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INOZUME Takashi  猪爪 隆史

ORCIDConnect your ORCID iD *help
… Alternative Names

猪爪 隆史  イノヅメ タカシ

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Researcher Number 80334853
Other IDs
Affiliation (Current) 2025: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 千葉大学, 大学院医学研究院, 教授
2020 – 2022: 千葉大学, 大学院医学研究院, 講師
2018 – 2019: 山梨大学, 大学院総合研究部, 講師
2017: 山梨大学, 医学部, 専任講師
2014 – 2017: 山梨大学, 総合研究部, 講師 … More
2011 – 2013: 山梨大学, 医学部附属病院, 助教
2003 – 2005: 山梨大学, 医学部附属病院, 助手
2002: 山梨大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related / Dermatology
Except Principal Investigator
Basic Section 53050:Dermatology-related / Dermatology / Basic Section 57060:Surgical dentistry-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56050:Otorhinolaryngology-related
Keywords
Principal Investigator
メラノーマ / 抗PD-1抗体 / CD155 / TIGIT / 免疫チェックポイント / バイオマーカー / 腫瘍特異的T細胞 / TIL / PD-1 / T cell抑制因子 … More / 免疫療法 / single cell RNA sequence / 免疫チェックポイント阻害薬 / 末端黒子型メラノーマ / 粘膜型メラノーマ / tumor digest / 腫瘍浸潤リンパ球 / 腫瘍特異的CTL / 癌免疫 / MHC classII / PD-L1 / LAG-3 / 免疫チェックポイント阻害剤 / LAG3 / 抗CTLA-4抗体 / NGF / CD271 / CD226 / 国際情報交流 / 腫瘍免疫 / 皮膚腫瘍学 / 蛋白導入ドメイン / マウス / ワクチン / 癌抗原 / B細胞リンパ腫 / gp100 / CTL / gP100 / ペプチド / HLA-A2 / 日本人 … More
Except Principal Investigator
メラノーマ / 免疫チェックポイント / 悪性黒色腫 / 腫瘍免疫 / がん免疫療法 / 免疫療法 / TIL / 非動物実験モデル / がん関連線維芽細胞 / LH2 / 免疫記憶 / 免疫エスケープ / 腫瘍特異的CTL / CD109 / CD276 / バイオマーカー / 腫瘍特異的T細胞 / 抗PD-1抗体 / 免疫ゲノム解析 / 免疫チェックポイント阻害薬 / 腫瘍浸潤リンパ球 / 重粒子線治療 / 主要組織適合抗原複合体クラスI(MHC-I) / インターフェロンγ / 粘膜型悪性黒色腫 / 抗腫瘍活性 / 免疫疲弊 / 細胞接着 / Cell adhesion / Melanoma / Cancer immunology / 治療抵抗性 / Timp3 / Nupr1 / AID / がん免疫 / STAT3 / 癌免疫療法 / 皮膚腫瘍 / ワクチン Less
  • Research Projects

    (17 results)
  • Research Products

    (99 results)
  • Co-Researchers

    (24 People)
  •  irAE白斑をモデルとした抗腫瘍効果と自己免疫を差別化するための基盤研究Principal Investigator

    • Principal Investigator
      猪爪 隆史
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Chiba University
  •  Comparative analysis of immunological memory against cancers

    • Principal Investigator
      谷口 智憲
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto University
  •  がん関連stiff-collagen制御機構の解明を基盤とした新規がん免疫強化治療戦略の開拓

    • Principal Investigator
      鵜澤 一弘
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Chiba University
  •  メラノーマに対する免疫反応を評価する定量的非動物モデルの確立と新規治療標的の検証

    • Principal Investigator
      川原 祐
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Chiba University
  •  抗PD-1抗体への獲得耐性に関わる候補分子CD109とCD276の機能解析

    • Principal Investigator
      松澤 高光
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Chiba University
  •  免疫チェックポイント阻害剤の課題克服を目指した腫瘍特異的T細胞の解析Principal Investigator

    • Principal Investigator
      猪爪 隆史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Chiba University
  •  Functional analysis of a novel cell adhesion molecule expressed in the exhausted T cells infiltrated to melanoma

    • Principal Investigator
      Morinaga Takao
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Analysis of the immuno-genome and the effects of heavy ion therapy on mucosal melanoma of the nasal cavity and paranasal sinuses

    • Principal Investigator
      Hanazawa Toyoyuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Chiba University
  •  Identification of biomarkers that accurately predict the effect of anti-PD-1 therapyPrincipal Investigator

    • Principal Investigator
      Inozume Takashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Chiba University
      University of Yamanashi
  •  Identification of novel immunecheckpoints and development of methods to inhibit themPrincipal Investigator

    • Principal Investigator
      Inozume Takashi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
  •  Identification of the sub-population in human malignant melanoma showing strong resistance to tumor specific cytotoxic T cells

    • Principal Investigator
      Yaguchi Tomonori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Keio University
  •  Development of an innovative, simple system to detect the critical gene mutations of skin cancers

    • Principal Investigator
      SHIMADA Shinji
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
  •  Development of a novel therapy for melanoma that inhibits T cell suppressive moleculesPrincipal Investigator

    • Principal Investigator
      INOZUME Takashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
  •  Analyses for the establishment of the effective immunotherapy to melanoma-bearing hosts

