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MARUSAWA Hiroyuki  丸澤 宏之

ORCIDConnect your ORCID iD *help
… Alternative Names

YOSHIDA Kenichi  吉田 健一

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Researcher Number 80324630
Other IDs
Affiliation (based on the past Project Information) *help 2018 – 2019: 京都大学, 医学研究科, 客員研究員
2017: 京都大学, 医学研究科, 准教授
2016: 京都大学, 医学(系)研究科(研究院), 准教授
2016: 京都大学, 医学(系)研究科, 講師
2016: 京都大学, 医学研究科, 講師 … More
2016: 京都大学, 大学院医学研究科, 准教授
2012 – 2015: 京都大学, 医学(系)研究科(研究院), 講師
2014: 京都大学, 医学研究科, 講師
2009 – 2012: Kyoto University, 医学研究科, 講師
2007 – 2008: Kyoto University, Graduate School of Medicine, Department of Gastroenterology and Hepatology, Assistant professor
2004 – 2006: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology
Except Principal Investigator
Gastroenterology / Digestive surgery / Cardiovascular medicine / Tumor biology / Biological Sciences / Biological Sciences
Keywords
Principal Investigator
肝癌 / 遺伝子変異 / AID / APOBEC3G / 肝細胞 / HBV / ウィルス / ゲノム / 癌 / 遺伝子異常 … More / 肝硬変 / HepG2 cell / hepatitis B virus / 抗ウィルス分子 / 免疫応答 / HepG2 / 感染モデル / B型肝炎 / 遺伝子編集酵素 / HBe抗原 / APOBEC / インターフェロン / B型肝炎ウィルス / 肝前駆細胞 / 幹細胞 / 前駆細胞 / p53 / 炎症 / APOBEC2 / リアルタイムPCR法 / 細胞周期 / siRNA / Survivin / HBXIP / アポトーシス … More
Except Principal Investigator
AID / 遺伝子変異 / H.pylori / 発がん / 炎症 / 癌幹細胞 / 遺伝子不安定性 / 胃癌 / p53 / NFκB / HCV / 炎症発癌 / 抗体作成 / 抗体治療 / 食道癌 / FGFRL1 / 癌 / 骨髄 / 慢性炎症 / コレステロール / HDL-C / ナノ粒子 / 線維化 / 動脈硬化 / マイクロRNA / 大腸 / 大腸癌 / H.Pylori / エピゲノム異常 / ゲノム異常 / エピゲノム / 組織幹細胞 / ゲノム / ヘリコバクター属細菌 / ヘリコバクター感染 / 感染 / インターフェロンガンマ / CXCL13 / 胃MALTリンパ腫 / ヘリコバクタースイス / 胃がん / ヘリコバクターピロリ / APOBEC2 / Colitic cancer / メチル化 / 消化器発癌 / 上部消化管学 / 4型分泌装置 / CagA / 胆管癌 / 肝臓癌 / 遺伝子編集酵素 / H. pylori Less
  • Research Projects

    (14 results)
  • Research Products

    (154 results)
  • Co-Researchers

    (23 People)
  •  Role of regeneration nodule in cirrhotic liver on tumorigenesisPrincipal Investigator

    • Principal Investigator
      Marusawa Hiroyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  The mutational background in colorectal carcinogenesis

    • Principal Investigator
      OGAWA SEiSHi
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kyoto University
  •  Integrated analysis of genetic and epigenetic alterations in hepatocellular carcinoma.Principal Investigator

    • Principal Investigator
      Marusawa Hiroyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Elucidation of the functions of microRNA-33 in homeostasis in vivo

    • Principal Investigator
      Ono Koh
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kyoto University
  •  Research on the treatment of esophageal cancer with anti-human fibroblast growth factor receptor like-1

    • Principal Investigator
      SHIMADA Yutaka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University
  •  Global anallysis of genetic and epigenetic alterations during inflammation-associated gastrointestinal cancer development, and elucidation of its mechanism

    • Principal Investigator
      CHIBA Tsutomu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Role of mutated hepatic progenitor cells on hepatocarcinogenesisPrincipal Investigator

    • Principal Investigator
      MARUSAWA HIROYUKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Genomic instability and mechanisms of carcinogenesis due to infection and inflammation

    • Principal Investigator
      AZUMA Takeshi
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Mechanism for genomic instability during inflammation-associated carcinogenesis

    • Principal Investigator
      CHIBA Tsutomu
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Role of activation-induced cytidine deaminase (AID) in the mutation induction during H.pylori-induced gastric carcinogenesis.

    • Principal Investigator
      CHIBA Tsutomu
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Mechanisms of genetic alterations during the process of liver cancer development.Principal Investigator

    • Principal Investigator
      MARUSAWA Hiroyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  消化器癌の発症・進展過程における新しい遺伝子変異導入機構の解明

    • Principal Investigator
      CHIBA Tsutomu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Identification of novel anti-hepatitis B virus defense mechanismsPrincipal Investigator

    • Principal Investigator
      MARUSAWA Hiroyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  新規アポトーシス制御分子HBXIPの肝発癌過程に果たす役割に関する研究Principal Investigator

    • Principal Investigator
      丸澤 宏之
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] In Cancer and Inflammation Mechanisms2014

    • Author(s)
      Marusawa H, Chiba T
    • Total Pages
      12
    • Publisher
      Wiley
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Book] Molecular Biology of B Cells (2nd edition)2014

    • Author(s)
      Takai A, Marusawa H, Chiba T
    • Total Pages
      9
    • Publisher
      Academic Press/Elsevier
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Book] Infection Biology Handbook Series. Bacterial Virulence. Basic principles, models and global approaches(Sansonetti P, ed)2010

    • Author(s)
      Chiba T, Marusawa H, Seno H, Watanabe N
    • Total Pages
      320
    • Publisher
      Willey-Blackwell
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Book] H. pylori infection-The route from inflammation to cancer. In Sansonetti P, ed, Infection Biology Handbook Series. Bacterial Virulence. Basic principles, models and global approaches.2010

    • Author(s)
      Chiba T, Marusawa H, Seno H, Watanabe N
    • Publisher
      Willey-Blackwell
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis2019

    • Author(s)
      Kim Soo Ki、Takeda Haruhiko、Takai Atsushi、Matsumoto Tomonori、Kakiuchi Nobuyuki、Yokoyama Akira、Yoshida Kenichi、Kaido Toshimi、Uemoto Shinji、Minamiguchi Sachiko、Haga Hironori、Shiraishi Yuichi、Miyano Satoru、Seno Hiroshi、Ogawa Seishi、Marusawa Hiroyuki
    • Journal Title

      Journal of Gastroenterology

      Volume: 印刷中 Issue: 7 Pages: 628-640

    • DOI

      10.1007/s00535-019-01555-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09357, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17H04158
  • [Journal Article] Proliferating EpCAM-Positive Ductal Cells in the Inflamed Liver Give Rise to Hepatocellular Carcinoma2017

