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OKAMOTO Koji  岡本 康司

ORCIDConnect your ORCID iD *help
… Alternative Names

岡本 康司  オカモト コウジ

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Researcher Number 80342913
Other IDs
External Links
Affiliation (Current) 2020: 国立研究開発法人国立がん研究センター, 研究所, 分野長
Affiliation (based on the past Project Information) *help 2015 – 2020: 国立研究開発法人国立がん研究センター, 研究所, 分野長
2016: 国立研究開発法人国立がん研究センター, その他部局等, その他
2015: 国立研究開発法人国立がん研究センター, 研究所及び東病院臨床開発センター, 分野長
2014: 独立行政法人国立がん研究センター, 研究所, 分野長
2013: 国立がん研究センター研究所, 室長 … More
2010 – 2012: 独立行政法人国立がん研究センター, 研究所, 分野長
2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 早期がん研究プロジェクト, 室長
2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所及び東病院臨床開発センター・早期がん研究プロジェクト, 室長
2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 放射線研究部, 室長
2003: 国立がんセンター研究所, 放射線研究部, 室長 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Pathological medical chemistry / General medical chemistry / Tumor biology / Complex systems
Except Principal Investigator
General internal medicine (including Psychosomatic medicine) / Tumor biology / Basic Section 50010:Tumor biology-related / Broad Section I
Keywords
Principal Investigator
癌 / p53 / 発癌 / MDM2 / リン酸化 / 分子生物学 / シグナル伝達 / Mdmx / Mdm2 / cancer … More / neuroblastoma / neuron / がん幹細胞 / かん幹細胞 / がん転移 / 転移 / 分子腫瘍学 / 幹細胞 / シングルセル解析 … More
Except Principal Investigator
がん幹細胞 / 乳がん / 1細胞 / 遺伝子発現 / 老化 / 老年医学 / 解糖系代謝 / 癌化 / ストレス老化 / 発癌 / Single cell / cancer stem cells / breast cancer, / semaphoring, neuropilin / RNAシークエンス / シングルセル / 幹細胞 / スフェロイド培養 / neuropilin / PDXモデル / ゲノム変異 / 1細胞 / PDX / スフェロイド / トリプルネガティブ乳がん / IGF / セマフォリン / ニューロピリン / ストレス応答 / 蛋白質翻訳 / 発がん実験 / 抗腫瘍薬 Less
  • Research Projects

    (11 results)
  • Research Products

    (65 results)
  • Co-Researchers

    (42 People)
  •  Anti-cancer therapies aiming for cure through inhibiting tumor-specific responses to environmental fluctuationOngoing

    • Principal Investigator
      石川 冬木
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      Kyoto University
  •  Integrative analysis of genetical mutations and heterogeneity based on stemness in breast cancer cellsOngoing

    • Principal Investigator
      後藤 典子
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kanazawa University
  •  個体モデルを用いた大規模シングルセル解析によるがん組織の要素還元論的な理解Principal Investigator

    • Principal Investigator
      岡本 康司
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      National Cancer Center Japan
  •  Regulation epithelial stem cells by reactive oxgens species during oncogenic transformationPrincipal Investigator

    • Principal Investigator
      Okamoto Koji
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      National Cancer Center Japan
  •  Elucidation of breast cancer tissue diversity by integration analysis of minimum unit omics

    • Principal Investigator
      Gotoh Noriko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Kanazawa University
  •  Elucidation of chemoresistance of refracory cancer by single-cell gene expression analysesPrincipal Investigator

    • Principal Investigator
      Okamoto Koji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Cancer Center Japan
  •  がん転移制御因子の同定と解析を通じた臓器特異的な転移機構の解明Principal Investigator

    • Principal Investigator
      岡本 康司
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Japan
  •  Senescence-inducing stress modulates glycolysis and the Warburg effect

    • Principal Investigator
      KONDOH Hiroshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kyoto University
  •  Regulation of cancer stem cells by MDMX/MDM2 oncoproteinsPrincipal Investigator

    • Principal Investigator
      OKAMOTO Koji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Regulation of MDMX oncoprotein by genomic stressesPrincipal Investigator

    • Principal Investigator
      OKAMOTO Koji
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Mdm2癌遺伝子産物による、p53癌抑制蛋白の制御機構Principal Investigator

    • Principal Investigator
      岡本 康司
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2019 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells.2019

