研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
低分子CXCR4アンタゴニストT140を基盤構造とした抗エイズ治療薬の開発研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Synthesis of Fluoroalkene Dipeptide Isosteres Using Organocopper Reagents
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
DEVELOPMENT OF NOVEL ANTI -HIV AGENTS BASED ON HIGHLY' SELECTIVE CHEMOKINE RECEPTOR CXCR$ ANTAGONISTS
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
低分子CXCR4アンタゴニストT22を基盤構造とした抗エイズ治療薬の開発研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Studies on Practical Strategy for Peptide-lead Drug Discovery and Development
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
Synthesis of secondary difluoromethylphosphonate-contaning amino acid and its biological examination
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
タキプレシン誘導体をターゲッティングのキャリヤーとした抗エイズ薬の開発研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Development of highly efficient, selective, and practical synthetic method of pseudo-peptides possessing anti-tumour activity.
- Principal Investigator
  
  FUJII Nobutaka, 井深俊郎
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
シスチン含有ペプチドの高効率的合成法の開発研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
Synthesis of Peptide Isosteres with Strong Bombesin Antagonist Activity and Its Development to Anti-Cancer Agents
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
Development of Practical Synthetic Method for Phosphopeptides using Two-step Deprotecting Procedures
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
位置選択的ジスルフィド結合形成法を用いた抗HIVペプチドの構造活性相関研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
ペプチドの高効率位置選択的ジスルフィド結合形成法の開発研究Principal Investigator
- Principal Investigator
  
  玉村啓和
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Synthetic Study on Neurotrophins and Its Application for Development of Diagnostic Immunoassay Method for Senile Dementia
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
Development of efficient synthetic methods for peptides and syntheses of self-defense peptides possessing anti-virus activity
- Principal Investigator
  
  OTAKA Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Studies on the elucidantion of action mechanisms of tachyplesin analogs as anti-HIV peptides
- Principal Investigator
  
  FUJII Nobutaka
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY

[Book] Mid-Size Drugs Based on Peptides and Peptidomimetics: A New Drug Category2018
- Author(s)
  Tamamura H, Kobayakawa T, Ohashi N
- Total Pages
  100
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-16K15139
[Book] Mid-Size Drugs Based on Peptides and Peptidomimetics: A New Drug Category2018
- Author(s)
  Tamamura H, Kobayakawa T, Ohashi N
- Total Pages
  100
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H04652
[Book] Peptide-derived mid-sized anti-HIV agents. Amino Acids, Peptides and Proteins2017
- Author(s)
  Ohashi N, Tamamura H
- Total Pages
  30
- Publisher
  The Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-15H04652
[Book] Amino Acids, Peptides and Proteins2017
- Author(s)
  Nami Ohashi, & Hirokazu Tamamura
- Total Pages
  29
- Publisher
  The Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-16K15139
[Book] ペプチド医薬の最前線「監修　木曽良明・向井秀仁」2012
- Author(s)
  野村渉、田中智博、玉村啓和
- Publisher
  株式会社　シーエムシー出版　東京
- Data Source
  KAKENHI-PROJECT-24659043
[Book] ベプチド医薬の最前線「監修木曽良明・向井秀仁」2012
- Author(s)
  野村渉、田中智博、玉村啓和
- Publisher
  株式会社シーエムシー出版東京
- Data Source
  KAKENHI-PROJECT-24390024
[Book] 遺伝子医学MOOK[21]2012
- Author(s)
  野村渉、田中智博、相川春夫、玉村啓和
- Publisher
  株式会社　メディカルドゥ　大阪
- Data Source
  KAKENHI-PROJECT-24659043
[Book] Synthesis of HIV Gp41 Trimer Mimics Inducing Neutralizing Antibodies Based on Remodeling of Dynamic Structures of HIV-1 Envelope Proteins. Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Nomura W, Yamamoto N, Tamamura T, et al.
- Total Pages
  2
- Publisher
  Michal Lebl (Eds.), American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Synthesis and Evaluation of CXCR4-derived Peptides Targeting the Development of AIDS Vaccines. Proceedings of the 5th International Peptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Hashimoto C, Narumi T, Nomura W, Yamamoto N, Tamamura H
- Total Pages
  1
- Publisher
  Nobutaka Fujii and Yoshiaki Kiso (Eds.), The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Development of a Bivalent Ligand for a Chemokine Receptor CXCR4 by Utilizing Polyp roline Helix as a Linker. Proceedings of the 5th International Peptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Nomura W, Tanaka T, Tamamura H, et al.
- Total Pages
  1
- Publisher
  Nobutaka Fujii and Yoshiaki Kiso (Eds.), The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Studies for Optimum Design of Artificial Zinc Finger Recombinases by Evaluation of Effects of DNA Binding Affinity and Linker Components on Recombination Efficiency. Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Masuda A, Nomura, W, Ohba K, Yamamoto N, Tamamura H
- Total Pages
  2
- Publisher
  Michal Lebl (Eds.), American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Development of Bivalent Ligands for CXCR4 with Rigid Linkers and Application to Detection of Cancer Cells. Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Nomura W, Tanaka T, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Michal Lebl (Eds.), American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Synthesis and Evaluation of CXCR4-derived Peptides Targeting the Development of AIDS Vaccines. Proceedings of the 5th International Peptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Hashimoto C, Narumi T, Nomura W, Yamamoto N, Tamamura H
- Total Pages
  1
- Publisher
  Nobutaka Fujii and Yoshiaki Kiso (Eds.), The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Development of a Bivalent Ligand for a Chemokine Receptor CXCR4 by Utilizing Polyproline Helix as a Linker. Proceedings of the 5th International Peptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Nomura W, Tanaka T, Tamamura H, et al.
- Total Pages
  1
- Publisher
  Nobutaka Fujii and Yoshiaki Kiso (Eds.), The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Novel Tag-probe Pairs for Fluorescent Imaging of Proteins in Living Cells. Proceedings of the 5th International Peptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Nomura W, Ohashi N, Tamamura H, et al.
- Total Pages
  1
- Publisher
  Nobutaka Fujii and Yoshiaki Kiso (Eds.), The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Development of Bivalent Ligands for CXCR4 with Rigid Linkers and Application to Detection of Cancer Cells. Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Nomura W, Tanaka T, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Michal Lebl (Eds.), American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Synthesis of HIV Gp41 Trimer Mimics Inducing Neutralizing Antibodies Based on Remodeling of Dynamic Structures of HIV-1 Envelope Proteins. Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Nomura W, Yamamoto N, Tamamura T, et al.
- Total Pages
  2
- Publisher
  Michal Lebl (Eds.), American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Development of Bivalent Ligands forCXCR4 with Rigid Linkers and Application to Detection of Cancer Cells. Proceedings of the Twenty-Second American Peptide Symposium, Michal Lebl(Eds.)2011
- Author(s)
  Nomura W, Tamamura H, et. al.
- Publisher
  American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Development of a Bivalent Ligand for a Chemokine Receptor CXCR4 by Utilizing Polyproline Helix as a Linker. Proceedings of the 5th InternationalPeptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Nomura W, Tamamura H, et. al.
- Total Pages
  220
- Publisher
  The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Development of Bivalent Ligands for CXCR4 with Rigid Linkers and Application to Detection of Cancer Cells Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Nomura W, Tamamura H, et. al
- Publisher
  American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Novel Tag-probe Pairs for Fluorescent Imaging of Proteins in Living Cells. Proceedings of the 5th International Peptide Symposium in conjunction with the 47th Japanese Peptide Symposium2011
- Author(s)
  Nomura W, Ohashi N, Tamamura H, et al.
- Total Pages
  1
- Publisher
  Nobutaka Fujii and Yoshiaki Kiso (Eds.), The Japanese Peptide Society, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Studies for Optimum Design of Artificial Zinc Finger Recombinases by Evaluation of Effects of DNA Binding Affinity and Linker Components on Recombination Efficiency. Proceedings of the Twenty-Second American Peptide Symposium2011
- Author(s)
  Masuda A, Nomura, W, Ohba K, Yamamoto N, Tamamura H
- Total Pages
  2
- Publisher
  Michal Lebl (Eds.), American Peptide Society, San Diego
- Data Source
  KAKENHI-PROJECT-22659021
[Book] From Reverse to Forward Chemical Genomics: Development of Anti-HIVAgent.Peptide Science 20092010
- Author(s)
  Tanaka T, Nomura W, Yamamoto N, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-22659021
[Book] ペプチド科学と生化学の接点(ペプチドミメティックによる創薬研究, 生化学特集号)(82巻6号)2010
- Author(s)
  鳴海哲夫, 玉村啓和
- Total Pages
  9
- Publisher
  日本生化学会東京
- Data Source
  KAKENHI-PROJECT-22659021
[Book] From Reverse to Forward Chemical Genomics : Development of Anti-HIV Agent Peptide Science 20092010
- Author(s)
  Tanaka T, Nomura W, Yamamoto N, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Caged DAG-Lactones for Study of Cellular Signaling in a Spatial-andTemporal Specific Manner.Peptide Science 20092010
- Author(s)
  Nomura W, Furuta T, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-22659021
[Book] エピジェネティクな遺伝子発現制御のためのDNAメチル化酵素の創製, 生化学ミニレビュウ 82巻-85巻2010
- Author(s)
  野村渉, 増田朱美, 玉村啓和
- Total Pages
  5
- Publisher
  日本生化学会東京
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Fluorescnt-Based Orthogonal Sensing Methods for Double Ealuation in PKC Ligands Screening Peptide Science 20092010
- Author(s)
  Ohashi N, Nomura W, Lewin NE, Blumberg PM, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-21390029
[Book] ペプチドミメティックによる創薬研究2010
- Author(s)
  鳴海哲夫,玉村啓和
- Publisher
  日本生化学会東京
- Data Source
  KAKENHI-PROJECT-21390029
[Book] エピジェネティクな遺伝子発現制御のためのDNAメチル化酵素の創製,生化学ミニレビュウ(82巻 5巻)2010
- Author(s)
  野村渉, 増田朱美, 玉村啓和
- Total Pages
  5
- Publisher
  日本生化学会東京
- Data Source
  KAKENHI-PROJECT-22659021
[Book] 「ペプチド科学と生化学の接点」(ペプチドミメティックによる創薬研究, 生化学特集号)82巻6号2010
- Author(s)
  鳴海哲夫, 玉村啓和
- Total Pages
  9
- Publisher
  日本生化学会東京
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Synthesis and Evaluation of Artificial Antigen Peptide Based on theTrimeric Form of HIV Fusion Protein.Peptide Science 20092010
- Author(s)
  Ohya A, Nakahara T, Nomura W, Yamamoto N, Tamamura H, et al.
- Total Pages
  3
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Fluorescnt-Based Orthogonal Sensing Methods for Double Ealuation in PKC Ligands Screening.Peptide Science 20092010
- Author(s)
  Ohashi N, Nomura W, Lewin NE, Blumberg PM, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Caged DAG-Lactones for Study of Cellular Signaling in a Spatial-and Temporal Specific Manner Peptide Science 20092010
- Author(s)
  Nomura W, Furuta T, Tamamura H, et al.
- Total Pages
  2
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-21390029
[Book] From Reverse to Forward Chemical Genomics Development of Anti-HIV Agent. Peptide Science 20092010
- Author(s)
  Tanaka T, Nomura W, Yamamoto N, Tamamura H, et. al
- Publisher
  The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-21390029
[Book] ペプチドミメティックによる創薬研究,生化学特集号「ペプチド科学と生化学の接点」2010
- Author(s)
  鳴海哲夫,玉村啓和
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-22659021
[Book] Synthesis and Evaluation of Artificial Antigen Peptide Based on the Trimeric Form of HIV Fusion Protein Peptide Science 20092010
- Author(s)
  Ohya A, Nakahara T, Nomura W, Yamamoto N, Tamamura H, et al.
- Total Pages
  3
- Publisher
  Kouji Okamoto (Eds.), The Japanese peptide Society, Osaka
- Data Source
  KAKENHI-PROJECT-21390029
[Book] 種々の作用点をターゲットとした抗HIV剤の創製2009
- Author(s)
  玉村啓和
- Publisher
  日本エイズ学会
- Data Source
  KAKENHI-PROJECT-22659021
[Book] 種々の作用点をターゲットとした抗HIV剤の創製2009
- Author(s)
  玉村啓和
- Publisher
  日本エイズ学会誌(日本エイズ学会)
- Data Source
  KAKENHI-PROJECT-21390029
[Book] Peptide Science 20072008
- Author(s)
  H. Tamamura, et al.
- Total Pages
  4
- Publisher
  The Japanese peptide Society
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Low-molecular-weight Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins2023
- Author(s)
  Kobayakawa, T., M. Yokoyama, K. Tsuji, M. Fujino, M. Kurakami, T. Onishi, S. Boku, T. Ishii, Y.Miura, K. Shimohara, Y. Kishihara, N. Ohashi, O. Kotani, T. Murakami, H. Sato and H. Tamamura
- Journal Title
  
  RSC Advances
  
  Volume: 13 Issue: 3 Pages: 2156-2167
- DOI
  10.1039/d2ra06837k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08615, KAKENHI-PROJECT-22K15243
[Journal Article] Dimerized fusion inhibitor peptides targeting the HR1?HR2 interaction of SARS-CoV-22023
- Author(s)
  Tsuji Kohei、Baffour-Awuah Owusu Kofi、Miura Yutaro、Ishii Takahiro、Shinohara Kouki、Kobayakawa Takuya、Emi Akino、Nakano Takashi、Suzuki Youichi、Tamamura Hirokazu
- Journal Title
  
  RSC Advances
  
  Volume: 13 Issue: 13 Pages: 8779-8793
- DOI
  10.1039/d2ra07356k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15243, KAKENHI-PROJECT-20H03362
[Journal Article] Sensitivity to a CD4 mimic of a consensus clone of monkey-adapted CCR5-tropic SHIV-MK38C2023
- Author(s)
  Matsuura Kanako、Yamaura Mizuki、Sakawaki Hiromi、Himeno Ai、Pisil Yalcin、Kobayakawa Takuya、Tsuji Kohei、Tamamura Hirokazu、Matsushita Shuzo、Miura Tomoyuki
- Journal Title
  
  Virology
  
  Volume: 578 Pages: 171-179
- DOI
  10.1016/j.virol.2022.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15243, KAKENHI-PROJECT-20H03362, KAKENHI-PROJECT-21H02970
[Journal Article] Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates2023
- Author(s)
  Matsumoto Kaho、Kuwata Takeo、Tolbert William D.、Richard Jonathan、Ding Shilei、Prevost Jeremie、Takahama Shokichi、Judicate George P.、Ueno Takamasa、Nakata Hirotomo、Kobayakawa Takuya、Tsuji Kohei、Tamamura Hirokazu、Smith Amos B.、Pazgier Marzena、Finzi Andres、Matsushita Shuzo
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 1
- DOI
  10.1128/jvi.01638-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05989, KAKENHI-PROJECT-22K15243, KAKENHI-PROJECT-20H03362, KAKENHI-PROJECT-21H02970, KAKENHI-PROJECT-21K19657
[Journal Article] Development of ultra-high affinity bivalent ligands targeting the polo-like kinase 12022
- Author(s)
  Tsuji Kohei、Hymel David、Ma Buyong、Tamamura Hirokazu、Nussinov Ruth、Burke Terrence R.
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 3 Issue: 9 Pages: 1111-1120
- DOI
  10.1039/d2cb00153e
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15243, KAKENHI-PROJECT-20H03362
[Journal Article] Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors2022
- Author(s)
  Tsuji Kohei、Kobayakawa Takuya、Konno Kiju、Masuda Ami、Takahashi Kohei、Ohashi Nami、Yoshimura Kazuhisa、Kuwata Takeo、Matsushita Shuzo、Harada Shigeyoshi、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 56 Pages: 116616-116616
- DOI
  10.1016/j.bmc.2022.116616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-21H02970, KAKENHI-PROJECT-21K08501, KAKENHI-PROJECT-20H03362
[Journal Article] Hybrids of small CD4 mimics and gp41-related peptides as dual-target HIV entry inhibitors2022
- Author(s)
  Wang Rongyi、Tsuji Kohei、Kobayakawa Takuya、Liu Yishan、Yoshimura Kazuhisa、Matsushita Shuzo、Harada Shigeyoshi、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 76 Pages: 117083-117083
- DOI
  10.1016/j.bmc.2022.117083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08501, KAKENHI-PROJECT-22K15243, KAKENHI-PROJECT-20H03362, KAKENHI-PROJECT-21H02970
[Journal Article] Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors2021
- Author(s)
  Kobayakawa Takuya、Tsuji Kohei、Konno Kiju、Himeno Ai、Masuda Ami、Yang Tingting、Takahashi Kohei、Ishida Yusuke、Ohashi Nami、Kuwata Takeo、Matsumoto Kaho、Yoshimura Kazuhisa、Sakawaki Hiromi、Miura Tomoyuki、Harada Shigeyoshi、Matsushita Shuzo、Tamamura Hirokazu
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 3 Pages: 1481-1496
- DOI
  10.1021/acs.jmedchem.0c01153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H02854, KAKENHI-PROJECT-18K06032, KAKENHI-PROJECT-18K08458, KAKENHI-PROJECT-19K22488, KAKENHI-PROJECT-19H03146, KAKENHI-PROJECT-21K05989, KAKENHI-PROJECT-21K08501
[Journal Article] Fluorescence Resonance Energy Transfer-based Screening for Protein Kinase C Ligands Using 6-methoxynaphthalene-labeled 1,2-diacylglycerol-lactones2021
- Author(s)
  Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nami Ohashi, Wataru Nomura, Hirokazu Tamamura
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 19 Issue: 38 Pages: 8264-8271
- DOI
  10.1039/d1ob00814e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21253, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-20H03362, KAKENHI-PROJECT-19H02827
[Journal Article] Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application2021
- Author(s)
  Kobayakawa Takuya、Azuma Chika、Watanabe Yuki、Sawamura Shunsuke、Taniguchi Atsuhiko、Hayashi Yoshio、Tsuji Kohei、Tamamura Hirokazu
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 7 Pages: 5091-5101
- DOI
  10.1021/acs.joc.0c03019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07001, KAKENHI-PROJECT-19K16312, KAKENHI-PROJECT-20H03362
[Journal Article] Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment2021
- Author(s)
  Tsuji Kohei、Wang Rongyi、Kobayakawa Takuya、Owusu Kofi Baffour-Awuah、Fujino Masayuki、Kaneko Moemi、Yamamoto Naoki、Murakami Tsutomu、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 30 Pages: 115923-115923
- DOI
  10.1016/j.bmc.2020.115923
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins2021
- Author(s)
  Kobayakawa Takuya、Yokoyama Masaru、Tsuji Kohei、Fujino Masayuki、Kurakami Masaki、Boku Sayaka、Nakayama Miyuki、Kaneko Moemi、Ohashi Nami、Kotani Osamu、Murakami Tsutomu、Sato Hironori、Tamamura Hirokazu
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 2 Pages: 208-208
- DOI
  10.3390/biom11020208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators2021
- Author(s)
  Matsuda Kouki、Kobayakawa Takuya、Kariya Ryusho、Tsuchiya Kiyoto、Ryu Shoraku、Tsuji Kohei、Ishii Takahiro、Gatanaga Hiroyuki、Yoshimura Kazuhisa、Okada Seiji、Hamada Akinobu、Mitsuya Hiroaki、Tamamura Hirokazu、Maeda Kenji
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 12 Pages: 636276-636276
- DOI
  10.3389/fmicb.2021.636276
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-20K17480, KAKENHI-PROJECT-19K22488, KAKENHI-PROJECT-20H03362
[Journal Article] Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment2020
- Author(s)
  Tsuji Kohei、Owusu Kofi Baffour-Awuah、Kobayakawa Takuya、Wang Rongyi、Fujino Masayuki、Kaneko Moemi、Yamamoto Naoki、Murakami Tsutomu、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 11 Pages: 115488-115488
- DOI
  10.1016/j.bmc.2020.115488
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Bivalent HIV-1 fusion inhibitors based on peptidomimetics2020
- Author(s)
  Kobayakawa T, Ebihara K, Tsuji K, Kawada T, Fujino M, Honda Y, Ohashi N, Murakami T, Tamamura H
- Journal Title
  