    • Author(s)
      Matsumoto Tomonori、Takai Atsushi、Eso Yuji、Kinoshita Kazuo、Manabe Toshiaki、Seno Hiroshi、Chiba Tsutomu、Marusawa Hiroyuki
    • Journal Title

      Cancer Research

      Volume: 77 Issue: 22 Pages: 6131-6143

    • DOI

      10.1158/0008-5472.can-17-1800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09357, KAKENHI-PROJECT-17K15938, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-17H04158, KAKENHI-PROJECT-16K15427
  • [Journal Article] MSH2 dysregulation is triggered by proinflammatory cytokine stimulation and is associated with liver cancer development.2016

    • Author(s)
      Eso Y, Takai A, Matsumoto T, Inuzuka T, Horie T, Ono K, Uemoto S, Lee K, Edelmann W, Chiba T, Marusawa H
    • Journal Title

      Cancer Research

      Volume: 76 Pages: 4383-4393

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Journal Article] TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma.2016

    • Author(s)
      Ki Kim S, Ueda Y, Hatano E, Kakiuchi N, Takeda H, Goto T, Shimizu T, Yoshida K, Ikura Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Uemoto S, Chiba T, Ogawa S, Marusawa H.
    • Journal Title

      Int J Cancer.

      Volume: 139 Issue: 11 Pages: 2512-2518

    • DOI

      10.1002/ijc.30379

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26293172, KAKENHI-PROJECT-26461000
  • [Journal Article] MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.2016

    • Author(s)
      Eso Y, Takai A, Matsumoto T, Inuzuka T, Horie T, Ono K, Uemoto S, Lee K, Edelmann W, Chiba T, Marusawa H.
    • Journal Title

      Cancer Research

      Volume: 76 Issue: 15 Pages: 4383-93

    • DOI

      10.1158/0008-5472.can-15-2926

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16J11897, KAKENHI-PROJECT-26293186, KAKENHI-PROJECT-26461144
  • [Journal Article] Exploring the Mechanisms of Gastrointestinal Cancer Development Using Deep Sequencing Analysis2015

    • Author(s)
      Matsumoto T, Shimizu T, Takai A, Marusawa H
    • Journal Title

      Cancers (Basel)

      Volume: 7 Issue: 2 Pages: 1037-1051

    • DOI

      10.3390/cancers7020823

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J02212, KAKENHI-PROJECT-26293172
  • [Journal Article] Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.2015

    • Author(s)
      Sawai Y, Kodama Y, Shimizu T, Ota Y, Maruno T, Eso Y, Kurita A, Shiokawa M, Tsuji Y, Uza N, Matsumoto Y, Masui T, Uemoto S, Marusawa H, Chiba T.
    • Journal Title

      Cancer Res.

      Volume: 15 Issue: 16 Pages: 32923301-32923301

    • DOI

      10.1158/0008-5472.can-14-3028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293282, KAKENHI-PROJECT-26293172
  • [Journal Article] Interferon-γ-producing B cells induce the formation of gastric lymphoid follicles after Helicobacter suis infection.2015

    • Author(s)
      Yang L, Yamamoto K, Nishiumi S, Nakamura M, Matsui H, Takahashi S, Dohi T, Okada T, Kakimoto K, Hoshi N, Yoshida M, Azuma T.
    • Journal Title

      Mucosal Immunol

      Volume: 8 Issue: 2 Pages: 279-295

    • DOI

      10.1038/mi.2014.66

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-25305027, KAKENHI-PROJECT-15K19092
  • [Journal Article] Hepatic inflammation facilitates transcription-associated mutagenesis via AID activity and enhances liver tumorigenesis2015

    • Author(s)
      Matsumoto T, Shimizu T, Nishijima N, Ikeda A, Eso Y, Matsumoto Y, Chiba T, Marusawa H
    • Journal Title

      Carcinogenesis

      Volume: 36 Issue: 8 Pages: 904-913

    • DOI

      10.1093/carcin/bgv065

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J02212, KAKENHI-PROJECT-26293172
  • [Journal Article] Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes.2014

    • Author(s)
      Iwamoto A, Tanahashi T, Okada R, Yoshida Y, Kikuchi K, Murakami Y, Yang L, Yamamoto K, Nishiumi S, Yoshida M, Azuma T.
    • Journal Title

      Gut Pathog

      Volume: - Issue: 1 Pages: 6-6

    • DOI

      10.1186/1757-4749-6-27

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-26460212
  • [Journal Article] Reactivation from occult HBV carrier status is characterized by low genetic heterogeneity with the wild-type or G1896A variant prevalence2014

    • Author(s)
      Inuzuka T, Ueda Y, Morimura H, Fujii Y, Umeda M, Kou T, Osaki Y, Uemoto S, Chiba T, Marusawa H.
    • Journal Title

      Journal of Hepatology

      Volume: 61 Issue: 3 Pages: 492-501

    • DOI

      10.1016/j.jhep.2014.04.033

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J02056, KAKENHI-PROJECT-23590972, KAKENHI-PROJECT-24229005
  • [Journal Article] Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma.2014

    • Author(s)
      Ikeda A, Shimizu T, Matsumoto Y, Fujii Y, Eso Y, Inuzuka T, Mizuguchi A, Shimizu K, Hatano E, Uemoto S, Chiba T, Marusawa H
    • Journal Title

      Gastroenterology

      Volume: 146 Issue: 1 Pages: 222-232

    • DOI

      10.1053/j.gastro.2013.09.025

    • NAID

      120005372982

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24590915, KAKENHI-PROJECT-26293172
  • [Journal Article] Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection.2014

    • Author(s)
      Yamamoto K, Nishiumi S, Yang L, Kimatcheva E, Pandina T, Takahashi S, Matsui H, Nakamura M, Zauderer M, Yoshida M, Azuma T.
    • Journal Title

      Mucosal Immunol

      Volume: 7 Pages: 1244-1254

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22114006
  • [Journal Article] Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection.2014

    • Author(s)
      Yamamoto K, Nishiumi S, Yang L, Klimatcheva E, Pandina T, Takahashi S, Matsui H, Nakamura M, Zauderer M, Yoshida M, Azuma T.
    • Journal Title

      Mucosal Immunol.

      Volume: - Issue: 5 Pages: 1244-1254

    • DOI

      10.1038/mi.2014.14

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-25305027
  • [Journal Article] Modelling mutational landscapes of human cancers in vitro.2014

    • Author(s)
      Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallee MP, McKay J, Nedelko T, Muehlbauer KR, Marusawa H, Alexander J, Hazelwood L, Byrnes G, Hollstein M, Zavadil J
    • Journal Title

      Sci Rep

      Volume: 4 Issue: 1 Pages: 4482-4482

    • DOI

      10.1038/srep04482

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Journal Article] Enhanced expression of activation-induced cytidine deaminase in human gastric mucosa infected by Helicobacter pylori and its decrease following eradication.2014

    • Author(s)
      Nagata N, Akiyama J, Marusawa H, Shimbo T, Liu Y, Igari T, Nakashima R, Watanabe H, Uemura N, Chiba T.
    • Journal Title

      J Gastroenterol.

