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Hara Eiji  原 英二

… Alternative Names

HARA Eiji  原 英二

原 英二  ハラ エイジ

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Researcher Number 80263268
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7821-3960
External Links
Affiliation (Current) 2025: 大阪大学, 微生物病研究所, 教授
Affiliation (based on the past Project Information) *help 2019 – 2025: 大阪大学, 微生物病研究所, 教授
2015 – 2016: 大阪大学, 微生物病研究所, 教授
2014: 公益財団法人がん研究会, がん研究所, 部長
2012 – 2014: 公益財団法人がん研究会, がん研究所がん生物部, 部長
2011: 公益財団法人 がん研究会, がん研究所・がん生物部, 部長 … More
2011: 公益財団法人がん研究会, がん研究所・がん生物部, 部長
2009 – 2010: Japanese Foundation For Cancer Research, 癌研究所がん生物部, 部長
2008 – 2010: Japanese Foundation For Cancer Research, 癌研究所がん生物部, 部長
2008: Japanese Foundation For Cancer Research, がん生物部, 部長
2004 – 2007: 徳島大学, ゲノム機能研究センター, 教授
1994: 大阪大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Pathological medical chemistry / Tumor biology / Broad Section I / Medium-sized Section 50:Oncology and related fields / Cell biology / Tumor biology / Biological Sciences
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Dermatology / Structural biochemistry / Biological Sciences
Keywords
Principal Investigator
癌 / シグナル伝達 / 細胞老化 / 発癌 / 発がん / 遺伝子 / 発現制御 / 老化 / 癌抑制 / 細胞周期 … More / ROS / ゲノム / イメージング / p53 / PKCδ / pRB / p16 / 腸内細菌 / ストレス / 加齢 / p16^<INK4a> / Tumor suppression / Cytokinesis / Cellular Senescence / 不死化 / PI3キナーゼ / 細胞質分裂 / 微生物 / 肥満 / 国際情報交換 / アポトーシス / 活性酸素種 / 液性因子 / がん微小環境 / インビボ・イメージング / 転写調節 / ルシフェラーゼ / p14^<ARF> / 可視化 / P16^<INK4a> / 発癌ストレス / 染色体 / ARF遺伝子座 / INK4A / CDK / Fbxo7 / 増殖刺激 / CDK6 / サイクリンD1 / CRM1 / LMP1 / EBウイルス / RB … More
Except Principal Investigator
c-Met / HGF / インジュリン / c-met / 血管新生 / 器官再生 / 次世代シーケンス / リスク診断 / NGS / 大腸フローラ / 口腔細菌叢 / 大腸マイクロバイオーム / 大腸癌 / 口腔 / 便 / 唾液 / 口腔常在菌 / 真菌叢 / 細菌叢 / 大腸がん / Solobacterium moorei / Peptostreptococcus / 歯周病菌 / 口腔マイクロバイオーム / 16S rRNA / 次世代シーケンサー / Fusobacterium nucleatum / マイクロバイオーム / skin cancer / bioluminescence in vivo imaging / p16^<INK4a> gene / BAC / 可視化 / p16^<Ink4a>遺伝子 / 皮膚癌 / イメージング / p16^<INK4a>遺伝子 / growth factor / injurin / organ regeneration / organogenesis / MET / 腎再生 / 肝再生 / hepatocyte growth factor / FGF / PDGF / カルシノーマ / IL-1 / 増殖因子 / 器官形成 / ゲノム医学 / リンパ管新生 / 転移 / がん浸潤 / がん微小環境 / ゲノム科学 / 生体イメージング / 生体材料 / シグナル伝達 / 微小環境 / c-sea / 肺線維症 / Ron / HLP / 上皮-間葉相互作用 / Met / Fas / 浸潤・転移 / 形態形成 / Sky / 劇症肝炎 / 遺伝子治療 / 心筋梗塞 / 脂肪肝 / 腫瘍血管新生 / LIMキナーゼ / HGFアンタゴニスト / 浸潤・転移阻止 / 慢性腎不全 / 肝硬変 Less
  • Research Projects

    (19 results)
  • Research Products

    (170 results)
  • Co-Researchers

    (39 People)
  •  加齢性発癌の制御に向けた細胞老化の発癌促進作用の解明Principal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      The University of Osaka
  •  Studies on the role of gut bacteria and cellular senescence in age-related carcinogenesis and its controlPrincipal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Osaka University
  •  Creation of colorectal cancer risk diagnosis and prevention concept by oral and colonic microbiome analysis

    • Principal Investigator
      Goto Yuichi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kagoshima University
  •  Study of obesity-associated carcinogenesis and its application to cancer preventionPrincipal Investigator

    • Principal Investigator
      Hara Eiji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Osaka University
      Japanese Foundation for Cancer Research
  •  Understanding of the anti-apoptotic mechanisms in senescent cellsPrincipal Investigator

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Roles and mechanisms of cellular senescence in cancer microenvironmentPrincipal Investigator

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Study on senescence-associated tumor promotionPrincipal Investigator

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  細胞老化の不可逆性を規定する分子機構の解明Principal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Integrative Research on Cancer Microenvironment Network

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  細胞老化の発癌制御に関する2面性とその調節に関する研究Principal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Visualizing the dynamics of senescence response in vivoPrincipal Investigator

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  分子イメージングを用いた新しい発癌リスク評価システムの開発Principal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Studies on the irreversibility of cellular senescence and its role in vivoPrincipal Investigator

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokushima
  •  Regulation of INK4a/ARF gene locus and its role in cellular senescencePrincipal Investigator

    • Principal Investigator
      HARA Eiji
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
      The University of Tokushima
  •  EBウイルスLMP1癌蛋白によるp16^<INK4a>/RB経路阻害機構の解明Principal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  増殖刺激によるサイクリンD1キナーゼ活性化機構の解明Principal Investigator

    • Principal Investigator
      原 英二
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Induction of p16^<INK4a> gene expression by oncogenic stress is involved in the tumor suppression mechanism of skin cancer

    • Principal Investigator
      OHTANI Naoko
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Tokushima
  •  HGFならびにLIMキナーゼによる高次細胞機能の調節とがん特性の研究

    • Principal Investigator
      NAKAMURA Toshikazu
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Molecular mechanisms of organ regeneration and homeoslasis by injurin/HGF system.