  Bioorg Med Chem.
  
  Volume: 28 Pages: 115812-115812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07158
[Journal Article] Bivalent HIV-1 fusion inhibitors based on peptidomimetics2020
- Author(s)
  Kobayakawa Takuya、Ebihara Kento、Tsuji Kohei、Kawada Takuma、Fujino Masayuki、Honda Yuzuna、Ohashi Nami、Murakami Tsutomu、Tamamura Hirokazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 24 Pages: 115812-115812
- DOI
  10.1016/j.bmc.2020.115812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08558, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19K22488
[Journal Article] Synthesis of Hydrophilic Caged DAG-lactone for Chemical Biology Applications2020
- Author(s)
  Takuya Kobayakawa, Hikaru Takano, Takahiro Ishii, Kohei Tsuji, Nami Ohashi, Wataru Nomura, Toshiaki Furuta, Hirokazu Tamamura
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 18 Issue: 22 Pages: 4217-4223
- DOI
  10.1039/d0ob00807a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21253, KAKENHI-PROJECT-20K15951, KAKENHI-PROJECT-19H02827, KAKENHI-PROJECT-19K22488, KAKENHI-PROJECT-16H06280
[Journal Article] Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal.2019
- Author(s)
  Kouki Matsuda, Takuya Kobayakawa, Kiyoto Tsuchiya, Shin-ichiro Hattori, Wataru Nomura, Hiroyuki Gatanaga, Kazuhisa Yoshimura, Shinichi Oka, Yasuyuki Endo, Hirokazu Tamamura, Hiroaki Mitsuya, Kenji Maeda
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 1 Pages: 116-129
- DOI
  10.1074/jbc.ra118.005798
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-19K22488
[Journal Article] Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands2019
- Author(s)
  3.Sakyiamah MM., Kobayakawa T., Fujino M., KonnoM., Narumi T., Tanaka T., Nomura W., Yamamoto N., Murakami T., and Tamamura H.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 2 Issue: 6 Pages: 1130-1138
- DOI
  10.1016/j.bmc.2019.02.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07158, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-15K10043, KAKENHI-PROJECT-16K01931
[Journal Article] Dimeric C34 derivatives linked through disulfide bridges as new HIV-1 fusion inhibitors.2019
- Author(s)
  Kobayakawa, T., K. Ebihara, Y. Honda, M. Fujino, W. Nomura, N. Yamamoto, T. Murakami, and H. Tamamura
- Journal Title
  
  Chembiochem.
  
  Volume: なし Issue: 16 Pages: 2101-2108
- DOI
  10.1002/cbic.201900187
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07158, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-19H02827
[Journal Article] Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application2018
- Author(s)
  Takuya Kobayakawa, Yudai Matsuzaki, Kentaro Hozumi, Wataru Nomura, Motoyoshi Nomizu, Hirokazu Tamamura
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 9 Issue: 1 Pages: 6-10
- DOI
  10.1021/acsmedchemlett.7b00234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01931, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-16J08904, KAKENHI-PROJECT-15K01318
[Journal Article] Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization2017
- Author(s)
  Hikaru Takano, Tetsuo Narumi, Wataru Nomura, Hirokazu Tamamura
- Journal Title
  
  J. Org. Chem.
  
  Volume: 82 Issue: 5 Pages: 2739-2744
- DOI
  10.1021/acs.joc.6b02656
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16H06217, KAKENHI-PROJECT-15J04754, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K15139, KAKENHI-PROJECT-16K15142, KAKENHI-PROJECT-15H04652
[Journal Article] Stereoselective Synthesis of Xaa-Yaa Type (Z)-Chloroalkene Dipeptide Isosteres via Efficient Utilization of Organocopper Reagents Mediated Allylic Alkylation2017
- Author(s)
  Kobayakawa T, Tamamura H
- Journal Title
  
  Tetrahedron
  
  Volume: 73 Issue: 30 Pages: 4464-4471
- DOI
  10.1016/j.tet.2017.06.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04652
[Journal Article] Bivalent 14-mer Peptide Ligands of CXCR4 with Polyproline Linkers with Anti-Chemotactic Activity against Jurkat Cells2017
- Author(s)
  Tomohiro Tanaka, Toru Aoki, Wataru Nomura, Hirokazu Tamamura
- Journal Title
  
  J. Pept. Sci.
  
  Volume: 印刷中 Issue: 7-8 Pages: 574-580
- DOI
  10.1002/psc.2946
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K18915, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-16K15139
[Journal Article] Development of Anti-HIV Peptides Based on a Viral Capsid Protein2017
- Author(s)
  Takaaki Mizuguchi, Nami Ohashi, Daichi Matsumoto, Chie Hashimoto, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura
- Journal Title
  
  Biopolymers: Peptide Science
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1002/bip.22920
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-26460566, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K15139, KAKENHI-PROJECT-18K07158
[Journal Article] Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-lactones as PKC Ligands2017
- Author(s)
  Nami Ohashi, Ryosuke Kobayashi, Wataru Nomura, Takuya Kobayakawa, Agnes Czikora, Brienna Herold, Nancy E. Lewin, Peter M. Blumberg, Hirokazu Tamamura
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 28 Issue: 8 Pages: 2135-2144
- DOI
  10.1021/acs.bioconjchem.7b00299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01931, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-16J08904, KAKENHI-PROJECT-16K15139
[Journal Article] Functional Evaluation of Fluorescent-Labeled Derivatives of an Inhibitory Peptide against EGF Receptor Dimerization2016
- Author(s)
  Mizuguchi T., Toyama K., Ishida Y., Nomura W., Tamamura H.
- Journal Title
  
  Peptide Science
  
  Volume: 2015 Pages: 41-42
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26893061
[Journal Article] Exploration of Labeling of Near Infrared Dyes on the Polyproline Linker for Bivalent-Type CXCR4 Ligands.2016
- Author(s)
  Wataru Nomura, Haruo Aikawa, Shohei Taketomi, Miho Tanabe, Takaaki Mizuguchi & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 21 Pages: 6967-6973
- DOI
  10.1016/j.bmc.2015.09.040
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-15J05835, KAKENHI-PROJECT-26670053
[Journal Article] Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.2016
- Author(s)
  Nami Ohashi1, Shigeyoshi Harada, Takaaki Mizuguchi1, Yu Irahara1, Yuko Yamada, Misato Kotani, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura.
- Journal Title
  
  Chem Med Chem
  
  Volume: 19 Issue: 8 Pages: 940-946
- DOI
  10.1002/cmdc.201500590
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08125, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-15H04870, KAKENHI-PROJECT-26670053, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K15139
[Journal Article] A minimally cytotoxic CD4 mimic as an HIV entry inhibitor2016
- Author(s)
  Takaaki Mizuguchi, Shigeyoshi Harada, Tomoyuki Miura, Nami Ohashi, Tetsuo Narumi, Hiromi Mori, Yu Irahara, Yuko Yamada, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 26 Issue: 2 Pages: 397-400
- DOI
  10.1016/j.bmcl.2015.11.103
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26105721, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-15H04870, KAKENHI-PROJECT-26670053, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16H04682, KAKENHI-PROJECT-15K08125, KAKENHI-PROJECT-16K01931
[Journal Article] Evaluation of Fluorescein-Labeled Derivatives of a Peptide Inhibitor of the EGF Receptor Dimerization2016
- Author(s)
  Kei Toyama, Takaaki Mizuguchi, Wataru Nomura, Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Issue: 16 Pages: 3406-3412
- DOI
  10.1016/j.bmc.2016.05.026
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K15139
[Journal Article] Studies on a Novel Delivery Peptide Derived from the Dimerization Arm of EGF Receptor2016
- Author(s)
  Toyama K., Mizuguchi T., Ishida Y., Nomura W., Tamamura H.
- Journal Title
  
  Peptide Science
  
  Volume: 2015 Pages: 249-250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26893061
[Journal Article] Efficient synthesis of Xaa-Gly type (Z)-chloroalkene dipeptide isosteres via organocuprate mediated reduction2016
- Author(s)
  Takuya Kobayakawa, Hirokazu Tamamura
- Journal Title
  
  Tetrahedron
  
  Volume: 72 Issue: 32 Pages: 4968-4971
- DOI
  10.1016/j.tet.2016.06.080
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J08904, KAKENHI-PROJECT-16K15139
[Journal Article] Trivalent Lignds for CXCR4 Bearing Polyproline Linkers Show Specific Recognition for Cells with Increased CXCR4 Expression.2015
- Author(s)
  Wataru Nomura, Taisuke Koseki, Nami Ohashi, Takaaki Mizuguchi & Hirokazu Tamamura
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 13 Issue: 32 Pages: 8734-8739
- DOI
  10.1039/c5ob00891c
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-26670053
[Journal Article] Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins2015
- Author(s)
  Mizuguchi T, Ohashi N, Nomura W, Komoriya M, Hashimoto C, Yamamoto N, Murakami T, and Tamamura H
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Pages: 4423-4427
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460566
[Journal Article] Studies on Identification of Active Sites of an Inhibitory Cyclic Peptide against EGF Receptor Dimerization2015
- Author(s)
  Mizuguchi T, Yamazaki Y, Kobayashi K, Ooe H, Iida M, Ninomiya R, Saito K, Akaji K, Tamamura H.
- Journal Title
  
  Peptide Science
  
  Volume: 2014 Pages: 163-164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26893061
[Journal Article] Anti-HIV Screening for Cell-Penetrating Peptides Using Chloroquine and Identification of Anti-HIV Peptides Derived from Matrix Proteins.2015
- Author(s)
  Takaaki Mizuguchi, Nami Ohashi, Wataru Nomura, Mao Komoriya, Chie Hashimoto, Naoki Yamamoto, Tsutomu Murakami & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 15 Pages: 4423-4427
- DOI
  10.1016/j.bmc.2015.06.020
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-26670053
[Journal Article] An In-cell Fluorogenic Tag-probe System for Protein Dynamics Imaging Enabled by Cell-Penetrating Peptides.2015
- Author(s)
  Wataru Nomura, Nami Ohashi, Atsumi Mori & Hirokazu Tamamura
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 26 Issue: 6 Pages: 1080-1085
- DOI
  10.1021/acs.bioconjchem.5b00131
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-26670053
[Journal Article] Utilization of the Heavy Atom Effect for the Development of a Photosensitive 8-Azacoumarin-Type Photolabile Protecting Group2015
- Author(s)
  Hikaru Takano, Tetsuo Narumi, Wataru Nomura, Toshiaki Furuta, and Hirokazu Tamamura
- Journal Title
  
  Organic Letters
  
  Volume: 17 Issue: 21 Pages: 5372-5375
- DOI
  10.1021/acs.orglett.5b02720
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26105721, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-15J04754, KAKENHI-PROJECT-26670053, KAKENHI-PROJECT-26282219
[Journal Article] Development of a Traceable Linker Containing a Thiol-responsive Amino Acid for the Enrichment and Selective Labelling of Target Proteins.2014
- Author(s)
  Yamamoto J, Denda M, Maeda N, Kita M, Komiya C, Tanaka T, Nomura W, Tamamura H, Sato Y, Yamauchi A, Shigenaga A, Otaka A.
- Journal Title
  
  Org Biomol Chem
  
  Volume: 12-23
- NAID
  120006510952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670053
[Journal Article] Isostere-Based Design of 8-Azacoumarin-Type Photolabile Protecting Groups: A Hydrophilicity-Increasing Strategy for Coumarin-4-ylmethyls2014
- Author(s)
  Narumi, T., Takano, H., Ohashi, N., Suzuki, A., Furuta, T., Tamamura, H.
- Journal Title
  
  Org. Lett.
  
  Volume: 16 Issue: 4 Pages: 1184-1187
- DOI
  10.1021/ol5000583
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24105507, KAKENHI-PUBLICLY-24121724, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-24790107
[Journal Article] Screening for Protein Kinase C Ligands Using Fluorescence Resonance Energy Transfer.2014
- Author(s)
  Nami Ohashi, Wataru Nomura, Natsuki Minato & Hirokazu Tamamura
- Journal Title
  
  Chem. Pharm. Bull.,
  
  Volume: 62-10 Pages: 1019-1025
- NAID
  130004677396
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390024
[Journal Article] Development of a Fluoride-responsive Amide Bond Cleavage Device that is Potentially Applicable to a Traceable Linker.2014
- Author(s)
  5.Jun Yamamoto, Nami Maeda, Chiaki Komiya, Tomohiro Tanaka, Masaya Denda, Koji Ebisuno, Wataru Nomura, Hirokazu Tamamura, Youichi Sato, Aiko Yamauchi, Akira Shigenaga & Akira Otaka
- Journal Title
  
  Tetrahedron,
  
  Volume: 70-34 Pages: 5122-5127
- NAID
  120006493358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390024
[Journal Article] Imidazolium Salt-Catalyzed Friedel-Crafts-Type Conjugate Addition of Indoles: Analysis of Indole/Imidazolium Complex by High Level ab Initio Calculations.2014
- Author(s)
  Narumi T, Tsuzuki S, Tamamura H.
- Journal Title
  
  Asian J Org Chem
  
  Volume: 3-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670053
[Journal Article] Anti-HIV-1 Peptide Derivatives Based on the HIV-1 Co-receptor CXCR4.2013
- Author(s)
  Hashimoto C, Nomura W, Narumi T, Fujino M, Tsutsumi H, Haseyama M, Yamamoto N, Murakami T, Tamamura H.
- Journal Title
  
