Ohno Kinji 大野欽司

… Alternative Names

OHNO Kinji 大野欽司

大野欽次オオノキンジ

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Researcher Number	80397455
Other IDs	https://orcid.org/0000-0002-1529-2750
Affiliation (Current)	2025: 名古屋学芸大学, 管理栄養学部, 教授
Affiliation (based on the past Project Information) *help	2024: 名古屋学芸大学, 管理栄養学部, 教授 2019 – 2023: 名古屋大学, 医学系研究科, 教授 2014 – 2017: 名古屋大学, 医学系研究科, 教授 2015: 名古屋大学, 大学院医学研究科, 教授 2015: 名古屋大学大学院医学系研究科, 神経遺伝情報学, 教授 … More 2014 – 2015: 名古屋大学, 大学院医学系研究科, 教授 2011 – 2015: 名古屋大学, 医学(系)研究科(研究院), 教授 2007 – 2012: Nagoya University, 大学院・医学系研究科, 教授 2010 – 2011: 名古屋大学, 医学系研究科, 教授 2006: Nagoya University, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授 2005: 名古屋大学, 大学院・医学系研究科, 教授 Less
Review Section/Research Field	Principal Investigator Neurology / Biological Sciences / Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 52:General internal medicine and related fields / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Pathological medical chemistry / Biological Sciences / Applied genomics Except Principal Investigator Orthopaedic surgery / Medium-sized Section 52:General internal medicine and related fields … More / Basic Section 56020:Orthopedics-related / Basic Section 52020:Neurology-related / High performance computing / Human genetics / Pediatrics / Food science / Psychiatric science / Applied health science / General pharmacology / Hygiene / Neurology Less
Keywords	Principal Investigator 先天性筋無力症候群 / 神経筋接合部 / アセチルコリン受容体 / 神経科学 / 遺伝子 / iPS細胞 / Wnt / LRP4 / LGR5 / RSPO2 … More / スプライシング異常 / 脳神経疾患 / 脳・神経 / 蛋白質 / 低周波変動超微弱磁場 / ミトコンドリア新生 / マイトファジー / 低周波変動超微弱磁場(ELF-EMF) / スプライシング / 神経筋信号伝達障害 / 遺伝子発現プロファイル / リボタグマウス / 廃用性筋萎縮 / サルコペニア / agrin / DOK7 / GFPT1 / Rspo2 / mRNA splicing / congenital myasthenic syndromes / mRNAスプライシング / MuSK / PolyA-seq / CLIP-seq / polyadenylation / RNA polymerase II / FUS / ColQ / hnRNP LL / hnRNP L / スプライシングトランス因子 / Collagen Q / 終板アセチルコリンエステラーゼ欠損症 / protein-anchoring therapy / siRNA設計アルゴリズム / スプライシングブランチポイント / 3'スプライスサイト / スプライシング遺伝子変異 / マイクロアレイ / ゲノム / タンニン酸 / least square linear fitting / mRNA secondary structure / prediction / siRNA / Pre-mRNAスプライシング機構 / スプライシング異常遺伝子変異 / 既認可薬によるスプライシング制御 / Exonic splicing enhancer破断遺伝子変異 / Intronic splicing silencer破断遺伝子変異 … More Except Principal Investigator 腸内細菌叢 / RUNX2 / 酸化ストレス / RNA / スプライシング / 高次脳機能障害 / 新生仔期免疫活性化 / 神経発達過程 / 神経回路 / 免疫 / 精神疾患 / 炎症性メディエーター / 周産期免疫活性化 / 短鎖脂肪酸 / ミクログリア / 患者死後脳 / 全ゲノム解析 / 22q11.2欠失 / 変形性関節症 / Drug repositioning / CD44断片化抑制 / Wnt/βカテニン抑制 / 多系統萎縮症 / 脚延長 / 骨芽細胞 / 骨髄幹細胞 / 培養骨芽細胞 / 脚延長術 / 培養骨髄細胞 / 臨床研究 / ヒト幹細胞 / 抽象化 / データベース / 高性能計算 / リピート不安定性 / RNA結合タンパク / RNA foci / GGCCTGリピート伸長 / SCA36 / 脊髄小脳失調10型 / スプライシング異常 / AUUCUリピート / RNA病態 / 非翻訳領域リピート伸長 / 脊髄小脳失調症10型 / 脊髄小脳失調症 / MMP-13 / 機械的刺激 / SOX9 / ATDC5 / TRPV4 / 家族内発症 / 遺伝子解析 / 潜因性West症候群 / LGI2 / 網羅的遺伝子解析 / West症候群 / 神経再支配 / drug repositioning / 神経筋接合部 / 再生医療 / 脂肪肝遺伝子 / 高脂肪食 / マウス / 肥満遺伝子 / 糖尿病遺伝子 / ﾊﾞｲｵｲﾝﾌｫﾏﾃｨｯｸｽ / バイオインフォマティックス / ゲノム医学 / 分子精神医学 / 統合失調症 / トランスクリプトーム解析 / シグナル伝達 / 水素 / 発現パターン / 大脳皮質 / mRNA / 神経発生 / プロファイリング解析 / スプライシング調節因子 / エクソンアレイ / 大脳皮質形成 / パーキンソン病 / ヒドロキシラジカル / 活性酸素 / 分子状水素 / 住環境 / 薬剤スクリーニング / Exonアレイ / 遺伝子スプライシング異常 / 筋強直性ジストロフィー1型(DM1) / myotonic dystrophy type 1(DM1) / 非翻訳リピート病 / DM1 / 優性遺伝性非翻訳領域リピート病 Less

Investigation of the molecular formations and the pathomechanisms of the neuromuscular junctionPrincipal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University of Arts and Sciences
  Nagoya University
Elucidation of molecular mechanisms and application to morbidities of mitochondrial neogenesis induced extremely low frequency weak electromagnetic fieldsPrincipal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Multi-layered study from the perspective of brain-immune system interactions to elucidate the pathophysiology of mental disorders.
- Principal Investigator
  
  Ozaki Norio
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Elucidation of molecular mechanisms of neuromuscular junction formations in physiology and pathologyPrincipal Investigator
- Principal Investigator
  
  Ohno Kinji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University
Impact of altered gut microbiota in multiple system atrophy
- Principal Investigator
  
  Maeda Tetsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Iwate Medical University
Elucidation of molecular mechanisms of defective neuromuscular signal transmission as a primary cause of sarcopeniaPrincipal Investigator
- Principal Investigator
  
  Ohno Kinji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Nagoya University
Development of a new therapeutic drug for osteoarthritis that has a cartilage-protecting effect by inhibiting Wnt/ADAM10
- Principal Investigator
  
  ISHIGURO Naoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
Elucidation of molecular architecture of neuromuscular junction and dissection of molecular pathomechanisms of congenital myasthenic syndromesPrincipal Investigator
- Principal Investigator
  
  Ohno Kinji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Transient receptor potential vanilloid 4 (TRPV4) plays a pivotal role in chondrogenic mechanotransduction in ATDC5 cells
- Principal Investigator
  
  Naoki Ishiguro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
神経変性疾患関連RNA結合タンパクFUSによる転写抑制機構解明Principal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Molecular dissection of LPR4, a molecule expressed at the neuromuscular junctionPrincipal Investigator
- Principal Investigator
  
  KINJI Ohno
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
Genetic analysis of Familial cryptogenic West syndrome.
- Principal Investigator
  
  ISHIHARA Naoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Fujita Health University
  Nagoya University
Runtime Systems with Abstraction of High-Performance Computing Resources
- Principal Investigator
  
  Kato Shinpei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  High performance computing
- Research Institution
  Nagoya University
Identification of diabetogenic and obesity genes by using nucleotides sequence variations between SM/J and A/J mice.
- Principal Investigator
  
  HORIO Fumihiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Nagoya University
Molecular bases and their regulations of mRNA aberrations in neuromuscular transmission defects and other muscular diseasesPrincipal Investigator
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Screening of a novel drug to activate the formation of neuromuscular junctions
- Principal Investigator
  
  HIRATA Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
Repeat instability and RNA-mediated disease mechanism of non-coding repeat expansion ataxias
- Principal Investigator
  
  Tohru Matsuura
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Jichi Medical University
The prospective study for the effects of culture-expanded bone marrow cells on the regeneration bone.
- Principal Investigator
  
  Ishiguro Naoki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
Transcriptome Analysis of Schizophrenia
- Principal Investigator
  
  OZAKI Norio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Nagoya University
Molecular mechanisms underlying the effects of molecular hydrogen on health promotion and disease control
- Principal Investigator
  
  ITO Masafumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  Institute of Applied Biochemistry
Analyzing neuronal development through deciphering splicing code
- Principal Investigator
  
  HAGIWARA Masatoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto University
  Tokyo Medical and Dental University
Analysis of mRNA metabolisms and therapeutic interventions for defects in neuromuscular signal transductionPrincipal Investigator
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
In silico解析とin vitro解析によるRNAスプライシング機構の研究Principal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
New approach for health maintenanceand disease control by modification of inhaled air composition
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Hygiene
- Research Institution
  Chubu University
Molecular bases and their regulations of mRNA aberrations in neuromuscular transmission defects and other muscular diseasesPrincipal Investigator
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Study on aberrant splicings in dominant non-coding repeat expansion disorders
- Principal Investigator
  
  MATSUURA Tohru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
ヒトゲノム配列解析によるRNAスプライシングとRNA代謝機構の研究Principal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
mRNAの1次塩基配列と2次構造予測に基づくsiRNA設計アルゴリズムの開発研究Principal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Nagoya University
神経節疾患の原因となるpre-mRNAスプライシング異常症の分子病態研究Principal Investigator
- Principal Investigator
  
  大野欽司
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Molecular pathomechanisms of congenital defects of neuromuscular transmissionPrincipal Investigator
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University

[Book] Clinical Neuroscience41巻2月号2023
- Author(s)
  大野欽司
- Total Pages
  144
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21H04815
[Book] 医学のあゆみ283巻10号2022
- Author(s)
  大野欽司
- Total Pages
  120
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-21H04815
[Book] 脳神経内科診断ハンドブック2021
- Author(s)
  大野欽司
- Total Pages
  604
- Publisher
  中外医学社
- ISBN
  9784498328785
- Data Source
  KAKENHI-PROJECT-21H04815
[Book] 「先天性筋無力症候群はどのような病気ですか」in『筋疾患』西野一三監修　神経内科Clinical Question and Pearls2018
- Author(s)
  大野欽司
- Publisher
  中外医学社
- ISBN
- Data Source
  KAKENHI-PROJECT-15H04840
[Book] 「先天性筋無力症候群の治療研究」in 『筋肉研究の最前線』武田伸一監修 CLINICAL CALCIUM 27(3): 97-104, 20172017
- Author(s)
  大野欽司
- Total Pages
  144
- Publisher
  医薬ジャーナル社
- ISBN
  9784753286232
- Data Source
  KAKENHI-PROJECT-15H04840
[Book] 「ドラッグリポジション戦略による神経筋骨格系病態治療（第28階日本末梢神経学会学術集会教育研修講演1）」in末梢神経 28(2)2017
- Author(s)
  大野欽司、大河原美静
- Total Pages
  400
- Publisher
  日本末梢神経学会事務局
- Data Source
  KAKENHI-PROJECT-15H04840
[Book] "Neurodegeneration-associated RNA-binding protein, FUS, regulates mRNA length" in Atlas of Science Ed. by Lynn C Yeoman. http://atlasofscience.org/neurodegeneration-associated-rna-binding-protein-fus-regulates-mrna-length/2016
- Author(s)
  Masuda A, Ohno K.
- Publisher
  AoS Nordic AB, Stockholm
- Data Source
  KAKENHI-PUBLICLY-25118508
[Book] "A hereditary mutation in Schwartz-Jampel syndrome " in Atlas of Science Ed. by Lynn C Yeoman. http://atlasofscience.org/a-hereditary-mutation-in-schwartz-jampel-syndrome/2015
- Author(s)
  Ito M, Ohno K.
- Publisher
  AoS Nordic AB, Stockholm
- Data Source
  KAKENHI-PROJECT-15H04840
[Book] "Collagen Q is a key player for developing rational therapy for congenital myasthenia and for dissecting the mechanisms of anti-MuSK myasthenia gravis" in J Mol Neurosci2014
- Author(s)
  Ohno K, Ito M, Kawakami Y.
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-25670164
[Book] "Molecular Genetics of Congenital Myasthenic Syndromes" in eLS2014
- Author(s)
  Ohno K, Ohkawara B, Ito M, Engel AG.
- Publisher
  John Wiley & Sons, Inc., Hoboken
- Data Source
  KAKENHI-PROJECT-24390221
[Book] Molecular Genetics of Congenital Myasthenic Syndromes. in eLS. DOI: 10.1002/9780470015902.a0024314)2014
- Author(s)
  Ohno K, Ohkawara B, Ito M, Engel AG.
- Publisher
  John Wiley & Sons, Inc., Hoboken, Chichester
- DOI
  10.1002/9780470015902.a0024314
- Data Source
  KAKENHI-PROJECT-24390221
[Book] "Molecular Genetics of Congenital Myasthenic Syndromes" in eLS2014
- Author(s)
  Ohno K, Ohkawara B, Ito M, Engel AG.
- Publisher
  John Wiley & Sons, Inc., Hoboken
- Data Source
  KAKENHI-PROJECT-25670164
[Book] "Collagen Q is a key player for developing rational therapy for congenital myasthenia and for dissecting the mechanisms of anti-MuSK myasthenia gravis" in J Mol Neurosci2014
- Author(s)
  Ohno K, Ito M, Kawakami Y.
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-24390221
[Book] Molecular Genetics of Congenital Myasthenic Syndromes2014
- Author(s)
  Ohno K, Ohkawara B, Ito M, Engel AG
- Publisher
  eLS. John Wiley & Sons, Inc., Hoboken(in press)
- Data Source
  KAKENHI-PROJECT-25670164
[Book] "Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis" in Chem Biol Interact 203(1)2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Krejci E, Engel AG.
- Total Pages
  376
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-24390221
[Book] Chapter 2: Intronic and exonic nucleotide variations that affect RNA splicing in humans. Genomics I - Humans, Animals and Plants.2013
- Author(s)
  Ohe K, Masuda A, Ohno K.
- Total Pages
  344
- Publisher
  iConcept Press, Hong Kong
- Data Source
  KAKENHI-PROJECT-24390221
[Book] Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis. Chem Biol Interact 203(1)2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Krejci E, Engel AG.
- Total Pages
  376
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-24390221
[Book] "Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis." in Chem Biol Interact 203(1)2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Krejci E, Engel AG.
- Total Pages
  376
- Publisher
  Elsevier, Amsterdam
- Data Source
  KAKENHI-PROJECT-25670164
[Book] Congenital Myasthenic Syndromes-Molecular Bases of Congenital Defects of Proteins at the Neuromuscular Junction-Myopathy2012
- Author(s)
  Ohno K, Ito M, Engel AG
- Publisher
  InTech, Rijeka(in press)(査読有)
- Data Source
  KAKENHI-PROJECT-21390266
[Book] Congenital myasthenic syndromes. Myasthenia gravis and myasthenic disorders 2nd ed.(Ed.by Engel AG)2012
- Author(s)
  Engel AG, Shen X-M, Ohno K, Sine SM
- Publisher
  Oxford University Press, New York(in press)
- Data Source
  KAKENHI-PROJECT-21390266
[Book] Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases. Oxid Med Cell Longev vol.2012. Article ID:3531522012
- Author(s)
  Ohno K, Ito M, Ichihara M, and Ito M.
- Publisher
  Hindawi Publishing Corporation, Cairo
- Data Source
  KAKENHI-PROJECT-24390221
[Book] Chapter 8 : Molecular defects of acetylcholine receptor subunits in congenital myasthenic syndromes. Pharmacology of Nicotinic Acetylcholine Receptors from the Basic and Therapeutic Perspectives2011
- Author(s)
  Ohno K, Engel AG
- Publisher
  Research Signpost, Kerala
- Data Source
  KAKENHI-PROJECT-21390266
[Book] RNA pathologies in neurological disorders. Neurochemical Mechanisms in Disease, Advances in Neurobiology(Ed by Abel Lajtha)2011
- Author(s)
  Ohno K, Masuda A
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-21390266
[Book] Chapter 8 : Molecular defects of acetylcholine receptor subunits in congenital myasthenic syndromes. Pharmacology of Nicotinic Acetylcholine Receptors from the Basic and Therapeutic Perspectives(Ed.By Hugo R.Arias)2011
- Author(s)
  Ohno K, Engel AG
- Publisher
  Research Signpost, Kerala
- Data Source
  KAKENHI-PROJECT-21390266
[Book] RNA pathologies in neurological disorders. Neurochemical Mechanisms in Disease, Advances in Neurobiology2011
- Author(s)
  Ohno K, Masuda A
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-21390266
[Book] Congenital Myasthenic Syndromes-Molecular Bases of Congenital Defects of Proteins at the NeuromuscularJunction- Myopathy
- Author(s)
  Ohno K, Ito M, Engel AG
- Publisher
  InTech, Rijeka(in press)
- Data Source
  KAKENHI-PROJECT-21390266
[Book] Congenital myasthenicsyndromes. Myasthenia gravis and myasthenic disorders 2nd ed. Ed. byEngel AG
- Author(s)
  Engel AG, Shen X-M, Ohno K, Sine SM
- Publisher
  Oxford University Press,New York(in press)
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Extremely Low Frequency, Extremely Low Magnetic Environment for depression: An open-label trial2024
- Author(s)
  Tachibana Masako、Inada Toshiya、Kimura Hiroki、Ito Mikako、Kuwatsuka Yachiyo、Kinoshita Fumie、Mori Daisuke、Ohno Kinji
- Journal Title
  