    • Principal Investigator
      SHIBAGAKI Naotaka
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
  •  Identification of novel immune-suppressive factors on melanoma cellsPrincipal Investigator

    • Principal Investigator
      INOZUME Takashi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
  •  メラノーマとB細胞系に特異的に高発現する分子M266を用いた免疫療法の開発Principal Investigator

    • Principal Investigator
      猪爪 隆史
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
  •  日本人に頻度が高いHLA-A2サブタイプに提示されるメラノーマ抗原の同定Principal Investigator

    • Principal Investigator
      猪爪 隆史
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Yamanashi
      山梨医科大学

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2005 Other

All Journal Article Presentation Book

  • [Book] 癌と免疫  第2部 15,がん免疫における共刺激分子、共抑制分子と免疫チェックポイント2015

    • Author(s)
      猪爪隆史、島田眞路
    • Total Pages
      9
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-26670522
  • [Book] 癌と免疫  第2部 15,がん免疫における共刺激分子、共抑制分子と免疫チェックポイント2015

    • Author(s)
      猪爪隆史、島田眞路
    • Total Pages
      9
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Journal Article] メラノーマにおける研究と診療の進歩2024

    • Author(s)
      猪爪隆史
    • Journal Title

      医学のあゆみ

      Volume: 289 Pages: 24913-24917

    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Journal Article] Amelanotic melanoma in oculocutaneous albinism type 4 detected using violet‐light dermoscopy2024

    • Author(s)
      Kameda Eisuke、Matsuzawa Takamitsu、Togawa Yaei、Hashimoto Rei、Saito Toru、Suzuki Tamio、Inozume Takashi
    • Journal Title

      The Journal of Dermatology

      Volume: ahead of print Issue: 8

    • DOI

      10.1111/1346-8138.17164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08374
  • [Journal Article] Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment2024

    • Author(s)
      Zhou W, Kawashima S, Ishino T, Kawase K, Ueda Y, Yamashita K, Watanabe T, Kawazu M, Dansako H, Suzuki Y, Nishikawa H, Inozume T, Nagasaki J, Togashi Y.
    • Journal Title

      Cell Reports

      Volume: - Issue: 2 Pages: 113797-113797

    • DOI

      10.1016/j.celrep.2024.113797

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14594, KAKENHI-PROJECT-23KK0149, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-22K19459, KAKENHI-PROJECT-22K15472, KAKENHI-PROJECT-22K20824, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-21H02772
  • [Journal Article] CD106 in tumor-specific exhausted CD8+ T cells mediates immunosuppression by inhibiting TCR signaling2024

    • Author(s)
      Naoi Y, Morinaga T, Nagasaki J, Ariyasu R, Ueda Y, Yamashita K, Zhou W, Kawashima S, Kawase K, Honobe-Tabuchi A, Ohnuma T, Kawamura T, Umeda Y, Kawahara Y, Nakamura Y, Kiniwa Y, Yamasaki O, Fukushima S, Kawazu M, Suzuki Y, Nishikawa H, Hanazawa T, Ando M, Inozume T, Togashi Y.
    • Journal Title

      Cancer Research

      Volume: - Issue: 13 Pages: 2109-2122

    • DOI

      10.1158/0008-5472.can-23-0453

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14594, KAKENHI-PROJECT-23K07765, KAKENHI-PROJECT-21K08314
  • [Journal Article] High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects2023

    • Author(s)
      Kawase K、Kawashima S、Nagasaki J、Inozume T、Tanji E、Kawazu M、Hanazawa T、Togashi Y
    • Journal Title

      Cancer Immunology Research

      Volume: In press Issue: 7 Pages: 895-908

    • DOI

      10.1158/2326-6066.cir-22-0815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-23K15261, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-21K09625, KAKENHI-PROJECT-22K19459, KAKENHI-PROJECT-22K20824, KAKENHI-PROJECT-21H02772
  • [Journal Article] A case of metallosis mimicking cutaneous malignant melanoma following total elbow arthroplasty2023

    • Author(s)
      Arima Mio, Matsuzawa Takamitsu, Hashimoto Eiko, Ochiai Nobuyasu, Matsusaka Keisuke, Inozume Takashi
    • Journal Title

      JEADV Clinical Practice

      Volume: 2 Issue: 2 Pages: 343-346

    • DOI

      10.1002/jvc2.131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06936, KAKENHI-PROJECT-22K08374
  • [Journal Article] Clues for developing next‐generation cancer immunotherapy2023

    • Author(s)
      Inozume Takashi、Fukushima Satoshi
    • Journal Title

      Experimental Dermatology

      Volume: 32 Issue: 3 Pages: 238-239

    • DOI

      10.1111/exd.14751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-21K08351
  • [Journal Article] Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study2023

    • Author(s)
      Inozume Takashi、Namikawa Kenjiro、Kato Hiroshi、Yoshikawa Shusuke、Kiniwa Yukiko、Yoshino Koji、Mizuhashi Satoru、Ito Takamichi、Takenouchi Tatsuya、Matsushita Shigeto、Fujisawa Yasuhiro、Matsuzawa Takamitsu、et al.
    • Journal Title

