Kodama Yuzo 児玉裕三

… Alternative Names

KODAMA Yuzo 児玉裕三

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Researcher Number	80378687
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 神戸大学, 医学研究科, 教授 2016 – 2017: 京都大学, 医学研究科, 講師 2016: 京都大学, 医学研究科, 助教 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2010 – 2012: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Basic Section 54020:Connective tissue disease and allergy-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Basic Section 48040:Medical biochemistry-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery
Keywords	Principal Investigator 自己抗体 / 自己抗原 / 自己免疫性膵炎 / IgG4関連疾患 / 前癌病変 / 膵臓 / Hes1 / Notchシグナル / 膵癌 / IgG4関連硬化性胆管炎 … More / 原発性硬化性胆管炎 / 潰瘍性大腸炎 / シグナル伝達 / 遺伝子 / 癌 / 肝細胞癌 / JNK / 肝線維化 / NASH … More Except Principal Investigator 膵癌 / オルガノイド / 腸内細菌 / 自己免疫性膵炎 / エクソソーム / 早期発見 / 繊維化 / 膵管擦過細胞診 / EUS-FNA / ゼノグラフト / PanIN / 早期膵癌 / 免疫チェックポイント阻害剤 / irAE / irAE腸炎 / 腸内細菌叢 / 予後 / 腫瘍内免疫細胞 / 細菌 / 腫瘍免疫 / 細菌叢 / 腸管免疫グロブリン / 腸管免疫 / iPS細胞 / 遺伝性膵炎 / 抗原 / Extracellular matrix / IgG4 / IgG / 自己抗体 / IgG4関連疾患 / RUNX3 / 発癌予防 / 遺伝子診断 / 分子生物学 / 癌抑制遺伝子 / 胃癌 Less

消化器指定難病と免疫関連有害事象に共通する自己免疫機構の解明およびその臨床応用Principal Investigator
- Principal Investigator
  
  児玉裕三
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
膵癌における間質繊維化機序の解明と薬物療法の効果予測への応用
- Principal Investigator
  
  飛松和俊
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kobe University
Identification of diagnostic biomarkers for early detection of pancreatic cancer using early-stage pancreatic cancer organoids.
- Principal Investigator
  
  増田充弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
自己抗原の同定に基づいた消化器系難病の病態解明と新しい診療体系の確立Principal Investigator
- Principal Investigator
  
  児玉裕三
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
早期膵癌オルガノイドの樹立による腫瘍進展機構の解明
- Principal Investigator
  
  塩見英之
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hyogo Medical University
Elucidation of the pathogenesis of immune-related adverse events caused by immune checkpoint inhibitors and search for biomarkers
- Principal Investigator
  
  Tobimatsu Kazutoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kobe University
Role of intestinal bacteria in the pathogenesis of autoimmune pancreatitis
- Principal Investigator
  
  Inoue Jun
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
Tumor microenvironment and gut microbiota in pancreatic cancer
- Principal Investigator
  
  Masuda Atsuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
Elucidation of pathophysiology and establishment of new diagnostic system for IgG4-related disease by autoantigen identificationPrincipal Investigator
- Principal Investigator
  
  Kodama Yuzo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kobe University
Development of novel therapy for pancreatic cancer targeting Notch/Hes1 signalingPrincipal Investigator
- Principal Investigator
  
  Kodama Yuzo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
  Kyoto University
Establishment of hereditary pancreatitis patient-derived iPS cells
- Principal Investigator
  
  Masamune Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Elucidation of pathophysiology and development of treatment for IgG4-related disease (RD)
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
The role of Notch/Hes1 signaling in the maintenance of homeostasis and carcinogenesis in pancreasPrincipal Investigator
- Principal Investigator
  
  Kodama Yuzo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Analysis of novel gastric tumor suppressor RUNX3 for the clinical application of gastric cancer treatment
- Principal Investigator
  
  sakakura chouhei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
The role of JNK signaling in the development of nonalcoholic steatohepatitisPrincipal Investigator
- Principal Investigator
  
