TAGAWA Kazuhiko 田川一彦

… Alternative Names

田川一彦タガワカズヒコ

KAZUHIKO Tagawa 田川一彦

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Researcher Number	80245795
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 東京医科歯科大学, 難治疾患研究所, 准教授 2016: 東京医科歯科大学, 難治疾患研究所, 准教授 2012 – 2014: 東京医科歯科大学, 難治疾患研究所, 准教授 2006: 医科歯科大, 難治疾患研究所, 助手 2005: 東京医科歯科大学, 難治疾患研究所, 助手 … More 2001: 国立精神・神経センター, 神経研究所・疫病研究第一部, 研究員 2001: National Institute of Neuroscience, NCNP, Research Scientist, 神経研究所・疾病研究第一部, 研究員 2000: 国立精神・神経センター, 神経研究所, 研究員 1992 – 1993: 上智大学, 理工学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Nerve anatomy/Neuropathology / Neuroscience in general / Nerve anatomy/Neuropathology Except Principal Investigator Neurology / 神経内科学
Keywords	Principal Investigator MARCKS / 超早期病態 / アルツハイマー病 / HMGB1 / ポリグルタミン病 / 超早期 / MARCKSL1 / リン酸化シグナル / リン酸化タンパク質 / シグナル伝達 … More / プロテオーム / 痴呆 / 脳神経疾患 / 神経科学 / リン酸化プロテオーム解析 / 過食 / GAPDH / リン酸化プロテオーム / PQBP1 / 早期病態 / 神経変性疾患 / アミロイドβ / タウ / SRRM2 / アタキシン１ / アタキシン1 / 脊髄小脳失調症I型 / システムバイオロジー解析 / プロテオーム解析 / 複合体タンパク質 / RPA1 / VCP / SCA1 / 脊髄小脳失調症Ⅰ型 / タンパク質複合体 / タンパク質相互作用 / アタキシン－１ / 脊髄小脳失調症１型 / 神経細胞死 / Hsp70 / ハンチンチン / ハンチントン病 … More Except Principal Investigator Fukutin / Extrancelular matrix / Basal 1amina / Dystrog1ycan / integrin / Laminin / Merosin / Congenital muscular dysrtophy / 再生 / 糖鎖修飾 / フクチン / 細胞外マトリックス / 基底膜 / ジストログリカン / インテグリン / ラミニン / メロシン / 先天性筋ジストロフィー / treatment / Dystrophin / Dystrophy / 治療 / ジストロフィン / 筋ジストロフィー Less

超早期アルツハイマー病におけるリン酸化タンパク質の病態分子機構の解明Principal Investigator
- Principal Investigator
  
  田川一彦
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Tokyo Medical and Dental University
Study of pathological protein phosphorylation changes in early-phase Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  TAGAWA Kazuhiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical and Dental University
Study of molecular pathology using proteome analyses for protein complexes in Spinocerebellar ataxia type 1Principal Investigator
- Principal Investigator
  
  KAZUHIKO Tagawa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University
小脳神経細胞特異的に発現誘導されるHsp70を制御する因子の同定と治療への応用Principal Investigator
- Principal Investigator
  
  田川一彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Medical and Dental University
The roles of laminin and its membrane receptors on muscular dystrophies
- Principal Investigator
  
  HAYASHI Yuko,K.
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Institute of Neuroscience, NCNP
Role of dystrophin-related protein in the pathogenesis of Duchenne muscular dystrophy.
- Principal Investigator
  
  ISHIURA Shoichi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経内科学
- Research Institution
  Institute of Molecular and Cellular Biosciences, The University of Tokyo