      Volume: 49(3) Issue: 3 Pages: 427-35

    • DOI

      10.1007/s00535-013-0808-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-24229005
  • [Journal Article] A model of liver carcinogenesis originating from hepatic progenitor cells with accumulation of genetic alterations.2014

    • Author(s)
      Soo Ki Kim, Akihiro Nasu, Junji Komori, Takahiro Shimizu, Yuko Matsumoto, Yasuko Minaki, Kenji Kohno, Kazuharu Shimizu, Shinji Uemoto, Tsutomu Chiba, Hiroyuki Marusawa.
    • Journal Title

      International Journal of Cancer

      Volume: 134 Issue: 5 Pages: 1067-76

    • DOI

      10.1002/ijc.28445

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J04612, KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24590915, KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-26293172, KAKENHI-PROJECT-24228002
  • [Journal Article] Accumulation of somatic mutations in TP53 in gastric epithelium with Helicobacter pylori infection.2014

    • Author(s)
      Shimizu T, Marusawa H, Matsumoto Y, Inuzuka T, Ikeda A, Fujii Y, Minamiguchi S, Miyamoto S, Kou T, Sakai Y, Crabtree JE, Chiba T.
    • Journal Title

      Gastroenterology

      Volume: 147 Issue: 2 Pages: 407-417

    • DOI

      10.1053/j.gastro.2014.04.036

    • NAID

      120005466713

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-24229005, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-26293172
  • [Journal Article] Inflammation and gastrointestinal cancer: An overview.2014

    • Author(s)
      Marusawa H, Jenkins BJ
    • Journal Title

      Cancer Lett

      Volume: 345 Issue: 2 Pages: 153-156

    • DOI

      10.1016/j.canlet.2013.08.025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Journal Article] Expression analysis of fibroblast growth factor receptor-like 1 (FGFRL1) in esophageal squamous cell carcinoma2014

    • Author(s)
      Shimada Y, Okumura T, Nagata T, Hashimoto I, Sawada S, Yoshida T, Fukuoka J, Shimizu K, Tsukada K
    • Journal Title

      Esopagus

      Volume: 11 Issue: 1 Pages: 48-53

    • DOI

      10.1007/s10388-013-0394-4

    • NAID

      40020229726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293302
  • [Journal Article] The RNA-editing enzyme APOBEC1 requires heterogeneous nuclear ribonucleoprotein Q isoform 6 for efficient interaction with interleukin-8 mRNA.2014

    • Author(s)
      Shimizu Y, Nishitsuji H, Marusawa H, Ujino S, Takaku H, Shimotohno K.
    • Journal Title

      J Biol Chem.

      Volume: 289 Issue: 38 Pages: 26226-26238

    • DOI

      10.1074/jbc.m114.563221

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24590557
  • [Journal Article] Novel mouse models of hepatocarcinogenesis with stepwise accumulation of genetic alterations.2013

    • Author(s)
      Soo Ki Kim, Hiroyuki Marusawa, Yuji Eso, Tsutomu Chiba, Masatoshi Kudo.
    • Journal Title

      Digestive Diseases

      Volume: 31 Issue: 5-6 Pages: 454-8

    • DOI

      10.1159/000355244

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J04612, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
  • [Journal Article] Chromosome painting in silico in a bacterial species reveals fine population structure2013

    • Author(s)
      Koji Yahara, Ynshikazu Furuta, Kenshiro Oshima, Masaru Yoshida, Takeshi Azuma, Masahira Hattori, Ikuo Uchiyama, Ichizo Kobayashi
    • Journal Title

      Molecular Biology and Evolution

      Volume: 30(6) Issue: 6 Pages: 1454-64

    • DOI

      10.1093/molbev/mst055

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J00830, KAKENHI-PROJECT-21370001, KAKENHI-PLANNED-22114006, KAKENHI-PUBLICLY-24113506, KAKENHI-PUBLICLY-24119503, KAKENHI-PROJECT-24790412, KAKENHI-PROJECT-25291080
  • [Journal Article] Targeting activation-inducedcytidine deaminase prevents coloncancer development despite persistentcolonic inflammation2012

    • Author(s)
      Takai A, Marusawa H, Minaki Y, WatanabeT, Nakase H, Kinoshita K, Tsujimoto G,Chiba T.
    • Journal Title

      Oncogene

      Volume: 31 Issue: 13 Pages: 1733-1742

    • DOI

      10.1038/onc.2011.352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23390097, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
  • [Journal Article] Excessive activity of apolipoproteinB mRNA editing enzyme catalyticpolypeptide 2 (APOBEC2) contiributes toliver and lung tumorigenesis.2012

    • Author(s)
      Okuyama S, Marusawa H, Matsumoto T, UedaY, Matsumoto Y, Endo Y, Takai A, ChibaT.
    • Journal Title

      Int Jcancer

      Volume: 130 Issue: 6 Pages: 1294-1301

    • DOI

      10.1002/ijc.26114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22890089, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
  • [Journal Article] Molecular mechanism of colitis-associated colorectal carcinogenesis2012

    • Author(s)
      Marusawa H
    • Journal Title

      Inflammation and Regeneration

      Volume: 32 Issue: 2 Pages: 067-071

    • DOI

      10.2492/inflammregen.32.067

    • NAID

      130004482296

    • ISSN
      1880-8190, 1880-9693
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Journal Article] Inflammation-associated cancerdevelopment in digestive organs:Mechanisms and roles for genetic andepigenetic modulation-.2012

    • Author(s)
      Chiba T, Marusawa H, Ushijima T
    • Journal Title

      Gastroenterology

      Volume: 143 Issue: 3 Pages: 550-563

    • DOI

      10.1053/j.gastro.2012.07.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-24229005, KAKENHI-PLANNED-22114006
  • [Journal Article] Molecular mechanism ofcolitis-associated colorectalcarcinogenesis2012

    • Author(s)
      Marusawa H, Endo Y, Takai A, Chiba T
    • Journal Title

      Inflamm Regeneration

      Volume: 32 Pages: 67-71

    • URL

      http://dx.doi.org/10.2492/inflammregen.32.067

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Genetic heterogeneity of hepatitis C virus in association with antiviral therapy determined by ultra-deep sequencing2011

    • Author(s)
      Nasu A, Marusawa H, Ueda Y, Nishijima N, Takahashi K, Osaki Y, Yamashita Y, Inokuma T, Tamada T, Fujiwara T, Sato F, Shimizu K, Chiba T
    • Journal Title

      PLoS One

      Volume: 6 Issue: 9 Pages: e24907-e24907

    • DOI

      10.1371/journal.pone.0024907

    • NAID

      120003437134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590972, KAKENHI-PROJECT-23659610
  • [Journal Article] Role of activation-induced cytidine deaminase in inflammation-associated cancer development2011