  ChemMedChem
  
  Volume: 8 Issue: 10 Pages: 1668-1672
- DOI
  10.1002/cmdc.201300289
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24119506, KAKENHI-PROJECT-24390024, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-25410171
[Journal Article] CD4 Mimics as HIV Entry Inhibitors : Lead Optimization Studies of the Aromatic Substituents2013
- Author(s)
  Tetsuo Narumi, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Yuki Hirota, Nami Ohashi, Chie Hashimoto, Wataru Nomura, Shuzo Matsushita & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21(9)
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] A CD4 Mimic as an HIV Entry Inhibitors: Pharmacokinetics2013
- Author(s)
  Hashimoto, C., Narumi, T., Otsuki, H., Hirota, Y., Arai, H., Yoshimura, K., Harada, S., Ohashi, N., Nomura, W., Miura, T., Igarashi, T., Matsuhita, S., Tamamura, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 24 Pages: 7884-7889
- DOI
  10.1016/j.bmc.2013.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24105507, KAKENHI-PUBLICLY-24119506, KAKENHI-PROJECT-24590199, KAKENHI-PROJECT-24591484, KAKENHI-PROJECT-24591485, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-24790107, KAKENHI-PROJECT-25410171
[Journal Article] A CD4 Mimic as an HIV Entry Inhibitor : Pharmacokinetics2013
- Author(s)
  Chie Hashimoto, Tetsuo Narumi, Hiroyuki Otsuki, Yuki Hirota, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Nami Ohashi, Wataru Nomura, Tomoyuki Miura, Tatsuhiko Igarashi, Shuzo Matsushita & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21(24)
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Anti-HIV-1 Peptide Derivatives Based on the HIV-1 Co-receptor CXCR42013
- Author(s)
  Chie Hashimoto, Wataru Nomura, Tetsuo Narumi, Masayuki Fujino, Hiroshi Tsutsumi, Masaki Haseyama, Naoki Yamamoto, Tsutomu Murakami & Hirokazu Tamamura
- Journal Title
  
  ChemMedChem
  
  Volume: 8(10) Pages: 1668-1672
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Cell-Permeable Stapled Peptides Based on HIV-1 Integrase Inhibitors Derived from HIV-1 Gene Product2013
- Author(s)
  Wataru Nomura, Haruo Aikawa, Nami Ohashi, Emiko Urano, Mathieu Metifiot, Masayuki Fujino, Kasthuraiah Maddali, Taro Ozaki, Ami Nozue, Tetsuo Narumi, Chie Hashimoto, Tomohiro Tanaka, Yves Pommier, Naoki Yamamoto, Jun Komano, Tsutomu Murakami & Hirokazu Tamamura
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 8(10)
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] CXCR4-derived synthetic peptides inducing anti-HIV-1 antibodies.2013
- Author(s)
  Hashimoto C, Nomura W, Narumi T, Fujino M, Nakahara T, Yamamoto N, Murakami T, Tamamura H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 22 Pages: 6878-6885
- DOI
  10.1016/j.bmc.2013.09.037
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24119506, KAKENHI-PROJECT-24390024, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-25410171
[Journal Article] CD4 Mimics as HIV Entry Inhibitors: Lead Optimization Studies of the Aromatic Substituents.2013
- Author(s)
  Narumi, T., Arai, H., Yoshimura, K., Harada, S., Hirota, Y., Ohashi, N., Hashimoto, C.. Nomura, W., Matsushita, S. and Tamamura, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 8 Issue: 9 Pages: 2518-2526
- DOI
  10.1016/j.bmc.2013.02.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05127, KAKENHI-PUBLICLY-24105507, KAKENHI-PROJECT-24590199, KAKENHI-PROJECT-24591484, KAKENHI-PROJECT-24591485, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-24790107
[Journal Article] Low Molecular Weight CXCR4 Ligands with Variable Spacers.2013
- Author(s)
  Tetsuo Narumi, Haruo Aikawa, Tomohiro Tanaka, Chie Hashimoto, Nami Ohashi, Wataru Nomura, Takuya Kobayakawa, Hikaru Takano, Yuki Hirota, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  ChemMedChem
  
  Volume: 8 Pages: 118-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Multimerized CHR-derived Peptides as HIV-1 Fusion Inhibitors2013
- Author(s)
  Wataru Nomura, Chie Hashimoto, Takaharu Suzuki, Nami Ohashi, Masayuki Fujino, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21(15)
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] CXCR4-derived Synthetic Peptides Inducing Anti-HIV-1 Antibodies2013
- Author(s)
  Chie Hashimoto, Wataru Nomura, Tetsuo Narumi, Masayuki Fujino, Toru Nakahara, Naoki Yamamoto, Tsutomu Murakami & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21(22)
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Generation of a replication-competent simianhuman immunodeficiency virus, the neutralisation sensitivity of which can be enhanced in the presence of a small molecule CD4 mimic.2013
- Author(s)
  Otsuki, H., Hishiki, T., Miura, T., Hashimoto, C., Narumi, T., Tamamura, H., Yoshimura, K., Matsushita, S., and Igarashi, T.
- Journal Title
  
  J. Gen. Virol.
  
  Volume: 94 Issue: 12 Pages: 2710-2716
- DOI
  10.1099/vir.0.055590-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658240, KAKENHI-PUBLICLY-24105507, KAKENHI-PROJECT-24591484, KAKENHI-PROJECT-24591485, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-24790107
[Journal Article] Low Molecular Weight CXCR4 Ligands with Variable Spacers2013
- Author(s)
  Tetsuo Narumi, Haruo Aikawa, Tomohiro Tanaka, Chie Hashimoto, Nami Ohashi, Wataru Nomura, Takuya Kobayakawa, Hikaru Takano, Yuki Hirota, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  ChemMedChem
  
  Volume: 8(1) Pages: 118-124
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Cell-Permeable Stapled Peptides Based on HIV-1 Integrase Inhibitors Derived from HIV-1 Gene Products.2013
- Author(s)
  Nomura W, Aikawa H, Ohashi N, Urano E, Metifiot M, Fujino M, Maddali K, Ozaki T, Nozue A, Narumi T, Hashimoto C, Tanaka T, Pommier Y, Yamamoto N, Komano JA, Murakami T, Tamamura H.
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 8 Issue: 10 Pages: 2235-2244
- DOI
  10.1021/cb400495h
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24119506, KAKENHI-PROJECT-24390024, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-25410171
[Journal Article] Multimerized CHR-Derived Peptides as HIV-1 Fusion Inhibitors.2013
- Author(s)
  Nomura W, Hashimoto C, Suzuki T, Ohashi N, Fujino M, Murakami T, Yamomoto N, Tamamura H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Issue: 15 Pages: 4452-4458
- DOI
  10.1016/j.bmc.2013.05.060
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24119506, KAKENHI-PROJECT-24659043, KAKENHI-PROJECT-25410171
[Journal Article] Evaluation of a Synthetic C34 Trimer of HIV-1 gp41 as AIDS Vaccines2012
- Author(s)
  Hashimoto, C., Nomura, W., Ohya, A., Urano, E., Miyauchi, K., Narumi, T., Aikawa, H., Komano, J.A., Yamamoto, N., Tamamura, H.
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: (in press) Issue: 10 Pages: 3287-3291
- DOI
  10.1016/j.bmc.2012.03.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05127, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-23710251, KAKENHI-PROJECT-24310146, KAKENHI-PUBLICLY-24119506
[Journal Article] Evaluation of a Synthetic C34 Trimer of HIV-1 gp41 as AIDS Vaccines2012
- Author(s)
  Hashimoto C, Nomura W, Yamamoto N, Tamamura H, et al.
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Pharmacophore-based Small Molecule CXCR4 Ligands.2012
- Author(s)
  Tetsuo Narumi, Tomohiro Tanaka, Chie Hashimoto, Wataru Nomura, Haruo Aikawa, Akira Sohma, Kyoko Itotani, Miyako Kawamata, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Pages: 4169-4172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Stereoselective Formation of Trisubstituted (Z)-Chloroalkenes Adjacent to a Tertiary Carbon Stereogenic Center by Organocuprate-Mediated Reduction/Alkylation2012
- Author(s)
  Tetsuo Narumi, Takuya Kobayakawa, Haruo Aikawa, Shunsuke Seike & Hirokazu Tamamura
- Journal Title
  
  Org. Lett.
  
  Volume: 14(17) Pages: 4490-4493
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Evaluation of a Synthetic C34 Trimer of HIV-1 gp41 as AIDS Vaccines2012
- Author(s)
  Hashimoto C, Nomura W, Tamamura H, 他7人、10番目
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Conjugation of Cell-penetrating Peptides Leads to Identification of Anti-HIV Peptides from Matrix Proteins2012
- Author(s)
  T.Narumi, T.Tanaka, et al
- Journal Title
  
  Biochemistry & Medicinal Chemistry
  
  Volume: 20 Issue: 4 Pages: 1468-1474
- DOI
  10.1016/j.bmc.2011.12.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05336, KAKENHI-PROJECT-11J05127, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-23710251, KAKENHI-PUBLICLY-24105507
[Journal Article] Effects of DNA Binding of Zinc Finger and Linkers for Domain Fusion on Catalytic Activity of Sequence-Specific ChimericRecombinases Determined by a Facile Fluorescent System2012
- Author(s)
  Nomura W, Yamamoto N, Tamamura H, 他5人、8番目
- Journal Title
  
  Biochemistry
  
  Volume: 51巻 Pages: 1510-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Evaluation of aSynthetic C34 Trimer of HIV-1 gp41 asAIDS Vaccines2012
- Author(s)
  Hashimoto C, Nomura W, Tamamura H(他7人、10番目)
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Effects of DNA Binding of Zinc Finger and Linkers for Domain Fusion on Catalytic Activity of Sequence-Specific Chimeric Recombinases Determined by a Facile Fluorescent System2012
- Author(s)
  Nomura, W., Masuda, A., Ohba, K., Urabe, A., Ito, N., Ryo, A., Yamamoto, N., Tamamura, H.
- Journal Title
  
  Biochemistry
  
  Volume: 51 Issue: 7 Pages: 1510-1517
- DOI
  10.1021/bi201878x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05142, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-21390144, KAKENHI-PROJECT-22659021, KAKENHI-PUBLICLY-23117526, KAKENHI-PROJECT-23710251
[Journal Article] Stereoselective Formation ofTrisubstituted (Z)-Chloroalkenes Adjacent to a Tertiary Carbon Stereogenic Center by Organocuprate-Mediated Reduction/Alkylation.2012
- Author(s)
  Tetsuo Narumi, Takuya Kobayakawa, Haruo Aikawa, Shunsuke Seike & Hirokazu Tamamura
- Journal Title
  
  Org. Lett.
  
  Volume: 14 Pages: 4490-4493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Evaluation of a Synthetic C34 Trimer of HIV-1 gp41 as AIDS Vaccines2012
- Author(s)
  Chie Hashimoto, Wataru Nomura, Aki Ohya, Emiko Urano, Kosuke Miyauchi, Tetsuo Narumi, Haruo Aikawa, Jun A. Komano, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20(10)
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Pharmacophore-based Small Molecule CXCR4 Ligands2012
- Author(s)
  Tetsuo Narumi, Tomohiro Tanaka, Chie Hashimoto, Wataru Nomura, Haruo Aikawa, Akira Sohma, Kyoko Itotani, Miyako Kawamata, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22(12) Pages: 4169-4172
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase of Inhibition Potency2012
- Author(s)
  W.Nomura, T.Tanaka, et.al.
- Journal Title
  
  Chem Med Chem
  
  Volume: 7 Issue: 2 Pages: 205-208
- DOI
  10.1002/cmdc.201100542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05336, KAKENHI-PROJECT-11J05127, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-23710251, KAKENHI-PROJECT-24390024
[Journal Article] Pharmacophore-basedSmall Molecule CXCR4 Ligand2012
- Author(s)
  Narumi T, Nomura W, Tamamura H(他8人、11番目)
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Evaluation of a Synthetic C34 Trimer of HIV-1 gp41 as AIDS Vaccines.2012
- Author(s)
  Chie Hashimoto, Wataru Nomura, Aki Ohya, Emiko Urano, Kosuke Miyauchi, Tetsuo Narumi, Haruo Aikawa, Jun A. Komano, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Pharmacophore-based Small Molecule CXCR4 Ligands2012
- Author(s)
  Narumi T, Nomura W, Tamamura H, 他8人、11番目
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Effects of DNA Binding of Zinc Finger and Linkers for Domain Fusion on Catalytic Activity of Sequence-Specific Chimeric Recombinases Determined by a Facile Fluorescent System.2012
- Author(s)
  Wataru Nomura, Akemi Masuda, Kenji Ohba, Arisa Urabe, Nobutoshi Ito, Akihide Ryo, Naoki Yamamoto & Hirokazu Tamamura
- Journal Title
  
  Biochemistry
  
  Volume: 51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659043
[Journal Article] Development of Anti-HIV Agents Based on Chemical Biology2012
- Author(s)
  玉村啓和
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132 Issue: 1 Pages: 69-78
- DOI
  10.1248/yakushi.132.69
- NAID
  130001871964
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2012-01-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021
[Journal Article] Synthetic C34Trimer of HIV-1 gp41 Shows Significant Increase of Inhibition Potency2012
- Author(s)
  Nomura W, Yamamoto N, Tamamura H(他8人、11番目)
- Journal Title
  
  Chem Med Chem
  
  Volume: 7巻 Pages: 205-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] ケミカルバイオロジーを基盤とした抗HIV剤の創製2012
- Author(s)
  玉村啓和(他0人、1番目)
- Journal Title
  
  薬学雑誌(日本薬学会)
  
  Volume: 31(1)巻 Pages: 69-78
- NAID
  130001871964
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Effects of DNABinding of Zinc Finger and Linkers for Domain Fusion on Catalytic Activity of Sequence-Specific Chimeric Recombinases Determined by a Facile Fluorescent System2012
- Author(s)
  Nomura W, Yamamoto N, Tamamura H(他5人、8番目)
- Journal Title
  
  Fluorescent System
  
  Pages: 1510-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Conjugation of Cell-penetrating Peptides Leads to Identification of Anti-HIV Peptides from Matrix Proteins2012
- Author(s)
  Narumi T, Nomura W, Tamamura H, 他8人、11番目
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 20巻 Pages: 1468-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Conjugation of Cell-penetrating Peptides Leads to Identification of Anti-HIV Peptidesfrom Matrix Proteins2012
- Author(s)
  Narumi T, Nomura W, Tamamura H(他8人、11番目)
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 20巻 Pages: 1468-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase of Inhibition Potency2012
- Author(s)
  Nomura W, Yamamoto N, Tamamura H, 他8人、11番目
- Journal Title
  
  Chem Med Chem
  
  Volume: 7巻 Pages: 205-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] ケミカルバイオロジーを基盤とした抗HIV剤の創製2012
- Author(s)
  玉村啓和, 他0人、1番目
- Journal Title
  
  薬学雑誌(日本薬学会)
  
  Volume: 131(1)巻 Pages: 69-78
- NAID
  130001871964
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Fluorescence-Quenching Screening of Protein Kinase C Ligands withan Environmentally Sensitive Fluorophore2011
- Author(s)
  Nomura W, Ikura T, Ito N, Tamamura H
- Journal Title
  
  Bioconjugate Chem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] The Success and Failures of HIV Drug Discovery2011
- Author(s)
  C.Hashimoto, T.Tanaka, et.al.
- Journal Title
  
  Expert Opinion in Drug Discovery
  
  Volume: 6 Issue: 10 Pages: 1067-1090
- DOI
  10.1517/17460441.2011.611129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05336, KAKENHI-PROJECT-11J05127, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-23710251
[Journal Article] Small Molecular CD4 Mimics as HIV Entry Inhibitors2011
- Author(s)
  Narumi T, Nomura W, Matsushita S, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 19 Issue: 22 Pages: 6735-6742
- DOI
  10.1016/j.bmc.2011.09.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-22790163, KAKENHI-PROJECT-23710251
[Journal Article] Azamacrocyclic-metal Complexes as CXCR4 Antagonists2011
- Author(s)
  T. Tanaka, W. Nomura, N. Yamamoto, H. Tamamura, 他7人、11番目
- Journal Title
  
  Chem Med Chem
  
  Volume: 6巻 Pages: 834-839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Small Molecular CD4 Mimics as HIV Entry Inhibitors2011
- Author(s)
  T. Narumi, W. Nomura, H. Tamamura, 他4人、7番目
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 19巻 Pages: 6735-6742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Intense Blue Fluorescence in a Leucine Zipper Assembly2011
- Author(s)
  H. Tsutsumi, W. Nomura, H. Tamamura, 他2人、5番目
- Journal Title
  
  Chem Bio Chem
  
  Volume: 12巻 Pages: 691-694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] The Success and Failures of HIV Drug Discovery2011
- Author(s)
  C. Hashimoto, W. Nomura, H. Tamamura, 他2人、5番目
- Journal Title
  
  Expert Opin. Drug Discovery
  
  Volume: 6巻 Pages: 1067-1090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] The Successand Failures of HIV Drug Discovery2011
- Author(s)
  C. Hashimoto, W. Nomura, H. Tamamura(他2人、5番目)
- Journal Title
  
  Expert Opin. Drug Discovery
  
  Volume: 6巻 Pages: 1067-1090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Intense blue fluorescence in a leucine zipper assembly2011
- Author(s)
  Tsutsumi H, Abe S, Mino T, Nomura W, Tamamura H
- Journal Title
  
  ChemBioChem
  
  Volume: 12 Issue: 5 Pages: 691-694
- DOI
  10.1002/cbic.201000692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021
[Journal Article] Synthetic Caged DAG-lactones for Photochemically-controlled Activation of Protein Kinase C2011
- Author(s)
  Nomura, Wataru
- Journal Title
  