      Journal of Dermatological Science

      Volume: 110 Issue: 1 Pages: 19-26

    • DOI

      10.1016/j.jdermsci.2023.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K08374, KAKENHI-PROJECT-22K08424
  • [Journal Article] 黒色腫治療における全身薬物療法の新しい標的分子2023

    • Author(s)
      猪爪隆史
    • Journal Title

      皮膚科

      Volume: 3 Pages: 701-706

    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Journal Article] Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration2022

    • Author(s)
      T. Morinaga, T. Inozume, Y. Togashi et al.
    • Journal Title

      Cancer Research Communications

      Volume: 2 Issue: 7 Pages: 739-753

    • DOI

      10.1158/2767-9764.crc-22-0050

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08314, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-22K19459, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772
  • [Journal Article] PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes2022

    • Author(s)
      Nagasaki Joji、Inozume Takashi、Yosuke Togashi et al.
    • Journal Title

      Cell Reports

      Volume: 38 Issue: 5 Pages: 110331-110331

    • DOI

      10.1016/j.celrep.2022.110331

    • NAID

      120007192058

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-21K07112, KAKENHI-PROJECT-21K08152, KAKENHI-PROJECT-21K08314, KAKENHI-PROJECT-21K12117, KAKENHI-PROJECT-21K09625, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-22H00455
  • [Journal Article] Efficacy comparison between anti-PD-1 antibody monotherapy and anti-PD-1 plus anti-CTLA-4 combination therapy as first-line immunotherapy for advanced acral melanoma: A retrospective, multicenter study of 254 Japanese patients2022

    • Author(s)
      Nakamura Yasuhiro、Namikawa Kenjiro、Kiniwa Yukiko、Kato Hiroshi、Yamasaki Osamu、Yoshikawa Shusuke、Maekawa Takeo、Matsushita Shigeto、Takenouchi Tatsuya、Inozume Takashi、Nakai Yasuo、Fukushima Satoshi、et al.
    • Journal Title

      European Journal of Cancer

      Volume: 176 Pages: 78-87

    • DOI

      10.1016/j.ejca.2022.08.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08351, KAKENHI-PROJECT-22K08424, KAKENHI-PROJECT-20K08652
  • [Journal Article] PD-L1 on mast cells suppresses effector CD8+ T-cell activation in the skin in murine contact hypersensitivity2021

    • Author(s)
      Hirano Tomoko、Honda Tetsuya、Kanameishi Shuto、Honda Yuki、Egawa Gyohei、Kitoh Akihiko、Nakajima Saeko、Otsuka Atsushi、Nomura Takashi、Dainichi Teruki、Yaguchi Tomonori、Inozume Takashi、Kataoka Tatsuki R.、Tamada Koji、Kabashima Kenji
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: in press Issue: 2 Pages: 00178-00178

    • DOI

      10.1016/j.jaci.2020.12.654

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-19K08748, KAKENHI-PROJECT-15H05790, KAKENHI-PROJECT-19K08790, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K08303
  • [Journal Article] TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment2021

    • Author(s)
      Kawashima S, Inozume T, Kawazu M, Ueno T, Nagasaki J, Tanji E, Honobe A, Ohnuma T, Kawamura T, Umeda Y, Nakamura Y, Kawasaki T, Kiniwa Y, Yamasaki O, Fukushima S, Ikehara Y, Mano H, Suzuki Y, Nishikawa H, Matsue H, Togashi Y.
    • Journal Title

      Journal for ImmunoTherapy of Cancer

      Volume: 9 Issue: 11 Pages: e003134-e003134

    • DOI

      10.1136/jitc-2021-003134

    • NAID

      120007175403

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-21H02772, KAKENHI-PROJECT-20K08652, KAKENHI-PROJECT-21K06910, KAKENHI-PROJECT-21K08351, KAKENHI-PROJECT-21K12117
  • [Journal Article] Mutant KRAS Promotes NKG2D+ T Cell Infiltration and CD155 Dependent Immune Evasion2020

    • Author(s)
      NISHI KENSUKE、ISHIKURA SHUHEI、UMEBAYASHI MASAYO、MORISAKI TAKASHI、INOZUME TAKASHI、KINUGASA TETSUSHI、AOKI MIKIKO、NIMURA SATOSHI、SWAIN ANTHONY、YOSHIDA YOICHIRO、HASEGAWA SUGURU、NABESHIMA KAZUKI、SAKATA TOSHIFUMI、SHIRASAWA SENJI、TSUNODA TOSHIYUKI
    • Journal Title

      Anticancer Research

      Volume: 40 Issue: 8 Pages: 4663-4674

    • DOI

      10.21873/anticanres.14465

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-20K09114, KAKENHI-PROJECT-18K07215
  • [Journal Article] メラノーマの新たな治療標的2020

    • Author(s)
      猪爪隆史
    • Journal Title

      生体の科学

      Volume: 71 Pages: 602-607

    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Journal Article] Concordance and Discordance Rates of V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600E Status in Metastatic against Primary Lesion of Melanoma: A Meta-analysis2020

    • Author(s)
      Yokomichi H, Inozume T, Wada M, Asai J, Igaki H, Namikawa K, et al.
    • Journal Title

