NISHIDA Keiichiro 西田圭一郎

Researcher Number	80284058
Other IDs
External Links
Affiliation (Current)	2025: 岡山大学, 医療開発領域, 教授
Affiliation (based on the past Project Information) *help	2025: 岡山大学, 医療開発領域, 教授 2023 – 2024: 岡山大学, 大学病院, 教授 2020 – 2023: 岡山大学, 医歯薬学域, 准教授 2016 – 2020: 岡山大学, 医歯薬学総合研究科, 准教授 2011 – 2016: 岡山大学, 医歯(薬)学総合研究科, 准教授 … More 2015: 岡山大学, 大学院医歯薬学研究科, 準教授 2014: 岡山大学, 大学院医歯薬学総合研究科, 准教授 2007 – 2013: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Human morphology, Associate Professor 2006: 岡山大学, 大学院・医歯薬学総合研究科, 助教授 2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 助教授 2004: Okayama University, Graduate School of Medicine and Dentistry, Associate Professor, 大学院・医歯学総合研究科, 助教授 2002 – 2003: 岡山大学, 大学院・医歯学総合研究科, 助手 1999 – 2001: 岡山大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Basic Section 59010:Rehabilitation science-related / Basic Section 47040:Pharmacology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator メカニカルストレス / 軟骨細胞 / 変形性関節症 / microRNA / エピジェネティクス / ヒストン脱アセチル化酵素阻害剤 / 関節リウマチ / アポトーシス / ADAM12 / 新規疾患修飾性OA治療薬 … More / 疾患修飾性OA治療薬 / 軟骨代謝 / miRNA / HYBID / ヒアルロン酸分解酵素 / リンパ腫 / 抗体療法 / ブレンツキシマブ・ベトチン / ブレンツキシマブベトチン / 滑膜線維芽細胞 / コラーゲン抗体誘導関節炎モデル / ブレンツキシマブ・ベドチン / CD30 / 関節リモデリング / miR-29b / HDAC / マイクロアレイ解析 / electroporation / siRNA / コラーゲン抗体誘導関節炎 / HDAC1 / lipofecton法 / 関節炎 / Lipofection法 / 抗コラーゲン抗体誘導関節炎 / エレクトロポレーション / 遺伝子導入 / ヒストン脱アセチル化酵素 / ピストン脱アセチル化酵素阻害剤 / interleukin-4 / ADAMTS-5 / MMP-13 / RUNX2 / chondrocyte / mechanical stress / アグリカナーゼ / 軟骨破壊 / HIF-1 / 破骨細胞 / トリコスタチンA / 滑膜炎 / ヒストン脱アセチル化 / MMP / コラーゲン関節炎 / FK228 / Trichostatin A / VEGF / HIF-1α / 酸化ストレス / 低酸素 / インターロイキン4 / 一酸化窒素 / 力学的負荷 / カスパーゼ / 一酸化窒素(NO) … More Except Principal Investigator 軟骨 / アグリカナーゼ / 細胞外マトリックス / 変形性関節症 / 遺伝子 / ADAMTS / メカニカルストレス / 関節炎 / メタロプロテアーゼ / マトリックス / アグリカン / ヒアルロン酸 / X線 / プロテオグリカン / 関節軟骨 / 医療・福祉 / 血管新生 / 疼痛 / HRG / 軟骨細胞 / miRNA / エクソソーム / aggrecanase / 関節病学 / メカノセンサー / マトリックスメタロプロテアーゼ / MRI / 生体イメージング / 細胞外分泌小胞 / TNF / 変形性膝関節症 / HMGB1 / 慢性痛 / 神経障害性疼痛 / 炎症性メディエーター / 血管内皮細胞 / IL-33 / IL33 / DAMP / ヒスタミン / 血漿糖タンパク質 / 炎症生サイトカイン / 慢性炎症性疾患 / microRNA / 遺伝子改変マウス / 生後発達 / 骨成長板 / 炎症性サイトカイン / 細胞外小胞 / CAF / EMT / がん / micro RNA / コラーゲン / プローブ / 組織再生 / Ｘ線 / nano CT / 軟骨変性 / extracellular matrix / arthritis / matrix metalloprotease / rheumatoid arthritis / リウマチ性関節炎 / X線造影剤 / 蛍光 / 創薬 / 動物モデル / 診断 / 造影剤 / 画像解析 / 関節 / 分子標的化 / デュアルモードプローブ / バイオフィルム / 感染症 / 骨髄間質細胞 / 血管内皮細胞増殖因子(VEGF) / 骨再生 / 骨芽細胞 / 間葉系幹細胞 / 骨芽細胞分化 / コラーゲン誘導関節炎 / p53 / アポトーシス / 滑膜線維芽細胞 / 慢性関節リウマチ / メソトレキセート Less

変形性関節症への細胞外分泌小胞最適化：細胞間クロストークとマルチオミクス解析応用
- Principal Investigator
  
  廣畑聡
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Okayama University
Role of TNF-alpha in knee osteoarthritis pain and analgesic effect of plasma protein HRG
- Principal Investigator
  
  ハティポールオメル・ファルク
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Mechanism of hyaluronan-degrading enzyme HYBID expression by chondrocytes and its regulation by microRNAsPrincipal Investigator
- Principal Investigator
  
  西田圭一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Okayama University
Cartilage protection by mechanical stress - changes of Exosome contents-
- Principal Investigator
  
  大月孝志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Okayama University
Homeostatic effect of improvement candidate drug targeting IL-33
- Principal Investigator
  
  Hatipoglu Omer Faruk
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kindai University
神経障害性疼痛患者におけるHMGB1を用いた新規診断体系の確立
- Principal Investigator
  
  鉄永倫子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Okayama University
CD30 targeted therapy induces apoptosis of inflammatory cytokine-stimulated synovial fibroblasts and ameliorates collagen antibody-induced arthritis in micePrincipal Investigator
- Principal Investigator
  
  Nishida Keiichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Okayama University
Decipher cell-cell interactions
- Principal Investigator
  
  廣畑聡
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Okayama University
Role of Aggrecan in the postnatal development of bone and cartilage.
- Principal Investigator
  
  大橋俊孝
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Okayama University
Regulatory system of microRNA and ADAM12 expression in the process of joint remodelingPrincipal Investigator
- Principal Investigator
  
  Nishida Keiichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Comprehensive analysis of exosomes in cartilage and approach to the new strategy for osteoarthritis therapy
- Principal Investigator
  
  HIROHATA SATOSHI
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Analysis of cartilage protection by mechanical stress -miRNA and extracellular vesicles functions in osteoarthritis-
- Principal Investigator
  
  Ohtsuki Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Establishment of in vivo imaging and quantification of articular cartilage by using a cartilage-specific probe.
- Principal Investigator
  
  Oohashi Toshitaka
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Integrated analysis of microRNAs that regulate cartilage damage and its functional analysis in chondrocytes
- Principal Investigator
  
  HIROHATA SATOSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Epigenetic regulation of miRNA induced by mechanical stress in human chondrocytesPrincipal Investigator
- Principal Investigator
  
  Nishida Keiichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
New approach of hyaluronan as osteoarthritis drug and analysis of articular cartilage protection mechanism
- Principal Investigator
  
  Ohtsuki Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Creation of articular cartilage-specific bio-molecular imaging probe with potentials of dual modalities.
- Principal Investigator
  
  OOHASHI Toshitaka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Regulatory mechanism of transcriptional factors and microRNA in arthritis
- Principal Investigator
  
  HIROHATA Satoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Inhibition of experimental arthritis in mice by small interfering RNA targeting histone deacetylase 1 (siHDAC1) using in vivo electroporation methodPrincipal Investigator
- Principal Investigator
  
  NISHIDA Keiichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Development of cartilage directed multifunctional nano-probes for diagnosis and treatment of osteoarthritis.
- Principal Investigator
  
  OOHASHI Toshitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
echanism of cartilage protection by hyaluronan
- Principal Investigator
  
  OHTSUKI Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Aggrecanase regulation system in osteoarthritis and strategy for early diagnosis and therapy for osteoarthritis
- Principal Investigator
  