    • Author(s)
      Hiroyuki Marusawa, Atsushi Takai, Tsutomu Chiba
    • Journal Title

      Advances in Immunology

      Volume: 111 Pages: 109-141

    • DOI

      10.1016/b978-0-12-385991-4.00003-9

    • ISBN
      9780123859914
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J02494, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23390196
  • [Journal Article] Excessive activity of apolipoprotein B mRNA editing enzyme catalytic popypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.2011

    • Author(s)
      Okuyama S, Marusawa H, Matsumoto T, Ueda Y, Matsumoto Y, Endo Y, Takai A, Chiba T
    • Journal Title

      Int J Cancer

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Excessive activity of APOBEC2 contributes to liver and lung tumorigenesis.2011

    • Author(s)
      Okuyama S, Marusawa H, Matsumoto T, Ueda Y, Matsumoto Y, Endo Y, Takai A, Chiba T.
    • Journal Title

      Int J Cancer in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] A marker for dormant cancer stem cells in human hepatocellular carcinoma2011

    • Author(s)
      Marusawa H, Chiba T
    • Journal Title

      Gastroenterology

      Volume: 140 Issue: 4 Pages: 1353-1355

    • DOI

      10.1053/j.gastro.2011.02.039

    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Bileacid-induced expression ofactivation-induced cytidine deaminaseduring the development of Barrett'soesophageal adenocarcinoma.2011

    • Author(s)
      Morita S, Matsumoto Y, Okuyama S, Ono K,Kitamura Y, Tomori A, Oyama T, Amano Y,Kinoshita Y, Chiba T, Marusawa H.
    • Journal Title

      Carcinogenesis

      Volume: 32 Issue: 11 Pages: 1706-1712

    • DOI

      10.1093/carcin/bgr194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22890089
  • [Journal Article] Excessive activity of APOBEC2 contributes to liver and lung tumorigenesis.2011

    • Author(s)
      Okuyama S, Marusawa H, Matsumoto T, Ueda Y, Matsumoto Y, Endo Y, Takai A, Chiba T.
    • Journal Title

      Int J Cancer

      Volume: (Epub ahead of print (印刷中))

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] A marker for dormant cancer stem cells in human hepatocellular carcinoma.2011

    • Author(s)
      Marusawa H, Chiba T
    • Journal Title

      Gastroenterology

      Volume: (印刷中)

    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Acquisition of genetic aberrations by activation-induced cytidine deaminase (AID) during inflammation-associated carcinogenesis2011

    • Author(s)
      Atsushi Takai, Hiroyuki Marusawa, Tsutomu Chiba
    • Journal Title

      Cancers

      Volume: 7 Issue: 2 Pages: 2750-2761

    • DOI

      10.3390/cancers3022750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J02494, KAKENHI-PROJECT-21229009
  • [Journal Article] Involvementof activation-induced cytidinedeaminase in the development ofcolitis-associated colorectal cancers2011

    • Author(s)
      Endo Y, Marusawa H, Chiba T
    • Journal Title

      J Gastroenterol

      Volume: 46 (Suppl 1) Issue: S1 Pages: 6-10

    • DOI

      10.1007/s00535-010-0326-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Role ofactivation-induced cytidine deaminasein inflammation-associated cancerdevelopment2011

    • Author(s)
      Marusawa H, Takai A, Chiba T
    • Journal Title

      Adv Immunol

      Volume: 111 Pages: 109-141

    • URL

      http://dx.doi.org/10.1016/B978-0-12-385991-4.00003-9

    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis.2010

    • Author(s)
      Marusawa H, Chiba T.
    • Journal Title

      Curr Opin Immunol 22

      Pages: 442-7

    • NAID

      120002511343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] H.pylori infection -The route frominflammation to cancer. In Sansonetti P,ed, Infection Biology Handbook Series.Bacterial Virulence. Basic principles,models and global approaches2010

    • Author(s)
      Chiba T, Marusawa H, Seno H, Watanabe N
    • Journal Title

      Willey-Blackwell

      Pages: 31-41

    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Up-regulation of activation-inducedcytidine deaminase causes geneticaberrations at the CDKN2b-CDKN2a ingastric cancer2010

    • Author(s)
      Matsumoto Y, Marusawa H, Kinoshita K,Niwa Y, Sakai Y, Chiba T
    • Journal Title

      Gastroenterology

      Volume: 139 Issue: 6 Pages: 1984-1994

    • DOI

      10.1053/j.gastro.2010.07.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Upregulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer.2010

    • Author(s)
      Matsumoto Y, Marusawa H, Kinoshita K, Niwa Y, Sakai Y, Chiba T.
    • Journal Title

      Gastroenterology 139

      Pages: 1984-94

    • NAID

      120002696051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Helicobacterpylori-induced activation-inducedcytidine deaminase expression andcarcinogenesis2010

    • Author(s)
      Marusawa H, Chiba T
    • Journal Title

      Curr Opi Immunol

      Volume: 22 Issue: 4 Pages: 442-447

    • DOI

      10.1016/j.coi.2010.06.001

    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis.2010

    • Author(s)
      Marusawa H, Chiba T.
    • Journal Title

      Curr Opin Immunol

      Volume: 22 Pages: 442-447

    • NAID

      120002511343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Upregulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer.2010

    • Author(s)
      Matsumoto Y, Marusawa H, Kinoshita K, Niwa Y, Sakai Y, Chiba T.
    • Journal Title

      Gastroenterology

      Volume: 139 Pages: 1984-1994

    • NAID

      120002696051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer.2010

    • Author(s)
      Matsumoto Y, Marusawa H, Kinoshita K, Niwa Y, Sakai Y, Chiba T
    • Journal Title

      Gastroenterology

      Volume: 139 Pages: 1984-1994

    • NAID

      120002696051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis.2010

    • Author(s)
      Marusawa H, Chiba T
    • Journal Title

      Curr Opi Immunol

      Volume: 22 Pages: 1-6

    • NAID

      120002511343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers.2009

    • Author(s)
      Ikeuchi K, Marusawa H, Fujiwara M, Matsumoto Y, Endo Y, Watanabe T, Iwai A, Sakai Y, Takahashi R, Chiba T.
    • Journal Title

      Int J Cancer 125

      Pages: 2029-2035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009

    • Author(s)
      Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki IM, Honjo T, Chiba T, Kinoshita K.
    • Journal Title

      Oncogene 28

      Pages: 469-478

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009

    • Author(s)
      Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki I, Honjo T, Chiba T, Kinoshita K
    • Journal Title

      Oncogene 28

      Pages: 469-478

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction.2009

    • Author(s)
      Chiba T, Marusawa H
    • Journal Title

      J Mol Med 87

      Pages: 1023-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] A novel mechanism for inflammation-associated carcinogenesis ; an important role of activation-induced cytidine deaminase (AID) in mutation induction.2009