  ChemBioChem
  
  Volume: VOL.12 Issue: 4 Pages: 535-539
- DOI
  10.1002/cbic.201000670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02617, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22310141, KAKENHI-PROJECT-22659021
[Journal Article] HIV-1 gp120 Enhances Outward Potassium Current via CXCR4 and cAMP-Dependent Protein Kinase a Signaling in Cultured Rat Microglia2011
- Author(s)
  Xu C, Liu J, Chen L, Liang S, Fujii N, Tamamura H, Xiong H
- Journal Title
  
  Glia
  
  Volume: 59 Issue: 6 Pages: 997-1007
- DOI
  10.1002/glia.21171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021
[Journal Article] Fluorescent-responsive Synthetic C1b Domains of ProteinKinase Cδas Reporters of Specific High Affinity Ligand Binding2011
- Author(s)
  N. Ohashi, W. Nomura, H. Tamamura(他4人、7番目)
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 22巻 Pages: 82-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] The Increase in Surface CXCR4 Expression on Lung Extravascular Neutrophils and its Effects on Neutrophils During Endotoxin-Induced Lung Injury2011
- Author(s)
  Yamada M, Kitagawa M, Yano H, Tamamura H, Fujii N, Kaku M, et al.
- Journal Title
  
  Cell Mol Immunol
  
  Volume: 8 Issue: 4 Pages: 305-314
- DOI
  10.1038/cmi.2011.8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-22790745
[Journal Article] Azamacrocyclic-metal Complexes as CXCR4 Antagonists2011
- Author(s)
  T. Tanaka, W. Nomura, N. Yamamoto, H. Tamamura(他7人、11番目)
- Journal Title
  
  Chem Med Chem
  
  Volume: 6巻 Pages: 834-839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Azamacrocyclic-metal Complexes as CXCR4 Antagonists2011
- Author(s)
  T.Tanaka, et.al.
- Journal Title
  
  ChemMedChem
  
  Volume: 6 Issue: 5 Pages: 834-839
- DOI
  10.1002/cmdc.201000548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05336, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-23710251
[Journal Article] Synthetic Caged DAG-lactones for Photochemically-controlled Activation of Protein Kinase C2011
- Author(s)
  Nomura W, Lewin NE, Blumberg PM, Furuta T, Tamamura H, et al.
- Journal Title
  
  ChemBioChem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Fluorescent-responsive Synthetic Clb Domains of Protein Kinase Cδ as Reporters of Specific High Affinity Ligand Binding2011
- Author(s)
  Ohashi N, Nomura W, Tamamura H, et al.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 22 Pages: 82-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Azamacrocyclic-metal Complexes as CXCR4 Antagonists2011
- Author(s)
  Tanaka T, Nomura W, Murakami T, Yamamoto N, Tamamura H, et al.
- Journal Title
  
  ChemMedChem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Synthetic Caged DAG-lactones for Photochemically-controlled Activation of Protein Kinase C2011
- Author(s)
  W. Nomura, T. H. Tamamura, 他6人、8番目
- Journal Title
  
  Chem Bio Chem
  
  Volume: 12巻 Pages: 535-539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Intense Blue Fluorescence in a Leucine Zipper Assembly2011
- Author(s)
  H. Tsutsumi, W. Nomura, H. Tamamura(他2人、5番目)
- Journal Title
  
  Chem Bio Chem
  
  Volume: 12巻 Pages: 691-694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Synthetic Caged DAG-lactones for Photochemically-controlled Activation of Protein Kinase C2011
- Author(s)
  W. Nomura, T. H. Tamamura(他6人、8番目)
- Journal Title
  
  Chem Bio Chem
  
  Volume: 12巻 Pages: 535-539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Fluorescence-Quenching Screening of Protein Kinase C Ligands with an Environ mentally Sensitive Fluorophore2011
- Author(s)
  Nomura, Wataru
- Journal Title
  
  Bioconjugate Chem
  
  Volume: VOL.22 Issue: 5 Pages: 923-930
- DOI
  10.1021/bc100567k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02617, KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021, KAKENHI-PROJECT-23710251
[Journal Article] Small Molecular CD4Mimics as HIV Entry Inhibitors2011
- Author(s)
  T. Narumi, W. Nomura, H. Tamamura(他4人、7番目)
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 19巻 Pages: 6735-6742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Fluorescent-responsive Synthetic C1b Domains of Protein Kinase Cδ as Reporters of Specific High Affinity Ligand Binding2011
- Author(s)
  Ohashi N, Nomura W, Tamamura H, et al.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 22 Issue: 1 Pages: 82-87
- DOI
  10.1021/bc100414a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029, KAKENHI-PROJECT-22659021
[Journal Article] Fluorescence-Quenching Screening of Protein Kinase C Ligands with an Environmentally Sensitive Fluorophore2011
- Author(s)
  W. Nomura, H. Tamamura, 他5人、7番目
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 22巻 Pages: 923-930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Fluorescence-Quenching Screening of Protein Kinase C Ligands with an Environmentally Sensitive Fluorophore2011
- Author(s)
  W. Nomura, H. Tamamura(他5人、7番目)
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 22巻 Pages: 923-930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Fluorescent-responsive Synthetic C1b Domains of Protein Kinase Cδas Reporters of Specific High Affinity Ligand Binding2011
- Author(s)
  N. Ohashi, W. Nomura, H. Tamamura, 他4人、7番目
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 22巻 Pages: 82-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Peptidic HIV integrase inhibitors derived from HIV gene products: Structure-activity relationship studies2011
- Author(s)
  Suzuki S, Yamamoto N, Pommier Y, Nomura W, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 18 Pages: 6771-6775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Azamacrocyclic-metal Complexes as CXCR4 Antagonists2011
- Author(s)
  Tanaka T, Nomura W, Murakami T, Yamamoto N , Tamamura H, et al.
- Journal Title
  
  ChemMedChem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Induction of myogenic differentiation by SDF-1 via CXCR4 andCXCR7 receptors2010
- Author(s)
  Melchionna R, Carlo AD, Fujii N, Tamamura H, Napolitano CM, Germani A, et al.
- Journal Title
  
  Muscle Nerve
  
  Volume: 41(6) Pages: 828-835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Peptide HIV-1 integrase inhibitors from HIV-1 gene products2010
- Author(s)
  Suzuki S, Yamamoto N, Tamamura H, et al.
- Journal Title
  
  J Med Chem
  
  Volume: 53(14) Pages: 5356-5360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Peptidic HIV integrase inhibitors derived from HIV gene products : Structure-activity relationship studies2010
- Author(s)
  Suzuki S, Yamamoto N, Pommier Y, Nomura W, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 18 Pages: 6771-6775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors2010
- Author(s)
  Melchionna R, Carlo AD, Fujii N, Tamamura H, Napolitano CM, Germani A, et al.
- Journal Title
  
  Muscle Nerve
  
  Volume: 41(6) Pages: 828-835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] エピジェネティクな遺伝子発現制御のためのDNAメチル化酵素の創製2010
- Author(s)
  野村渉、玉村啓和, 他1人、3番目
- Journal Title
  
  「生化学」ミニレビュウ(日本生化学会東京)
  
  Volume: 82巻5号 Pages: 393-397
- NAID
  10026425888
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] CD4 Mimics Targetingthe Mechanism of HIV2010
- Author(s)
  Y. Yamada, W. Nomura, H. Tamamura(他7人、10番目)
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20巻 Pages: 354-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Bivalent Ligands of CXCR4 with Rigid Linkers for Elucidation of Dimerization State in Cells2010
- Author(s)
  T. Tanaka, W. Nomura, H. Tamamura, 他2人、5番目
- Journal Title
  
  J. Am. Chem. Soc.(Commun.)
  
  Volume: 132巻 Pages: 15899-15901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] ペプチドミメティックによる創薬研究2010
- Author(s)
  鳴海哲夫、玉村啓和, 他0人、2番目
- Journal Title
  
  「生化学」特集号「ペプチド科学と生化学の接点」(日本生化学会東京)
  
  Volume: 82巻6号 Pages: 515-523
- NAID
  10026900008
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Improvement of lentiviral vector-mediated gene transduction bygenetic engineering of the structural protein Pr55Gag2010
- Author(s)
  Aoki T, Tamamura H, Yamamoto N, Komano J, et al.
- Journal Title
  
  Gene Ther
  
  Volume: 17(9) Pages: 1124-1133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins2010
- Author(s)
  W. Nomura, H. Tamamura(他6人、8番目)
- Journal Title
  
  Biopolymers
  
  Volume: 94巻 Pages: 843-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] CD4 Mimics Targeting the Mechanism of HIV2010
- Author(s)
  Y. Yamada, W. Nomura, H. Tamamura, 他7人、10番目
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20巻 Pages: 354-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] ペプチドミメティックによる創薬研究2010
- Author(s)
  鳴海哲夫、玉村啓和(他0人、2番目)
- Journal Title
  
  生化学特集号
  
  Volume: 82巻6号 Pages: 515-523
- NAID
  10026900008
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist2010
- Author(s)
  Narumi T, Nomura W, Matsushita S, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 20 Pages: 5853-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist2010
- Author(s)
  Narumi T, Nomura W, Matsushita S, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 20 Pages: 5853-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] CD4 mimics targeting the mechanism of HIV2010
- Author(s)
  Yamada Y, Nomura W, Matsushita S, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 20 Pages: 354-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products : Structure-Activity Relationship Studies2010
- Author(s)
  S. Suzuki, W. Nomura, N. Yamamoto, H. Tamamura, 他11人、15番目
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 18巻 Pages: 6771-6775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Enhanced exposure of human immunodeficiency virus type 1 primary isolate neutralization epitopes through binding of CD4 mimetic compounds2010
- Author(s)
  Yoshimura K, Tamamura H, Matsushita S, et al.
- Journal Title
  
  J Virol
  
  Volume: 84(15) Pages: 7558-7568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Peptide HIV-1 integrase inhibitors from HIV-1 gene products2010
- Author(s)
  Suzuki S, Yamamoto N, Tamamura H, et al.
- Journal Title
  
  J Med Chem
  
  Volume: 53(14) Pages: 5356-5360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Remodeling of Dynamic Structures of HIV-1 Envelope Proteins Leads to Synthetic Antigen Molecules Inducing Neutralizing Antibodies2010
- Author(s)
  T. Nakahara, W. Nomura, T. Narumi, N. Yamamoto, H. Tamamura(他5人、10番目)
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 21(4)巻 Pages: 709-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] エピジェネティクな遺伝子発現制御のためのDNAメチル化酵素の創製2010
- Author(s)
  野村渉、玉村啓和(他1人、3番目)
- Journal Title
  
  生化学ミニレビュウ
  
  Volume: 82巻5号 Pages: 393-397
- NAID
  10026425888
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Improvement of lentiviral vector-mediated gene transduction by genetic engineering of the structural protein Pr55Gag2010
- Author(s)
  Aoki T, Tamamura H, Yamamoto N, Komano J, et al.
- Journal Title
  
  Gene Ther
  
  Volume: 17(9) Pages: 1124-1133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Enhanced exposure of human immunodeficiency virus type 1 primary isolate neutralization epitopes through binding of CD4 mimetic compounds2010
- Author(s)
  Yoshimura K, Tamamura H, Matsushita S, et al.
- Journal Title
  
  J Virol
  
  Volume: 84(15) Pages: 7558-7568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins2010
- Author(s)
  W. Nomura, H. Tamamura, 他6人、8番目
- Journal Title
  
  Biopolymers
  
  Volume: 94巻 Pages: 843-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Remodeling of Dynamic Structures of HIV-1 Envelope Proteins Leads to Synthetic Antigen Molecules Inducing Neutralizing Antibodies2010
- Author(s)
  T. Nakahara, W. Nomura, T. Narumi, N. Yamamoto, H. Tamamura, 他5人、10番目
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 21(4)巻 Pages: 709-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products : Structure-Activity Relationship Studies2010
- Author(s)
  S. Suzuki, W. Nomura, N. Yamamoto, H. Tamamura(他11人、15番目)
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 18巻 Pages: 6771-6775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Bivalent ligands of CXCR4 with rigid linkers for elucidation of dimerization state in cells2010
- Author(s)
  Tanaka T, Nomura W, Narumi T, Masuda A, Tamamura H
- Journal Title
  
  J Am Chem Soc
  
  Volume: 132(45) Pages: 15899-15901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] CD4Mimics Targeting the HIV Entry Mechanism and their Hybrid Moleculeswith a CXCR4 Antagonist2010
- Author(s)
  T. Narumi, W. Nomura, H. Arai, T. Ozaki, N. Ohashi, S. Matsushita, H. Tamamura(他4人、11番目)
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20巻 Pages: 5853-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Bivalent ligands of CXCR4 with rigid linkers for elucidation of dimerization state in cells2010
- Author(s)
  Tanaka T, Nomura W, Narumi T, Masuda A, Tamamura H
- Journal Title
  
  J Am Chem Soc
  
  Volume: 132(45) Pages: 15899-15901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] CD4 Mimics Targeting the HIV Entry Mechanism and their Hybrid Molecules with a CXCR4 Antagonist2010
- Author(s)
  T. Narumi, W. Nomura, H. Arai, T. Ozaki, N. Ohashi, S. Matsushita, H. Tamamura, 他4人、11番目
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 20巻 Pages: 5853-5858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins2010
- Author(s)
  Nomura W, Tsutsumi H, Tamamura H, et al.
- Journal Title
  
  Biopolymers : Peptide Science
  
  Volume: 94 Pages: 843-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies2010
- Author(s)
  Nakahara T, Nomura W, Yamamoto N, Tamamura H, et al.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 21(4) Pages: 709-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Development of Crosslink-Type Tag-Probe Pairs for Fluorescent Imaging of Proteins2010
- Author(s)
  Nomura W, Tsutsumi H, Tamamura H, et al.
- Journal Title
  
  Biopolymers : Peptide Science
  
  Volume: 94 Pages: 843-852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies2010
- Author(s)
  Nakahara T, Nomura W, Yamamoto N, Tamamura H, et al.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 21(4) Pages: 709-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] CD4 mimics targeting the mechanism of HIV2010
- Author(s)
  Yamada Y, Nomura W, Matsushita S, Tamamura H, et al.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 20 Pages: 354-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] CD4 Mimics Targeting the Mechanism of HIV2010
- Author(s)
  Yamada Y, Nomura W, Tamamura H, et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 20
  
  Pages: 354-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products2010
- Author(s)
  S. Suzuki, E. W. Nomura, H. Tamamura, 他19人、22番目
- Journal Title
  
  J. Med. Chem
  
  Volume: 53(14)巻 Pages: 5356-5360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products2010
- Author(s)
  S. Suzuki, E. W. Nomura, H. Tamamura(他19人、22番目)
- Journal Title
  
  J. Med. Chem
  
  Volume: 53(14)巻 Pages: 5356-5360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Structure-Activity Relationship Study on Artificial CXCR4 Ligands Possessing the Cyclic Pentapeptide Scaffold : the Exploration of AminoAcid Residues of Pentapeptides by Substitutions of Several Aromatic Amino Acids2009
- Author(s)
  T. Tanaka, W. Nomura, H. Tamamura(他9人、12番目)
- Journal Title
  
  Org. Biomol. Chem
  
  Volume: 7巻 Pages: 3805-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] A NewClass of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor2009
- Author(s)
  Y. Inaba, N. H. Tamamura, K. Yamamoto(他6人、6番目)
- Journal Title
  
  J. Med. Chem
  
  Volume: 52(5)巻 Pages: 1438-1449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article]2009
- Author(s)
  玉村啓和
- Journal Title
  
  日本エイズ学会誌11巻、2号(日本エイズ学会)
  
  Pages: 100-101
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus.2009
- Author(s)
  F. Mizukoshi, H. Tamamura, et al
- Journal Title
  
  J. Vet. Med, Sci. 71(1)
  
  Pages: 121-124
- NAID
  110007055389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Structure-Activity Relationship Study on Artificial CXCR4 Ligands Possessing the Cyclic Pentapeptide Scaffold : the Exploration of Amino Acid Residues of Pentapeptides by Substitutions of Several Aromatic Amino Acids2009
- Author(s)
  T. Tanaka, W. Nomura, H. Tamamura, 他9人、12番目
- Journal Title
  
  Org. Biomol. Chem
  
  Volume: 7巻 Pages: 3805-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Synthesis of protein kinase Cδ C1b domain by native chemical ligation methodology and characterization of its folding and ligand binding2009
- Author(s)
  Ohashi N, Nomura W, Tamamura H, et al.
- Journal Title
  
  J.Pept.Sci. 15(10)
  
  Pages: 642-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Fluorogenically Active Leucine Zipper Peptides as New Tag-Probe Pairs for Protein Imaging in Living Cells2009
- Author(s)
  H. Tsutsumi, W. Nomura, H. Tamamura, 他8人、11番目
- Journal Title
  
  Angew. Chem., Int. Ed.
  