    • Author(s)
      Tominaga, K., Ninato, H., Murayama, T., Sasahara, A., Nishimura, T., Kiyokawa, E., Kanauchi, H., Shimizu, S., Sato, A., Nishioka, K., Tsuji, E., Yano, M., Ogawa, T., Ishii, H., Mori, M., Akashi, K., Okamoto, K., Tanabe, M., Tada, K., Tojo, A., Gotoh, N.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 116 Issue: 2 Pages: 625-630

    • DOI

      10.1073/pnas.1806851116

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-16J40231, KAKENHI-PROJECT-17K19587, KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279
  • [Journal Article] Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications2017

    • Author(s)
      Ishiguro T, Ohata H, Sato A, Yamawaki K, Enomoto T, Okamoto K.
    • Journal Title

      Cancer Sci

      Volume: 108 Pages: 283-289

    • DOI

      10.1111/cas.13155

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01581, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-17K16878, KAKENHI-PROJECT-17H04336, KAKENHI-PROJECT-16K15436, KAKENHI-PROJECT-15K20132
  • [Journal Article] 卵巣がん幹細胞の鍵シグナル2017

    • Author(s)
      岡本康司
    • Journal Title

      月刊「細胞」

      Volume: 49 Pages: 108-111

    • Data Source
      KAKENHI-PROJECT-26293073
  • [Journal Article] Heterogeneity among Lgr5-positive colon stem cells.2017

    • Author(s)
      Shiokawa D and Okamoto K
    • Journal Title

      Mol. Cell. Oncol.

      Volume: 16

    • DOI

      10.1080/23723556.2017.1335271

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01581
  • [Journal Article] The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells2017

    • Author(s)
      Shiokawa D, Sato A, Ohata H, Muto M, Sekine S, Kato M, Shibata T, Nakagama H, Okamoto K.
    • Journal Title

      Cell Reports

      Volume: 19 Pages: 981-994

    • DOI

      10.1016/j.celrep.2017.04.017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16878, KAKENHI-PUBLICLY-16H01581, KAKENHI-PROJECT-16K15436
  • [Journal Article] 卵巣がん幹細胞の鍵シグナル2017

    • Author(s)
      岡本康司
    • Journal Title

      月刊「細胞」

      Volume: 49 Pages: 108-111

    • Data Source
      KAKENHI-PUBLICLY-16H01581
  • [Journal Article] Sox2-dependent inhibition of p21 is associated with poor prognosis of endometrial cancer2017

    • Author(s)
      Yamawaki K, Ishiguro T, Mori Y, Yoshihara K, Suda K, Tamura R, Yamaguchi M, Sekine M, Kashima K, Higuchi M, Fujii M, Okamoto K, Enomoto T
    • Journal Title

      Cancer Science

      Volume: 108 Pages: 632-640

    • DOI

      10.1111/cas.13196

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01581, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-16K15502, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-17H04336, KAKENHI-PROJECT-16H06267, KAKENHI-PROJECT-15K09469, KAKENHI-PROJECT-15K10707, KAKENHI-PROJECT-15K20132
  • [Journal Article] 卵巣がん幹細胞の鍵シグナル2017

    • Author(s)
      岡本康司
    • Journal Title

      月刊「細胞」

      Volume: 49 Pages: 108-111

    • Data Source
      KAKENHI-PROJECT-15K14390
  • [Journal Article] Establishment and Characterization of an In Vitro Model of Ovarian Cancer Stem-like Cells with an Enhanced Proliferative Capacity.2016

    • Author(s)
      Ishiguro T, Sato A, Ohata H, Ikarashi Y, Takahashi R, Ochiya T, Yoshida M, Tsuda H, Onda T, Kato T, Kasamatsu T, Enomoto T, Tanaka K, Nakagama H, Okamoto K.
    • Journal Title

      Cancer Res.

      Volume: 76 Pages: 150-160

    • DOI

      10.1158/0008-5472.can-15-0361

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-26870877, KAKENHI-PROJECT-25293338, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-15K15598
  • [Journal Article] TNIK Inhibition Abrogates Colorectal Cancer Stemness.2016

    • Author(s)
      Masuda M, Uno Y, Ohbayashi N, Ohata H, Mimata A, Kukimoto-Niino M, Moriyama H, Kashimoto S, Inoue T, Goto N, Okamoto K, Shirouzu M, Sawa M, Yamada T.
    • Journal Title

      Nature Commun.