    • Author(s)
      Chiba T, Marusawa H.
    • Journal Title

      J Mol Med 87

      Pages: 1023-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Attenuation of proteolysis-mediatedcyclin E regulation by alternativelyspliced Parkin in human colorectalcancers2009

    • Author(s)
      Ikeuchi K, Marusawa H, Fujiwara M,Matsumoto Y, Endo Y, Watanabe T, Iwai A,Sakai Y, Takahashi R, Chiba T
    • Journal Title

      Int J Cancer

      Volume: 125 Issue: 9 Pages: 2029-2035

    • DOI

      10.1002/ijc.24565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] A novel mechanism for inflammation-associated carcinogenesis ; an important role of activation-induced cytidine deaminase (AID) in mutation induction.2009

    • Author(s)
      Chiba T Marusawa H.
    • Journal Title

      J Mol Med 87

      Pages: 1023-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] A novelmouse model of hepatocarcinogenesistriggered by AID causing deleteriousp53 mutations2009

    • Author(s)
      Takai A, Toyoshima T, Uemura M, KitawakiY, Marusawa H, Hiai H, Yamada S, OkazakiI, Honjo T, Chiba T, Kinoshita K
    • Journal Title

      Oncogene

      Volume: 28 Issue: 4 Pages: 469-478

    • DOI

      10.1038/onc.2008.415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Journal Article] A novel mechanism for inflammation-associated carcinogenesis ; an important role of activation-induced cytidine deaminase (AID) in mutation induction.2009

    • Author(s)
      Chiba T, Marusawa H
    • Journal Title

      J Mol Med 87

      Pages: 1023-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] Detection of activation-induced cytidine deaminase in gastric epithelial cells infected with cag pathogenicity island-positive Helicobacter pylori.2008

    • Author(s)
      Matsumoto Y, Marusawa H, Kinoshita K, Honjo T, Chiba T
    • Journal Title

      Nature Protocols (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Activation-induced cytidine deaminase links between inflammation to colitis-associated colorectal cancers.2008

    • Author(s)
      Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
    • Journal Title

      Gastroenterology 135

      Pages: 889-898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008

    • Author(s)
      Komori J, Marusawa H, Chiba T, et al.
    • Journal Title

      Hepatology 47

      Pages: 888-896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.2008

    • Author(s)
      Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T.
    • Journal Title

      Gastroenterology 135

      Pages: 889-898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Mechanism for gastric cancer development by Helicobacter pylori ifection.2008

    • Author(s)
      Chiba T, Marusawa H, Seno H, Watanabe N
    • Journal Title

      J Gastroenterol Hepatol 23

      Pages: 1175-1181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] Aberrant AID expression and human cancer development.2008

    • Author(s)
      Marusawa H
    • Journal Title

      Int J Biochem Cell Biol 40

      Pages: 1399-1402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.2008

    • Author(s)
      Morisawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T, Chiba T.
    • Journal Title

      Int J Cancer 123

      Pages: 2735-2740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Parkin as a tumor suppressor gene for hepatocellular carcinoma.2008

    • Author(s)
      Fujiwara M, Marusawa H, Wang HQ, Iwai A, Ikeuchi K, Imai Y, Kataoka A, Nukina N, Takahashi R, Chiba T.
    • Journal Title

      Oncogene 27

      Pages: 6002-6011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Organ-specific profiles of genetic changes in cancers caused by AID expression.2008

    • Author(s)
      Morisawa T, Marusawa H, et al.
    • Journal Title

      Int J Cancer. 123

      Pages: 2735-2740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Aberrant AID expression and human cancer development.2008

    • Author(s)
      Marusawa H
    • Journal Title

      Int J Biochem Cell Biol. 40

      Pages: 1399-1404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008

    • Author(s)
      Komori J, Marusawa H, Chiba T, et. al.
    • Journal Title

      Hepatology 47

      Pages: 888-896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008

    • Author(s)
      Komori J, Marusawa H, Machimoto T, Endo Y, Kinoshita K, Kou T, Haga H, Ikai I, Uemoto S, Chiba T
    • Journal Title

      Hepatology 47

      Pages: 888-896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] Activation-induced cytidine deaminase links between inflammation to colitis-associated colorectal cancers.2008

    • Author(s)
      Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
    • Journal Title

      Gastroenterology 135

      Pages: 889-898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2008

    • Author(s)
      Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki I, Honjo T, Chiba T, Kinoshita K
    • Journal Title

      Oncogene 28

      Pages: 469-478

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008

    • Author(s)
      Komori J, Marusawa H, Machimoto T, Endo Y, Kinoshita K, Kou T, Haga H, Ikai I, Uemoto S, Chiba T.
    • Journal Title

      Hepatology 47

      Pages: 888-896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Journal Article] Mechanism for gastric cancer development by Helicobacter pylori infection.2008

    • Author(s)
      Chiba T, Marusawa H, Seno H, Watanabe N
    • Journal Title

      J Gastroenterol Hepatol 23

      Pages: 1175-1181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.2008

    • Author(s)
      Morisawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T, Chiba T
    • Journal Title

      Int J Cancer 123

      Pages: 2735-2740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cvtidine deaminase expression.2008

    • Author(s)
      Monsawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T. Chiba T
    • Journal Title

      Int J Cancer 123

      Pages: 1175-1181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.2007

    • Author(s)
      Matsumoto Y, Marusawa H, Chiba T, et. al.
    • Journal Title

      Nat Med 13

      Pages: 470-476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.2007

    • Author(s)
      Kou T, Marusawa H, Kinoshita K, Endo Y, Okazaki IM, Ueda Y, Kodama Y, Haga H, Ikai I, Chiba T
    • Journal Title

      Int J Cancer 120

      Pages: 469-476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes during carcinogenesis.2007

    • Author(s)
      Kou T, Marusawa H, Kinoshita K, Endo Y, Okazaki IM, Ueda Y, Kodama Y, Haga H, Ikai I, Chiba T.
    • Journal Title

      Int J Cancer. 120

      Pages: 469-476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590731
  • [Journal Article] Expression of human activation-induced cytidine deaminase in human hepatocytes via NF-kB signaling.2007

    • Author(s)
      Endo Y, Marusawa H, Chiba T, et. al.
    • Journal Title

      Oncogene 26

      Pages: 5587-5595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Journal Article] Growth and differentiation of colony-forming human hepatocytes in vitro.2006

    • Author(s)
      Yamasaki C, Marusawa H, et al.
    • Journal Title

      Journal Hepatology 44

      Pages: 749-757

    • NAID

      120000878102

    • Data Source
      KAKENHI-PROJECT-16790378
  • [Journal Article] Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.2006

    • Author(s)
      Tanaka Y, Marusawa H, et al.
    • Journal Title

      Biochem Biophys Res Commun. 341

      Pages: 314-319

    • Data Source
      KAKENHI-PROJECT-18590731
  • [Journal Article] Anti-viral protein APOBEC3G is induced by interferon-alfa stimulation in human hepatocytes.2006