  Asian Journal of Psychiatry
  
  Volume: 96 Pages: 104036-104036
- DOI
  10.1016/j.ajp.2024.104036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18273, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21H02848
[Journal Article] Single-polyp metabolomics for coral health assessment2024
- Author(s)
  Iguchi Akira、Iijima Mariko、Mizusawa Nanami、Ohno Yoshikazu、Yasumoto Ko、Suzuki Atsushi、Suga Shunichi、Tanaka Ken、Zaitsu Kei
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 3369-3369
- DOI
  10.1038/s41598-024-53294-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00653, KAKENHI-PROJECT-21H04815
[Journal Article] Transcriptome profile of subsynaptic myonuclei at the neuromuscular junction in embryogenesis2024
- Author(s)
  Ohkawara B, Kurokawa M, Kanai A, Imamura K, Chen G, Zhang R, Masuda A, Higashi K, Mori H, Suzuki Y, Kurokawa K, Ohno K.
- Journal Title
  
  J Neurochem
  
  Volume: J Neurochem
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04815
[Journal Article] Dyssegmental dysplasia Rolland-Desbuquois type is caused by pathogenic variants in HSPG2 - a founder haplotype shared in five patients2024
- Author(s)
  Farshadyeganeh Paniz、Yamada Takahiro、Ohashi Hirofumi、Nishimura Gen、Fujita Hiroki、Oishi Yuriko、Nunode Misa、Ishikawa Shuku、Murotsuki Jun、Yamashita Yuri、Ikegawa Shiro、Ogi Tomoo、Arikawa-Hirasawa Eri、Ohno Kinji
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 69 Issue: 6 Pages: 235-244
- DOI
  10.1038/s10038-024-01229-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17810, KAKENHI-PROJECT-22K07543, KAKENHI-PROJECT-21H04815
[Journal Article] Calcitriol ameliorates motor deficits and prolongs survival of Chrne-deficient mouse, a model for congenital myasthenic syndrome, by inducing Rspo22024
- Author(s)
  Ohkawara Bisei、Tomita Hiroyuki、Inoue Taro、Zhang Shaochuan、Kanbara Shunsuke、Koshimizu Hiroyuki、Miyasaka Yuki、Takeda Jun-ichi、Nishiwaki Hiroshi、Nakashima Hiroaki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Ogi Tomoo、Ohno Tamio、Imagama Shiro、Ohno Kinji
- Journal Title
  
  Neurotherapeutics
  
  Volume: 21 Issue: 2 Pages: e00318-e00318
- DOI
  10.1016/j.neurot.2024.e00318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21H04815
[Journal Article] FexSplice: A LightGBM-Based Model for Predicting the Splicing Effect of a Single Nucleotide Variant Affecting the First Nucleotide G of an Exon2023
- Author(s)
  Joudaki Atefeh、Takeda Jun-ichi、Masuda Akio、Ode Rikumo、Fujiwara Koichi、Ohno Kinji
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 9 Pages: 1765-1765
- DOI
  10.3390/genes14091765
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K21309, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] Gut Microbiota Changes and Parkinson’s Disease: What Do We Know, Which Avenues Ahead2023
- Author(s)
  Hirayama M, Ohno K.
- Journal Title
  
  Gut Microbiota in Aging and Chronic Diseases
  
  Volume: - Pages: 257-278
- DOI
  10.1007/978-3-031-14023-5_13
- ISBN
  9783031140228, 9783031140235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04815
[Journal Article] Microglia Enable Cross-Modal Plasticity by Removing Inhibitory Synapses2023
- Author(s)
  Hashimoto A, Kawamura N, Tarusawa E, Takeda I, Aoyama Y, Ohno N, Inoue M, Kagamiuchi M, Kato D, Matsumoto M, Hasegawa Y, Nabekura J, Schaefer A, Moorhouse AJ, Yagi T, Wake H
- Journal Title
  
  Cell Reports
  
  Volume: - Issue: 5 Pages: 112383-112383
- DOI
  10.1016/j.celrep.2023.112383
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0170, KAKENHI-PLANNED-20H05899, KAKENHI-PUBLICLY-21H05688, KAKENHI-PROJECT-21H02662, KAKENHI-PROJECT-20K06873, KAKENHI-PROJECT-20K20379, KAKENHI-PROJECT-23K06825, KAKENHI-PROJECT-22K15202, KAKENHI-PROJECT-18H04016, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H04815
[Journal Article] Extremely low-frequency electromagnetic field induces acetylation of heat shock proteins and enhances protein folding2023
- Author(s)
  Huang Zhizhou、Ito Mikako、Zhang Shaochuan、Toda Takuro、Takeda Jun-ichi、Ogi Tomoo、Ohno Kinji
- Journal Title
  
  Ecotoxicology and Environmental Safety
  
  Volume: 264 Pages: 115482-115482
- DOI
  10.1016/j.ecoenv.2023.115482
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18273, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] Machine learning models predict delayed hyponatremia post-transsphenoidal surgery using clinically available features2023
- Author(s)
  Fuse Y, Nishiwaki H, Imaizumi T, Nagata Y, Ohno K, Saito R.
- Journal Title
  
  Pituitary
  
  Volume: - Issue: 2 Pages: 237-249
- DOI
  10.1007/s11102-023-01311-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-22K17343
[Journal Article] The On/off History of Hydrogen in Medicine: Will the interest persist this time around?2023
- Author(s)
  LeBaron TW, Ohno K, Hancock JT.
- Journal Title
  
  Oxygen
  
  Volume: 3 Issue: 1 Pages: 143-162
- DOI
  10.3390/oxygen3010011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Journal Article] Neural Isoforms of Agrin Are Generated by Reduced PTBP1-RNA Interaction Network Spanning the Neuron-Specific Splicing Regions in AGRN2023
- Author(s)
  Bushra Samira、Lin Ying-Ni、Joudaki Atefeh、Ito Mikako、Ohkawara Bisei、Ohno Kinji、Masuda Akio
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 8 Pages: 7420-7420
- DOI
  10.3390/ijms24087420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-23K21309, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction2023
- Author(s)
  Farshadyeganeh Paniz、Nazim Mohammad、Zhang Ruchen、Ohkawara Bisei、Nakajima Kazuki、Rahman Mohammad Alinoor、Nasrin Farhana、Ito Mikako、Takeda Jun-ichi、Ohe Kenji、Miyasaka Yuki、Ohno Tamio、Masuda Akio、Ohno Kinji
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 10 Pages: 107746-107746
- DOI
  10.1016/j.isci.2023.107746
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21K08266, KAKENHI-PROJECT-23K21309, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K27485
[Journal Article] Clinical and Pathologic Features of Congenital Myasthenic Syndromes Caused by 35 Genes?A Comprehensive Review2023
- Author(s)
  Ohno Kinji、Ohkawara Bisei、Shen Xin-Ming、Selcen Duygu、Engel Andrew G.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3730-3730
- DOI
  10.3390/ijms24043730
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Impaired gating of γ- and ε-AChR respectively causes Escobar syndrome and fast channel myasthenia2023
- Author(s)
  Shen XM, Nakata T, Mizuno S, Imoto I, Selcen D, Ohno K, Engel AG.
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: - Issue: 5 Pages: 732-743
- DOI
  10.1002/acn3.51756
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-23K27485
[Journal Article] Evaluation of Human-Induced Pluripotent Stem Cells Derived from a Patient with Schwartz Jampel Syndrome Revealed Distinct Hyperexcitability in the Skeletal Muscles2023
- Author(s)
  Yamashita Y, Nakada S, Nakamura K, Sakurai H, Ohno K, Goto T, Mabuchi Y, Akazawa C, Hattori N, Arikawa-Hirasawa E.
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 3 Pages: 814-814
- DOI
  10.3390/biomedicines11030814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-22K17810, KAKENHI-PROJECT-22K07543, KAKENHI-PROJECT-21K17589
[Journal Article] Activated FGFR3 suppresses bone regeneration and bone mineralization in an ovariectomized mouse model2023
- Author(s)
  Kawashima Itaru、Matsushita Masaki、Mishima Kenichi、Kamiya Yasunari、Osawa Yusuke、Ohkawara Bisei、Ohno Kinji、Kitoh Hiroshi、Imagama Shiro
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 24 Issue: 1 Pages: 200-200
- DOI
  10.1186/s12891-023-06318-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-20K09477, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-21K06392
[Journal Article] Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson’s disease2022
- Author(s)
  Nishiwaki Hiroshi、Ito Mikako、Hamaguchi Tomonari、Maeda Tetsuya、Kashihara Kenichi、Tsuboi Yoshio、Ueyama Jun、Yoshida Takumi、Hanada Hiroyuki、Takeuchi Ichiro、Katsuno Masahisa、Hirayama Masaaki、Ohno Kinji
- Journal Title
  
  npj Parkinson's Disease
  
  Volume: 8 Issue: 1 Pages: 65-65
- DOI
  10.1038/s41531-022-00328-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-22K15394, KAKENHI-PROJECT-22K17343, KAKENHI-PROJECT-21H04815
[Journal Article] Meclozine ameliorates bone mineralization and growth plate structure in a mouse model of X-linked hypophosphatemia2022
- Author(s)
  Kamiya Yasunari、Matsushita Masaki、Mishima Kenichi、Ohkawara Bisei、Michigami Toshimi、Imagama Shiro、Ohno Kinji、Kitoh Hiroshi
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 25 Issue: 1 Pages: 39-39
- DOI
  10.3892/etm.2022.11738
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-20K09477, KAKENHI-PROJECT-22K09398, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H03063
[Journal Article] A mutation in DOK7 in congenital myasthenic syndrome forms aggresome in cultured cells, and reduces DOK7 expression and MuSK phosphorylation in patient-derived iPS cells2022
- Author(s)
  Zhang Shaochuan、Ohkawara Bisei、Ito Mikako、Huang Zhizhou、Zhao Fei、Nakata Tomohiko、Takeuchi Tomoya、Sakurai Hidetoshi、Komaki Hirofumi、Kamon Masayoshi、Araki Toshiyuki、Ohno Kinji
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 32 Issue: 9 Pages: 1511-1523
- DOI
  10.1093/hmg/ddac306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-19K09565, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-23K27485
[Journal Article] Electrolyzed Reduced Water: Review I. Molecular hydrogen is the Exclusive Agent Responsible for the Therapeutic Effects2022
- Author(s)
  LeBaron TW, Sharpe R, Ohno K.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 23 Pages: 14750-14750
- DOI
  10.3390/ijms232314750
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Journal Article] Efficacy of soluble lansoprazole-impregnated beta-tricalcium phosphate for bone regeneration2022
- Author(s)
  Mishima Kenichi、Okabe Yuka Tsukagoshi、Mizuno Masaaki、Ohno Kinji、Kitoh Hiroshi、Imagama Shiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-022-25184-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09573, KAKENHI-PROJECT-22K09304, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-18K16656
[Journal Article] Promethazine downregulates Wnt/β-catenin signaling and increases biomechanical forces of injured Achilles tendon in early stage of healing2022
- Author(s)
  Sakaguchi T, Miyamoto K, Ohkawara B, Kisimoto Y, Ishizuka S, Hiraiwa H, Imagama S, Ishiguro N, Ohno K.
- Journal Title
  
  Am J Sport Med
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22802
[Journal Article] Electrolyzed Reduced Water: Review II. Safety Concerns and Effectiveness as a Source of Hydrogen Water2022
- Author(s)
  LeBaron TW, Sharpe R, Ohno K.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 23 Pages: 14508-14508
- DOI
  10.3390/ijms232314508
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Journal Article] Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase2022
- Author(s)
  Koike Hiroshi、Nishida Yoshihiro、Shinomura Tamayuki、Ohkawara Bisei、Ohno Kinji、Zhuo Lisheng、Kimata Koji、Ushida Takahiro、Imagama Shiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 8 Pages: 4089-4089
- DOI
  10.3390/ijms23084089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-20K18060, KAKENHI-PROJECT-22K16740, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Gut microbiota in dementia with Lewy bodies2022
- Author(s)
  Nishiwaki Hiroshi、Ueyama Jun、Kashihara Kenichi、Ito Mikako、Hamaguchi Tomonari、Maeda Tetsuya、Tsuboi Yoshio、Katsuno Masahisa、Hirayama Masaaki、Ohno Kinji
- Journal Title
  
  npj Parkinson's Disease
  
  Volume: 8 Issue: 1 Pages: 169-169
- DOI
  10.1038/s41531-022-00428-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-22K15394, KAKENHI-PROJECT-22K17343, KAKENHI-PROJECT-21H04815
[Journal Article] Screening of signaling pathways for agrin-induced AChR clustering in C2C12 myotubes2022
- Author(s)
  Noto K, Ohkawara B, Ishii H, Ito M, Masuda A, Hirata H, Ohno K.
- Journal Title
  
  Genes Cells
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22802
[Journal Article] Meclozine ameliorates skeletal muscle pathology and increases muscle forces in mdx mice2022
- Author(s)
  Kawamura Yusuke、Hida Tetsuro、Ohkawara Bisei、Matsushita Masaki、Kobayashi Takeshi、Ishizuka Shinya、Hiraiwa Hideki、Tanaka Satoshi、Tsushima Mikito、Nakashima Hiroaki、Ito Kenyu、Imagama Shiro、Ito Mikako、Masuda Akio、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 592 Pages: 87-92
- DOI
  10.1016/j.bbrc.2022.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21K06149, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K21309
[Journal Article] Reply to the Letter to the Editor “The microbiota in Parkinson's disease: ranking the risk of heart disease”2022
- Author(s)
  Hirayama M, Ohno K.
- Journal Title
  
  Ann Nutr Metab
  
  Volume: 78 Issue: 2 Pages: 119-120
- DOI
  10.1159/000521993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04815
[Journal Article] Promethazine Downregulates Wnt/β-Catenin Signaling and Increases the Biomechanical Forces of the Injured Achilles Tendon in the Early Stage of Healing2022
- Author(s)
  Sakaguchi Takefumi、Ohkawara Bisei、Kishimoto Yasuzumi、Miyamoto Kentaro、Ishizuka Shinya、Hiraiwa Hideki、Ishiguro Naoki、Imagama Shiro、Ohno Kinji
- Journal Title
  
  The American Journal of Sports Medicine
  
  Volume: 50 Issue: 5 Pages: 1317-1327
- DOI
  10.1177/03635465221077116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-21H04815
[Journal Article] Meclozine Attenuates the MARK Pathway in Mammalian Chondrocytes and Ameliorates FGF2-Induced Bone Hyperossification in Larval Zebrafish2022
- Author(s)
  Takemoto Genta、Matsushita Masaki、Okamoto Takaaki、Ito Toshinari、Matsuura Yuki、Takashima Chieko、Chen-Yoshikawa Toyofumi Fengshi、Ebi Hiromichi、Imagama Shiro、Kitoh Hiroshi、Ohno Kinji、Hosono Yasuyuki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 694018-694018
- DOI
  10.3389/fcell.2021.694018
- NAID
  120007190703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21H03063, KAKENHI-PROJECT-19K09646, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response2022
- Author(s)
  Hasegawa Tomoya、Ito Mikako、Hasegawa Satoru、Teranishi Masaki、Takeda Koki、Negishi Shuto、Nishiwaki Hiroshi、Takeda Jun-ichi、LeBaron Tyler W.、Ohno Kinji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 5 Pages: 2888-2888
- DOI
  10.3390/ijms23052888
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21H04815
[Journal Article] Examination of Abnormal Alpha-synuclein Aggregates in the Enteric Neural Plexus in Patients with Ulcerative Colitis2022
- Author(s)
  Gibo Noriaki、Hamaguchi Tomonari、Miki Yasuo、Yamamura Takeshi、Nakaguro Masato、Ito Mikako、Nakamuara Masanao、Kawashima Hiroki、Hirayama Masaaki、Hirooka Yoshiki、Wakabayashi Koichi、Ohno Kinji
- Journal Title
  