  Volume: 48巻 Pages: 9164-9166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] 種々の作用点をターゲットとした抗HIV剤の創製2009
- Author(s)
  玉村啓和, 他0人、1番目
- Journal Title
  
  日本エイズ学会誌
  
  Volume: 11巻2号 Pages: 100-101
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Synthesis of Protein Kinase CδC1b Domain by Native Chemical Ligation Methodologyand Characterization of its Folding andLigand Binding2009
- Author(s)
  N. Ohashi, W. Nomura, H. Tamamura(他4人、7番目)
- Journal Title
  
  J. Pept. Sci
  
  Volume: 15(10)巻 Pages: 642-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] 種々の作用点をターゲットとした抗HIV剤の創製2009
- Author(s)
  玉村啓和(他0人、1番目)
- Journal Title
  
  日本エイズ学会誌
  
  Volume: 11巻2号 Pages: 100-101
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Fluorogenically Active Leucine Zipper Peptides as New Tag-Probe Pairs for Protein Imaging in Living Cells2009
- Author(s)
  H. Tsutsumi, W. Nomura, H. Tamamura(他8人、11番目)
- Journal Title
  
  Angew. Chem., Int. Ed
  
  Volume: 48巻 Pages: 9164-9166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659021
[Journal Article] Synthesis of Protein Kinase CδC1b Domain by Native Chemical Ligation Methodology and Characterization of its Folding and Ligand Binding2009
- Author(s)
  N. Ohashi, W. Nomura, H. Tamamura, 他4人、7番目
- Journal Title
  
  J. Pept. Sci
  
  Volume: 15(10)巻 Pages: 642-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor2009
- Author(s)
  Inaba Y, Tamamura H, Yamamoto K, et al.
- Journal Title
  
  J.Med.Chem. 52(5)
  
  Pages: 1438-1449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold : the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids2009
- Author(s)
  Tanaka T, Nomura W, Tamamura H, et al.
- Journal Title
  
  Org.Biomol.Chem. 7
  
  Pages: 3805-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus2009
- Author(s)
  Mizukoshi F, Tamamura H, Fujii N, Tsujimoto H, et al.
- Journal Title
  
  J.Vet.Med.Sci. 71(1)
  
  Pages: 121-124
- NAID
  110007055389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus2009
- Author(s)
  H. Mizukoshi. H. Tamamura, (他8人、7番目)
- Journal Title
  
  J.Vet.Med.Sci 71(1)巻
  
  Pages: 121-124
- NAID
  110007055389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Fluorogenically Active Leucine Zipper Peptides as New Tag-Probe Pairs for Protein Imaging in Living Cells2009
- Author(s)
  Tsutsumi H, Nomura W, Tamamura H, et al.
- Journal Title
  
  Angew.Chem., Int.Ed. 48
  
  Pages: 9164-9166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390029
[Journal Article] A Future Perspective on the Development of Chemokine Receptor CXCR4 Antagonists2008
- Author(s)
  H. Tamamura, H. Tsutsumi, W. Nomura, T. Tanaka , N. Fujii(他0人、2番目)
- Journal Title
  
  Expert Opin. Drug Discovery 3(10)巻
  
  Pages: 1155-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists toward Downsizing2008
- Author(s)
  H. Tamamura, et al.
- Journal Title
  
  Perspectives in Medicinal Chemistry 2
  
  Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening.2008
- Author(s)
  W. Nomura, H. Tamamura, et al.
- Journal Title
  
  Bioconjugate Chem. 19
  
  Pages: 1917-1920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Modulation of Network-driven, GABA-mediated Giant Depolarizing Potentials by SDF-1 in Developing Hippocampus2008
- Author(s)
  A. Kasiyanov, N. Fujii, H. Tamamura, H.Xiong,(他0人、3番目)
- Journal Title
  
  Developmental Neuroscience 34(4)
  
  Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Potent Synergistic Anti-Human Immunodeficiency Virus (HIV) Effects Using Combinations of the CCR5 Inhibitor Aplaviroc with Other Anti-HIV Drugs.2008
- Author(s)
  H. Nakata, H. Tamamura, et al.
- Journal Title
  
  Antimicrob. Agents Chemother. 52(6)
  
  Pages: 2111-2119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Modulation of Network-driven, GABA-mediated Giant Depolarizing Potentials by SDF-1 in Developing Hippocampus.2008
- Author(s)
  A. Kasiyanov, N. Fujii, H. Tamamura & H. Xiong.
- Journal Title
  
  Developmental Neuroscience 30(4)
  
  Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of Peptide-targeted Lipoplexes to CXCR4-expressing Rat Glioma Cells and Rat Proliferating Endothelial Cells2008
- Author(s)
  W.H.P. Driessen, N. Fujii, H. Tamamura, S. M. Sullivan(他0人、3番目)
- Journal Title
  
  Mol.Ther 16(3)巻
  
  Pages: 516-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] A Future Perspective on the Development of Chemokine ReceptorCXC R4 Antagonists2008
- Author(s)
  H. Tamamura, et al.
- Journal Title
  
  Expert Opin. Drug Discovery 3(10)
  
  Pages: 1155-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening2008
- Author(s)
  W. Nomura, Y. Tanabe, H. Tsutsumi, T. Tanaka, K. Ohba, N. Yamamoto, H. Tamamura(他0人、1番目)
- Journal Title
  
  Bioconjugate Chem 19巻
  
  Pages: 1917-1920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Structure-activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold : Identification of the New Pharmacophore2008
- Author(s)
  T. Tanaka, H. Tsutsumi, W. Nomura, N. Fujii, H. Tamamura(他10人、3番目)
- Journal Title
  
  Bioconjugate Chem 6(23)
  
  Pages: 4374-4377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Potent SynergisticAnti-Human Immunodeficiency Virus(HIV)Effects Using Combinations of the CCR5 Inhibitor Aplaviroc with Other Anti-HIV Drugs2008
- Author(s)
  H. Nakatai H. Tamamura, N. Fujii, H. Mits,(他4人、6番目)
- Journal Title
  
  Antimicrob. Agents Chemother 52(6)巻
  
  Pages: 2111-2119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of Peptide-targeted Lipoplexes to CXCR4-expressing Rat Glioma Cells and Rat Proliferating Endothelial Cells.2008
- Author(s)
  W. H. P. Driessen, H. Tamamura, et al.
- Journal Title
  
  Mol. Ther. 16(3)
  
  Pages: 516-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists toward Downsizing2008
- Author(s)
  H. Tamamura, H. Tsutsumi, W. Nomura, N. Fujii(他0人、2番目)
- Journal Title
  
  Perspectives in Medicinal Chemistry 2巻
  
  Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Structure-activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold : Identification of the New Pharmacophore2008
- Author(s)
  T. Tanaka, H. Tamamura, et al.
- Journal Title
  
  Ore. Biomol. Chem. 6(23)
  
  Pages: 4374-4377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Inhibitors of the chemokine receptor CXCR4. chemotherapy of AIDS, metastatic cancer, leukemia and rheumatoid arthritis2007
- Author(s)
  Tamamura H, et. al.
- Journal Title
  
  Lett. Drug Design Discovery 4
  
  Pages: 20-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetra- and Pentapeptide-scaffolds towards the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis2007
- Author(s)
  H. Tamamura, H. Tsutsumi, H. Masuno, N. Fujii(他0人、1番目)
- Journal Title
  
  Curr. Med. Chem 14(1)巻
  
  Pages: 93-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: Disclosing the importance of side-chain and backbone functionalities2007
- Author(s)
  Tamamura H, et. al.
- Journal Title
  
  J. Med. Chem. 50(2)
  
  Pages: 192-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] CXCR4 Engagement Promotes Dendritic Cell Survival and Maturation2007
- Author(s)
  K. Kabashima, K. Sugita, N. Shiraishi, H. Tamamura, N. Fujii, Y. Tokura(他0人、4番目)
- Journal Title
  
  Biochem.Biophys.Res.Commun 361巻
  
  Pages: 1012-1016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] The Therapeutic Potential of the Chemokine Receptor CXCR4 Antagonists as Multi-functional Agents2007
- Author(s)
  H. Tsutsumi, H. Tamamura, N. Fujii(他7人、1番目)
- Journal Title
  
  Biopolymers : Peptide Science 88(2)巻
  
  Pages: 279-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] CXCL12-CXCR4 Engagement Is Required for Migration of Cutaneous Dendritic Cells2007
- Author(s)
  K. Kabashima, H. Tamamura, N.Fujii, K. Inaba, Y. Tokura(他7人、9番目)
- Journal Title
  
  Am.J Pathol 171(4)巻
  
  Pages: 1249-1257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Direct Assessment of CXCR4 Mutant Conformations Reveals Complex link between Receptor Structure and Galphai Activation2007
- Author(s)
  Y A. Berchiche, K. Y. Chow, B. Lagane, M. Leduc, Y. Percherancier, N. Fujii, H. Tamamura, F. Bachelerie, N. Heveker(他0人、7番目)
- Journal Title
  
  J.Biol.Chem.Commun. 282巻
  
  Pages: 5111-5115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Rapid Hematopoietic Progenitor Mobilization by Sulfated Colominic Acid2007
- Author(s)
  S. Kubonishi, T. Kikuchi, S. Yamaguchi, H. Tamamura, N. Fujii, Y. Katayama(他5人、4番目)
- Journal Title
  
  Biochem.Biophys.Res.Commun 355(4)巻
  
  Pages: 970-975
- NAID
  120001384686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra-and pentapeptide-scaffolds to wards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis2007
- Author(s)
  Tamamura H, et. al.
- Journal Title
  
  Curr. Med. Chem 14(1)
  
  Pages: 93-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Inhibitors of the Chemokine Receptor CXCR4. Chemotherapy of AIDS, Metastatic Cancer Leukemia and Rheumatoid Arthritis2007
- Author(s)
  H. Tsutsumi, H. Tamamura, N. Fujii(他0人、1番目)
- Journal Title
  
  Lett. Drug Design Discovery 4巻
  
  Pages: 20-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Structure-Activity Relationships of Cyclic Peptide-Based Chemokine Receptor CXCR4 Antagonists : Disclosing the Importance of Side-Chain and Backbone Functionalities2007
- Author(s)
  S. Ueda, S. Oishi, Z. Wang, T. Araki, H. Tamamura, N. Fujii(他6人、5番目)
- Journal Title
  
  J.Med.Chem 50(2)巻
  
  Pages: 192-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Versatile Use of Acid-catalyzed Ring-opening of β-Aziridinyl-a, 13-enoatesto Stereoselective Synthesis of Peptidomimetics2007
- Author(s)
  H. Tamamura, T. Tanaka, H. Tsutsumi, N. Fujii(他4人、3番目)
- Journal Title
  
  Tetrahedron 63巻
  
  Pages: 9243-9254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of a Linear Type of Low Molecular Weight CXCR4 Antagonists Based on T140 Analogs2006
- Author(s)
  H. Tamamura, H. Tsutsumi, H. Nakashima, N. Yamamoto, S. C. Peiper, N. Fujii(他5人、1番目)
- Journal Title
  
  Org.Biomol.Chem 4巻
  
  Pages: 2354-2357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Identification of a New Class of Low Molecular Weight Antagonists against the Chemokine Receptor CXCR4 Having the Dipicolylamine-Zinc(II)Complex Structure2006
- Author(s)
  H. Tamamura, A. Ojida, H. Tsutsumi, H.Nakashima,N. Yamamoto, I. Hamachi, N. Fujii(他2人、1番目)
- Journal Title
  
  J Med.Chem 49巻
  
  Pages: 3412-3415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Specific Probes for Chemokine Receptors2006
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Chem. Biol. 13
  
  Pages: 8-10
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] he Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases2006
- Author(s)
  H. Tamamura, H. Tsutsumi, N. Fujii(他0人、1番目)
- Journal Title
  
  Mini-Rev Med.Chem 6巻
  
  Pages: 989-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] The Involvement of Stromal Derived Factor la in Homing and Progression of Multiple Myeloma in the 5TMM Model2006
- Author(s)
  E. Menu, N. Fujii, H. Tamamura, K. Vanderkerken(他7人、9番目)
- Journal Title
  
  Haematologica/the Hematology Journal 91巻
  
  Pages: 605-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Identification of a New Class of Low Molecular Weight Antagonists agains the Chemokine Receptor CXCR4 Having the Dipicolylamine-Zinc(II) Complex Structure2006
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J. Med. Chem. 49(11)
  
  Pages: 3412-3415
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] A Radiolabeled CXCR4 Inhibitor for Tumor Imaging2006
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Nucl. Med. Biol. 33(4)
  
  Pages: 489-494
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] A Radiolabeled CXCR4 Inhibitor for Tumor Imaging2006
- Author(s)
  H. Hanaoka, H.Tamamura, N. Fujii, H. Saji(他6人、3番目)
- Journal Title
  
  Nucl.Med.Biol 33巻
  
  Pages: 489-494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] The Involvement of Storomal Derived Factor 1α in Homing and Progression of Multiple Myeloma in the 5TMM Model2006
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Haematologica/the Hematology Journal 91(5)
  
  Pages: 605-612
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] HIV-1 gp120 Enhances Giant Depolarizing Potentials via Chemokine Receptor CXCR4 in Neonatal Rat Hippocampus2006
- Author(s)
  A. Kasyanov, H. Tamamura, N. Fujii, H. Xiong(他0人、2番目)
- Journal Title
  
  Eur.J.Neuroscience 23巻
  
  Pages: 1120-1128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] The Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases2006
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Mini-Rev. Med. Chem. 6
  
  Pages: 989-995
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Specific Probes for Chemokine Receptors2006
- Author(s)
  H. Tamamura, H. Tsutsumi(他0人、1番目)
- Journal Title
  
  Chem.Biol 13巻
  
  Pages: 8-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of a Linear Type of Low Molecular Weight CXCR4 Antagonists Based on T140 Analogs2006
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Org. Biomol. Chem. 4
  
  Pages: 2354-2357
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC131.2005
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-16015266
[Journal Article] Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  J.Med.Chem. 48巻
  
  Pages: 3280-3289
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Chemokine Receptor Expression in EBV-associated Lymphoproliferation in Hu/SCID Mice : Implications for CXCL12/CXCR4 Axis in Lymphoma Generation.2005
- Author(s)
  E.Piovan, H.Tamamura, et al.
- Journal Title
  
  Blood 105
  
  Pages: 931-939
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)-alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  J. Med. Chem. 48巻
  
  Pages: 380-391
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Development of anti-HIV agents targeting dynamic supramolecular mechanism : Entry and fusion inhibitors based on CXCR4/CCR5 antagonists and gp41-C34-remodeling peptides.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  Current HIV Res. 3巻
  
  Pages: 289-301
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl) alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC1312005
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC 131.2005
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Identification of Novel Low Molecular Weight CXCR4 Antagonists by Structural Tuning of Cyclic Tetrapeptide-scaffolds.2005
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 3280-3289
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC131.2005
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Structure-activity Relationship Studies on CXCR4 Antagonists Having Cyclic Pentapeptide Scaffolds.2005
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Org.Biomol.Chem. 3
  
  Pages: 4392-4394
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  Org.Biomol.Chem. 3巻
  
  Pages: 4392-4394
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.2005
- Author(s)
  Hirokazu, Tamamura et al.
- Journal Title
  
  J Med Chem. 48
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Development of Anti-HIV Agents Targeting Dynamic Supramolecular Mechanism : Entry and Fusion Inhibitors Based on CXCR4/CCR5 Antagonists and gp41-C34-Remodeling Peptides.2005
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Curr.HIV Res. 3(4)
  
  Pages: 289-301
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  Org.Biomol.Chem 3
  
  Pages: 4392-4394
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type(E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] The Therapeutic Potential of CXCR4 Antagonists in the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis.2005
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  Expert Opin.Ther.Targets 9(6)
  
  Pages: 1267-1282
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Stereoselective Synthesis of [L-Arg, L/D-3-(2-naphthyl)alanine]-Type (E)-Alkene Dipeptide Isosteres and its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogs of the CXCR4 Antagonist FC131.2005
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 380-391
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)-alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  J.Med.Chem. 48巻
  
  Pages: 380-391
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Development of anti-HIV agents targeting dynamic supramolecular mechanism : Entry and fusion inhibitors based on CXCR4/CCR5 antagonists and gp41-C34-remodeling peptides.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  Current HIV Res. 3
  
  Pages: 289-301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  J.Med.Chem. 48
  
  Pages: 3280-3289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  J. Med. Chem. 48巻
  
  Pages: 3280-3289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds.2005
- Author(s)
  H.Tamamura
- Journal Title
  
  Org. Biomol. Chem. 3巻
  
  Pages: 4392-4394
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Two Orthogonal Approaches to Overcome Multi-Drug Resistant HIV-1s : Development of Protease Inhibitors and Entry Inhibitors Based on CXCR4 Antagonists.2004
- Author(s)
  H.Tamamura, N.Fujii
- Journal Title
  
  Curr.Drug Targets-Infectious Disorders 4(2)
  
  Pages: 103-110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Stromal Cell-Derived Factor 1-Mediated CXCR4 Signaling in Rat and Human Cortical Neural Progenitor Cells.2004
- Author(s)
  H.Peng, H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Neurosci. 76
  
  Pages: 35-50
- Data Source
  KAKENHI-PROJECT-16015266
[Journal Article] Identification of a CXCR4 Antagonist, a T140 Analog, as an Anti-rheumatoid Arthritis Agent.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  FEBS Lett. 569・1
  
  Pages: 99-104
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Two Orthogonal Approaches to Overcome Multi-Drug Resistant HIV-1s : Development of Protease Inhibitors and Entry Inhibitors Based on CXCR4 Antagonists.2004
- Author(s)
  H.Tamamura, N.Fujii
- Journal Title
  