      Volume: - Pages: 12586-12586

    • DOI

      10.1038/ncomms12586

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01581, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-16K14627
  • [Journal Article] MicroRNA-574-3p, identified by microRNA library-based functional screening, modulates tamoxifen response in breast cancer.2015

    • Author(s)
      Ujihira T, Ikeda K, Suzuki T, Yamaga R, Sato W, Horie-Inoue K, Shigekawa T, Osaki A, Saeki T, Okamoto K, Takeda S, Inoue S
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 7641-7641

    • DOI

      10.1038/srep07641

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-26293223
  • [Journal Article] Hepatocyte nuclear factor-1β promotes glucose uptake and glycolytic activity in ovarian clear carcinoma.2015

    • Author(s)
      T Okamoto, M Mandai, N Matsumura, K Yamaguchi, H Kondoh, Y Amano, T Baba, J Hamanishi, K Abiko, K Kosaka, S K, Murphy, S Mori, I Konishi
    • Journal Title

      Mol Carcinog.

      Volume: - Pages: 1-15

    • DOI

      10.1002/mc.22072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390186, KAKENHI-PROJECT-24791700, KAKENHI-PROJECT-24791701, KAKENHI-PROJECT-25670350, KAKENHI-PROJECT-25670703, KAKENHI-PROJECT-26253080
  • [Journal Article] MicroRNA library-based functional screening identified androgen-sensitive miR-216a as a player in bicalutamide resistance in prostate cancer.2015

    • Author(s)
      Miyazaki T, Ikeda K, Horie-Inoue K, Okamoto K, Inoue S
    • Journal Title

      J Clin Med.

      Volume: 4 Pages: 1853-1865

    • DOI

      10.3390/jcm4101853

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-15K15073, KAKENHI-PROJECT-15K15353, KAKENHI-PROJECT-26861292, KAKENHI-PROJECT-26293073
  • [Journal Article] Senescence-inducing stress promotes proteolysis of glycolytic enzyme phosphoglycerate mutase via ubiquitin ligase Mdm2.2014

    • Author(s)
      T Mikawa, T Maruyama, K Okamoto, H Nakagama, ME LLeonart, T Tsusaka, K Hori, I Murakami, T Izumi, A T-Kondo, M Yokode, G Peters, D Beach, & H Kondoh
    • Journal Title

      Journal of Cell Biology

      Volume: 204(5) Pages: 729-45

    • DOI

      10.1083/jcb.201306149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390186, KAKENHI-PLANNED-24115004, KAKENHI-PROJECT-25670350
  • [Journal Article] MKK7 mediates miR-493-dependent suppression of liver metastasis of colon cancer cells.2014

    • Author(s)
      Sakai H, Sato A, Aihara Y, Ikarashi Y, Midorikawa Y, Nakagama H, Okamoto K.
    • Journal Title

      Cancer Sci.

      Volume: 105 Pages: 425-430

    • DOI

      10.1111/cas.12380

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23591972, KAKENHI-PROJECT-26293073
  • [Journal Article] Short Hairpin RNA Library-Based Functional Screening Identified Ribosomal Protein L31 That Modulates Prostate Cancer Cell Growth via p53 Pathway.2014

    • Author(s)
      Maruyama Y, Miyazaki T, Ikeda K, Okumura T, Sato W, Horie-Inoue K, Okamoto K, Takeda S, Inoue S
    • Journal Title

      PLoS One

      Volume: 9 Pages: 828-833

    • DOI

      10.1371/journal.pone.0108743

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-26293073
  • [Journal Article] miR-493 induction during carcinogenesis blocks metastatic settle merit of colon cancer cells in liver2012

    • Author(s)
      Okamoto K., et al
    • Journal Title

      EMBO Journal

      Volume: 31 Pages: 1752-1763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Journal Article] Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance ofcolon cancer-initiating cells2012

    • Author(s)
      H. Ohata, T. Ishiguro, Y. Aihara, A. Sato, H. Sakai, S. Sekine, H. Taniguchi, T. Akasu, S. Fujita, H. Nakagama, K. Okamoto
    • Journal Title

      Cancer Res

      Volume: 72 Pages: 5101-5110

    • Data Source
      KAKENHI-PROJECT-22590299
  • [Journal Article] miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver.2012

    • Author(s)
      Koji Okamoto
    • Journal Title

      EMBO J

      Volume: 31 Pages: 1752-1763

    • DOI

      10.1038/emboj.2012.25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590299, KAKENHI-PROJECT-23300359, KAKENHI-PUBLICLY-23112523
  • [Journal Article] Differential expression of nanogl and nanogp8 in colon cancer cells2012

    • Author(s)
      T. Ishiguro, A. Sato, H. Ohata, H. Sakai, H. Nakagama, K. Okamoto:
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 418 Pages: 199-204