  Journal of Gastrointestinal and Liver Diseases
  
  Volume: 31 Issue: 3 Pages: 290-300
- DOI
  10.15403/jgld-4313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-22K15394, KAKENHI-PROJECT-21H04815
[Journal Article] Extremely low-frequency pulses of faint magnetic field induce mitophagy to rejuvenate mitochondria2022
- Author(s)
  Toda Takuro、Ito Mikako、Takeda Jun-ichi、Masuda Akio、Mino Hiroyuki、Hattori Nobutaka、Mohri Kaneo、Ohno Kinji
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 453-453
- DOI
  10.1038/s42003-022-03389-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-22K19269, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-23K21309
[Journal Article] Efficacy of auranofin as an inhibitor of desmoid progression2022
- Author(s)
  Ito Kan、Nishida Yoshihiro、Hamada Shunsuke、Shimizu Koki、Sakai Tomohisa、Ohkawara Bisei、Alman Benjamin A.、Enomoto Atsushi、Ikuta Kunihiro、Koike Hiroshi、Zhang Jiarui、Ohno Kinji、Imagama Shiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 11918-11918
- DOI
  10.1038/s41598-022-15756-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09321, KAKENHI-PROJECT-19K16769, KAKENHI-PROJECT-20K18060, KAKENHI-PROJECT-22K16740, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-20K16328, KAKENHI-PROJECT-17H01585
[Journal Article] Extremely low-frequency pulses of faint magnetic field induce mitophagy to rejuvenate mitochondria2022
- Author(s)
  Toda T, Ito M Takeda J, Masuda A, Mino H, Hattori N, Mohri K, Ohno K
- Journal Title
  
  Commun Biol
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802
[Journal Article] Effects of Pesticide Intake on Gut Microbiota and Metabolites in Healthy Adults2022
- Author(s)
  Ueyama Jun、Hayashi Mai、Hirayama Masaaki、Nishiwaki Hiroshi、Ito Mikako、Saito Isao、Tsuboi Yoshio、Isobe Tomohiko、Ohno Kinji
- Journal Title
  
  International Journal of Environmental Research and Public Health
  
  Volume: 20 Issue: 1 Pages: 213-213
- DOI
  10.3390/ijerph20010213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20K10450, KAKENHI-PROJECT-23K06412
[Journal Article] Altered gut microbiota in Parkinson's disease patients with motor complications2022
- Author(s)
  Takahashi Kai、Nishiwaki Hiroshi、Ito Mikako、Iwaoka Kazuhiro、Takahashi Kenta、Suzuki Yoshio、Taguchi Keita、Yamahara Kanako、Tsuboi Yoshio、Kashihara Kenichi、Hirayama Masaaki、Ohno Kinji、Maeda Tetsuya
- Journal Title
  
  Parkinsonism & Related Disorders
  
  Volume: 95 Pages: 11-17
- DOI
  10.1016/j.parkreldis.2021.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08001, KAKENHI-PROJECT-20K06925
[Journal Article] Rapidly Growing Protein-Centric Technologies to Extensively Identify Protein?RNA Interactions: Application to the Analysis of Co-Transcriptional RNA Processing2021
- Author(s)
  Masuda Akio、Kawachi Toshihiko、Ohno Kinji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 10 Pages: 5312-5312
- DOI
  10.3390/ijms22105312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Zonisamide upregulates neuregulin-1 expression and enhances acetylcholine receptor clustering at the in vitro neuromuscular junction2021
- Author(s)
  Inoue Taro、Ohkawara Bisei、Bushra Samira、Kanbara Shunsuke、Nakashima Hiroaki、Koshimizu Hiroyuki、Tomita Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Ohno Kinji
- Journal Title
  
  Neuropharmacology
  
  Volume: 195 Pages: 108637-108637
- DOI
  10.1016/j.neuropharm.2021.108637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Secreted Signaling Molecules at the Neuromuscular Junction in Physiology and Pathology2021
- Author(s)
  Ohkawara Bisei、Ito Mikako、Ohno Kinji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 5 Pages: 2455-2455
- DOI
  10.3390/ijms22052455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20H03561
[Journal Article] Efficacy of salbutamol monotherapy in slow‐channel congenital myasthenic syndrome caused by a novel mutation in CHRND2021
- Author(s)
  Tawara Nozomu、Yamashita Satoshi、Takamatsu Koutaro、Yamasaki Yoshimune、Mukaino Akihiro、Nakane Shunya、Farshadyeganeh Paniz、Ohno Kinji、Ando Yukio
- Journal Title
  
  Muscle & Nerve
  
  Volume: 63 Issue: 4
- DOI
  10.1002/mus.27166
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07870, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19H03565, KAKENHI-PROJECT-20H03561
[Journal Article] Hierarchical non-negative matrix factorization using clinical information for microbial communities2021
- Author(s)
  Abe Ko、Hirayama Masaaki、Ohno Kinji、Shimamura Teppei
- Journal Title
  
  BMC Genomics
  
  Volume: 22 Issue: 1 Pages: 104-104
- DOI
  10.1186/s12864-021-07401-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-20H04281
[Journal Article] Screening of signaling pathways for agrin-induced AChR clustering in C2C12 myotubes2021
- Author(s)
  Noto K, Ohkawara B, Ishii H, Ito M, Masuda A, Hirata H, Ohno K.
- Journal Title
  
  Genes Cells
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03561
[Journal Article] Regulated splicing of large exons is linked to phase‐separation of vertebrate transcription factors2021
- Author(s)
  Kawachi Toshihiko、Masuda Akio、Yamashita Yoshihiro、Takeda Jun‐ichi、Ohkawara Bisei、Ito Mikako、Ohno Kinji
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 22
- DOI
  10.15252/embj.2020107485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Intestinal Collinsella may mitigate infection and exacerbation of COVID-19 by producing ursodeoxycholate2021
- Author(s)
  Hirayama Masaaki、Nishiwaki Hiroshi、Hamaguchi Tomonari、Ito Mikako、Ueyama Jun、Maeda Tetsuya、Kashihara Kenichi、Tsuboi Yoshio、Ohno Kinji
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 11 Pages: 0260451-0260451
- DOI
  10.1371/journal.pone.0260451
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08001, KAKENHI-PROJECT-20K06925
[Journal Article] IntSplice2: Prediction of the Splicing Effects of Intronic Single-Nucleotide Variants Using LightGBM Modeling2021
- Author(s)
  Takeda Jun-ichi、Fukami Sae、Tamura Akira、Shibata Akihide、Ohno Kinji
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 12 Pages: 701076-701076
- DOI
  10.3389/fgene.2021.701076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561
[Journal Article] Congenital myasthenic syndrome?associated agrin variants affect clustering of acetylcholine receptors in a domain-specific manner2020
- Author(s)
  Ohkawara Bisei、Shen XinMing、Selcen Duygu、Nazim Mohammad、Bril Vera、Tarnopolsky Mark A.、Brady Lauren、Fukami Sae、Amato Anthony A.、Yis Uluc、Ohno Kinji、Engel Andrew G.
- Journal Title
  
  JCI Insight
  
  Volume: 5 Issue: 7
- DOI
  10.1172/jci.insight.132023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20H03561
[Journal Article] tRIP-seq Reveals Repression of Premature Polyadenylation by Co-Transcriptional FUS-U1 snRNP Assembly2020
- Author(s)
  Akio Masuda, Toshihiko Kawachi, Jun-Ichi Takeda, Bisei Ohkawara, Mikako Ito, Kinji Ohno
- Journal Title
  
  EMBO Rep.
  
  Volume: - Issue: 5
- DOI
  10.15252/embr.201949890
- NAID
  120006884959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-18K14684
[Journal Article] Identification of Qk as a Glial Precursor Cell Marker that Governs the Fate Specification of Neural Stem Cells to a Glial Cell Lineage2020
- Author(s)
  Takeuchi Akihide、Takahashi Yuji、Iida Kei、Hosokawa Motoyasu、Irie Koichiro、Ito Mikako、Brown J.B.、Ohno Kinji、Nakashima Kinichi、Hagiwara Masatoshi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 15 Issue: 4 Pages: 883-897
- DOI
  10.1016/j.stemcr.2020.08.010
- NAID
  120006888017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06907, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-15H05721, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-17K07094
[Journal Article] Extended Neviaser portal approachを用いた上腕骨近位端髄内釘固定の術後成績とMRI所見2020
- Author(s)
  羽賀貴博, 井戸田大, 小早川晃範, 坂口健史, 大羽宏樹, 川村佑介, 宮本健太郎, 山下暁士, 石塚真哉, 平岩秀樹, 大野洋平, 山本和樹, 熊澤雅樹, 良田洋昇, 片岡祐司
- Journal Title
  
  JOSKAS
  
  Volume: 45(2) Pages: 324-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03779
[Journal Article] Zonisamide ameliorates progression of cervical spondylotic myelopathy in a rat model2020
- Author(s)
  Kanbara Shunsuke、Ohkawara Bisei、Nakashima Hiroaki、Ohta Kyotaro、Koshimizu Hiroyuki、Inoue Taro、Tomita Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Ohno Kinji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13138-13138
- DOI
  10.1038/s41598-020-70068-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-20H03561
[Journal Article] Short-Chain Fatty Acid-Producing Gut Microbiota Is Decreased in Parkinson’s Disease but Not in Rapid-Eye-Movement Sleep Behavior Disorder2020
- Author(s)
  Nishiwaki Hiroshi、Hamaguchi Tomonari、Ito Mikako、Ishida Tomohiro、Maeda Tetsuya、Kashihara Kenichi、Tsuboi Yoshio、Ueyama Jun、Shimamura Teppei、Mori Hiroshi、Kurokawa Ken、Katsuno Masahisa、Hirayama Masaaki、Ohno Kinji
- Journal Title
  
  mSystems
  
  Volume: 5 Issue: 6
- DOI
  10.1128/msystems.00797-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08001, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-17K07094
[Journal Article] InMeRF: prediction of pathogenicity of missense variants by individual modeling for each amino acid substitution2020
- Author(s)
  Takeda Jun-ichi、Nanatsue Kentaro、Yamagishi Ryosuke、Ito Mikako、Haga Nobuhiko、Hirata Hiromi、Ogi Tomoo、Ohno Kinji
- Journal Title
  
  NAR Genomics and Bioinformatics
  
  Volume: 2 Issue: 2 Pages: 1-11
- DOI
  10.1093/nargab/lqaa038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19H03329, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-18K14684
[Journal Article] Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model2020
- Author(s)
  Koshimizu Hiroyuki、Ohkawara Bisei、Nakashima Hiroaki、Ota Kyotaro、Kanbara Shunsuke、Inoue Taro、Tomita Hiroyuki、Sayo Akira、Kiryu-Seo Sumiko、Konishi Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Kiyama Hiroshi、Ohno Kinji
- Journal Title
  
  Life Sciences
  
  Volume: 263 Pages: 118577-118577
- DOI
  10.1016/j.lfs.2020.118577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19K24067, KAKENHI-PROJECT-18H02524, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-17K07094
[Journal Article] Author Correction: Mianserin suppresses R-spondin 2-induced activation of Wnt/β-catenin signaling in chondrocytes and prevents cartilage degradation in a rat model of osteoarthritis2020
- Author(s)
  Okura Toshiaki、Ohkawara Bisei、Takegami Yasuhiko、Ito Mikako、Masuda Akio、Seki Taisuke、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 2995-2995
- DOI
  10.1038/s41598-020-60112-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-18K09062
[Journal Article] Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair2020
- Author(s)
  Nakazawa Y, Hara Y, Oka Y, Komine O, van den Heuvel D, Guo C, Daigaku Y, Isono M, He Y, Shimada M, Kato K, Jia N, Hashimoto S, Kotani Y, Miyoshi Y, Tanaka M, Sobue A, Mitsutake N, Suganami T, Masuda A, Ohno K, Nakada S, Mashimo T, Yamanaka K, Luijsterburg MS, Ogi T
- Journal Title
  
  Cell
  
  Volume: 19 Issue: 6 Pages: 1228-1244
- DOI
  10.1016/j.cell.2020.02.010
- NAID
  120006871293
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K08508, KAKENHI-PROJECT-18K11639, KAKENHI-PROJECT-18K19585, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17H01877, KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-16H06151, KAKENHI-PROJECT-17K12821, KAKENHI-PROJECT-19K21221
[Journal Article] Desloratadine inhibits heterotopic ossification by suppression of BMP2‐Smad1/5/8 signaling2020
- Author(s)
  Kusano Taiki、Nakatani Masashi、Ishiguro Naoki、Ohno Kinji、Yamamoto Naoki、Morita Mitsuhiro、Yamada Harumoto、Uezumi Akiyoshi、Tsuchida Kunihiro
- Journal Title
  
  Journal of Orthopaedic Research
  
  Volume: in press Issue: 6 Pages: 11-11
- DOI
  10.1002/jor.24625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-17K01485, KAKENHI-PROJECT-19K18497, KAKENHI-PROJECT-20K11247, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-18K09122, KAKENHI-PROJECT-19K22802
[Journal Article] Meta‐Analysis of Gut Dysbiosis in Parkinson's Disease2020
- Author(s)
  Nishiwaki Hiroshi、Ito Mikako、Ishida Tomohiro、Hamaguchi Tomonari、Maeda Tetsuya、Kashihara Kenichi、Tsuboi Yoshio、Ueyama Jun、Shimamura Teppei、Mori Hiroshi、Kurokawa Ken、Katsuno Masahisa、Hirayama Masaaki、Ohno Kinji
- Journal Title
  
  Movement Disorders
  
  Volume: 35 Issue: 9 Pages: 1626-1635
- DOI
  10.1002/mds.28119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08001, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-17K07094
[Journal Article] Congenital myasthenic syndrome-associated agrin variants affect clustering of acetylcholine receptors in a domain-specific manner2020
- Author(s)
  Ohkawara B, Shen X-M, Selcen D, Nazim M, Bril V, Tarnopolsky MA, Brady L, Fukami S, Amato AA, Yis U, Ohno K, Engel AG
- Journal Title
  
  JCI Insight
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22802
[Journal Article] Gene Expression Profile at the Motor Endplate of the Neuromuscular Junction of Fast-Twitch Muscle2020
- Author(s)
  Huang Kun、Li Jin、Ito Mikako、Takeda Jun-Ichi、Ohkawara Bisei、Ogi Tomoo、Masuda Akio、Ohno Kinji
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 13 Pages: 154-154
- DOI
  10.3389/fnmol.2020.00154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-18K14684
[Journal Article] Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells.2020
- Author(s)
  Huang K, Masuda A, Chen G, Bushra S, Kamon M, Araki T, Kinoshita M, Ohkawara B, Ito M, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 2558-2558
- DOI
  10.1038/s41598-020-59517-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-19K09565, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-17K07094
[Journal Article] CTGF/CCN2 facilitates LRP4‐mediated formation of the embryonic neuromuscular junction2020
- Author(s)
  Ohkawara Bisei、Kobayakawa Akinori、Kanbara Shunsuke、Hattori Takako、Kubota Satoshi、Ito Mikako、Masuda Akio、Takigawa Masaharu、Lyons Karen M、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  EMBO reports
  
  Volume: 21 Issue: 8
- DOI
  10.15252/embr.201948462
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K10150, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-19H03817, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-19K22716
[Journal Article] MYRF is associated with encephalopathy with reversible myelin vacuolization2018
- Author(s)
  Kurahashi Hirokazu、Azuma Yoshiteru、Masuda Akio、Okuno Tatsuya、Nakahara Eri、Imamura Takuji、Saitoh Makiko、Mizuguchi Masashi、Shimizu Toshiaki、Ohno Kinji、Okumura Akihisa
- Journal Title
  
  Annals of Neurology
  
  Volume: 83 Issue: 1 Pages: 98-106
- DOI
  10.1002/ana.25125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10086, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K07890, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04872
[Journal Article] Loss of Sfpq causes long-gene transcriptopathy in the brain2018
- Author(s)
  Takeuchi A, Iida K, Tsubota T, Hosokawa M, Denawa M, Ninomiya K, Ito M, Kimura H, Abe T, Kiyonari H, Ohno K, Hagiwara M.
- Journal Title
  
  Cell Rep
  
  Volume: -
- NAID
  120006463742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04840
[Journal Article] Rules and tools to predict the splicing effects of exonic and intronic mutations2018
- Author(s)
  Ohno K, Takeda J, Masuda A.
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1002/wrna.1451
- NAID
  120006473502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters2018
- Author(s)
  Ito Kenyu、Ohkawara Bisei、Yagi Hideki、Nakashima Hiroaki、Tsushima Mikito、Ota Kyotaro、Konishi Hiroyuki、Masuda Akio、Imagama Shiro、Kiyama Hiroshi、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Sceintific Reports
  
  Volume: 8 Issue: 1 Pages: 434-434
- DOI
  10.1038/s41598-017-18753-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-17K16688, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-15K06755
[Journal Article] Loss of Sfpq causes long-gene transcriptopathy in the brain.2018
- Author(s)
  Takeuchi A, Iida K, Tsubota T, Hosokawa M, Denawa M, Brown JB, Ninomiya K, Ito M, Kimura H, Abe T, Kiyonari H, Ohno K, and Hagiwara M
- Journal Title
  
  Cell Reports.
  
