KAMINUMA Osamu 神沼修

… Alternative Names

神沼修カミヌマオサム

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Researcher Number	80342921
Other IDs	https://orcid.org/0000-0003-1211-0410
Affiliation (Current)	2025: 広島大学, 原爆放射線医科学研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 広島大学, 原爆放射線医科学研究所, 教授 2020: 山梨大学, 大学院総合研究部, 准教授 2017 – 2018: 山梨大学, 大学院総合研究部, 准教授 2016 – 2017: 山梨大学, 総合研究部, 准教授 2012 – 2016: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員 … More 2015: 公益財団法人東京都医学総合研究所, その他部局等, 研究員 2011: 財団法人東京都医学総合研究所, ゲノム医科学研究分野, 主任研究員 2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2009: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2004: 財団法人東京都医学研究機構, 研究員 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42040:Laboratory animal science-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Integrative animal science / Laboratory animal science / Biological pharmacy Except Principal Investigator Basic Section 56030:Urology-related / Basic Section 54020:Connective tissue disease and allergy-related / Laboratory medicine / Basic Section 59010:Rehabilitation science-related … More / Medium-sized Section 57:Oral science and related fields / Basic Section 56050:Otorhinolaryngology-related / Basic Section 42040:Laboratory animal science-related / Integrative animal science / Biological pharmacy / Biological Sciences Less
Keywords	Principal Investigator T細胞 / アレルギー / T細胞受容体 / 核移植 / 疾患モデル / ヒト化マウス / クローンマウス / マウス / 過敏性亢進 / クローン動物 … More / 実験動物学 / 発現調節 / 分子間結合 / 転写因子 / 免疫抑制薬 / 免疫学 … More Except Principal Investigator T細胞 / 炎症 / 気管支喘息 / アレルゲン免疫療法 / アレルギー性鼻炎 / スギ花粉症 / 舌下免疫療法 / 脳梗塞 / 転写因子 / ウイルス療法 / 膀胱癌 / 分岐鎖アミノ酸 / 薬剤抵抗性 / 上皮間葉系移行 / 腫瘍活性 / 酸化ストレス / 腎細胞癌 / メディエータ / 遅発型喘息反応 / T 細胞 / 免疫療法 / ヘルパーT細胞 / 歯周病 / 免疫応答 / 口腔感染症 / 花粉症 / 脱顆粒 / トロンボスポンジン1 / マスト細胞 / 喘息 / ステロイド抵抗性 / マウスの遺伝子背景 / ゲノム編集技術 / 抗核抗体価の上昇 / 結合配列 / miRNA / ゲノム編集 / 血清アミロイドP成分 / 炎症の系統差 / 自己免疫疾患 / 肥満と突然死 / 皮膚疾患 / 免疫反応の系統差 / アレルギー / 再生医学 / 生理学 / 獣医学 / Ano-1 / Cre/loxp / 消化管 / ジフテリア毒素 / ANO-1 / c-kit / TRECKマウス / カハール介在細胞 / ゲノムワイド解析 / 苦味受容体 / 統合解析 / バイオマーカー / 脳卒中 / 新規免疫抑制薬 / 免疫抑制薬 / CN / NFAT / サイトカイン / 免疫学 / 発生・分化 Less

Simultaneous cytokine triad-producing viral therapy for BCG-refractory bladder cancer
- Principal Investigator
  
  小畠浩平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Hiroshima University
核移植クローン技術に基づく免疫応答・疾患発症機構の包括的研究基盤Principal Investigator
- Principal Investigator
  
  神沼修
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Hiroshima University
Analysis of mediators involved in T cell dependent late asthmatic response
- Principal Investigator
  
  MORI AKIO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
Clarification of the mechanism of anti-PD-1 antibody resistance acquisition based on BACH1 functional analysis in renal cell carcinoma
- Principal Investigator
  
  Takemoto Kenshiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Hiroshima University
Influence of branched-chain amino acid on the outcome in the acute ischemic stroke patients
- Principal Investigator
  
  Naohisa Hosomi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Hiroshima University
Basic research for new immunological therapies based on a pathological mechanism of periodontal disease
- Principal Investigator
  
  Tanaka Yoshihiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Fukuoka Dental College
Mechanism of suppression of mast cell degranulation by sublingual immunotherapy
- Principal Investigator
  
  Gotoh Minoru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nippon Medical School
Usefulness of T cell cloned mice as bioresources for immunological sciencePrincipal Investigator
- Principal Investigator
  
  Kaminuma Osamu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Hiroshima University
Analysis of the mechanism of increase in antinuclear antibody levels due to differences in genetic background of mice
- Principal Investigator
  
  ITO Sadahiro
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Yamanashi
Investigation on steroid resistant airway inflammation
- Principal Investigator
  
  MORI AKIO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
Mechanisms underlying the development of hyperresponsiveness commonly induced by T cell subsets in allergic diseasesPrincipal Investigator
- Principal Investigator
  
  Kaminuma Osamu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Hiroshima University
  University of Yamanashi
Elucidation of regeneration mechanism of digestive tract pacemaker cell by modified TRECK method
- Principal Investigator
  
  Hori Masatoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokyo
Elucidation of immune function through antigen-specific monoclonal T cell receptorPrincipal Investigator
- Principal Investigator
  
  KAMINUMA Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  University of Yamanashi
  Tokyo Metropolitan Institute of Medical Science
Elucidation of mechanism on neuronal cell death and development of hemodiagnosis in ischemic stroke
- Principal Investigator
  
  Hosomi Naohisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Hiroshima University
Development of diagnostic method for efficacy of sublingual immunotherapy based on systematic genome wide analysis
- Principal Investigator
  
  Gotoh Minoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nippon Medical School
Development of inducible and constitutive neutrophil-deficient mice for analyzing allergic inflammationPrincipal Investigator
- Principal Investigator
  
  KAMINUMA Osamu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Development of a novel treatment for immunoregulation by analyzing specific regulatory mechanisms of the NFAT family.
- Principal Investigator
  
  KITAMURA Noriko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Specific regulation for NFAT based on diversity of the NFAT familyPrincipal Investigator
- Principal Investigator
  
  KAMINUMA Osamu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
転写因子による細胞系列の決定および維持の染色体制御機構
- Principal Investigator
  
  宮武昌一郎
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Journal Article] JPH203, a LAT1 inhibitor, alleviates steroid‐resistant murine airway inflammation mediated by Th17 cells2023
- Author(s)
  Hayashi Keitaro、Saeki Mayumi、Miura Kento、Yamasaki Norimasa、Matsuda Masaya、Shimora Hayato、Nabe Takeshi、Shimizu Yasuo、Fujita Tomoe、Endou Hitoshi、Kaminuma Osamu
- Journal Title
  
  Allergy
  
  Volume: 78 Issue: 10 Pages: 2780-2783
- DOI
  10.1111/all.15798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-22H00398
[Journal Article] Evolutionary mechanisms underlying the diversification of nuclear factor of activated T cells across vertebrates2023
- Author(s)
  Gamboa Maribet、Kitamura Noriko、Miura Kento、Noda Satoko、Kaminuma Osamu
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 6468-6468
- DOI
  10.1038/s41598-023-33751-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-22H00398
[Journal Article] Generation of reporter mice for detecting the transcriptional activity of nuclear factor of activated T cells2023
- Author(s)
  Yamasaki Norimasa、Miura Kento、Ogata Sawako、Miura Shuka、Uchimura Arikuni、Satoh Yasunari、Toshishige Masaaki、Hosomi Naohisa、Gamboa Maribet、Kitamura Noriko、Kaminuma Osamu
- Journal Title
  
  Exp. Anim.
  