    • Data Source
      KAKENHI-PROJECT-22590299
  • [Journal Article] miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver2012

    • Author(s)
      K. Okamoto, T. Ishiguro, Y. Midorikawa, H. Ohata, M. Izumiya, N. Tsuchiya, A. Sato, H. Sakai, H. Nakagama
    • Journal Title

      EMBO J

      Volume: 31 Pages: 1752-1763

    • Data Source
      KAKENHI-PROJECT-22590299
  • [Journal Article] miR-493 induction during carcinogenesis blocks metastatic settlemerit of colon cancer cells in liver2012

    • Author(s)
      Okamoto K., et al
    • Journal Title

      EMBO Journal

      Volume: 31 Pages: 1752-1763

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23112523
  • [Journal Article] Tumor-suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p212011

    • Author(s)
      N. Tsuchiya, M. Izumiya, H. Ogata-Kawata, K. Okamoto, Y. Fu j iwara, M. Nakai, A. Okabe, A. J. Schetter, E. D. Bowman, Y. Midorikawa, Y. Sugiyama, H. Aburatani, C. C. Harris, H. Nakagama
    • Journal Title

      Cancer Res

      Volume: 71 Pages: 4628-4639

    • Data Source
      KAKENHI-PROJECT-22590299
  • [Journal Article] Systematic exploration of cancer-associated microRNA through functional screening assays2011

    • Author(s)
      M. Izumiya, N. Tsuchiya, K. Okamoto, H. Nakagama
    • Journal Title

      Cancer Sci

      Volume: 102 Pages: 1615-21

    • NAID

      10030242740

    • Data Source
      KAKENHI-PROJECT-22590299
  • [Journal Article] Cytoplasmic Tethering is involved in Synergistic Inhibition of p53 by Mdmx and Mdm2.2009

    • Author(s)
      C. Ohtsubo, D. Shiokawa, M. Kodama, C. Gaiddon, H. Nakagama, A. G. Jochemsen, Y. Taya, and K. Okamoto
    • Journal Title

      Cancer Science

      Pages: 0-0

    • NAID

      10027192333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Journal Article] Frequent inactivation of A20 in B-cell lymphomas.2009

    • Author(s)
      M. Kato (the names of 21 authors omitted) K. Okamoto, K. Tobinai, H. Nakagama, T. Nakahata, T. Yoshino, Y. Kobayashi, and S. Ogawa
    • Journal Title

      Nature in press

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Journal Article] Lysine-independent turnover of cyclin G1 can be stabilized by B'alpha subunits of protein phosphatase 2A.2009

    • Author(s)
      H. Li, K. Okamoto, M. J. Peart, and C. Prives
    • Journal Title

      Mol. Cell Biol. 29

      Pages: 919-928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Journal Article] Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.2008

    • Author(s)
      Y. Abe, E. Oda-Sato, K. Tobiume, K. Kawaguchi, Y. Taya, K. Okamoto, M. Oren, and N. Tanaka
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages: 4838-4843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Journal Article] Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis.2007

    • Author(s)
      S. Benosman, I. Gross, N. Clarke, A. G. Jochemsen, K. Okamoto, J. P. Loeffler, and C. Gaiddon
    • Journal Title

      Cell Death & Differentiation 14

      Pages: 2047-2057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] 大腸がん幹細胞性の進展メカニズム2017

    • Author(s)
      岡本康司
    • Organizer
      第48回高松宮妃癌研究基金国際シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01581
  • [Presentation] シングルセル発現解析による大腸がん組織多様性の理解2017

    • Author(s)
      岡本康司
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01581
  • [Presentation] スフェロイド形成による難治がん由来がん幹細胞の培養と特性解析2016

    • Author(s)
      岡本康司
    • Organizer
      第39 回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-11-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14390
  • [Presentation] スフェロイド形成による難治がん由来がん幹細胞の培養と特性解析2016

    • Author(s)
      岡本康司
    • Organizer
      第39 回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293073
  • [Presentation] スフェロイド形成による難治がん由来がん幹細胞の培養と特性解析2016

    • Author(s)
      岡本康司
    • Organizer
      第39 回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01581
  • [Presentation] 単一細胞レベルの遺伝子発現解析による大腸がんの造腫瘍性細胞及び治療抵抗性細胞の同定2015

    • Author(s)
      岡本康司
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14390
  • [Presentation] 単一細胞レベルの遺伝子発現解析による大腸がんの造腫瘍性細胞及び治療抵抗性細胞の同定2015