  Volume: 23 Issue: 5 Pages: 1326-1341
- NAID
  120006463742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles - Meta-analyses of gene expression profiles2018
- Author(s)
  Hiroshi Nishiwak,i, Ito Mikako , Shuto Negishi, Sobue Sayaka, Ichihara Masatoshi, Ohno Kinji
- Journal Title
  
  Free Radic Res.
  
  Volume: - Issue: 4 Pages: 1-12
- DOI
  10.1080/10715762.2018.1439166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07094, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-26870682
[Journal Article] Promethazine hydrochloride inhibits ectopic fat cell formation in skeletal musce.2017
- Author(s)
  Kasai T, Tsuchida, K. et al.,
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 187 Issue: 12 Pages: 2627-2634
- DOI
  10.1016/j.ajpath.2017.08.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08599, KAKENHI-PROJECT-17K01485, KAKENHI-PROJECT-17K11495, KAKENHI-PROJECT-15H04840
[Journal Article] Splicing regulation and dysregulation of cholinergic genes expressed at the neuromuscular junction2017
- Author(s)
  Ohno, K. Rahman, M. A. Nazim, M. Nasrin, F. Lin, Y. Takeda, J. I. Masuda, A.
- Journal Title
  
  J Neurochem
  
  Volume: 印刷中 Issue: S2 Pages: 64-72
- DOI
  10.1111/jnc.13954
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Protein-anchoring therapy of biglycan for mdx mouse model of Duchenne muscular dystrophy2017
- Author(s)
  Ito M*, Ehara Y*, Li J, Inada K, Ohno K. *Equal contribution.
- Journal Title
  
  Hum Gene Ther
  
  Volume: - Issue: 5 Pages: 428-436
- DOI
  10.1089/hum.2015.088
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-17K07094
[Journal Article] Maternal administration of meclozine for the treatment of foramen magnum stenosis in transgenic mice with achondroplasia2017
- Author(s)
  Matsushita M, Mishima K, Esaki R, Ishiguro N, Ohno K, Kitoh H
- Journal Title
  
  J Neurosurg Pediatr
  
  Volume: 19 Issue: 1 Pages: 91-95
- DOI
  10.3171/2016.7.peds16199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10439, KAKENHI-PROJECT-16K10854, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-17H04312, KAKENHI-PROJECT-15K15548
[Journal Article] Wnt/β-catenin signaling suppresses expressions of Scx, Mkx, and Tnmd in tendon-derived cells2017
- Author(s)
  Kishimoto Yasuzumi、Ohkawara Bisei、Sakai Tadahiro、Ito Mikako、Masuda Akio、Ishiguro Naoki、Shukunami Chisa、Docheva Denitsa、Ohno Kinji
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 7 Pages: e0182051-e0182051
- DOI
  10.1371/journal.pone.0182051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15H04840
[Journal Article] An ENU-induced splice site mutation of mouse Col1a1 causing recessive osteogenesis imperfecta and revealing a novel splicing rescue.2017
- Author(s)
  Tabeta K, Du X, Arimatsu K, Yokoji M, Takahashi N, Amizuka N, Hasegawa T, Crozat K, Maekawa T, Miyauchi S, Matsuda Y, Ida T, Kaku M, Hoebe K, Ohno K, Yoshie H, Yamazaki K, Moresco EMY, Beutler B
- Journal Title
  
  Sci. Rep.
  
  Volume: 7(1) Issue: 1 Pages: 11717-11717
- DOI
  10.1038/s41598-017-10343-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15K15704, KAKENHI-PROJECT-17K19747, KAKENHI-PROJECT-15KK0337, KAKENHI-PROJECT-26293407, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16H06272, KAKENHI-PROJECT-17H06701
[Journal Article] SRSF1 suppresses selection of intron-distal 5′ splice site of DOK7 intron 4 to generate functional full-length Dok-7 protein2017
- Author(s)
  Ahsan Khalid Bin、Masuda Akio、Rahman Mohammad Alinoor、Takeda Jun-ichi、Nazim Mohammad、Ohkawara Bisei、Ito Mikako、Ohno Kinji
- Journal Title
  
  Sceintific Reports
  
  Volume: 7 Issue: 1 Pages: 10446-10446
- DOI
  10.1038/s41598-017-11036-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling2017
- Author(s)
  Miyamoto Kentaro、Ohkawara Bisei、Ito Mikako、Masuda Akio、Hirakawa Akihiro、Sakai Tadahiro、Hiraiwa Hideki、Hamada Takashi、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 9 Pages: e0184388-e0184388
- DOI
  10.1371/journal.pone.0184388
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16K15661
[Journal Article] Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders2017
- Author(s)
  Ohno Kinji、Ohkawara Bisei、Ito Mikako
- Journal Title
  
  Expert Opin Ther Targets.
  
  Volume: 21 Issue: 10 Pages: 949-958
- DOI
  10.1080/14728222.2017.1369960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15H04840
[Journal Article] Progression of Parkinson's disease is associated with gut dysbiosis: Two-year follow-up study2017
- Author(s)
  Minato Tomomi、Maeda Tetsuya、Fujisawa Yoshiro、Tsuji Hirokazu、Nomoto Koji、Ohno Kinji、Hirayama Masaaki
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 11 Pages: e0187307-e0187307
- DOI
  10.1371/journal.pone.0187307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-15K09350
[Journal Article] Six GU-rich (6GUR) FUS-binding motifs detected by normalization of CLIP-seq by Nascent-seq2017
- Author(s)
  Takeda J, Masuda A, Ohno K.
- Journal Title
  
  Gene
  
  Volume: 618 Pages: 57-64
- DOI
  10.1016/j.gene.2017.04.008
- NAID
  120006331826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms2017
- Author(s)
  Nazim M, Masuda A, Rahman MA, Nasrin F, Takeda JI, Ohe K, Ohkawara B, Ito M, Ohno K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: - Pages: 1455-1468
- DOI
  10.1093/nar/gkw823
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K10050, KAKENHI-PROJECT-15K06755
[Journal Article] R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5.2016
- Author(s)
  Nakashima H., Ohkawara B., Ishigaki S., Fukudome T., Ito K., Tsushima M., Konishi H., Okuno T., Yoshimura T., Ito M., Masuda A., Sobue G., Kiyama H., Ishiguro N., Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 22 Issue: 1 Pages: 28512-28512
- DOI
  10.1038/srep28512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-16K07055, KAKENHI-ORGANIZER-26117001
[Journal Article] Molecular hydrogen suppresses activated Wnt-catenin signaling.2016
- Author(s)
  Y. Lin, B. Ohkawara, M. Ito, N. Misawa, K. Miyamoto, Y. Takegami, A. Masuda, S. Toyokuni, K Ohno
- Journal Title
  
  Scientific Report
  
  Volume: 25 Issue: 1 Pages: 31986-31986
- DOI
  10.1038/srep31986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755
[Journal Article] Global identification of hnRNP A1 binding sites for SSO-based splicing modulation2016
- Author(s)
  Bruun GH, Doktor TK, Borch J-J, Masuda A, Krainer AR, Ohno K, Andresen BS.
- Journal Title
  
  BMC Biol
  
  Volume: 14 Issue: 1 Pages: 54-54
- DOI
  10.1186/s12915-016-0279-9
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-15K06755
[Journal Article] Is the serum creatine kinase level elevated in congenital myasthenic syndrome?2016
- Author(s)
  Ohno K.
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 87 (8) Issue: 8 Pages: 801-801
- DOI
  10.1136/jnnp-2016-313416
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04840
[Journal Article] IntSplice: Prediction of the splicing consequences of intronic single nucleotide variations in the human genome2016
- Author(s)
  Shibata A, Okuno T, Rahman MA, Azuma Y, Takeda J, Masuda A, Ohno K.
- Journal Title
  
  J Hum Genet
  
  Volume: in press
- NAID
  120005851030
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-25118508
[Journal Article] FUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysis2016
- Author(s)
  Akio Masuda. Takeda, J. I. Ohno, K.
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: in press Issue: 3 Pages: 330-340
- DOI
  10.1002/wrna.1338
- NAID
  120005893268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15H04840
[Journal Article] Tranilast stimulates endochondral ossification by upregulating SOX9 and RUNX2 promoters.2016
- Author(s)
  Hasegawa S, Kitoh H, Ohkawara B, Mishima K, Matsushita M, Masuda A, Ishiguro N, Ohno K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 470(2) Issue: 2 Pages: 356-61
- DOI
  10.1016/j.bbrc.2016.01.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-26670660, KAKENHI-PROJECT-25861306, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K15548
[Journal Article] IntSplice: Prediction of the splicing consequences of intronic single nucleotide variations in the human genome2016
- Author(s)
  Shibata A, Okuno T, Rahman MA, Azuma Y, Takeda J, Masuda A, Ohno K.
- Journal Title
  
  J Hum Genet
  
  Volume: in press
- NAID
  120005851030
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Journal Article] Mutations causing slow-channel myasthenia reveal that a valine ring in the channel pore of muscle AChR is optimized for stabilizing channel gating2016
- Author(s)
  Shen X-M*, Okuno T*, Milone M, Otsuka K, Takahashi K, Komaki H, Giles E, Ohno K, Engel AG. *Equal contribution.
- Journal Title
  
  Hum Mutat
  
  Volume: 37 Issue: 10 Pages: 1051-1059
- DOI
  10.1002/humu.23043
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Journal Article] FUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysis2016
- Author(s)
  Masuda A, Takeda J, Ohno K.
- Journal Title
  
  Wiley Interdiscip Rev RNA
  
  Volume: in press
- NAID
  120005893268
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25118508
[Journal Article] Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy2016
- Author(s)
  1.Chen G, Masuda A, Konishi H, Ohkawara B, Ito M, Kinoshita M, Kiyama H, Matsuura T, Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 25317-25317
- DOI
  10.1038/srep25317
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-26670170, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-16K07055
[Journal Article] Recent advances in congenital myasthenic syndromes2016
- Author(s)
  Ohno K, Ohkawara B, Ito M.
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 7 Issue: 3 Pages: 246-259
- DOI
  10.1111/cen3.12316
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04840
[Journal Article] Impaired Synaptic Development, Maintenance, and Neuromuscular Transmission in LRP4-Related Myasthenia.2015
- Author(s)
  Selcen D, Ohkawara B, Shen XM, McEvoy K, Ohno K, Engel AG.
- Journal Title
  
  JAMA Neurol.
  
  Volume: 72(8) Issue: 8 Pages: 889-96
- DOI
  10.1001/jamaneurol.2015.0853
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15H04840
[Journal Article] FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization.2015
- Author(s)
  Udagawa, T., Fujioka, Y., Tanaka, M., Honda, D., Yokoi, S., Riku, Y., Ibi, D., Nagai, T., Yamada, K., Watanabe, H., Katsuno, M., Inada, T., Ohno, K., Sokabe, M., Okado, H., Ishigaki S*., and Sobue, G.
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 7098-7098
- DOI
  10.1038/ncomms8098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09310, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-26116003, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-24247028, KAKENHI-PROJECT-15H06719, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-25860708, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
[Journal Article] Congenital myasthenic syndrome in Japan: ethnically unique mutations in muscle nicotinic acetylcholine receptor subunits2015
- Author(s)
  Azuma Y, Nakata T, Tanaka M, Shen XM, Ito M, Iwata S, Okuno T, Nomura Y, Ando N, Ishigaki K, Ohkawara B, Masuda A, Natsume J, Kojima S, Sokabe M, Ohno K.
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 25(1) Issue: 1 Pages: 60-69
- DOI
  10.1016/j.nmd.2014.09.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-24247028
[Journal Article] Splicing aberrations in congenital myasthenic syndromes2015
- Author(s)
  Rahman MA, Ohno K.
- Journal Title
  
  J Investig Genomics
  
  Volume: 2 Issue: 5 Pages: 38-38
- DOI
  10.15406/jig.2015.02.00038
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-15H04840
[Journal Article] SRSF1 and hnRNP H antagonistically regulate splicing of COLQ exon 16 in a congenital myasthenic syndrome.2015
- Author(s)
  Rahman MA, Azuma Y, Nasrin F, Takeda J, Nazim M, Bin Ahsan K, Akio Masuda, Engel AG, Ohno K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 13208-13208
- DOI
  10.1038/srep13208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06755, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Position-specific binding of FUS to nascent RNA regulates mRNA length.2015
- Author(s)
  Masuda A, Takeda J, Okuno T, Okamoto T, Ohkawara B, Ito M, Ishigaki S, Sobue G, Ohno K.
- Journal Title
  
  Genes Dev.
  
  Volume: 29(10) Issue: 10 Pages: 1045-57
- DOI
  10.1101/gad.255737.114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-25430049, KAKENHI-PUBLICLY-25118508, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling.2015
- Author(s)
  Otsuka K, Ito M, Ohkawara B, Masuda A, Kawakami Y, Sahashi K, Nishida H, Mabuchi N, Takano A, Engel AG, Ohno K.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 13928-13928
- DOI
  10.1038/srep13928
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Decoding abnormal splicing code in human diseases2015
- Author(s)
  Rahman MA, Nasrin F, Masuda A, Ohno K.
- Journal Title
  
  J Invest Genomics
  
  Volume: 2(1) Issue: 1 Pages: 00016-00016
- DOI
  10.15406/jig.2015.02.00016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25118508
[Journal Article] A missense mutation in domain III in HSPG2 in Schwartz-Jampel syndrome compromises secretion of perlecan into the extracellular space.2015
- Author(s)
  Iwata S, Ito M, Nakata T, Noguchi Y, Okuno T, Ohkawara B, Masuda A, Goto T, Adachi M, Osaka H, Nonaka R, Arikawa-Hirasawa E, Ohno K.
- Journal Title
  
  Neuromuscul Disord.
  
  Volume: 25(8) Issue: 8 Pages: 667-71
- DOI
  10.1016/j.nmd.2015.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K09326, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
[Journal Article] Lansoprazole upregulates polyubiquitination of TRAF6 and facilitates Runx2-mediated osteoblastogenesis2015
- Author(s)
  Kenichi Mishima, Hiroshi Kitoh, Bisei Ohkawara, Tatsuya Okuno, Mikako Ito, Akio Masuda, Naoki Ishiguro, Kinji Ohno
- Journal Title
  
  EBio Medicin
  
  Volume: 2 Issue: 12 Pages: 20462061-20462061
- DOI
  10.1016/j.ebiom.2015.11.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K15548, KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-26670660, KAKENHI-PROJECT-25861306
[Journal Article] Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains2014
- Author(s)
  4.Kobayashi M, Ohno T, Ihara K,　Murai, A., Kumazawa, M., Hoshino, H., Iwanaga, K., Iwai, H., Hamana, Y., Ito, M., Ohno, K., Horio, M..
- Journal Title
  
  Plos One
  
  Volume: 9 Issue: 5 Pages: e96271-e96271
- DOI
  10.1371/journal.pone.0096271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24370066, KAKENHI-PROJECT-24380068, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25450166
[Journal Article] HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform2014
- Author(s)
  Nasrin F, Rahman MA, Masuda A, Ohe K, Takeda J, Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 6841-6841
- DOI
  10.1038/srep06841
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PUBLICLY-25118508
[Journal Article] Collagen Q is a key player for developing rational therapy for congenital myasthenia and for dissecting the mechanisms of anti-MuSK myasthenia gravis.2014
- Author(s)
  Ohno K, Ito M, Kawakami Y, Ohtsuka K.
- Journal Title
  
  J Mol Neurosci
  
  Volume: 53(3) Issue: 3 Pages: 359-361
- DOI
  10.1007/s12031-013-0170-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-25670164
[Journal Article] Clinical and genetic analysis of the first known Asian family with myotonic dystrophy type 22014
- Author(s)
  Nakayama T, Nakamura H, Oya Y, Kimura T, Imahuku I, Ohno K, Nishino I, Abe K, Matsuura T.
- Journal Title
  
  J Hum Genet
  
  Volume: 59 Issue: 3 Pages: 129-133
- DOI
  10.1038/jhg.2013.133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-26670170
[Journal Article] LDB3 splicing abnormalities are specific to skeletal muscles of patients with myotonic dystrophy type 1 and alter its PKC binding affinity2014
- Author(s)
  Yamashita Y, Matsuura T, Kurosaki T, Amakusa Y, Kinoshita M, Ibi T, Sahashi K, Ohno K.
- Journal Title
  
  Neurobiol Disord
  
  Volume: 69 Pages: 200-205
- DOI
  10.1016/j.nbd.2014.05.026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-26670170, KAKENHI-PROJECT-24390083
[Journal Article] LRP4 third β-propeller domain mutations cause novel congenital myasthenia by compromising agrin-mediated MuSK signaling in a position-specific manner2014
- Author(s)
  Ohkawara B, Cabrera-Serrano M, Nakata T, Milone M, Asai N, Ito K, Ito M, Masuda A, Ito Y, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet.
  
