OKAMOTO Koji 岡本康司

… Alternative Names

岡本康司オカモトコウジ

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Researcher Number	80342913
Other IDs
External Links
Affiliation (Current)	2025: 帝京大学, 先端総合研究機構, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 帝京大学, 先端総合研究機構, 教授 2015 – 2023: 国立研究開発法人国立がん研究センター, 研究所, 分野長 2016: 国立研究開発法人国立がん研究センター, その他部局等, その他 2015: 国立研究開発法人国立がん研究センター, 研究所及び東病院臨床開発センター, 分野長 2014: 独立行政法人国立がん研究センター, 研究所, 分野長 … More 2013: 国立がん研究センター研究所, 室長 2010 – 2012: 独立行政法人国立がん研究センター, 研究所, 分野長 2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 早期がん研究プロジェクト, 室長 2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所及び東病院臨床開発センター・早期がん研究プロジェクト, 室長 2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 放射線研究部, 室長 2003: 国立がんセンター研究所, 放射線研究部, 室長 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 56040:Obstetrics and gynecology-related / Complex systems / Tumor biology / Biological Sciences / General medical chemistry / Biological Sciences Except Principal Investigator Basic Section 50010:Tumor biology-related / Broad Section I / Tumor biology / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator 癌 / p53 / シングルセル解析 / 空間的トランスクリプトーム / 卵巣明細胞がん / 組織空間的解析 / がん組織多様性 / がん治療抵抗性 / 幹細胞 / 分子腫瘍学 … More / 転移 / がん転移 / かん幹細胞 / がん幹細胞 / neuron / neuroblastoma / cancer / Mdm2 / Mdmx / シグナル伝達 / 分子生物学 / リン酸化 / MDM2 / 発癌 … More Except Principal Investigator がん幹細胞 / トリプルネガティブ乳がん / PDX / 遺伝子発現 / 1細胞 / シングルセル / 乳がん / 転移がん / Drug tolerant persisters / トランスクリプトーム / ゲノム解析 / 治療抵抗性 / 不均一性 / 抗腫瘍薬 / 発がん実験 / 蛋白質翻訳 / ストレス応答 / 腫瘍悪性化 / ストレス反応 / がん細胞悪性化 / 蛋白質恒常性 / 弱いストレス / HIRA / RACK1 / 翻訳 / 転写 / 獲得耐性 / ストレス / １細胞 / ゲノム変異 / ニューロピリン / セマフォリン / IGF / スフェロイド / PDXモデル / neuropilin / スフェロイド培養 / 幹細胞 / RNAシークエンス / semaphoring, neuropilin / breast cancer, / cancer stem cells / Single cell / 発癌 / ストレス老化 / 癌化 / 解糖系代謝 / 老年医学 / 老化 Less

Single-cell level integrated elucidation of genomic gene mutation heterogeneity and stem cell hierarchy in breast cancer primary and metastasis
- Principal Investigator
  
  後藤典子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Integrated Elucidation of Genome Mutation Heterogeneity and Stem Cell Hierarchy in Breast Cancer at the Single-Cell Level
- Principal Investigator
  
  Gotoh Noriko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Elucidation of chemoresistant network of clear cell ovarian cancer via spatial analysesPrincipal Investigator
- Principal Investigator
  
  Okamoto Koji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Teikyo University
  National Cancer Center Japan
Anti-cancer therapies aiming for cure through inhibiting tumor-specific responses to environmental fluctuation
- Principal Investigator
  
  Ishikawa Fuyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kyoto University
Integrative analysis of genetical mutations and heterogeneity based on stemness in breast cancer cells
- Principal Investigator
  
  Gotoh Noriko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
個体モデルを用いた大規模シングルセル解析によるがん組織の要素還元論的な理解Principal Investigator
- Principal Investigator
  
  岡本康司
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  National Cancer Center Japan
Regulation epithelial stem cells by reactive oxgens species during oncogenic transformationPrincipal Investigator
- Principal Investigator
  