  Volume: 72 Issue: 4 Pages: 454-459
- DOI
  10.1538/expanim.23-0043
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14117, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-22H00398
[Journal Article] Th17-dependent nasal hyperresponsiveness is mitigated by steroid treatment2022
- Author(s)
  Ueda, S., Miura, K., Kawasaki, H., Ogata, S., Yamasaki, N., Miura, S., Mori, A., and Kaminuma, O.
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 5 Pages: 674-674
- DOI
  10.3390/biom12050674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08486
[Journal Article] Expression and Function of Nicotinic Acetylcholine Receptors in Induced Regulatory T Cells.2022
- Author(s)
  Nakata Y, Miura K, Yamasaki N, Ogata S, Miura S, Hosomi N, Kaminuma O.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23 Issue: 3 Pages: 1779-1779
- DOI
  10.3390/ijms23031779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11214, KAKENHI-PROJECT-19K16017
[Journal Article] 重症喘息のステロイド抵抗性とその制御2022
- Author(s)
  森　晶夫、神山　智、大友　暁美、山口　美也子、組谷　智恵美、岩本　圭右、矢野　光一、藤田　教寛、岩田　真紀、永山　貴紗子、劉　楷、中村　祐人、濱田　祐斗、渡井　健太郎、上出　庸介、福冨　友馬、関谷　潔史、松本　幸一郎、谷本　安、小林　信之、大友　隆之、神沼　修
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 157 Pages: 293-298
- Data Source
  KAKENHI-PROJECT-21K08486
[Journal Article] Re-evaluation of over-the-counter histamine H1-receptor antagonists based on their effects on murine models of allergen-induced nasal hyperresponsiveness2022
- Author(s)
  Uda, N., Ogata, S., Yamasaki, N., Miura, S., Hosomi, N., Mori, A., Goto, M., Miura, K., and Kaminuma, O.
- Journal Title
  
  J. Pharm. Sciences.
  
  Volume: 150 Issue: 4 Pages: 275-278
- DOI
  10.1016/j.jphs.2022.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08486, KAKENHI-PROJECT-22H00398
[Journal Article] T細胞依存的アレルギー性炎症の臓器・サブセット特異的な薬剤応答性2021
- Author(s)
  神沼　修、三浦　健人、林　啓太朗、佐伯　真弓、廣井　隆親、森　晶夫
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41 Pages: 80-83
- Data Source
  KAKENHI-PROJECT-18K19561
[Journal Article] Progress of genome editing technology and developmental biology useful for radiation research2021
- Author(s)
  Miura Kento、Ogura Atsuo、Kobatake Kohei、Honda Hiroaki、Kaminuma Osamu
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 62 Issue: Supplement_1 Pages: i53-i63
- DOI
  10.1093/jrr/rraa127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19K16017
[Journal Article] Sublingual Immunotherapy: How Sublingual Allergen Administration Heals Allergic Diseases; Current Perspective about the Mode of Action2021
- Author(s)
  Gotoh Minoru、Kaminuma Osamu
- Journal Title
  
  Pathogens
  
  Volume: 10 Issue: 2 Pages: 147-147
- DOI
  10.3390/pathogens10020147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09901
[Journal Article] T細胞依存的アレルギー性炎症の臓器・サブセット特異的な薬剤応答性2021
- Author(s)
  神沼　修、三浦　健人、林　啓太朗、佐伯　真弓、廣井　隆親、森　晶夫
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41 Pages: 172-175
- Data Source
  KAKENHI-PROJECT-19H03145
[Journal Article] Suppressive effect of dexamethasone on murine Th9 cell-mediated nasal eosinophilic inflammation2021
- Author(s)
  Koyama Teidai、Miura Kento、Yamasaki Norimasa、Ogata Sawako、Ito Daiki、Saeki Mayumi、Hiroi Takachika、Mori Akio、Kaminuma Osamu
- Journal Title
  
  Asia Pacific Allergy
  
  Volume: 11 Issue: 3 Pages: e25-e25
- DOI
  10.5415/apallergy.2021.11.e25
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-21K08486, KAKENHI-PROJECT-19K16017
[Journal Article] L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation2021
- Author(s)
  Ito Daiki、Miura Kento、Saeki Mayumi、Yamasaki Norimasa、Ogata Sawako、Koyama Teidai、Hiroi Takachika、Mori Akio、Endou Hitoshi、Hayashi Keitaro、Kaminuma Osamu
- Journal Title
  
  Asia Pacific Allergy
  
  Volume: 11 Issue: 3 Pages: e33-e33
- DOI
  10.5415/apallergy.2021.11.e33
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K08486, KAKENHI-PROJECT-19K16017
[Journal Article] L-type amino acid transporter 1 (LAT1)-specific inhibitor is effective against T cell-mediated nasal hyperresponsiveness2020
- Author(s)
  Kaminuma Osamu、Nishimura Tomoe、Saeki Mayumi、Yamasaki Norimasa、Ogata Sawako、Fujita Tomoe、Endou Hitoshi、Hayashi Keitaro
- Journal Title
  
  Allergol. Int.
  
  Volume: 69 Issue: 3 Pages: 455-458
- DOI
  10.1016/j.alit.2019.12.006
- NAID
  130007877710
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-18K19561
[Journal Article] Identification of pyrogallol from Awa-tea as an anti-allergic compound that suppresses nasal symptoms and IL-9 gene expression2020
- Author(s)
  Nakano Tomohiro、Ikeda Mitsuhiro、Wakugawa Tomoharu、Kashiwada Yoshiki、Kaminuma Osamu、Kitamura Noriko、Yabumoto Masam、Fujino Hiromichi、Kitamura Yoshiaki、Fukui Hiroyuki、Takeda Noriaki、Mizuguchi Hiroyuki
- Journal Title
  
  J. Med. Invest.
  
  Volume: 67 Issue: 3.4 Pages: 289-297
- DOI
  10.2152/jmi.67.289
- NAID
  130007936857
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09693, KAKENHI-PROJECT-18K19561
[Journal Article] Epicutaneous allergen administration without antigen delivery device induces local T cell response and alleviates food allergic enteropathy2020
- Author(s)
  Morinaga Mamiko、Nakajima-Adachi Haruyo、Hiraide Erika、Kitamura Noriko、Kaminuma Osamu、Hiroi Takachika、Ohashi-Doi Katsuyo、Hachimura Satoshi
- Journal Title
  