  Volume: Apr 1;23(7) Issue: 7 Pages: 1856-68
- DOI
  10.1093/hmg/ddt578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23710253, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164, KAKENHI-PROJECT-15H04840
[Journal Article] A Kir3.4 mutation causes Andersen–Tawil syndrome by an inhibitory effect on Kir2.1.2014
- Author(s)
  Kokunai Y, Nakata T, Furuta M, Sakata S, Kimura H, Aiba T, Yoshinaga M, Osaki Y, Nakamori M, Itoh H, Sato T, Kubota T, Kadota K, Shindo K, Mochizuki H, Shimizu W, Horie M, Okamura Y, Ohno K, Takahashi MP
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 12 Pages: 1058-64
- DOI
  10.1212/wnl.0000000000000239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591245, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24591086, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-25460406, KAKENHI-PROJECT-25860163, KAKENHI-PROJECT-25713034
[Journal Article] Clinically applicable antianginal agents suppress osteoblastic transformation of myogenic cells and heterotopic ossifications in mice2013
- Author(s)
  Yamamoto R, Matsushita M, Kitoh H, Masuda A, Ito M, Katagiri T, Kawai T, Ishiguro N, Ohno K
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 31 Pages: 26-33
- DOI
  10.1007/s00774-012-0380-2
- NAID
  10031168834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-24592278
[Journal Article] HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA.2013
- Author(s)
  Rahman, M. A., Masuda, A., Ohe, K., Ito, M. , Hutchinson, D. O., Mayeda, A., Engel, A. G. and Ohno, K.
- Journal Title
  
  Sci. Rep.
  
  Volume: 3 Issue: 1 Pages: 2931-2931
- DOI
  10.1038/srep02931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24591920, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164
[Journal Article] Clinically applicable antianginal agents suppress osteoblastic transformation of myogenic cells and heterotopic ossifications in mice.2013
- Author(s)
  Yamamoto R, Matsushita M, Kitoh H, Masuda A, Ito M, Katagiri T, Kawai T, Ishiguro N, Ohno K.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 31 Pages: 26-33
- NAID
  10031168834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.2013
- Author(s)
  Matsushita, M., Kitoh, H., Ohkawara, B., Mishima, K., Kaneko, H., Ito, M., Masuda, A., Ishiguro, N. and Ohno, K.
- Journal Title
  
  PLOS ONE
  
  Volume: 8(12) Issue: 12 Pages: 81569-81569
- DOI
  10.1371/journal.pone.0081569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-23710253, KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-24592259, KAKENHI-PROJECT-24659671, KAKENHI-PROJECT-25430049
[Journal Article] Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells.2013
- Author(s)
  Iio A, Ito M, Itoh T, Terazawa R, Fujita Y, Nozawa Y, Ohsawa I, Ohno K, Ito M.
- Journal Title
  
  Med Gas Res
  
  Volume: 3 Pages: 6-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Mutations in the C-Terminal Domain of ColQ in Endplate Acetylcholinesterase Deficiency Compromise ColQ-MuSK Interaction.2013
- Author(s)
  Nakata T, Ito M, Azuma Y, Otsuka K, Noguchi Y, Komaki H, Okumura A, Shiraishi K, Masuda A, Natsume J, Kojima S, Ohno K.
- Journal Title
  
  Human Mutation
  
  Volume: in press Issue: 7 Pages: 997-1004
- DOI
  10.1002/humu.22325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25670164
[Journal Article] hDbr1 is a nucleocytoplasmic shuttling protein with a protein phosphatase-like motif essential for debranching activity2013
- Author(s)
  Kataoka, N. Hagiwara, M. and Ohno, M
- Journal Title
  
  Sci. Rep
  
  Volume: 3-1090 Issue: 1 Pages: 1090-1090
- DOI
  10.1038/srep01090
- NAID
  120005241441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20112007, KAKENHI-PROJECT-22603002, KAKENHI-ORGANIZER-20112001, KAKENHI-PUBLICLY-23112706, KAKENHI-PROJECT-21249013
[Journal Article] Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Krejci E, Engel AG
- Journal Title
  
  Chem Biol Interact
  
  Volume: 203(1) Issue: 1 Pages: 335-340
- DOI
  10.1016/j.cbi.2012.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670164
[Journal Article] Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells2013
- Author(s)
  Iio A, Ito M, Itoh T, Terazawa R, Fujita Y, Nozawa Y, Ohsawa I, Ohno K, Ito M
- Journal Title
  
  Med Gas Res
  
  Volume: 3 Issue: 1 Pages: 6-6
- DOI
  10.1186/2045-9912-3-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500882, KAKENHI-PROJECT-25430049
[Journal Article] Gfpt1-myasthenia: Clinical, structural, and electrophysiologic heterogeneity2013
- Author(s)
  Selcen D, Shen XM, Milone M, Brengman J, Ohno K, Deymeer F, Finkel R, Rowin J, Engel AG.
- Journal Title
  
  Neurology
  
  Volume: 81 Issue: 4 Pages: 378-378
- DOI
  10.1212/wnl.0b013e31829c5e9c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-25670164
[Journal Article] Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial.2013
- Author(s)
  Kitoh H, Achiwa M, Kaneko H, Mishima K, Matsushita M, Kadono I, Horowitz JD, Sallustio BC, Ohno K, Ishiguro N.
- Journal Title
  
  Orphanet J Rare Dis.
  
  Volume: 8 Issue: 1 Pages: 163-163
- DOI
  10.1186/1750-1172-8-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249076, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-24592259, KAKENHI-PROJECT-24659671
[Journal Article] Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes.2013
- Author(s)
  Tanisawa K., Mikami E., Fuku N., Honda Y., Honda S., Ohsawa I., Ito M., Endo S., Ihara K., Ohno K., Kishimoto Y., Ishigami A., Maruyama N., Sawabe M., Iseki H., Okazaki Y., Hasegawa-Ishii S., Takei S., Shimada A., Hosokawa M., Mori M., Higuchi K., Takeda T., Higuchi M., Tanaka M.
- Journal Title
  
  BMC Genomics.
  
  Volume: 14(1): Issue: 1 Pages: 248-248
- DOI
  10.1186/1471-2164-14-248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J40278, KAKENHI-PROJECT-21570243, KAKENHI-PROJECT-22240072, KAKENHI-PROJECT-23617041, KAKENHI-PROJECT-24370066, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500487, KAKENHI-PROJECT-24500882, KAKENHI-PROJECT-24650331, KAKENHI-PROJECT-25242062, KAKENHI-PROJECT-25560382, KAKENHI-PROJECT-25670164
[Journal Article] S100A10 is required for the organization of actin stress fibers and promotion of cell spreading.2013
- Author(s)
  Shurovi Sayeed
- Journal Title
  
  Molecular and cellular biochemistry
  
  Volume: 374 Issue: 1-2 Pages: 105-11
- DOI
  10.1007/s11010-012-1509-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570182, KAKENHI-PROJECT-22590268, KAKENHI-PROJECT-24390221
[Journal Article] Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson's disease in rats.2012
- Author(s)
  Ito M, Hirayama M, Yamai K, Goto S, Ito M, Ichihara M, Ohno K.
- Journal Title
  
  Med Gas Res
  
  Volume: 2 Pages: 15-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson's disease in rats2012
- Author(s)
  Ito M, Hirayama M, Yamai K, Goto S, Ito M, Ichihara M, Ohno K
- Journal Title
  
  Med Gas Res
  
  Volume: 2 Issue: 1 Pages: 15-15
- DOI
  10.1186/2045-9912-2-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24590768
[Journal Article] Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.2012
- Author(s)
  Ohno K, Ito M, Ichihara M, Ito M.
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2012 Pages: 353152-353152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Four parameters increase the sensitivity and specificity of the exon array analysis and disclose twenty-five novel aberrantly spliced exons in myotonic dystrophy.2012
- Author(s)
  Yamashita Y, Matsuura T, Shinmi J, Amakusa Y, Masuda A, Ito M, Kinoshita M, Furuya H, Abe K, Ibi T, Sahashi K, Ohno K.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 57 Issue: 6 Pages: 368-374
- DOI
  10.1038/jhg.2012.37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659455, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390083, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469
[Journal Article] CUGBP1 and MBNL1 preferentially bind to 3’ UTRs and facilitate mRNA decay2012
- Author(s)
  Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito M, Andresen BS, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 2 Issue: 1 Pages: 209-209
- DOI
  10.1038/srep00209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-24390221
[Journal Article] Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases2012
- Author(s)
  Ohno K, Ito M, Ichihara M, Ito M
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2012 Pages: 353152-353152
- DOI
  10.1155/2012/353152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-24590768
[Journal Article] A novel mutation in SCN4A causes severe myotonia and school-age-onset paralytic episodes2012
- Author(s)
  Yoshinaga Y. Sakoda S-I, Good JM, Takahashi MP, Kubota T, Arikawa-Hirasawa E, Nakata T, Ohno K, Kitamura T, Kobayashi K, Ohtsuka Y
- Journal Title
  
  J Neurol Sci
  
  Volume: 315(1-2) Issue: 1-2 Pages: 15-9
- DOI
  10.1016/j.jns.2011.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591245, KAKENHI-PROJECT-24390221
[Journal Article] Muscle-Specific Splicing Factors ASD-2 and SUP-12 Cooperatively Switch Alternative Pre-mRNA Processing Patterns of the ADF/Cofilin Gene in Caenorhabditis elegans2012
- Author(s)
  Ohno G, Ono K, Togo M, Watanabe Y, Ono S, Hagiwara M, Kuroyanagi H
- Journal Title
  
  PLoS Genetics
  
  Volume: 8 Issue: 10 Pages: e1002991-e1002991
- DOI
  10.1371/journal.pgen.1002991
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20112004, KAKENHI-PROJECT-21249013, KAKENHI-PROJECT-22500288, KAKENHI-PROJECT-24657116, KAKENHI-ORGANIZER-20112001
[Journal Article] A novel mutation in SCN4A causes severe myotonia and school-age-onset paralytic episodes2012
- Author(s)
  Yoshinaga H, Sakoda S, Good JM, Takahashi MP, Kubota T, Arikawa-Hirasawa E, Nakata T, OhnoK, Kitamura T, Kobayashi K, Ohtsuka Y
- Journal Title
  
  J Neurol Sci
  
  Volume: 315 Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] CUGBP1 and MBNL1 preferentially bind to 3' UTRs and facilitate mRNA decay2012
- Author(s)
  Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito M, Andresen BS, Ohno K
- Journal Title
  
  Scientific Reports
  
  Volume: 2 Pages: 209-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Muscle - specific splicing factors ASD - 2 and SUP - 12 cooperatively switch alternative pre - mRNA processing patterns of the ADF/cofilin gene in C. elegans .2012
- Author(s)
  Ohno G , Ono K , Togo M , Watanabe Y , Ono S ,Hagiwara M , Kuroyanagi H
- Journal Title
  
  PLoS Genet
  
  Volume: 8(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Protein-anchoring strategy for delivering acetylcholinesterase to the neuromuscular junction2012
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Journal Title
  
  Mol Ther
  
  Volume: (印刷中) Issue: 7 Pages: 1384-1392
- DOI
  10.1038/mt.2012.34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266, KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-22390284, KAKENHI-PROJECT-23700422, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469
[Journal Article] The unstable CCTG repeat responsible for myotonic dystrophy type 2 originates from an AluSx element insertion into an early primate genome2012
- Author(s)
  Kurosaki, T., Ueda, S., Ishida, T., Abe, K., Ohno, K. and Matsuura, T
- Journal Title
  
  PLos One
  
  Volume: 7 Issue: 6 Pages: e38379-e38379
- DOI
  10.1371/journal.pone.0038379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23657170, KAKENHI-PROJECT-24390083, KAKENHI-PROJECT-24390221
[Journal Article] Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions.2012
- Author(s)
  Ishigaki S, Masuda A, Fujioka Y, Iguchi Y, Katsuno M, Shibata A, Urano F, Sobue G, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 2 Issue: 1 Pages: 529-529
- DOI
  10.1038/srep00529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659452, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659429, KAKENHI-PLANNED-22110005
[Journal Article] Myotonic dystrophy type 2 (DM2) is rare in the Japanese population2012
- Author(s)
  Matsuura T, Minami N, Arahata H, Ohno K, Abe K, Hayashi YK, Nishino I
- Journal Title
  
  J Hum Genet
  
  Volume: (印刷中) Issue: 3 Pages: 219-220
- DOI
  10.1038/jhg.2011.152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266, KAKENHI-PROJECT-23659455, KAKENHI-PROJECT-24390083, KAKENHI-PROJECT-24390221
[Journal Article] Molecular hydrogen inhibits lipopolysaccharide/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages2011
- Author(s)
  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 411 Issue: 1 Pages: 143-149
- DOI
  10.1016/j.bbrc.2011.06.116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266, KAKENHI-PROJECT-22300244
[Journal Article] Urinary 8-hydroxydeoxyguanosine correlate with hallucinations rather than motor symptoms in Parkinson's disease2011
- Author(s)
  Hirayama M, Nakamura T, Watanabe H, Uchida K, Hama T, Hara T, Niimi Y, Ito M, Ohno K, Sobue G
- Journal Title
  
  Parkinsonism Relat Disord
  
  Volume: 17 Pages: 46-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies2011
- Author(s)
  Ito M, Ibi T, Sahashi K, Ichihara M, Ito M, Ohno K
- Journal Title
  
  Med Gas Res
  
  Volume: 1 Issue: 1 Pages: 24-24
- DOI
  10.1186/2045-9912-1-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.2011
- Author(s)
  Ito M, Ibi T, Sahashi K, Ichihara M, Ito M, Ohno K.
- Journal Title
  
  Med Gas Res
  
  Volume: 1 Pages: 24-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Anti-MuSK autoantibodies block binding of collagen Q to MuSK2011
- Author(s)
  Kawakami Y, Ito M, Hirayama M, Sahashi K, Ohkawara B, Masuda A, Nishida H, Mabuchi N, Engel A G, Ohno K
- Journal Title
  
  Neurology
  
  Volume: 77 Pages: 1819-1826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] The 2011 Medical Molecular Hydrogen Symposium : An inaugural symposium of the journal Medical Gas Research2011
- Author(s)
  Ohta S, Nakao A, Ohno K
- Journal Title
  
  Med Gas Res
  
  Volume: 1 Issue: 1 Pages: 10-10
- DOI
  10.1186/2045-9912-1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244, KAKENHI-PROJECT-23300257, KAKENHI-PROJECT-24651055
[Journal Article] Molecular hydrogen inhibits lip polysaccharide/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages2011
- Author(s)
  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 411 Pages: 143-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Myasthenic syndrome caused by plectinopathy2011
- Author(s)
  Selcen D, Juel VC, Hobson-Webb LD, Smith EC, Stickler DE, Bite AV, Ohno K, Engel AG
- Journal Title
  
  Neurology
  
  Volume: 76 Pages: 327-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA2011
- Author(s)
  Kataoka N, Diem MD, Yoshida M, Hatai C, Dobashi I, Dreyfuss G, Hagiwara M, Ohno M
- Journal Title
  
  Sci Rep
  
  Volume: 1:92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.2011
- Author(s)
  Itoh T, Hamada N, Terazawa R, Ito M, Ohno K, Ichihara M, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 411 Pages: 143-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] AG-dependent 3'-splice sites are predisposed to aberrant splicing due to amutation at the first nucleotide of an exon2011
- Author(s)
  Fu Y, Masuda A, Ito M, Shinmi J, Ohno K
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 39 Pages: 4396-4404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Urinary 8-hydroxydeoxyguanosine correlate with hallucinations rather than motor symptoms in Parkinson's disease2011
- Author(s)
  Hirayama M, Nakamura T, Watanabe H, Uchida K, Hama T, Hara T, Niimi Y, Ito M, Ohno K, Sobue G
- Journal Title
  
  Parkinsonism and Related Disorders
  
  Volume: 17 Issue: 1 Pages: 46-49
- DOI
  10.1016/j.parkreldis.2010.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300244
[Journal Article] Hyperuricemia cosegregating with osteogenesis imperfecta is associated with amutation in2011
- Author(s)
  Kaneko H, Kitoh H, Matsuura T, Masuda A, Ito M, Mottes M, Rauch F, Ishiguro N, Ohno K
- Journal Title
  
  GPATCH8
  
  Volume: 130 Pages: 671-683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] AG-dependent 3'-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon.2011
- Author(s)
  Fu Y, Masuda A, Ito M, Shinmi J, Ohno K.
- Journal Title
  
  Nucleic Acids Res. 39(10)
  
  Pages: 4396-4404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Hyperuricemia cosegregating with osteogenesis imperfecta is associated with a mutation in GPATCH82011
- Author(s)
  Kaneko H, Kitoh H, Matsuura T, Masuda A, Ito M, Mottes M, Rauch F, Ishiguro N, Ohno K
- Journal Title
  
  Hum Genet
  
  Volume: 130 Issue: 5 Pages: 671-683
- DOI
  10.1007/s00439-011-1006-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266, KAKENHI-PROJECT-21390419, KAKENHI-PROJECT-21591915, KAKENHI-PROJECT-22659269, KAKENHI-PROJECT-22659270
[Journal Article] RNA pathologies in neurological disorders. Neurochemical Mechanisms in Disease, Advances in Neurobiology2011
- Author(s)
  Ohno K, Masuda A
- Journal Title
  
  (Ed by Abel Lajtha)(Springer, New York)
  
  Pages: 399-415
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Myasthenic syndrome caused by plectinopathy2011
- Author(s)
  Selcen D, Juel VC, Hobson-Webb LD, Smith EC, Stickler DE, Bite AV, Ohno K, Engel AG
- Journal Title
  
  Neurology
  
  Volume: 76 Pages: 327-336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] AG-dependent 3'-splice sites are predisposed to aberrant splicing due to a mutation at the first nucleotide of an exon2011
- Author(s)
  Fu Y, Masuda A, Ito M, Shinmi J, Ohno K
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 39 Issue: 10 Pages: 4396-4404
- DOI
  10.1093/nar/gkr026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Visualization and genetic analysis ofalternative splicing regulation in vivo using fluorescence reporters in transgenic Caenorhabditis elegans.2010
- Author(s)
  Kuroyanagi H, Ohno G, Sakane, H, Maruoka, H, and Hagiwara M
- Journal Title
  
  Nature Protoc.
  