  Okamoto Koji
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  National Cancer Center Japan
Elucidation of breast cancer tissue diversity by integration analysis of minimum unit omics
- Principal Investigator
  
  Gotoh Noriko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Elucidation of chemoresistance of refracory cancer by single-cell gene expression analysesPrincipal Investigator
- Principal Investigator
  
  Okamoto Koji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Cancer Center Japan
がん転移制御因子の同定と解析を通じた臓器特異的な転移機構の解明Principal Investigator
- Principal Investigator
  
  岡本康司
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Japan
Senescence-inducing stress modulates glycolysis and the Warburg effect
- Principal Investigator
  
  KONDOH Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kyoto University
Regulation of cancer stem cells by MDMX/MDM2 oncoproteinsPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Koji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Center of Neurology and Psychiatry
Regulation of MDMX oncoprotein by genomic stressesPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Koji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Mdm2癌遺伝子産物による、p53癌抑制蛋白の制御機構Principal Investigator
- Principal Investigator
  
  岡本康司
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

[Journal Article] PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway2023
- Author(s)
  Ohata Hirokazu、Shiokawa Daisuke、Sakai Hiroaki、Kanda Yusuke、Okimoto Yoshie、Kaneko Syuzo、Hamamoto Ryuji、Nakagama Hitoshi、Okamoto Koji
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 6 Pages: 112519-112519
- DOI
  10.1016/j.celrep.2023.112519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-23K07467, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-21H03550
[Journal Article] 卵巣がん幹細胞の鍵シグナル2017
- Author(s)
  岡本康司
- Journal Title
  
  月刊「細胞」
  
  Volume: 49 Pages: 108-111
- Data Source
  KAKENHI-PROJECT-26293073
[Journal Article] 卵巣がん幹細胞の鍵シグナル2017
- Author(s)
  岡本康司
- Journal Title
  
  月刊「細胞」
  
  Volume: 49 Pages: 108-111
- Data Source
  KAKENHI-PROJECT-15K14390
[Journal Article] 卵巣がん幹細胞の鍵シグナル2017
- Author(s)
  岡本康司
- Journal Title
  
  月刊「細胞」
  
  Volume: 49 Pages: 108-111
- Data Source
  KAKENHI-PUBLICLY-16H01581
[Journal Article] Hepatocyte nuclear factor-1β promotes glucose uptake and glycolytic activity in ovarian clear carcinoma2013
- Author(s)
  T Okamoto, M Mandai, N Matsumura, K Yamaguchi, H Kondoh, Y Amano, T Baba, J Hamanishi, K Abiko, K Kosaka, S K, Murphy, S Mori, I Konishi
- Journal Title
  
  Molecular carcinogenesis
  
  Volume: Sep 17 Issue: 1 Pages: 1-15
- DOI
  10.1002/mc.22072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390186, KAKENHI-PROJECT-24791700, KAKENHI-PROJECT-24791701, KAKENHI-PROJECT-25670350, KAKENHI-PROJECT-25670703, KAKENHI-PROJECT-26253080
[Journal Article] miR-493 induction during carcinogenesis blocks metastatic settle merit of colon cancer cells in liver2012
- Author(s)
  Okamoto K., et al
- Journal Title
  
  EMBO Journal
  
  Volume: 31 Pages: 1752-1763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590299
[Journal Article] Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance ofcolon cancer-initiating cells2012
- Author(s)
  H. Ohata, T. Ishiguro, Y. Aihara, A. Sato, H. Sakai, S. Sekine, H. Taniguchi, T. Akasu, S. Fujita, H. Nakagama, K. Okamoto
- Journal Title
  
