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Okazaki Yasushi  岡崎 康司

ORCIDConnect your ORCID iD *help
… Alternative Names

OKAZAKI Yasushi  岡崎 康司

OKAZAKI YASUSHI  岡﨑 康司

OKAZAKI Yasuji  岡崎 康司

岡崎 康司  オカザキ ヤスシ

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Researcher Number 80280733
Other IDs
External Links
Affiliation (Current) 2025: 順天堂大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 順天堂大学, 大学院医学研究科, 教授
2021 – 2024: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー
2018 – 2021: 順天堂大学, 医学(系)研究科(研究院), 教授
2017: 埼玉医科大学, 医学部, 客員教授
2007 – 2017: 埼玉医科大学, 医学部, 教授 … More
2015: 埼玉医科大, 医学部, 教授
2004: 埼玉医科大学, 医学部, 教授
2003: Saitama Medical University, Genome Research Center, Professor
2000 – 2003: 理化学研究所, ゲノム科学総合研究センター, チームリーダー
2002: 横浜市立大学, 医学部, 助教授
2002: Rlken Institute, Team Leader, 理化学研究所, チームリーダー
2002: 理化学研究所, (研究職), チームリーダー
2002: The Institute of physical and chemical Research, Genomic Sciences center, ゲノム科学総合センター・遺伝子構造・機能研究グループ, チームリーダー
2002: 理化学研究所, ゲノム科学総合研究センター(研究職), チームリーダー
2002: 理化学研究所, ゲノム科学総合研究センター, 研究職チームリーダー
2001: 理化学研究所, チームリーダー
2001: 理化学研究所, ゲノム科学総合センター, 遺伝子構造・機能研究グループチームリーダー
2001: 理化学研究所, ゲノム科学総合研究センター, チームリーダ
2000 – 2001: 理化学研究所, 横浜研究所・ゲノム科学総合研究センター, 専任研究員
2000: 理化学研究所, ゲノム科学総合研究センター, チームリーダー(研究職)
2000: 理化学研究所, ゲノム科学総合研究センター, 研究職チームリーダー
1996: 理化学研究所, ゲノム科学研究室, 研究員 Less
Review Section/Research Field
Principal Investigator
Medium-sized Section 52:General internal medicine and related fields / Pathological medical chemistry / Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Regenerative medicine / Pathological medical chemistry / Biological Sciences
Except Principal Investigator
Digestive surgery / Endocrinology / Metabolomics … More / Biological Sciences / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52010:General internal medicine-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering / Pediatrics / Surgical dentistry / Psychiatric science / Orthopaedic surgery / Medical pharmacy / Applied pharmacology Less
Keywords
Principal Investigator
ミトコンドリア病 / ヘテロプラスミー / シングルセル / マルチオミックス解析 / ヘテロプラスミー率 / ゲノム解析 / 心筋症 / シングルセル解析 / メタボローム解析 / ミトコンドリアDNA … More / オミックス解析 / Molecular biology / Human genetics / Mitochondria / マルチオミクス / RNAシーケンス / プロテオーム / 全ゲノム解析 / 全エクソーム解析 / ミトコンドリア内RNA / マイクロRNA / 呼吸鎖酵素 / 非コードRNA / ミトコンドリア / noncoding RNA / mitochondria / 化合物スクリーニング / 膵β細胞 / iPS細胞 / double KI hiPSC / single cell / β細胞 / ケミカルスクリーニング / hiPSレポーター / 膵β細胞分化 / Tysndl / 脂肪酸β-酸化 / 雄性不妊 / フィタン酸 / プラスマローゲン / 超長鎖脂肪酸 / 脂肪酸ss-酸化 / プロテアーゼ / ペルオキシソーム / Tysnd1 / マイクロアレイ / 遺伝子 / 遺伝学 / 脂質 / ゲノム / δ-sarcoglycan / sarcoglycanopathy / BIO14.6 / cardio myopathy … More
Except Principal Investigator
糖尿病 / cDNA microarray / シングルセル解析 / DNAマイクロアレイ / DNAメチル化 / BCL-2 / 急性骨髄性白血病 / 全エクソーム解析 / 分化 / エピジェネティクス / 骨芽細胞 / 破骨細胞 / 骨代謝 / apoptosis / cDNAmicroarray / 消化管ホルモン / プレコンディショニング / cDNAマイクロアレイ / 腫瘍内不均一性 / 薬剤耐性 / 胸部悪性腫瘍 / 内在性レトロウイルス / 高齢者 / 白血病幹細胞 / バイオマーカー / Single-Cell ATAC-Seq / DNAメチル基転移酵素 / 難治性白血病 / RNA-seq / single cell ATAC-seq / single cell RNA-seq / RNA-seq解析 / メチル化アレイ解析 / BCL-2阻害剤 / 骨髄微小環境 / インターフェロン誘導遺伝子 / DNAメチル化阻害剤 / BCL-2 阻害剤 / 細胞分化 / 直接変換 / RNA送達 / RNA / 直接分化転換 / ダイレクトリプログラミング / 体細胞 / インスリン / 1型糖尿病 / 分化転換 / hiPSダブルノックイン / β細胞 / single cell / hiPS / single cell analysis / beta cell / 網羅的行動解析 / Tysnd1 / 脂質代謝 / 自閉症スペクトラム / 小脳 / 歯状回 / プラスマローゲン / 脂質代謝異常 / 自閉症 / ペルオキシソーム / 神経系 / 血管系 / CDK6 / 分化能 / 遊走能 / 遺伝子網羅的解析 / ネットワーク / 神経芽細胞 / ネットワーク機構 / 骨減少症 / 骨・神経・血管 / 血管内皮細胞 / 骨細胞 / semaphorin 3A / netrin-4 / 変異・多型 / 全ゲノム解析 / 性別違和 / 性同一性障害 / 次世代シーケンス / 感受性 / エクソーム解析 / 自然免疫 / 遺伝 / 日本人 / 疾患感受性 / 多型 / 変異 / SNP / バリアント / トール様受容体 / 2型糖尿病 / 疾患感受性遺伝子 / 1型糖尿病 / 膵β細胞 / 遺伝子調節 / Pax6 / ロコモティブ / 転写因子 / エピジェネティック / 糖代謝 / Mouse / cDNA Microarrav / Hepatic Failure / Hepatectomy / マウス / 肝不全 / 肝切除 / gastric cancer / dissemination / peritoneal / DNAチップ / 腹膜播種性転移 / 胃癌 / Apoptosis / Preconditioning / Heat-shock protein / Prostaglandin E_1 / Ischemia-reperfusion injury of the liver / 熱ショック蛋白 / Heat shock Protein / 肝虚血再灌流障害 / アポトーシス / Heat Shock Protein / Prostaglandin E1 / 肝虚血再灌流生涯 / Liver regeneration / cDNA Microarray / postoperative liver failure / cDNA microarra / hepatectomy / liver regeneration / liver failure / Carcinogenesis / cDNA / Micro array / Pancreaticobiliary maljunction / 膵胆管合流異常 / マイクロアレイ / 膵胆管合流異常症 / Preoperative diagnosis of the lymph node metastasis for the gastric cancer / DNA micro array / 胃癌リンパ節転移 / 胃癌リンパ節診断 / date analysis / gene expression profile / colon cancer / cDNA micro array / 遺伝子 / データ解析 / 遺伝子発現 / 大腸癌 / 抗癌性耐性 / 担癌剤耐性 / 抗癌剤耐性 / UGT1A1 / トランスポーター / 体内動態 / イリノテカン / 腎不全 / 尿毒症物質 / 腎機能 / 排出遅延 / 肝消失型 / 蛋白結合 / 肝消失型抗がん薬 / 発現低下 / OATP1B1 / 尿毒素 / 腎機能低下 / 排泄遅延 / SN-38 / 新規分泌タンパク / 薬力 / 薬物動態 / 緩和医療 / がん疼痛 / UGT2B7 / OPRM1 / ABCB1 / 薬物有害反応 / 薬理遺伝学 / モルヒネ / 遺伝子発現データベース / ischemic preconditioning / 虚血、再潅流傷害 / 虚血、再潅流障害 Less
  • Research Projects

    (34 results)
  • Research Products

    (141 results)
  • Co-Researchers

    (79 People)
  •  Establishment of multi-layered omics analysis for mitochondrial disease patientsPrincipal Investigator