  HIROHATA Satoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Elucidation of the mechanism of aggrecan degradation and epigenetic regulation of aggrecanase expression in osteoarthritic cartilagePrincipal Investigator
- Principal Investigator
  
  NISHIDA Keiichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
軟骨基質イメージング用マルチモードプローブ開発による変形性関節症治療の新戦略
- Principal Investigator
  
  大橋俊孝
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
マイクロバブルを用いた骨・関節感染症の治療
- Principal Investigator
  
  阿部信寛
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Inducible mechanism and role of novel aggrecanase in early stage of arthritis and its therapeutic application
- Principal Investigator
  
  HIROHATA Satoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
ヒストン脱アセチル化阻害による関節リウマチの炎症および骨・軟骨破壊の抑制法の開発Principal Investigator
- Principal Investigator
  
  西田圭一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
力学的負荷による軟骨細胞の遺伝子発現変化に基づく変形性関節症の新規治療薬開発Principal Investigator
- Principal Investigator
  
  西田圭一郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
Toe role of novel aggrecanase in rheumatoid arthritis and its diagnostic potential
- Principal Investigator
  
  HIROHATA Satoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
骨細胞系譜への分化に寄与する因子の同定と骨再生への応用
- Principal Investigator
  
  井上一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
メソトレキセートによる慢性関節リウマチ滑膜細胞のアポトーシス誘導作用の解析
- Principal Investigator
  
  井上一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University
変形性関節症軟骨細胞の細胞周期制御とアポトーシスに関する研究Principal Investigator
- Principal Investigator
  
  西田圭一郎
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Okayama University

[Book] 関節軟骨のイメージング. 第2章基礎. 最新醫學別冊診断と治療のABC. 変形性関節症.2017
- Author(s)
  西田圭一郎、大橋俊孝
- Total Pages
  206
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-15K15551
[Book] 知っておくべき　整形外科医の関節リウマチ診療ABC2016
- Author(s)
  西田圭一郎
- Total Pages
  226
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-26462299
[Book] NEW MOOK整形外科リウマチ類縁疾患(変形性関節症軟骨にみられる軟骨破壊機序)2004
- Author(s)
  西田圭一郎, 松尾真嗣, 井上一
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-15790791
[Book] 先端医療シリーズ22:「整形外科の最新医療」(変形性関節症における軟骨破壊とNO)(平澤泰介, 井上一, 高岡邦夫ほか・編)2003
- Author(s)
  西田圭一郎, 土井英之, 藤原一夫, 井上一
- Publisher
  先端医療技術研究所
- Data Source
  KAKENHI-PROJECT-15790791
[Journal Article] Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial Hypertension2023
- Author(s)
  Akagi Satoshi、Nakamura Kazufumi、Kondo Megumi、Hirohata Satoshi、Udono Heiichiro、Nishida Mikako、Saito Yukihiro、Yoshida Masashi、Miyoshi Toru、Ito Hiroshi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 15 Pages: 5028-5028
- DOI
  10.3390/jcm12155028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08108, KAKENHI-PROJECT-20H00548
[Journal Article] CD30-targeted therapy induces apoptosis of inflammatory cytokine-stimulated synovial fibroblasts and ameliorates collagen antibody-induced arthritis in mice2022
- Author(s)
  Matsuhashi M, Nishida K, Sakamoto M, Gion Y, Yoshida A, Katsuyama T, Nakahara R, Nasu Y, Matsumoto Y, Sato Y, Ozaki T.
- Journal Title
  
  Inflammation Research
  
  Volume: 71 Issue: 2 Pages: 215-226
- DOI
  10.1007/s00011-021-01537-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09433
[Journal Article] Induction of CEMIP in chondrocytes by inflammatory cytokines: underlying mechanisms and potential involvement in osteoarthritis.2020
- Author(s)
  Ohtsuki T, Hatipoglu OF, Asano K, Inagaki J, Nishida K, Hirohata S.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 9 Pages: 3140-3140
- DOI
  10.3390/ijms21093140
- NAID
  120006860099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04313, KAKENHI-PROJECT-17K11009, KAKENHI-PROJECT-19K11791, KAKENHI-PROJECT-19K09627, KAKENHI-PROJECT-20H00548
[Journal Article] Involvement of ADAM12 in Chondrocyte Differentiation by Regulation of TGF-β1-Induced IGF-1 and RUNX-2 Expressions2019
- Author(s)
  Horita M, Nishida K, Hasei J, Furumatsu T, Sakurai M, Onodera Y, Fukuda K, Salter DM, Ozaki T.
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 印刷中 Issue: 1 Pages: 97-106
- DOI
  10.1007/s00223-019-00549-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11010, KAKENHI-PROJECT-16K20055
[Journal Article] Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 12019
- Author(s)
  Ohtsuki T, Shinaoka A, Kumagishi-Shinaoka K, Asano K, Hatipoglu OF, Inagaki J, Takahashi K, Oohashi T, Nishida K, Naruse K, Hirohata S
- Journal Title
  
  Experimental Cell Research.
  
  Volume: 383 Issue: 2 Pages: 111556-111556
- DOI
  10.1016/j.yexcr.2019.111556
- NAID
  120006842048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09627, KAKENHI-PROJECT-19K11791, KAKENHI-PROJECT-17H04313, KAKENHI-PROJECT-17K11009, KAKENHI-PROJECT-17K11010
[Journal Article] High molecular weight hyaluronan protects cartilage from degradation by inhibiting aggrecanase expression.2018
- Author(s)
  Ohtsuki T, Asano K, Inagaki J, Shinaoka A, Kumagishi-Shinaoka K, Cilek MZ, Hatipoglu OF, Oohashi T, Nishida K, Komatsubara I, Hirohata S.
- Journal Title
  
  J Orthop Res
  
  Volume: 36 Issue: 12 Pages: 3247-3255
- DOI
  10.1002/jor.24126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11009, KAKENHI-PROJECT-17H04313, KAKENHI-PROJECT-17K19727, KAKENHI-PROJECT-16K20358
[Journal Article] ADAM122018
- Author(s)
  堀田昌宏、西田圭一郎
- Journal Title
  
  整形外科
  
  Volume: 69 Pages: 848-848
- Data Source
  KAKENHI-PROJECT-17K11010
[Journal Article] High molecular weight hyaluronan protects cartilage from degradation by inhibiting aggrecanase expression.2018
- Author(s)
  Ohtsuki T, Asano K, Inagaki J, Shinaoka A, Kumagishi-Shinaoka K, Cilek MZ, Hatipoglu OF, Oohashi T, Nishida K, Komatsubara I, Hirohata S.
- Journal Title
  
  J Orthop Res.
  
  Volume: 36 Pages: 3247-3255
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10905
[Journal Article] Dramatic Effect of Tofacitinib on TNFInhibitor Resistant Synovitis: A Case Report.2016
- Author(s)
  Nishida K, Natsumeda M, Nasu Y, Ezawa K.
- Journal Title
  
  Rheumatology (Sunnyvale)
  
  Volume: 6 Issue: 01 Pages: 185-185
- DOI
  10.4172/2161-1149.1000185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462299
[Journal Article] Hyaluronan suppresses mechanical stress-induced expression of catabolic enzymes by human chondrocytes via inhibition of IL-1β production and subsequent NF-κB activation2015
- Author(s)
  Ozawa M, Nishida K, Yoshida A, Saito T, Harada R, Machida T, Ozaki T
- Journal Title
  
  Inflammation Res
  
  Volume: 64 Issue: 3-4 Pages: 243-252
- DOI
  10.1007/s00011-015-0804-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462299
[Journal Article] 関節リウマチ－関節破壊の機序を中心に－2015
- Author(s)
  原田遼三, 西田圭一郎
- Journal Title
  
  リウマチ科
  
  Volume: 53 Pages: 227-232
- Data Source
  KAKENHI-PROJECT-26462299
[Journal Article] 軟骨細胞. リウマチ性疾患における骨軟骨破壊に関わる細胞たち.2015
- Author(s)
  西田圭一郎
- Journal Title
  