      JMA Journal

      Volume: 3 Issue: 3 Pages: 274-279

    • DOI

      10.31662/jmaj.2020-0016

    • NAID

      130007905834

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-19K10658, KAKENHI-PROJECT-18K17376, KAKENHI-PROJECT-18K08301, KAKENHI-PROJECT-18K09492
  • [Journal Article] Heterogeneity in congenital melanocytic nevi contributes to multicentric melanomagenesis2020

    • Author(s)
      Honobe Akiko、Sakai Kazuko、Togashi Yosuke、Ohnuma Takehiro、Kawamura Tatsuyoshi、Nishio Kazuto、Inozume Takashi
    • Journal Title

      Journal of Dermatological Science

      Volume: 100 Issue: 3 Pages: 217-219

    • DOI

      10.1016/j.jdermsci.2020.09.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-19K17794
  • [Journal Article] Analysis of the tumor reactivity of tumor-infiltrating lymphocytes in a metastatic melanoma lesion that lost MHC class I expression after anti-PD-1 therapy.2019

    • Author(s)
      Inozume T, Yaguchi T, Ariyasu R, Togashi Y, Ohnuma T, Honobe A, Nishikawa H, Kawakami Y, Kawamura T.
    • Journal Title

      J Invest Dermatol.

      Volume: 印刷中 Issue: 7 Pages: 30023-5

    • DOI

      10.1016/j.jid.2019.01.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08309, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-16K10148, KAKENHI-PROJECT-17K16335, KAKENHI-PROJECT-17K18388, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-19K08744, KAKENHI-PROJECT-19K17794
  • [Journal Article] Acquisition of resistance to vemurafenib leads to interleukin-10 production through an aberrant activation of Akt in a melanoma cell line2018

    • Author(s)
      Inozume T, Tsunoda T, Morisaki T, Harada K, Shirasawa S, Kawamura T
    • Journal Title

      Journal of Dermatology

      Volume: 45 Issue: 12 Pages: 1434-1439

    • DOI

      10.1111/1346-8138.14651

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10148, KAKENHI-PROJECT-18K07215
  • [Journal Article] Cytotoxic T-lymphocyte-associated protein 4 expressed by melanoma cells does not affect melanoma-specific cytotoxic T lymphocytes in the effector phase2018

    • Author(s)
      Inozume Takashi、Hanada Ken-ichi、Takeda Kazuyo、Maeda Tatsuo、Harada Kazutoshi、Kawamura Tatsuyoshi
    • Journal Title

      The Journal of Dermatology

      Volume: 46 Issue: 1 Pages: 52-56

    • DOI

      10.1111/1346-8138.14685

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10256, KAKENHI-PROJECT-16K10148
  • [Journal Article] Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses2017

    • Author(s)
      Yaguchi Tomonori、Kobayashi Asuka、Inozume Takashi、Morii Kenji、Nagumo Haruna、Nishio Hiroshi、Iwata Takashi、Ka Yuyo、Katano Ikumi、Ito Ryoji、Ito Mamoru、Kawakami Yutaka
    • Journal Title

      Cell Mol Immunol.

      Volume: 印刷中 Issue: 11 Pages: 1-10

    • DOI

      10.1038/cmi.2017.106

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07103, KAKENHI-PROJECT-16K10148, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-15K09783
  • [Journal Article] Increased Soluble CD226 in Sera of Patients with Cutaneous T-Cell Lymphoma Mediating Cytotoxic Activity against Tumor Cells via CD155.2017

    • Author(s)
      Takahashi N, Sugaya M, Suga H, Oka T, Kawaguchi M, Miyagaki T, Fujita H, Inozume T, Sato S.
    • Journal Title

      Journal of Investigative Dermatology

      Volume: in press Issue: 8 Pages: 1766-1773

    • DOI

      10.1016/j.jid.2017.03.025

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10146, KAKENHI-PROJECT-16K10148
  • [Journal Article] Melanoma cells control anti-melanoma CTL responses via interaction between TIGIT and CD155 in the effector phase.2016

    • Author(s)
      Inozume T, Yaguchi T, Furuta F, Harada K, Kawakami Y, Shimada S.
    • Journal Title

      J Invest Dermatol.

      Volume: 136 Issue: 1 Pages: 255-263

    • DOI

      10.1038/jid.2015.404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09783, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-25461687, KAKENHI-PROJECT-26670522
  • [Journal Article] メラノーマに対する免疫療法の開発2015

    • Author(s)
      猪爪隆史
    • Journal Title

      山梨医科学雑誌

      Volume: 30 Pages: 7-13

    • NAID

      110009889061

    • Data Source
      KAKENHI-PROJECT-25461687
  • [Journal Article] 新規免疫チェックポイントの可能性2015

    • Author(s)
      猪爪隆史
    • Journal Title

      最新医学

      Volume: 70 Pages: 378-385

    • Data Source
      KAKENHI-PROJECT-25461687
  • [Journal Article] 進行期メラノーマ治療update2015

    • Author(s)
      猪爪隆史
    • Journal Title

      日本臨床皮膚科医会雑誌

      Volume: 32 Pages: 017-022

    • Data Source
      KAKENHI-PROJECT-25461687
  • [Journal Article] CD271 on Melanoma Cell Is an IFN-γ-Inducible Immunosuppressive Factor that Mediates Downregulation of Melanoma Antigens.2014

    • Author(s)
      Furuta J, Inozume T, Harada K, Shimada S.
    • Journal Title

      J Invest Dermatol.