    • Principal Investigator
      岡崎 康司
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Juntendo University
  •  薬剤耐性クローンに着目した腫瘍内不均一性と薬剤耐性原理の解明

    • Principal Investigator
      田島 健
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Juntendo University
  •  難治性白血病の内在性レトロウイルス活性化機序に基づく新規バイオマーカー開発

    • Principal Investigator
      田部 陽子
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Juntendo University
  •  Development of RNA therapies for curing of type 1 diabetes

    • Principal Investigator
      Matsumto Masahito
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Juntendo University
      Tokyo Medical and Dental University
  •  Comprehensive analysis of of aberrant gene expression in mitochondrial disordersPrincipal Investigator

    • Principal Investigator
      OkazakiOkazaki Yasushi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Juntendo University
  •  Leukemic stem cell signatures to identify therapeutic targets of elderly acute myeloid leukemia

    • Principal Investigator
      田部 陽子
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Juntendo University
  •  Genetic analysis and investigation of molecular pathogenesis for mitochondrial diseasesPrincipal Investigator

    • Principal Investigator
      岡崎 康司
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Juntendo University
      Saitama Medical University
  •  Novel mechanisms of mitochondria diseases caused by mitochondrial noncoding RNAsPrincipal Investigator

    • Principal Investigator
      Yasushi Okazaki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Saitama Medical University
  •  Development of biomarker related to gender dysphoria (gender identity disorder) based on whole exome sequencing analysis.

    • Principal Investigator
      NAKACHI Yutaka
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      Saitama Medical University
  •  Development and finding the mechanism of pancreatic beta cell differentiation from hiPS cells through Single cell analysis

    • Principal Investigator
      Sugahara Izumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      National Center for Global Health and Medicine
      Saitama Medical University
  •  Elucidation of pancreatic beta-cell proliferation and differentiation mechanism by novel intestinal secretory protein IBCAP (betagenin).

    • Principal Investigator
      Yokoo Tomotaka
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Endocrinology
    • Research Institution
      Saitama Medical University
  •  Identification of susceptibility variants to type 1 diabetes using whole-exome sequencing

    • Principal Investigator
      Awata Takuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      International University of Health and Welfare
      Saitama Medical University
  •  Molecular mechanisms of nerve-vessel-bone network

    • Principal Investigator
      SATO Tsuyoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Saitama Medical University
  •  Fundamental study for clinical application of autistic spectrum with peroxisome lipid metabolism abnormality

    • Principal Investigator
      Mizuno Yumi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Saitama Medical University
  •  Chemical screening of novel factor to promote beta cell differentiation from hiPS cellsPrincipal Investigator

    • Principal Investigator
      Okazaki Yasushi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Regenerative medicine
    • Research Institution
      Saitama Medical University
  •  The analysis of the novel intestinal hormone, IBCAP (Betagenin) in the pancreatic beta-cells functions.

    • Principal Investigator
      Toyoshima Hideo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Saitama Medical University
  •  Molecular insights of the crosstalk between locomotive and metabolic syndromes

    • Principal Investigator
      Matsumoto Masahito
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
  •  Application of the novel intestinal hormone, IBCAP targeted pancreas beta-cell regeneration therapy.

    • Principal Investigator
      YOKOO TOMOTAKA
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Endocrinology
    • Research Institution
      Saitama Medical University
  •  Mechanism for the delayed elimination of SN-38 in cancer patients with severe renal failure and optimal treatment strategy

    • Principal Investigator
      FUJITA Ken-ichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Showa University
      Saitama Medical University
  •  Functional analysis of the novel intestinal hormone, IBCAP withincretin-like activity

    • Principal Investigator
      TOYOSHIMA Hideo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Saitama Medical University
  •  Functional analysis of Tysnd1 and its pathogenic mechanismPrincipal Investigator

    • Principal Investigator
      OKAZAKI Yasushi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Saitama Medical University
  •  Factors causing interindividual variability in response to morphine

    • Principal Investigator
      FUJITA Ken-ichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Saitama Medical University
  •  遺伝学とトランスクリプトームの統合による高脂血症の遺伝子ネットワークの解明Principal Investigator

    • Principal Investigator
      岡崎 康司
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Saitama Medical University
  •  Analysis of gene expression profiles in partial hepatectomized mice using cDNA microarray

    • Principal Investigator
      TANAKA Kuniya
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Yokohama City University
  •  cDNAマイクロアレイを用いた臓器虚血障害、再潅流障害における遺伝子発現の解明

    • Principal Investigator
      里見 進
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  THE MECHANISM OF LIVER FAILURE AFTER EXCESSIVE HEPATECTOMY INVESTIGATED USING CDAN MICROARRAY

    • Principal Investigator
      TOGO Shinji
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Yokohama City University
  •  Analysis of mechanisims of the ischemia-reperfusion injury of the liver using cDNA microarray

    • Principal Investigator
      MIURA Yasuhiko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Yokohama City University
  •  Analysis of differential gene expression profiles of gastric cancer cells established from primary tumor and malignant ascites

    • Principal Investigator
      SQAKAKURA Chouhei
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  DNAマイクロアレイを用いた臓器虚血障害、再潅流障害における遺伝子発現の解明

    • Principal Investigator
      里見 進
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Analysis using DNA chip for responder, and non-responder in patients with advanced esophageal cancer

    • Principal Investigator
      KUNISAKI Chikara
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Yokohama City University
  •  I densification of genes regulating colorectal carcwageuesis by using the algorithm for disguising malignant state method

    • Principal Investigator
      ISHIKAWA Takashi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Yokohama City University
  •  The preoperative diagnosis of the lymph node metastasis for the gastric cancer used by the DNA micro array

    • Principal Investigator
      AKIYAMA Hirotoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Yokohama city university
  •  MECHANISM OF CAR CINOGENESIS IN THE BILIATY SYSTEM-MOLECULAR BIOLOGICAL ANALYSIS OF PANCREATICOBILIARY MALJUNCTION USING CDNA MICROARRAY

    • Principal Investigator
      SEKIDO Hitoshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      YOKOHAMA CITY UNIVERSITY, SCHOOL OF MECICINE
  •  心筋症ハムスターの原因遺伝子探索Principal Investigator

    • Principal Investigator
      岡崎 康司
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

  • [Book] バイオテクノロジーの温故知新「DNAマイクロアレイ-ゲノムワイド解析の道を開いた技術革新」実験医学2012

    • Author(s)
      岡崎康司
    • Total Pages
      5
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Book] 実験医学;バイオテクノロジーの温故知新「DNAマイクロアレイーゲノムワイド解析の道を開いた技術革新」2012

    • Author(s)
      岡崎康司, 他
    • Total Pages
      5
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Book] 医学の歩み;骨粗鬆症の遺伝子ネットワーク2011

    • Author(s)
      岡崎康司, 他
    • Total Pages
      6
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Book] 骨粗鬆症の遺伝子ネットワーク医学のあゆみ医歯薬2011

    • Author(s)
      徳澤佳美, 岡崎康司
    • Total Pages
      6
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Journal Article] Identification of a novel MT-ND3 variant and restoring mitochondrial function by allotopic expression of MT-ND3 gene2024

    • Author(s)
      Borna Nurun Nahar、Kishita Yoshihito、Shimura Masaru、Murayama Kei、Ohtake Akira、Okazaki Yasushi
    • Journal Title

      Mitochondrion

      Volume: 76 Pages: 101858-101858

    • DOI

      10.1016/j.mito.2024.101858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Journal Article] ミトコンドリア病の遺伝子診断と病態解析2023

    • Author(s)
      杉山洋平, 八塚由紀子, 村山圭, 岡﨑康司
    • Journal Title

      実験医学増刊

      Volume: 41 Pages: 706-712

    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Journal Article] Antibody Deficiency in Patients with Biallelic KARS1 Mutations2023

    • Author(s)
      1.Saettini F, Guerra F, Fazio G, Bugarin C, McMillan JH, Ohtake A, Ardissone A, Itoh M, Giglio S, Cappuccio G, Giardino G, Romano R, Quadri M, Gasperini S, Moratto D, Chiarini M, Ishiguro A, Fukuhara Y, Hayakawa I, Okazaki Y, Mauri M, Piazza R, Cazzaniga G, Biondi A.
    • Journal Title

      J Clin Immunol.