    • Principal Investigator
      NAKAMURA Toshikazu
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 細胞周期アッセイ法がん分子標的治療研究マニュアル2009

    • Author(s)
      高橋暁子、原英二
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Book] がん分子標的治療研究マニュアル(鶴尾隆/曽根三郎編)(細胞周期アッセイ法)2009

    • Author(s)
      高橋暁子、原英二
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Journal Article] Crosstalk between gut microbiota and cellular senescence: a vicious cycle leading to aging gut2024

    • Author(s)
      Kawamoto Shimpei、Hara Eiji
    • Journal Title

      Trends in Cell Biology

      Volume: 13 Issue: 8 Pages: 626-635

    • DOI

      10.1016/j.tcb.2023.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Journal Article] Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype2023

    • Author(s)
      Matsudaira Tatsuyuki、Nakano Sosuke、Konishi Yusuke、Kawamoto Shimpei、Uemura Ken、Kondo Tamae、Sakurai Koki、Ozawa Takaaki、Hikida Takatoshi、Komine Okiru、Yamanaka Koji、Fujita Yuki、Yamashita Toshihide、Matsumoto Tomonori、Hara Eiji
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 665-665

    • DOI

      10.1038/s42003-023-05027-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06481, KAKENHI-PROJECT-21K18557, KAKENHI-PROJECT-22KJ2043, KAKENHI-PROJECT-22H00457, KAKENHI-PROJECT-23K22376, KAKENHI-PROJECT-23K24205
  • [Journal Article] Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota2023

    • Author(s)
      Kawamoto Shimpei、Uemura Ken、Hori Nozomi、Takayasu Lena、Konishi Yusuke、Katoh Kazutaka、Matsumoto Tomonori、Suzuki Masae、Sakai Yusuke、Matsudaira Tatsuyuki、Adachi Takahiro、Ohtani Naoko、Standley Daron M.、Suda Wataru、Fukuda Shinji、Hara Eiji
    • Journal Title

      Nature Cell Biology

      Volume: 25 Issue: 6 Pages: 865-876

    • DOI

      10.1038/s41556-023-01145-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06481, KAKENHI-PROJECT-22H00457, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K24798
  • [Journal Article] Are intratumoral microbiota involved in the progression of intraductal papillary mucinous neoplasms of the pancreas?2023

    • Author(s)
      Hozaka Yuto、Oi Hideyuki、Satake Souichi、Uchino Yoshinori、Goto Yuichi、Idichi Tetsuya、Tanoue Kiyonori、Yamasaki Yoichi、Kawasaki Yota、Mataki Yuko、Kurahara Hiroshi、Nakajo Akihiro、Higashi Michiyo、Tanimoto Akihide、Sugiura Tsuyoshi、Ohtsuka Takao
    • Journal Title

      Surgery

      Volume: 173 Issue: 2 Pages: 503-510

    • DOI

      10.1016/j.surg.2022.10.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10224, KAKENHI-PROJECT-22K19567, KAKENHI-PROJECT-22K16514, KAKENHI-PROJECT-20H03753, KAKENHI-PROJECT-19K10361, KAKENHI-PROJECT-21K16453, KAKENHI-PROJECT-21K06889
  • [Journal Article] RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells2022

    • Author(s)
      Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.
    • Journal Title

      Commun Biol

      Volume: 5 Issue: 1 Pages: 1420-1420

    • DOI

      10.1038/s42003-022-04369-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-22H00457, KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-22KJ3105, KAKENHI-PROJECT-21K19419, KAKENHI-PROJECT-20K16344, KAKENHI-PROJECT-19H03156, KAKENHI-PLANNED-18H05532, KAKENHI-PLANNED-17H06426, KAKENHI-PUBLICLY-22H05599, KAKENHI-PROJECT-23K23810
  • [Journal Article] Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma2022

    • Author(s)
      Yamagishi R, Kamachi F, Nakamura M, Yamazaki S, Kamiya T, Takasugi M, Cheng Y, Nonaka Y, Yukawa-Muto Y, Thuy LTT, Harada Y, Arai T, Loo TM, Yoshimoto S, Ando T, Nakajima M, Taguchi H, Ishikawa T, Akiba H, Miyake S, Kubo M, Iwakura Y, Fukuda S, Chen WY, Kawada N, Rudensky A, Nakae S, Hara E, Ohtani N
    • Journal Title

      Science Immunology

      Volume: 7 Issue: 72 Pages: abl7209

    • DOI

      10.1126/sciimmunol.abl7209

    • URL

      https://ocu-omu.repo.nii.ac.jp/records/2020472

    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22H00457, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03472, KAKENHI-PROJECT-21H02964, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-20K16309, KAKENHI-PROJECT-23K24322
  • [Journal Article] Colorectal Cancer Patients Have Four Specific Bacterial Species in Oral and Gut Microbiota in Common?A Metagenomic Comparison with Healthy Subjects2021

    • Author(s)
      Uchino Yoshinori、Goto Yuichi、Konishi Yusuke、Tanabe Kan、Toda Hiroko、Wada Masumi、Kita Yoshiaki、Beppu Mahiro、Mori Shinichiro、Hijioka Hiroshi、Otsuka Takao、Natsugoe Shoji、Hara Eiji、Sugiura Tsuyoshi
    • Journal Title

      Cancers

      Volume: 13 Issue: 13 Pages: 3332-3332

    • DOI

      10.3390/cancers13133332

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10361, KAKENHI-PROJECT-21K08783
  • [Journal Article] Oral ulcers suspected to be caused by improper administration of bisphosphonate2019

    • Author(s)
      新田 哲也, 坂元 亮一, 平原 成浩, 松村 吉晃, 中村 康大, 後藤 雄一
    • Journal Title

      Japanese Journal of Oral and Maxillofacial Surgery

      Volume: 65 Issue: 9 Pages: 599-604

    • DOI

      10.5794/jjoms.65.599

    • NAID

      130007748571

    • ISSN
      0021-5163, 2186-1579
    • Year and Date
      2019-09-20
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10361
  • [Journal Article] Gut microbiota promotes obesity-associated liver cancer through PGE2-mediated suppression of antitumor immunity.2017

    • Author(s)
      Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo M, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N.
    • Journal Title

      Cancer Discov

      Volume: in press Issue: 5 Pages: 522-538

    • DOI

      10.1158/2159-8290.cd-16-0932

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H04699
  • [Journal Article] Exosomes maintain cellular homeostasis by excreting harmful DNA from cells2017

    • Author(s)
      Takahashi, A., Okada, R., Nagao, K., Kawamata, Y., Hanyu, A., Yoshimoto, S., Takasugi, M., Watanabe, S., Kanemaki, M.T., Obuse, C. & Hara, E.
    • Journal Title

      Nature Communications

      Volume: - Issue: 1 Pages: 15287-15287

    • DOI

      10.1038/ncomms15287

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-17K19618, KAKENHI-PUBLICLY-17H05628, KAKENHI-PLANNED-17H06426, KAKENHI-PLANNED-25116004, KAKENHI-PROJECT-16H04700, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-15K06942, KAKENHI-PROJECT-16K15095
  • [Journal Article] The impact of SASP and its potential as a therapeutic target for senescence-associated diseases.2017

    • Author(s)
      Watabnabe, S., Kawamoto, S., Ohtani, N., & Hara, E.
    • Journal Title

      Cancer Science

      Volume: - Issue: 4 Pages: 563-569

    • DOI

      10.1111/cas.13184

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26430116, KAKENHI-PROJECT-16H04699
  • [Journal Article] Mechanisms of action of bone morphogenetic proteins in cancer2016

    • Author(s)
      Davis H, Raja E, Miyazono K, Tsubakihara Y, Moustakas A.
    • Journal Title

      Cytokine Growth Factor Rev.