  Keynote R.A
  
  Volume: 3 Pages: 113-116
- Data Source
  KAKENHI-PROJECT-26462299
[Journal Article] Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells2011
- Author(s)
  Tetsunaga T, et al.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 19(2) Issue: 2 Pages: 222-232
- DOI
  10.1016/j.joca.2010.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112511, KAKENHI-PROJECT-23390366
[Journal Article] 関節軟骨のバイオイメーブング2011
- Author(s)
  大橋俊孝、西田圭一郎
- Journal Title
  
  clinical Calcium
  
  Volume: 21(6) Pages: 100-106
- Data Source
  KAKENHI-PROJECT-22591686
[Journal Article] Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells.2011
- Author(s)
  Tetsunaga T, Nishida K, Furumatsu T, Naruse K, Hirohata S, Yoshida A, Saito T, Ozaki T.
- Journal Title
  
  Osteoarthritis Cartilage. 19(2)
  
  Pages: 222-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390399
[Journal Article] 関節軟骨のバイオイメージング2011
- Author(s)
  大橋俊孝、西田圭一郎
- Journal Title
  
  Clinical Calcium
  
  Volume: 21(6) Pages: 100-106
- Data Source
  KAKENHI-PROJECT-22591686
[Journal Article] Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells.2010
- Author(s)
  Tetsunaga T, Nishida K, Furumatsu T, Naruse K, Hirohata S, Yoshida A, Saito T, Ozaki T.
- Journal Title
  
  Osteoarthritis and Cartilage 19
  
  Pages: 222-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SWI353 chondrocyte-like cells.2010
- Author(s)
  Tetsunaga T, Nishida K, Furumatsu T, Naruse K, Hirohata S, Yoshida A, Saito T, Ozaki T.
- Journal Title
  
  Osteoarthritis and Cartilage
  
  Volume: 19 Pages: 222-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis.2010
- Author(s)
  Kawabata T, Nishida K, Takasugi K, Ogawa H, Sada K, Kadota Y, Inagaki J, Hirohata S, Ninomiya Y, Makino H.
- Journal Title
  
  Arthritis Res Ther. 12(4):
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390399
[Journal Article] メカニカルストレスと軟骨破壊2009
- Author(s)
  西田圭一郎
- Journal Title
  
  臨床リウマチ 21
  
  Pages: 92-94
- NAID
  130005141214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification.2009
- Author(s)
  Kumagishi K, Nishida K, Yamaai T, Momota R, Miyaki S, Hirohata S, Naito I, Asahara H, Ninomiya Y, Ohtsuka A.
- Journal Title
  
  Arch Histol Cytol. 72(3)
  
  Pages: 175-185
- NAID
  10027156928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390399
[Journal Article] Up-regulation of Runx2 and proteolytic enzymes by cyclic tensile stress in chondrocyte-like cells2008
- Author(s)
  T. Tetsunaga, K. Nishida, S. Hirohata, K. Naruse, T. Ozaki
- Journal Title
  
  Modern Rheumatology 18
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Intra-articular injection of interleukin-4 decreases nitric oxide production by ehondrocytes and ameliorates subsequent destruction of cartilage in instability-induced osteoarthritis in rat knee joints2008
- Author(s)
  Yorimitsu M, Nishida K, Shimizu A, Doi H, Miyazawa s, Komiyama T, Nasu Y. Yoshida A, Watanabe S Ozaki T
- Journal Title
  
  Osteoarthritis and Cartilage 16
  
  Pages: 764-771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model2008
- Author(s)
  Nasu Y, Nishida K, Miyazawa s, Komiyama T, Kadota Y, Abe N. Yoshida A, Hirohata s, Ohtsuka A Ozaki T
- Journal Title
  
  Osteoarthritis and Cartilage ]6
  
  Pages: 723-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] 軟骨細胞様細胞においてIL-4は力学的負荷誘導性のCbfal/Runx2およびMMP-13、ADAMTS-5の発現を抑制する2008
- Author(s)
  鉄永智紀, 西田圭一郎, 古松毅之, 吉田晶, 国定俊之, 成瀬恵治, 尾崎敏文
- Journal Title
  
  日本整形外科学会雑誌 82
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Interleukin-4 downregulates the cyclic tensile stress-induced matrix metalloproteinases-13 and cathepsin Bexpression by rat normal chondrocytes2008
- Author(s)
  Doi H, Nishida K. Yorimitsu M, Komiyama T, Kadota Y, Tetsunaga T, Yoshida A. Kubota S, Taki gawa M Ozaki T
- Journal Title
  
  Acta Medica Okayama 62
  
  Pages: 119-126
- NAID
  120002305656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model.2008
- Author(s)
  Nasu Y, Nishida K, Miyazawa S, Manabe H, Komiyama T, Kadota Y, Yoshida A, Abe N, Hirohata S, Ohtsuka A, Ozaki T.
- Journal Title
  
  Osteoarthritis and Cartilage 16(6):
  
  Pages: 723-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390399
[Journal Article] Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts2008
- Author(s)
  Manabe H, Nasu Y, Komiyama T, Furumatsu T. Kitamura A, Miyazawa S. Ninomiya, Y, Ozaki T. Asahara H, Nishida K.
- Journal Title
  
  Inflammation Research 57
  
  Pages: 4-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591780
[Journal Article] Trichostatin Aによるマウス抗コラーゲン抗体誘導関節炎の軟骨破壊抑制効果2006
- Author(s)
  那須義久, 西田圭一郎, 他
- Journal Title
  
  日本整形外科学会雑誌 80(8)
- Data Source
  KAKENHI-PROJECT-17659470
[Journal Article] Suppression of the joint inflammation and cartilage destruction of collagen antibody-induced arthritis in mice by histone deacechylase inhibitor.2006
- Author(s)
  Nasu Y, Nishida K, et al.
- Journal Title
  
  APLAR Journal of Rheumatology 9(Suppl1)
- Data Source
  KAKENHI-PROJECT-17659470
[Journal Article] ヒストン脱アセチル化酵素阻害剤によるRAの血管新生阻害機序2006
- Author(s)
  真鍋博規, 西田圭一郎, 他
- Journal Title
  
  岡山医学会雑誌 118(2)
  
  Pages: 172-172
- Data Source
  KAKENHI-PROJECT-17659470
[Journal Article] ヒストンデアセチラーゼ阻害剤によるリウマチ炎症の抑制.2005
- Author(s)
  西田圭一郎, 真鍋博規
- Journal Title
  
  医学のあゆみ Vol.213, No.12
  
  Pages: 1027-1031
- Data Source
  KAKENHI-PROJECT-17659470
[Journal Article] ヒストン脱アセチル化酵素阻害剤による関節炎の制御と関節破壊抑制2005
- Author(s)
  西田圭一郎
- Journal Title
  
  分子リウマチ Vol.2, No.2
  
  Pages: 3-10
- Data Source
  KAKENHI-PROJECT-17659470
[Journal Article] 整形外科領域におけるHDAC阻害剤の可能性2005
- Author(s)
  那須義久, 西田圭一郎
- Journal Title
  
  関節外科 Vol.25, No.2
  
  Pages: 98-99
- Data Source
  KAKENHI-PROJECT-17659470
[Journal Article] 変形性関節症の発症機序-NOからみたOA治療へのアプローチ2004
- Author(s)
  西田圭一郎, 清水晃, 依光正則, 土井英之, 相賀礼子, 井上一
- Journal Title
  
  リウマチ科 31(2)
  
  Pages: 199-205
- Data Source
  KAKENHI-PROJECT-15790791
[Journal Article] 軟骨細胞保護におけるIL-4の役割2004
- Author(s)
  西田圭一郎, 依光正則, 土井英之, 井上一, 清水晃
- Journal Title
  
  臨床免疫 41(5)
  