      Volume: 2023Nov;43(8) Issue: 8 Pages: 2115-2125

    • DOI

      10.1007/s10875-023-01584-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07304, KAKENHI-PROJECT-23H00424
  • [Journal Article] ミトコンドリア病の病態解明と治療法の開発2023

    • Author(s)
      八塚由紀子、岡﨑康司
    • Journal Title

      生体の科学

      Volume: 74 Pages: 410-411

    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Journal Article] Focal segmental glomerulosclerosis with a mutation in the mitochondrially encoded NADH dehydrogenase 5 gene: A case report2023

    • Author(s)
      Naganuma Tsukasa、Imasawa Toshiyuki、Nukui Ikuo、Wakasugi Masakiyo、Kitamura Hiroshi、Yatsuka Yukiko、Kishita Yoshihito、Okazaki Yasushi、Murayama Kei、Jinguji Yoshimi
    • Journal Title

      Molecular Genetics and Metabolism Reports

      Volume: 35 Pages: 100963-100963

    • DOI

      10.1016/j.ymgmr.2023.100963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Journal Article] Strategic validation of variants of uncertain significance in ECHS1 genetic testing2023

    • Author(s)
      Yoshihito Kishita, Ayumu Sugiura, Takanori Onuki, Tomohiro Ebihara, Tetsuro Matsuhashi, Masaru Shimura, Takuya Fushimi, Noriko Ichino, Yoshie Nagatakidani, Hitomi Nishihata, Kazuhiro R Nitta, Yukiko Yatsuka, Atsuko Imai-Okazaki, Yibo Wu, Hitoshi Osaka, Akira Ohtake, Kei Murayama, Yasushi Okazaki
    • Journal Title

      Journal of Medical Genetics

      Volume: Online ahead of print Issue: 10 Pages: 1006-1015

    • DOI

      10.1136/jmg-2022-109027

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15950, KAKENHI-PROJECT-23K07236, KAKENHI-PROJECT-23K07488, KAKENHI-PROJECT-23H00424
  • [Journal Article] Clinical implementation of RNA sequencing for Mendelian disease diagnostics2022

    • Author(s)
      Yepez VA, Gusic M, Kopajtich R, Mertes C, Smith NH, Alston CL, Ban R, Beblo S, Berutti R, Blessing H, Ciara E, Distelmaier F, Freisinger P, Haberle J, Hayflick SJ, Hempel M, Itkis YS, Kishita Y et al.
    • Journal Title

      Genome Medicine

      Volume: 14 Issue: 1 Pages: 38-38

    • DOI

      10.1186/s13073-022-01019-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05519, KAKENHI-PROJECT-19H03624
  • [Journal Article] Development of Leigh syndrome with a high probability of cardiac manifestations in infantile-onset patients with m.14453G?>?A2022

    • Author(s)
      Shimura M, Onuki T, Sugiyama Y, Matsuhashi T, Ebihara T, Fushimi T, Tajika M, Ichimoto K, Matsunaga A, Tsuruoka T, Nitta KR, Imai-Okazaki A, Yatsuka Y, Kishita Y, Ohtake A, Okazaki Y, Murayama K.
    • Journal Title

      Mitochondrion

      Volume: 63 Pages: 1-8

    • DOI

      10.1016/j.mito.2021.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-20K08497
  • [Journal Article] Neonatal-onset mitochondrial disease: clinical features, molecular diagnosis and prognosis2021

    • Author(s)
      Ebihara T, Nagatomo T, Sugiyama Y, Tsuruoka T, Osone Y, Shimura M, Tajika M, Matsuhashi T, Ichimoto K, Matsunaga A, Akiyama N, Ogawa-Tominaga M, Yatsuka Y, Nitta KR, Kishita Y, Fushimi T, Imai-Okazaki A, Ohtake A, Okazaki Y, Murayama K.
    • Journal Title

      Archives of Disease in Childhood - Fetal and Neonatal Edition

      Volume: 107 Issue: 3 Pages: 329-334

    • DOI

      10.1136/archdischild-2021-321633

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-20H05519, KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-20K08497
  • [Journal Article] Long-term prognosis and genetic background of cardiomyopathy in 223 pediatric mitochondrial disease patients.2021

    • Author(s)
      Imai-Okazaki A, Matsunaga A, Yatsuka Y, Nitta KR, Kishita Y, Sugiura A, Sugiyama Y, Fushimi T, Shimura M, Ichimoto K, Tajika M, Tominaga M, Ebihara T, Matsuhashi T, Tsuruoka T, Kohda M, Hirata T, Harashima H, Nojiri S, Takeda A, Nakaya A, Kogaki S, Sakata Y, Ohtake A, Murayama K, Okazaki Y.
    • Journal Title

      International Journal of Cardiology

      Volume: 341 Pages: 48-55

    • DOI

      10.1016/j.ijcard.2021.06.042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08529, KAKENHI-PUBLICLY-20H05519, KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-20K08497
  • [Journal Article] Fatal Perinatal Mitochondrial Cardiac Failure Caused by Recurrent De Novo Duplications in the ATAD3 Locus2021

    • Author(s)
      Frazier Ann E.、Compton Alison G.、Kishita Yoshihito、Imai-Okazaki Atsuko、Nitta Kazuhiro R.、Ohtake Akira、Murayama Kei、Ryan Michael T.、Okazaki Yasushi、Stroud David A.、Simons Cas、Christodoulou John、Thorburn David R, et al.
    • Journal Title

      Med

      Volume: 2 Issue: 1 Pages: 49-73.e10

    • DOI

      10.1016/j.medj.2020.06.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05519, KAKENHI-PROJECT-19H03624
  • [Journal Article] Genome sequencing and RNA-seq analyses of mitochondrial complex I deficiency revealed Alu insertion-mediated deletion in NDUFV2.2021

    • Author(s)
      Kishita Y, Shimura M, Kohda M, Fushimi T, Nitta KR, Yatsuka Y, Hirose S, Ideguchi H, Ohtake A, Murayama K, Okazaki Y.
    • Journal Title

      Human Mutation

      Volume: 42 Issue: 11 Pages: 1422-1428

    • DOI

      10.1002/humu.24274

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-20H05519, KAKENHI-PROJECT-19H03624
  • [Journal Article] Valine metabolites analysis in ECHS1 deficiency2021

    • Author(s)
      Kuwajima M, Kojima K, Osaka H, Hamada Y, Jimbo E, Watanabe M, Aoki S, Sato-Shirai I, Ichimoto K, Fushimi T, Murayama K, Ohtake A, Kohda M, Kishita Y, Yatsuka Y, Uchino S, Mimaki M, Miyake N, Matsumoto N, Okazaki Y, Ogata T, Yamagata T, Muramatsu K.
    • Journal Title

      Molecular Genetics and Metabolism Reports

      Volume: 29 Pages: 100809-100809

    • DOI

      10.1016/j.ymgmr.2021.100809

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-19K08258, KAKENHI-PROJECT-21K07807, KAKENHI-PROJECT-20H03648
  • [Journal Article] A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome2021

    • Author(s)
      Kishita Yoshihito、Ishikawa Kaori、Nakada Kazuto、Hayashi Jun-Ichi、Fushimi Takuya、Shimura Masaru、Kohda Masakazu、Ohtake Akira、Murayama Kei、Okazaki Yasushi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 11123-11123

    • DOI

      10.1038/s41598-021-90196-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H00225, KAKENHI-PROJECT-19H03141, KAKENHI-PROJECT-19H03624
  • [Journal Article] A novel homozygous variant in MICOS13 / QIL1 causes hepato‐encephalopathy with mitochondrial DNA depletion syndrome2020

    • Author(s)
      Kishita Yoshihito、Shimura Masaru、Kohda Masakazu、Akita Masumi、Imai‐Okazaki Atsuko、Yatsuka Yukiko、Nakajima Yoko、Ito Tetsuya、Ohtake Akira、Murayama Kei、Okazaki Yasushi
    • Journal Title

      Molecular Genetics & Genomic Medicine

      Volume: 8 Issue: 10

    • DOI

      10.1002/mgg3.1427

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Journal Article] Early infantile-onset Leigh syndrome complicated with infantile spasms associated with the m.9185?T?>?C variant in the MT-ATP6 gene: Expanding the clinical spectrum2020