  Volume: 5 Pages: 1495-1517
- Data Source
  KAKENHI-PROJECT-21249013
[Journal Article] Myasthenic syndrome due to defects in rapsyn : Clinical and molecular findings in 39 patients2009
- Author(s)
  Milone M, Shen XM, Selcen D, Ohno K, Brengman J, Iannaccone ST, Harper CM, Engel AG
- Journal Title
  
  Neurology
  
  Volume: 73 Pages: 228-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Alu-mediated acquisition of unstable ATTCT pentanucleotide repeats in the human ATXN10 gene.2009
- Author(s)
  Kurosaki T, Matsuura T, Ohno K, Ueda S
- Journal Title
  
  Mol Biol Evol 26
  
  Pages: 2573-2579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Ancestral origin of the ATTCT repeat expansion in spinocerebellar ataxia type 10 (SCA10)2009
- Author(s)
  Almeida T, Alonso I, Martins S, Ramos EM, Azevedo L, Ohno K, Amorim A, Saraiva-Pereira ML, Jardim LB, Matsuura T, Sequeiros J, Silveira I.
- Journal Title
  
  PLoS ONE Vol. 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Myasthenic syndrome due to defects in rapsyn : Clinical and molecular findings in 39 patients.2009
- Author(s)
  Milone M, Shen XM, Selcen D, Ohno K, Brengman J, Iannaccone ST, Harper CM, Engel AG.
- Journal Title
  
  Neurology Vol.73
  
  Pages: 228-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun Vol. 389
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Ancestral Origin of the ATTCT Repeat Expansion in Spinocerebellar Ataxia Type 10 (SCA10).2009
- Author(s)
  Almeida T, Alonso I, Martins S, Ramos EM, Azevedo L, Ohno K, Amorim A, Saraiva-Pereira ML, Jardim LB, Matsuura T, et. al.
- Journal Title
  
  PLoS One 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun. 389(4)
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3Adue to an hnRNP H-disrupting mutation in congenital myasthenic syndrome2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet
  
  Volume: 18 Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Comm un Vol.389
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Alu-mediated acquisition of unstable ATTCT pentanucleotide repeats in the human ATXN10 gene.2009
- Author(s)
  Kurosaki T, Matsuura T, Ohno K, Ueda S.
- Journal Title
  
  Mol Bibl Evol Vol.26
  
  Pages: 2573-2579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Ancestral origin of the ATTCT repeat expansion in spinocerebellar ataxia type 10 (SCA10).2009
- Author(s)
  Almeida T, Alonso I, Martins S, Ramos EM, Azevedo L, Ohno K, Amorim A, Saraiva-Pereira ML, Jardim LB, Matsuura T, Sequeiros J, Silveira I.
- Journal Title
  
  PLoS ONE Vol.4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRN A1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet Vol. 18
  
  Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neurosci Lett Vol.453
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome.2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet 18
  
  Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tractbinding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome.2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet Vol.18
  
  Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Myasthenic syndrome due to defects in rapsyn : Clinical and molecular findings in 39 patients2009
- Author(s)
  Milone M, Shen XM, Selcen D, Ohno K, Brengman J, Iannaccone ST, Harper CM, Engel AG.
- Journal Title
  
  Neurology Vol. 73
  
  Pages: 228-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] SCA10. Clinical Neuroscience月刊2009
- Author(s)
  松浦徹, 大野欽司
- Journal Title
  
  臨床神経科学 27
  
  Pages: 66-68
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome2009
- Author(s)
  Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K.
- Journal Title
  
  Human Molecular Genetics 18
  
  Pages: 1229-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neurosci Lett Vol. 453
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Alu-mediated acquisition of unstable ATTCT pentanucleotide repeats in the human ATXN10 gene2009
- Author(s)
  Kurosaki T, Matsuura T, Ohno K, Ueda S.
- Journal Title
  
  Mol Biol Evol Vol. 26
  
  Pages: 2573-2579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neurosci Lett. 453(2)
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Human branch point consensus sequence is yUnAy.2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Res. 36(7)
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Human branch point consensus sequence is yunay2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K
- Journal Title
  
  Nucleic Acids Res 36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Human branch point consensus sequence is yUnAy2008
- Author(s)
  Gao R, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Research 36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome.2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet. 17(24)
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes conge nital myasthenic syndrome.2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K.
- Journal Title
  
  Hum Mol Genet Vol.17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Myotonic dystrophy type 2 in Japan: ancestral origin distinct from Caucasian families2008
- Author(s)
  Saito T, Amakusa Y, Kimura T, Yahara O, Aizawa H, Ikeda Y, Day JW, Ranum LPW, Ohno K, Matsuura T
- Journal Title
  
  Neurogenetics 9
  
  Pages: 61-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Human branch point consensus sequence is yUnAy2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Res Vol.36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Myotonic dystrophy type 2 in Japan: ancestral origin distinct from Caucasian families2008
- Author(s)
  Saito T, Amakusa, Y, Kimura T, Yahara O, Aizawa H, Ikeda Y, Day JW, Ranum LPW, Ohno K, Matsuura T
- Journal Title
  
  Neurogenetics 9
  
  Pages: 61-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Long-range PCR for the diagnosis of spinocerebellar ataxia type 10.2008
- Author(s)
  Kurosaki T, *Matsuura T, Ohno K, Ueda S
- Journal Title
  
  Neurogenetics 9
  
  Pages: 151-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet Vol.17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Myotonic dystrophy type 2 in Japan : ancestral origin distinct from Caucasian families.2008
- Author(s)
  Saito T, Amakusa Y, Kimura T, Yahara O, Aizawa H, Ikeda Y, Day JW, Ranum LPW, Ohno K, Matsuura T.
- Journal Title
  
  Neurogenetics Vol.9
  
  Pages: 61-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] HnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndromes2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K.
- Journal Title
  
  Human Molecular Genetics 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] HnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupmyasthenic syndrome.2008
- Author(s)
  Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 4022-4035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating2008
- Author(s)
  Shen X-M, Fukuda T, Ohno K, Sine SM, Engel AG
- Journal Title
  
  J Clin Invest 118
  
  Pages: 1867-1876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Long-range PCR for the diagnosis of spinocerebellar ataxia type 102008
- Author(s)
  Kurosaki T, Matsuura T, Ohno K, Ueda S
- Journal Title
  
  Neurogenetics 9
  
  Pages: 151-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Myotonic dystrophy type 2 in Japan : ancestral origin distinct from Caucasian families2008
- Author(s)
  Saito T, Amakusa Y, Kimura T, Yahara O, Aizawa H, Ikeda Y, Day JW, Ranum LPW, Ohno K, Matsuura T.
- Journal Title
  
  Neurogenetics Vol.9
  
  Pages: 61-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating2008
- Author(s)
  Shen X-M, Fukuda T, Ohno K, Sine SM, Engel AG.
- Journal Title
  
  J Clin Invest Vol.118
  
  Pages: 1867-1876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating.2008
- Author(s)
  Shen X-M, Fukuda T, Ohno K, Sine SM, Engel AG.
- Journal Title
  
  J Clin Invest Vol.118
  
  Pages: 1867-1876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Long-range PCR for the diagnosis of spinocerebellar ataxia type 10.2008
- Author(s)
  Kurosaki T, Matsuura T, Ohno K, Ueda S.
- Journal Title
  
  Neurogenetics Vol.9
  
  Pages: 151-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Human branch point consensus sequence is yUnAy.2008
- Author(s)
  Gao K, Masuda A, Matsuura T, Ohno K.
- Journal Title
  
  Nucleic Acids Res Vol.36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20016011
[Journal Article] Long-range PCR for the diagnosis of spinocerebellar ataxia type 102008
- Author(s)
  Kurosaki T, Matsuura T, Ohno K, Ueda S.
- Journal Title
  
  Neurogenetics Vol.9
  
  Pages: 151-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Viral vector-mediated expression of human collagen Q in cultured cells.2008
- Author(s)
  Ito M, Masuda A, Jinno S, Katagiri T, Krejci E, Ohno K.
- Journal Title
  
  Chem Biol Interact. 175(1-3)
  
  Pages: 346-348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities2007
- Author(s)
  Ichihara M, Murakumo Y, Masuda A, Matsuura T, Asai N, Jijiwa M, Ishida M, Shinmi J, Yatsuya H, Qiao S, Takahashi M, Ohno K
- Journal Title
  
  Nucleic Acids Res 35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities.2007
- Author(s)
  Ichihara M, Murakumo Y, Masuda A, Matsuura T, Asai N, Jijiwa M, Ishida M, Shinmi J, Yatsuya H, Qiao S, Takahashi M, Ohno K
- Journal Title
  
  Nucleic Acids Res 35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5' splice sites2007
- Author(s)
  Sahashi K, Masuda A, Matsuura T, Shinmi J, Zhang Z, Takeshima Y, Matsuo M, Sobue G, Ohno K
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 5995-6003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] Essential role of GATA transcriptional factors in the activation of mast cells2007
- Author(s)
  Masuda A, Hashimoto K, Yokoi T, Doi, T, Kodama, T, Kume, H, Ohno, K, Matsuguchi, T
- Journal Title
  
  J Immunol 178
  
  Pages: 360-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390237
[Journal Article] In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5' splice sites.2007
- Author(s)
  Sahashi K, Masuda A, Matsuura T, Shinmi J, Zhang Z, Takeshima Y, Matsuo M, Sobue G, Ohno K
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 5995-6003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Journal Article] Protein-anchoring strategy for delivering acetyl cholinesterase to the neuromuscular junction
- Author(s)
  Ito M, Suzuki Y, Okada T, FukudomeT, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Journal Title
  
  Mol Ther
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Myotonic dystrophy type 2(DM2) is rare in the Japanese populatio
- Author(s)
  Matsuura T, Minami N, Arahata H, Ohno K, Abe K, Hayashi YK, Nishino I
- Journal Title
  
  J Hum Genet in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390266
[Journal Article] Human branch point consensus sequeis yUnAy.
- Author(s)
  Gao R, Masuda A, Matsuura T, Ohno K
- Journal Title
  