      Volume: 27 Pages: 81-92

    • DOI

      10.1016/j.cytogfr.2015.11.009

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-24390070, KAKENHI-PROJECT-15H05774
  • [Journal Article] In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line.2015

    • Author(s)
      Nanjo S, Yano S, et al.
    • Journal Title

      Cancer Sci

      Volume: 106 Issue: 3 Pages: 244-52

    • DOI

      10.1111/cas.12600

    • NAID

      120005830611

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22112010, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-24659403, KAKENHI-PROJECT-25860640, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462202
  • [Journal Article] Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice2015

    • Author(s)
      Seidai Sato, Yuka Kawamata, Akiko Takahashi, Yoshinori Imai, Aki Hanyu, Atsushi Okuma, Masaki Takasugi, Kimi Yamakoshi, Hiroyuki Sorimachi, Hiroaki Kanda, Yuichi Ishikawa, Saburo Sone, Yasuhiko Nishioka, Naoko Ohtani and Eiji Hara
    • Journal Title

      Nature communications

      Volume: 6 Issue: 1 Pages: 7035-7035

    • DOI

      10.1038/ncomms8035

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J06532, KAKENHI-PROJECT-14J10280, KAKENHI-PROJECT-14J10710, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26670418, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K19421, KAKENHI-PROJECT-25290046
  • [Journal Article] Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice.2015

    • Author(s)
      Sato, S., Kawamata, Y., Takahashi, A., Imai, Y., Hanyu, A., Okuma, A., Takasugi, M., Yamakoshi, K., Sorimachi, H., Kanda, H., Ishikawa, Y., Sone, S., Nishioka, Y., Ohtani, N., Hara, E.
    • Journal Title

      Nature Communications

      Volume: 6:7035 Pages: 1-10

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Journal Article] Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence.2015

    • Author(s)
      Brookes S, Gagrica S, Sanij E, Rowe J, Gregory FJ, Hara E, and *Peters G.
    • Journal Title

      Cell Cycle

      Volume: 14 Issue: 8 Pages: 1164-1173

    • DOI

      10.1080/15384101.2015.1010866

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250028
  • [Journal Article] Dysregulation of the Bmi-1/p16Ink4a pathway provokes an aging-associated decline of submandibular gland function.2015

    • Author(s)
      Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto-Uezumi M, Ohtani N, Hara E, Maruyama M.
    • Journal Title

      Aging Cell

      Volume: - Issue: 4 Pages: 1-9

    • DOI

      10.1111/acel.12337

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J10280, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-25861349
  • [Journal Article] Crosstalk between the RB-pathway and AKT signalling forms a Quiescence-Senescence switch.2014

    • Author(s)
      Imai, Y., Takahashi, A., Hanyuu, A., Hori, S., Sato, S., Naka, K., Hirao, A., Ohtani, N., Hara, E.
    • Journal Title

      Cell Reports

      Volume: 7 Issue: 1 Pages: 194-207

    • DOI

      10.1016/j.celrep.2014.03.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24650625, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25290046, KAKENHI-PROJECT-26250028
  • [Journal Article] Crosstalk between the Rb pathway and AKT signaling forms a quiescence-senescence switch2014

    • Author(s)
      Imai, Y., Takahashi, A., Hanyu, A., Sato, S., Naka, K., Hirao, A., Ohtani, N., Hara, E
    • Journal Title

      Cell Reports

      Volume: 7 Pages: 194-1207

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Obesity and cancer : gut microbial connection2014

    • Author(s)
      Ohtani, N., Yoshimoto, S., Hara, E
    • Journal Title

      Cancer Research

      Volume: 74 Pages: 1885-1889

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Necessary and sufficient role for a mitosis skip in senescence induction.2014

    • Author(s)
      Johmura Y, Shimada M, Misaki T, Naiki-Ito A, Miyoshi H, Motoyama N, Ohtani N, Hara E, Nakamura M, Morita A, Takahashi S, Nakanishi M.
    • Journal Title

      Mol.Cell

      Volume: 55 Issue: 1 Pages: 73-84

    • DOI

      10.1016/j.molcel.2014.05.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22118003, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24590369, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26860195
  • [Journal Article] An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.2014

    • Author(s)
      Demaria, M., Ohtani, N., Youssef, S.A., Rodier, F., Toussaint, W., Mitchell, J.R., Laberge, R.M., Vijg, J., Van Steeg, H., Dollé, M.E.T., Hoeijmakers, J.H.J., de Bruin, A., Hara, E.., Campisi, J.
    • Journal Title

      Developmental Cell

      Volume: 31 Issue: 6 Pages: 722-733

    • DOI

      10.1016/j.devcel.2014.11.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250028
  • [Journal Article] Obesity and Cancer: a gut microbial connection2014

    • Author(s)
      Ohtani, N.
    • Journal Title

      Cancer Research

      Volume: 74 Issue: 7 Pages: 1885-11889

    • DOI

      10.1158/0008-5472.can-13-3501

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24650625
  • [Journal Article] Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis2014

    • Author(s)
      Takagi S, Oh-hara T, Sato S, Gong B, Takami M, Fujita N.
    • Journal Title

      International Journal of Cancer

      Volume: 134 Issue: 11 Pages: 2605-2614

    • DOI

      10.1002/ijc.28602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112008, KAKENHI-PROJECT-25830125
  • [Journal Article] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome2013

    • Author(s)
      Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., Ishikawa, Y., Hara, E., Ohtani, N
    • Journal Title

      Nature

      Volume: 499 Pages: 97-101

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Roles and mechanisms of cellular senescence in regulation of tissue homeostasis2013

    • Author(s)
      Ohtani, N., Hara, E
    • Journal Title

      Cancer Sci

      Volume: 104 Pages: 525-530

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] DNA damage signaling triggers degradation of histone methyltransferases through APC/C^<Cdh1> in senescent cells2012