  Cancer Res
  
  Volume: 72 Pages: 5101-5110
- Data Source
  KAKENHI-PROJECT-22590299
[Journal Article] Differential expression of nanogl and nanogp8 in colon cancer cells2012
- Author(s)
  T. Ishiguro, A. Sato, H. Ohata, H. Sakai, H. Nakagama, K. Okamoto:
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 418 Pages: 199-204
- Data Source
  KAKENHI-PROJECT-22590299
[Journal Article] miR-493 induction during carcinogenesis blocks metastatic settlemerit of colon cancer cells in liver2012
- Author(s)
  Okamoto K., et al
- Journal Title
  
  EMBO Journal
  
  Volume: 31 Pages: 1752-1763
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112523
[Journal Article] miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver2012
- Author(s)
  K. Okamoto, T. Ishiguro, Y. Midorikawa, H. Ohata, M. Izumiya, N. Tsuchiya, A. Sato, H. Sakai, H. Nakagama
- Journal Title
  
  EMBO J
  
  Volume: 31 Pages: 1752-1763
- Data Source
  KAKENHI-PROJECT-22590299
[Journal Article] Systematic exploration of cancer-associated microRNA through functional screening assays2011
- Author(s)
  M. Izumiya, N. Tsuchiya, K. Okamoto, H. Nakagama
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1615-21
- NAID
  10030242740
- Data Source
  KAKENHI-PROJECT-22590299
[Journal Article] Tumor-suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p212011
- Author(s)
  N. Tsuchiya, M. Izumiya, H. Ogata-Kawata, K. Okamoto, Y. Fu j iwara, M. Nakai, A. Okabe, A. J. Schetter, E. D. Bowman, Y. Midorikawa, Y. Sugiyama, H. Aburatani, C. C. Harris, H. Nakagama
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 4628-4639
- Data Source
  KAKENHI-PROJECT-22590299
[Journal Article] Cytoplasmic Tethering is involved in Synergistic Inhibition of p53 by Mdmx and Mdm2.2009
- Author(s)
  C. Ohtsubo, D. Shiokawa, M. Kodama, C. Gaiddon, H. Nakagama, A. G. Jochemsen, Y. Taya, and K. Okamoto
- Journal Title
  
  Cancer Science
  
  Pages: 0-0
- NAID
  10027192333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590295
[Journal Article] Frequent inactivation of A20 in B-cell lymphomas.2009
- Author(s)
  M. Kato (the names of 21 authors omitted) K. Okamoto, K. Tobinai, H. Nakagama, T. Nakahata, T. Yoshino, Y. Kobayashi, and S. Ogawa
- Journal Title
  
  Nature in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590295
[Journal Article] Lysine-independent turnover of cyclin G1 can be stabilized by B'alpha subunits of protein phosphatase 2A.2009
- Author(s)
  H. Li, K. Okamoto, M. J. Peart, and C. Prives
- Journal Title
  
  Mol. Cell Biol. 29
  
  Pages: 919-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590295
[Journal Article] Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.2008
- Author(s)
  Y. Abe, E. Oda-Sato, K. Tobiume, K. Kawaguchi, Y. Taya, K. Okamoto, M. Oren, and N. Tanaka
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105
  
  Pages: 4838-4843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590295
[Journal Article] Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis.2007
- Author(s)
  S. Benosman, I. Gross, N. Clarke, A. G. Jochemsen, K. Okamoto, J. P. Loeffler, and C. Gaiddon
- Journal Title
  