  Allergology International
  
  Volume: 69 Issue: 4 Pages: 622-625
- DOI
  10.1016/j.alit.2020.04.010
- NAID
  130007926236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03145
[Journal Article] Association of Basophil-Expressing Genes with Effectiveness of Sublingual Immunotherapy2020
- Author(s)
  Gotoh Minoru、Kaminuma Osamu、Nakaya Akihiro、Saeki Mayumi、Nishimura Tomoe、Kitamura Noriko、Hiroi Takachika、Okubo Kimihiro
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 87 Issue: 1 Pages: 49-52
- DOI
  10.1272/jnms.JNMS.2020_87-104
- NAID
  130007807559
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2020-02-15
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06713, KAKENHI-PROJECT-19K09901
[Journal Article] 皮膚アレルギー研究に役立つ新しいマウスモデル2020
- Author(s)
  神沼　修、吉川　日出雄、森　晶夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 73 Pages: 506-512
- Data Source
  KAKENHI-PROJECT-19H03145
[Journal Article] マウスTh9 細胞移入喘息モデルの解析からみえてきた新たな気道過敏性亢進機構2020
- Author(s)
  佐伯　真弓、神沼　修、廣井　隆親
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 155 Pages: 375-380
- NAID
  130007933869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19561
[Journal Article] 特集Ⅱ　皮膚アレルギー研究最前線　皮膚アレルギー研究に役立つ新しいマウスモデル2020
- Author(s)
  神沼　修、吉川日出雄、森晶夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 73 Pages: 506-512
- Data Source
  KAKENHI-PROJECT-18K08422
[Journal Article] 皮膚アレルギー研究に役立つ新しいマウスモデル2020
- Author(s)
  神沼　修、吉川　日出雄、森　晶夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 73 Pages: 506-512
- Data Source
  KAKENHI-PROJECT-18K19561
[Journal Article] T Cell-Mediated Nasal Hyperresponsiveness in Allergic Rhinitis2020
- Author(s)
  Osamu Kaminuma, Tomoe Nishimura, Mayumi Saeki, Akio Mori, Takachika Hiroi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 1 Pages: 36-40
- DOI
  10.1248/bpb.b18-01021
- NAID
  130007779207
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19561, KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-18K08422
[Journal Article] Role of CD4+ T Cells in Allergic Airway Diseases: Learning from Murine Models2020
- Author(s)
  Miura Kento、Inoue Kimiko、Ogura Atsuo、Kaminuma Osamu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 20 Pages: 7480-7480
- DOI
  10.3390/ijms21207480
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16017, KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-18K19561
[Journal Article] Potential mechanisms of T cell-mediated and eosinophil-independent bronchial hyperresponsiveness.2019
- Author(s)
  Saeki M, Kaminuma O, Nishimura T, Kitamura N, Mori A, Hiroi T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 12 Pages: 2980-2981
- DOI
  10.3390/ijms20122980
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06713, KAKENHI-PROJECT-18K07190, KAKENHI-PROJECT-18K08422, KAKENHI-PROJECT-18K19561
[Journal Article] T Cell-Mediated Nasal Hyperresponsiveness in Allergic Rhinitis2019
- Author(s)
  Kaminuma, O., Nishimura, T., Saeki, M., Mori, A., and Hiroi, T.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 43 Pages: 36-40
- NAID
  130007779207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08422
[Journal Article] Thrombospondin 1-mediated suppression of mast cell degranulation is involved in the efficacy of sublingual immunotherapy2019
- Author(s)
  Kaminuma O, Kitamura N, Gotoh M, Shindo M, Watanabe N, Saeki M, Nishimura T, Mori A, Nemoto S, Tatsumi H, Okubo K, Hiroi T.
- Journal Title
  
  Allergol. Int.
  
  Volume: 68 Issue: Supplement.1 Pages: S9-S10
- DOI
  10.1016/j.alit.2019.03.007
- NAID
  130007709743
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07190, KAKENHI-PROJECT-18K08422, KAKENHI-PROJECT-19K09901
[Journal Article] Involvement of taste receptors in the effectiveness of sublingual immunotherapy2018
- Author(s)
  Gotoh Minoru、Kaminuma Osamu、Nakaya Akihiro、Katayama Kazufumi、Watanabe Nobumasa、Saeki Mayumi、Nishimura Tomoe、Kitamura Noriko、Okubo Kimihiro、Hiroi Takachika
- Journal Title
  
  Allergol. Int.
  
  Volume: 67 Issue: 3 Pages: 421-424
- DOI
  10.1016/j.alit.2018.02.003
- NAID
  130007420446
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08626
[Journal Article] Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells2018
- Author(s)
  Kaminuma Osamu、Kitamura Noriko、Nishito Yasumasa、Nemoto Soichi、Tatsumi Hideki、Mori Akio、Hiroi Takachika
- Journal Title
  
  The Journal of Immunology
  
  Volume: 200 Issue: 1 Pages: 92-100
- DOI
  10.4049/jimmunol.1602113
- Open Access
- Data Source
  KAKENHI-PROJECT-18K08422
[Journal Article] Contribution of neuraminidase 3 to the differentiation of induced regulatory T cells2018
- Author(s)
  Kaminuma Osamu、Katoh Shigeki、Miyagi Taeko、Watanabe Nobumasa、Kitamura Noriko、Nishimura Tomoe、Saeki Mayumi、Mori Akio、Hiroi Takachika
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 2 Pages: 112-116
- DOI
  10.1111/gtc.12553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08422
[Journal Article] Effects of anti-allergic drugs on T cell-mediated nasal hyperresponsiveness in a murine model of allergic rhinitis2018
- Author(s)
  Nishimura Tomoe、Kaminuma Osamu、Saeki Mayumi、Kitamura Noriko、Gotoh Minoru、Mori Akio、Hiroi Takachika
- Journal Title
  
  Allergol. Int.
  
  Volume: 67 Issue: Supplement.1 Pages: S25-S31
- DOI
  10.1016/j.alit.2018.05.002
- NAID
  130007485137
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08422, KAKENHI-PROJECT-18K19561
[Journal Article] Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis2017
- Author(s)
  Gotoh Minoru、Kaminuma Osamu、Nakaya Akihiro、Katayama Kazufumi、Motoi Yuji、Watanabe Nobumasa、Saeki Mayumi、Nishimura Tomoe、Kitamura Noriko、Yamaoka Kazuko、Okubo Kimihiro、Hiroi Takachika
- Journal Title
  
  Int Immunol
  
  Volume: 29 Issue: 6 Pages: 291-300
- DOI
  10.1093/intimm/dxx034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08626
[Journal Article] Hyper-reactive cloned mice generated by direct nuclear transfer of antigen-specific CD4+ T cells.2017
- Author(s)
  Kaminuma O, Katayama K, Inoue K, Saeki M, Nishimura T, Kitamura N, Shimo Y, Tofukuji S, Ishida S, Ogonuki N, Kamimura S, Oikawa M, Katoh S, Mori A, Shichijo M, Hiroi T, Ogura A
- Journal Title
  
  EMBO Reports
  
  Volume: 印刷中 Issue: 6 Pages: 885-893
- DOI
  10.15252/embr.201643321
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25112009, KAKENHI-PROJECT-26461497, KAKENHI-PROJECT-15K07787
[Journal Article] Rapid development of antigen-induced airway inflammation in cloned mice generated by nuclear transfer of antige-specific CD4<sup>+</sup> T cells2017
- Author(s)
  Kaminuma Osamu、Inoue Kimiko、Saeki Mayumi、Katayama Kazufumi、Mori Akio、Ogura Atsuo
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 150 Issue: 2 Pages: 83-87
- DOI
  10.1254/fpj.150.83
- NAID
  130005936794
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-15K07787
[Journal Article] Transgenic plants for allergen-specific immunotherapy.2014
- Author(s)
  Nishimura T, Saeki M, Kaminuma O, Takaiwa F, Hiroi T.
- Journal Title
  
  World J Immunol
  
  Volume: 4 Issue: 3 Pages: 141-148
- DOI
  10.5411/wji.v4.i3.141
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500501, KAKENHI-PROJECT-24791817
[Journal Article] Antigen-Induced Mixed and Separated Inflammation in Murine Upper and Lower Airways2014
- Author(s)
  Saeki M, Nishimura T, Mori A, Kaminuma O, Hiroi T.
- Journal Title
  
  Allergol. Int.
  