  KODAMA Yuzo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University

All 2022 2021 2020 2019 2018 2017 2016 2012 2011 2010

All Journal Article Presentation Book

[Book] 【診療ガイドライン改訂後の膵炎診療】EUS所見は何を見ているのか　組織像との対比など2022
- Author(s)
  猪股典子、山川康平、増田充弘、児玉裕三
- Total Pages
  7
- Publisher
  肝胆膵
- Data Source
  KAKENHI-PROJECT-19K08444
[Book] 【膵臓症候群(第3版)-その他の膵臓疾患を含めて-】膵炎　1型自己免疫性膵炎(IgG4関連膵炎)2021
- Author(s)
  酒井新、増田充弘、児玉裕三
- Total Pages
  5
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-19K08444
[Book] 【肝・胆道系症候群(第3版)-その他の肝・胆道系疾患を含めて-肝外胆道編】肝外胆管(胆管、胆嚢管、総胆管)　その他　Oddi括約筋機能不全2021
- Author(s)
  酒井新、増田充弘、児玉裕三
- Total Pages
  3
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-19K08444
[Journal Article] Constitution of mucosa‐associated microbiota in the lower digestive tract does not change in early stage of non‐alcoholic fatty liver disease with fecal dysbiosis2022
- Author(s)
  Asaji Naoki、Inoue Jun、Hayashi Hiroki、Tokunaga Eri、Shimamoto Yusaku、Kinoshita Masato、Tanaka Takeshi、Sakai Arata、Yano Yoshihiko、Ueda Yoshihide、Kodama Yuzo
- Journal Title
  
  JGH Open
  
  Volume: 6 Issue: 10 Pages: 677-684
- DOI
  10.1002/jgh3.12803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07938, KAKENHI-PROJECT-19K08468
[Journal Article] Estimation of pancreatic fibrosis and prediction of postoperative pancreatic fistula using extracellular volume fraction in multiphasic contrast-enhanced CT2022
- Author(s)
  Sofue K, Ueshima E, Masuda A, Shirakawa S, Zen Y, Ueno Y, Tsujita Y, Yamaguchi T, Yabe S, Tanaka T, Inomata N, Toyama H, Fukumoto T, Kodama Y, Murakami T.
- Journal Title
  
  Eur Radiol.
  
  Volume: 32(3) Issue: 3 Pages: 1770-1780
- DOI
  10.1007/s00330-021-08255-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08444, KAKENHI-PROJECT-19K08152
[Journal Article] Acute pancreatitis in intraductal papillary mucinous neoplasms correlates with pancreatic volume and epithelial subtypes2021
- Author(s)
  Tanaka T, Masuda A, Sofue K, Toyama H, Shiomi H, Sakai A, Kobayashi T, Tanaka S, Nakano R, Yamada Y, Ashina S, Tsujimae M, Yamakawa K, Abe S, Gonda M, Masuda S, Inomata N, Uemura H, Kohashi S, Nagao K, Kanzawa M, Itoh T, Fukumoto T, Kodama Y.
- Journal Title
  
  Pancreatology
  
  Volume: 21 Issue: 1 Pages: 138-143
- DOI
  10.1016/j.pan.2020.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08152, KAKENHI-PROJECT-19K08444
[Journal Article] Review of Diagnostic Biomarkers in Autoimmune Pancreatitis: Where Are We Now?2021
- Author(s)
  Yokode M, Shiokawa M, Kodama Y.
- Journal Title
  
  Diagnostics
  
  Volume: 11 Issue: 5 Pages: 770-770
- DOI
  10.3390/diagnostics11050770
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03698, KAKENHI-PROJECT-21H02901
[Journal Article] The clinical efficacy of azathioprine as maintenance treatment for autoimmune pancreatitis: a systematic review and meta-analysis.2021
- Author(s)
  Masaki Y, Nakase H, Tsuji Y, Nojima M, Shimizu K, Mizuno N, Ikeura T, Uchida K, Ido A, Kodama Y, Seno H, Okazaki K, Nakamura S, Masamune A.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 56 Issue: 10 Pages: 869-880
- DOI
  10.1007/s00535-021-01817-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03698, KAKENHI-PROJECT-21K07943
[Journal Article] Phenotyping of IgG4-related diseases based on affected organ pattern: A multicenter cohort study using cluster analysis.2020
- Author(s)
  Niwamoto T, Handa T, Matsui S, Yamamoto H, Yoshifuji H, Abe H, MatsumotoH, Kodama Y, Chiba T, Seno H, Mimori T, Hirai T.
- Journal Title
  