  Cell Death & Differentiation 14
  
  Pages: 2047-2057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590295
[Patent] チロシンキナーゼ阻害剤によるがん関連線維芽細胞の抑制を介した卵巣明細胞がんの治療法の開発2023
- Inventor(s)
  森裕太郎、岡本康司
- Industrial Property Rights Holder
  森裕太郎、岡本康司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-188377
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] 肺がん由来スフェロイドパネルを用いた新たな治療標的の探索2022
- Author(s)
  岡本康司
- Organizer
  第63 回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] Functional role of mTORC1-mediated inhibition of autophagy in the regulation of slow-cycling persister cells of colon cancer2022
- Author(s)
  Koji Okamoto
- Organizer
  The protein phosphatase conference - Jointly hosted by FASEB and the Japanese Association for Protein Phosphatase Research (JAPPR)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] 凍結臨床検体を用いた1 細胞核解析と空間的トランスクリプトームの統合による卵巣明細胞腺がんの治療抵抗性の理解2022
- Author(s)
  森裕太郎、神田裕介、酒井宏晃、大畑広和、小幡裕希、塩川大介、吉田裕、Raul Nicolas Mateos、山脇芳、石黒竜也、吉原弘祐、白石友一、加藤友康、榎本隆之、岡本康司
- Organizer
  第4回がん三次元培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] シングルセル解析と空間的発現解析の統合によるがん難治性ネットワークの同定2022
- Author(s)
  Koji Okamoto
- Organizer
  日本患者由来がんモデル学会学術集会2022
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] 空間的発現解析によるがん難治性ネットワークの同定2022
- Author(s)
  岡本康司
- Organizer
  第10回Cancer Stem Cell Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] オートファジーによる PROX1の発現誘導は NOX1-mTORC1経路の抑制を介して休眠型の大腸がん細胞を生成する2022
- Author(s)
  大畑広和、塩川大介、岡本康司
- Organizer
  第81回日本癌学会国際シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] シングルセル解析と空間的トランスクリプトーム解析による卵巣明細胞腺癌の治療抵抗性ニッチの解明2022
- Author(s)
  森裕太郎、岡本康司、神田裕介、石黒竜也、吉原弘祐、榎本隆之、山脇芳、大畑広和、塩川大介
- Organizer
  第81回日本癌学会国際シンポジウム
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] 抗がん剤抵抗性を示す休止型がん幹細胞の解析と治療戦略2021
- Author(s)
  岡本康司
- Organizer
  第80回日本癌学会国際シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] シングルセル解析と空間的トランスクリプトームの統合によるがん組織多様性及び治療抵抗性の理解2021
- Author(s)
  岡本康司
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] 臨床がん由来のスフェロイドバネル構築と肺がん研究への応用2021
- Author(s)
  岡本康司
- Organizer
  第62 回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03081
[Presentation] 大腸がん幹細胞性の進展メカニズム2017
- Author(s)
  岡本康司
- Organizer
  第48回高松宮妃癌研究基金国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01581
[Presentation] シングルセル発現解析による大腸がん組織多様性の理解2017
- Author(s)
  岡本康司
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01581
[Presentation] スフェロイド形成による難治がん由来がん幹細胞の培養と特性解析2016
- Author(s)
  岡本康司
- Organizer
  第39 回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26293073
[Presentation] スフェロイド形成による難治がん由来がん幹細胞の培養と特性解析2016
- Author(s)
  岡本康司
- Organizer
  第39 回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01581
[Presentation] スフェロイド形成による難治がん由来がん幹細胞の培養と特性解析2016
- Author(s)
  岡本康司
- Organizer
  第39 回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K14390
[Presentation] ヒト大腸がん幹細胞の転移能制御機構の解析2015
- Author(s)
  岡本康司
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2015-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-15K14390
[Presentation] 単一細胞レベルの遺伝子発現解析により示されたLgr5 陽性大腸がん幹細胞の多様性2015
- Author(s)
  塩川大介、大畑広和、岡本康司
- Organizer
  第７４回日本癌学会年会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26293073
[Presentation] 単一細胞レベルの遺伝子発現解析による大腸がんの造腫瘍性細胞及び治療抵抗性細胞の同定2015
- Author(s)
  岡本康司
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K14390
[Presentation] 単一細胞レベルの遺伝子発現解析により示されたLgr5 陽性大腸がん幹細胞の多様性2015
- Author(s)
  塩川大介、大畑広和、岡本康司
- Organizer
  第７４回日本癌学会年会
- Place of Presentation
  横浜パシフィコ
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K14390
[Presentation] ヒト大腸がん幹細胞の転移能制御機構の解析2015
- Author(s)
  岡本康司
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2015-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-26293073
[Presentation] 単一細胞レベルの遺伝子発現解析による大腸がんの造腫瘍性細胞及び治療抵抗性細胞の同定2015
- Author(s)
  岡本康司
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26293073
[Presentation] 機能的スクリーニングによる大腸がん肝転移制御因子の同定2012
- Author(s)
  岡本　康司
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23112523
[Presentation] 機能的スクリーニングによる大腸がん肝転移制御因子の同定2012
- Author(s)
  岡本　康司
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] 機能的スクリーニングによる大腸がん肝転移制御因子の同定2012
- Author(s)
  岡本康司
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] マウスモデルにおける蛍光イメージングを用いた大腸がん転移制御因子の機能スクリーニング系の確立2012
- Author(s)
  岡本康司
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] miR-493による大腸がん転移の抑制機構2012
- Author(s)
  岡本　康司
- Organizer
  第２１回日本がん転移学会学術集会総会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] miR-493による大腸がん転移の抑制機構2012
- Author(s)
  岡本　康司
- Organizer
  第２１回日本がん転移学会学術集会総会
- Place of Presentation
  広島市
- Year and Date
  2012-07-12
- Data Source
  KAKENHI-PUBLICLY-23112523
[Presentation] miR-493による大腸がん転移の抑制機構2012
- Author(s)
  岡本康司
- Organizer
  第21回日本がん転移学会学術集会総会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] マウスモデルにおける蛍光イメージングを用いた大腸がん転移制御因子の機能スクリーニング系の確立2012