  Volume: 63 Issue: Supplement.1 Pages: S59-S61
- DOI
  10.2332/allergolint.13-LE-0634
- NAID
  130004477223
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500501, KAKENHI-PROJECT-26461497
[Journal Article] Food allergen-induced IgE response mouse model created by injection of in vitro differentiated Th2 cell culture and oral antigen intake.2014
- Author(s)
  Shibahara K, Nakajima-Adachi H, Kaminuma O, Hiroi T, Mori A, Hachimura S.
- Journal Title
  
  Biosci Microb Food Health
  
  Volume: 31 Pages: 41-46
- NAID
  130004562682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500501
[Journal Article] Selective Suppression of Th2 Cell-Mediated Lung Eosinophilic Inflammation by Anti-Major Facilitator Super Family Domain Containing 10 Monoclonal Antibody2014
- Author(s)
  Nishimura T, Saeki M, Motoi Y, Kitamura N, Mori A, Kaminuma O, Hiroi T.
- Journal Title
  
  Allergol. Int.
  
  Volume: 63 Issue: Supplement.1 Pages: S29-S35
- DOI
  10.2332/allergolint.13-OA-0635
- NAID
  130004477230
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500501, KAKENHI-PROJECT-26461497
[Journal Article] IL-17A Induces Hypo-contraction of Intestinal Smooth Muscle via Induction of iNOS in Muscularis Macrophages2014
- Author(s)
  Mori D, Watanabe N, Kaminuma O, Murata T, Hiroi T, Ozaki H, Hori M.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 125 Issue: 4 Pages: 394-405
- DOI
  10.1254/jphs.14060FP
- NAID
  130004677798
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24248050, KAKENHI-PROJECT-24500501, KAKENHI-PROJECT-25660224
[Journal Article] Existence of antigen-specific IgE is not sufficient for allergic nasal eosinophil infiltration in mice.2013
- Author(s)
  Nishimura T, Saeki M, Kaminuma O, Matsuoka K, Yonekawa H, Mori A, Hiroi T.
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 161: Issue: Suppl. 2 Pages: 125-128
- DOI
  10.1159/000350565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500501
[Journal Article] NFAT1 and NFAT2 differentially regulate IL-17A expression in human T cells.2012
- Author(s)
  Kaminuma O, Kitamura N, Mori A, Tatsumi H, Nemoto S, Hiroi T.
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 158 Issue: Suppl. 1 Pages: 30-34
- DOI
  10.1159/000337757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590107
[Journal Article] CD44 is critical for airway accumulation of antigen-specific Th2 cells, but not Th1 cells, induced by antigen challenge in mice2011
- Author(s)
  Kato S, Kaminuma O, Hiroi T, Mori A, Ohtomo T, Maeda S, Shimizu H, Obase Y, Oka M
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Pages: 3198-3207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] Zinc finger protein, multitype 1 suppresses human Th2 development via down-regulation of IL-42011
- Author(s)
  Kitamura N, Kaminuma O, et al
- Journal Title
  
  International Archives of Allegy and Immunology
  
  Volume: VOL.155 Issue: Suppl. 1 Pages: 53-56
- DOI
  10.1159/000327292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086, KAKENHI-PROJECT-21590978
[Journal Article] Zinc finger protein, multitype 1 suppresses human Th2 development via down-regulation of IL-42011
- Author(s)
  Kitamura N, Mori A, Tatsumi H, Nemoto S, Miyoshi H, Miyatake S, Kitamura F, Hiroi T, Kaminuma O
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] Comparative analysis of steroid sensitivity of Th cells in vitro and in vivo2011
- Author(s)
  Abe A, Kaminuma O, et al
- Journal Title
  
  International Archives of Allegy and Immunology
  
  Volume: VOL.155 Issue: Suppl. 1 Pages: 110-116
- DOI
  10.1159/000327494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086, KAKENHI-PROJECT-21590978, KAKENHI-PROJECT-22790773
[Journal Article] CD44 is critical for airway accumulation of antigen-specific Th2 cells, but not Th1 cells, induced by antigen challenge in mice2011
- Author(s)
  Kato S, Kaminuma O, et al
- Journal Title
  
  European Journal of Immunology
  
  Volume: 41 Issue: 11 Pages: 3198-3207
- DOI
  10.1002/eji.201141521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086, KAKENHI-PROJECT-21590978
[Journal Article] Comparative analysis of steroid sensitivity of Th cells in vitro and in vivo2011
- Author(s)
  Abe A, Ohtomo T, Koyama S, Kitamura N, Kaminuma O, Mori A
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] Selective suppression of Th2 cytokines by C-terminal binding protein 2 in human T cells.2010
- Author(s)
  Kitamura Fujiko, Kaminuma Osamu, et al.
- Journal Title
  
  International Archives of Allergy and Immunology
  
  Volume: VOL.152 Pages: 18-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] Eosinophils are required for the induction of bronchial hyperresponsiveness in a Th-transfer model of Balb/c background2010
- Author(s)
  Ohtomo T, Kaminuma O, Kitamura N, Suko M, Kobayashi N, Mori A
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] Eosinophils are required for the induction of bronchial hyperresponsiveness in a Th-transfer model of Balb/c background.2010
- Author(s)
  Ohtomo Takayuki, Kaminuma Osamu, et al.
- Journal Title
  
  International Archives of Allergy and Immunology
  
  Volume: VOL.152 Pages: 79-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] Selective suppression of Th2 cytokines by C-terminal binding protein 2 in human T cells2010
- Author(s)
  Kitamura F, Kitamura N, Mori A, Tatsumi H, Nemoto S, Miyoshi H, Miyatake S, Hiroi T, Kaminuma O
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] NFATサブタイプ阻害薬開発の意義と可能性2009
- Author(s)
  神沼修
- Journal Title
  
  薬学研究の進歩
  
  Volume: 25 Pages: 7-10
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] NEATサブタイプ阻害薬の意義と可能性2009
- Author(s)
  神沼修
- Journal Title
  