    • Author(s)
      Takada Rei、Tozawa Takenori、Kondo Hidehito、Kizaki Zenro、Kishita Yoshihito、Okazaki Yasushi、Murayama Kei、Ohtake Akira、Chiyonobu Tomohiro
    • Journal Title

      Brain and Development

      Volume: 42 Issue: 1 Pages: 69-72

    • DOI

      10.1016/j.braindev.2019.08.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-18K15724
  • [Journal Article] A homozygous variant in NDUFA8 is associated with developmental delay, microcephaly, and epilepsy due to mitochondrial complex I deficiency2020

    • Author(s)
      Yatsuka Yukiko、Kishita Yoshihito、Formosa Luke E.、Shimura Masaru、Nozaki Fumihito、Fujii Tatsuya、Nitta Kazuhiro R.、Ohtake Akira、Murayama Kei、Ryan Michael T.、Okazaki Yasushi
    • Journal Title

      Clinical Genetics

      Volume: 98 Issue: 2 Pages: 155-165

    • DOI

      10.1111/cge.13773

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Journal Article] Mortality of Japanese Patients With Leigh Syndrome: Effects of Age at Onset and Genetic Diagnosis2020

    • Author(s)
      Ogawa E, Fushimi T, Ogawa-Tominaga M, Shimura M, Tajika M, Ichimoto K, Matsunaga A, Tsuruoka T, Ishige M, Fuchigami T, Yamazaki T, Kishita Y, Kohda M, Imai-Okazaki A, Okazaki Y, Morioka I, Ohtake A, Murayama K.
    • Journal Title

      J Inherit Metab Dis

      Volume: - Issue: 4 Pages: 819-826

    • DOI

      10.1002/jimd.12218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15863, KAKENHI-PROJECT-19H03624, KAKENHI-PUBLICLY-20H05519
  • [Journal Article] Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis2019

    • Author(s)
      Moutaoufik Mohamed Taha、Malty Ramy、Amin Shahreen、Zhang Qingzhou、Phanse Sadhna、Gagarinova Alla、Zilocchi Mara、Hoell Larissa、Minic Zoran、Gagarinova Maria、Aoki Hiroyuki、、Murayama Kei、Okazaki Yasushi、Foster Leonard J.、Bader Gary D.、Cayabyab Francisco S.、Babu Mohan e
    • Journal Title

      iScience

      Volume: 19 Pages: 1114-1132

    • DOI

      10.1016/j.isci.2019.08.057

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Journal Article] Effects of 5-aminolevulinic acid and sodium ferrous citrate on fibroblasts from individuals with mitochondrial diseases2019

    • Author(s)
      Shimura Masaru、Nozawa Naoko、Ogawa-Tominaga Minako、Fushimi Takuya、Tajika Makiko、Ichimoto Keiko、Matsunaga Ayako、Tsuruoka Tomoko、Kishita Yoshihito、Ishii Takuya、Takahashi Kiwamu、Tanaka Tohru、Nakajima Motowo、Okazaki Yasushi、Ohtake Akira、Murayama Kei
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 10549-10549

    • DOI

      10.1038/s41598-019-46772-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Journal Article] Successful treatment of infantile-onset ACAD9-related cardiomyopathy with a combination of sodium pyruvate, beta-blocker, and coenzyme Q102019

    • Author(s)
      Kadoya T, Sakakibara A, Kitayama K, Yamada Y, Higuchi S, Kawakita R, Kawasaki Y, Fujino M, Murakami Y, Shimura M, Murayama K, Ohtake A, Okazaki Y, Koga Y, Yorifuji T.
    • Journal Title

      J Pediatr Endocrinol Metab

      Volume: 32 Issue: 10 Pages: 1181-1185

    • DOI

      10.1515/jpem-2019-0205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07892, KAKENHI-PROJECT-19H03624
  • [Journal Article] Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome.2019

    • Author(s)
      Borna NN, Kishita Y, Kohda M, Lim SC, Shimura M, Wu Y, Mogushi K, Yatsuka Y, Harashima H, Hisatomi Y, Fushimi T, Ichimoto K, Murayama K, Ohtake A, Okazaki Y.
    • Journal Title

      Neurogenetics

      Volume: 20(1) Issue: 1 Pages: 9-25

    • DOI

      10.1007/s10048-018-0561-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-17F17714, KAKENHI-PROJECT-16K09973
  • [Journal Article] Transition from Leigh syndrome to MELAS syndrome in a patient with heteroplasmic MT-ND3 m.10158T>C2019

    • Author(s)
      Kori Atsuko、Hori Ikumi、Tanaka Tatsushi、Aoyama Kohei、Ito Koichi、Hattori Ayako、Ban Kyoko、Okazaki Yasushi、Murayama Kei、Saitoh Shinji
    • Journal Title

      Brain and Development

      Volume: 41 Issue: 9 Pages: 803-807

    • DOI

      10.1016/j.braindev.2019.05.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-18K19524
  • [Journal Article] A simple method for sequencing the whole human mitochondrial genome directly from samples and its application to genetic testing2019

    • Author(s)
      Yao Yue、Nishimura Motoi、Murayama Kei、Kuranobu Naomi、Tojo Satomi、Beppu Minako、Ishige Takayuki、Itoga Sakae、Tsuchida Sachio、Mori Masato、Takayanagi Masaki、Yokoyama Masataka、Yamagata Kazuyuki、Kishita Yoshihito、Okazaki Yasushi、Nomura Fumio、Matsushita Kazuyuki、Tanaka Tomoaki
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 17411-17421

    • DOI

      10.1038/s41598-019-53449-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KT0019, KAKENHI-PROJECT-17K09004, KAKENHI-PROJECT-18K07408, KAKENHI-PROJECT-18K09593, KAKENHI-PROJECT-19H03624, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-16K19206
  • [Journal Article] Donepezil prevents RANK-induced boneloss via inhibitionofosteoclast differentiation by downregulating acetylcholinesterase.2015

    • Author(s)
      Sato T, Enoki Y, Sakamoto Y, Yokota K, Okubo M, Matsumoto M, Hayashi N, Usui M, Kokabu S, Mimura T, Nakazato T, Araki N, Fukuda T, Okazaki Y, Suda T, Takeda S, Yoda T.
    • Journal Title

      Heliyon

      Volume: 1 Issue: 1 Pages: 1-20

    • DOI

      10.1016/j.heliyon.2015.e00013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462380, KAKENHI-PROJECT-26870543
  • [Journal Article] Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.2014

    • Author(s)
      Matsumoto, Masahiko Okubo, Keisuke Nakashima, Masayuki Yamato, Teruo Okano, Toru Fukuda, Dai Chida, Yuuki Imai, Hisataka Yasuda, Tatsuji Nishihara, Masumi Akita, Hiromi Oda, Yasushi Okazaki, Tatsuo Suda, Tetsuya Yoda
    • Journal Title

      FEBS Lett.

      Volume: 588 Issue: 14 Pages: 2262-2269

    • DOI

      10.1016/j.febslet.2014.05.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25253090, KAKENHI-PROJECT-26293432
  • [Journal Article] Family with sequence familarity 57, member B (Fam57b), a novel peroxisome proliferator-activated receptor g target gene that regulates adipogenesis through ceramide synthesis.2013

    • Author(s)
      Yamashita-Sugahara Y., Tokuzawa, Y., Nakachi, Y., Knesaki-Yatsuka, Y., Matsumoto, M., Mizuno, Y., Okazaki, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Issue: 7 Pages: 4522-4537

    • DOI

      10.1074/jbc.m112.440792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Journal Article] The Paired-box Domain Transcription Factor Pax6 Binds to the Upstream Region of the TRAP Gene Promoter and Suppresses RANKL-induced Osteoclast Differentiation2013

    • Author(s)
      Kogawa M, Hisatake K, Atkins GJ, Findlay DM, Enoki Y, Sato T, Gray PC, Kanesaki-Yatsuka Y, Anerson PH, Wada S, Kato N, Fukuda A, Katayama S, Tsujimoto M, Yoda T, Suda T, Okazaki Y, Matsumoto M
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 43 Pages: 31299-31312

    • DOI

      10.1074/jbc.m113.461848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-25462380
  • [Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012

    • Author(s)
      Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
    • Journal Title

      Diabetologia

      Volume: 55 Suppl 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012

    • Author(s)
      Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
    • Journal Title

      Diabetologia

      Volume: 55 Suppl 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Journal Title