    • Author(s)
      Takahashi, A., Imai, Y., Yamakoshi, K., Kuninaka, S., Ohtani, N., Yoshimoto, S., Hori, S., Tachibana, M., Anderton, E., Takeuchi, T., Shinkai, Y., Peters, G., Saya, H. and Hara E
    • Journal Title

      Mol. Cell

      Volume: 45 Pages: 123-131

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells2012

    • Author(s)
      Akiko Takahashi
    • Journal Title

      Molecular Cell

      Volume: 45 Issue: 1 Pages: 123-131

    • DOI

      10.1016/j.molcel.2011.10.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J10697, KAKENHI-PLANNED-19057011, KAKENHI-PUBLICLY-22019043, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24590360, KAKENHI-PROJECT-24657155
  • [Journal Article] Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a2012

    • Author(s)
      Yamamizu, K., Fujihara, M., Tachibana, M., Katayama, S., Takahashi, A., Hara, E., Imai, H., Shinkai, Y., and Yamashita, J. K
    • Journal Title

      Cell Stem Cell

      Volume: 10 Pages: 759-770

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Cellular senescence : a double-edged sword in the fight against cancer2012

    • Author(s)
      Ohtani, N., Takahashi, A. Mann, D.J. and Hara, E
    • Journal Title

      Exp. Dermatol

      Volume: 21

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Development of mice without Cip/Kip CDK inhibitors2012

    • Author(s)
      Tateishi, Y., Matsumoto. A., Kanie, T., Hara, E., Nakayama, K., Nakayama, K.I
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 427 Pages: 285-292

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Reversion-inducing cysteine-rich protein with Kazal motifs (RECK) interferes with epidermal growth factor receptor (EGFR) signaling.2011

    • Author(s)
      Kitajima S., Miki T., Takegami Y., Kido Y., Noda M., Hara E., Shamma A., Takahashi C.
    • Journal Title

      Oncogene 30

      Pages: 737-750

    • Data Source
      KAKENHI-PROJECT-20390094
  • [Journal Article] E2FBP1 antagonizes the p16(INK4A)-Rb tumor suppressor machinery for growth suppression and cellular senescence by regulating promyelocytic leukemia protein stability2011

    • Author(s)
      Fukuyo, Y., Takahashi, A., Hara, E., Horikoshi, N., Pandita, T. K., Nakajima, T
    • Journal Title

      Int J Oral Sci

      Volume: 3 Pages: 200-208

    • Data Source
      KAKENHI-PROJECT-23300352
  • [Journal Article] Enhancement of ectopic osteoid formation following the dual release of bone morphogenetic protein-2 and Wnt1 inducible signaling pathway protein 1 from gelatin sponges2011

    • Author(s)
      Kohara, H., Tabata, Y.
    • Journal Title

      Biomaterials

      Volume: 32 Issue: 24 Pages: 5726-5732

    • DOI

      10.1016/j.biomaterials.2011.04.035

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002
  • [Journal Article] TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition.2011

    • Author(s)
      Shirakihara T, Miyazono K, et al.
    • Journal Title

      EMBO Journal

      Volume: 30 Pages: 783-795

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Journal Article] Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator seil.2010

    • Author(s)
      Fernandez-Marcos P.J., Pantoja C., Gonzalez-Rodriguez A., Martin N., Flores J.M., Valverde A.M., Hara E., Serrano M.
    • Journal Title

      PLoS One. 18

    • Data Source
      KAKENHI-PROJECT-20390094
  • [Journal Article] Intrinsic cooperation between p16^<INK4a> and p21^<Waf1/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S., Takahashi A., Motoi N., Yoshimoto S., Tajima T., Yamakoshi K., Hirao A., Yanagi S., Fukami K., Ishikawa Y., Sone S., Hara E., Ohtani N.
    • Journal Title

      Cancer Res. 70

      Pages: 9381-9390

    • Data Source
      KAKENHI-PROJECT-20390094
  • [Journal Article] Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation2009

    • Author(s)
      Inomata, K., Aoto, T., Binh, N.T., Okamoto, N., Tanimura, S., Wakayama, T., Iseki, S., Hara, E., Masunaga, T., Shimizu, H., Nishimura, E.K.
    • Journal Title

      Cell 137

      Pages: 1088-1099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Journal Article] Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation.2009

    • Author(s)
      Inomata K., Aoto T., Binh N.T., Okamoto N., Tanimura S., Wakayama T., Iseki S., Hara E., Masunaga T., Shimizu H., Nishimura E.K.
    • Journal Title

      Cell 137

      Pages: 1088-1099

    • Data Source
      KAKENHI-PROJECT-20390094
  • [Journal Article] Real-time in vivo imaging of p16Ink4a reveals cross-talk with p52009

    • Author(s)
      Yamakoshi, K., Takahashi, A., Hirota, F., Nakayama, R., Ishimaru, N., Kubo, Y., Mann, D.J., Ohmura, M., Hirao, A., Saya, H., Arase, S., Hayashi, Y., Nakao, K., Matsumoto, M., Ohtani, N., Hara, E.
    • Journal Title

      J. Cell Biol. 186

      Pages: 393-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Journal Article] Real-time in vivo imaging of p16^<Ink4a> reveals cross-talk with p53.2009

    • Author(s)
      Yamakoshi K., Takahashi A., Hirota F., Nakayama R., Ishimaru N., Kubo Y., Mann D.J., Ohmura M., Hirao A., Saya H., Arase S., Hayashi Y., Nakao K., Matsumoto M., Ohtani N., Hara E.
    • Journal Title

      J. Cell Biol. 186

      Pages: 393-407

    • Data Source
      KAKENHI-PROJECT-20390094
  • [Journal Article] Visualizing the dynamics of p21Waf1/Cip1 cyclin-dependent kinase inhibitor expression in living animals2007

    • Author(s)
      Ohtani, N., Imamura, Y., Yamakoshi, K., Hirota, F., Nakayama, R., Kubo, Y., Ishimaru, N., Takahashi, A., Hirao, A., Shimizu, T., Mann, D.J., Saya, H., Hayashi, Y., Arase, S., Matsumoto, M., Nakao, K., Hara, E.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 15034-15039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Journal Article] Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biol. 8

      Pages: 1291-1297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Journal Article] Epigenetic abnormalities in cutaneous squamous cell carcinomas : Frequent inactivation of the RBI/p16 and p53 pathways.2006

    • Author(s)
      Murao, K., Kubo, Y., Ohtani, N., Hara, E., Arase S
    • Journal Title

      British Journal of Dermatology 155

      Pages: 999-1005

    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] and Arase S Epigenetic abnormalities in cutaneous squamous cell carcinomas : Frequent inactivation of the RB1/p16 and p53 pathways.2006