All 2020 2019 2018 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology2020
- Author(s)
  Tanaka Hikari, Tagawa Kazuhiko, Okazawa Hitoshi et al.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 507-507
- DOI
  10.1038/s41467-020-14353-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07817, KAKENHI-PROJECT-18K14840, KAKENHI-PROJECT-19H01042, KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03587
[Journal Article] The intellectual disability gene PQBP1 rescues Alzheimer’s disease pathology2018
- Author(s)
  Tanaka Hikari、Kondo Kanoh、Chen Xigui、Homma Hidenori、Tagawa Kazuhiko、Kerever Aurelien、Aoki Shigeki、Saito Takashi、Saido Takaomi、Muramatsu Shin-ichi、Fujita Kyota、Okazawa Hitoshi
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 23 Issue: 10 Pages: 2090-2110
- DOI
  10.1038/s41380-018-0253-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07097, KAKENHI-PROJECT-16K07040, KAKENHI-PROJECT-16H02655
[Journal Article] Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology2018
- Author(s)
  Fujita Kyota、Homma Hidenori、Kondo Kanoh、Ikuno Masashi、Yamakado Hodaka、Tagawa Kazuhiko、Murayama Shigeo、Takahashi Ryosuke、Okazawa Hitoshi
- Journal Title
  
  eneuro
  
  Volume: 5 Issue: 4 Pages: 0217-18
- DOI
  10.1523/eneuro.0217-18.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05698, KAKENHI-PROJECT-16K07040, KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-16K09672
[Journal Article] Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex2018
- Author(s)
  Inoue Seika、Hayashi Kanehiro、Fujita Kyota、Tagawa Kazuhiko、Okazawa Hitoshi、Kubo Ken-ichiro、Nakajima Kazunori
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 39 Issue: 4 Pages: 678-691
- DOI
  10.1523/jneurosci.1634-18.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06842, KAKENHI-PROJECT-18K07855, KAKENHI-PROJECT-18K19379, KAKENHI-PROJECT-15H02355, KAKENHI-PROJECT-16K07040, KAKENHI-PROJECT-16H02655, KAKENHI-PLANNED-16H06482
[Journal Article] HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease2016
- Author(s)
  Fujita, K., Motoki, K., Tagawa, K., Chen, X., Hama, H., Nakajima, K., Homma, H., Tamura, T., Watanabe, H., Katsuno, M., Matsumi, C., Kajikawa, M., Saito, T., Saido, T., Sobue, G., Miyawaki, A., Okazawa, H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 31895-31895
- DOI
  10.1038/srep31895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-26290019, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-16K07040
[Journal Article] Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.2015
- Author(s)
  Tagawa K, Homma H, Saito A, Fujita K, Chen X, Imoto S, Oka T, Ito H, Motoki K, Yoshida C, Hatsuta H, Murayama S, Iwatsubo T, Miyano S, Okazawa H.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 24 Issue: 2 Pages: 540-58
- DOI
  10.1093/hmg/ddu475
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22110001, KAKENHI-PLANNED-22110002, KAKENHI-PROJECT-24500378, KAKENHI-PROJECT-26640037
[Journal Article] Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.2014
- Author(s)
  Barclay, S.S., Tamura, T., Ito H., Fujita, K., Tagawa, K., Shimamura, T., Katsuta, A., Shiwaku, H., Sone, M., Imoto, S., Miyano, S. and Okazawa, H.
- Journal Title
  
  Hum Mol Genet
  
  Volume: 23 Issue: 5 Pages: 1345-1364
- DOI
  10.1093/hmg/ddt524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22110001, KAKENHI-PLANNED-22110002, KAKENHI-PROJECT-23500401, KAKENHI-PROJECT-24500378, KAKENHI-PROJECT-24700374, KAKENHI-PROJECT-25730173
[Journal Article] HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.2014
- Author(s)
  Ito H, Fujita K, Tagawa K, Chen X, Homma H, Sasabe T, Shimizu J, Shimizu S, Tamura T, Muramatsu S, Okazawa H.
- Journal Title
  
  EMBO Mol Med.
  
  Volume: 7 Issue: 1 Pages: 78-101
- DOI
  10.15252/emmm.201404392
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22110001, KAKENHI-PROJECT-24500378, KAKENHI-PROJECT-26350982, KAKENHI-PROJECT-26640037
[Journal Article] A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.2013
- Author(s)
  Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H.
- Journal Title
  
  Nat Commun.
  