  Pages: 551-555
- Data Source
  KAKENHI-PROJECT-15790791
[Presentation] 細胞外小胞の軟骨細胞と滑膜細胞への取り込み検討2024
- Author(s)
  高下蓮、池村健太郎、Opoku Gabriel、平林沙江子、井口和香、Farhana Hasib、佐藤生弥、古松毅之、西田圭一郎、安藤満、秋吉一成、廣畑聡
- Organizer
  第36回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20H00548
[Presentation] HEK-293由来細胞外小胞の軟骨細胞と滑膜細胞への取り込みの検討2023
- Author(s)
  高下蓮、池村健太郎、Opoku Gabriel、鶴川しほろ、平林沙江子、井口和香、Farhana Hasib、佐藤生弥、古松毅之、西田圭一郎、安藤満、秋吉一成、廣畑聡
- Organizer
  第55回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-20H00548
[Presentation] NF-κBを介したCEMIP発現誘導の解析2020
- Author(s)
  兒玉慎太郎、大月孝志、オメル・F・ハティポ-ル、池村健太郎、安藤亮典、中野愛梨、畑本早紀子、立木美穂、ガブリエルオポク、稲垣純子、西田圭一郎、廣畑聡
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H00548
[Presentation] Anti-CD30 immunotherapy ameliorates bone and cartilage destruction in experimental model of rheumatoid arthritis in mice2020
- Author(s)
  Matsuhashi M, Nishida K, Nasu Y, Nakahara R, Watanabe M, Hotta Y, Ozaki T
- Organizer
  EULAR 2020
- Data Source
  KAKENHI-PROJECT-20K09433
[Presentation] 軟骨様細胞OUMS-27におけるCEMIP誘導並びに制御機構2020
- Author(s)
  兒玉慎太郎、大月孝志、オメル・F・ハティポ-ル、立木美穂、ガブリエルオポク、稲垣純子、西田圭一郎、廣畑聡
- Organizer
  第52回日本結合組織会学術大会
- Data Source
  KAKENHI-PROJECT-20H00548
[Presentation] 変形性関節症に有効な新規化合物の探索2020
- Author(s)
  中野愛梨、稲垣純子、大月孝志、兒玉慎太郎、オメル・F・ハティポ-ル、池村健太郎、安藤亮典、畑本早紀子、立木美穂、ガブリエルオポク、西田圭一郎、廣畑聡
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H00548
[Presentation] CD 30 をターゲットとした新規リウマチ治療の検討2020
- Author(s)
  松橋　美波、西田　圭一郎、渡辺　雅仁、木曽　洋平、中原　龍一、那須　義久、尾﨑　敏文
- Organizer
  第93回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09433
[Presentation] 変形性関節症に有効な新規化合物の探索2020
- Author(s)
  中野愛梨、稲垣純子、大月孝志、兒玉慎太郎、オメル・F・ハティポ-ル、池村健太郎、安藤亮典、畑本早紀子、立木美穂、ガブリエルオポク、西田圭一郎、廣畑聡
- Organizer
  第93回日本生化学会大会(WEB開催)
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] CD 30をターゲットとした関節リウマチ新規治療の検討2020
- Author(s)
  松橋　美波、西田　圭一郎、渡辺　雅仁、木曽　洋平、中原　龍一、那須　義久、尾﨑　敏文
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K09433
[Presentation] NF-κBを介したCEMIP発現誘導の解析2020
- Author(s)
  兒玉慎太郎、大月孝志、オメル・F・ハティポ-ル、池村健太郎、安藤亮典、中野愛梨、畑本早紀子、立木美穂、ガブリエルオポク、稲垣純子、西田圭一郎、廣畑聡
- Organizer
  第93回日本生化学会大会(WEB開催)
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] 軟骨細胞産生エクソソームの軟骨細胞への取り込み機構の解析2019
- Author(s)
  兒玉慎太郎、Wanyu Yan、劉国楽、大月孝志、オメル・ファルク・ハティポール、西村拓人、立木美穂、稲垣純子、山田浩司、古松毅之、西田圭一郎、廣畑　聡
- Organizer
  Brainstorming-2019 at Carillon House
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] Analysis of exosome uptake by chondrocyte2019
- Author(s)
  Shitaro Kodama, Yan Wanyu, Liu Guole, Takashi Ohtsuki, Omer Faruk Hatipoglu, Takuto Nishimura, Miho Tatiki, Junko Inagaki, Hiroshi Yamada, Keiichiro Nishida, Sun Liankun, Satoshi Hirohata
- Organizer
  Brainstorming 2019
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] IL-1 beta treatment up-regulated CD9 in exosome and chondrocyte2019
- Author(s)
  Wanyu Yan, Shintaro Kodama, Guole Liu, Takashi Ohtsuki, Omer Faruk Hatipoglu, Takuto Nishimura, Miho Tachiki, Junko Inagaki, Hiroshi Yamada, Takayuki Firumatsu, Keiichiro Nishida, Liankun Sun, Satoshi Hirohata
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] メカニカルストレスによるHYBID遺伝子の発現抑制2019
- Author(s)
  大月　孝志、劉　国楽、西村　拓人、立木　美穂、岡田　真澄、品岡　玲、チレッキ　メフメット、オメル　ハティポール、稲垣　純子、古松　毅之、西田　圭一郎、下田　将之、岡田　保典、廣畑　聡
- Organizer
  第32回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] Isolation and characterization of extracellular microvesicles in osteoarthritis2019
- Author(s)
  Liu Guole, Takashi Ohtsuki, Akira Shinaoka, Kana Komatsu, Yurika Notsu, Omer Faruk Hatipoglu, Takuto Nishimur, Miho Tatii, Junko Inagaki, Hiroshi Yamada, Keiichiro Nishida, Sun Liankun, Satoshi Hirohata
- Organizer
  The 32th Annual meeting of the Japanese Society of Cartilage metabolism
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] IL-1beta treatment up-regulated CD9 in exosome and chondrocyte2019
- Author(s)
  Yan Wanyu, Shintaro Kodama, Liu Guole, Takashi Ohtsuki, Omer Faruk Hatipoglu, Takuto Nishimura, Miho Tachiki, Junko Inagaki, Hiroshi Yamada, Takayuki Furumatsu, Keiichiro Nishida, Liankun Sun, Satoshi Hirohata
- Organizer
  The 42nd Annual Meeting of the molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] Cartilage matrix regeneration by understanding miRNA and Exosomes2019
- Author(s)
  Takashi Ohtsuki, Yan Wanyu, Shintaro Kodama, Liu Guole, Omer Faruk Hatipoglu, Junko Inagaki, Ken Takahashi, Hiroshi Yamada, Toshitaka Ohashi, Takayuki Furumatsu, Keiichiro Nishida, Yasunori Okada, Suneel S, Apte, Satoshi Hirohata
- Organizer
  Brainstorming 2019
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] CD9 antibody treated Extracellular Vesicles reduced uptake by chondrocyte2019
- Author(s)
  Takashi Ohtsuki, Yan Wanyu, Shintaro Kodama, Liu Guole, Omer Faruk Hatipoglu, Junko Inagaki, Hiroshi Yamada, Takayuki Furumatsu, Keiichiro Nishida, Satoshi Hirohata
- Organizer
  Japanese Society for Extracellular Vesiles 6th annual meeting
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] Isolation and characterization of OA related extracellular vesicles2019
- Author(s)
  Takashi Ohtsuki, Shintaro Kodama, Yan Wanyu, Liu Guole, Omer Faruk Hatipoglu, Takuto Nishimura, Miho Tachiki, Junko Inagaki, Hiroshi Yamada, Takayuki Furumatsu, Keiichiro Nishida, Satoshi Hirohata
- Organizer
  11th Annual Meeting of the Japan CCN family study group
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] Characterization and uptake mechanism of OA related extracellular vesicles2019
- Author(s)
  Takashi Ohtsuki, Yan Wanyu, Shintaro Kodama, Liu Guole, Omer Faruk Hatipoglu, Junko Inagaki, Hiroshi Yamada, Takayuki Furumatsu, Keiichiro Nishida, Satoshi Hirohata
- Organizer
  The First International Symposium for Intercellular Communication and Extracellular Vesicles I
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09627
[Presentation] Isolation and characterization of Osteoarthritis concerning microRNA2018
- Author(s)
  Takashi Ohtsuki, Omer Faruk Hatipoglu, Akira Shinaoka, Mehmet Zeynel Cilek, Takuto Nishimura, Keiichi Asano, Junko Inagaki, Toshitaka Oohashi, Keiichiro Nishida, Yasunori Okada, Satoshi Hirohata
- Organizer
  Joint Conference of 50th Annual Meeting of the Japanese Society of Connective Tissue Research (JSCTR)
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] Isolation and characterization of extracellular microvesicles in osteoarthritis2018
- Author(s)
  Liu Guole, Takashi Ohtsuki, Akira Shinaoka, Kana Komatsu, Yurika Notsu, Omer Faruk Hatipoglu, Takuto Nishimur, Miho Tatii, Junko Inagaki, Hiroshi Yamada, Keiichiro Nishida, Sun Liankun, Satoshi Hirohata
- Organizer
  The 41st Annual Meeting of the molecular Biology Society of Japan
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] Analysis of cartilage matrix degradation and regeneration mechanism2018
- Author(s)
  Takashi Ohtsuki, Liu Guole, Omer Faruk Hatipoglu, Akira Shinaoka, Junko Inagaki, Ken Takahashi, Hiroshi Yamada, Toshitaka Ohashi, Keiichiro Nishida, Yasunori Okada, Suneel S, Apte, Satoshi Hirohata
- Organizer