    • Author(s)
      Tanaka Y, Marusawa H, et. al.
    • Journal Title

      Biochem Biophys Res Commun. 341

      Pages: 314-319

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590731
  • [Journal Article] Anti-viral protein APOBEC3G is induced by interferon-alfa stimulation in human hepatocytes2006

    • Author(s)
      Tanaka, Y., Marusawa, H., Seno, H., Matusmoto, Y., Ueda, Y., Kodama, Y., Endo, Y., Yamauchi, J., Matsumoto, T., Takaori-Kondo, A., Ikai, I., Chiba, T
    • Journal Title

      BBRC 341

      Pages: 314-319

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590731
  • [Journal Article] Hepatitis B virus infection in lymphatic tissues in inactive hepatitis B carriers.2005

    • Author(s)
      Umeda M, Marusawa H, et al.
    • Journal Title

      Journal Hepatology 42

      Pages: 806-812

    • Data Source
      KAKENHI-PROJECT-16790378
  • [Presentation] 肝がんのゲノム情報に基づく成因別治療選択の可能性2018

    • Author(s)
      金 秀基,竹田治彦,丸澤宏之
    • Organizer
      第54回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17H04158
  • [Presentation] Oncogenic Potential of Cirrhotic Liver Tissues Determined by Deep-Sequencing Analyses.2018

    • Author(s)
      Soo Ki Kim , Haruhiko Takeda , Hiroyuki Marusawa.
    • Organizer
      APASL 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04158
  • [Presentation] 起源細胞の違いに基づいた肝癌の腫瘍特性の同定2017

    • Author(s)
      松本知訓、高井淳、恵荘裕嗣、木下和生、千葉勉、妹尾浩、丸澤宏之
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04158
  • [Presentation] 肝炎症発癌におけるDNAミスマッチ修復遺伝子MSH2の発現低下と変異パターンの関連性2016

    • Author(s)
      恵荘裕嗣、高井淳、千葉勉、妹尾浩、丸澤宏之
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] The carcinogenic sequence in colitis-associated cancer/潰瘍性大腸炎関連大腸癌の発癌機序2016

    • Author(s)
      Nobuyuki Kakiuchi, Kenichi Yoshida, Yusuke Shiozawa, Kenichi Chiba, Yuichi Shiraishi, Takaki Sakurai, Yoshiharu Sakai, Motoi Uchino, Seiichi Hirota, Hiroki Ikeuchi, Satoru Miyano, Hiroyuki Marusawa, Seishi Ogawa
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14607
  • [Presentation] Genomic approaches to uncover clonal structure and oncogenic potential of liver cirrhosis2016

    • Author(s)
      Kim SK, Ogawa S, Marusawa H
    • Organizer
      第58回日本消化器病学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] EpCAM陽性肝幹/前駆細胞は肝細胞癌の起源となる2016

    • Author(s)
      松本知訓、高井淳、恵荘裕嗣、千葉勉、妹尾浩、丸澤宏之
    • Organizer
      第75回日本癌学会学術総
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] 肝癌の発生母地としての肝硬変組織に潜在するゲノム異常2016

    • Author(s)
      金秀基、吉田健一、垣内伸之、上田佳秀、南口早智子、海道利実、白石友一、宮野悟、羽賀博典、上本伸二、妹尾浩、小川誠司、丸澤宏之
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] 食道扁平上皮癌の染色体コピー数異常における予後関連因子の検討2015

    • Author(s)
      後藤知之、島田裕、金秀基、清水孝洋、髙井淳、千葉勉、丸澤宏之
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      愛知県 名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] 膵癌進展におけるactivation-induced cytidine deaminase(AID)の役割2015

    • Author(s)
      大田悠司、澤井勇吾、児玉裕三、丸澤宏之、千葉勉
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      愛知県 名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] 脂肪肝疾患に由来するヒト肝がんのゲノム異常の特性2015

    • Author(s)
      金秀基、後藤知之、千葉勉、丸澤宏之
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      愛知県 名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] 消化器癌のゲノムワイドなコピー数異常と全ゲノムコピー数解析の実際2015

    • Author(s)
      丸澤宏之
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      愛知県 名古屋国際会議場
    • Year and Date
      2015-10-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] 慢性炎症は転写上昇を介してゲノム変異導入を亢進し肝発癌を促進する2014

    • Author(s)
      松本知訓、西島規浩、千葉勉、丸澤宏之
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 横浜市 神奈川県
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] Aberrant expression of activation-induced cytidine deaminase (AID) induces genetic alterations and contributes to hepatocarcinogenesis.2014

    • Author(s)
      Soo Ki Kim, Hiroyuki Marusawa, Tsutomu Chiba
    • Organizer
      文部科学省「個体レベルでのがん研究支援活動」ワークショップ・「個体レベルからみた炎症とがん -がん発生・進展における個体内相互作用-」
    • Place of Presentation
      琵琶湖ホテル
    • Year and Date
      2014-02-18
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] Mutation profiles of hepatocellular carcinoma developed in nonalcoholic fatty liver disease. 脂肪性肝疾患に発生する肝癌のゲノム異常解析2014

    • Author(s)
      金秀基、千葉勉、丸澤宏之
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 横浜市 神奈川県
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] Prognostic value of somatic mutations in esophageal squamous cell caricinoma2014

    • Author(s)
      後藤知之、嶋田 裕、清水孝洋、千葉 勉、丸澤宏之
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] Mutation profiles of hepatocellular carcinoma developed in nonalcoholic fatty liver disease2014

    • Author(s)
      金 秀基、千葉 勉、丸澤宏之
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] Inflammation contributes to liver tumorigenesis through an acceleration of transcription-coupled mutagenesis2014

    • Author(s)
      松本知訓、西島規浩、千葉 勉、丸澤宏之
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] AID/TAA 誘発肝発癌モデルマウスを用いた、肝発癌過程におけるゲノム・エピゲノム変化の解析2014

    • Author(s)
      松本知訓、丸澤宏之、池田敦之、西島規浩、金 秀基、千葉 勉
    • Organizer
      文部科学省「個体レベルでのがん研究支援活動」ワークショップ・「個体レベルからみた炎症とがん -がん発生・進展における個体内相互作用-」
    • Place of Presentation
      琵琶湖ホテル
    • Year and Date
      2014-02-18
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] NBNC肝癌におけるNASH肝癌の位置づけとゲノム異常の網羅的解析2014

    • Author(s)
      金秀基、波多野悦朗、丸澤宏之
    • Organizer
      第56回日本消化器病学会大会
    • Place of Presentation
      ポートピアホテル本館 兵庫県 神戸市
    • Year and Date
      2014-10-25
    • Data Source
      KAKENHI-PROJECT-26293172
  • [Presentation] Actibation-induced cytidine deaminaseは発癌性変異を誘導し膵発癌に寄与している2013