      Volume: 134 Issue: 5 Pages: 1369-1377

    • DOI

      10.1038/jid.2013.490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591614, KAKENHI-PROJECT-25461687
  • [Journal Article] 悪性黒色腫に対する免疫療法2014

    • Author(s)
      猪爪隆史
    • Journal Title

      産科と婦人科

      Volume: 81 Pages: 223-230

    • Data Source
      KAKENHI-PROJECT-25461687
  • [Journal Article] A NOVEL MELANOMA ANTIGEN, FCRL/FREB, IDENTIFIED BY cDNA PROFILE COMPARISON USING DNA CHIP ARE IMMUNOGENIC IN MULTIPLE MELANOMA PATIENTS2005

    • Author(s)
      Takashi Inozume et al.
    • Journal Title

      International Journal of Cancer 114

      Pages: 283-290

    • Data Source
      KAKENHI-PROJECT-16790631
  • [Presentation] 進行期メラノーマに伴う白斑2023

    • Author(s)
      猪爪隆史
    • Organizer
      第5回日本白斑学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] ゲノム検査に基づいた皮膚がん治療2023

    • Author(s)
      猪爪隆史
    • Organizer
      第39回日本皮膚悪性腫瘍学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] BRAF陰性露光部悪性黒色腫に対する抗PD-1抗体と抗PD-1抗体+抗CTLA-4抗体併用療法の効果2023

    • Author(s)
      猪爪隆史、並川健二郎、加藤裕志、木庭幸子、吉野公二、伊東孝通、水橋覚、吉川周佐、宇原久、中村泰大
    • Organizer
      第39回日本皮膚悪性腫瘍学会
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] メラノーマ周術期における免疫チェックポイント阻害剤(ICI)治療の現状と課題: 最適化のためのヒントと必要な研究2023

    • Author(s)
      猪爪隆史
    • Organizer
      第27回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] High major histocompatibility complex class I expression overcomes cancer immunotherapy resistance due to interferon gamma signaling pathway defects.2023

    • Author(s)
      Kawase K, Kawashima S, Nagasaki J, Inozume T, Yamamoto H, Kawazu M, Hanazawa T, Togashi Y.
    • Organizer
      AACR Annual Meeting 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09625
  • [Presentation] Increasing MHC class I expression is crucial for antitumor immunity among IFNγ signaling pathways.2023

    • Author(s)
      Kawase K, Kawashima S, Nagasaki J, Inozume T, Kawazu M, Hanazawa T, Togashi Y.
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K09625
  • [Presentation] 抗PD-1抗体著効例における腫瘍浸潤T細胞と白斑に浸潤するT細胞の解析2023

    • Author(s)
      青山和弘、佐伯優佳、斎藤宜子、河津正人、冨樫庸介、川島秀介、猪爪隆史
    • Organizer
      第5回日本白斑学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] PD-1 blockade may promote not only the reactivation of preexisting tumor-specific T cell clones but also the infiltration of new clones2023

    • Author(s)
      Inozume T, Nagasaki J, Kawazu M, Kawamura T, Yamashita K, Togashi Y
    • Organizer
      International Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] 後頭部に生じたdesmoplastic malignant melanomaの1例2022

    • Author(s)
      平山美歩, 松澤高光, 外川八英, 松坂 恵介, 安齋眞一, 猪爪 隆史
    • Organizer
      第904回日本皮膚科学会東京地方会
    • Data Source
      KAKENHI-PROJECT-22K08374
  • [Presentation] オルガノイド技術を応用した露光部皮膚がんに対する免疫反応を評価するシステムの確立2022

    • Author(s)
      猪爪隆史
    • Organizer
      第18回加齢皮膚医学研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] Mixed response to cancer immunotherapy is driven by intratumor heterogeneity and differential inter-lesion immune infiltration2022

    • Author(s)
      Takashi Inozume, Takao Morinaga, Masahito Kawazu, Shusuke Kawashima, Takehiro Ohnuma, Yukiko Kiniwa, Yu Kawahara, Yoshiyasu Umeda, Yasuhiro Nakamura, Tatsuyoshi Kawamura, Kazuo Yamashita, Yutaka Suzuki, Hiroyoshi Nishikawa, Yosuke Togashi
    • Organizer
      The 47th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] TILの個細胞解析から考えるニボ+イピ併用療法の意義2022

    • Author(s)
      猪爪隆史
    • Organizer
      第74回日本皮膚科学会 西部支部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] メラノーマに対するがん免疫療法2022

    • Author(s)
      猪爪隆史
    • Organizer
      第33回日本色素細胞学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K08424
  • [Presentation] メラノーマと腫瘍免疫2021

    • Author(s)
      猪爪隆史
    • Organizer
      第120回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Heterogeneity in congenital melanocytic nevi contributes to multicentric melanomagenesis2021

    • Author(s)
      Inozume Takashi et al.
    • Organizer
      第18回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] 抗PD-1抗体+抗CTLA-4抗体併用療法のエビデンスと意義2021

    • Author(s)
      猪爪隆史
    • Organizer
      第120回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Biological and immunological characteristics of melanoma subtypes predominant in Japan2021