  Brainstorming 2018
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] Isolation and characterization of extracellular microvesicles in osteoarthritis2018
- Author(s)
  Liu G, Ohtsuki T, Shinaoka A, Komatsu K, Notsu Y, Hatipoglu OF, Nishimura T, Inagaki J, Yamada H, Nishida K, Sun L, Hirohata S.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] Mechanical stress attenuated inflammatory cytokines induced matrix degradative enzymes expression in chondrocyte by inhibition of NF-kB translocation2018
- Author(s)
  Takashi Ohtsuki, Omer Faruk Hatipoglu, Guole Liu, Akira Shinaoka, Keiichi Asano, Takuto Nishimura, Junko Inagaki, Keiichiro Nishida, Toshitaka　Oohashi, Satoshi Hirohata
- Organizer
  American Society for Matrix Biology Biennial Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] Purification and characterization of exosome from chondrocyte conditioned medium and analysis of exosome up-taking mechanism in chondrocyte2018
- Author(s)
  Liu Guole, Takashi Ohtsuki, Akira Shinaoka, Kana Komatsu, Yurika Notsu, Omer Faruk Hatipoglu, Takuto Nishimura1, Miho Tatiki, Junko Inagaki, Hiroshi Yamada, Keiichiro Nishida, Sun Liankun, Satoshi Hirohata
- Organizer
  Brainstorming 2018
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] Isolation and characterization of matrix degradative microRNA2018
- Author(s)
  Takashi Ohtsuki, Omer Faruk Hatipoglu, Akira Shinaoka, Mehmet Zeynel Cilek, Takuto Nishimura, Keiichi Asano, Junko Inagaki, Toshitaka Oohashi, Keiichiro Nishida, Yasunori Okada, Satoshi Hirohata
- Organizer
  10th Annual Meeting of the Japan CCN family study group
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] ADAM12はRUNX2を介した軟骨細胞肥大化の制御に重要である2018
- Author(s)
  堀田昌宏、西田圭一郎、長谷井嬢、古松毅之、尾﨑敏文
- Organizer
  第36回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-17K11010
[Presentation] Molecular and biochemical analysis of HYBID (HYaluronan-Binding protein Involved in hyaluronan Depolymerization) gene expression2017
- Author(s)
  Ohtsuki T, Yoshida H, Shinaoka A, Kumagishi-Shinaoka K, Cilek MZ, Hatipoglu OF, Inagaki J, Nishida K,Okada Y, Hirohata S.
- Organizer
  第30回日本軟骨代謝学会
- Place of Presentation
  京都市
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] 軟骨分化制御による骨棘形成過程へのADAM12の関与2017
- Author(s)
  堀田昌宏, 西田圭一郎, 長谷井嬢, 古松毅之, 宮澤慎一, 那須義久, 中原龍一, 竹下歩, 兼田大輔, 大橋秀基, 尾﨑敏文
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11010
[Presentation] 炎症性サイトカイン誘導性マトリックス分解酵素発現のイオンチャネルを介した抑制とその機構解析　Inflammatory cytokine-induced matrix degrading enzymes expression were　attenuated by mechanical stress through transient receptor potential cation　channel2017
- Author(s)
  大月孝志、品岡玲、品岡加苗、Cilek Mehmet、Hatipoglu Omer、西村拓人、稲垣純子、西田圭一郎、廣畑聡
- Organizer
  2017 年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] INFLAMMATORY CYTOKINE INDUCED HYBID (HYALURONAN-BINDING PROTEIN INVOLVED IN HYALURONAN DEPOLYMERAZATION)　-EXPRESSION MECHANISM-2017
- Author(s)
  Takashi Ohtsuki, Lyu Chen, Hiroyuki Yoshida, Akira Shinaoka, Kanae Kumagishi-Shinaoka, Mehmet Zeynel Cilek, Omer Faruk Hatipoglu, Junko Inagaki, Keiichiro Nishida, Yasunori Okada, Satoshi Hirohata
- Organizer
  HYALRONAN 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] メカニカルストレスの軟骨細胞に及ぼす多彩な作用-マトリックス合成促進と炎症性サイトカイン誘導性マトリックス分解活性抑制2017
- Author(s)
  大月孝志、品岡玲、熊岸-品岡加苗、メフメット・ゼイネル・チレッキ、オメル・ファルク・ハティポール、稲垣純子、西田圭一郎、廣畑　聡
- Organizer
  第49回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] 変形性関節症における骨棘形成へのmiR-29bを介したADAM12の関与2017
- Author(s)
  堀田昌宏, 西田圭一郎, 長谷井嬢, 古松毅之, 宮澤慎一, 那須義久,中原龍一,竹下歩, 兼田大輔, 櫻井美和, 国定俊之, 尾﨑敏文
- Organizer
  第30回日本軟骨代謝学会
- Place of Presentation
  京都市
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-26462299
[Presentation] メカニカルストレスの軟骨細胞に及ぼす多彩な作用-マトリックス合成促進と炎症性サイトカイン誘導性マトリックス分解活性抑制2017
- Author(s)
  大月孝志、品岡玲、熊岸-品岡加苗、メフメット・ゼイネル・チレッ、オメル・ファルク・ハティポール、稲垣純子、西田圭一郎、廣畑聡
- Organizer
  第49回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] HYBID (HYaluronan-Binding protein Involved in hyaluronan Depolymerization)　遺伝子の炎症性サイトカインによる発現機構解析2017
- Author(s)
  大月孝志、吉田浩之、品岡玲、熊岸-品岡加苗、メフメット・ゼイネル・チレッキ、オメル・ファルク・ハティポール、稲垣純子、西田圭一郎、岡田保典、廣畑聡 "
- Organizer
  第30回日本軟骨代謝学会
- Place of Presentation
  京都
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] 炎症性サイトカイン誘導性マトリックス分解酵素発現のイオンチャネルを介した抑制機構解析2017
- Author(s)
  大月孝志、品岡玲、熊岸-品岡加苗、オメル・ファルク・ハティポール、山之口奈保、岡田真澄、西村拓人、稲垣純子、西田圭一郎、廣畑聡
- Organizer
  第40回日本分子生物学会年会　第90回日本生化学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] Inflammatory cytokine induced HYBID (HYALURONAN-BINDING PROTEIN INVOLVED IN HYALURONAN DEPOLYMERAZATION) -Expression mechanism-2017
- Author(s)
  Takashi Ohtsuki, Lyu Chen, Hiroyuki Yoshida, Akira Shinaoka, Kanae Kmagishi-Shinaoka, Mehmet Zeynel Cilek, Omer Faruk Hatipoglu, Junko Inagaki, Keiichiro Nishida, Yasunori Okada, Satoshi Hirohata
- Organizer
  HA2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04313
[Presentation] 変形性関節症における骨棘形成に対するADAM12の関与2016
- Author(s)
  堀田昌宏, 西田圭一郎, 古松毅之, 宮澤慎一, 那須義久, 藤原智洋, 中原龍一, 町田崇博, 竹下歩, 兼田大輔, 尾﨑敏文
- Organizer
  第31回日本整形外科基礎学術集会
- Place of Presentation
  福岡県博多市
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26462299
[Presentation] ラット変形性関節症モデルへのヒアルロン酸投与による軟骨保護効果の解析2016
- Author(s)
  大月孝志、品岡玲、熊岸加苗、佐藤未來、金道幸子、長谷川みさ、海原弘貴、浅野恵一、障子友理、稲垣純子、大橋俊孝、西田圭一郎、廣畑聡
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島（広仁会館）
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] Assesment of therapeutic value of osteoarthritis rehabilitation by molecular biological and biochemical approach2016
- Author(s)
  Takashi Ohtsuki1, Kanae Kumagishi24, Akira Shinaoka2, Keiichiro Nishida2, Aiji Ootsuka2, Kenichiro Sakata3, Syunsuke Sakata3, Kenji Kawamura4, Satoshi Hirohata1
- Organizer
  第2回国際リハビリテーションシンポジウムin京都
- Place of Presentation
  京都大学（杉浦地域医療研究センター）
- Year and Date
  2016-03-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] 変形性関節症へのヒアルロン酸投与、いつ投与すべきか？～動物モデルからの知見～2016
- Author(s)
  大月孝志、品岡　玲、熊岸香苗、河野真優美、篠原真歩、浅野恵一、稲垣純子、大橋俊孝、西田圭一郎、廣畑　聡
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎市
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] 変形性関節症へのヒアルロン酸投与、いつ投与すべきか？～動物モデルからの知見～2016
- Author(s)
  大月孝志、品岡玲、熊岸加苗、河野真優美、篠原真歩、浅野恵一、稲垣純子、大橋俊孝、西田圭一郎、廣畑聡
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K10905
[Presentation] ラット変形性関節症モデルへのヒアルロン酸投与による軟骨保護効果の解析2016
- Author(s)
  大月孝志、品岡玲、熊岸加苗、佐藤美來、金道幸子、長谷川みさ、海原弘貴、浅野恵一、障子友理、稲垣純子、大橋俊孝、西田圭一郎、廣畑　聡
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島市
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] HYALURONAN TREATMENT REDUCED MATRIX DEGRADATION BOTH IN VITRO AND IN VIVO RAT OSTEOARTHRITIS MODEL.2015
- Author(s)
  Takashi Ohtsuki, , Yuri Shoji, Keiichi Asano, Aya Hirata, Teruyuki Kawadi, Junko Ingaki, Kanae Kumagishi, Keiichiro Nishida, Toshitaka　Oohashi ,Satoshi Hirohata
- Organizer
  10th International Confewrence HYALURONAN 2015
- Place of Presentation
  Florence (Italy)
- Year and Date
  2015-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] 伸展刺激の強度による細胞外マトリックスタンパクおよびマトリックス分解酵素発現への影響2015
- Author(s)