    • Author(s)
      澤井勇悟、児玉裕三、丸澤宏之、千葉 勉
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-04
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] ワークショップ16 : 消化器癌に対する幹細胞研究の現状と展望 (肝W16-9) 肝幹/前駆細胞を起源とする肝発癌モデルを用いたゲノム異常の網羅的解析2013

    • Author(s)
      金秀基, 丸澤宏之.千葉勉
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      品川プリンスホテル.東京
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] Induction of genetic aberration during gastric cancer debelopment by H.pylori infection2013

    • Author(s)
      Tsutomu Chiba, Yuko Matsumoto, Takahiro Shimizu, Hiroyuki Marusawa.
    • Organizer
      The4th JCA-AACR Special conference
    • Place of Presentation
      Tokyo Bay Maihama Hotel Club & Resorts
    • Year and Date
      2013-12-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] 炎症と遺伝性不安定性2013

    • Author(s)
      千葉 勉、丸澤宏之
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] 膵発癌におけるActivation-induced cytidine deaminaseの意義2013

    • Author(s)
      澤井勇悟、児玉裕三、丸澤宏之、千葉 勉
    • Organizer
      第44回日本膵臓学会大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2013-07-25
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] シンポジウム3 : ゲノム不安定性とがん (S3-3) 炎症と遺伝子不安定性2013

    • Author(s)
      千葉勉, 丸澤宏之
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜.神奈川
    • Year and Date
      2013-10-03
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] 慢性炎症によるゲノム異常生成と肝発癌2013

    • Author(s)
      丸澤宏之
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-04
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] Activation-induced cytidine deaminase(AID) contributes to pancreatic cancer intiation by induction of tumor related gene mutations2013

    • Author(s)
      Yugo Sawai, Yuzo Kodama, Yuji Ota, Masahiro Shiokawa, Akira Kurita, Norimitsu Uza, Hiroyuki Marusawa, Tsutomu Chiba
    • Organizer
      DDW2013
    • Place of Presentation
      Orando USA
    • Year and Date
      2013-05-20
    • Data Source
      KAKENHI-PROJECT-24229005
  • [Presentation] シンポジウム1 : 感染がん・炎症がんの分子基盤 (S1-1) 慢性炎症によるゲノム異常生成と肝発癌2013

    • Author(s)
      丸澤宏之
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜.神奈川
    • Year and Date
      2013-10-04
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] シンポジウム11 : 肝疾患に対する先端医療(肝S11-3) 次世代シーケンサーの肝疾患診療への応用~肝発癌のゲノム診断~2012

    • Author(s)
      池田敦之, 丸澤宏之, 千葉勉
    • Organizer
      第54回日本消化器病学会. 第16回日本肝臓学会大会
    • Place of Presentation
      ポートピアホテル.兵庫
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] Gastric cancer development by Helicobacter pylori (H.pylori)infection-important roles of activation-induced cytidine deaminase (AID) in induction of gene mutations and genomic instability during inflammation-associated carcinogenesis2012

    • Author(s)
      Tsutomu Chiba, Hiroyuki Marusawa
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎新聞文化ホール(長崎)(招待講演)
    • Year and Date
      2012-03-28
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] E-1032 : Liver cancer is originated from the hepatic progenitor cells through the accumulation of genetic alterations.(肝幹細胞/前駆細胞への遺伝子異常の蓄積が肝癌の発生に果たす役割)2012

    • Author(s)
      金秀基, 丸澤宏之, 那須章洋, 千葉勉
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市教育文化会館. 北海道
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] 炎症刺激により発現誘導される遺伝子編集酵素ファミリーによる多段階肝発癌モデルマウスの解析2011

    • Author(s)
      奥山俊介, 丸澤宏之, 千葉勉
    • Organizer
      第53回消化器病学会(第15回日本肝臓学会大会 パネルディスカッション4)
    • Place of Presentation
      福岡国際会議場.福岡
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] 肝癌の発生・進展を規定するゲノム異常の次世代シーケンサー解析2011

    • Author(s)
      池田敦之、丸澤宏之、千葉勉
    • Organizer
      JDDW2011第82回日本消化器内視鏡学会大会・パネルディスカッション
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2011-10-23
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 慢性炎症により誘導されるゲノム異常からの肝癌発生機構2011

    • Author(s)
      丸澤宏之
    • Organizer
      第70回日本癌学会学術総会・International sessions
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] H.pylori感染により惹起される胃粘膜における遺伝子異常の飛躍的解析およびその生成機構2011

    • Author(s)
      清水孝洋、丸澤宏之、千葉勉
    • Organizer
      第70回日本癌学会学術総会・oral sessions
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 肝癌の発生・進展を規定するゲノム異常の次世代シーケンサー解析2011

    • Author(s)
      池田敦之, 丸澤宏之, 千葉勉
    • Organizer
      第53回消化器病学会(第15回日本肝臓学会大会 パネルディスカッション21)
    • Place of Presentation
      福岡国際会議場.福岡
    • Year and Date
      2011-10-23
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] 肝癌の発生母地としての肝硬変に潜在する遺伝子異常の次世代ゲノム解析2011

    • Author(s)
      池田敦之、丸澤宏之、千葉勉
    • Organizer
      第70回日本癌学会学術総会・Poster sessions
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 肝幹細胞/前駆細胞への遺伝子異常の蓄積が肝癌の発生に果たす役割2011

    • Author(s)
      那須章洋、丸澤宏之、千葉勉
    • Organizer
      JDDW2011第53回日本消化器病学会大会・ワークショップ
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 慢性炎症により誘導されるゲノム異常からの肝癌発生機構2011

    • Author(s)
      丸澤宏之
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場.愛知
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] 慢性炎症により誘導されるゲノム異常からの肝癌発生機構2011

    • Author(s)
      丸澤宏之
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] H.pylori感染からの胃癌発生過程により惹起される遺伝子コピー異常の生成機構2011

    • Author(s)
      清水孝洋、丸澤宏之、千葉勉
    • Organizer
      JDDW2011第53回日本消化器病学会大会・シンポジウム
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 肝癌の発生母地としての肝硬変に潜在する遺伝子異常の次世代ゲノム解析2011

    • Author(s)
      池田敦之, 丸澤宏之, 千葉勉
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場.愛知
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-23390196
  • [Presentation] 慢性炎症により誘導されるゲノム異常からの肝癌発生機構2011

    • Author(s)
      丸澤宏之
    • Organizer
      第70回日本癌学会学術総会・International sessions
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] Genetic aberration in hepatic stem cells leads to hepatocarcinogenesis.2010

    • Author(s)
      Marusawa H, Chiba T.
    • Organizer
      The 1st JSGE International Conference "Stem Cells in Digestive Organs"
    • Place of Presentation
      Kamakura(Invited Lecture)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] The role of somaticmutations accumulated in hepaticstem/ progenitor cells in the deveropment of hepatocellular carcinoma2010