  Modern Rheumatology
  
  Volume: in press Issue: 1 Pages: 235-240
- DOI
  10.1080/14397595.2019.1703522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08649, KAKENHI-PROJECT-19K08645, KAKENHI-PROJECT-18K07958, KAKENHI-PROJECT-19H03698
[Journal Article] Clinical outcome of conservatively managed pancreatic intraductal papillary mucinous neoplasms with mural nodules and main duct dilation2020
- Author(s)
  Sakai Arata、Masuda Atsuhiro、Eguchi Takaaki、Anami Takahiro、Nishi Katsuhisa、Furumatsu Keisuke、Okabe Yoshihiro、Kakuyama Saori、Sato Yu、Nishioka Chiharu、Sanuki Tsuyoshi、Yagi Yosuke、Kobayashi Takashi、Shiomi Hideyuki、Kodama Yuzo
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 3 Pages: 285-292
- DOI
  10.1007/s00535-020-01739-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08444, KAKENHI-PROJECT-18K07266
[Journal Article] Efficacy and limitations of the histological diagnosis of type 1 autoimmune pancreatitis with endoscopic ultrasound-guided fine needle biopsy with large tissue amounts.2020
- Author(s)
  Notohara K, Kamisawa T, Kanno A, Naitoh I, Iwasaki E, Shimizu K, Kuraishi Y, Motoya M, Kodama Y, Kasashima S, Nishino T, Kubota K, Sakagami J, Ikeura T, Kawa S, Okazaki K.
- Journal Title
  
  Pancreatology.
  
  Volume: 5 Issue: 5 Pages: 834-843
- DOI
  10.1016/j.pan.2020.05.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03698
[Journal Article] Endoscopic ultrasound-guided gastrojejunostomy using fully covered metal stent combined with large-loop double-pigtail stent for malignant afferent loop syndrome.2019
- Author(s)
  Shiomi H, Kobayashi T, Sakai A, Shiomi Y, Masuda A, Bondoc EM, Kodama Y.
- Journal Title
  
  Endoscopy.
  
  Volume: 51(10) Issue: 10 Pages: E303-E304
- DOI
  10.1055/a-0916-8532
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08444
[Journal Article] Type 1 Autoimmune Pancreatitis with Imaging Appearance Similar to That of Malignant Cystic Tumor2019
- Author(s)
  Ezaki Takeshi、Masuda Atsuhiro、Shiomi Hideyuki、Nakagawa Takashi、Sofue Keitaro、Toyama Hirochika、Zen Yoh、Kodama Yuzo
- Journal Title
  
  Case Reports in Gastroenterology
  
  Volume: 13 Issue: 2 Pages: 265-270
- DOI
  10.1159/000500477
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02630, KAKENHI-PROJECT-19K08444
[Journal Article] Evaluation of efficacy of pancreatic juice cytology for risk classification according to international consensus guidelines in patients with intraductal papillary mucinous neoplasm; a retrospective study2019
- Author(s)
  Yamakawa Kohei、Masuda Atsuhiro、Nakagawa Takashi、Kobayashi Takashi、Tsujimae Masahiro、Ashina Shigeto、Yamada Yasutaka、Tanaka Takeshi、Tanaka Shunta、Nakano Ryota、Sato Yu、Ikegawa Takuya、Kurosawa Manabu、Fujigaki Seiji、Kutsumi Hiromu、Itoh Tomoo、Fukumoto Takumi、Kodama Yuzo
- Journal Title
  
  Pancreatology
  
  Volume: 19 Issue: 3 Pages: 424-428
- DOI
  10.1016/j.pan.2019.02.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07266, KAKENHI-PROJECT-19K08444
[Journal Article] An autopsy case of granulocyte colony-stimulating factor-producing pancreatic adenosquamous carcinoma.2019
- Author(s)
  Inomata N, Masuda A, Itani T, Hayashi M, Shimada Y, Adachi K, Hashimoto K, Tanaka Y, Tanaka A, Kobayashi T, Sakai A, Shiomi H, Kodama Y.
- Journal Title
  
  Clin J Gastroenterol.
  