  大月孝志、金道幸子、長谷川みさ、稲垣純子、浅野恵一、障子友理、熊岸加苗、西田圭一郎、大橋俊孝、廣畑　聡
- Organizer
  第38回分子生物学会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸（神戸ポートピアアイランド）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] Moderate mechanical stress differently altered the mRNA expressions of aggrecan, collagen and ADAMTSs in human chondrosarcoma cells.2015
- Author(s)
  Takashi Ohtsuki, Yukiko Kindo, Misa hasegawa, Aya Hirata, Teruyuki Kawadi, Keiichi Asano, Junko Inagaki, Shoji Yuri, Kanae Kumagishi, Keiichiro Nishida, Toshitaka Oohashi, Satoshi Hirohata,
- Organizer
  Joint Conference of 47th Annual Meeting of the Japanese Society of Connective Tissue Research (JSCTR)
- Place of Presentation
  Tokyo（KOKUYO hall ）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] A feasible study of molecular bio-imaging of articular cartilage proteoglycans2015
- Author(s)
  "Toshitaka Oohashi, Hiroki Kakuta，Manabu Hagaya, Satoshi Hirohata，Shoya Yamada, Yoshifumi Ninomiya，Keiichiro Nishida"
- Organizer
  Joint Conference of 47th Annual Meeting of the Japanese Society of Connective Tissue Research (JSCTR)
- Place of Presentation
  Tokyo（KOKUYO hall ）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] 伸展刺激の強度による細胞外マトリックスタンパクおよびマトリックス分解酵素発現への影響2015
- Author(s)
  大月孝志、金道幸子、長谷川みさ、稲垣純子、浅野恵一、障子友理、熊岸加苗、西田圭一郎、大橋俊孝、廣畑　聡
- Organizer
  BMB 2015
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] HYALURONAN TREATMENT REDUCED MATRIX DEGRADATION BOTH IN VITRO AND IN VIVO RAT OSTEOARTHRITIS MODEL2015
- Author(s)
  Yuri Shoji, Keiichi Asano, Aya Hirata, Teruyuki Kawadi, Junko Ingaki, Kanae Kumagishi, Keiichiro Nishida, Toshitaka Oohashi, Satoshi Hirohata.
- Organizer
  10th International conference HYALURONAN 2015
- Place of Presentation
  イタリア・フィレンツェ
- Year and Date
  2015-06-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] メカニカルストレスに対するJAK阻害薬Tofacitinibの軟骨破壊抑制効果2015
- Author(s)
  町田崇博、西田圭一郎、那須義久、中原龍一、堀田昌宏、竹下歩、兼田大輔、尾﨑敏文
- Organizer
  第26回日本リウマチ学会中国・四国支部学術集会
- Place of Presentation
  岡山市
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26462299
[Presentation] メカニカルストレスに対するJAK阻害薬Tofacitinibの軟骨破壊抑制効果2015
- Author(s)
  町田崇博、西田圭一郎、那須義久、中原龍一、斎藤太一、堀田昌宏、竹下歩、兼田大輔、尾﨑敏文
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山市
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26462299
[Presentation] Short period Hyaluronan treatment reduced cartilage degradation in rat osteoarthritis model.2014
- Author(s)
  Takashi Ohtsuki, Satoshi Hirohata, Yuri Shoji, Keiichi Asano, Aya Hirata, Teruyuki Kawadi, Junko Ingaki, Kanae Kumagishi, Keiichiro Nishida, Yoshifumi Ninomiya
- Organizer
  Joint Conference of 46th Annual Meeting of the Japanese Society of Connective Tissue Research (JSCTR), and 61th Annual Meeting of the Japan Matrix Club (JMC)
- Place of Presentation
  Nagoya（Wink Nagoya）
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] Creation of novel articular cartilage specific X-ray imaging probes composed of lysine oligomers2014
- Author(s)
  Toshitaka Oohashi, Manabu Hagaya, Mitsuaki Ono, Shoya Yamada, Takashi Ohtsuki, Ami Maehara, Satoshi Hirohata, Keiichiro Nishida, Takuo Kuboki, Hiroki Kakuta, Yoshifumu Ninomiya
- Organizer
  The 27th Annual meeting of the Japanese Society of Cartilage metabolism
- Place of Presentation
  (Kyoto) Kyoto Medical Association Center
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] Cyclic tensile strain (CTS) down-regulates interleukin(IL)-1b and Tumor necrosis factor(TNF)-a induced matrix degrading enzymes mRNA expression in human chondrosarcoma cell line OUMS-27 by mechano sensor2014
- Author(s)
  Takashi Ohtsuki, Teruyuki　Kawadi,　Aya Hirata, Keiichi Asano, Eriko Kusunoki , Junko Inagaki, Kanae Kumagishi , Keiichiro Nishida ,　Yoshifumi Ninomiya , Satoshi Hirohata
- Organizer
  The 2nd International Symposium on Mechanobiology (ISMB 2014)
- Place of Presentation
  Okayama(Okayama university Junko Fukutake Hall)
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] リジンオリゴマーからなる関節軟骨特異的X線プローブの創出2014
- Author(s)
  大橋俊孝、芳谷　学、大野充昭、山田翔也、大月孝志、前原亜美、廣畑　聡、西田圭一郎、窪木拓男、加来田博貴、二宮善文
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] リジンオリゴマープローブからなる関節軟骨特異的X線プローブの創出2014
- Author(s)
  大橋俊孝、芳谷学、大野充昭、山田翔也、大月孝志、前原亜美、廣畑聡、西田圭一郎、窪木拓男、加来田博貴、二宮善文
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都府医師会館
- Data Source
  KAKENHI-PROJECT-25670648
[Presentation] リジンオリゴマーからなる関節軟骨特異的X 線プローブの創出2014
- Author(s)
  大橋俊孝, 芳谷学, 大野充昭, 山田翔也, 大月孝志, 前原亜美, 廣畑聡, 西田圭一郎, 窪木拓男, 加来田博貴, 二宮善文
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Structurally simple cartilage probes constructed with ε-lysine oligomers targeting chondroitin sulfates2014
- Author(s)
  Hiroki Kakuta, Manabu Hagaya, Shoya Yamada, Yuki Furusawa, Ami Maehara, Satoshi Hirohata, Keiichiro Nishida, Mitsuaki Ono, Takashi Ohtsuki, Yoshifumi Ninomiya, and Toshitaka Oohashi
- Organizer
  第7回高度医療都市を創出する未来技術国際シンポジウム
- Place of Presentation
  Okayama 　Okayama university
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] ヒアルロン酸の炎症性サイトカイン誘導性ヒアルロン酸合成酵素分子種への影響2014
- Author(s)
  大月孝志, 廣畑聡, 平田彩, 浅野恵一, 楠絵里子, 稲垣純子, 西田圭一郎, 二宮善文
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Hyaluronan protects articular cartilage in a size dependent manner (in vivo and in vitro study)2013
- Author(s)
  Takashi Ohtsuki, Omer Faruk Hatipoglu, Keiichiro Nishida , Satoshi Hirohata ,　Yoshifumi Ninomiya
- Organizer
  Joint Conference of 45th Annual Meeting of the Japanese Society of Connective Tissue Research (JSCTR), and 60th Annual Meeting of the Japan Matrix Club (JMC)
- Place of Presentation
  Wakayama（Wakayama Univ. Lifelong Learing and Medical Community Center）
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] ヒアルロン酸(HA)分子量と関節軟骨保護効果の解析（in vitro & in vivo）2013
- Author(s)
  大月孝志　廣畑　聡　浅野恵一　楠絵里子　稲垣純子　西田圭一郎　二宮善文
- Organizer
  第４５回日本結合組織学会学術大会　第６０回マトリックス研究会大会
- Place of Presentation
  和歌山県和歌山市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] ヒアルロン酸(HA)分子量と関節軟骨保護効果の解析(in vitro & in vivo)2013
- Author(s)
  大月孝志, 廣畑聡, 浅野恵一, 楠絵里子, 稲垣純子, 西田圭一郎, 二宮善文
- Organizer
  第45回日本結合組織学会学術大会第60回マトリックス研究会大会
- Place of Presentation
  和歌山市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Cyclic tensile strain (CTS) inhibits Interleukin-1beta and Tumor Necrosis Factor-alpha induced catalytic reactions in human chondrosarcoma cell line OUMS-27-microRNA array analysis-2013
- Author(s)
  Takashi Ohtsuki, Teruyuki　Kawadi,　Aya Hirata, Keiichi Asano, Eriko Kusunoki , Junko Inagaki, Kanae Kumagishi , Keiichiro Nishida ,　Yoshifumi Ninomiya , Satoshi Hirohata
- Organizer
  The 36th Annual meeting of the Molecular Biology Society of Japan
- Place of Presentation
  (Kobe) Kobe Conbention Center
- Data Source
  KAKENHI-PROJECT-25462372
[Presentation] Cyclic tensile strain(CTS)による炎症性サイトカイン誘導性細胞応答に対する抑制機構 micro RNA array による解析2013
- Author(s)
  大月孝志, 川地輝幸, 平田彩, 浅野恵一, 楠絵理子, 稲垣純子, 熊岸加苗, 西田圭一郎, 二宮善文, 廣畑聡
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Cyclic tensile strain (CTS) による炎症性サイトカイン誘導性ADAMTS ファミリー発現抑制機構へのメカノセンサーの関与2013