    • Author(s)
      Takashi Inozume
    • Organizer
      The 36th annual meeting of the Japanese skin cancer society
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] メラノーマ病巣内でICIの効果に影響する因子の解析2021

    • Author(s)
      猪爪隆史
    • Organizer
      第49回臨床免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] 免疫チェックポイント阻害剤の作用機序とバイオマーカー2021

    • Author(s)
      猪爪隆史
    • Organizer
      第37回日本皮膚悪性腫瘍学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Biological and immunological characteristics of melanoma subtypes predominant in Japan2021

    • Author(s)
      Inozume Takashi
    • Organizer
      The 36th annual meeting of the Japanese skin cancer society
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Heterogeneity in congenital melanocytic nevi contributes to multicentric melanomagenesis2021

    • Author(s)
      猪爪隆史ら
    • Organizer
      第18回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] メリットデメリットのバランスで考えるメラノーマ治療2020

    • Author(s)
      猪爪隆史
    • Organizer
      第468回日本皮膚科学会北陸地方会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] メラノーマ研究と治療経験から考えるがん免疫療法2020

    • Author(s)
      猪爪隆史
    • Organizer
      第24回日本がん免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Identification and characterization of tumor-infiltrating lymphocytes that may mediate anti-tumor response by nivolumab2019

    • Author(s)
      Takashi Inozume, Yosuke Togashi, Ryo Ariyasu, Tomonori Yaguchi, Takehiro Ohnuma, Yutaka Kawakami, Hiroyoshi Nishikawa, Tatsuyoshi Kawamura
    • Organizer
      The 44th annual meeting of Japanese Society for Investigative Dermatology
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] 免疫抑制の観点から2019

    • Author(s)
      猪爪隆史
    • Organizer
      第57回日本癌治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Analysis of the tumor reactivity of tumor-infiltrating lymphocytes in a metastatic melanoma lesion that lost MHC class I expression after anti-PD-1 therapy2019

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Ryo Ariyasu, Yosuke Togashi, Takehiro Ohnuma, Akiko Honobe, Hiroyoshi Nishikawa, Yutaka Kawakami, Tatsuyoshi Kawamura
    • Organizer
      The 77 the annual meeting of Society for Investigative Dermatology
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] Important issues in melanoma treatment and research to solve them2019

    • Author(s)
      Takashi Inozume
    • Organizer
      The 29th Annual Meeting of the Japanese Society for Pigment Cell Research
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] 抗PD-1抗体が著効した進行期メラノーマ におけるTILの機能解析2019

    • Author(s)
      猪爪隆史, 冨樫庸介, 有安亮, 谷口智憲, 大沼毅紘, 河上裕, 西川博嘉
    • Organizer
      第23回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] 免疫チェックポイント阻害療法の 効率化に向けた研究2019

    • Author(s)
      猪爪隆史
    • Organizer
      第118回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K08744
  • [Presentation] 抗PD-1抗体、抗CTLA-4抗体とその先2018

    • Author(s)
      猪爪隆史
    • Organizer
      第34回日本皮膚悪性腫瘍学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] 抗PD-1抗体、抗CTLA-4抗体の可能性と限界を考える2018

    • Author(s)
      猪爪隆史
    • Organizer
      第82回日本皮膚科学会東京支部学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] 免疫チェックポイント阻害剤の理解に役立つがん免疫の知識2018

    • Author(s)
      猪爪隆史
    • Organizer
      第70回日本皮膚科学会西部支部学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] 抗PD-1抗体により長期安定後に悪化した病巣のメラノーマ細胞とTILの解析2018

    • Author(s)
      猪爪隆史、谷口智憲、大沼毅紘、河上裕、川村龍吉
    • Organizer
      第22回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] Identification of suitable immune checkpoints as targets for cancer immunotherapy2017

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Junpei Furuta, Kazutoshi Harada, Yutaka Kawakami, Shinji Shimada
    • Organizer
      The 42nd annual Meeting of the Japanese Society for Investigative Dermatology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] 4-1BB刺激は免疫チェックポイント阻害と相乗的にメラノーマ特異的CTLの活性を増強する2017

    • Author(s)
      猪爪隆史、谷口智憲、河上裕
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-15K09783
  • [Presentation] 次の免疫チェックポイント分子2017

    • Author(s)
      猪爪隆史
    • Organizer
      第38回日本炎症、再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] CTLA-4 expressed by melanoma cells showed enhanced susceptibility to anti-melanoma T-cell responses2017

    • Author(s)
      Takashi Inozume, Kazutoshi Harada, Tatsuyoshi Kawamura, Shinji Shimada
    • Organizer
      The 42nd annual Meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] Activation of 4-1BB signal and co-blockade of PD-1 and TIGIT signaling synergistically enhance melanoma-specific CTL responses during the effector phase2017

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Tatsuyoshi Kawamura, Yutaka Kawakami, Ken-ichi Hanada, Shinji Shimada
    • Organizer
      76th annual meeting of Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] 癌免疫療法の現状と課題2016

    • Author(s)
      猪爪隆史
    • Organizer
      東葛北部がん治療、支持療法フォーラム
    • Place of Presentation
      柏の葉カンファレンスセンター、千葉県、柏市
    • Year and Date
      2016-03-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] PD-1, TIGIT, and LAG-3 signals synergistically suppress the anti-melanoma CTL response in the effector phase2016