    • Author(s)
      Murao, K., Kubo, Y., Ohtani, N., Hara, E.
    • Journal Title

      British Journal of Dermatology 155

      Pages: 999-1005

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biology 8

      Pages: 1291-1297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence.2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biology 8

      Pages: 1291-1297

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Mitogenic signalling and the p16INK4a/Rb pathway co-operate to enforce irreversible cellular senescence.2006

    • Author(s)
      Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S., Tahara, H., Nakayama, K., Nakayama, K.I., Ide, T., H., Saya, H., Hara, E.
    • Journal Title

      Nature Cell Biology 8

      Pages: 1291-1297

    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Epigenetic abnormalities in cutaneous squamous cell carcinomas : Frequent inactivation of the RB1/p16 and p53 pathways.2006

    • Author(s)
      Murao, K., Kubo, Y., Ohtani, N., Hara, E., Arase S
    • Journal Title

      British Journal of Dermatology 155

      Pages: 999-1005

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53.2005

    • Author(s)
      Maehara K, Yamakoshi K, Ohtani N, Kubo Y, Takahashi A, Arase S, Jones N, Hara E
    • Journal Title

      Journal of Cell Biology 168

      Pages: 552-560

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390318
  • [Journal Article] Transforming activity of Fbxo7 is mediated specifically through regulation of cyclinD/cdk62005

    • Author(s)
      Laman, H., Funes, J., Ye, H., Henderson, S., Galinanes-Garcia, L., Hara, E., Knowles, P., McDonald, N., Boshoff, C.
    • Journal Title

      EMBO J. 24

      Pages: 3104-3116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Journal Article] Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p532005

    • Author(s)
      Kayoko Maehara
    • Journal Title

      The Journal of Cell Biology 168

      Pages: 553-560

    • Data Source
      KAKENHI-PROJECT-16026231
  • [Journal Article] Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p532005

    • Author(s)
      Kayoko Maehara
    • Journal Title

      The Journal of Cell Biology 168

      Pages: 553-560

    • Data Source
      KAKENHI-PROJECT-17013064
  • [Journal Article] Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p532005

    • Author(s)
      Kayoko Maehara
    • Journal Title

      The Journal of Cell Biology 168

      Pages: 553-560

    • Data Source
      KAKENHI-PROJECT-16021242
  • [Journal Article] Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p532005

    • Author(s)
      Maehara, K., Yamakoshi, K., Ohtani, N., Kubo, Y., Takahashi, A., Arase, S., Jones, N., Hara, E.
    • Journal Title

      J. Cell Biol. 167

      Pages: 553-560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] 細胞老化のメカニズムと役割 ー 細胞老化研究の光と影 ー2023

    • Author(s)
      原英二
    • Organizer
      CVMW2023 KOBE
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Toward the identification and control of the causes of cellular senescence induction in vivo2023

    • Author(s)
      Eiji Hara
    • Organizer
      Seno-Therapeutics Summit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Cellular senescence and cancer: relevance to microorganisms2023

    • Author(s)
      原英二
    • Organizer
      日本生理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Role of cellular senescence in aging and cancer: Relationship with microorganisms2023

    • Author(s)
      Eiji Hara
    • Organizer
      8th International Cell Senescence Association Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Cellular senescence : relevance to microorganisms2023

    • Author(s)
      Eiji Hara
    • Organizer
      Wiggers-Bernard Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Induction of cellular senescence by viral infection and its effects on the host2023

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] The role of cellular senescence in aging and cancer: Molecular analysis of host-microbial relationships2023

    • Author(s)
      Eiji Hara
    • Organizer
      IAGG/Asia Oceania Regional Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Role of cellular senescence in aging and cancer: Relationship with microorganisms2023

    • Author(s)
      Eiji Hara
    • Organizer
      Australian Cell Cycle, DNA Repair and Telomere Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] The Role of Cellular Senescence in Cancer and Aging: Relevance to Microorganisms2022

    • Author(s)
      Eiji Hara
    • Organizer
      EMBO Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] 細胞老化による発癌制御: 微生物の関与について2022

    • Author(s)
      原英二
    • Organizer
      日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Cellular Snescence and Cancer: A Gut Microbial Connection2022

    • Author(s)
      Eiji Hara
    • Organizer
      14th International Congress of Cell Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Cellular senescence and cancer : a gut microbial connection2022

    • Author(s)
      原英二
    • Organizer
      日本免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Cellular senescence and cancer: relevance to microorganisms2022

    • Author(s)
      原英二
    • Organizer
      日本癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00457
  • [Presentation] Involvement of oral flora in the colonic flora of colorecral cancer2020

    • Author(s)
      Uchino Yoshinori, Goto Yuichi, Kita Yoshiaki, Hara Eiji, Sugiura Tsuyoshi
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-19K10361
  • [Presentation] Obesity and cancer : a gut microbial connection2016

    • Author(s)
      Eiji Hara
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Obesity, the gut microbiome and liver cancer2016

    • Author(s)
      Eiji Hara
    • Organizer
      EASL The International Liver Congress
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2016-04-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Cellular senescence and liver cancer : a gut microbial connection2016

    • Author(s)
      Eiji Hara
    • Organizer
      FASEB Conference, Liver Biology
    • Place of Presentation
      West palm beach, FL, USA
    • Year and Date
      2016-06-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 腸内細菌による発がん制御2016

    • Author(s)
      原 英二
    • Organizer
      日本臨床栄養学会
    • Place of Presentation
      大阪市
    • Year and Date
      2016-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 細胞老化の発がん制御における役割2015

    • Author(s)
      原 英二
    • Organizer
      ヒューマンサイエンス総合研究セミナー
    • Place of Presentation
      東京
    • Year and Date
      2015-01-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] Obesity and cellular senescence: a gut microbial connection2015

    • Author(s)
      Eiji Hara
    • Organizer
      International Cell Senescence Association Conference
    • Place of Presentation
      Santiago de Compostela, Spain
    • Year and Date
      2015-07-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 細胞老化の発癌制御における役割2015

    • Author(s)
      原英二
    • Organizer
      ヒューマンサイエンス総合研究セミナー
    • Place of Presentation
      東京
    • Year and Date
      2015-01-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Obesity and Cellular Senescence: a gut microbial connection2015

    • Author(s)
      Eiji Hara
    • Organizer
      EMBO Workshop Developmental Circuits in Aging
    • Place of Presentation
      Crete, Greece
    • Year and Date
      2015-05-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 肥満と肝がん:腸内細菌の関与について2015

    • Author(s)
      原英二
    • Organizer
      泌尿器科分子細胞研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-02-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretom.2014