      Diabetologia

      Volume: 55(Suppl1) Issue: S1 Pages: 1-538

    • DOI

      10.1007/s00125-012-2688-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590992, KAKENHI-PROJECT-24659453
  • [Journal Article] IBCAP, Intestine-specific Secretory Protein with Incretin-like Activity2011

    • Author(s)
      Yokoo T, Suzuki H, Shimano H, Watanabe K, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Journal Title

      Diabetes

      Volume: 60 Suppl 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Journal Article] IBCAP, Intestine- specific Secretory Protein with Incretin-like Activity2011

    • Author(s)
      Yokoo T, Suzuki H, Shimano H, Watanabe K, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Journal Title

      Diabetes

      Volume: 60(Suppl1) Issue: Supplement_1 Pages: A521-A548

    • DOI

      10.2337/db11-1929-2041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Journal Article] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Journal Title

      Diabetologia

      Volume: 53(Suppl1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Journal Article] Association of UGT2B7 and ABCB1 genotypes with morphine-induced adverse drug reactions in Japanese patients with cancer2009

    • Author(s)
      FujitaKen-ichi、Ando Yuichi、Yamamoto Wataru、Miya Toshimichi、Endo Hisashi、Sunakawa Yu、Araki Kazuhiro、Kodama Keiji、Nagashima Fumio、Ichikawa Wataru、 Narabayashi Masaru 、Akiyama Yuko 、Kawara Kaori 、Shiomi Mari 、Ogata Hiroyasu 、Iwasa Hiroyasu 、Okazaki Yasushi 、Hirose Takashi 、Sasaki Yasutsuna
    • Journal Title

      Cancer Chemotherapy and Pharmacology in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590542
  • [Patent] 膵内分泌細胞及びその製造方法、並びに分化転換剤2015

    • Inventor(s)
      松本征仁、岡﨑康司、菅原泉
    • Industrial Property Rights Holder
      松本征仁、岡﨑康司、菅原泉
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-07-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Patent] 男性不妊症の予防乃至治療薬、及び食品乃至飼料2014

    • Inventor(s)
      水野由美、岡崎康司
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-162011
    • Filing Date
      2014-08-08
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Patent] 膵臓ホルモン産生細胞の生産方 法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013

    • Inventor(s)
      豊島秀男、岡崎康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-05-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Patent] 新規ペプチド及びその用途2013

    • Inventor(s)
      豊島秀男、岡﨑康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      学校法人 埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-109801
    • Filing Date
      2013
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Patent] 膵臓内分泌細胞の生産方法2013

    • Inventor(s)
      豊島秀男、岡崎康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      埼玉医科大学
    • Filing Date
      2013-05-25
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Patent] 新規ペプチド及びその用途2013

    • Inventor(s)
      豊島秀男、岡崎康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-109801
    • Filing Date
      2013-05-24
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Patent] 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013

    • Inventor(s)
      豊島秀男、岡﨑康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      学校法人 埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Patent] 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013

    • Inventor(s)
      豊島秀男、岡﨑康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      学校法人 埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-05-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Patent] 新規ペプチド及びその用途2013

    • Inventor(s)
      豊島秀男、岡﨑康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      学校法人 埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-109801
    • Filing Date
      2013-05-24
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Patent] ペルオキシソーム生合成および機能に関連する障害を治療および診断するための医薬組成物2012

    • Inventor(s)
      Yasushi Okazaki
    • Industrial Property Rights Holder
      埼玉医科大学
    • Filing Date
      2012-04-06
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Patent] 膵臓内分泌細胞の生産方法2012

    • Inventor(s)
      豊島秀男、岡﨑康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-120281
    • Filing Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Patent] 膵臓内分泌細胞の生産方法2012

    • Inventor(s)
      豊島秀男、岡﨑康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-120281
    • Filing Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Patent] 膵臓内分泌細胞の生産方法2012

    • Inventor(s)
      豊島秀男、岡崎康司、横尾友隆、菅原泉
    • Industrial Property Rights Holder
      埼玉医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-120281
    • Filing Date
      2012-05-25
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Patent] Method of screening for agents that modulate Tysnd1 level or activity in a cell2009

    • Inventor(s)
      Igor Kurochkin, Christian Schoenbsch, Yasushi Okazaki
    • Industrial Property Rights Holder
      埼玉医科大学、理化学研究所
    • Acquisition Date
      2009-10-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Impact of measuring heteroplasmy of a pathogenic mitochondrial DNA variant at the single-cell level in individuals with mitochondrial disease.2023

    • Author(s)
      Yasushi Okazaki
    • Organizer
      Beijing Mitochondrial Workshop
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Presentation] DTC遺伝学的検査とclinical 遺伝学的検査の最新動向2023

    • Author(s)
      岡﨑 康司
    • Organizer
      AGIセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Presentation] ミトコンドリア病遺伝子検査の最新の動向2023

    • Author(s)
      岡﨑 康司
    • Organizer
      第19回日本先天代謝異常学会セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H00424
  • [Presentation] Approaches to Malignant Pleural Mesothelioma by Targeting Epigenetic Modifiers2023

    • Author(s)
      Ken Tajima、Yosuke Miyashita、Aditya Wirawan、Kenta Izumi、Naohisa Matsumoto、Yoichiro Mitsuishi、Yasushi Okazaki、Kazuhisa Takahashi
    • Organizer
      第82回日本癌学会学術総会 Symposia on Specific Tumors/腫瘍別シンポジウム2
    • Data Source
      KAKENHI-PROJECT-23K27465
  • [Presentation] ミトコンドリア病の包括的ゲノム解析からひも解く病態解明2021

    • Author(s)
      岡﨑康司
    • Organizer
      第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会 合同大会
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] 発現解析を基にしたミトコンドリア疾患原因同定2021

    • Author(s)
      長滝谷 芳恵 、新田 和広、大竹 明、村山 圭、岡﨑 康司、木下 善仁
    • Organizer
      第20回日本ミトコンドリア学会年会
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] マルチオミクス解析から明らかにしたミトコンドリア病の原因2021

    • Author(s)
      木下 善仁、新田 和広、大竹 明、村山 圭、岡﨑 康司
    • Organizer
      第20回日本ミトコンドリア学会年会
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア機能関連遺伝子のVUSに対する網羅的な機能的アノテーション2021

    • Author(s)
      杉浦 歩 、木下 善仁、松橋 徹郎、志村 優、小貫 孝則、海老原 知博、新田 和広、岡﨑 敦子 、八塚 由紀子、市野 紀子、伏見 拓矢、 尾崎 心、山田 勇磨、 原島 秀吉、大竹 明 、村山 圭、岡﨑 康司
    • Organizer
      日本ミトコンドリア学会年会第20回
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] Genetic diagnosis of mitocohondrial cardiomyopathy and therapeutic approach to mtiochondrial disease2021

    • Author(s)
      岡﨑康司
    • Organizer
      第86回日本循環器学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア機能関連遺伝子のVUSに対する網羅的な機能的アノテーション2021

    • Author(s)
      杉浦 歩、木下 善仁、松橋 徹郎、志村 優、小貫 孝則、海老原 知博、新田 和広、岡﨑 敦子、八塚 由紀子、市野 紀子、伏見 拓矢、尾崎 心、山田 勇磨、原島 秀吉、大竹 明、村山 圭、岡﨑康司
    • Organizer
      第44回日本分子生物学会年会、パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア病のゲノム解析と治療への展開2021

    • Author(s)
      岡﨑康司
    • Organizer
      ゲノム創薬・創発フォーラム 第9回シンポジウム「ミトコンドリアの機能と疾患から創薬を探る」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] Research and Diagnosis of mitochondrial cardiomyopathy in Japan Mitochondrial Medicine2021

    • Author(s)
      岡﨑康司
    • Organizer
      Workshop Beijing 2021,Web meeting, Beijing Children’s hospital, Capital Medical University
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア呼吸鎖 I欠損患者症のマルチオミクス解析から明らかになったAluを介したNDUFV2遺伝子の欠損2021

    • Author(s)
      木下 善仁、志村 優、神田 将和、伏見 拓矢、新田 和広、八塚 由紀子、大竹 明、村 山 圭、岡崎 康司
    • Organizer
      日本人類遺伝学会第66回大会 第28回日本遺伝子診療学会大会 合同開催
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] 新生児ミトコンドリア心筋症を引き起こすATAD3遺伝子重複の解析2021

