Masuda Takao 増田貴夫

… Alternative Names

増田貴夫マスダタカオ

MASUDA Takao 増田貴夫

Less

Researcher Number	80219336
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2022: 東京医科歯科大学, 医学部, 准教授 2020 – 2021: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2016: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2007 – 2008: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 准教授 … More 2002 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授 2001: Tokyo Medical and Dental University, Medical Research Division, Associate Professor, 医歯学総合研究科, 助教授 2000: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授 1998 – 1999: 東京医科歯科大学, 医学系研究科, 助教授 1996 – 1997: 熊本大学, 医学部, 講師 1992: 熊本大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 49060:Virology-related / Virology / Virology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator HIV-1 / インテグラーゼ / 逆転写 / 逆転写酵素 / HIV / LTR / att site / レトロウイルス / Integration / Integrase … More / 核内輸送 / Gemin2 / レンチウイルスベクター / siRNA / 核内移行 / Rch-1 / 核移行 / インテグレース / integrase / integration / ゲノム複製 / ゲノム / 酵素 / 核酸 / 蛋白質 / インテグラーぜ / 転写 / RNaseH / RNA / gene expression / proviral DNA / pseudo type / Endogenous RT / Reverse transcription / Zinc finger / 多量体形成 / 核局在 / RNA干渉 / Gemin 2 / cDNA合成 / ウイルスゲノム / プロテアゾーム分解 / インテグレーション / Transportin / 組み込み / 逆転写過程 / cDNA / 逆転写反応 / H1プロモーター / transportin / HSP 70 / importin / Vpr / GFP / Zn^<2+>フィンガー / zinc finger … More Except Principal Investigator HIV-1 / Nuclear export / Integration / Retrovirus / Chemokine receptor / NF-kappaB / CD4(+) T cell / AIDS / サブタイプEゲノム / アクセサリー蛋白 / 逆転写 / 糖鎖 / CD26 / SDFA / SIV / サル細胞 / RANTES / 阻害剤 / Nef / gp41 / 核内因子 / REV / インテグレース / TAT / ゲノム / 核外移行 / インテグレーション / レトロウイルス / ケモカインレセプター / NF-κB / CD4陽性T細胞 / エイズ / HIV / TSP / HAM / 細胞性免疫応答 / キラーT細胞 / HTLV-I Less

Elucidation of retrovirus reverse transcription mechanism regulated by integrase.Principal Investigator
- Principal Investigator
  
  Masuda Takao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Tokyo Medical and Dental University
Reconstitution of reverse transcription in vitro.Principal Investigator
- Principal Investigator
  
  Masuda Takao
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University
ヒト免疫不全ウイルスのゲノム動態と宿主因子の解析Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HIVゲノムの核内輸送に関与するウイルスおよび宿主因子の解析Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HIVインテグラーゼの機能ドメイン解析Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HIVインテグラーゼの新規機能ドメイン解析Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HIV-1インテグレースの感染初期過程における機能の多様性Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HIV-1インテグレースZn^<2+>フィンガー様領域の構造と機能に関する研究Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replication
- Principal Investigator
  
  KOYANAGI Yoshio, 永井美之
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  TOHOKU UNIVERSITY
  The University of Tokyo
HIV-1インテグレースのZn^<2+>フィンガー様領域の機能に関する研究Principal Investigator
- Principal Investigator
  
  増田貴夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Functional analysis of HIV-1 integrase and attachment sitePrincipal Investigator
- Principal Investigator
  
  MASUDA Takao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
HTLV-I感染疾患における細胞性免疫の標的抗原の検索
- Principal Investigator
  