  薬学研究の進歩 25
  
  Pages: 7-10
- Data Source
  KAKENHI-PROJECT-21590086
[Journal Article] GATA-3 suppresses IFN-γ promoter activity independently of binding to cis-regulatory elements.2004
- Author(s)
  Kaminuma, O., Kitamura, F., Kiramura, N., Miyagishi, M., Taira, K., Yamamoto, K., Miura, O., Miyatake, S.
- Journal Title
  
  FEBS Lett. 570
  
  Pages: 53-58
- Data Source
  KAKENHI-PROJECT-16043263
[Presentation] 酪酸はIgE非依存的マスト細胞活性化を抑制する2024
- Author(s)
  森田莉加、長田　和樹、谷萩　祐太、岡村　穂丘、山崎　憲政、三浦　健人、神沼　修、西山　千春
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] 草菌ゲノムベクターを用いたヒトTCR遺伝子座の再構築2024
- Author(s)
  諸角　光祐、岩田　哲郎、山崎　憲政、神沼　修、廣田　順二
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Biological and biochemical analysis of T cell derived bronchoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasaki, Y., Iwata, M., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  European Respiratory Society 2023 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Cellular and molecular analysis of T cell-dependent steroid-resistant asthma model2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasaki, Y., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  Asia Pacific Society of Respirology 2023 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] 制御性T細胞におけるニコチン性アセチルコリン受容体の発現と機能2023
- Author(s)
  神沼　修、三浦　健人、山崎　憲政、尾形　佐和子、三浦　舟華、細見　直永、中田　雄一郎、後藤　穣
- Organizer
  第53回日本職業・環境アレルギー学会総会
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Effect of ionizing-radiation exposure on improved genome-editing via oviductal nucleic acids delivery (i-GONAD).2023
- Author(s)
  Bold-Erdene A, Miura K, Yamazaki N, Kaminuma O.
- Organizer
  7th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] 放射線照射がT細胞依存性皮膚炎症に与える影響を評価するマウスモデルの作出2023
- Author(s)
  三浦　健人、Enkhbaatar Uyanga、尾形　佐和子、山崎　憲政、神沼　修
- Organizer
  第７回放射線災害・医科学研究拠点カンファランス
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Cellular Analysis of T cell-dependent steroid-resistant asthma2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasaki, Y., Nakamura, Y., Kamide, Y., Sekiya, K., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  Asia Pacific Association of Allergy, Asthma and Clinical Immunology International Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] 喘息を中心とした2型炎症の免疫調節機構2023
- Author(s)
  神沼　修
- Organizer
  第89回臨床アレルギー研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Biochemical analysis of T cell dependent bronchoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Tawasaki, Y., Iwata, M., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O., and Mori, A.
- Organizer
  American Academy of Allergy Asthma & Immunology Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] マウスTh17細胞依存的アレルギー性皮膚炎症モデルに対する抗アレルギー外用薬の効果2023
- Author(s)
  田尾　友記子、三浦　健人、Mirkatouli Fatemeh Beygom、Enkhbaatar Uyanga、山崎　憲政、宇田　直人、尾形　佐和子、森　晶夫、神沼　修
- Organizer
  アレルギー・好酸球研究会２０２３
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Pharmacological characterization of T cell-induced bronchoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasai, Y., Iwata, M., Nakamura, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  World Allergy Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] アレルギー性鼻炎発症に果たすα7-ニコチン性アセチルコリン受容体の役割2023
- Author(s)
  尾形　佐和子、三浦　健人、山下　修平、山崎　憲政、宇田　直人、松浦　安那、中嶋　正太郎、森　晶夫、後藤　穣、神沼　修
- Organizer
  第72回日本アレルギー学会総会
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] COVID-19モデルとしてのヒトACE2ノックインマウス作出とSARS-CoV-2感染病態の評価2023
- Author(s)
  三浦　健人、福士　雅也、山崎　憲政、山中　亮憲、坂口剛正、神沼　修
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Biochemical characterization of T cell derived bronvhoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasai, Y., Iwata, M., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  European Academy of Allergy and Clinical Immunology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Suppressive effect of a LAT1 specific inhibitor on a murine model of Th17-dependent steroid-resistant asthma2022
- Author(s)
  林　啓太朗、佐伯真弓、遠藤　仁、神沼　修
- Organizer
  第95回年会日本薬理学会年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Novel functional cell delivery system based on allergic inflammatory responses.2022
- Author(s)
  神沼　修
- Organizer
  第96回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] OVA特異的T細胞クローンマウスにおける経口抗原に対する応答とTCR遺伝子使用の解析2022
- Author(s)
  塩原幸、五島直樹、佐伯祐輔、王イバイ、中川稜悟、曽我皓平、王蓉、神沼修、足立（中嶋）はるよ、八村敏志
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Steroid resistance of severe asthma - mechanisms and therapeutic targets2022
- Author(s)
  森晶夫、神山智、大友暁美、山口美也子、組谷千恵美、岩本圭右、矢野光一、藤田教寛、岩田真紀、永山貴紗子、劉楷、中村祐人、濱田祐斗、渡井健太郎、上出庸介、福富　友馬、関谷　潔史、松元　幸一郎、谷口　安、小林　信之、大友　隆之、神沼　修
- Organizer
  第95回年会日本薬理学会年会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Control of T cell-dependent steroid-resistant asthma model by several kinase inhibitors2022
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Ohtomo-Abe, A., Iwamoto, K., Yano, K., Fujita, N., Iwata, M., Nagayama K., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O.
- Organizer
  European Respiratory Society International Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] 重症喘息のステロイド抵抗性とその制御2022
- Author(s)
  森　晶夫、神山　智、大友暁美、山口美也子、組谷千恵美、岩本圭右、矢野光一、藤田教寛、岩田真紀、永山貴紗子、劉　楷、中村祐人、濱田祐斗、渡井健太郎、上出庸介、福冨友馬、関谷潔史、松元幸一郎、谷口　安、小林信之、大友隆之、神沼　修
- Organizer
  第95回日本薬理学会年会　シンポジウム27　難治性ぜんそく治療への新たな挑戦
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] T cell-dependent steroid-resistant asthma is mediated by tyrosine kinases of costimulatory signal2022
- Author(s)
  Mori, A., Kouyama, S., Ohtomo-Abe, A., Iwamoto, K., Yano, K., Fujita, N., Iwata, M., Nagayama, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology Hybrid Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] T細胞による味覚センシングとアレルギー．2022
- Author(s)
  神沼　修
- Organizer
  日本食品免疫学会第18回学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00398
[Presentation] Possible mechanisms of T cell-induced bronchoconstriction2021
- Author(s)
  Mori, A., Kouyama, S., Ohtomo-Abe, A., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Ohtomo, T., Kaminuma, O.
- Organizer
  Asia Pacific Association of Allergy, Asthma and Clinical Immunology International Conference 2021 (Taipei, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] OVA特異的T細胞クローンマウスを用いた経口抗原に対するCD4+T細胞応答の解析2021
- Author(s)
  塩原幸、五島直樹、王イバイ、中川稜悟、曽我皓平、王蓉、神沼修、足立（中嶋）はるよ、八村敏志