- Author(s)
  大月孝志, 廣畑聡, 西田圭一郎, 二宮善文
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] メカニカルストレスとサイトカイン2012
- Author(s)
  大月孝志, 廣畑聡, 西田圭一郎, 二宮善文
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Cyclic tensile strain inhibits Interleukin-1β and Tumor Necrosis Factor-αinduced aggrecanase in human chondrosarcoma cell line OUMS-27.2012
- Author(s)
  大月孝志(代表)、西田圭一郎、廣畑聡、二宮善文
- Organizer
  第25回日本軟骨代謝学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591687
[Presentation] ヒアルロン酸(HA)分子量と関節軟骨保護効果の解析2012
- Author(s)
  大月孝志, メフメット・ゼイネル・チレッキ, ハティポール・オメル・ファルク, 西田圭一郎, 二宮善文, 廣畑聡
- Organizer
  第44回日本結合組織学会学術大会第59回マトリックス研究会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] 関節炎モデルマウスに対するヒストン脱アセチル化酵素1(HDAC1) siRNAの治療効果の検討2012
- Author(s)
  金澤智子、西田圭一郎、松本衣未、大橋俊孝、二宮善文、古松　毅之、尾﨑敏文
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23592215
[Presentation] Cyclic tensile strain inhibits Interleukin-1β and Tumor Necrosis Factor-α induced aggrecanase in human chondrosarcoma cell line OUMS-27 by mechano-sensors.2012
- Author(s)
  大月孝志(代表)、西田圭一郎、廣畑聡、二宮善文
- Organizer
  第26回日本軟骨代謝学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22591687
[Presentation] Hyaluronan size dependent articular cartilage protection effect (in vivo and in vitro study)2012
- Author(s)
  大月孝志(代表)、Mehmet Z. Cilek、O.F. Hatipoglu、西田圭一郎、二宮善文、廣畑聡
- Organizer
  第44回日本結合組織学会学術大会第59回マトリックス研究会大会合同学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591687
[Presentation] ADAMTS1 inhibit angiogenesis :in vitro and in vivo study2012
- Author(s)
  大月孝志(代表)、Mehmet Z. Cilek、O.F. Hatipoglu、西田圭一郎、二宮善文、廣畑聡
- Organizer
  ASMB 2012 Joint Meeting of the American Society for Matrix Biology and the Society for Glycobiology
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-22591687
[Presentation] Cyclic tensile strain inhibits Interleukin-1β and Tumor Necrosis Factor-α induced aggrecanase in human chondrosarcoma cell line OUMS-27 by stretch-activated channels2012
- Author(s)
  Ohtsuki T, Nishida K, Hirohata S, Ninomiya Y
- Organizer
  2012 Biennial Meeting of American Society for Matrix Biology
- Place of Presentation
  米国 San Diego
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Hyaluronan inhibits aggrecanase in human chondrosarcoma cell line OUMS-27 in a size dependent manner2011
- Author(s)
  Ohtsuki T, Nishida K, Hirohata S, Ninomiya Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23390366
[Presentation] Hyaluronan inhibits aggrecanase in human chondrosarcoma cell line OUMS-27 in a size dependent manner.2011
- Author(s)
  大月孝志(代表)、西田圭一郎、廣畑聡、二宮善文
- Organizer
  第24回日本軟骨代謝学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591687
[Presentation] Hyaluronan inhibits aggrecanase in human chondrosarcoma cell line OUMS-27 in a size dependent manner.2011
- Author(s)
  大月孝志(代表)、西田圭一郎、廣畑聡、二宮善文
- Organizer
  第34回日本分子生物学会年会第86回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591687
[Presentation] ヒト軟骨細胞様細胞においてADAMTS-5はRUNX-2を介してメンカノセンシティブに機能するアグリカナーゼである2010
- Author(s)
  鉄永智紀, 西田圭一郎, 古松毅之, 斎藤太一, 成瀬恵治, 尾崎敏文
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  京都府
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] 軟骨細胞様細胞における力学的負荷誘導性のRunx2およびMMP-13, ADAMTS-5の発現2009
- Author(s)
  鉄永智紀, 西田圭一郎, 古松毅之, 米澤朋子, 二宮善文, 成瀬恵治, 尾崎敏文
- Organizer
  第22回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] 軟骨細胞様細胞における力学的負荷誘導性のRunx2およびMMPべ3, ADAMTS-5の発現2009
- Author(s)
  鉄永智紀, 西田圭一郎, 尾崎敏文
- Organizer
  第22回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] ヒト軟骨細胞様細胞における力学的負荷誘導性のRUNX2およびMMP-13, ADAMTS-5発現の検討2009
- Author(s)
  鉄永智紀, 西田圭一郎, 古松毅之, 吉田晶, 国定俊之, 成瀬恵治, 三谷茂, 尾崎敏文
- Organizer
  第24回日本整形外科学会基礎学術集会
- Place of Presentation
  横浜市
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] 軟骨細胞様細胞(OUMS-27)に対するメカニカルストレスによるRunx2および蛋白分解酵素の発現2008
- Author(s)
  鉄永智紀, 西田圭一郎, 門田康孝
- Organizer
  第52回日本リウマチ学会総会・学術集会
- Place of Presentation
  札幌市
- Year and Date
  2008-04-23
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] 軟骨細胞様細胞においてIL-4は力学的負荷誘導性のCbfa1/Runx2およびMMP-13, ADAMTS-5の発現を抑制する2008
- Author(s)
  鉄永智紀, 西田圭一郎, 古松毅之, 吉田晶, 国定俊之, 成瀬恵治, 尾崎敏文
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都府
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] 軟骨細胞様細胞においてIL-4は力学的負荷誘導性のCbfal/Runx2およびMMP-13, ADAMTS-5の発現を抑制する2008
- Author(s)
  鉄永智紀, 西田圭一郎, 尾崎敏文
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20591780
[Presentation] ヒアルロン酸短期投与によるラット変形性関節症モデルの関節軟骨保護効果の検討
- Author(s)
  大月孝志、廣畑聡、障子友理、浅野恵一、平田彩、川地輝幸、稲垣純子、熊岸加苗、西田圭一郎、二宮善文
- Organizer
  第46回日本結合組織学会学術大会　第61回マトリックス研究会大会
- Place of Presentation
  名古屋市
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] 新規X線造影剤による変形性膝関節症ラット関節軟骨の高解像度マイクロＣＴ造影
- Author(s)
  大橋俊孝、加来田博貴、芳谷　学、大月孝志、大野充昭、山田翔也、前原亜美、廣畑　聡、西田圭一郎、窪木拓男、二宮善文
- Organizer
  第46回日本結合組織学会学術大会　第61回マトリックス研究会大会
- Place of Presentation
  名古屋市
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] HYALURONAN REDUCED EXTRACELLULAR MATRIX DEGRADATION BOTH IN VITRO AND IN VIVO
- Author(s)
  Takashi Ohtsuki, Yuri Shoji, Keiichi Asano, Aya Hirata, Teruyuki Kawadi, Junko Ingaki, Kanae Kumagishi, Keiichiro Nishida, Toshitaka Oohashi, Satoshi Hirohata.
- Organizer
  HA2015
- Place of Presentation
  フィレンツェ
- Year and Date
  2015-06-07 – 2015-06-11
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] Creation of Novel Articular Cartilage Specific X-ray Imaging Probes Composed of Lysine Oligomers.
- Author(s)
  Oohashi T, Hagaya M, Ono M, Yamada S, Ohtsuki T, Maehara A, Hirohata S, Nishida K, Kuboki T, Kakuta H, NinomiyaY.
- Organizer
  International symposium on mechanobiology 2014
- Place of Presentation
  岡山市
- Year and Date
  2014-05-20 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] Decreased Sox9 mRNA expression by cytokine stimulation was ameliorated by hyaluronan in chondrosarcoma cells
- Author(s)
  Takashi Ohtsuki, Satoshi Hirohata, Yuri Shoji, Keiichi Asano, Aya Hirata, Teruyuki Kawadi, Junko Ingaki, Kanae Kumagishi, Keiichiro Nishida, Toshitaka　Oohashi, Aiji Ohtsuka
- Organizer
  American Society for Matrix Biology Biennial Meeting
- Place of Presentation
  米国　クリーブランド
- Year and Date
  2014-10-12 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-26293338
[Presentation] 新規X線造影剤による変形性膝関節症ラット関節軟骨の高解像度マイクロCT造影
- Author(s)
  大橋俊孝、加来田博貴、芳谷学、大月孝志、大野充昭、山田翔也、前原亜美、廣畑聡、西田圭一郎、窪木拓男、二宮善文
- Organizer
  第46回日本結合組織学会
- Place of Presentation
  ウインクあいち
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25670648
[Presentation] Cyclic tensile strain (CTS) down-regulates interleukin(IL)-1β and Tumor necrosis factor(TNF)-α induced matrix degrading enzymes mRNA expression in human chondrosarcoma cell line OUMS-27 by mechano sensor.
- Author(s)
  Ohtsuki T, Kawadi T, Hirata A, Asano K, Inagaki J, Kumagishi K, Nishida K, Ninomiya Y, Hirohata S
- Organizer
  International symposium on mechanobiology 2014
- Place of Presentation
  岡山市
- Year and Date
  2014-05-20 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26293338