  Volume: なし Issue: 3 Pages: 448-454
- DOI
  10.1007/s12328-019-01067-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08444
[Journal Article] Clinical outcomes of ampullary neoplasms in resected margin positive or uncertain cases after endoscopic papillectomy.2019
- Author(s)
  Sakai A, Tsujimae M, Masuda A, Iemoto T, Ashina S, Yamakawa K, Tanaka T, Tanaka S, Yamada Y, Nakano R, Sato Y, Kurosawa M, Ikegawa T, Fujigaki S, Kobayashi T, Shiomi H, Arisaka Y, Itoh T, Kodama Y.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 21;25(11) Issue: 11 Pages: 1387-1397
- DOI
  10.3748/wjg.v25.i11.1387
- NAID
  120006601542
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08444
[Journal Article] Significance of pancreatic calcification on preoperative computed tomography of intraductal papillary mucinous neoplasms2019
- Author(s)
  Tsujimae Masahiro、Masuda Atsuhiro、Shiomi Hideyuki、Kobayashi Takashi、Sakai Arata、Kutsumi Hiromu、Zen Yoh、Itoh Tomoo、Fukumoto Takumi、Kodama Yuzo
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 34 Issue: 9 Pages: 1648-1655
- DOI
  10.1111/jgh.14732
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07266, KAKENHI-PROJECT-19K08444
[Journal Article] Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis2019
- Author(s)
  Nishikawa Y、Kodama Y、Shiokawa M、Matsumori T、Marui S、Kuriyama K、Kuwada T、Sogabe Y、Kakiuchi N、Tomono T、Mima A、Morita T、Ueda T、Tsuda M、Yamauchi Y、Sakuma Y、Ota Y、Maruno T、Uza N、Uesugi M、Kageyama R、Chiba T、Seno H
- Journal Title
  
  Oncogene
  
  Volume: in press Issue: 22 Pages: 4283-4296
- DOI
  10.1038/s41388-019-0718-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06480, KAKENHI-PROJECT-17H06803, KAKENHI-PROJECT-16K09395, KAKENHI-PROJECT-19K22619, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-19J01318, KAKENHI-PROJECT-18K16149, KAKENHI-PLANNED-17H06408, KAKENHI-PROJECT-26220206
[Journal Article] Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone.2018
- Author(s)
  Perron A, Nishikawa Y, Iwata J, Shimojo H, Takaya J, Kobayashi K, Imayoshi I, Mbenza NM, Takenoya M, Kageyama R, Kodama Y, Uesugi M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 印刷中 Issue: 21 Pages: 8285-8294
- DOI
  10.1074/jbc.ra118.002316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09395, KAKENHI-PROJECT-17K19197, KAKENHI-PLANNED-17H06408, KAKENHI-PROJECT-17H06803, KAKENHI-PROJECT-26220206
[Journal Article] Pathogenicity of Immunoglobulin G in Patients with IgG4-related Disease.2016
- Author(s)
  Shiokawa M, Kodama Y, Kuriyama K, Yoshimura K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Minami R, Sakuma Y, Ota Y, Maruno T, Kurita A, Sawai Y, Tsuji Y, Uza N, Matsumura K, Watanabe T, Notohara K, Tsuruyama T, Seno H, Chiba T.
- Journal Title
  