  神奈木真理
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University

All 2023 2022 2021 2020 2017 2016 2015 2009 2008 2007

All Journal Article Presentation

[Journal Article] Cis-Allosteric Regulation of HIV-1 Reverse Transcriptase by Integrase2023
- Author(s)
  Masuda Takao、Kotani Osamu、Yokoyama Masaru、Abe Yuya、Kawai Gota、Sato Hironori
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 1 Pages: 31-31
- DOI
  10.3390/v15010031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07525
[Journal Article] Involvement of EZH2 inhibition in lenalidomide and pomalidomide-mediated growth suppression in HTLV-1-infected cells2021
- Author(s)
  Kondo Nobuyo, Nagano Yoshiko, Hasegawa Atsuhiko, Ishizawa Miku, Katagiri Kuniko, Yoneda Takeru, Masuda Takao, Kannagi Mari
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 574 Pages: 104-109
- DOI
  10.1016/j.bbrc.2021.08.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07512, KAKENHI-PROJECT-20K07525
[Journal Article] Short‐term cultured autologous peripheral blood mononuclear cells as a potential immunogen to activate Tax‐specific CTL response in adult T‐cell leukemia patients2021
- Author(s)
  Ishizawa Miku、Ganbaatar Undrakh、Hasegawa Atsuhiko、Takatsuka Natsuko、Kondo Nobuyo、Yoneda Takeru、Katagiri Kuniko、Masuda Takao、Utsunomiya Atae、Kannagi Mari
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 3 Pages: 1161-1172
- DOI
  10.1111/cas.14800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07512, KAKENHI-PROJECT-20K07525
[Journal Article] Influence of the 5′-terminal sequences on the 5′-UTR structure of HIV-1 genomic RNA2021
- Author(s)
  Obayashi Camille Michiko、Shinohara Yoko、Masuda Takao、Kawai Gota
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 10920-10920
- DOI
  10.1038/s41598-021-90427-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07525
[Journal Article] Critical Contribution of Tyr15 in the HIV-1 Integrase (IN) in Facilitating IN Assembly and Nonenzymatic Function through the IN Precursor Form with Reverse Transcriptase.2017
- Author(s)
  Takahata T, Takeda E, Tobiume M, Tokunaga K, Yokoyama M, Huang YL, Hasegawa A, Shioda T, Sato H, Kannagi M, Masuda T.
- Journal Title
  
  J Virol
  
  Volume: 91 Issue: 1
- DOI
  10.1128/jvi.02003-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-15K15139, KAKENHI-PROJECT-16K08824
[Journal Article] Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels2016
- Author(s)
  Nomaguchi M, Doi N, Sakai Y, Ode H, Iwatani Y, Ueno T, Matsumoto Y, Miyazaki Y, Masuda T, and Adachi A
- Journal Title
  
  Journal of Virology
  
  Volume: 90 Issue: 9 Pages: 4563-4578
- DOI
  10.1128/jvi.02939-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04740, KAKENHI-PROJECT-15K15139
[Journal Article] Fate of HIV-1 cDNA intermediates during reverse transcription is dictated by transcription initiation site of virus genomic RNA.2015
- Author(s)
  Masuda T, Sato Y, Huang Y, Koi S, Takahata T, Hasegawa A, 　Kawai G, 　Kannagi M.
- Journal Title
  
  Fate of HIV-1 cDNA intermediates during reverse transcription is dictated by transcription initiation site of virus genomic RNA.
  
  Volume: 5 Issue: 1 Pages: 17680-17680
- DOI
  10.1038/srep17680
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15139
[Journal Article] Interplay of HIV integrase with host factors2008
- Author(s)
  Masuda T
- Journal Title
  
  The Journal of AIDS Research 10
  
  Pages: 3-9
- NAID
  10026900928
- Data Source
  KAKENHI-PROJECT-19041028
[Journal Article] インテグラーゼと相互作用する宿主因子とHIV複製制御2008
- Author(s)
  増田貴夫
- Journal Title
  