    • Author(s)
      岡本康司
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293073
  • [Presentation] 単一細胞レベルの遺伝子発現解析により示されたLgr5 陽性大腸がん幹細胞の多様性2015

    • Author(s)
      塩川大介、大畑広和、岡本康司
    • Organizer
      第74回日本癌学会年会
    • Place of Presentation
      横浜パシフィコ
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293073
  • [Presentation] ヒト大腸がん幹細胞の転移能制御機構の解析2015

    • Author(s)
      岡本康司
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      石川県立音楽堂交流ホール
    • Year and Date
      2015-07-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293073
  • [Presentation] ヒト大腸がん幹細胞の転移能制御機構の解析2015

    • Author(s)
      岡本康司
    • Organizer
      第3回がんと代謝研究会
    • Place of Presentation
      石川県立音楽堂交流ホール
    • Year and Date
      2015-07-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14390
  • [Presentation] 単一細胞レベルの遺伝子発現解析により示されたLgr5 陽性大腸がん幹細胞の多様性2015

    • Author(s)
      塩川大介、大畑広和、岡本康司
    • Organizer
      第74回日本癌学会年会
    • Place of Presentation
      横浜パシフィコ
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K14390
  • [Presentation] miR-493による大腸がん転移の抑制機構2012

    • Author(s)
      岡本 康司
    • Organizer
      第21回日本がん転移学会学術集会総会
    • Place of Presentation
      広島市
    • Year and Date
      2012-07-12
    • Data Source
      KAKENHI-PUBLICLY-23112523
  • [Presentation] miR-493による大腸がん転移の抑制機構2012

    • Author(s)
      岡本康司
    • Organizer
      第21回日本がん転移学会学術集会総会
    • Place of Presentation
      広島市
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] マウスモデルにおける蛍光イメージングを用いた大腸がん転移制御因子の機能スクリーニング系の確立2012

    • Author(s)
      岡本康司
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] マウスモデルにおける蛍光イメージングを用いた大腸がん転移制御因子の機能スクリーニング系の確立2012

    • Author(s)
      岡本 康司
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PUBLICLY-23112523
  • [Presentation] 機能的スクリーニングによる大腸がん肝転移制御因子の同定2012

    • Author(s)
      岡本 康司
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PUBLICLY-23112523
  • [Presentation] 機能的スクリーニングによる大腸がん肝転移制御因子の同定2012

    • Author(s)
      岡本 康司
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] miR-493による大腸がん転移の抑制機構2012

    • Author(s)
      岡本 康司
    • Organizer
      第21回日本がん転移学会学術集会総会
    • Place of Presentation
      広島市
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] 機能的スクリーニングによる大腸がん肝転移制御因子の同定2012

    • Author(s)
      岡本康司
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] 大腸がん転移を抑制する新規マイクロRNAの同定及び解析2011

    • Author(s)
      岡本康司
    • Organizer
      第26回発癌病理研究会
    • Place of Presentation
      ルネッサンスサッポロホテル(札幌市)
    • Year and Date
      2011-08-30
    • Data Source
      KAKENHI-PUBLICLY-23112523
  • [Presentation] 大腸がん転移の抑制に働くマイクロRNA及びshRNAの機能的スクリーニング2011

    • Author(s)
      岡本康司
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PUBLICLY-23112523
  • [Presentation] 大腸がん転移の抑制に働くマイクロRNA及びshRNAの機能的スクリーニング2011

    • Author(s)
      岡本康司
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] 大腸がん転移を抑制する新規マイクロRNAの同定及び解析2011

    • Author(s)
      岡本康司
    • Organizer
      第26回発癌病理研究会
    • Place of Presentation
      ルネッサンスサッポロホテル(札幌市)
    • Year and Date
      2011-08-30
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] 大腸がん転移を抑制する新規因子の同定及び解析2010

    • Author(s)
      岡本康司
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] 大腸がん転移の抑制に働くマイクロRNA及びshRNAの機能的スクリーニング2010

    • Author(s)
      岡本康司
    • Organizer
      第19回日本がん転移学会学術集会総会
    • Place of Presentation
      金沢ニューグランドホテル(金沢市、石川県)
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-22590299
  • [Presentation] 細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞束する事により、その活性を抑制する2008

    • Author(s)
      岡本康司
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸市(神戸ポートアイランド)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] 神経芽細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞質に拘束する事により、その活性を抑制する2008