  Nucleic Acids 36
  
  Pages: 2257-2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590988
[Patent] 腸内細菌叢に占めるコリンセラ属の情報を提供する方法、当該情報を用いたＣＯＶＩＤ－１９重症化予測方法およびサイトカインストーム重症化予測方法2021
- Inventor(s)
  大野欽司, 平山正昭, 西脇寛, 仲木竜, 内海貴夫
- Industrial Property Rights Holder
  東海国立大学機構
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21H04815
[Patent] 磁場発生装置および磁場照射方法2021
- Inventor(s)
  大野欽司, 伊藤美佳子, 戸田拓郎
- Industrial Property Rights Holder
  東海国立大学機構
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21H04815
[Patent] パーキンソン病の判定マーカーおよび判定方法2021
- Inventor(s)
  辻浩和,朝原崇,野本康二,平山正昭,大野欽司
- Industrial Property Rights Holder
  東海国立大学機構
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-21H04815
[Patent] Ｒ-スポンジン２によるＷｎｔ／β-カテニンシグナル活性化の制御を介した治療薬2018
- Inventor(s)
  大野欽司、石黒直樹、大河原美静、大倉俊昭
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-050199
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15H04840
[Patent] タンパク質-ＲＮＡ相互作用の検出2017
- Inventor(s)
  増田章男、大野欽司
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-137406
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04840
[Patent] パーキンソン病の判定マーカーおよび判定方法2017
- Inventor(s)
  平山正昭、大野欽司、辻浩和、朝原崇、野本康二
- Industrial Property Rights Holder
  国立大学法人名古屋大学、ヤクルト本社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-098973
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04840
[Patent] 骨格筋増量剤及びその用途2014
- Inventor(s)
  大野欽司、石黒直樹、飛田哲朗、松下雅樹
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-176248
- Filing Date
  2014-08-29
- Data Source
  KAKENHI-PROJECT-24390221
[Patent] 「骨系統疾患治療薬及びその用途」2013
- Inventor(s)
  大野欽司、石黒直樹、鬼頭浩史、松下雅樹
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-047426
- Filing Date
  2013-03-10
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Impaired gating of γ- and ε-AChR respectively causes incomplete form of Escobar syndrome without pterygium and fast-channel congenital myasthenic syndrome2023
- Author(s)
  Nakata T, Shen X-M, Mizuno S, Imoto I, Selcen D, Engel AG, Ohno K.
- Organizer
  68th Annual Meeting of the Japan Society of Human Genetics, Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27485
[Presentation] Pulsed faint electromagnetic field enhances mitochondrial electron transport chain and ameliorates depressive-like symptoms in mice with social defeat stress2023
- Author(s)
  Teranishi M, Ito M, Ohno K
- Organizer
  14th World Congress on Targeting Mitochondria (Poster), Berlin, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18273
[Presentation] Meclozine ameliorates Fgf2-induced craniofacial bone hyperossification of larval zebrafish by attenuating MAPK pathway2023
- Author(s)
  Takemoto G, Matsushita M, Ohno K, Imagama S.
- Organizer
  Orthopaedic Research Society 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Gut microbiota in dementia with Lewy bodies2023
- Author(s)
  Ohno K.
- Organizer
  2nd MCI Symposium, Kyoto, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23K27485
[Presentation] Cross-modal plasticity after early visual deprivation depends on microglial elimination of inhibitory synapses2023
- Author(s)
  Akari HASHIMOTO, Nanami KAWAMURA, Etsuko TARUSAWA, Ikuko TAKEDA, Yuki AOYAMA, Nobuhiko OHNO, Mio INOUE, Mai KAGAMIUCHI, Daisuke KATO, Mami MATSUMOTO, Yoshihiro HASEGAWA, Anne SCHAEFER, Junichi NABEKURA, Takeshi YAGI, Hiroaki WAKE
- Organizer
  Neuroscience2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Meclozine ameliorates Fgf2-induced craniofacial bone hyperossification of larval zebrafish by attenuating MAPK pathway2023
- Author(s)
  Takemoto G, Matsushita M, Ohno K, Imagama S.
- Organizer
  Orthopaedic Research Society 2023 Annual Meeting (Poster), Dallas, Texas, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Curiosity-Driven Biomedical Sciences ─水素と磁場とミトコンドリア─2023
- Author(s)
  大野欽司
- Organizer
  第１回異分野融合学芸シンポジウム、名古屋(名古屋マリオットホテル)、2023年7月22日
- Invited
- Data Source
  KAKENHI-PROJECT-23K18273
[Presentation] Gut microbiota in dementia with Lewy bodies2023
- Author(s)
  Ohno K
- Organizer
  2nd MCI Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Updates on congenital myasthenic syndromes2022
- Author(s)
  Ohno K
- Organizer
  20th Asian Oceanian Myology Center Meeting, Jakarta, Indonesia (online)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] サルブタモールが有効だったDOK-7変異による先天性筋無力症候群の姉弟例2022
- Author(s)
  小林道雄, 澤石由記夫, 大野欽司, 豊島至
- Organizer
  第40回日本神経治療学会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] 先天性筋無力症候群アップデートと神経筋接合部の構築を誘導する新規分泌因子2022
- Author(s)
  大野欽司
- Organizer
  第63回日本神経学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Painful muscle spasm with marked hyper-creatine kinase (CK) level after more than twenty weeks of four pregnant women with myotonic dystrophy type 1 (DM1) and a pregnant woman with paramyotonia congenita (PMC).2022
- Author(s)
  Kinoshita M, Hara W, Yoshida N, Miyauchi A, Yamamoto M, Oji S, Fukaura H, Kaida K, Ohno K.
- Organizer
  13th International Myotonic Dystrophy Consortium Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Three newly identified molecules that facilitate the formation of neuromuscular junction2022
- Author(s)
  大野欽司
- Organizer
  XIIth International Symposium on Cholinergic Mechanisms
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Interactions between muscle glucose homeostasis and neuromuscular signal transduction Lessons learned from lack of a muscle-specific long isoform of GFPT12022
- Author(s)
  Farshadyeganeh P, Nazim M, Ohkawara B, Masuda A, Ito M, Takeda J, Ohe K, Ohno K.
- Organizer
  European Human Genetics Conference 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Novel mutations at equivalent position in E-loops of AChR and subunits result in Escobar and congenital myasthenic syndrome respectively.2022
- Author(s)
  Shen XM, Nakata T, Mizuno S, Imoto I, Spilsbury PR, Swoboda KJ, Al-Mateen M, Selcen D, Ohno K, Engel AG.
- Organizer
  147th American Neurology Association Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Updates on congenital myasthenic syndromes2022
- Author(s)
  大野欽司
- Organizer
  20th Asian Oceanian Myology Center Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] RNPS1 in PSAP Complex Controls Precise Pre-mRNA Splicing with Periodicity during Cell Cycle2022
- Author(s)
  Fukumura K, Takeda J, Masuda A, Ohno K, Mayeda A.
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Microglial removal of inhibitory synapses unleash the multi-sensory potential in the association cortex2022
- Author(s)
  Wake H, Hashimoto A, Kawamura N, Tarusawa E, Takeda I, Ohno N, Inoue M, Kato D, Aoyama Y, Matsumoto M, Hasegawa Y.
- Organizer
  The Australian Physiological Society annual meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] 腸内細菌の変化はパーキンソン病の病態進行を予測できる2022
- Author(s)
  小関華凜, 鈴木花歩, 関口恭平, 大塚圭吾, 大野欽司, 西脇寛, 前田哲也, 坪井義夫, 柏原健一, 平山正昭
- Organizer
  第63回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] パーキンソン病患者の腸内細菌による分子状水素産生の低下2022
- Author(s)
  西脇寛, 伊藤美佳子, 大野欽司
- Organizer
  第11回日本分子状水素医学生物学会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] パーキンソン病患者腸内細菌叢の中核を担うとされるChristensenellaceae R-7の単離2022
- Author(s)
  関口恭平, 大塚圭吾, 浜口知成, 大野欽司, 小林未育, 平山正昭
- Organizer
  第63回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Three newly identified molecules that facilitate the formation of neuromuscular junction2022
- Author(s)
  Ohno K
- Organizer
  XIIth International Symposium on Cholinergic Mechanisms, Dubrovnik, Croatia (hybrid)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Novel mutations at equivalent position in E-loops of AChR γ-and ε-subunits result in Escobar and congenital myasthenic syndrome respectively2022
- Author(s)
  Shen XM, Nakata T, Mizuno S, Imoto I, Spilsbury PR, Swoboda KJ, Al-Mateen M, Selcen D, Ohno K, Engel AG.
- Organizer
  147th American Neurology Association Annual Meeting (Poster), Chicago, IL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Soy protein β-conglycinin Attenuates Cardiac Hypertrophy and Heart Failure by Regulation of Gut Microbiota2022
- Author(s)
  Furukawa N, Kondo N, Miyazaki A, Ozeki K, Koitabashi N, Nagata K, Ohno K, Hirayama M.
- Organizer
  CVMW2022 心血管代謝週間
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Painful muscle spasm with marked hyper-creatine kinase (CK) level after more than twenty weeks of four pregnant women with myotonic dystrophy type 1 (DM1) and a pregnant woman with paramyotonia congenita (PMC)2022
- Author(s)
  Kinoshita M, Hara W, Yoshida N, Miyauchi A, Yamamoto M, Oji S, Fukaura H, Kaida K, Ohno K.
- Organizer
  13th International Myotonic Dystrophy Consortium Meeting (Poster), Osaka, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Interactions between muscle glucose homeostasis and neuromuscular signal transduction - Lessons learned from lack of a muscle-specific long isoform of GFPT1 -2022
- Author(s)
  Farshadyeganeh P, Nazim M, Ohkawara B, Masuda A, Ito M, Takeda J, Ohe K, Ohno K.
- Organizer
  European Human Genetics Conference 2022 (Platform), Vienna, Austria
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] 分子状水素はmtUPR応答を示す細胞株の増殖を促進する2022
- Author(s)
  寺西正樹, 長谷川智也, 伊藤美佳子, 西脇寛, 武田淳一, Tyler LeBaron, 大野欽司
- Organizer
  第11回日本分子状水素医学生物学会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] 超低周波微弱磁場は社会的敗北モデルマウスのうつ様症状を改善する2022
- Author(s)
  寺西正樹, 伊藤美佳子, 大野欽司
- Organizer
  第12回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Prediction of the splicing effects of SNVs affecting the first nucleotide G of an exon2021
- Author(s)
  Joudaki1 A, Takeda J, Masuda A, Ohno K
- Organizer
  European Human Genetics Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] The suppressive role for the splicing regulator, PTBP1, in the production of neuron-specific agrin isoform2021
- Author(s)
  Bushra S, Lin Y, Joudaki A, Masuda A, Ohno K
- Organizer
  American Society of Human Genetics 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Gut dysbiosis in Parkinson's disease with motor complications2021
- Author(s)
  Kai Takahashi, Hiroshi Nishiwaki, Mikako Ito, Kazuhiro Iwaoka, Kanako Yamahara, Kenta Takahashi, Yoshio Suzuki, Keita Taguchi, Yoshio Tsuboi, Kenichi Kashihara, Masaaki Hirayama, Kinji Ohno, Tetsuya Maeda
- Organizer
  MDS Virtual Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08001
[Presentation] 速筋の神経筋接合部終板における網羅的遺伝子発現解析2021
- Author(s)
  伊藤美佳子, Kun Huang, 大野欽司
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Functional analysis of mutations in a glycosylation enzyme gene, GFPT1, underlying limb-girdle congenital myasthenic syndromes (CMS)2021
- Author(s)
  Farshadyeganeh P, Ohkawara B, Kamon M, Araki T, Komaki H, Ohno K.
- Organizer
  European Human Genetics Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] 先天性筋無力症候群2021
- Author(s)
  大野欽司
- Organizer
  久留米大学小児科学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] Functional analysis of mutations in a glycosylation enzyme gene, GFPT1, underlying limb-girdle congenital myasthenic syndromes (CMS)2021
- Author(s)
  Farshadyeganeh P, Ohkawara B, Kamon M, Araki T, Komaki H, Ohno K
- Organizer
  European Human Genetics Conference 2021 (Poster), Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Gut microbiota in patients with Parkinson’s disease (PD) predicts disease progression better than clinical features2021
- Author(s)
  Hiroshi Nishiwaki, Tomonari Hamaguchi, Mikako Ito, Tetsuya Maeda, Kenichi Kashihara, Yoshio Tsuboi, Masahisa Katsuno, Masaaki Hirayama, Kinji Ohno
- Organizer
  MDS Virtual Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08001
[Presentation] Prediction of the splicing effects of SNVs affecting the first nucleotide G of an exon2021
- Author(s)
  Joudaki1 A, Takeda J, Masuda A, Ohno K.
- Organizer
  European Human Genetics Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] The suppressive role for the splicing regulator, PTBP1, in the production of neuron-specific agrin isoform2021
- Author(s)
  Bushra S, Lin Y, Joudaki A, Masuda A, Ohno K
- Organizer
  American Society of Human Genetics 2021 (Poster), Virtual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] RNA 結合タンパクMatrin3 が形成する核内顆粒による遺伝子発現制御2021
- Author(s)
  増田章男, 岡本喬明, 大野欽司
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] The suppressive role for the splicing regulator, PTBP1, in the production of neuron-specific agrin isoform2021
- Author(s)
  Bushra S, Lin Y, Joudaki A, Masuda A, Ohno K.
- Organizer
  American Society of Human Genetics 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] 速筋の神経筋接合部終板における網羅的遺伝子発現解析2021
- Author(s)
  伊藤美佳子、Kun Huang、大野欽司
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] Prediction of the splicing effects of SNVs affecting the first nucleotide G of an exon2021
- Author(s)
  Joudaki A, Takeda J, Masuda A, Ohno K
- Organizer
  European Human Genetics Conference 2021 (Poster), Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Functional analysis of mutations in a glycosylation enzyme gene, GFPT1, underlying limb-girdle congenital myasthenic syndromes (CMS)2021
- Author(s)
  Farshadyeganeh P, Ohkawara B, Kamon M, Araki T, Komaki H, Ohno K
- Organizer
  European Human Genetics Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04815
[Presentation] パーキンソン病における運動合併症と腸内細菌叢に関する研究2021
- Author(s)
  高橋海，平山正昭，坪井義夫，柏原健一，伊藤美佳子，田口啓太，鈴木啓生，高橋健太，山原可奈子，岩岡和博，大野欽司，西脇寛，前田哲也
- Organizer
  第15回パーキンソン病運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-19K08001
[Presentation] InMeRF: A set of random forest models for each amino acid substitution to predict pathogenicity of missense variants in the human genome2020
- Author(s)
  Takeda J, Nanatsue K, Yamagishi R, Ito M, Ohno K
- Organizer
  European Society of Human Genetics Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] 骨粗鬆症は変形性膝関節症の10 年間での進行に寄与するか2020
- Author(s)
  石塚真哉、今釜史郎、関泰輔、平岩秀樹、山下暁士、大野洋平、大羽宏樹、川村佑介、坂口健史、石黒直樹、長谷川幸治
- Organizer
  第93回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] 地域住民検診における肩腱板断裂と脊椎アライメントの関連2020
- Author(s)
  大羽宏樹、大野洋平、平岩秀樹、石塚真哉、山下暁士、川村佑介、小早川晃範、坂口健史、井戸田大
- Organizer
  第47回日本肩関節学会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] Promethazineは腱修復中の過剰なWntシグナルを抑制し、修復腱の力学的特性を改善した2020
- Author(s)
  坂口健史, 大河原美静, 増田章男, 伊藤美佳子, 武田淳一, 濱口知成, 今釜史郎, 平岩秀樹, 石塚真哉, 大野欽司
- Organizer
  第6回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] 無症候性腱板断裂は肩こりを高率に合併する2020
- Author(s)
  石塚真哉、今釜史郎、関泰輔、大野洋平、山下暁士、平岩秀樹、大羽宏樹、川村佑介、坂口健史、石黒直樹、長谷川幸治
- Organizer
  第93回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] Effect of zonisamide on acetylcholine receptor cluster at the neuromuscular junction2020
- Author(s)
  Inoue T, Ohkawara B, Nakashima H, Imagama S, Ishiguro N, Ohno K
- Organizer
  ORS 2020 Annual Meeting (Poster), Phoenix, Arizona, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] 無症候性腱板断裂は肩こりを高率に合併する2020
- Author(s)
  石塚真哉、平岩秀樹、山下暁士、大羽宏樹、川村佑介、坂口健史、井戸田大、羽賀貴博、水野隆文、大野洋平
- Organizer
  第47回日本肩関節学会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] InMeRF: A set of random forest models for each amino acid substitution to predict pathogenicity of missense variants in the human genome2020
- Author(s)
  Takeda J, Nanatsue K, Yamagishi R, Ito M, Ohno K
- Organizer
  European Society of Human Genetics Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03561
[Presentation] Activity of Wnt signaling in regenerated tendon and its effects on tendon repair.2020
- Author(s)
  Takefumi Sakaguchi, Bisei Ohkawara, Hideki Hiraiwa, Shinya Ishizuka, Kinji Ohno, Naoki Ishiguro
- Organizer
  ORS 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] Meclozine enhances skeletal muscle growth and improves exercise performance.2019
- Author(s)
  Yusuke Kawamura, Bisei Ohkawara, Hideki Hiraiwa, Shinya Ishizuka, Kinji Ohno, Naoki Ishiguro
- Organizer
  第5回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] 腱再生におけるwntシグナル活性の変化とそれが腱修復に与える影響2019
- Author(s)
  坂口健史,大河原美静, 岸本烈純, 宮本健太郎, 平岩秀樹, 石黒直樹, 大野欽司
- Organizer
  第34 回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells2019
- Author(s)
  Huang K, Masuda A, Ohkawara B, Ito M, Ohno K
- Organizer
  5th Annual Meeting of Japan Muscle Society (Poster), Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-19K22802
[Presentation] Clinically Feasible Dose Of Meclozine Promotes Bone Growth In Mouse Model With Achondroplasia2017
- Author(s)
  Matsushita M, Kitoh H, Mishima K, Sugiura H, Kitamura A, Ishiguro N, Ohno K
- Organizer
  ORS 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] SRSF1 suppresses selection of intron-distal 5’ splice site of DOK7 intron 4 to generate functional full-length Dok-7 protein2017
- Author(s)
  Ahsan KB, Masuda A, Rahman MA, Takeda J, Ohkawara B, Ito M, Ohno K.
- Organizer
  2017 CSHL Meeting: Eukaryotic mRNA Processing
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms2017
- Author(s)
  Nazim M, Masuda A, Rahman MA, Nasrin F, Takeda J, Ohe K, Ohkawara B, Ito M, Ohno K.
- Organizer
  2017 CSHL Meeting: Eukaryotic mRNA Processing
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] Japanese myotonic dystrophy type 2 patients carry a haplotype different from the European founder haplotype2017
- Author(s)
  Matsuura T, Kimura T, Kitao R, Komori T, Toda T, Ohno K.
- Organizer
  11th International myotonic dystrophy consortium meeting (IDMC-11)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling2017
- Author(s)
  Miyamoto K, Ohkawara B, Sakai T, Hiraiwa H, Hamada T, Ohno K, Ishiguro N
- Organizer
  ORS 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] Radical Therapeutic Strategy For Foramen Magnum Stenosis And Spinal Canal Stenosis In Achondroplasia.2016
- Author(s)
  Matsushita M, Kitoh H, Mishima K, Sugiura H, Hasegawa S, Ishiguro N, Ohno K
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  オーランド,アメリカ
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] Splicing regulation of the human acetylcholinesterase gene2016
- Author(s)
  Ohno K, Nazim M, Masuda A.
- Organizer
  XVth International Symposium on Cholinergic Mechanisms
- Place of Presentation
  Marseille, France
- Year and Date
  2016-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] Radical Therapeutic Strategy For Foramen Magnum Stenosis And Spinal Canal Stenosis In Achondroplasia.2016
- Author(s)
  Matsushita M, Kitoh H, Mishima K, Sugiura H, Hasegawa S, Ishiguro N, Ohno K