  Curr.Drug Targets-Infectious Disorders 4・2
  
  Pages: 103-110
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Identification of a CXCR4 Antagonist, a T140 Analog, as an Anti-rheumatoid Arthritis Agent.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  FEBS Lett. 569・1
  
  Pages: 99-104
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Conformationally Constrained Analogues of Diacylglycerol. 20. The Search for an Elusive Binding Site on Protein Kinase C (PK-C) through Relocation of the Carbonyl Pharmacophore along the sn-1 Side Chain of DAG-lactones.2004
- Author(s)
  H.Tamamura, V.E.Marquez, et al.
- Journal Title
  
  J.Med.Chem. 47
  
  Pages: 644-655
- Data Source
  KAKENHI-PROJECT-16015266
[Journal Article] Identification of a CXCR4 Antagonist, a T140 Analog, as an Anti-rheumatoid Arthritis Agent.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  FEBS Lett. 569・1
  
  Pages: 99-104
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Conformationally Constrained Analogues of Diacylglycerol (DAG). 23. Hydrophobic Ligand-Protein Interactions versus Ligand-Lipid Interactions of DAG-Lactones with Protein Kinase C (PK-C).2004
- Author(s)
  H.Tamamura, V.E.Marquez, et al.
- Journal Title
  
  J.Med.Chem. 47
  
  Pages: 4858-4864
- Data Source
  KAKENHI-PROJECT-16015266
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nature Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] A Single Treatment with Microcapsules Containing a CXCR4 Antagonist Suppresses Pulmonary Metastasis of Murine Melanoma.2004
- Author(s)
  M.Takenaga, H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 320・1
  
  Pages: 226-232
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Topochemical Exploration of Potent Compounds Using Retro-enantiomer Libraries of Cyclic Pentapeptides.2004
- Author(s)
  H.Tamamura
- Journal Title
  
  Org.Biomol.Chem. 2
  
  Pages: 1255-1257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Topochemical Exploration of Potent Compounds Using Retro-Enantiomer Libraries of Cyclic Pentapeptides.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Org.Biomol.Chem. 2
  
  Pages: 1255-1257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Identification of a CXCR4 Antagonist, a T140 Analog, as an Anti-rheumatoid Arthritis Agent.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  FEBS Lett. 569・1
  
  Pages: 99-104
- Data Source
  KAKENHI-PROJECT-16015266
[Journal Article] Germinal Center Dark and Light Zone Organization Is Mediated by CXCR4 and CXCR5.2004
- Author(s)
  C.D.C.Allen, H.Tamamura, N.Fujii, J.G.Cyster, et al.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 943-952
- Data Source
  KAKENHI-PROJECT-16015266
[Journal Article] A Single Treatment with Microcapsules Containing a CXCR4 Antagonist Suppresses Pulmonary Metastasis of Murine Melanoma.2004
- Author(s)
  M.Takenaga, H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 320・1
  
  Pages: 226-232
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Stromal Cell-Derived Factor 1-Mediated CXCR4 Signaling in Rat and Human Cortical Neural Progenitor Cells.2004
- Author(s)
  H.Peng, H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Neurosci. 76
  
  Pages: 35-50
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Two Orthogonal Approaches to Overcome Multi-Drug Resistant HIV-Is : Development of Protease Inhibitors and Entry Inhibitors Based on CXCR4 Antagonists.2004
- Author(s)
  H.Tamamura, N.Fujii
- Journal Title
  
  Curr. Drug Targets-Infectious Disorders 4・2
  
  Pages: 103-110
- Data Source
  KAKENHI-PROJECT-16017250
[Journal Article] Topochemical Exploration of Potent Compounds Using Retro-Enantiomer Libraries of Cyclic Pentapeptides.2004
- Author(s)
  H.Tamamura, N.Fujii, et al.
- Journal Title
  
  Org.Biomol.Chem. 2
  
  Pages: 1255-1257
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Topochemical Exploration of Potent Compounds Using Retro-enantiomer Libraries of Cyclic Pentapeptides.2004
- Author(s)
  H.Tamamura
- Journal Title
  
  Org. Biomol. Chem. 2巻
  
  Pages: 1255-1257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Identification of a CXCR4 Antagonist, a T140 Analog, as an Anti-rheumatoid Arthritis Agent.2004
- Author(s)
  H.Tamamura
- Journal Title
  
  FEBS Lett. 569巻
  
  Pages: 99-104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Stromal Cell-Derived Factor 1-Mediated CXCR4 Signaling in Rat and Human Cortical Neural Progenitor Cells.2004
- Author(s)
  H.Peng, H.Tamamura, N.Fujii, et al.
- Journal Title
  
  J.Neurosci. 76
  
  Pages: 35-50
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] The Therapeutic Potential of CXCR4 Antagonists in the Treatment of HIV.2003
- Author(s)
  N.Fujii, H.Nakashima, H.Tamamura
- Journal Title
  
  Expert Opin.Investig.Drugs 12(2)
  
  Pages: 185-195
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Reduction of Peptide Character of HIV Protease Inhibitors that Exhibit Nanomolar Potency against Multi-drug Resistant HIV-1 Strains.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  J. Med. Chem 46巻
  
  Pages: 1764-1768
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Reduction of Peptide Character of HIV Protease Inhibitors that Exhibit Nanomolar Potency against Multi-drug Resistant HIV-1 Strains.2003
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J.Med.Chem. 46(9)
  
  Pages: 1764-1768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] Molecular-Size Reduction of a Potent CXCR4-Chemokine Antagonist Using Orthogonal Combination of Conformation- and Sequence-Based Libraries.2003
- Author(s)
  N.Fujii, H.Tamamura, et al.
- Journal Title
  
  Angew.Chem.Int.Ed. 42(28)
  
  Pages: 3251-3253
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Enhancement of the T140-based Pharmacophores Leads to the Development of More Potent and Bio-stable CXCR4 Antagonists.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  Org.Biomol.Chem. 1
  
  Pages: 3663-3669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Reduction of Peptide Character of HIV Protease Inhibitors that Exhibit Nanomolar Potency against Multi-drug Resistant HIV-1 Strains.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  J.Med.Chem. 46
  
  Pages: 1764-1768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] T140 Analogs as CXCR4 Antagonists Identified as Anti-metastatic Agents in the Treatment of Breast Cancer.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  FEBS Lett. 550巻
  
  Pages: 79-83
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Reduction of Peptide Character of HIV Protease Inhibitors that Exhibit Nanomolar Potency against Multi-drug Resistant HIV-1 Strains.2003
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J.Med.Chem. 46
  
  Pages: 1764-1768
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207099
[Journal Article] T140 Analogs as CXCR4 Antagonists Identified as Anti-metastatic Agents in the Treatment of Breast Cancer.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  FEBS Lett. 550
  
  Pages: 79-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Reduction of Peptide Character of HIV Protease Inhibitors that Exhibit Nanomolar Potency against Multi-drug Resistant HIV-1 Strains.2003
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J.Med.Chem. 46(9)
  
  Pages: 1764-1768
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Journal Article] Synthesis of Potent β-Secretase Inhibitors Containing a Hydroxyethylamine Dipeptide Isostere and Their Structure-activity Relationship Studies.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  Org.Biomol.Chew. 1
  
  Pages: 2468-2473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Synthesis of Potent CXCR4 Inhibitors Possessing Low Cytotoxicity and Improved Biostability Based on T140 Derivatives.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  Org.Biomol.Chem. 1
  
  Pages: 3656-3662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Synthesis of Potent β-Secretase Inhibitors Containing a Hydroxyethylamine Dipeptide Isostere and Their Structure-activity Relationship Studies2003
- Author(s)
  H.Tamamura
- Journal Title
  
  Org. Biomol. Chem. 1巻
  
  Pages: 2468-2473
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Synthesis of Potent CXCR4 Inhibitors Possessing Low Cytotoxicity and Improved Biostability Based on T140 Derivatives.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  Org. Biomol. Chem. 1巻
  
  Pages: 3656-3662
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Enhancement of the T140-based Pharmacophores Leads to the Development of More Potent and Bio-stable CXCR4 Antagonists.2003
- Author(s)
  H.Tamamura
- Journal Title
  
  Org. Biomol. Chem. 1巻
  
  Pages: 3663-3669
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390037
[Journal Article] Reduction of Peptide Character of HIV Protease Inhibitors that Exhibit Nanomolar Potency against Multi-drug Resistant HIV-1 Strains.2003
- Author(s)
  H.Tamamura, et al.
- Journal Title
  