    • Author(s)
      岡本康司、中釜斉、田矢洋一
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市(名古屋国際会議場)
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] BHBN誘発マウス浸潤性膀胱がんにおけるゲノムDNAコピー数の変化2008

    • Author(s)
      金本一洋、岡本康司、福田博政、落合正子、杉村隆、中釜斉
    • Organizer
      第23回発癌病理学会
    • Place of Presentation
      三重・鳥羽市(鳥羽国際ホテル)
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] 神経芽細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞質に拘束する事により、その活性を抑制する2008

    • Author(s)
      岡本康司、中釜斉、田矢洋一
    • Organizer
      第31回日本分子生物学会年会、第31回日本生化学会大会合同大会
    • Place of Presentation
      神戸市(神戸ポートアイランド)
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] 神経芽細胞腫において、Mdmx及びMdm2癌遺伝子産物は協調してp53を細胞質に拘束する事により、その活性を抑制する2008

    • Author(s)
      岡本康司
    • Organizer
      第67回 日本癌学会学術総会
    • Place of Presentation
      名古屋市(名古屋国際会議場)
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] Mdmx癌遺伝子はMdm2ユビキチンリガーゼの活性化を介してp53を抑制する2007

    • Author(s)
      大坪千裕、田矢洋一、岡本康司
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜市(バシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] Mdmx stimulates Mdm2-dependent ubiquitination and nuclear export of p532007

    • Author(s)
      岡本康司、田矢洋一
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜市(バシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] Mdmx/Mdm2癌遺伝子産物によるユビキチン化制御機構の破綻とその病理学的役割2007

    • Author(s)
      岡本康司、大坪千裕、Christian Gaiddon、田矢洋一
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会ワークショップ"シヌクレイノパチーと癌の統合的戦略"
    • Place of Presentation
      横浜市(バシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-19590295
  • [Presentation] NADPH oxidaseの産生するROSはがん幹細胞の維持に広範な役割を果たす

    • Author(s)
      岡本 康司
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26293073
  • [Presentation] 肝転移巣由来の大腸がん幹細胞に特徴的な代謝プロファイルの検索

    • Author(s)
      岡本 康司
    • Organizer
      第22 回がん代謝研究会
    • Place of Presentation
      東京理科大学 葛飾キャンパス講堂
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-26293073
  • [Presentation] 単一細胞レベルの発現解析による難治性固形がんの発がんメカニズムの解析

    • Author(s)
      岡本 康司
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293073
  • 1.  Gotoh Noriko (10251448)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  東條 有伸 (00211681)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  島村 徹平 (00623943)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KONDOH Hiroshi (80402890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  YOKODE Masayuki (20252447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  SOGA Tomoyoshi (60338217)
    # of Collaborated Projects: 1 results
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  • 7.  TAKAORI Akifumi (20324626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  TANAKA Tomoaki (50447299)
    # of Collaborated Projects: 1 results
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  • 9.  NAKAGAMA Hitoshi (30198030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  KATO Mamoru (40391916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  鈴木 穣 (40323646)
    # of Collaborated Projects: 1 results
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  • 12.  多田 敬一郎 (80271568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  石川 冬木 (30184493)
    # of Collaborated Projects: 1 results
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  • 14.  若林 雄一 (40303119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  HIDESHI Ishii
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  MORI masaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  HAMANISHI Jyunzo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  MATSUMURA Noriomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  BABA Tsukasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  MASUDA Mari
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  Hara Toshifumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  Higuchi Masaya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 23.  YOSHIHARA Kousuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  MIDORIKAWA Yutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  高橋 陵宇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  榎本 隆之
    # of Collaborated Projects: 0 results
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  • 27.  仲 哲治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  石黒 竜也
    # of Collaborated Projects: 0 results
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  • 29.  大畑 広和
    # of Collaborated Projects: 0 results
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  • 30.  井上 聰
    # of Collaborated Projects: 0 results
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  • 31.  堀江 公仁子
    # of Collaborated Projects: 0 results
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  • 32.  山口 建
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  万代 昌紀
    # of Collaborated Projects: 0 results
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  • 34.  岡本 愛光
    # of Collaborated Projects: 0 results
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  • 35.  小西 郁生
    # of Collaborated Projects: 0 results
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  • 36.  森 誠一
    # of Collaborated Projects: 0 results
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  • 37.  安彦 郁
    # of Collaborated Projects: 0 results
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  • 38.  池田 和博
    # of Collaborated Projects: 0 results
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  • 39.  宮崎 利明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  藤井 雅寛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  関根 正幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  山口 雅幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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