  Gut
  
  Volume: 未定 Issue: 8 Pages: 3292-3301
- DOI
  10.1136/gutjnl-2015-310336
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15290, KAKENHI-PROJECT-26893123, KAKENHI-PROJECT-25461022, KAKENHI-PROJECT-26293173, KAKENHI-PROJECT-16K15427, KAKENHI-PROJECT-16K19339
[Journal Article] Diagnosis of autoimmune pancreatitis by endoscopic ultrasonography -guided fine-needle aspiration using a 22-gauge needle: a prospective multicenter study.2016
- Author(s)
  Kanno A, Masamune A, Fujishima F, Iwashita T, Kodama Y, Katanuma A, Ohara H, Kitano M, Inoue H, Itoi T, Mizuno N, Miyakawa H, Mikata R, Irisawa A, Sato S, Notohara K, Shimosegawa T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 84 Issue: 5 Pages: 797-797
- DOI
  10.1016/j.gie.2016.03.1511
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15290
[Journal Article] Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist2012
- Author(s)
  Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 109 Issue: 21 Pages: 1369-76
- DOI
  10.1073/pnas.1202464109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728, KAKENHI-PROJECT-23390322, KAKENHI-PROJECT-23659647
[Journal Article] Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression.2011
- Author(s)
  Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M
- Journal Title
  
  FASEB J
  
  Volume: 25 Issue: 4 Pages: 1133-44
- DOI
  10.1096/fj.10-168351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-22590728
[Journal Article] Non-alcoholic steatohepatitis-induced fibrosis : Toll-like receptors, reactive oxygen species and Jun N-terminal kinase2011
- Author(s)
  Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y
- Journal Title
  
  Hepatology Research
  
  Volume: 41 Issue: 7 Pages: 683-686
- DOI
  10.1111/j.1872-034x.2011.00814.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728, KAKENHI-PROJECT-23390322, KAKENHI-PROJECT-23659647
[Journal Article] Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase2011
- Author(s)
  Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 683-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728
[Journal Article] Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis2010
- Author(s)
  Inokuchi S, Aoyama T, Miura K, Osterreicher CH, Kodama Y, Miyai K, Akira S, Brenner DA, Seki E
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107 Issue: 2 Pages: 844-9
- DOI
  10.1073/pnas.0909781107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728
[Journal Article] Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice2010
- Author(s)
  Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Issue: 1 Pages: 323-34
- DOI
  10.1053/j.gastro.2010.03.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728
[Journal Article] Toll-like Receptor 9 Promotes Steatohepatitis via Induction of Interleukin-1beta in Mice.2010
- Author(s)
  Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 323-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728
[Journal Article] Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis2010
- Author(s)
  De Minicis S, Seki E, Paik YH, Osterreicher CH, Kodama Y, Kluwe J, Torozzi L, Miyai K, Benedetti A, Schwabe RF, Brenner DA
- Journal Title
  
  Hepatology
  
  Volume: 52 Issue: 4 Pages: 1420-30
- DOI
  10.1002/hep.23804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728
[Journal Article] Disruption of TAK1 in Hepatocytes Causes Hepatic Injury, Inflammation, Fibrosis and Carcinogenesis.2010
- Author(s)
  Inokuchi S, Aoyama T, Miura K, Osterreicher CH, Kodama Y, Miyai K, Akira s, Brenner DA, Seki E.
- Journal Title
  
  Proc Natl Acad Sci USA.
  