  Volume: 4 Issue: 1 Pages: 1816-1816
- DOI
  10.1038/ncomms2828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-ORGANIZER-22110001, KAKENHI-PLANNED-22110002, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23500401, KAKENHI-PROJECT-24500378, KAKENHI-PROJECT-24700374, KAKENHI-PROJECT-25640066
[Journal Article] ハンチントン病のバイオマーカー研究2012
- Author(s)
  田川一彦
- Journal Title
  
  実験医学
  
  Volume: 30 Pages: 2572-2576
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 発達障害原因遺伝子PQBP1はアルツハイマー病態を制御する2020
- Author(s)
  田中ひかり、近藤和、陳西貴、本間秀典、藤田慶大、田川一彦、岡澤均
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K07817
[Presentation] YAP依存的ネクローシスは超早期アルツハイマー病態を制御する2020
- Author(s)
  田中ひかり、本間秀典、藤田慶大、近藤和、金キョウシン、田川一彦、岡澤均
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K07817
[Presentation] 発達障害原因遺伝子PQBP1はアルツハイマー病態を制御する2019
- Author(s)
  4.田中ひかり、近藤和、陳西貴、本間秀典、田川一彦、Aurelian Kerever、青木茂樹、斉藤貴志、西道隆臣、村松慎一、藤田慶大、岡澤均
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07817
[Presentation] The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology.2019
- Author(s)
  Hikari Tanaka, Kanoh Kondo, Xigui Chen, Hidenori Homma, Kazuhiko Tagawa, Aurelian Kerever, Shigeki Aoki, Takashi Saito, Takaomi Saido, Shin-ichi Muramatsu, Kyota Fujita, Hitoshi Okazawa
- Organizer
  神経科学会 NEURO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07817
[Presentation] Ser46-phosphorylated MARCKS is a common mechanism of pre-aggregation neurite degeneration in across multiple dementia2019
- Author(s)
  Kyota Fujita, Hidenori Homma, Kanoh Kondo, Kazuhiko Tagawa, Hitoshi Okazawa
- Organizer
  神経科学会 NEURO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07817
[Presentation] Developmental YAPdeltaC determines adult pathology in a mouse model of spinocerebellarataxia type 1.2018
- Author(s)
  藤田慶大、毛瀅、内田成則、陳西貴、塩飽裕紀、田村拓也、伊藤日加瑠、本間秀典、田川一彦、岡澤均
- Organizer
  日本神経学会
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] Developmental YAPdeltaC determines adult　pathology in a model of spinocerebellar ataxia type 12018
- Author(s)
  Kazuhiko Tagawa, Kyota Fujita Ying Mao, Shigenori Uchida, Xigui Chen, Kei Watase, Hidenori Homma, Marius Sudol, Hitoshi Okazawa
- Organizer
  日本神経科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] 発生期マウス大脳新皮質深部において、リーリン- DBNLシグナルはNカドヘリン/α-N-カテニンを介して神経細胞移動を制御する」 “Reelin-DBNL signaling regulates neuronal migration via N-cadherin/α -N-catenin complex in the intermediate zone and multipolar cell accumulate zone of the developing mouse cerebral neocortex2018
- Author(s)
  Seika Inoue, Kanehiro Hayashi, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa Ken-ichiro Kubo,Kazunori Nakajima
- Organizer
  日本生物学的精神医学会・日本神経化学会
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] ハンチントン病における新規ネクローシスTRIADの分子病態（A novel form of necrosis, TRIAD, in Huntington’s disease）2018
- Author(s)
  藤田慶大、Ying Mao、陳西貴、山西恵美子、本間秀典、田川一彦、岡澤均
- Organizer
  日本神経科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing2018
- Author(s)
  Hikari Tanaka, Ying Mao, Takuya Tamura, Yoshie Yuki, Daisu Abe, Hidenori Homma,Kazuhiko Tagawa, Hitoshi Okazawa
- Organizer
  日本神経科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] アルツハイマー病と前頭側頭葉変性症に共通する異常タウリン酸化とシナプス障害2018
- Author(s)
  藤田慶大、陳西貴、本間秀典、田川一彦、岡澤均、
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] 網羅的リン酸化プロテオーム解析による早期AD病態の解明2016
- Author(s)
  田川　一彦
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2016-07-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07040
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療への試み2013
- Author(s)
  田川一彦
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療の試み2013
- Author(s)
  田川一彦
- Organizer
  第54回日本神経病理学会総会学術研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] HMGB1を用いた脊髄小脳変性症１型モデルマウス治療の試み2013
- Author(s)
  田川一彦
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 脊髄小脳失調症1 型におけるDNA損傷修復異常のコアネットワーク解析
- Author(s)
  田村拓也、Barclay S Sam、藤田慶大、伊藤日加瑠、本木和美、島村徹平、田川一彦、勝田明寿香、曽根雅紀、井元清哉、宮野悟、岡澤均
- Organizer
  日本神経学会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 情報科学を用いた神経変性疾患の病態解明
- Author(s)
  5.田村拓也、Barclay S Sam、藤田慶大、伊藤日加瑠、本木和美、島村徹平、田川一彦、勝田明寿香、曽根雅紀、井元清哉、宮野悟、岡澤均
- Organizer
  神経科学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] TERA/VCP/p97のDNA修復機能不全は複数の神経変性疾患に関与する
- Author(s)
  藤田慶大、中村蓉子、岡努、伊藤日加瑠、田村拓也、田川一彦、笹邊俊和、勝田明寿香、本木和美、塩飽裕紀、吉田千里、曽根雅紀、岡澤均
- Organizer
  日本神経学会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 複数のポリグルタミン病に共通するTERA/VCP/p97のDNA損傷修復機能不全
- Author(s)
  6.藤田慶大、中村蓉子、岡努、伊藤日加瑠、田村拓也、田川一彦、笹邊俊和、勝田明寿香、本木和美、塩飽裕紀、吉田千里、曽根雅紀、岡澤均
- Organizer
  神経科学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 脊髄小脳失調症1 型におけるDNA損傷修復異常のコアネットワーク解析
- Author(s)
  田村拓也、Barclay S Sam、藤田慶大、伊藤日加瑠、本木和美、島村徹平、田川一彦、勝田明寿香、曽根雅紀、井元清哉、宮野悟、岡澤均
- Organizer
  本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 複数のポリグルタミン病に共通するTERA/VCP/p97のDNA損傷修復機能不全
- Author(s)
  藤田慶大、中村蓉子、岡努、伊藤日加瑠、田村拓也、田川一彦、笹邊俊和、勝田明寿香、本木和美、塩飽裕紀、吉田千里、曽根雅紀、岡澤均
- Organizer
  日本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-24500378
[Presentation] 脊髄小脳失調症1型の分子病態コアネットワークの解明
- Author(s)
  7.田村拓也、Barclay S Sam、藤田慶大、伊藤日加瑠、本木和美、島村徹平、田川一彦、勝田明寿香、曽根雅紀、井元清哉、宮野悟、岡澤均
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24500378