    • Author(s)
      Eiji Hara
    • Organizer
      US-Japan Joint Meeting on Biomarkers for Early Cancer Detection.
    • Place of Presentation
      Gaithersburg (USA)
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] 細胞老化と発がん2014

    • Author(s)
      原英二
    • Organizer
      日本臨床分子医学会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretom2014

    • Author(s)
      Hara, E
    • Organizer
      US-Japan Joint Meeting on Biomarkers for Early Cancer Detection
    • Place of Presentation
      Gaithersburg (USA)
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] 細胞老化による発がん制御2014

    • Author(s)
      原 英二
    • Organizer
      肺リモデリング研究会
    • Place of Presentation
      東京
    • Year and Date
      2014-11-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] DNA damage response and cellular senescence in cancer2013

    • Author(s)
      Eiji Hara
    • Organizer
      9th AACR-JCA joint conference
    • Place of Presentation
      Hyatt Regency Maui (米国、ハワイ)
    • Year and Date
      2013-02-21
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome2013

    • Author(s)
      Hara, E.
    • Organizer
      17th International Symposium on Cell of the Hepatic Sinusoid.
    • Place of Presentation
      大阪市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] DNA damage response and cellular senescence in cancer and aging.2013

    • Author(s)
      Eiji Hara
    • Organizer
      International Conference of the Korean Society for Molecular and Cellular Biology
    • Place of Presentation
      Seoul (South Korea)
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretom2013

    • Author(s)
      Hara, E
    • Organizer
      17th International Symposium on Cell of the Hepatic Sinusoid
    • Place of Presentation
      Osaka (Japan)
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] 細胞老化のがん化と老化における役割2013

    • Author(s)
      原 英二
    • Organizer
      日本生化学会 シンポジウム
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] DNA damage response and cellular senescence in cancer2013

    • Author(s)
      Hara, E.
    • Organizer
      9th AACR-JCA joint conference
    • Place of Presentation
      Maui, HI, (U.S.A.)
    • Year and Date
      2013-02-21
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] 細胞老化のがんと老化における役割2013

    • Author(s)
      原 英二
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome2013

    • Author(s)
      Eiji Hara
    • Organizer
      17th International Symposium on Cells of the Hepatic Sinusoid
    • Place of Presentation
      大阪国際会議場(大阪)
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] DNA damage response and cellular senescence in cancer and aging2013

    • Author(s)
      Hara, E
    • Organizer
      International Conference of the Korean Society for Molecular and Cellular Biology
    • Place of Presentation
      Seoul, (South Korea)
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] 細胞老化のがん化と廊下における役割2013

    • Author(s)
      原 英二
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Cellular senescence : a double-edged sword in the fight against cancer2012

    • Author(s)
      Hara, E
    • Organizer
      International Symposium on Clinical & Translational Cancer Research
    • Place of Presentation
      Kaoshun (Taiwan)
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] 細胞老化とがん2012

    • Author(s)
      原 英二
    • Organizer
      日本女性医学会
    • Place of Presentation
      山形市
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] Cellular senescence: a double-edged sword in the fight against cancer2012

    • Author(s)
      Hara, E.
    • Organizer
      International Symposium on Clinical Translational Cancer Research
    • Place of Presentation
      高雄市 (台湾)
    • Year and Date
      2012-05-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] The roles of cellular senescence in cancer and aging.2012

    • Author(s)
      Hara, E.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] 細胞老化とがん2012

    • Author(s)
      原 英二
    • Organizer
      日本女性医学会
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] 細胞老化の分子メカニズムとその生体内機能2012

    • Author(s)
      原 英二
    • Organizer
      日本生化学会関東支部会シンポジウム
    • Place of Presentation
      前橋市
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] The roles of cellular senescence in cancer and aging2012

    • Author(s)
      原 英二
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡市
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] The roles and mechanisms regulating cellular2012

    • Author(s)
      Hara, E.
    • Organizer
      日本癌学会
    • Place of Presentation
      札幌市
    • Year and Date
      2012-09-19
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Cellular senescence: a double-edged sword in the fight against cancer.2012

    • Author(s)
      Hara, E.
    • Organizer
      International Symposium on Clinical & Translational Cancer Research
    • Place of Presentation
      高雄市 (台湾)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] The roles of cellular senescence in cancer and aging.2012

    • Author(s)
      原 英二
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化の分子機構とその役割2011

    • Author(s)
      原英二
    • Organizer
      日本血管生物医学会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PUBLICLY-22019043
  • [Presentation] 細胞老化の分子機構とその役割2011

    • Author(s)
      原英二
    • Organizer
      日本血管生物医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] The roles and mechanisms regulating cellular senescence in aging and cancer2011

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-23300352
  • [Presentation] The roles and mechanisms regulating cellular senescence in aging and cancer2011

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] The roles and mechanisms regulating cellular senescence in aging and cancer2011

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜(招待講演)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PUBLICLY-22019043
  • [Presentation] 細胞老化の分子機構とその役割2011

    • Author(s)
      原英二
    • Organizer
      日本血管生物医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Intrinsic cooperation between p16^<INK4a> and p21^<Waf1/Cip1> in the onset of cellular senescence and tumor suppression in vivo.2010

    • Author(s)
      Takeuchi S., Takahashi A., Motoi N., Yoshimoto S., Tajima T., Yamakoshi K., Ishikawa Y., Sone S., Hara E., Ohtani N.
    • Organizer
      Cold Spring Harbor Laboratory Meeting : Molecular Genetics of Aging
    • Place of Presentation
      New York, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time in vivo imaging of p16^<Ink4a> reveals cross-talk with p53.2010

    • Author(s)
      原英二
    • Organizer
      IMCB symposium on cell cycle regulation and tumorigenesis.
    • Place of Presentation
      Singapore, Singapore
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] DNA damage dependent degradation of histone methyltransferase in cellular senescence.2010

    • Author(s)
      Takahashi A., Yamakoshi K., Imai Y., Ohtani N., Hara E
    • Organizer
      Cold Spring Harbor Laboratory Meeting : Molecular Genetics of Aging
    • Place of Presentation
      New York, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Backup tumor suppressor role for p16^<INK4a> in the event of p53 inactivation2010

    • Author(s)
      Takahashi A., Yamakoshi K., Ohtani N., Hara E
    • Organizer
      日本分子生物学会・日本生化学会合同年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] 蛍光・発光融合プローブを用いたOct4遺伝子イメージングシステムの開発2010

    • Author(s)
      田島丈子、杉田千鶴、近江谷克祐、中尾和貴、柳茂、深見希代子、原英二、大谷直子
    • Organizer
      日本分子生物学会・日本生化学会合同年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Cellular senescence: its role in tumor suppression and aging2010