- Author(s)
  岡本　康司
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23112523
[Presentation] 大腸がん転移を抑制する新規マイクロRNAの同定及び解析2011
- Author(s)
  岡本康司
- Organizer
  第26回発癌病理研究会
- Place of Presentation
  ルネッサンスサッポロホテル(札幌市)
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] 大腸がん転移を抑制する新規マイクロRNAの同定及び解析2011
- Author(s)
  岡本康司
- Organizer
  第26回発癌病理研究会
- Place of Presentation
  ルネッサンスサッポロホテル(札幌市)
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PUBLICLY-23112523
[Presentation] 大腸がん転移の抑制に働くマイクロRNA及びshRNAの機能的スクリーニング2011
- Author(s)
  岡本康司
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] 大腸がん転移の抑制に働くマイクロRNA及びshRNAの機能的スクリーニング2011
- Author(s)
  岡本康司
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PUBLICLY-23112523
[Presentation] 大腸がん転移を抑制する新規因子の同定及び解析2010
- Author(s)
  岡本康司
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] 大腸がん転移の抑制に働くマイクロRNA及びshRNAの機能的スクリーニング2010
- Author(s)
  岡本康司
- Organizer
  第19回日本がん転移学会学術集会総会
- Place of Presentation
  金沢ニューグランドホテル(金沢市、石川県)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22590299
[Presentation] BHBN誘発マウス浸潤性膀胱がんにおけるゲノムDNAコピー数の変化2008
- Author(s)
  金本一洋、岡本康司、福田博政、落合正子、杉村隆、中釜斉
- Organizer
  第23回発癌病理学会
- Place of Presentation
  三重・鳥羽市(鳥羽国際ホテル)
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] 細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞束する事により、その活性を抑制する2008
- Author(s)
  岡本康司
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市(神戸ポートアイランド)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] 神経芽細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞質に拘束する事により、その活性を抑制する2008
- Author(s)
  岡本康司、中釜斉、田矢洋一
- Organizer
  第31回日本分子生物学会年会、第31回日本生化学会大会合同大会
- Place of Presentation
  神戸市(神戸ポートアイランド)
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] 神経芽細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞質に拘束する事により、その活性を抑制する2008
- Author(s)
  岡本康司
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市(名古屋国際会議場)
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] 神経芽細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞質に拘束する事により、その活性を抑制する2008
- Author(s)
  岡本康司、中釜斉、田矢洋一
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市(名古屋国際会議場)
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] Mdmx stimulates Mdm2-dependent ubiquitination and nuclear export of p532007
- Author(s)
  岡本康司、田矢洋一
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市(バシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] Mdmx癌遺伝子はMdm2ユビキチンリガーゼの活性化を介してp53を抑制する2007
- Author(s)
  大坪千裕、田矢洋一、岡本康司
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市(バシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] Mdmx/Mdm2癌遺伝子産物によるユビキチン化制御機構の破綻とその病理学的役割2007
- Author(s)
  岡本康司、大坪千裕、Christian Gaiddon、田矢洋一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会ワークショップ"シヌクレイノパチーと癌の統合的戦略"
- Place of Presentation
  横浜市(バシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-19590295
[Presentation] 単一細胞レベルの発現解析による難治性固形がんの発がんメカニズムの解析
- Author(s)
  岡本康司
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26293073
[Presentation] 肝転移巣由来の大腸がん幹細胞に特徴的な代謝プロファイルの検索
- Author(s)
  岡本康司
- Organizer
  第22 回がん代謝研究会
- Place of Presentation
  東京理科大学葛飾キャンパス講堂
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26293073
[Presentation] NADPH oxidaseの産生するROSはがん幹細胞の維持に広範な役割を果たす
- Author(s)
  岡本康司
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293073
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1. Gotoh Noriko (10251448)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 鈴木穣 (40323646)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 東條有伸 (00211681)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 島村徹平 (00623943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KONDOH Hiroshi (80402890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YOKODE Masayuki (20252447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SOGA Tomoyoshi (60338217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAORI Akifumi (20324626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANAKA Tomoaki (50447299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAGAMA Hitoshi (30198030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KATO Mamoru (40391916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Ishikawa Fuyuki (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 多田敬一郎 (80271568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 若林雄一 (40303119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 廣瀬遥香 (90764754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉原弘祐 (40547535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 加藤友康 (50224522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 榎本隆之 (90283754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 中戸隆一郎 (60583044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 塩川大介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKAMOTO Koji 岡本 康司