    • Author(s)
      Takashi Inozume
    • Organizer
      The 41st annual meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-12-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] Blockade of multiple immune checkpoints cooperatively enhanced the antitumor effect of melanoma-specific CTLs2016

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Junpei Furuta, Mamoru Itoh, Yutaka Kawakami, Shinji Shimada
    • Organizer
      Society for Investigative Dermatology 75th annual meeting
    • Place of Presentation
      Westin Kierland, Scottsdale, Arizona (USA)
    • Year and Date
      2016-05-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10148
  • [Presentation] Co-blockade of TIGIT and PD-1 signals in tumor-infiltrating cytotoxic T lymphocytes is an effective antimelanoma therapy2015

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Junpei Furuta, Kazutoshi Harada, Yutaka Kawakami, Shinji Shimada
    • Organizer
      第40回日本研究皮膚科学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-15K09783
  • [Presentation] メラノーマに対する免疫療法の現状と展望 -進行期メラノーマを免疫療法で治癒 させられるか-2015

    • Author(s)
      猪爪隆史
    • Organizer
      免疫チェックポイント阻害薬適正使用セミナー
    • Place of Presentation
      信州大学、長野県、松本
    • Year and Date
      2015-11-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] 抗PD-1抗体療法の成功から見えてきた癌免疫療法の展望2015

    • Author(s)
      猪爪隆史
    • Organizer
      第6回JBCRG学術集会
    • Place of Presentation
      京都リサーチパーク バズホール、京都府、下京区
    • Year and Date
      2015-11-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] CD155-TIGIT interaction is an immune checkpoint regulating antimelanoma TIL responses2015

    • Author(s)
      Inozume Takashi, Yaguchi Tomonori, Kawakami Yutaka, Shimada Shinji
    • Organizer
      がん免疫療法・マクロファージ国際会議2015
    • Place of Presentation
      東京大学伊藤国際学術センター内伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2015-07-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09783
  • [Presentation] Blockade for CD155-TIGIT interaction is an effective therapy for melanoma2015

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami, Shinji Shimada
    • Organizer
      Society for Investigative Dermatology, 2015, annual meeting
    • Place of Presentation
      Hilton Atlanta, Atlanta, Georgia
    • Year and Date
      2015-05-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] Co-blockade of TIGIT and PD-1 signals in tumor-infiltrating cytotoxic T lymphocytes is an effective anti-melanoma therapy2015

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami, Shinji Shimada
    • Organizer
      The 40th annual meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      岡山コンベンションセンター, 岡山県、北区
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] CD155/TIGITシグナルは悪性黒色腫において腫瘍抗原特異的T細胞応答をエフェクターフェーズで制御する2015

    • Author(s)
      谷口智憲、猪爪隆史、古田潤平、原田和俊、島田眞路、河上裕
    • Organizer
      第43回日本臨床免疫学会総会,
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-15K09783
  • [Presentation] Co-blockade of TIGIT and PD-1 signals in tumor-infiltrating cytotoxic T lymphocytes is an effective anti-melanoma therapy2015

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami, Shinji Shimada
    • Organizer
      The 40th annual meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      岡山コンベンションセンター, 岡山県、北区
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670522
  • [Presentation] CD155-TIGIT interaction is an immune checkpoint regulating anti melanoma TIL responses2015

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami, Shinji Shimada
    • Organizer
      がん免疫、マクロファージ国際会議2015
    • Place of Presentation
      東京大学伊藤謝恩ホール、東京都、文京区
    • Year and Date
      2015-07-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] Blockade for CD155-TIGIT interaction is an effective therapy for melanoma2015

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Yutaka Kawakami, Shinji Shimada
    • Organizer
      Society for Investigative Dermatology, 2015, annual meeting
    • Place of Presentation
      Hilton Atlanta, Atlanta, Georgia
    • Year and Date
      2015-05-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670522
  • [Presentation] Recent Development in Cancer Immunotherapy2015

    • Author(s)
      Takashi Inozume
    • Organizer
      14th International Workshop on Langerhans Cells
    • Place of Presentation
      京都市国際交流会館、京都府、左京区
    • Year and Date
      2015-11-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] 進行期メラノーマは治癒できるか2014

    • Author(s)
      猪爪隆史
    • Organizer
      新潟がん免疫療法セミナー
    • Place of Presentation
      ホテル日航新潟、新潟県、新潟市
    • Year and Date
      2014-11-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] Development of a novel immunotherapy for melanoma which inhibits interaction between CD155 on melanoma cells and TIGIT on activated CTL2013

    • Author(s)
      Takashi Inozume, Junpei Furuta, Kazutoshi Harada, Tomonori Yaguchi, Yutaka Kawakami, Shinji Shimada
    • Organizer
      International Investigative Dermatology
    • Place of Presentation
      Edinburgh International Conference Center (The Exchange Edinburg EH3 8EE, Scotland)
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] Enhanced NGFR signal inmelanoma cells suppresses the tumorrecognition by melanoma specific T cells.2012

    • Author(s)
      猪爪隆史
    • Organizer
      2012 SID annual meeting and 75thanniversary celebration
    • Place of Presentation
      Raleighconventional center, Raleigh, NorthCarolina, USA
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] CD155はほぼすべてのメラノーマ細胞株に発現されメラノーマ特異的CTLの活性化を直接に抑制する2012