    • Author(s)
      原英二
    • Organizer
      Asian aging core for longevity research
    • Place of Presentation
      Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] 癌増殖における線維素溶解系因子の役割と新規治療法の開発2010

    • Author(s)
      石原誠人、Beate Heissig, ほか
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際コンベンションセンター(大阪府大阪市)
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] Cellular senescence : its role in tumor suppression and aging2010

    • Author(s)
      Eiji Hara
    • Organizer
      Asian aging core for longevity research
    • Place of Presentation
      Jeju, South Korea
    • Year and Date
      2010-08-22
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] 細胞老化において発癌を促進する因子の探索2010

    • Author(s)
      今井良紀、高橋暁子、八尾良司、大谷直子、広田亨、田原栄俊、井出利憲、野田哲生、原英二
    • Organizer
      日本癌学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] 細胞老化の分子メカニズムとその役割2010

    • Author(s)
      原英二
    • Organizer
      日本炎症・再生医学会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2010-08-05
    • Data Source
      KAKENHI-PROJECT-21659083
  • [Presentation] 細胞老化の分子メカニズムとその役割2010

    • Author(s)
      原英二
    • Organizer
      日本炎症・再生医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time in vivo imaging of p16^<Ink4a> unveils a cross talk between p53 and p16^<Ink4a>2009

    • Author(s)
      Eiji Hara
    • Organizer
      IMCB Symposium on Cell Cycle Regulation & Tumorigenesis
    • Place of Presentation
      シンガポール シンガポール市
    • Data Source
      KAKENHI-PROJECT-21659083
  • [Presentation] Real-time in vivo imaging of p16Ink4a unveils a cross talk between p53 and p16Ink4a2009

    • Author(s)
      Eiji Hara
    • Organizer
      IMCB Symposium on Cell Cycle Regulation & Tumorigenesis
    • Place of Presentation
      シンガポール
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] Real-time in vivo imaging of p16^<Ink4a> unveils a cross talk between p53 and p16^<Ink4a>2009

    • Author(s)
      Eiji Hara
    • Organizer
      IMCB Symposium on Cell Cycle Regulation & Tumorigenesis
    • Place of Presentation
      シンガポールシンガポール市
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] Visualizing the dynamics of oncogenic stress response in living mice.2009

    • Author(s)
      Ohtani N., Yamakoshi K., Takahashi A., Hara E
    • Organizer
      AACR Conference on Mouse model of Cancer
    • Place of Presentation
      San Francisco, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time in vivo imaging of p16Ink4a unveils a cross talk between p53 and p16Ink4a2009

    • Author(s)
      Kimi Yamakoshi, Akiko Takahashi, Naoko Ohtani, Eiji Hara
    • Organizer
      The Salk Institute Meeting on Maechanisms and Models of Cancer
    • Place of Presentation
      ラホヤ、アメリカ
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] Real-time in vivo imaging of p16^<Ink4a> expression unveils a cross-talk between p53 and p16^<Ink4a>2009

    • Author(s)
      Yamakoshi K., Takahashi A., Ohtani N., Hara E
    • Organizer
      The Salk Institute Meeting /Mechanisms & Models of Cancer
    • Place of Presentation
      La Jolla, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time in vivo imaging of p16^<Ink4a> unveils a cross talk between p53 and p16^<Ink4a>2009

    • Author(s)
      Eiji Hara
    • Organizer
      IMCB Symposium on Cell Cycle Regulation & Tumorigenesis
    • Place of Presentation
      シンガポール シンガポール市
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time imaging of p16^<INK4a> expression visualizes the dynamics of senescence signaling in living mice2008

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会・日本生化学会合同大会
    • Place of Presentation
      神戸市ポートアイランド
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20659049
  • [Presentation] Real-time imaging of p16^<1NK4a> expression visualizes the dynamics of senescence slgnaling in living mice.2008

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会・日本生化学会合同大会
    • Place of Presentation
      神戸市ポートアイランド
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] Real-time imaging of p16^<INK4a> expression visualizes the dynamics of senescence signaling in living mice2008

    • Author(s)
      Eiji Hara
    • Organizer
      日本分子生物学会・日本生化学会合同大会
    • Place of Presentation
      神戸市ポートアイランド
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time imaging of p16^<INK4a> expression visualizes the dynamics of senescence signalling in living animals.2008

    • Author(s)
      Yamakoshi K., Takahashi A., Ohtani N., Hara E
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390094
  • [Presentation] Real-time in vivo imaging of p16 tumor suppressor gene expression2007

    • Author(s)
      原 英二
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] The role of p16Ink4a CDK inhibitor in cell cycle control and cellular senescence.2007

    • Author(s)
      Eiji Hara
    • Organizer
      Gene & Cancer Meeting
    • Place of Presentation
      ウォーリック、イギリス
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] Mitogenic signaling and p16/Rb-pathway cooperate to enforce irreversible cellular senescence through activating ROS/PKC-δ signaling pathway2007

    • Author(s)
      Akiko Takahashi, Naoko Ohtani, Kimi Yamakoshi, Eiji Hara
    • Organizer
      Keystone Symposium
    • Place of Presentation
      ウィスラー、カナダ
    • Data Source
      KAKENHI-PROJECT-17013064
  • [Presentation] The role of p16 CDK inhibitor in cell cycle control and senescence2007

    • Author(s)
      Eiji Hara
    • Organizer
      Genes&Cancer 24^<th> Meeting
    • Place of Presentation
      イギリス・Warwick市
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18370080
  • [Presentation] The role of p16 CDK inhibitor in cell cycle control and senescence.2007

    • Author(s)
      Eiji Hara
    • Organizer
      Genes&Cancer 24th Meeting
    • Place of Presentation
      イギリス・Warwick市
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18370080
  • [Presentation] The role of p16 CDK inhibitor in cell cycle control and senescence2007

    • Author(s)
      Eiji, Hara
    • Organizer
      Genes & Cancer 24th Meeting, December 12th
    • Place of Presentation
      Warwick, UK
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18370080
  • [Presentation] 細胞老化反応の生体内イメージング

    • Author(s)
      大熊敦史、大谷直子、山越貴水、原 英二
    • Organizer
      日本生化学会
    • Place of Presentation
      京都市
    • Year and Date
      2014-10-15 – 2014-10-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Relationship between obesity, gut microbiome and HCC development

    • Author(s)
      Eiji Hara
    • Organizer
      Falk Gastro-Conference
    • Place of Presentation
      Freiburg, Germany
    • Year and Date
      2014-10-08 – 2014-10-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Obesity and cancer: a gut microbial connection