    • Author(s)
      木下善仁、岡﨑敦子, 新田和広, 大竹明, 村山圭, 岡﨑康司
    • Organizer
      日本ミトコンドリア学会主催J-mit 特別 オンラインシンポジウム
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] 小児ミトコンドリア病223症例における長期予後および遺伝学的背景に関する検討2021

    • Author(s)
      岡崎 敦子、松永 綾子、八塚 由紀子、 新田 和広、木下 善仁、杉浦 歩、 杉山 洋平、 伏見 拓矢、志村 優、 市本 景子、田鹿 牧子、 海老原 知博、 松橋 徹郎、鶴岡 智子、 原嶋 宏子、 野尻 宗子、中谷 明弘、大竹 明、村山 圭、 岡崎 康司
    • Organizer
      日本人類遺伝学会第66回大会 第28回日本遺伝子診療学会大会 合同開催
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア病の網羅的遺伝子解析2021

    • Author(s)
      岡﨑康司
    • Organizer
      138回特別集談会、北海道大学大学院医学研究院 生殖・発達医学分野 小児科学教室
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] Comprehensive functional annotation of Japanese specific VUS in mitochondrial disease2021

    • Author(s)
      Ayumu Sugiura, Yoshihito Kishita, Tetsuro Matsuhashi, Masaru Shimura, Takanori Onuki, Tomohiro Ebihara, Kazuhiro Nitta, Atsuko Imai-Okazaki, Yukiko Yatsuka, Noriko Ichino, Takuya Fushimi, Kokoro Ozaki, Yuma Yamada, Hideyoshi Harashima, Akira Ohtake, Kei Murayama, Yasushi Okazaki
    • Organizer
      日本人類遺伝学会第66回大会、第28回日本遺伝子診療学会大会 合同開催
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] 新規のATAD3A複合ヘテロ接合性欠損による重度の脊髄低形成症2021

    • Author(s)
      海老原 知博、長友 太郎、鶴岡 智子、 成毛 有紀、 Lim Sze Chern、八塚 由紀子、 木下 善仁、伏見 拓矢、大竹 明、 岡崎 康司、村山 圭
    • Organizer
      日本人類遺伝学会第66回大会 第28回日本遺伝子診療学会大会 合同開催
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア病の遺伝子解析と治療への展開2021

    • Author(s)
      岡﨑康司
    • Organizer
      日本ミトコンドリア学会年会第20回
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] Overcoming The Cheallenges In WGS For Undiagnosed Diseases2020

    • Author(s)
      Okazaki Y
    • Organizer
      12th Annual Next Generation Sequencing & Clinical Diagnostics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] De novo duplications in the ATAD3 locus cause neonatal mitochondrial cardiomyopathy2020

    • Author(s)
      Kishita Y, Imai-Okazaki A, Nitta KR, Ohtake A, Murayama K, Okazaki Y
    • Organizer
      日本人類遺伝学会 第65回大会
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] 次世代シーケンス技術を用いたミトコンドリア呼吸鎖異常症の病態機構の解明2019

    • Author(s)
      岡崎 康司
    • Organizer
      Mitochondria symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] ミトコンドリア関連ゲノム解析と生化学解析から捉える小児代謝性疾患の病態2019

    • Author(s)
      岡崎 康司, 木下 善仁, 村山 圭, 大竹 明
    • Organizer
      第 92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] Delivering Genomic Based Medicine In Japan2019

    • Author(s)
      Yasushi Okazaki
    • Organizer
      11th Annual NGS and Clinical Diagnostics Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03624
  • [Presentation] Providing molecular diagnosis to patients with mitochondrial oxidative phosphorylation disease using functional studies following next generation sequencing.2018

    • Author(s)
      Sze Chern Lim, Yoshihito Kishita, Masakazu Kohda, Tomoko Hirata, Yukiko Yatsuka, Hiroko Harashima, Kei Murayama, Akira Ohtake and Yasushi Okazaki.
    • Organizer
      Variant Effect Prediction Training Course, Johor in Malaysia.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17714
  • [Presentation] Identification of the genetic causes of mitochondrial oxidative phosphorylation (OXPHOS) disease2017

    • Author(s)
      Sze Chern Lim, Yoshihito Kishita, Masakazu Kohda, Yosuke Mizuno, Tomoko Hirata, Yukiko Yatsuka, Nurun Nahar Borna, Hiroko Harashima, Kei Murayama, Akira Ohtake and Yasushi Okazaki.
    • Organizer
      Annual Meeting of the American Society of Human Genetics 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17714
  • [Presentation] ペルオキシソームプロテアーゼTysnd1を欠損したマウスの病態発症機構の解明と改善への試み2017

    • Author(s)
      水野由美, 仲地 豊, 水野洋介, 金田秀貴, 若菜茂晴, 岡崎康司
    • Organizer
      2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会,第90回日本生化学会大会)
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] FGFR1阻害剤は膵内分泌前駆細胞(NGN3+)から内分泌細胞への分化を促進する2017

    • Author(s)
      Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
    • Organizer
      2016日本再生医療学会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-07
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

    • Author(s)
      Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
    • Organizer
      2017 Miami winter Symposium: Diabetes
    • Place of Presentation
      Miami
    • Year and Date
      2017-01-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] Investigation of causative genes for mitochondrial oxidative phosphorylation (OXPHOS) disorders2017

    • Author(s)
      Sze Chern Lim, Yoshihito Kishita, Masakazu Kohda, Tomoko Hirata, Yukiko Yatsuka, Atsuko Imai-Okazaki, Hiroko Harashima, Masaru Shimura, Kei Murayama, Akira Ohtake and Yasushi Okazaki.
    • Organizer
      The 59th Annual Meeting of the Japanese Society for Inherited Metabolic Diseases/The 15th Asian Symposium of Inherited Metabolic Diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17714
  • [Presentation] 性同一性障害当事者DNAをもちいた全エクソーム解析2017

    • Author(s)
      仲地豊, 金沢徹文, 康純, 岡崎康司
    • Organizer
      GID(性同一性障害)学会第19回研究大会
    • Place of Presentation
      札幌医科大学(北海道札幌市)
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-15K15433
  • [Presentation] Tysnd1欠損による造精機能障害はプラスマローゲン前駆体の投与で改善する2017

    • Author(s)
      水野由美, 水野洋介, 梶原 健, 石原 理, 岡崎康司
    • Organizer
      第15回RCGMフロンティアシンポジウム
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] ペルオキシソームで働くプロテアーゼTysnd1を欠損したマウスの脳の形態学的解析2017

    • Author(s)
      水野由美, 穐田真澄, 水野洋介, 仲地 豊, 梶原 健, 岡崎康司
    • Organizer
      第49回 日本臨床分子形態学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] 非コードRNAによるミトコンドリア機能の制御2017

    • Author(s)
      水野 洋介、木下 善仁、神田 将和、岡崎 康司
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16K15531
  • [Presentation] ペルオキシソーム脂質代謝異常マウスの奇形精子に対するバチルアルコール投与の効果2016

    • Author(s)
      水野由美, 金田秀貴, 若菜茂晴, 穐田真澄, 梶原 健, 石原 理, 岡崎康司
    • Organizer
      第57回日本卵子学会
    • Place of Presentation
      新潟県
    • Year and Date
      2016-05-14
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] 性同一性障害当事者DNAをもちいた全エクソーム解析2016

    • Author(s)
      仲地豊, 金沢徹文, 康純, 岡崎康司
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K15433
  • [Presentation] 超並列高速シーケンサーによる性同一性障害当事者ゲノムDNAをもちいた全エクソーム解析2016

    • Author(s)
      仲地豊、金沢徹文、康純、岡崎康司
    • Organizer
      GID(性同一性障害)学会第18回研究大会
    • Place of Presentation
      日本教育会館(東京都千代田区)
    • Year and Date
      2016-03-19
    • Data Source
      KAKENHI-PROJECT-15K15433
  • [Presentation] 新規消化管ホルモン Betagenin は膵β細胞の増殖を刺激し 糖尿病を改善する2015

    • Author(s)
      横尾友隆、渡邉和寿、飯田薫子、鈴木浩明、高島成二、島野仁、山田信博、岡崎康司、豊島秀男
    • Organizer
      第13回 RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学創立30週年記念講堂(埼玉県日高市)
    • Year and Date
      2015-10-31
    • Data Source
      KAKENHI-PROJECT-26670462
  • [Presentation] 新生仔雌マウス脳での遺伝子発現解析による性別違和(性同一性障害)関連遺伝子の探索2015