    • Author(s)
      猪爪隆史
    • Organizer
      第16回日本がん免疫学会総会
    • Place of Presentation
      北海道大学学術交流会館(北海道)
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] Enhanced NGFR signal in melanoma cells suppresses the tumor recognition by melanoma specific T cells2012

    • Author(s)
      Takashi Inozume
    • Organizer
      2012 SID annual meeting and 75th anniversary celebration
    • Place of Presentation
      Raleigh convention center (Raleigh)
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] CD155 is highly expressed bymelanoma tissues and it suppresses theactivation of melanoma specific CTLs viainteraction with TIGIT2012

    • Author(s)
      猪爪隆史
    • Organizer
      The 37thannual meeting of the Japanesesociety for investigative dermatology
    • Place of Presentation
      ロワジールホテル那覇、沖縄
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] CD155 はほぼすべてのメラノーマ細胞株に発現され、メラノーマ特異的 CTLの活性化を直接に抑制する2012

    • Author(s)
      猪爪隆史
    • Organizer
      第16回日本がん免疫学会総会
    • Place of Presentation
      北海道大学学術交流会館、北海道
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] CD155 is highly expressed by melanoma tissues and it suppresses the activation of melanoma specific CTLs via interaction with TIGIT2012

    • Author(s)
      Takashi Inozume
    • Organizer
      The 37th annual meeting of the Japanese society for investigative dermatology
    • Place of Presentation
      ロワジールホテル那覇(沖縄)
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] NGFR is up-regulated onmelanoma cells by IFNg stimulation and itsuppressed the tumor recognition by tumorspecific T cells2011

    • Author(s)
      猪爪隆史
    • Organizer
      The 36thannual meeting of the Japanesesociety for investigative dermatology
    • Place of Presentation
      京都国際会議場、京都
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] NGFRはIFN-g刺激でメラノーマ細胞上に発現増強されメラノーマ特異的T細胞からの認識を抑制する

    • Author(s)
      Takashi Inozume
    • Organizer
      第36回日本研究皮膚科学会
    • Place of Presentation
      京都国際会議場(京都府)
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] NGFRはIFN-g刺激でメラノーマ細胞上に発現増強されメラノーマ特異的T細胞からの認識を抑制する

    • Author(s)
      猪爪隆史
    • Organizer
      第15回日本がん免疫学会総会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府)
    • Data Source
      KAKENHI-PROJECT-23791261
  • [Presentation] Blockade fro CD155-TIGIT interaction elicits anti-melanoma T cell responses in vitro and in vivo

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Junpei Furuta, Mamoru Itoh, Yutaka Kawakami, Shinji Shimada
    • Organizer
      The 39th annual meeting of the Japanese society for Investigative Dermatology
    • Place of Presentation
      Hotel Hankyu Expopark (Osaka, Japan)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] 高頻度遺伝子変異導入システムを利用したメラノーマ治療の成否を左右する重要因子の検索

    • Author(s)
      猪爪隆史、原田和俊、島田眞路
    • Organizer
      第114回日本皮膚科学会総会
    • Place of Presentation
      パシフィコ横浜、神奈川県、横浜市
    • Year and Date
      2015-05-29 – 2015-05-31
    • Data Source
      KAKENHI-PROJECT-26670522
  • [Presentation] CD155-TIGIT interaction is an immune checkpoint regulating anti melanoma immune responses

    • Author(s)
      Takashi Inozume, Tomonori Yaguchi, Junpei Furuta, Kazutoshi Harada, Yutaka Kawakami, Shinji Shimada
    • Organizer
      2014 annual meeting of Society for Investigative Dermatology
    • Place of Presentation
      Albuquerque Convention Center, Albuquerque, New Mexico
    • Year and Date
      2014-05-07 – 2014-05-10
    • Data Source
      KAKENHI-PROJECT-25461687
  • [Presentation] CD155-TIGIT interaction is an immune checkpoint regulating anti melanoma immune responses

    • Author(s)
      猪爪隆史、谷口智憲、古田潤平、原田和俊、伊藤守、河上裕、島田眞路
    • Organizer
      第18回日本がん免疫学会
    • Place of Presentation
      ひめぎんホール、愛媛県、松山市
    • Year and Date
      2014-07-30 – 2014-08-01
    • Data Source
      KAKENHI-PROJECT-25461687
  • 1.  冨樫 庸介 (80758326)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 2.  Yaguchi Tomonori (40424163)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 3.  SHIBAGAKI Naotaka (40262662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  HANAWA Fumie (80535592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SHIMADA Shinji (10114505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  OKAMOTO Takashi (30402043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Morinaga Takao (30757000)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  Hanazawa Toyoyuki (90272327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  河上 裕 (50161287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  松澤 高光 (40568028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  鵜澤 一弘 (30302558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  池原 譲 (10311440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  本橋 新一郎 (60345022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  川原 祐 (80980713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  及川 綾子 (10422263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MATSUSAKA Keisuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  ITO Ryoji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  SHISHIDO NAOMI
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  OKA TOMONORI
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  FUKUSHIMA Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  原田 和俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 22.  菅谷 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  前 賢一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  長崎 譲慈
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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