    • Author(s)
      Eiji Hara
    • Organizer
      日本免疫学会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-10 – 2014-12-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] 細胞老化と発がん:腸内細菌の関与について

    • Author(s)
      原英二
    • Organizer
      日本肥満学会
    • Place of Presentation
      宮崎
    • Year and Date
      2014-10-23 – 2014-10-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Gut microbiota and fatty liver disease

    • Author(s)
      Eiji Hara
    • Organizer
      Gut microbiota for health world summit 2015
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2015-03-14 – 2015-03-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer via senescence secretome

    • Author(s)
      Eiji Hara
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2014-05-19 – 2014-05-23
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] The roles and mechanisms of cellular senescence

    • Author(s)
      Eiji Hara
    • Organizer
      日本基礎老化学会
    • Place of Presentation
      大府
    • Year and Date
      2014-06-26 – 2014-06-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Cross-talk between the Rb^pathway and AKT signaling forms a quiescence-senescence switch

    • Author(s)
      Eiji Hara
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Cellular senescence and cancer: a gut microbial connection

    • Author(s)
      Eiji Hara
    • Organizer
      Joint international symposium on TGF-b family and cancer signal network in tumor microenvironment
    • Place of Presentation
      つくば
    • Year and Date
      2015-01-12 – 2015-01-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] 細胞老化と炎症

    • Author(s)
      原 英二
    • Organizer
      日本炎症・再生医学会
    • Place of Presentation
      沖縄県名護市
    • Year and Date
      2014-07-01 – 2014-07-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] TGF-β signaling inhibitor eradicates chronic myelogenous leukemia stem cells

    • Author(s)
      仲 一仁、石原薫理、定免由枝
    • Organizer
      がん研究分野の特性等を踏まえた支援活動・公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都千代田区)
    • Year and Date
      2015-01-27 – 2015-01-28
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] 細胞老化と炎症

    • Author(s)
      原 英二
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-10 – 2014-07-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化反応の生体内イメージング

    • Author(s)
      大熊敦史、大谷直子、山越貴水、原 英二
    • Organizer
      日本生化学会シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化と炎症

    • Author(s)
      原英二
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-10 – 2014-07-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] Gut microbiota and fatty liver disease

    • Author(s)
      Eiji Hara
    • Organizer
      Gut microbiota for health world summit 2015
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2015-03-14 – 2015-03-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 細胞老化と発癌:腸内細菌の関与について

    • Author(s)
      原英二
    • Organizer
      日本肥満学会
    • Place of Presentation
      宮崎市
    • Year and Date
      2014-10-23 – 2014-10-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Relationship between obesity, gut microbiome and HCC development

    • Author(s)
      Eiji Hara
    • Organizer
      Falk Gastro-Conference
    • Place of Presentation
      Freiburg, Germany
    • Year and Date
      2014-10-08 – 2014-10-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Obesity and cancer: a gut microbial connection

    • Author(s)
      Eiji Hara
    • Organizer
      日本免疫学会
    • Place of Presentation
      京都市
    • Year and Date
      2014-12-10 – 2014-12-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 肥満と肝がん:腸内細菌の関与について

    • Author(s)
      原英二
    • Organizer
      酸化ストレスと肝研究会
    • Place of Presentation
      福岡
    • Year and Date
      2015-02-14 – 2015-02-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] The roles of cellular senescence in aging and cancer

    • Author(s)
      Akiko Takahashi, Eiji Hara
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-11-25 – 2014-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Obesity-induced gut microbial metabolite promotes liver cancer via senescence secretome

    • Author(s)
      Eiji Hara
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2014-05-19 – 2014-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] The roles and mechanisms of cellular senescence

    • Author(s)
      Eiji Hara
    • Organizer
      日本基礎老化学会国際シンポジウム
    • Place of Presentation
      愛知県大府市
    • Year and Date
      2014-06-26 – 2014-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化と炎症

    • Author(s)
      原 英二
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-11 – 2014-07-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] 細胞老化と発癌

    • Author(s)
      原 英二
    • Organizer
      日本臨床分子医学会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-12 – 2014-04-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] The roles of cellular senescence in aging and cancer

    • Author(s)
      Akiko Takahashi & Eiji Hara
    • Organizer
      日本分子生物学会シンポジウム
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-11-25 – 2014-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化と炎症

    • Author(s)
      原 英二
    • Organizer
      炎症・再生医学会シンポジウム
    • Place of Presentation
      沖縄県名護市
    • Year and Date
      2014-07-01 – 2014-07-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化と炎症

    • Author(s)
      原英二
    • Organizer
      日本炎症再生医学会
    • Place of Presentation
      名護
    • Year and Date
      2014-07-01 – 2014-07-03
    • Invited
    • Data Source
      KAKENHI-PLANNED-23112101
  • [Presentation] 細胞老化と発癌

    • Author(s)
      原 英二
    • Organizer
      日本臨床分子医学会 シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-04-12 – 2014-04-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] 細胞老化と癌:細胞老化の功罪

    • Author(s)
      原 英二
    • Organizer
      高遠・分子細胞生物学シンポジウム
    • Place of Presentation
      長野県伊那市
    • Year and Date
      2014-08-28 – 2014-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • [Presentation] Crosstalk between the Rb-pathway and AKT signaling forms a Quiescence- Senescence switch

    • Author(s)
      Eiji Hara
    • Organizer
      日本癌学会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] The roles and mechanisms of cellular senescence

    • Author(s)
      Eiji Hara
    • Organizer
      日本基礎老化学会国際シンポジウム
    • Place of Presentation
      愛知県大府市
    • Year and Date
      2014-06-26 – 2014-06-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250028
  • [Presentation] Crosstalk between the Rb-pathway and AKT signaling forms a Quiescence- Senescence switch

    • Author(s)
      Eiji Hara
    • Organizer
      日本癌学会コアシンポジウム
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650625
  • 1.  NAKAMURA Toshikazu (00049397)
    # of Collaborated Projects: 2 results
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  • 2.  KOSHIMIZU Uichi (50281126)
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    # of Collaborated Projects: 1 results
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  • 19.  KUBO Yoshiaki (10260069)
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  • 20.  Goto Yuichi (00637902)
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  • 23.  水野 健作 (70128396)
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  • 24.  盛 真一郎 (00620519)
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  • 25.  井戸 章雄 (30291545)
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  • 26.  喜多 芳昭 (30570692)
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  • 27.  杉浦 剛 (40322292)
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  • 30.  夏越 祥次 (70237577)
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  • 37.  有田 誠
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  • 38.  有田 正規
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  • 39.  杉本 幸彦
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