  Volume: 107 Pages: 844-849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590728
[Presentation] 膵癌のTLS(Tertiary lymphoid structure)を介した腫瘍免疫機構の解明2022
- Author(s)
  田中雄志、増田充弘、児玉裕三
- Organizer
  日本消化器病学会総会　シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] 腫瘍存在部位から見た膵癌の術前診断法の妥当性の検証と現状の課題2021
- Author(s)
  中野遼太、増田充弘、児玉裕三
- Organizer
  JDDW2021 シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] 背景膵のEUS所見と膵前癌病変の頻度との関連性　早期慢性膵炎所見によるハイリスク膵臓の予測2021
- Author(s)
  猪股典子、増田充弘、児玉裕三
- Organizer
  JDDW2021 シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] 当院における自己免疫性膵炎の長期予後と悪性腫瘍の発症および再燃リスク因子の検討2021
- Author(s)
  權田真知、増田充弘、児玉裕三
- Organizer
  第52回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-19H03698
[Presentation] 膵癌手術例における治療選択マーカーとしてのTLS(Tertiary lymphoid structure)の有用性2021
- Author(s)
  田中雄志、増田充弘、児玉裕三
- Organizer
  日本消化器病学会総会　シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] 膵切除検体を用いたEUSにおける早期慢性膵炎所見の妥当性の検証2021
- Author(s)
  猪股典子、増田充弘、児玉裕三
- Organizer
  日本消化器病学会総会　シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] A case of pancreatic cancer concomitant with IgG4-related disease in the pancreas and the stomach2021
- Author(s)
  Takashi Kobayashi, Masanori Gonda, Yuzo Kodama
- Organizer
  The 4th International symposium on IgG4-related diseases
- Data Source
  KAKENHI-PROJECT-19H03698
[Presentation] 膵頭部限局型自己免疫性膵炎の経過中に膵頭部に肺癌転移を来した一例2021
- Author(s)
  春山忠佑、小林隆、田中雄志、原田宜幸、三木美香、猪股典子、植村久尋、孝橋信哉、長尾佳映、阿部晶平、権田真知、増田重人、芦名茂人、辻前正弘、山川康平、山田恭孝、酒井新、増田充弘、児玉裕三
- Organizer
  第115回日本消化器病癌会近畿支部例会
- Data Source
  KAKENHI-PROJECT-19H03698
[Presentation] IPMN術後の残膵再発に関与する因子の検討　糖尿病の新規発症及び増悪の関連性2019
- Author(s)
  中野遼太、増田充弘、藤垣誠治、小林隆、酒井新、塩見英之、児玉裕三
- Organizer
  日本膵臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] 膵管内乳頭粘液産生腫瘍に対するERCP下膵液細胞診の役割　腫瘍の病理学的特徴との対比を含めて2019
- Author(s)
  山川康平、増田充弘、児玉裕三
- Organizer
  日本消化器内視鏡学会総会　シンポジウム
- Data Source
  KAKENHI-PROJECT-19K08444
[Presentation] Is Serum IgG in Patients with AIP Pathogenic?2017
- Author(s)
  Shiokawa Masahiro, Kodama Yuzo, Seno, Hiroshi, Chiba Tsutomu,
- Organizer
  International Symposium on IgG4-RD & Fibrosis
- Place of Presentation
  ハワイ
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Hes1 は膵癌マウスモデルにおいて膵発癌を抑制する2017
- Author(s)
  西川義浩、児玉裕三、桒田威、丸井彩子、曽我部裕子、森田敏広、垣内伸之、美馬淳志、松森友昭、友野輝子、上田樹、津田喬之、山内雄揮、佐久間洋二朗、栗山勝利、丸野貴久、塩川雅広、宇座徳光、妹尾浩
- Organizer
  第48回　日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09395
[Presentation] 膵癌形成における Hes1 の機能解析2017
- Author(s)
  西川義浩、児玉裕三、山内雄揮、津田喬之、妹尾浩
- Organizer
  第76回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09395
[Presentation] Biphasic Role of Hes1 in Pancreatic Development2016
- Author(s)
  Katsutoshi Kuriyama, Yuzo Kodama, Masahiro Shiokawa, Nobuyuki Kakiuchi, Tomoaki Matsumori, Atsushi Mima, Teruko Tomono, Yoshihiro Nishikawa, Motoyuki Tsuda, Tatsuki Ueda, Yuki Yamauchi, Yojiro Sakuma, Yuji Ota, Takahisa Maruno, Norimitsu Uza, Hiroshi Seno, Tsutomu Chiba
- Organizer
  American Gastroenterological Association, DDW 2016
- Place of Presentation
  San Diego
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09395
[Presentation] Hes1 plays an essential role in pancreatic carcinogenesis2016
- Author(s)
  Yoshihiro Nishikawa, Yuzo Kodama, Tsutomu Chiba, Hiroshi Seno
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K09395
[Presentation] 自己免疫性膵炎におけるIgGの病原性と抗原同定2016
- Author(s)
  塩川雅広、児玉裕三、垣内伸之、友野輝子、松森友昭、上田樹、津田喬之、西川義浩、山内雄揮、佐久間洋二朗、栗山勝利、宇座徳光、妹尾浩、千葉勉
- Organizer
  第33回日本胆膵病態・生理研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Pathogenic Role of IgG in Patients With IgG4-Related Disease on Neonatal Mice.2016
- Author(s)
  Shiokawa M, Kodama Y, Kuriyama K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Sakuma Y, Ota Y, Maruno T, Uza N, Seno H, Chiba T
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] IgG4関連疾患におけるIgGの病原性と標的抗原の解明2016
- Author(s)
  塩川　雅広、児玉　裕三、妹尾　浩、千葉　勉
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  新宿　京王プラザホテル
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Chemokine CXCL16 Plays a Critical Role in the Development of Severe Acute Pancreatitis2016
- Author(s)
  Sakuma Y, Kodama Y, Matsumori T, Tomono T, Kakiuchi N, Mima A, Yamauchi Y, Nishikawa Y, Tsuda M, Ueda T, Kuriyama K, Maruno T, Ota Y, Shiokawa M, Tsuji Y, Uza N, Watanabe T, Nakase H, Seno H, Chiba T
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] IgG4 関連疾患におけるIgG の病原性と標的抗原の解明2016
- Author(s)
  塩川雅広、児玉裕三、千葉勉
- Organizer
  第１０２回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Pathogenic Role of IgG in Patients with IgG4-related Disease on Neonatal Mice2016
- Author(s)
  Shiokawa M, Kodama Y, Kuriyama K, Yoshimura K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Minami R, Sakuma Y, Ota Y, Maruno T, Kurita A, Sawai Y, Tsuji Y, Uza N, Matsumura K, Watanabe T, Notohara K, Tsuruyama T, Seno H, Chiba T
- Organizer
  DDW
- Place of Presentation
  San　Diego
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] IgG4関連疾患におけるIgGの病原性と標的抗原の解明2016
- Author(s)
  塩川雅広、児玉裕三、千葉勉
- Organizer
  ＪＤＤＷ2016　第24回日本消化器関連学会週間
- Place of Presentation
  神戸
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K15290