1. HIROHATA Satoshi (90332791)

# of Collaborated Projects: 17 results

# of Collaborated Products: 80 results
2. OHTSUKI Takashi (10534802)

# of Collaborated Projects: 10 results

# of Collaborated Products: 72 results
3. NINOMIYA Yoshifumi (70126241)

# of Collaborated Projects: 10 results

# of Collaborated Products: 30 results
4. OOHASHI Toshitaka (50194262)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
5. NARUSE Keiji (40252233)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
6. 古松毅之 (20432651)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
7. YONEZAWA Tomoko (30304299)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OGAWA Hiroko (70423283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KAWABATA Tomoko (90600669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KAKUTA Hiroki (80362961)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. Hatipoglu Omer Faruk (90791765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. 井上一 (70033206)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 冨田秀太 (10372111)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 渡辺彰吾 (20548341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 岡田保典 (00115221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 落谷孝広 (60192530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 西中崇 (50786184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 高橋英夫 (60335627)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 和氣秀徳 (60570520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 鉄永智紀 (90571224)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
21. KOMATSU Naoki (30253008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Fujibuchi Wataru (60273512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Shinohata Ryoko (70335587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Kusachi Shozo (30214943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 川井章 (90252965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 大塚愛二 (50168986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 阿部信寛 (80284115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 吉鷹輝仁 (20397897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 伊藤佐智夫 (30335624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 品岡玲 (90724500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
31. 大野充昭 (60613156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 佐藤康晴 (00579831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 鉄永倫子 (70601384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 佐藤生弥 (10975361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. ASZDI Attila

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 吉田晶

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
37. 尾崎敏文

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
38. 稲垣純子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 中村一文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 赤木達

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 鵜殿平一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NISHIDA Keiichiro 西田 圭一郎

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of hyaluronan-degrading enzyme HYBID expression by chondrocytes and its regulation by microRNAsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CD30 targeted therapy induces apoptosis of inflammatory cytokine-stimulated synovial fibroblasts and ameliorates collagen antibody-induced arthritis in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory system of microRNA and ADAM12 expression in the process of joint remodelingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetic regulation of miRNA induced by mechanical stress in human chondrocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

NISHIDA Keiichiro 西田圭一郎