岡本 康司 オカモト コウジ

Research Projects

Research Products

Co-Researchers

Single-cell level integrated elucidation of genomic gene mutation heterogeneity and stem cell hierarchy in breast cancer primary and metastasis

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Integrated Elucidation of Genome Mutation Heterogeneity and Stem Cell Hierarchy in Breast Cancer at the Single-Cell Level

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Elucidation of chemoresistant network of clear cell ovarian cancer via spatial analysesPrincipal Investigator

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Anti-cancer therapies aiming for cure through inhibiting tumor-specific responses to environmental fluctuation

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Integrative analysis of genetical mutations and heterogeneity based on stemness in breast cancer cells

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個体モデルを用いた大規模シングルセル解析によるがん組織の要素還元論的な理解Principal Investigator

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Regulation epithelial stem cells by reactive oxgens species during oncogenic transformationPrincipal Investigator

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Elucidation of breast cancer tissue diversity by integration analysis of minimum unit omics

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Elucidation of chemoresistance of refracory cancer by single-cell gene expression analysesPrincipal Investigator

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がん転移制御因子の同定と解析を通じた臓器特異的な転移機構の解明Principal Investigator

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Senescence-inducing stress modulates glycolysis and the Warburg effect

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Regulation of cancer stem cells by MDMX/MDM2 oncoproteinsPrincipal Investigator

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Regulation of MDMX oncoprotein by genomic stressesPrincipal Investigator

Principal Investigator

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OKAMOTO Koji 岡本康司

岡本康司オカモトコウジ