1. Masuda Atsuhiro (60512530)

# of Collaborated Projects: 7 results

# of Collaborated Products: 18 results
2. Inoue Jun (50631561)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. Tobimatsu Kazutoshi (80766014)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 星奈美子 (40645214)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 塩川雅広 (50737880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. 今井俊夫 (50319662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. sakakura chouhei (10285257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKUDA Tsukasa (30291587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KODAMA Yuzou (80373687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. CHIBA Tsutomu (30188487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
11. Masamune Atsushi (90312579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小西英幸 (30295670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 濱田晋 (20451560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 長船健二 (80502947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 酒井新 (50792636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 妹尾浩 (90335266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 塩見英之 (40595485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小林隆 (90709669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 梶本武利 (00509953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 上田佳秀 (90378662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SEKIGUCHI Kiyotoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KURIYAMA Katsutoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. OSAWA Yosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. ITO Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. MORI Ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 祖父江慶太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 矢野嘉彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 清島満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 全陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 松本久子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 影山龍一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kodama Yuzo 児玉 裕三

KODAMA Yuzo 児玉 裕三

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消化器指定難病と免疫関連有害事象に共通する自己免疫機構の解明およびその臨床応用Principal Investigator

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自己抗原の同定に基づいた消化器系難病の病態解明と新しい診療体系の確立Principal Investigator

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Elucidation of pathophysiology and establishment of new diagnostic system for IgG4-related disease by autoantigen identificationPrincipal Investigator

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Development of novel therapy for pancreatic cancer targeting Notch/Hes1 signalingPrincipal Investigator

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The role of Notch/Hes1 signaling in the maintenance of homeostasis and carcinogenesis in pancreasPrincipal Investigator

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Kodama Yuzo 児玉裕三

KODAMA Yuzo 児玉裕三

[Book] 【診療ガイドライン改訂後の膵炎診療】EUS所見は何を見ているのか　組織像との対比など2022

[Book] 【膵臓症候群(第3版)-その他の膵臓疾患を含めて-】膵炎　1型自己免疫性膵炎(IgG4関連膵炎)2021

[Book] 【肝・胆道系症候群(第3版)-その他の肝・胆道系疾患を含めて-肝外胆道編】肝外胆管(胆管、胆嚢管、総胆管)　その他　Oddi括約筋機能不全2021