    • Author(s)
      仲地豊、伊関美緒子、横尾友隆、水野洋介、岡崎康司
    • Organizer
      第35回日本性科学会学術集会
    • Place of Presentation
      埼玉県県民健康センター(埼玉県さいたま市)
    • Year and Date
      2015-10-11
    • Data Source
      KAKENHI-PROJECT-15K15433
  • [Presentation] Tysnd1欠損マウスの脳の表現型解析2015

    • Author(s)
      水野由美, 水野洋介, 昌子浩孝, 仲地 豊, 穐田真澄, 西向めぐみ, 前場良太, 岡崎具樹, 若菜茂晴, Kurochkin Igor V., 宮川 剛, Schönbach Christian, 岡崎康司
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド ( 兵庫県神戸市 )
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] ペルオキシソームの脂質代謝異常によって起こる奇形精子の形態改善への試み2015

    • Author(s)
      水野由美, 穐田真澄, 梶原 健, 石原 理, 岡崎康司
    • Organizer
      第47回 日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      長崎大学 ( 長崎県長崎市 )
    • Year and Date
      2015-09-18
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] 新規消化管ホルモン Betagenin は膵β細胞の増殖を刺激し 糖尿病を改善する2015

    • Author(s)
      横尾友隆、渡邉和寿、飯田薫子、鈴木浩明、高島成二、島野仁、山田信博、岡崎康司、豊島秀男
    • Organizer
      第13回 RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学創立30週年記念講堂(埼玉県日高市)
    • Year and Date
      2015-10-31
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Presentation] DNAのメチル化を介した骨芽細胞分化のエピジェネティクス制御2015

    • Author(s)
      大久保正彦, 松本征仁, 榎木祐一郎, 佐藤毅, 須田立雄, 岡﨑康司, 依田哲也
    • Organizer
      第33回日本骨代謝学会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-22
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] Insulin promoter-Venus/NGN3 promoter-mCherry ダブルノックインhiPS細胞を用いたβ細胞分化誘導の解析2015

    • Author(s)
      菅原 泉, 松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
    • Organizer
      第13回RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学 創立30周年記念講堂 (埼玉県 日高市)
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-25505003
  • [Presentation] ペルオキシソームで働くプロテアーゼTysnd1とプラスマローゲン合成2015

    • Author(s)
      水野由美, 金田秀貴, 若菜茂晴, 西向めぐみ, 前場良太, 梶原 健, 石原 理, 岡崎康司
    • Organizer
      第20回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      ANAクラウンプラザホテルグランコート名古屋 ( 愛知県名古屋市 )
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] ペルオキシソームの脂質代謝機能が低下するTysnd1欠損マウスの網羅的行動解析2015

    • Author(s)
      水野由美, 昌子浩孝, 水野洋介, 仲地 豊, 穐田真澄, 若菜茂晴, 宮川 剛, 岡崎康司
    • Organizer
      第13回RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学創立30周年記念講堂 ( 埼玉県日高市 )
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-26461529
  • [Presentation] Epigenetic control of osteoblast differentiation via DNA methylation2015

    • Author(s)
      Okubo M., Matsumoto M, Mizuno Y, Sato T, Yoda T, Okazaki Y.
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] 新たな破骨細胞分化抑制因子としてのPax6の機能解析2015

    • Author(s)
      大久保正彦, 松本征仁, 甲川昌和, 八塚由紀子, 榎木祐一郎, 佐藤毅, 片山茂裕, 須田立雄, 岡﨑康司, 依田哲也
    • Organizer
      第69回日本口腔科学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2015-05-13
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] 性別違和(性同一性障害)関連遺伝子の探索:マウス発現解析とヒトエクソーム解析によるアプローチ2015

    • Author(s)
      仲地豊、金沢徹文、伊関美緒子、横尾友隆、水野洋介、康純、米田博、岡崎康司
    • Organizer
      BMB2015(第38回日本分子生物学会年会・第88回日本生化学会大会合同大会)
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-15K15433
  • [Presentation] iPS細胞を用いた、新規消化管ホルモンIBCAPが膵β細胞分化に与える影響の検討2014

    • Author(s)
      菅原 泉、横尾 友隆、渡邊 和寿、飯田 薫子、鈴木 浩明、島野 仁、山田 信博、岡﨑 康司、豊島 秀男
    • Organizer
      第57回 日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Presentation] iPS細胞を用いた、新規消化管ホルモンIBCAPが膵β細胞分化に与える影響の検討2014

    • Author(s)
      菅原 泉、横尾 友隆、渡邊 和寿、飯田 薫子、鈴木 浩明、島野 仁、山田 信博、岡﨑 康司、豊島 秀男
    • Organizer
      第57回 日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PROJECT-26670462
  • [Presentation] 消化管ホルモンIBCAPによる膵β細胞分化増殖に与える影響2013

    • Author(s)
      豊島秀男、横尾友隆、鈴木浩明、石川三衛、川上正舒、島野仁、山田信博、岡崎康司
    • Organizer
      第86回日本内分泌学会学術集会
    • Place of Presentation
      宮城県仙台市
    • Year and Date
      2013-04-25
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] ヒトiPS細胞におけるヘルパー依存型アデノウィルスを用いたInsulin promoter-Venusレポーター細胞の作製とその解析2013

    • Author(s)
      菅原泉 松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
    • Organizer
      第11回 RCGMシンポジウム
    • Place of Presentation
      埼玉日高市
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] Self-limiting system of osteoclast differentiation by the Paired-box Domain Transcription factor Pax62013

    • Author(s)
      Masahito Matsumoto, Masakazu Kogawa, Koji Hisatake, Gerald J. Atkins, David M. Findlay, Yuichiro Enoki, Tsuyoshi Sato, Peter C. Gray8, Yukiko Kanesaki-Yatsuka5, Paul H. Anderson9, Seiki Wada2, Naoki Kato4, Aya Fukuda1,7, Shigehiro Katayama, Masafumi Tsujimoto, Tetsuya Yoda, Tatsuo Suda, Yasushi Okazaki
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] 膵β細胞分化における消化管ホルモンIBCAPの役割2013

    • Author(s)
      横尾友隆、菅原泉、渡邊和寿、鈴木浩明、島野仁、山田信博、岡崎康司、豊島秀男
    • Organizer
      第11回RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉県日高市
    • Year and Date
      2013-11-23
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] Dual functional roles of Pax6 in the regulation of bone and glucose metabolism Osteoclast Differentiation.2013

    • Author(s)
      Kogawa, M., Hisatake, K., Atkins, G.J., Findlay, D.M., Enoki, Y., Sato, Tsuyoshi, Gray, P, Wada, S., Kato, N., Fukuda, A., Katayama, S., Tsujimoto, M., Yoda, T., Suda, T., Okazaki, Y., and Matsumoto, M.
    • Organizer
      ASBMR
    • Place of Presentation
      Maryland USA
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] 新規消化管ホルモンIBCAPによる膵β細胞分化・増殖作用の解析2013

    • Author(s)
      横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、岡崎康司、豊島秀男
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本県熊本市
    • Year and Date
      2013-05-16
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H.
    • Organizer
      48th EASD Annual Meeting
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2012-10-02
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012

    • Author(s)
      Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
    • Organizer
      第48回 欧州糖尿病学会議 (EASD)
    • Place of Presentation
      Messe Berlin(ドイツ、ベルリン)
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] Effect of IBCAP, a Novel Intestine-specific Secretory Protein, on Pancreatic β-cell Differentiation.2012

    • Author(s)
      Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
    • Organizer
      第10回 RCGMフロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] Effect of IBCAP, a Novel Intestine-specific Secretory Protein, on Pancreaticβ-cell Differentiation2012

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Yamada N, Okazaki Y, Toyoshima H.
    • Organizer
      第10回RCGMフロンティア国際シンポジウム
    • Place of Presentation
      埼玉県日高市
    • Year and Date
      2012-11-03
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Organizer
      48th EASD Annual Meeting
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2012-10-02
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] Effect of IBCAP, a Novel Intestine-specific Secretory Protein, on Pancreatic β-cell Differentiation.2012