1. 藤田慶大 (40792205)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. ISHIURA Shoichi (10158743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SORIMACHI Hiroyuki (10211327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HAYASHI Yuko,K. (50238135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OKAZAWA Hitoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. KATSUNO Masahisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ケレベールオーレリアン

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 祖父江元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岩坪威

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高橋良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 林周宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAGAWA Kazuhiko 田川 一彦

田川 一彦 タガワ カズヒコ

KAZUHIKO Tagawa 田川 一彦

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超早期アルツハイマー病におけるリン酸化タンパク質の病態分子機構の解明Principal Investigator

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Study of pathological protein phosphorylation changes in early-phase Alzheimer's diseasePrincipal Investigator

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Study of molecular pathology using proteome analyses for protein complexes in Spinocerebellar ataxia type 1Principal Investigator

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小脳神経細胞特異的に発現誘導されるHsp70を制御する因子の同定と治療への応用Principal Investigator

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The roles of laminin and its membrane receptors on muscular dystrophies

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Role of dystrophin-related protein in the pathogenesis of Duchenne muscular dystrophy.

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[Journal Article] YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology2020

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[Journal Article] The intellectual disability gene PQBP1 rescues Alzheimer’s disease pathology2018

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[Journal Article] Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology2018

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[Journal Article] Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex2018

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[Journal Article] HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease2016

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[Journal Article] Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.2015

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[Journal Article] Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.2014

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[Journal Article] HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.2014

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TAGAWA Kazuhiko 田川一彦

田川一彦タガワカズヒコ

KAZUHIKO Tagawa 田川一彦

[Presentation] Developmental YAPdeltaC determines adult　pathology in a model of spinocerebellar ataxia type 12018