    • Author(s)
      Atsushi Takai, Hiroyuki Marusawa Tsutomu Chiba
    • Organizer
      The 1st JSGE International TopicConference
    • Place of Presentation
      鎌倉
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] AIDによる発癌関連遺伝子への変異生成と炎症発癌2010

    • Author(s)
      丸澤宏之
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Presentation] Gastric Cancer Development by Helicobacter pylori (H.pylori) Infection-Important Roles of Activation-Induced Cytidine Deaminase (AID) in Induction of Gene Mutations and Genomic Instability during Inflammation-Associated Carcinogenesis2010

    • Author(s)
      Tsutomu Chiba, Hiroyuki Marusawa, Yuko Matsumoto, Atsushi Takai
    • Organizer
      Kyoto University Global COE "Center for Frontier Medicine" International Symposium/Retreat 2010
    • Place of Presentation
      Awajishima
    • Year and Date
      2010-11-06
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 炎症からの発癌における新しい遺伝子変異導入機構2009

    • Author(s)
      千葉勉、丸澤宏之
    • Organizer
      第82回日本生化学会大会・シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] H. Pylori infection induces gene mutations in gastric epithelial cells via induction of AID.2009

    • Author(s)
      千葉勉、松本裕子、丸澤宏之
    • Organizer
      第82回日本細菌学会総会・シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] A novel mechanism for mutagenesis in Helicobacter pylori-associated carcinogenesis-roles of activation-induced cytidine deaminase(AID)as a genome mutator-.2009

    • Author(s)
      Tsutomu Chiba, Yuko Matsumoto, Hiroyuki Marusawa
    • Organizer
      15th International Workshop on Campylobacter, Helicobacter, and Related Organisms
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-02
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] 肝幹/前駆細胞への遺伝子異常蓄積からの肝発癌機序.2009

    • Author(s)
      高井淳、丸澤宏之、千葉勉
    • Organizer
      第51回日本消化器病学会大会・第13回日本肝臓学会大会JDDW2009国立京都国際会館ワークショップ
    • Place of Presentation
      京都
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Presentation] 消化器癌の発生過程において炎症が遺伝子異常の生成に果たす役割2009

    • Author(s)
      丸澤宏之
    • Organizer
      第51回日本消化器病学会大会・第13回日本肝臓学会大会JDDW2009国立京都国際会館シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Presentation] 炎症発癌におけるゲノム不安定性誘導機序の解析とその標的治療2009

    • Author(s)
      丸澤宏之、千葉勉
    • Organizer
      第37回日本臨床免疫学会総会東京ステーションコンファレンスシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Presentation] 炎症からの発癌における新しい遺伝子変異導入機構2009

    • Author(s)
      千葉勉、丸澤宏之
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] H. Pylori infection induces gene mutations in gastric epithelial cells via induction of AID2009

    • Author(s)
      千葉勉, 松本裕子, 丸澤宏之
    • Organizer
      第82回日本細菌学会総会・シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Presentation] H.pylori感染による胃癌発癌機構2009

    • Author(s)
      千葉 勉、丸澤宏之、渡部則彦
    • Organizer
      第106回日本内科学会講演会・シンポジウ
    • Place of Presentation
      東京
    • Year and Date
      2009-04-10
    • Data Source
      KAKENHI-PROJECT-21229009
  • [Presentation] 消化器癌の発生過程において炎症が遺伝子異常の生成に果たす役割2009

    • Author(s)
      丸澤宏之
    • Organizer
      第51回日本消化器病学会大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Presentation] 胃発癌過程における遺伝子異常発生時期から見たH. pylori除菌療法の考察2008

    • Author(s)
      丸澤宏之、松本裕子、森田周子
    • Organizer
      第50回日本消化器病学会大会・シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] Helicobacter pylori感染によるAID発現を介したヒトゲノム異常生成の分子機構2008

    • Author(s)
      丸澤宏之、松本裕子、千葉勉
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-10
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] Helicobacter pylori infection induces gene mutations in gastric epithelial cells via induction of activation-induced cytidine deaminase (AID)2008

    • Author(s)
      Yuko Matsumoto, Hiroyuki Marusawa, Yoko Endo, Tsutomu Chiba
    • Organizer
      8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections (session)
    • Place of Presentation
      Helsinki, Denmark
    • Year and Date
      2008-07-04
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Presentation] Helicobacter pylori infection induces gene mutations in gastric epithelial cells via induction of activation-induced cytidine deaminase(AID).2008

    • Author(s)
      Y Matsumoto, H Marusawa, Y Endo, T Chiba
    • Organizer
      8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections
    • Place of Presentation
      Helsinki (Denmark)
    • Year and Date
      2008-07-04
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] Helicobacter pylori感染によるAID発現を介したヒトゲノム異常生成の分子機構2008

    • Author(s)
      丸澤宏之, 松本裕子, 千葉勉
    • Organizer
      第94回日本消化器病学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-10
    • Data Source
      KAKENHI-PROJECT-19659181
  • [Presentation] 炎症性腸疾患からの大腸発癌過程におけるActivation-induced cytidine deaminase(AID)の役割2008

    • Author(s)
      遠藤容子、丸澤宏之、木下和生、高忠之、藤井茂彦、藤盛孝博、千葉勉
    • Organizer
      第67回日本癌学会学術総会・ワークショップ
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20012029
  • [Presentation] 慢性肝疾患からの肝癌発生の分子機序2008

    • Author(s)
      丸澤宏之
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-20590774
  • [Presentation] 肝幹/前駆細胞を起源とする肝発癌モデルを用いたゲノム異常の網羅的解析

    • Author(s)
      金秀基、丸澤宏之
    • Organizer
      第17回日本肝臓学会大会
    • Place of Presentation
      品川プリンスホテル(東京)
    • Data Source
      KAKENHI-PROJECT-23390196
  • 1.  CHIBA Tsutomu (30188487)
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    # of Collaborated Products: 69 results
  • 2.  WATANABE Tomohiro (40444468)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  KINOSHITA Yoshikazu (30243306)
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    # of Collaborated Products: 5 results
  • 4.  UEDA Yoshihide (90378662)
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    # of Collaborated Products: 3 results
  • 5.  AZUMA Takeshi (60221040)
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  • 6.  USHIJIMA Toshikazu (90232818)
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  • 7.  OGAWA SEiSHi (60292900)
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  • 8.  SAKAI Yoshiharu (60273455)
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  • 9.  Ono Koh (00359275)
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  • 10.  NAKAMURA Tomoyuki (20362527)
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  • 11.  SHIMADA Yutaka (30216072)
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    # of Collaborated Products: 1 results
  • 12.  ITOU Yuji (60223195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TUCHIYA Soken (80423002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OHTSUJI Eigo (20244600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TSUKADA Kazuhiro (90171967)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  MATSUMOTO Osamu (10231599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  堀江 貴裕 (20565577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  清水 一治 (50456836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  武井 義則 (30502455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MASUI Toshihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  高井 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 22.  上本 伸二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  下遠野 邦忠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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