- Organizer
  日本農芸化学会2021年度大会（仙台）
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Sublingual immunotherapy suppresses mast cell degranulation through the upregulation of thrombospondin-12021
- Author(s)
  Kaminuma, O., Kitamura, N., Gotoh, M., Okubo, K., Mori, A., and Hiroi, T.
- Organizer
  European Academy of Allergy and Clinical Immunology Hybrid Congress 2021 (Madrid-Krakow, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] OVA特異的T細胞クローンマウスによる経口抗原に対するCD4+T細胞応答の解析2021
- Author(s)
  塩原　幸、五島　直樹、Wang Yimei、中川　稜悟、曽我　皓平、王　蓉、西村　友枝、北村　紀子、佐伯　真弓、廣井　隆親、神沼　修、足立（中嶋）はるよ、八村　敏志
- Organizer
  第70回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] T細胞依存的に発症する新しいアレルギー性皮膚炎モデル2021
- Author(s)
  尾形佐和子、三浦健人、吉川日出夫、森　晶夫、廣井隆親、神沼　修
- Organizer
  第70回日本アレルギー学会学術大会（横浜）
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] T細胞依存性アレルギー性炎症に対するLAT1阻害薬の効果2021
- Author(s)
  神沼修、佐伯真弓、西村友枝、廣井隆親、三浦健人、山崎憲政、尾形佐和子、伊藤大起、古山禎大、森晶夫、遠藤仁、安西尚彦、林啓太朗
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Molecular characterization of bronchoconstriction induced by activated T cells2021
- Author(s)
  Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Kawasaki, Y., Iwamoto, K., Yano, K., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Ohtomo, T., Kaminuma, O, and Mori, A.
- Organizer
  European Respiratory Society 2021 International Congress (London, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Th17細胞依存的マウス鼻粘膜炎症モデルに対するdexamethasoneの効果2021
- Author(s)
  三浦健人、上田周作、山崎憲政、尾形佐和子、川崎英利、森　晶夫、神沼　修
- Organizer
  アレルギー・好酸球研究会2021
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Pharmacological characterization of T cell-induced bronchoconstriction in vivo and in vitro2021
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, Y., Kumitani, C., Ohtomo-Abe, A., Kawasaki, Y., Iwamoto, K., Yano, K., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., and Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology Hybrid Congress 2021　(Madrid-Krakow, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Th17細胞依存的ステロイド抵抗性喘息モデルに対するアミノ酸トランスポーターLAT1阻害薬の効果2021
- Author(s)
  林啓太朗、佐伯真弓、三浦健人、山崎憲政、尾形佐和子、森　晶夫、廣井隆親、遠藤　仁、神沼　修
- Organizer
  アレルギー・好酸球研究会2021
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Generation of chimeric mice with organs fully derived from embryonic stem cells with genetic mutations causing lethality.2021
- Author(s)
  iura K, Matoba S, Hirose M, Kaminuma O, Ogura A
- Organizer
  第5回放射線災害・医科学研究拠点国際シンポジウム（広島）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] L-type amino acid transporter 1 is essential for Th2 cell-mediated allergic inflammation2021
- Author(s)
  Kaminuma O, Miura K, Yamasaki N, Ogata S, Saeki M, Hiroi T, Iwata Y, Sugiura K, Mori A, Endou H, Hayashi K
- Organizer
  Immunology 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Th9細胞依存的なアレルギー性炎症は標的臓器間で異なるステロイド応答性を示す2021
- Author(s)
  三浦健人、佐伯真弓、古山禎大、山崎憲政、尾形佐和子、廣井隆親、森　晶夫、神沼　修
- Organizer
  第70回日本アレルギー学会学術大会（横浜）
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Role of Costimulatory Signal in T Cell-Dependent Steroid-Resistant Asthma2020
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Kumitani C, Ohtomo-Abe A, Ryu K, Nakamura Y, Hamada Y, Fujita N, Hayashi H, Watai K, Kamide Y, Sekiya K, Fukutomi Y, Taniguchi M, Matsumoto K, Tanimoto Y, Nobuyuki, Kobayashi N, Ohtomo T, Kaminuma O
- Organizer
  ERS International Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Th9細胞移入マウスにおけるアレルギー性鼻粘膜炎症とステロイド抵抗性の解析2020
- Author(s)
  古山禎大、三浦健人、山崎憲政、尾形佐和子、伊藤大起、森　晶夫、廣井隆親、佐伯真弓、神沼修
- Organizer
  アレルギー・好酸球研究会２０２０
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] ヒトACE2導入マウスと抗原特異的T細胞クローンマウスの開発2020
- Author(s)
  神沼　修
- Organizer
  ファーマラボEXPOアカデミックフォーラム（幕張）
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Genome-wide transcriptome and copy number variation analysis for sublingual immunotherapy.2020
- Author(s)
  Kaminuma O, Gotoh M, Nakaya A, Saeki M, Nishimura T, Kitamura N, Watanabe N, Okubo K, Hiroi T.
- Organizer
  JSA/WAO Joint Congress 2020 (Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09901
[Presentation] The contribution of L-type amino acid transporter 1 in activated Th2 cells for the development of atopic dermatitis2020
- Author(s)
  Kaminuma, O., Hayashi, K., Nishimura, T., Saeki, M., Hiroi, T., Iwata, Y., Sugiura, K., Mori, A.
- Organizer
  JSA/WAO XXVII World Allergy Congress (WAC 2020) conjoint with the APAPARI 2020 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] The contribution of L-type amino acid transporter 1 in activated Th2 cells for the development of atopic dermatitis2020
- Author(s)
  Kaminuma O, Hayashi K, Nishimura T, Saeki M, Hiroi T, Iwata Y, Sugiura K, Mori A
- Organizer
  JSA/WAO Joint Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Pharmacological analysis of T cell-dependent steroid-resistant asthma2020
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Yano, K., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Taniguchi, Ohtomo, T., and Kaminuma, O.
- Organizer
  European Respiratory Society 2020 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Th9 cells elicit bronchial hyperresponsiveness through eosinophil-independent mechanisms2020
- Author(s)
  Saeki Mayumi, Kaminuma Osamu, Hiroi Takachika
- Organizer
  第93回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] L型アミノ酸トランスポーター1阻害薬のＴh2細胞依存性気管支喘息モデルに対する効果2020
- Author(s)
  伊藤大起、佐伯真弓、三浦健人、山崎憲政、尾形佐和子、古山禎大、廣井隆親、森晶夫、遠藤仁、林啓太朗、神沼修
- Organizer
  アレルギー・好酸球研究会２０２０
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] An inhibitory factor for mast cell degranulation induces by sublingual immunotherapy2020
- Author(s)
  Kaminuma, O., Gotoh, M., Kitamura, N., Shindo, M., Watanabe, N., Saeki, M., Nishimura, T., Mori, A., Nemoto, S., Tatsumi, H., Okubo, K., Hiroi, T.
- Organizer
  JSA/WAO XXVII World Allergy Congress (WAC 2020) conjoint with the APAPARI 2020 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Antigen-specific T cells confer nasal hyperresponsiveness in murine models of allergic rhinitis.2020
- Author(s)
  Kaminuma O, Nishimura T, Hiroi T, Yamasaki N, Ogata S, Mori A
- Organizer
  EAACI Congress 2020（London）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03145
[Presentation] Pharmacological analysis of helper T cell-dependent, steroid-resistant asthma2020