  J.Med.Chem. 46
  
  Pages: 1764-1768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590099
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  東京医科歯科大学
- Filing Date
  2011-11-11
- Overseas
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-10
- Overseas
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド2011
- Inventor(s)
  玉村啓和、鳴海哲夫、野村渉、橋本知恵、駒野淳、宮内浩典
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2011-082813
- Filing Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-10
- Overseas
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2011-514322
- Filing Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド2011
- Inventor(s)
  玉村啓和、鳴海哲夫、野村渉、橋本知恵、駒野淳、宮内浩典
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2011-082813
- Filing Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2011-514322
- Filing Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド2011
- Inventor(s)
  玉村啓和、鳴海哲夫、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-11
- Overseas
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-10
- Overseas
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド2011
- Inventor(s)
  玉村啓和、鳴海哲夫、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2011-11-10
- Overseas
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2011
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  東京医科歯科大学
- Filing Date
  2011-11-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2010
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2010-05-14
- Overseas
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2010
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2010-11-25
- Overseas
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV 立体構造認識抗体誘導ペプチド抗原、及びその合成方法2010
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2010-05-14
- Acquisition Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2010
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2010-05-14
- Overseas
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] IV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2010
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2010
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2010-11-25
- Overseas
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] CXCR4多量体を認識する多価型CXCR4リガンド、及びその合成方法2009
- Inventor(s)
  玉村啓和、野村渉、鳴海哲夫
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2009-07-06
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2009
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法2009
- Inventor(s)
  玉村啓和, 中原徹, 野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2009-120352
- Filing Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] CXCR4多量体を認識する多価型CXCR4リガンド、及びその合成方法2009
- Inventor(s)
  玉村啓和、野村渉、鳴海哲夫
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2009-07-06
- Data Source
  KAKENHI-PROJECT-22659021
[Patent] HIV立体構造認識抗体誘導ペプチド抗原、及びその合成方法:番号:2009
- Inventor(s)
  玉村啓和、中原徹、野村渉
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-21390029
[Patent] 標的物質の検出方法、並びに、これに用いるタグ、DNA、ベクター、プローブ及び検出キット2008
- Inventor(s)
  玉村啓和、堤浩
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2008-03-24
- Overseas
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] Exploration of novel class anti-HIV-1 agents derived from a viral capsid protein2022
- Author(s)
  K. Tsuji; R. Wang; K. B.-A. Owusu; T. Kobayakawa; T. Murakami; H. Tamamura
- Organizer
  The 12th International Peptide Symposium/The 36th European Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03362
[Presentation] Development of HIV-1 fusion inhibitors based on dimeric derivatives of the C34 peptide and its peptidomimetics2021
- Author(s)
  Tamamura H, Kobayakawa T, Ebihara K, Murakami T, Tsuji K
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03362
[Presentation] A FRET-BASED ASSAY SYSTEM FOR PROTEIN KINASE C LIGAND SCREENING USING 1,2-DIACYLGLYCEROL-LACTONE DERIVATIVE2021
- Author(s)
  Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nami Ohashi, Wataru Nomura, Hirokazu Tamamura
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-20H03362
[Presentation] Bivalent Ligands of GPCR as Molecular Measures, Bioprobes for Cancer Cells and Anti-cancer Agents2021
- Author(s)
  Tamamura H
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03362
[Presentation] HIV感染症の根治へ向けたプロテインキナーゼC活性化剤の創製2020
- Author(s)
  42.石井貴大, 小早川拓也, 松田幸樹, 吉村和久, 辻耕平, 満屋裕明, 前田賢次, 玉村啓和
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22488
[Presentation] HIV再活性化に伴うアポトーシス誘導能を用いたHIVリザーバー除去に資する新たな Shock & Kill療法の可能性2019
- Author(s)
  松田幸樹, 服部真一朗, 土屋亮人, 小早川拓也, 潟永博之, 吉村和久, 岡慎一, 遠藤泰之, 玉村啓和, 満屋裕明, 前田賢次
- Organizer
  第33回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K22488
[Presentation] 二量体化HIV-1膜融合阻害薬の作用機構2019
- Author(s)
  村上　努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和
- Organizer
  第33回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] HIVリザーバー細胞を標的とする新規治療法開発に向けた研究2019
- Author(s)
  前田賢次, 松田幸樹, Mohammad Saiful Islam, 服部真一朗, 土屋亮人, 潟永博之, 玉村啓和, 吉村和久, 岡慎一, 満屋裕明, 佐藤賢文
- Organizer
  第29回抗ウイルス療法学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22488
[Presentation] 二量体化HIV-1膜融合阻害剤の作用機序2019
- Author(s)
  村上　努、海老原健人、小早川拓也、藤野真之、児玉栄一、玉村啓和
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] HIV潜伏感染再活性化を介してリザーバー細胞にアポトーシスを誘導するPKC活性化剤の同定2019
- Author(s)
  松田幸樹, 小早川拓也, 土屋亮人, 服部真一朗, 潟永博之, 吉村和久, 岡慎一, 遠藤泰之, 玉村啓和, 満屋裕明, 前田賢次
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22488
[Presentation] Biological and molecular characterization of a novel anti-HIV-1 compound created by in silico design and de novo organic synthesis.2018
- Author(s)
  Murakami T, Fujino M, Yokoyama M, Kobayakawa T, Takeuchi H, Masuda T, Kotani O, Tamamura H, Sato H.
- Organizer
  Cold Spring Harbor Laboratory 43rd annual meeting on Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] 二量体化に基づいた新規膜融合阻害剤の創出.2018
- Author(s)
  村上　努、海老原健人、藤野真之、本田柚子奈、小早川拓也、野村　渉、玉村啓和.
- Organizer
  第32回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Development of new membrane fusion inhibitors against HIV-1 by dimerization strategy.2018
- Author(s)
  Murakami T, Ebihara K, Fujino M, Honda Y, Kobayakawa T, Nomura W, Tamamura H. Development of new membrane fusion inhibitors against HIV-1 by dimerization strategy.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07158
[Presentation] Development of Synthetic Methods for Chloroalkene Dipeptide Isosteres and Their Applications2017
- Author(s)
  Kobayakawa T, Tamamura H
- Organizer
  The 25th American Peptide Symposium and the 9th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Rigid bivalent ligands of the chemokine receptor CXCR4 and their anti-cancer metastasis activity2017
- Author(s)
  Tamamura H
- Organizer
  KCS Biochemistry Division Summer Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] CD4 Mimics for Enhancement of Activity of HIV Neutralizing Antibodies2017
- Author(s)
  Ohashi N, Harada S, Irahara Y, Ishida Y, Konno K, Kobayakawa T, Nomura W, Matsushita S, Yoshimura K, Tamamura H
- Organizer
  The 11th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Synthesis of chloroalkene dipeptide isosteres as peptidomimetics and their biological application2017
- Author(s)
  Tamamura H
- Organizer
  12th Australian Peptide Conference 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Bivalent Ligands of the Chemokine Receptor CXCR4 with Polyproline Linkers and Their Anti-chemotactic Activity2017
- Author(s)
  Nomura W, Tanaka T, Aoki T, Tamamura H
- Organizer
  The 25th American Peptide Symposium and the 9th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Bivalent Ligands of the Chemokine Receptor CXCR4 with Polyproline Linkers and Their Anti-chemotactic Activity2017
- Author(s)
  Nomura W, Tanaka T, Aoki T, Tamamura H
- Organizer
  The 25th American Peptide Symposium and the 9th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15139
[Presentation] Rigid bivalent ligands of the chemokine receptor CXCR4 and their anti-cancer metastasis activity2017
- Author(s)
  Tamamura H
- Organizer
  KCS Biochemistry Division Summer Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15139
[Presentation] HIV外被タンパク質gp41由来ペプチドC34の二量体を基盤とした膜融合阻害剤2016
- Author(s)
  玉村啓和
- Organizer
  日本薬学会第136年会シンポジウム「抗ウイルス感染症のフロンティア」
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] Studies on new intracellular delivery peptides based on the dimerization arm sequence of the EGF receptor2016
- Author(s)
  Kei Toyama, Takaaki Mizuguchi, Yusuke Ishida, Wataru Nomura, and Hirokazu Tamamura
- Organizer
  The 8th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  Center for Learning and Innovation Takeda Pharmaceutical Company, Ltd.
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] Studies on cyclic peptides for the development of potent dimerization inhibitors against the EGF receptor2016
- Author(s)
  Takaaki Mizuguchi, Kei Toyama, Wataru Nomura, Kenichi Akaji, Hirokazu Tamamura
- Organizer
  The 8th Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  Center for Learning and Innovation Takeda Pharmaceutical Company, Ltd.
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] HIV外被タンパク質gp41由来ペプチドC34の二量体を基盤とした膜融合阻害剤2016
- Author(s)
  玉村啓和
- Organizer
  日本薬学会第136年会シンポジウム「抗ウイルス感染症のフロンティア」
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] EGF受容体の二量体化アームを基盤とした新規細胞内輸送ペプチドに関する研究2016
- Author(s)
  外山桂、水口貴章、野村渉、玉村啓和
- Organizer
  日本薬学会第136回年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] ペプチドを基盤とした中分子創薬研究－抗HIV剤の創製2015
- Author(s)
  玉村啓和
- Organizer
  第21回ペプチドフォーラム
- Place of Presentation
  東京薬科大学サテライトキャンパス、東京都千代田区
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Multivalent ligands for CXCR4 with polyproline linkers showing specific recognition for its expression2015
- Author(s)
  玉村啓和
- Organizer
  The 7th International Peptide Symposium
- Place of Presentation
  Singapore, Singapore
- Year and Date
  2015-12-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Development of peptide-lead anti-HIV agents and chemical biology2015
- Author(s)
  玉村啓和
- Organizer
  Seminar Series in University of Nebraska Medical Center
- Place of Presentation
  Omaha, USA
- Year and Date
  2015-10-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] ペプチドを基盤とした中分子創薬研究－抗HIV剤の創製2015
- Author(s)
  玉村啓和
- Organizer
  第21回ペプチドフォーラム
- Place of Presentation
  東京薬科大学サテライトキャンパス、東京都千代田区
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] Studies on a Novel Delivery Peptide Derived from the Dimerization Arm of EGF Receptor2015
- Author(s)
  Kei Toyama, Takaaki Mizuguchi, Yusuke Ishida, Wataru Nomura, and Hirokazu Tamamura
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市民会館（平塚）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] HIV-1カプシドタンパク質由来ペプチドライブラリーの構築と阻害剤の創出2015
- Author(s)
  谷田部夏香、松本大地、橋本知恵、藤野真之、水口貴章、大橋南美、野村　渉、村上　努、玉村啓和
- Organizer
  第29回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Year and Date
  2015-11-29
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] Multivalent ligands showing specific recognition for CXCR4 expression2015
- Author(s)
  玉村啓和
- Organizer
  The Seventh Peptide Engineering Meeting (PEM7)
- Place of Presentation
  Pune, India
- Year and Date
  2015-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] Development of peptide-lead anti-HIV agents and chemical biology2015
- Author(s)
  玉村啓和
- Organizer
  Seminar Series in University of Nebraska Medical Center
- Place of Presentation
  Omaha, USA
- Year and Date
  2015-10-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] 蛍光プローブを用いたEGFレセプター二量体化阻害ペプチドの機能評価2015
- Author(s)
  外山桂、水口貴章、石田有佑、野村渉、玉村啓和
- Organizer
  創薬懇話会2015
- Place of Presentation
  徳島大学（鳴門）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] An anti-HIV assay method for cell-penetrating peptides using chloroquine and identification of inhibitory peptides derived from matrix proteins2015
- Author(s)
  玉村啓和
- Organizer
  The 16th Kumamoto AIDS Seminar
- Place of Presentation
  阿蘇リゾートグランヴィリオホテル、熊本県阿蘇市
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] Peptidomimetic-based Mid-size Drug Research: Anti-HIV Agents2015
- Author(s)
  玉村啓和
- Organizer
  The 10th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] Multivalent ligands showing specific recognition for CXCR4 expression2015
- Author(s)
  玉村啓和
- Organizer
  The Seventh Peptide Engineering Meeting (PEM7)
- Place of Presentation
  Pune, India
- Year and Date
  2015-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] Peptidomimetic-based Mid-size Drug Research: Anti-HIV Agents2015
- Author(s)
  玉村啓和
- Organizer
  The 10th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] An anti-HIV assay method for cell-penetrating peptides using chloroquine and identification of inhibitory peptides derived from matrix proteins2015
- Author(s)
  玉村啓和
- Organizer
  The 16th Kumamoto AIDS Seminar
- Place of Presentation
  阿蘇リゾートグランヴィリオホテル、熊本県阿蘇市
- Year and Date
  2015-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652
[Presentation] EGFレセプター二量化阻害ペプチドの蛍光標識体の合成と機能評価2015
- Author(s)
  水口貴章、外山桂、石田有佑、野村渉、玉村啓和
- Organizer
  日本ケミカルバイオロジー学会　第10回年会
- Place of Presentation
  東北大学（仙台）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] Functional Evaluation of Fluorescent-Labeled Derivatives of an Inhibitory Peptide against EGF Receptor Dimerization2015
- Author(s)
  Takaaki Mizuguchi, Kei Toyama, Yusuke Ishida, Wataru Nomura, and Hirokazu Tamamura
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市民会館（平塚）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] Multivalent ligands for CXCR4 with polyproline linkers showing specific recognition for its expression2015
- Author(s)
  玉村啓和
- Organizer
  The 7th International Peptide Symposium
- Place of Presentation
  Singapore, Singapore
- Year and Date
  2015-12-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] 上皮成長因子受容体の「二量体化アーム」を基盤とした新規抗がん薬開発に向けた環状ペプチドに関する研究2015
- Author(s)
  水口貴章、外山桂、石田有佑、野村渉、玉村啓和
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター（幕張）
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26893061
[Presentation] ケミカルバイオロジーを基盤とした抗HIV剤の創製.シンポジウム「新しい抗感染症剤研究の最前線-発見、ケミカルバイオロジーそして創薬へ2011
- Author(s)
  玉村啓和
- Organizer
  日本薬学会第131年会(中止)
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫, 吉村和久, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 新規HIV侵入阻害剤の創製研究:低分子型CD4ミミック-CXCR4アンタゴニストのハイブリッド分子の設計と合成2011
- Author(s)
  鳴海哲夫, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] SAR Study of Small Molecular CD4 Mimics Targeting the Dynamic Supramolecular Mechanism of HIV Entry and Their Hybrid Molecules with a CXCR4 Antagonist2011
- Author(s)
  Narumi T, Arai H, Nomura W, Matsushita S, Tamamura H, et al.
- Organizer
  The 12th Kumamoto AIDS Seminar・GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 2価型CXCR4リガンドの開発と受容体結合機能の解析2011
- Author(s)
  野村渉, 玉村啓和, など
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Design, Synthesis and Biological Evaluation of CD4 Mimics Targeting the Interaction with Asp368 and Val430 in Gp1202011
- Author(s)
  Arai H, Nomura W, Matsushita S, Tamamura H, et al
- Organizer
  The 12th Kumamoto AIDS Seminar・GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 低分子型CD4ミミック:HIV外被タンパク質の構造変化を促すHIV侵入阻害剤2011
- Author(s)
  鳴海哲夫, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] CXCR4-Derived Peptides Targeting AIDS Vaccines2011
- Author(s)
  Hashimoto C, Yamamoto N, Tamamura H, et al.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIVワクチンを指向したgp41の動的構造変化を模倣した抗原ペプチドの開発研究2011
- Author(s)
  野村渉, 駒野淳, 山本直樹, 玉村啓和, など
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV-1エンベロープ蛋白質を標的とした治療を評価するためのサル/ヒト免疫不全ウイルスの作製とin vitroにおける中和感受性の評価2011
- Author(s)
  大附寛幸, 三浦智行, 玉村啓和, 松下修三, 五十嵐樹彦, など
- Organizer
  第25回近畿エイズ研究会学術集会
- Place of Presentation
  京都
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫, 野村渉, 玉村啓和, 吉村和久, 松下修三, など
- Organizer
  創薬懇話会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Study of Small Molecular CD4 Mimics Targeting the Dynamic Supramolecular Mechanism of HIV Entry and Their Hybrid Molecules with a CXCR4 Antagonist2011
- Author(s)
  Narumi T, Nomura W, Tamamura H, et. al.
- Organizer
  The 12th Kumamoto AIDS Seminar・GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Design Synthesis and BiologicalEvaluation of CD4 Mimics Targetingthe Interaction with Asp368 and Val430in Gp1202011
- Author(s)
  Arai H, Narumi T, Tamamura H, et. al.
- Organizer
  The 12th Kumamoto AIDSSeminar・GCOE Joint International Symposium. Kumamoto
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  新井啓之, 鳴海哲夫, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 細胞表面におけるCXCR4二量体構造解析のための堅固なリンカーを有する二価型リガンドの開発2011
- Author(s)
  野村渉, 田中智博, 相馬晃, 鳴海哲夫, 増田朱美, 玉村啓和
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] SAR Studies of Small Molecular CD4 Mimics Targeting the HIV Entry Mechanism2011
- Author(s)
  Narumi T, Arai H, Nomura W, Matsushita S, Tamamura H, et al
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 低分子型CD4ミミック:HIV外被タンパク質の構造変化を促すHIV侵入阻害剤2011
- Author(s)
  鳴海哲夫, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp41-C34 3量体の合成とその抗HIV作用2011
- Author(s)
  橋本知恵, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Identification of Anti-HIV Peptides Derived from Matrix Proteins2011
- Author(s)
  Narumi T, Murakami T, Tamamura H, et al.
- Organizer
  ACS Meeting Fall2011
- Place of Presentation
  Denver, Colorado, USA
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1遺伝子産物由来のインテグラーゼ阻害剤2011
- Author(s)
  玉村啓和
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1第二受容体CXCR4の細胞外ドメインを基にしたエイズワクチンの開発研究2011
- Author(s)
  橋本知恵, 鳴海哲夫, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫, 新井啓之, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 蛍光ラベル化した二価結合型CXCR4リガンドの創製と応用2011
- Author(s)
  相川春夫, 玉村啓和, など
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIVタンパク質Vprを基にしたインテグラーゼ阻害剤の構造活性相関研究2011
- Author(s)
  尾崎太郎, 野村渉, 山本直樹、玉村啓和, など
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] ケミカルバイオロジーを基盤とした抗HIV剤の創製.シンポジウム「新しい抗感染症剤研究の最前線-発見、ケミカルバイオロジーそして創薬へ-.」2011
- Author(s)
  玉村啓和
- Organizer
  日本薬学会第131年会(中止)
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Synthetic Antigens for Induction of Structure-Specific Antibodies against Trimer-Form of gp412011
- Author(s)
  Nomura W, Yamamoto N, Tamamura H, et al.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Several HIV Inhibitors Targeting Entry, Fusion, Integrase and Matrix2011
- Author(s)
  Narumi T, Nomura W, Tamamura H
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIVワクチンを指向したgp41の動的構造変化を模倣した抗原ペプチドの開発研究2011
- Author(s)
  野村渉, 駒野淳, 山本直樹, 玉村啓和, など
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 二核亜鉛錯体型CXCR4アンタゴニストの構造活性相関研究.日本ケミカルバイオロジー学会2011
- Author(s)
  尾崎太郎,野村渉,玉村啓和など
- Organizer
  第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Synthetic Antigens for Induction of Structure-Specific Antibodies against Trimer-Form of gp412011
- Author(s)
  Nomura W, Yamamoto N, Tamamura H, et al.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1遺伝子産物由来のインテグラーゼ阻害剤2011
- Author(s)
  玉村啓和
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫, 吉村和久, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 2価結合型リガンドの新規デザインによるCXCR4の細胞表面における機能解析2011
- Author(s)
  野村渉, 田中智博, 増田朱美, 鳴海哲夫, 玉村啓和
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 細胞表面におけるCXCR4二量体構造解析のための堅固なリンカーを有する二価型リガンドの開発2011
- Author(s)
  野村渉, 田中智博, 相馬晃, 鳴海哲夫, 増田朱美, 玉村啓和
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 2価結合型リガンドの新規デザインによるCXCR4の細胞表面における機能解析2011
- Author(s)
  野村渉, 田中智博, 増田朱美, 鳴海哲夫, 玉村啓和
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1 Co-Receptor CXCR4-Derived Peptides Targeting AIDS Vaccines2011
- Author(s)
  Hashimoto C, Narumi T, Nomura W, Yamamoto N, Tamamura H
- Organizer
  The 9th Australian Peptide Conference
- Place of Presentation
  Hamilton Island, Queensland, Australia
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫, 新井啓之, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Design, Synthesis and Biological Evaluation of CD4 Mimics Targeting the Interaction with Asp368 and Val430 in Gp1202011
- Author(s)
  Arai H, Nomura W, Matsushita S, Tamamura H, et al.
- Organizer
  The 12th Kumamoto AIDS Seminar・GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  新井啓之,野村渉,玉村啓和など
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV-1エンベロープ蛋白質を標的とした治療を評価するためのサル/ヒト免疫不全ウイルスの作製とin vitroにおける中和感受性の評価2011
- Author(s)
  大附寛幸, 三浦智行, 玉村啓和, 松下修三, 五十嵐樹彦, など
- Organizer
  第25回近畿エイズ研究会学術集会
- Place of Presentation
  京都
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] ペプチド化学を基盤としたケミカルバイオロジー2011
- Author(s)
  玉村啓和
- Organizer
  第14回ペプチドフォーラム
- Place of Presentation
  鹿児島
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1第二受容体CXCR4の細胞外ドメインを基にしたエイズワクチンの開発研究2011
- Author(s)
  橋本知恵, 鳴海哲夫, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 新規HIV侵入阻害剤の創製研究:低分子型CD4ミミック-CXCR4アンタゴニストのハイブリッド分子の設計と合成2011
- Author(s)
  鳴海哲夫, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Development of Bivalent Ligands for CXCR4 with Rigid Linkers and Application to Detection of Cancer Cells2011
- Author(s)
  Nomura W, Tanaka T, Masuda A, Narumi T, Tamamura H
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  Southern California, USA
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 二核亜鉛錯体型CXCR4アンタゴニストの構造活性相関研究2011
- Author(s)
  尾崎太郎, 野村渉, 村上努, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] SAR Study of Small Molecular CD4 Mimics Targeting the Dynamic Supramolecular Mechanism of HIV Entry and Their Hybrid Molecules with a CXCR4 Antagonist2011
- Author(s)
  Narumi T, Arai H, Nomura W, Matsushita S, Tamamura H, et al.
- Organizer
  The 12th Kumamoto AIDS Seminar・GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] ペプチド化学を基盤としたケミカルバイオロジー2011
- Author(s)
  玉村啓和
- Organizer
  第14回ペプチドフォーラム
- Place of Presentation
  鹿児島
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] SAR Studies of Small Molecular CD4Mimics Targeting the HIV Entry Mechanism2011
- Author(s)
  Narumi T, Nomura W, Tamamura H, et. al.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Synthesis of HIV Gp41 Trimer Mimics Inducing Neutralizing Antibodies Based on Remodeling of Dynamic Structures of HIV-1 Envelope Proteins2011
- Author(s)
  Nomura W, Nakahara T, Narumi T, Yamamoto N, Tamamura T, et al
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  Southern California, USA
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV-1 Co-Receptor CXCR4-Derived Peptides Targeting AIDS Vaccines2011
- Author(s)
  Hashimoto C, Narumi T, Nomura W, Yamamoto N, Tamamura H
- Organizer
  The 9th Australian Peptide Conference
- Place of Presentation
  Hamilton Island, Queensland, Australia
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp 120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫,野村渉,玉村啓和など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp41-C34 3量体の合成とその抗HIV作用2011
- Author(s)
  橋本知恵, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV外被タンパク質gp120の構造変化を誘起する低分子CD4ミミックの構造活性相関研究2011
- Author(s)
  鳴海哲夫, 野村渉, 玉村啓和, 吉村和久, 松下修三, など
- Organizer
  創薬懇話会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 2価型CXCR4リガンドの開発と受容体結合機能の解析2011
- Author(s)
  野村渉, 玉村啓和, など
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] CXCR4二量化状態解析のための2価結合型リガンドの合成2011
- Author(s)
  相馬晃, 玉村啓和, など
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Synthesis of HIV Gp41 Trimer Mimics Inducing Neutralizing Antibodies Based on Remodeling of Dynamic Structures of HIV-1 Envelope Proteins2011
- Author(s)
  Nomura W, Nakahara T, Narumi T, Yamamoto N, Tamamura T, et al.
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  Southern California, USA
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 蛍光ラベル化した二価結合型CXCR4リガンドの創製と応用2011
- Author(s)
  相川春夫, 玉村啓和, など
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Identification of Anti-HIV Peptides Derived from Matrix Proteins2011
- Author(s)
  Narumi T, Murakami T, Tamamura H, et al
- Organizer
  ACS Meeting Fall2011
- Place of Presentation
  Denver, Colorado, USA
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] SAR Studies of Small Molecular CD4 Mimics Targeting the HIV Entry Mechanism2011
- Author(s)
  Narumi T, Arai H, Nomura W, Matsushita S, Tamamura H, et al.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Development of Bivalent Ligands for CXCR4 with Rigid Linkers and Application to Detection of Cancer Cells2011
- Author(s)
  Nomura W, Tanaka T, Masuda A, Narumi T, Tamamura H
- Organizer
  22nd American Peptide Symposium
- Place of Presentation
  Southern California, USA
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIVタンパク質Vprを基にしたインテグラーゼ阻害剤の構造活性相関研究2011
- Author(s)
  尾崎太郎,野村渉,玉村啓和など
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Several HIV Inhibitors Targeting Entry, Fusion, Integrase and Matrix2011
- Author(s)
  Narumi T, Nomura W, Tamamura H, et. al
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] CXCR4-Derived Peptides Targeting AIDS Vaccines2011
- Author(s)
  Hashimoto C, Yamamoto N, Tamamura H, et al
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 低分子型CD4ミミック: HIV外被タンパク質の構造変化を促すHIV侵入阻害剤2011
- Author(s)
  鳴海哲夫,野村渉,松下修三,玉村啓和など
- Organizer
  第25回日本エイズ学会学術集会・総会日本エイズ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 二核亜鉛錯体型CXCR4アンタゴニストの構造活性相関研究2011
- Author(s)
  尾崎太郎, 野村渉, 村上努, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第6回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] CXCR4二量化状態解析のための2価結合型リガンドの合成2011
- Author(s)
  相馬晃, 玉村啓和, など
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV 1マトリックスタンパク質を基にした新規抗HIVペプチドめ創出2010
- Author(s)
  小森谷真央, 村上努, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Anti-HIV Inhibitors and AIDS Vaccines2010
- Author(s)
  Tamamura H
- Organizer
  International Summer Program 2010
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV-1外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの構造活性相関研究2010
- Author(s)
  鳴海哲夫, 新井啓之, 落合千裕, 吉村和久, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Structure-Activity Relationships of CXCR4 Antagonists Having the Dipicolylamine/Azamacro- Cyclic-Metal Complex Structures2010
- Author(s)
  Ozaki T, Yamamoto N, Tamamura H, et al.
- Organizer
  11th KUMAMOTO AIDS Seminer-GCOEJoint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 合成抗原ペプチドによるHIV-1 gp41の三量体構造を認識する抗体の誘導2010
- Author(s)
  野村渉, 中原徹, 大矢亜紀, 山本直樹, 玉村啓和, など
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Elucidation of a Dimerization State of a Chemokine Receptor CXCR4 via Chemical Biology Approach Utilizing Novel Bivalent Lig ands with Rigid Polyproline Linkers2010
- Author(s)
  Tanaka T, Nomura W, Narumi T, Tamamura H
- Organizer
  The 13th Akabori Conference Leipzig 2010 Japanese-German Symposium on Peptide Science
- Place of Presentation
  Leipzig, Germany
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 堅固なリンカーを有する二価結合型CXCR4リガンドの開発と応用2010
- Author(s)
  田中智博, 野村渉, 鳴海哲夫, 増田朱美, 玉村啓和
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの創製2010
- Author(s)
  鳴海哲夫, 新井啓之, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV-1マトリックスタンパク質を基にした新規抗HIVペプチドの創出2010
- Author(s)
  小森谷真央, 村上努, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1遺伝子産物由来のインテグラーゼ阻害剤の創出2010
- Author(s)
  橋本知恵, 野村渉, Maddali K, Pommier Y,山本直樹, 駒野淳, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの創製2010
- Author(s)
  鳴海哲夫, 新井啓之, 落合千裕, 松下修三, 玉村啓和, など
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの構造活性相関研究2010
- Author(s)
  鳴海哲夫, 新井啓之, 落合千裕, 吉村和久, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1遺伝子産物由来のインテグラーゼ阻害剤の創出2010
- Author(s)
  橋本知恵, 野村渉, Maddali K、Pommier Y, 山本直樹, 駒野淳, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] gp120のCD4結合サイトを模倣した新規抗原分子の創製2010
- Author(s)
  尾崎太郎, 田中智博, 宮内浩典, 野村渉, 山本直樹, 駒野淳, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 二核亜鉛錯体型CXCR4アンタゴニストの構造活性相関研究2010
- Author(s)
  尾崎太郎, 田中智博, 野村渉, 村上努, 玉村啓和, など
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1マトリックスタンパク質を基にした新規抗HIVペプチドの創出2010
- Author(s)
  小森谷真央, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Development of Small CD4 Mimic Molecules that Induce Confor mational Changes in gp1202010
- Author(s)
  Arai H, Matsushita S, Tamamura H, et al.
- Organizer
  11th KUMAMOTO AIDS Seminer GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] エイズワクチンを指向した宿主受容体CXCR4由来抗原分子の創製2010
- Author(s)
  橋本知恵, 野村渉, 田中智博, 鳴海哲夫, 山本直樹, 玉村啓和, など
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] マトリックスタンパク質を基にした新規抗HIVペプチド2010
- Author(s)
  小森谷真央, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] ケミカルバイオロジーを基盤とした抗HIV剤の創製2010
- Author(s)
  玉村啓和
- Organizer
  創薬懇話会2010in蔵王、次世代を担う若手のためのメディシナルケミストリーフォーラム
- Place of Presentation
  宮城
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products2010
- Author(s)
  Tamamura H
- Organizer
  11th KUMAMOTO AIDS Seminer-GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] リバースからフォワードへケミカルゲノミクスを活用した抗HIV創製2010
- Author(s)
  田中智博, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HIV-1外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの構造活性相関研究2010
- Author(s)
  鳴海哲夫, 落合千裕, 山田裕子, 吉村和久, 玉村啓和, など
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Peptidic HIV Integrase Inhibitors Derived from HIV Gene Produ Cts2010
- Author(s)
  Tamamura H
- Organizer
  11th KUMAMOTO AIDS Seminer GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの創製2010
- Author(s)
  鳴海哲夫, 新井啓之, 野村渉, 松下修三, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 2価結合型リガンドの新規デザインによるCXCR4の細胞表面における機能解析2010
- Author(s)
  野村渉, 田中智博, 増田朱美, 鳴海哲夫, 玉村啓和
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Elucidation of a Dimerization State of a Chemokine Receptor CXCR4 via Chemical Biology Approach Utilizing Novel Bivalent Ligands with Rigid Polyproline Linkers2010
- Author(s)
  Tanaka T, Nomura W, Tamamura H, et. al
- Organizer
  The 13th Akabori Conference Leipzig 2010 : Japanese-German Symposium on Peptide Science
- Place of Presentation
  Leipzig, Germany
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] リバースからフォワードヘケミカルゲノミクスを活用した抗HIV剤の創製2010
- Author(s)
  田中智博, 山本直樹, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 二核亜鉛錯体型CXCR4アンタゴニストの構造活性相関研究2010
- Author(s)
  尾崎太郎, 田中智博, 野村渉, 村上努, 玉村啓和, など
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] マトリックスタンパク質を基にした新規抗HIVペプチド2010
- Author(s)
  小森谷真央, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 細胞膜透過性MA部分ペプチドライブラリーを用いた新規抗HIV-1ペプチドの探索と創出2010
- Author(s)
  村上努, 小森谷真央, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Anti-HIV Inhibitors and AIDS Vaccines2010
- Author(s)
  Tamamura H
- Organizer
  International Summer Program 2010
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 2価結合型リガンドの新規デザインによるCXCR4の細胞表面における機能解析2010
- Author(s)
  野村渉, 田中智博, 増田朱美, 鳴海哲夫, 玉村啓和
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] 堅固なリンカーを有する二価結合型CXCR4リガンドの開発と応用2010
- Author(s)
  田中智博, 野村渉, 鳴海哲夫, 増田朱美, 玉村啓和
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] 細胞膜透過性MA部分ペプチドライブラリーを用いた新規抗HIV-1ペプチドの探索と創出2010
- Author(s)
  村上努, 小森谷真央, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1マトリックスタンパク質を基にした新規抗HIVペプチドの創出2010
- Author(s)
  小森谷真央, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Elucidation of a Dimerization State of a Chemokine Receptor CXCR4 via Chemical Biology Approach Utilizing Novel Bivalent Ligands with Rigid Polyproline Linkers2010
- Author(s)
  Tanaka T, Nomura W, Narumi T, Tamamura H
- Organizer
  The 13th Akabori Conference Leipzig 2010 : Japanese-German Symposium on PeptideScience
- Place of Presentation
  Leipzig, Germany
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] ケミカルバイオロジーを基盤とした抗HIV剤の創製2010
- Author(s)
  玉村啓和
- Organizer
  創薬懇話会2010 in 蔵王、次世代を担う若手のためのメディシナルケミストリーフォーラム
- Place of Presentation
  宮城
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Development of Small CD4 Mimic Molecules that Induce Conformational Changes in gp1202010
- Author(s)
  Arai H, Matsushita S, Tamamura H, et al.
- Organizer
  11th KUMAMOTO AIDS Seminer-GCOEJoint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Structure-Activity Relationships of CXCR4 Antagonists Having the Dipicolylamine/Azamacro-Cyclic-Metal Complex Structures2010
- Author(s)
  Ozaki T, Yamamoto N, Tamamura H, et al.
- Organizer
  11th KUMAMOTO AIDS Seminer GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1マトリックスタンパク質を基にした新規抗HIVペプチドの創出2010
- Author(s)
  小森谷真央, 山本直樹, 玉村啓, など
- Organizer
  日本ケミカルバイオロジー学会第5回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Peptidic HIV IntegraseInhibitors Derived from HIV GeneProducts2010
- Author(s)
  Tamamura H
- Organizer
  11th KUMAMOTO AIDSSeminer・GCOE Joint International Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] HrV外被タンパク質gp120の構造変化誘起を指向した低分子CD4ミミックの創製2010
- Author(s)
  鳴海哲夫, 新井啓之, 落合千裕, 松下修三, 玉村啓和, など
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Development of a Bivalent Ligand for a Chemokine Receptor CXCR4 by Utilizing Polyproline Helix as a Linker2010
- Author(s)
  Nomura W, Tanaka T, Masuda A, Narumi T, Tamamura H
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22659021
[Presentation] Development of a Bivalent Ligand for a Chemokine Receptor CXCR4 by Utilizing Polyproline Helix as a Linker2010
- Author(s)
  Nomura W, Tanaka T, Masuda A, Narumi T, Tamamura H
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] HIV-1マトリックスタンパク質を基にした新規抗HIVペプチドの創出2010
- Author(s)
  小森谷真央, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] gp120のCD4結合サイトを模倣した新規抗原分子の創製2010
- Author(s)
  尾崎太郎, 田中智博, 宮内浩典, 野村渉, 山本直樹, 駒野淳, 玉村啓和, など
- Organizer
  第24回日本エイズ学会学術集会・総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Development of CD4 mimic small molecules targeted for dynamic supramolecular mechanism of HIV entry2009
- Author(s)
  Ochiai C, Yoshimura K, Nomura W, Tamamura H, et al.
- Organizer
  第10回熊本エイズセミナー
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] リバースからフォワードヘケミカルゲノミクスを基盤とした抗HIV剤の創製2009
- Author(s)
  田中智博, 野村渉, 玉村啓和, など
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Chemical biology approach utilizing novel bivalent ligands for GPCR CXCR4 leads to the elucidation of a dimeric structure2009
- Author(s)
  Tanaka T, Nomura W, Narumi T, Tamamura H.
- Organizer
  The 3rd Asia-Pacific International Peptide Symposium
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] ペプチドを基盤としたケミカルバイオロジーと抗HIV剤の創製2009
- Author(s)
  玉村啓和
- Organizer
  九州ペプチドフォーラム
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] ペプチドライブラリーを基にしたHIV-1インテグラーゼに対する阻害剤の創製2009
- Author(s)
  中西勇太, 野村渉, 山本直樹, 玉村啓和, など
- Organizer
  第28回メディシナルケミストリーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] ペプチドミメティクを基盤とした阻害剤と新規概念によるワクチン2009
- Author(s)
  玉村啓和, 野村渉, 山本直樹, など
- Organizer
  第82回日本生化学会大会シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Development of an artificial antigen inducing neutralizing antibodies specific to gp41 trimer2009
- Author(s)
  玉村啓和
- Organizer
  Satellite Symposium at Mt.Aso
- Place of Presentation
  熊本
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] フォワードケミカルジェネティクスを応用したHIVインテグラーゼ阻害剤2009
- Author(s)
  中西勇太, 玉村啓和, など
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390029
[Presentation] Barry Evans, Zi-xuan Wng, Stephen C peiper, 玉村智和, 新規ファルマコフォアを有するケモカインレセプターCXCR4アンタゴニストの構造活性相関研究2008
- Author(s)
  田中智博, 玉村啓和など
- Organizer
  日本ケミカルバイオロジー研究会第3回集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] 種々の作用点をターゲットした抗HIV剤の創製2008
- Author(s)
  玉村啓和
- Organizer
  第22回エイズ学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] 抗HlV剤を中心とした創薬基礎研究2008
- Author(s)
  玉村啓和
- Organizer
  日本薬学会関東支部第22回シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] 環状ペンタベンチド骨格を有するCXCR4アンタゴニストの構造活性相関研究 : 新規ファルマコフォアの固定2008
- Author(s)
  田中智博, 玉村啓和など
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] 蛍光性CXCR4特異的プローブのスクリーニング及びイメージングへの応用2008
- Author(s)
  田中智博, 玉村啓和など
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] Chemical synthesis of a PKC Clb domain by a peptide ligation method and expression of the protein in2007
- Author(s)
  N. Ohashi, H. Tamamura, et.al.
- Organizer
  coli and their application. 4th International Peptide Symposium
- Place of Presentation
  Cairns, Australia
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha, beta-enoates2007
- Author(s)
  H. Tamamura, et.al.
- Organizer
  20th American Peptide Symposium
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] HIV-1外被タンパク質gp41-CHRの二量体構造を基盤とした膜融合阻害剤の有用性
- Author(s)
  野村　渉、水口　貴章、大橋　南美、Mathieu Metifiot、藤野　真之、Yves Pommier、駒野　淳、村上　努、玉村　啓和
- Organizer
  第28回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26460566
[Presentation] “Multimerized Peptides Derived from the C-Terminal Region of HIV-1 gp41 as Fusion Inhibitors”
- Author(s)
  Nomura W, Hashimoto C, Fujino M, Murakami T, Ohashi N, Tamamura H.
- Organizer
  The 33rd European Peptide Society Symposium.
- Place of Presentation
  Sofia, Bulgaria,
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24390024
[Presentation] “Efficient Gene Disruption at hTERT Promoter Region by Simultaneous Digestion by Pairs of ZFNs or Guide RNAs of CRISPR/Cas System”
- Author(s)
  Nomura W, Masuda A, Tamamura H.
- Organizer
  The 28th Annual Symposium of the Protein Society.
- Place of Presentation
  San Diego, USA,
- Year and Date
  2014-07-27 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-24390024
[Presentation] Development of peptide-lead anti-HIV agents.
- Author(s)
  Tamamura H.
- Organizer
  The 15th Akabori Conference 2014: Japanese-German Symposium on Peptide Science,
- Place of Presentation
  Boppard, Germany
- Year and Date
  2014-09-07 – 2014-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-26670053
[Presentation] Genome Engineering Cutting-Edge Research and Applications
- Author(s)
  Nomura W, Masuda A, Tamamura H.
- Organizer
  Enhanced Gene Disruption by Simultaneous Digestion of ZFN or CRISPR/Cas System at hTERT Promoter Region. FASEB SRC
- Place of Presentation
  Nassau, Bahamas,
- Year and Date
  2014-06-22 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-26670053