    • Author(s)
      Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
    • Organizer
      第10回 RCGMフロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] エキソーム配列解析を用いたミトコンドリア呼吸鎖複合体異常症(MRCD)の原因遺伝子の系統的探索2012

    • Author(s)
      岡崎康司
    • Organizer
      東京工業大学・東京工業大学大学院GP「情報学と生命医学の発展的融合教育の新展開」シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012

    • Author(s)
      Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
    • Organizer
      第48回 欧州糖尿病学会議 (EASD)
    • Place of Presentation
      Messe Berlin(ドイツ、ベルリン)
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] ゲノム医学教育センターから発信するトランスレーショナルリサーチへの展開2012

    • Author(s)
      岡崎康司
    • Organizer
      GDNSS「専門医育成と医師不足解消を目指して」公開フォーラム
    • Place of Presentation
      群馬県前橋市(招待講演)
    • Year and Date
      2012-02-10
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] エキソーム配列解析を用いたミトコンドリア呼吸鎖複合体異常症(MRCD)の原因遺伝子の系統的探索2012

    • Author(s)
      岡崎康司
    • Organizer
      東京工業大学・東京工業大学大学院GP「情報学と生命医学の発展的融合教育の新展開」シンポジウム
    • Place of Presentation
      東京都目黒区(招待講演)
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] 大学病院における人材育成の未来像~「臨床研究・リサーチマインド・地域医療への貢献」の視点から~2012

    • Author(s)
      岡崎康司
    • Organizer
      GDNSS「専門医育成と医師不足解消を目指して」公開フォーラム
    • Place of Presentation
      群馬
    • Year and Date
      2012-02-10
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Tysnd1 deficiency interferes with mouse peroxisomal functions2011

    • Author(s)
      Yumi Mizuno, Yuichi Ninomiya, Mioko Iseki, Hiroyasu Iwasa, Yutaka Nakachi, Masumi Akita, Toru Tsukui, Chizuru Ito, Kiyotaka Toshimori, Nobuyuki Shimozawa, Megumi Nishimukai, Hiroshi Hara, Ryota Maeba, Tomoki Okazaki, Yasushi Horai, Mitsuhiro Watanabe, Hir
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] 新規消化管ホルモン因子IBCAPによる膵β細胞増加作用の解析2011

    • Author(s)
      横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、岡崎康司、豊島秀男
    • Organizer
      第26回 日本糖尿病合併症学会
    • Place of Presentation
      さいたま市
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] 膵 β 細胞増加作用を持つ新規消化管特異的分泌タンパクIBCAPの機能解析2011

    • Author(s)
      横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、岡崎康司、豊島秀男
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌市
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] 核にコードされた遺伝子異常によるミトコンドリア呼吸鎖複合体異常症(MRCD)の系統的探索2011

    • Author(s)
      岡崎康司
    • Organizer
      第53回日本先天代謝異常学会総会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] 新規消化管特異的分泌因子IBCAPの機能解析および糖尿病治療への可能性2011

    • Author(s)
      豊島秀男 [招待演者]、横尾友隆、鈴木浩明、石川三衛、川上正舒、島野仁、山田信博、岡崎康司
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      神戸市
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] Tysnd1欠損細胞を用いたペルオキシソームタンパク質の細胞内局在解析2011

    • Author(s)
      水野由美, 伊関美緒子, 穐田真澄, 水野洋介, 岡崎康司
    • Organizer
      第9回RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉県
    • Year and Date
      2011-11-03
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Demonstration of IBCAP as a Novel Intestine- specific Secretory Protein with Incretin-like Activity2011

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Organizer
      第34回 日本分子生物学学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] IBCAP, Intestine-specific Secretory Protein with Incretin-like Activity2011

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Organizer
      The 71st Scientific Sessions of America Diabetes Association
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] 核にコードされた遺伝子異常によるミトコンドリア呼吸鎖複合体異常症(MRCD)の系統的探索2011

    • Author(s)
      岡崎康司
    • Organizer
      第53回日本先天代謝異常学会総会
    • Place of Presentation
      千葉県千葉市(招待講演)
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Tysnd1欠損マウスの機能解析2010

    • Author(s)
      水野由美, 二宮裕一, 伊関美緒子, 穐田真澄, 津久井通, 伊藤千鶴, 年森清隆, 下澤伸行, 茂木浩未, 若菜茂晴, 野田哲生, 西向めぐみ, 原博, 前場良太, 岡崎具樹, Kurochkin Igor V., 岩佐泰靖, 水野洋介, Schoenbach Christian, 岡崎康司
    • Organizer
      BMB2010第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Functional analysis of Peroxisomal Processing Protease using Tysnd1 deficient Mice2010

    • Author(s)
      Yumi Mizuno, Yuichi Ninomiya, Mioko Iseki, Masumi Akita, Toru Tsukui, Yosuke Mizuno, Yasushi Okazaki
    • Organizer
      8th RCGM International Symposium of Academic Frontier
    • Place of Presentation
      埼玉県
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-21590344
  • [Presentation] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010

    • Author(s)
      Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
    • Organizer
      46th EASD Annual Meeting
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22590992
  • [Presentation] 消化管ホルモンIBCAPによる膵β細胞分化増殖に与える影響

    • Author(s)
      豊島 秀男、横尾 友隆、鈴木 浩明、石川 三衛、川上 正舒、島野 仁、山田 信博、岡崎 康司
    • Organizer
      第86回 日本内分泌学会学術総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Presentation] Effect of Betagenin on Pancreatic beta-cell Proliferation and Differentiation

    • Author(s)
      Tomotaka Yokoo, Yizumi Yamashita Sugawara, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, Nobuhiro Yamada, Yasushi Okazaki, Hideo Toyoshima
    • Organizer
      第12回 RCGMフロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学30周年記念講堂(埼玉県日高市)
    • Year and Date
      2014-10-31 – 2014-11-01
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Presentation] Effect of Betagenin on Pancreatic beta-cell Proliferation and Differentiation

    • Author(s)
      Tomotaka Yokoo, Yizumi Yamashita Sugawara, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, Nobuhiro Yamada, Yasushi Okazaki, Hideo Toyoshima
    • Organizer
      第12回 RCGMフロンティア国際シンポジウム
    • Place of Presentation
      埼玉医科大学30周年記念講堂(埼玉県日高市)
    • Year and Date
      2014-10-31 – 2014-11-01
    • Data Source
      KAKENHI-PROJECT-26670462
  • [Presentation] 消化管ホルモンIBCAPによる膵β細胞分化増殖に与える影響

    • Author(s)
      豊島 秀男、横尾 友隆、鈴木 浩明、石川 三衛、川上 正舒、島野 仁、山田 信博、岡崎 康司
    • Organizer
      第86回 日本内分泌学会学術総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] 膵β細胞分化における消化管ホルモンIBCAPの役割

    • Author(s)
      横尾 友隆、菅原 泉、渡邉 和寿、鈴木 浩明、島野 仁、山田 信博、岡崎 康司、豊島 秀男
    • Organizer
      第11回 RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学30周年記念講堂(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-24659453
  • [Presentation] 新規消化管ホルモンIBCAPによる膵β細胞分化・増殖作用の解析

    • Author(s)
      横尾 友隆、渡邊 和寿、飯田 薫子、鈴木 浩明、島野 仁、石川 三衛、川上 正舒、山田 信博、岡崎 康司、豊島 秀男
    • Organizer
      第56回 日本糖尿病学会年次学術集会
    • Place of Presentation
      テトリア熊本ビル(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Presentation] 膵β細胞分化における消化管ホルモンIBCAPの役割

    • Author(s)
      横尾 友隆、菅原 泉、渡邉 和寿、鈴木 浩明、島野 仁、山田 信博、岡崎 康司、豊島 秀男
    • Organizer
      第11回 RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学30周年記念講堂(埼玉県日高市)
    • Data Source
      KAKENHI-PROJECT-25461395
  • [Presentation] 新規消化管ホルモンIBCAPによる膵β細胞分化・増殖作用の解析

    • Author(s)
      横尾 友隆、渡邊 和寿、飯田 薫子、鈴木 浩明、島野 仁、石川 三衛、川上 正舒、山田 信博、岡崎 康司、豊島 秀男
    • Organizer
      第56回 日本糖尿病学会年次学術集会
    • Place of Presentation
      テトリア熊本ビル(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24659453
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