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Kumitani C, Ohtomo-Abe A, Fujita N, Nagayama K, Iwata M, Ryu K, Nakamura Y, Hamada Y, Hayashi H, Watai K, Kamide Y, Sekiya K, Fukutomi Y, Taniguchi M, Ohtomo T, Kaminuma O
- Organizer
  EAACI Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Pharmacological analysis of helper T cell-dependent, steroid-resistant asthma2020
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Synergistic suppression of T cell-induced eosinophilia by glucocorticoid and CTLA4-Ig2019
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Kumitani C, Ohtomo-Abe A, Fujita N, Iwata M, Nagayama K, Ryu K, Nakamura Y, Tomita Y, Hamada Y, Hayashi H, Watai K, Kamide Y, Sekiya K, Fukutomi Y, Taniguchi M, Ohtomo T, Kaminuma O
- Organizer
  American Academy of Allergy Asthma & Immunology 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Pharmacological analysis of T cellinduced bronchoconstriction in vitro and in vivo2019
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Kumitani C, Ohtomo-Abe A, Fujita N, Iwata M, Nagayama K, Ryu K, Nakamura Y, Tomita Y, Hamada Y, Hayashi H, Watai K, Kamide Y, Sekiya K, Fukutomi Y, Taniguchi M, Ohtomo T, Kaminuma O
- Organizer
  European Academy of Allergy and Clinical Immunology Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Control of steroid resistance by blocking costimulatory signal2019
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  WAO International Scientific Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Synergistic suppression of T cell-induced eosinophilia by glucocorticoid and CTLA4-Ig2019
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  American Academy of Allergy Asthma & Immunology Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Differential mechanisms of Th2- and Th9-mediated bronchial hyperresponsiveness in mice2019
- Author(s)
  Kaminuma Osamu, Saeki Mayumi, Nishimura Tomoe, Kitamura Noriko, Mori Akio, Hiroi Takachika
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Pharmacological characterization of T cell-induced broncho-constriction2019
- Author(s)
  constrictionMori A, Kouyama S, Yamaguchi M, Kumitani C, Ohtomo-Abe A, Fujita N, Iwata M, Nagayama K, Ryu K, Nakamura Y, Tomita Y, Hamada Y, Hayashi H, Watai K, Kamide Y, Sekiya K, Fukutomi Y, Taniguchi M, Ohtomo T, Kaminuma O
- Organizer
  ATS International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] CD28 signal blockade as a treatment for steroid resistant asthma2019
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] T cell-induced bronchoconstriction in mice2018
- Author(s)
  Kouyama, S., Ohtomo, T., Kaminuma, O., and Mori, A.
- Organizer
  American College of Allergy and Immunology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Mechanisms of nonatopic, T cell-induced bronchoconstriction.2018
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  WAO International Scientific Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] アレルギー性鼻炎のメカニズムと抗原特異的免疫療法に対する実験動物学的解析2018
- Author(s)
  神沼　修
- Organizer
  第３７回日本耳鼻咽喉科免疫アレルギー大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] T細胞の核移植によるアレルギー疾患モデルマウス2018
- Author(s)
  神沼　修
- Organizer
  第55回筑波実験動物研究会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Pharmacological characterization of T cell-induced broncho-constriction in vitro and in vivo.2018
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  European Respiratory Society 2018 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Pharmacological characterization of T cell-induced broncho-constriction in vitro and in vivo2018
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Kumitani C, Ohtomo-Abe A, Fujita N, Iwata M, Nagayama K, Ryu K, Nakamura Y, Tomita Y, Hamada Y, Hayashi H, Watai K, Kamide Y, Sekiya K, Fukutomi Y, Taniguchi M, Ohtomo T, Kaminuma O
- Organizer
  RS International Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] Differential property of murine airway eosinophilic inflammation induced by Th2 and Th9 cells2018
- Author(s)
  Saeki M, Kaminuma O, Nishimura T, Kitamura N, Mori A, Hiroi T
- Organizer
  XXIV World Congress of Asthma
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19561
[Presentation] 抗原特異的CD4陽性T細胞由来の核移植クローンマウス作製2017
- Author(s)
  井上　貴美子、神沼　修、越後貫　成美、上村　悟氏、及川　真実、的場　章悟、廣井　隆親、小倉　淳郎
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] アレルギー疾患におけるT細胞の重要性と核移植クローン技術による新規モデル開発2017
- Author(s)
  神沼　修
- Organizer
  第７６回鳥取大学染色体工学研究センターセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] Establishment of non-transgenic monoclonal T cell receptor-expressing mice2017
- Author(s)
  Kaminuma O, Katayama K, Kitamura N, Shimo Y, Mori A
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] 抗原特異的CD4陽性T細胞由来クローンマウスのアレルギー性気道炎症2017
- Author(s)
  神沼　修、井上貴美子、佐伯　真弓、西村　友枝、北村　紀子、森　晶夫、廣井　隆親、小倉　淳郎
- Organizer
  第64回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] Cloned mice derived from antigen-specific CD4+ T cells for the study of inflammation and aging2017
- Author(s)
  Ogura A, Inoue K, Saeki M, Matoba S, Nishimura T, Kitamura N, Mori A, Hiroi T, Kaminuma O
- Organizer
  RIKEN aging project annual meeting
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] T細胞クローンマウスを用いた新しいアレルギー疾患モデル.2016
- Author(s)
  神沼　修
- Organizer
  第４回山梨大学医学部基礎医学系研究セミナー
- Place of Presentation
  山梨大学（山梨県中央市）
- Year and Date
  2016-04-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] 抗原特異的T細胞の核移植によるクローンマウスの作出.2016
- Author(s)
  形山和史、神沼修、井上貴美子、小倉淳郎、越後貫成美、上村悟氏、及川真実、的場章悟、井上弘貴、下茂佑輔、七條通孝.
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] 抗原特異的T細胞由来のクローンマウスはアレルギー性鼻炎様症状を急速発症する.2016
- Author(s)
  廣井隆親、西村友枝、形山和史、井上貴美子、小倉淳郎、森晶夫、七條通孝、神沼修.
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] 抗原特異的T細胞由来のクローンマウスは気管支喘息様の気道炎症を急速発症する.2016
- Author(s)
  神沼修、佐伯真弓、北村紀子、形山和史、井上貴美子、小倉淳郎、加藤茂樹、森晶夫、七條通孝、廣井隆親.
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] Hyper-reactive T cell clone mice as a model for aging study.2016
- Author(s)
  Osamu Kaminuma, Kimiko Inoue, Mayumi Saeki, Tomoe Nishimura, Noriko Kitamura, Narumi Ogonuki, Satoshi Kamimura, Mami Oikawa, Shigeki Katoh, Akio Mori, Takachika Hiroi, Atsuo Ogura.
- Organizer
  Frontiers in aging research toward healthy longevity
- Place of Presentation