1. OTAKA Akira (20201973)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
2. FUJII Nobutaka (60109014)

# of Collaborated Projects: 9 results

# of Collaborated Products: 3 results
3. NOMURA Wataru (80463909)

# of Collaborated Projects: 5 results

# of Collaborated Products: 132 results
4. Murakami Tsutomu (50336385)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
5. IBUKA Toshiro (80025692)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. Mizuguchi Takaaki (30732557)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
7. 大橋南美 (90707051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. 小早川拓也 (30801526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. 辻耕平 (50866639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
10. AOKI Kazuhiro (40272603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAGAWA Atsushi (20188890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NARUMI Testuo (50547867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. AIKAWA Haruo (70547322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAYASHI Kyozo (00029935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IIDA Akira (40202816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMAMOTO Yoshinori (60029519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HOSOTANI Ryo (00139908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YAMAMOTO Naoki (00094053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. AKAJI Kenichi (60142296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 堤浩 (70398105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
21. 増野弘幸 (80376714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 藤多哲朗 (40027024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. FUJIMOTO Masafumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANAKA Hirokazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YOSHIMURA Kazuhisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. TOYAMA Kei

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
27. 太田光煕

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 黒川勉

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 西村紀

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. FUJINO Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
31. HARADA Shigeyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. KUWATA Takeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 谷口敦彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 三浦智行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAMAMURA Hirokazu 玉村 啓和

玉村 啓和 タマムラ ヒロカズ

Research Projects

Research Products

Co-Researchers

環状ペプチド誘導体を活用した標的選択的ハイブリッド型中分子医薬品の創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

カプシド蛋白質の二量体化を標的とした新規抗HIV薬開発に向けた基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of target-selective mid-size drugs using cyclic peptide derivativesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new therapies targeting latent infection for a radical cure of HIV infectious diseases and AIDSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of highly active HIV fusion inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemical Biology Researches Using Recognition Units for GPCR DimersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of mid-size drugs based on peptidomimeticPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of HIV-1 by Gag peptides

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of anti-HIV agents targeting weak points of viral replication mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on new chemical probes development that assumed dimeric interface of the EGF receptor ectodomain a target

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of early diagnostic methods for cancer tissue and metastasis utilizing bivalent GPCR ligandsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of swich on-off type probes for detection of GPCR dimersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new anabolic peptide on bone by the identification

Principal Investigator

Project Period (FY)

TAMAMURA Hirokazu 玉村啓和

玉村啓和タマムラヒロカズ