  日本エイズ学会誌 (In press)
- NAID
  10026900928
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] 転写開始点が異なる複数種のHIV-1 RNAによる機能的分業の分子メカニズム解明2022
- Author(s)
  芳田剛, 増田貴夫
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] Influence of the 5’-terminal sequences on the 5′-UTR structure of the HIV-1 genomic RNA2021
- Author(s)
  Camille Michiko Obayashi, Yoko Shinohara, Takao Masuda, Gota Kawai
- Organizer
  日本核磁気共鳴学会年会 (22nd International Society of Magnetic Resonance Conference, 9th Asia-Pacific NMR symposiumおよび第60回電子スピンサイエンス学会と共催）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] HIV-1 RNAの機能的分業の分子機序解明2021
- Author(s)
  芳田剛，本田優輝，増田貴夫，山岡昇司
- Organizer
  第35回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] HIV-1 インテグラーゼによる逆転写酵素活性制御の分子基盤2021
- Author(s)
  増田貴夫, 阿部佑哉, 黄渝倫, 長谷川温彦,河合剛太, 神奈木真理
- Organizer
  第35回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] HIV-1 Pol中間産物の逆転写過程における酵素学的優位性2021
- Author(s)
  増田貴夫, 阿部佑哉, 黄渝倫, 長谷川温彦,河合剛太, 神奈木真理
- Organizer
  68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] HIV-1 RNAの5’末端塩基修飾による逆転写反応制御機構の解明2020
- Author(s)
  増田貴夫、黄渝倫、阿部佑哉、長谷川温彦、河合剛太、神奈木真理
- Organizer
  第34回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] HIV-1ゲノムRNAの5'末端の違いが構造と機能に与える影響2020
- Author(s)
  大林カミーユ美智子，篠原陽子，増田貴夫，河合剛太
- Organizer
  第43回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07525
[Presentation] Role of 5’-end modification of HIV-1 RNA during reverse transcription2016
- Author(s)
  Yu-Lun Huang, Tatsuro Takahata、Atsuhiko Hasegawa, Gota Kawai Mari Kannagi and Takao Masuda
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌　（札幌コンベンションセンター）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K15139
[Presentation] HIV-1 RNA 5’ 末端配列の逆転写過程での重要性.2015
- Author(s)
  増田貴夫、佐藤洋子、黄渝倫、高畑辰郎、長谷川温彦、河合剛汰、神奈木真理.
- Organizer
  第29回　日本エイズ学会学術集会
- Place of Presentation
  東京ドームホテル、東京
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K15139
[Presentation] In vitro reconstitution of HIV-1 reverse transcription revealed an unprecedented role of 5f virus genomic RNA.or reverse transcription.2015
- Author(s)
  Masuda T, Sato Y, Huang Y, Koi S, Takahata T, Hasegawa A, 　Kawai G, 　Kannagi M.
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K15139
[Presentation] Augmentation of reverse transcriptase (RT) activity by HIV-1 integrates through interaction with a host factor, Gemin2, is critical for HIV-1 infectivity2009
- Author(s)
  Masuda T
- Organizer
  The 4th GERMAN-JAPANESE AIDS SYMPOSIUM
- Place of Presentation
  ボッカム、ドイツ
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] HIV-1インテグラーゼと宿主因子Gemin2との結合はHIV-1複製に重要である2008
- Author(s)
  増田貴夫
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] HIV-1インテグラーゼの核局在を規定するシス配列および宿主因子2008
- Author(s)
  増田貴夫
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] Functional evaluation of the interaction between HIV-1 integrase and its interactor Gemin22008
- Author(s)
  Masuda T
- Organizer
  The 3rd International Conference on Retroviral Integrase
- Place of Presentation
  ウッズホール、アメリカ合衆国
- Year and Date
  2008-09-17
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] Gemin2アイソフォームの発現プロファイルとHIV-1複製2008
- Author(s)
  増田貴夫
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] HIV-1インテグラーゼと宿主因子Gemin2との結合はHIV-1複製に重要である2008
- Author(s)
  増田貴夫
- Organizer
  第22回日本エイズ学会
- Place of Presentation
  大阪
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] Interaction, of HIV-1 integrase with Gemin2 stimulates reverse transcription2008
- Author(s)
  Masuda T
- Organizer
  US-Japan AIDS Meeting
- Place of Presentation
  東京
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-19041028
[Presentation] インテグラーゼと相互作用する宿主因子とHIV複製制御2007
- Author(s)
  増田貴夫
- Organizer
  第21回日本エイズ学会シンポジウム「HIV増殖とその制御」
- Place of Presentation
  広島国際会議場
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19041028

1. HARADA Shinji (60173085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KOYANAGI Yoshio (80215417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OKAMOTO Takashi (40146600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHIODA Tatsuo (00187329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. SHIDA Hisatoshi (00144395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 神奈木真理 (80202034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 永井美之 (20022874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 足立昭夫 (90127043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋秀宗 (70260271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 生田和良 (60127181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IWATANI Yasumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masuda Takao 増田 貴夫

増田 貴夫 マスダ タカオ

MASUDA Takao 増田 貴夫

Research Projects

Research Products

Co-Researchers

Elucidation of retrovirus reverse transcription mechanism regulated by integrase.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reconstitution of reverse transcription in vitro.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト免疫不全ウイルスのゲノム動態と宿主因子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIVゲノムの核内輸送に関与するウイルスおよび宿主因子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIVインテグラーゼの機能ドメイン解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIVインテグラーゼの新規機能ドメイン解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIV-1インテグレースの感染初期過程における機能の多様性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIV-1インテグレースZn^<2+>フィンガー様領域の構造と機能に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replication

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIV-1インテグレースのZn^<2+>フィンガー様領域の機能に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Functional analysis of HIV-1 integrase and attachment sitePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HTLV-I感染疾患における細胞性免疫の標的抗原の検索

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Cis-Allosteric Regulation of HIV-1 Reverse Transcriptase by Integrase2023

Author(s)

Journal Title

DOI

Masuda Takao 増田貴夫

増田貴夫マスダタカオ

MASUDA Takao 増田貴夫