  丸の内 MY PLAZA ホール（東京都千代田区）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] Rapid development of house dust mite-induced allergic inflammation2016
- Author(s)
  神沼　修
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K07787
[Presentation] Diversity of nuclear factor of activated T cells in vertebrate organisms.2014
- Author(s)
  Kaminuma O, Kitamura N, Hiroi T.
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-24590107
[Presentation] Selective down-regulation of IL-2-mediated cytokine expression in human T cells by protein phosphatase 1 inhibitors.2014
- Author(s)
  Kaminuma O, Kitamura N, Mori A, Hiroi T.
- Organizer
  Experimental Biology 2014
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-04-30
- Data Source
  KAKENHI-PROJECT-24590107
[Presentation] マウスアレルギー性鼻炎モデルにおけるIgEおよびT細胞の関与．2012
- Author(s)
  西村　友枝、佐伯　真弓、北村　紀子、神沼　修、松岡　邦枝、米川　博通、森　晶夫、廣井　隆親．
- Organizer
  第６２回日本アレルギー学会秋季学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] Antigen-specific Th2 cells specifically utilize CD44 to infiltrate into antigen-challenged lung in mice2011
- Author(s)
  Kaminuma O, Kato S, Mori A, Hiroi T
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] T細胞のIL-17産生に対するNFATファミリーの機能的相違2011
- Author(s)
  神沼修、北村紀子、北村ふじ子、巽英樹、根本荘一、宮武昌一郎、森晶夫、廣井隆
- Organizer
  アレルギー・好酸球研究会2011
- Place of Presentation
  東京
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] Comparative analysis of steroid sensitivity of Th cells in vitro and in vivo2011
- Author(s)
  Mori A, Abe A, Koyama S, Kitamura N, Yamaguchi M, Tanimoto H, Sekiya K, Oshikata C, Mitsui C, Taniguchi M, Ohtomo M, Maeda Y, Hasegawa M, Akiyama K, Ohtomo T, Kaminuma O
- Organizer
  30th Congress of the European Academy of Allergy and Clinical Immunology
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2011-06-13
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] ZFPM1/CtBP1コンプレックスはGATA-3によるTh2分化を抑制する2010
- Author(s)
  神沼修, ほか
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京国際フォーラム・東京
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] ZFPM1/CtBP1コンプレックスはGATA-3によるTh2分化を抑制する2010
- Author(s)
  神沼修,北村紀子,森晶夫,巽英樹,根本荘一,廣井隆親
- Organizer
  第60回日本アレルギー学会総会
- Place of Presentation
  東京
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] T細胞クローン移入喘息モデルによるステロイド感受性解析2010
- Author(s)
  安部暁美、神沼修, ほか
- Organizer
  アレルギー・好酸球研究会2010
- Place of Presentation
  大手町サンケイプラザ・東京
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] T細胞クローン移入喘息モデルによるステロイド感受性解析2010
- Author(s)
  安部暁美、大友隆之、神山智、北村紀子、神沼修、森晶夫
- Organizer
  アレルギー・好酸球研究会2010
- Place of Presentation
  東京
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21590086
[Presentation] ヒスタミン欠損マウスにおけるアレルギー性鼻炎病態の解析
- Author(s)
  西村　友枝、佐伯　真弓、　　大津　浩、後藤穣、大久保　公裕、森　晶夫、神沼　修、廣井隆親.
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンス新高輪（東京・港区）
- Year and Date
  2015-05-26 – 2015-05-28
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] マウスアレルギー性鼻炎モデルにおけるIgE-肥満細胞系およびT細胞の関与．
- Author(s)
  西村　友枝、佐伯真弓、松岡　邦枝、米川　博通、森　晶夫、後藤　穣、大久保　公裕、神沼　修、廣井　隆親
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] 免疫療法の治療効果を予見するバイオマーカーセット
- Author(s)
  神沼　修
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知・名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] TGF-β誘導性T細胞サブセットのアレルギー性気道炎症における役割
- Author(s)
  佐伯　真弓、西村　友枝、渡辺　伸昌、森　晶夫、神沼　修、廣井　隆親
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] Development and treatment of steroid resistant asthma model by adoptive transfer of murine helper t cell clones.
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Iijima Y, Ohtomo A, Ohtomo T, Itoh J, Hayashi H, Watarai K, Mitsui C, Oshikata C, Fukutomi Y, Sekiya K, Tsuburai T, Maeda Y, Ohtomo M, Taniguchi M, Akiyama K, Kaminuma O.
- Organizer
  WAO International Scientific Conference 2014
- Place of Presentation
  Rio de Janeiro, Brazil
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] Pharmacological characterization of T cell-induce bronchoconstriction in the mice.
- Author(s)
  Mori A, Kouyama S, Yamaguchi M, Iijima Y, Ohtomo-Abe A, Hayashi H, Watarai K, Mitsui C, Oshikata C, Sekiya K, Tsuburai T, Maeda Y, Ohtomo M, Fukutomi Y, Taniguchi M, Akiyama K, Ohtomo T, Kaminuma O.
- Organizer
  2015 American Academy of Allergy, Asthma and Immunology annual meeting
- Place of Presentation
  Huston, USA
- Year and Date
  2015-02-20 – 2015-02-24
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] Antigen-specific iTreg cells augment Th17-mediated inflammatory response in a CTLA-4-dependent fashion.
- Author(s)
  Watanabe N, Kitamura N, Mori A, Kaminuma O
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] 新しい花粉症モデル：マウスにおけるＴ細胞依存性鼻粘膜過敏性亢進反応
- Author(s)
  神沼　修、西村　友枝、佐伯　真弓、松岡　邦枝、米川　博通、後藤　穣、大久保　公裕、森　晶夫、廣井　隆親
- Organizer
  第63回日本アレルギー学会秋季学術大会、イブニングシンポジウム“東京都花粉症プロジェクト”
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] Differential contribution of calcineurin-binding regions among NFAT family members.
- Author(s)
  Kaminuma O, Kitamura N, Nemoto S, Tatsumi H, Mori A, Hiroi T.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590107
[Presentation] Th2およびTh9細胞による気道過敏性亢進発症機構の相違
- Author(s)
  佐伯　真弓、西村　友枝、渡辺　伸昌、森　晶夫、神沼　修、廣井　隆親.
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンス新高輪（東京・港区）
- Year and Date
  2015-05-26 – 2015-05-28
- Data Source
  KAKENHI-PROJECT-24500501
[Presentation] アレルギー性鼻炎における鼻粘膜過敏性亢進に対するT細胞の関与．
- Author(s)
  佐伯真弓、西村　友枝、神沼　修、森晶夫、廣井隆親．
- Organizer
  アレルギー・好酸球研究会２０１３
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500501

1. Hosomi Naohisa (70363190)

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2. Hori Masatoshi (70211547)

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KAMINUMA Osamu 神沼 修

神沼 修 カミヌマ オサム

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核移植クローン技術に基づく免疫応答・疾患発症機構の包括的研究基盤Principal Investigator

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Usefulness of T cell cloned mice as bioresources for immunological sciencePrincipal Investigator

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Mechanisms underlying the development of hyperresponsiveness commonly induced by T cell subsets in allergic diseasesPrincipal Investigator

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Elucidation of immune function through antigen-specific monoclonal T cell receptorPrincipal Investigator

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KAMINUMA Osamu 神沼修

神沼修カミヌマオサム