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  オーランド、アメリカ
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Roles of collagen Q in MuSK antibody‐positive myasthenia gravis2015
- Author(s)
  Ohno K
- Organizer
  12th International Meeting of Cholinesterases
- Place of Presentation
  Alicante (Spain)
- Year and Date
  2015-09-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] LGI2 heterozygous variant identified in a Japanese family with autosomal dominant cryptogenic West syndrome2015
- Author(s)
  Ishihara N, Azuma Y, Nakata T, Takeuchi T, Okuno T, Ohno K, J Natsume J
- Organizer
  American Society for Human Genetics 2015
- Place of Presentation
  Baltimore, MD, USA
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461542
[Presentation] スプライシングシス因子の破綻によるスプライシング異常の分子機構とその予測ツール2015
- Author(s)
  大野欽司
- Organizer
  第38回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118508
[Presentation] スプライシングシス因子の破綻によるスプライシング異常の分子機構とその予測ツール2015
- Author(s)
  大野欽司
- Organizer
  第38回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(神戸市中央区)
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] 軟骨細胞におけるSOX9発現を促進させる既存薬の検索2015
- Author(s)
  長谷川幸,鬼頭浩史,三島健一,松下雅樹,杉浦洋,北村暁子,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Meclozineは軟骨無形成症における大後頭孔および脊柱管狭窄を改善しうる2015
- Author(s)
  松下雅樹,鬼頭浩史,三島健一,杉浦洋,長谷川幸,北村暁子,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Meclozineは軟骨無形成症における大後頭孔および脊柱管狭窄を改善しうる2015
- Author(s)
  松下雅樹,鬼頭浩史,三島健一,杉浦洋,長谷川幸,北村暁子,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] 骨芽細胞におけるFGF23の発現を抑制する既存薬の検索2015
- Author(s)
  杉浦洋,鬼頭浩史,三島健一,松下雅樹,長谷川幸,北村暁子,大河原美静,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] 骨芽細胞におけるFGF23の発現を抑制する既存薬の検索2015
- Author(s)
  杉浦洋,鬼頭浩史,三島健一,松下雅樹,長谷川幸,北村暁子,大河原美静,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] 軟骨無形成症における根本的治療薬の開発2015
- Author(s)
  松下雅樹,鬼頭浩史,三島健一,杉浦洋,長谷川幸,北村暁子,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] LRP4 Myasthenia. Investigation of second kinship reveals impaired development and maintenance of the neuromuscular junction2015
- Author(s)
  Selcen D, Ohkawara B, Shen X-M, McEvoy K, Ohno K, Engel AG
- Organizer
  WMS Congress [Neuromuscular Disorders 25: ( Suppl 2) : S186-S187]
- Place of Presentation
  Brighton (UK)
- Year and Date
  2015-09-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] 軟骨細胞におけるSOX9発現を促進させる既存薬の検索2015
- Author(s)
  長谷川幸,鬼頭浩史,三島健一,松下雅樹,杉浦洋,北村暁子,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] 筋チャネル病‐周期性四肢麻痺および非ジストロフィー性ミオトニー症候群の遺伝子解析と麻痺発作重症度分類2015
- Author(s)
  高橋正紀、佐々木良元、久保田智哉、穀内洋介、古田充、中森雅之、望月秀樹、冨本秀和、大野欽司
- Organizer
  第1回日本筋学会学術集会
- Place of Presentation
  国立精神・神経医療研究センター（東京都小平市）
- Year and Date
  2015-08-07
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] 軟骨無形成症における根本的治療薬の開発2015
- Author(s)
  松下雅樹,鬼頭浩史,三島健一,杉浦洋,長谷川幸,北村暁子,西田佳弘,石黒直樹,大野欽司
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場、ＡＮＡクラウンプラザホテル富山、富山市民プラザ（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] 教育講演「神経疾患とRNA代謝：治療への展望」2015
- Author(s)
  大野欽司
- Organizer
  第33回日本神経治療学会総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-11-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118508
[Presentation] コンジェニックマウスを用いた食餌誘導性脂肪肝感受性遺伝子の存在領域の解析2015
- Author(s)
  鈴木京、小林美里、大野民生、辻村絢子、村井篤嗣、堀尾文彦
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-24380068
[Presentation] 神経疾患関連RNA結合蛋白FUSによる転写開始・終結制御2015
- Author(s)
  増田章男、武田淳一、大野欽司
- Organizer
  第17回日本RNA学会年会
- Place of Presentation
  ホテルライフォート札幌（北海道札幌市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PUBLICLY-25118508
[Presentation] Physiology and hereditary/autoimmune pathology of acetylcholine receptor clustering at the neuromuscular junction2015
- Author(s)
  Ohno K
- Organizer
  10th Japanese-French Workshop“New advances in treatments of neuromuscular diseases: From Basic to Applied Myology”
- Place of Presentation
  Paris (France)
- Year and Date
  2015-07-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] Schwartz-Jampel 症候群を引き起こすHSPG2 (パールカン)の遺伝子変異2015
- Author(s)
  伊藤美佳子、岩田哲、中田智彦、野口陽一朗、奥野達矢、大河原美静、増田章男、後藤知英、安達昌功、小坂仁、野中里紗、平澤恵理、大野欽司
- Organizer
  第1回日本筋学会学術集会
- Place of Presentation
  国立精神・神経医療研究センター（東京都小平市）
- Year and Date
  2015-08-07
- Data Source
  KAKENHI-PROJECT-15H04840
[Presentation] 乗り物酔い止めOTC薬meclozineはFGFR3シグナルを抑制して軟骨無形成症の低身長をレスキューする2014
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、石黒直樹、大野欽司
- Organizer
  第32回小児代謝性骨疾患研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] 乗り物酔い止めOTC薬meclozineはFGFR3シグナルを抑制して軟骨無形成症の低身長をレスキューする2014
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、石黒直樹、大野欽司
- Organizer
  第32回小児代謝性骨疾患研究会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Maintenance of the neuromuscular junction and its aberrations in hereditary and autoimmune disorders2014
- Author(s)
  Ohno K
- Organizer
  Guarda-Symposium 2014 on the Molecular and Cell Biology of the Neuromuscular System
- Place of Presentation
  Guarda, Switzerland
- Year and Date
  2014-09-01
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] 脂肪肝感受性遺伝子座（Fl1sa）の候補遺伝子の発現制御機構の解析とコンジェニックマウスによる責任遺伝子の探索2014
- Author(s)
  鈴木　京、小林美里、大野民生、辻村絢子、小田裕昭、村井篤嗣、堀尾文彦
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  江別
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-24380068
[Presentation] Investigation of 11 patients with GFPT1-myasthenia reveals clinical, structural, and electrophysiologic heterogeneity2013
- Author(s)
  Selcen D, Shen X-M, Milone M, Brengman J, Ohno K, McQuillen M, Deymeer F, Finkel R, Rowin J, Engel AG
- Organizer
  65th American Academy of Neurology (Platform)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] 脂肪肝感受性を規定する候補遺伝子の肝細胞脂質代謝に対する作用の解析2013
- Author(s)
  都築佳奈、小林美里、鈴木京、大野民生、村井篤嗣、堀尾文彦
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-24380068
[Presentation] Mutations in the third β-propeller domain of LRP4 in congenital myasthenia compromise agrin-mediated MuSK signaling in a position-specific manner2013
- Author(s)
  Ohkawara B, Cabrera M, Nakata T, Milone M, Ito Y, Engel AG, Ohno K
- Organizer
  36th Annual Meeting of the Japan Neuroscience Society (Poster)
- Place of Presentation
  国立京都国際会館 (京都市 )
- Year and Date
  2013-06-22
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] Symposium : Molecular mechanisms of oxidative stress resistance induced by a new gas mediator : Molecular mechanism of the inhibitory effect of hydrogen on inflammation.2013
- Author(s)
  Ito M, Itoh T, Ohno K, Nozawa Y.
- Organizer
  90^<th> Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] Mutations in the third β-propeller domain of LRP4 in congenital myasthenia compromise agrin-mediated MuSK signaling in a position-specific manner2013
- Author(s)
  Ohkawara B, Cabrera M, Nakata T, Milone M, Ito Y, Engel AG, Ohno K
- Organizer
  36th Annual Meeting of the Japan Neuroscience Society (Poster)
- Place of Presentation
  国立京都国際会館(京都市)
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] R-spondin2 is crucial for neuromuscular junction formation2013
- Author(s)
  Nakashima H, Ohkawara B, Imagama S, Ito Z, Ishiguro N, Ohno K
- Organizer
  43rd Annual Meeting, Society for Neuroscience (Poster)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Investigation of 11 Patients with GFPT1-Myasthenia Reveals Clinical, Structural, and Electrophysiologic Heterogeneity2013
- Author(s)
  Selcen D, Shen X-M, Milone M, Brengman J, Ohno K, McQuillen M, Deymeer F, Finkel R, Rowin J, Engel AG
- Organizer
  65th American Academy of Neurology (Platform)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Potential clinical application of meclizine, an anti-histamine drug, for short stature in FGFR3-related skeletal dysplasias.2013
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Hiroshi Kaneko, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno.
- Organizer
  第24回日本小児整形外科学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Collagen Q is a key player for developing rational therapy for congenital myasthenia and for causing anti-MuSK myasthenia gravis2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Ohtsuka K, Krejci E
- Organizer
  XIV International Symposium on Cholinergic Mechanisms (Invited Platform)
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] Mutations in the third β-propeller domain of LRP4 in congenital myasthenia compromise agrin-mediated MuSK signaling in a position-specific manner2013
- Author(s)
  Ohkawara B, Cabrera M, Nakata T, Milone M, Ito Y, Engel AG, Ohno K
- Organizer
  36th Annual Meeting of the Japan Neuroscience Society (Poster)
- Place of Presentation
  国立京都国際会館(京都市)
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Molecular mechanism of the inhibitory effect of hydrogen on inflammation2013
- Author(s)
  Ito M, Itoh T, Ohno K, Nozawa Y
- Organizer
  90th Annual Meeting of the Physiological Society of Japan (Platform)
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Alternative RNA splicing regulating the molecular architecture of NMJ2013
- Author(s)
  Nasrin F, Rahman MA, Ohe K, Masuda A, Ohno K
- Organizer
  5th NAGOYA Global Retreat (Poster)
- Place of Presentation
  あいち健康プラザ（名古屋市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Meclozineは軟骨無形成症におけるFGFR3シグナルによる軟骨細胞の増殖・分化抑制をレスキューする.2013
- Author(s)
  松下雅樹、鬼頭浩史、金子浩史、三島健一、石黒直樹、大野欽司.
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ国際会議場（千葉市）
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] RNA diseases caused by defects in cis-acting elements and trans-acting factors2013
- Author(s)
  Ohno K
- Organizer
  "Danish-Japanese joint seminar on aberrant RNA splicing in neuromuscular disease", Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU)
- Place of Presentation
  Odense, Denmark
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Collagen Q is a key player for developing rational therapy for congenital myasthenia and for causing anti-MuSK myasthenia gravis2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Ohtsuka K, Krejci E.
- Organizer
  XIV International Symposium on Cholinergic Mechanisms (Platform)
- Place of Presentation
  Hangzhou, China
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Collagen Q is a key player for developing rational therapy for congenital myasthenia and for causing anti-MuSK myasthenia gravis2013
- Author(s)
  Ohno K, Ito M, Kawakami Y, Ohtsuka K, Krejci E.
- Organizer
  XIV International Symposium on Cholinergic Mechanisms (Platform)
- Place of Presentation
  Hangzhou, China
- Invited
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] Mutations in LRP4 in congenital myasthenia reveal position-specific regulations of agrin and Wnt signaling of LPR42013
- Author(s)
  Ohkawara B, Cabrera M, Nakata T, Shen X, Ito Y, Engel AG, Ohno K
- Organizer
  43rd Annual Meeting, Society for Neuroscience (Poster)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] Meclozine facilitates chondrocyte proliferation and differentiation by attenuating abnormally activated fibroblast growth factor receptor 3 (FGFR3) signaling in achondroplasia.2013
- Author(s)
  Masaki Matsushita, Hiroshi Kitoh, Hiroshi Kaneko, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno.
- Organizer
  International Skeletal Dysplasia Meeting
- Place of Presentation
  Bologna(Italy)
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Molecular mechanism of the inhibitory effect of hydrogen on inflammation2013
- Author(s)
  Ito M, Itoh T, Ohno K, Nozawa Y
- Organizer
  90th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] Mutations in LRP4 in congenital myasthenia reveal position-specific regulations of agrin and Wnt signaling of LPR42013
- Author(s)
  Ohkawara B, Cabrera M, Nakata T, Shen X, Ito Y, Engel AG, Ohno K
- Organizer
  43rd Annual Meeting, Society for Neuroscience (Poster)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Mutations in LRP4 in congenital myasthenia reveal position-specific regulations of agrin and Wnt signaling of LPR42013
- Author(s)
  Ohkawara B, Cabrera M, Nakata T, Shen X, Ito Y, Engel AG, Ohno K
- Organizer
  43rd Annual Meeting Society for Neuroscience (Poster)
- Place of Presentation
  San Diego, USA
- Year and Date
  2013-11-13
- Data Source
  KAKENHI-PROJECT-25670164
[Presentation] Mutation in congenital myasthenic syndrome reveals opposite splicing regulatory effects of hnRNPs L and LL2012
- Author(s)
  Rahman MA, Ohe K, Masuda A, Ito M, Hutchinson DO, Engel AG, Ohno K
- Organizer
  35th Annual Meeting of the Japan Neuroscience Society (Poster)
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Functional characterization of GFPT1 during myogenesis and NMJ formation2012
- Author(s)
  Ohkawara B, Fuse Y, Nakashima H, Ohno K
- Organizer
  The 11th Annual Scientific Meeting of the Asian and Oceanian Myology Center (Poster)
- Place of Presentation
  京都市芝蘭会館（京都市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] 軟骨細胞におけるFGFR3シグナルを抑制する既存薬の検索2012
- Author(s)
  松下雅樹、鬼頭浩史、金子浩史、三島健一、石黒直樹、大野欽司
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Global mapping and global expression profiling of RNA-binding proteins that are associated with neurological and neuromuscular diseases2012
- Author(s)
  Ohno K
- Organizer
  35th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] 分子状水素はシグナル伝達の抑制を介してLPS/IFN-γにより誘導されるNOの産生を抑制する2012
- Author(s)
  伊藤雅史、伊藤智広、伊藤美佳子、大野欽司、野澤義則
- Organizer
  第2回分子状水素医学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] RNA-mediated disease mechanism of spinocerebellar ataxia type 10.2012
- Author(s)
  Matsuura T, Kurosaki T, Muramatsu S, Shimazaki K, Ohno K, Abe K.
- Organizer
  7th International Conference on Unstable Microsatellites & Human Disease
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PROJECT-24390083
[Presentation] Global analysis of RNA-binding sites of CUGBP1 and MBNL1 reveal their preferential binding to 3’ UTRs to regulate mRNA stability2012
- Author(s)
  Masuda A, Andersen HS, Doktor TK, Okamoto T, Ito I, Andresen BS, Ohno K
- Organizer
  The 11th Annual Scientific Meeting of the Asian and Oceanian Myology Center (Poster)
- Place of Presentation
  京都市芝蘭会館（京都市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Global mapping of FUS-binding sites and global profiling of FUS-mediated RNA metabolisms in the mouse brain2012
- Author(s)
  Masuda A, Ishigaki S, Fujioka Y, Iguchi Y, Katsuno M, Shibata A, Urano F, Sobue G, Ohno K
- Organizer
  62nd Annual Meeting of the American Society of Human Genetics (Poster)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Congenital defects of neuromuscular signal transduction2012
- Author(s)
  Ohno K
- Organizer
  3rd Berlin Summer School for Myology
- Place of Presentation
  Berlin, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] In myotonic dystrophy type 1 Peroxiredoxin-2 of RBC membrane protein was reduced, compared with a normal subject2012
- Author(s)
  Kinoshita M, Morita S, Ohno K, Hirose K
- Organizer
  The 11th Annual Scientific Meeting of the Asian and Oceanian Myology Center (Poster)
- Place of Presentation
  京都市芝蘭会館（京都市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] A comprehensive and efficient algorithm to predict splicing consequences of intronic nucleotide substitutions in the human genome2012
- Author(s)
  Shibata A, Masuda A, Ohno K
- Organizer
  62nd Annual Meeting of the American Society of Human Genetics (Poster)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis2012
- Author(s)
  Ohno K
- Organizer
  11th International Meeting on Cholinesterases
- Place of Presentation
  Kazan, Russia
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Congenital defects of neuromuscular signal transduction2012
- Author(s)
  Ohno K
- Organizer
  3rd Berlin Summer School for Myology
- Place of Presentation
  Berlin, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Molecular hydrogen alters signaling pathways and gene expression profiles in multiple mouse organs2012
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Ohkuwa T, Ichihara M
- Organizer
  52nd Annual Meeting of the American Society for Cell Biology (Poster)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Molecular bases and therapeutic intervention of neuromuscular transmission defects2012
- Author(s)
  Ohno K
- Organizer
  Ninth French-Japanese Workshop on Muscular Dystrophies
- Place of Presentation
  ＪＡ共済ビルカンファレンス・ホール（東京都千代田区）
- Invited
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Molecular hydrogen alters signaling pathways and gene expression profiles in multiple mouse organs.2012
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Ohkuwa T, Ichihara M.
- Organizer
  52nd Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, USA.
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] Molecular hydrogen alters signaling pathways and gene expression profiles in multiple mouse organs2012
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Ohkuwa T, Ichihara M
- Organizer
  American Society for Cell Biology, Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] EMG findings at non-myotonia and myotonia states in patients with Na channelopathies2012
- Author(s)
  Kinoshita M, Kokunai Y, Kubota T, Takahashi M, Sasaki R, Ohno K, Hirose K
- Organizer
  The 11th Annual Scientific Meeting of the Asian and Oceanian Myology Center (Poster)
- Place of Presentation
  京都市芝蘭会館（京都市）
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Protein-anchoring therapy for delivering acetylcholinesterase to theneuromuscular junction2011
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  4th International Congress of Myology
- Place of Presentation
  Lille, France
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] 筋疾患における水素水経口投与の臨床効果2011
- Author(s)
  衣斐達、佐橋功、大野欽司、小澤史子、伊藤雅史
- Organizer
  分子状水素医学シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] Protein-anchoring therapy for delivering acetylcholinesterase to the neuromuscular junction2011
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  4th International Congress of Myology
- Place of Presentation
  Lille, France(招待講演)
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Anti-MuSK antibodies in myasthenia gravis block binding of collagen Q to MuSK expressed at the neuromuscular junction2011
- Author(s)
  Kawakami Y, Ito M, Hirayama M, Sahashi K, Ohkawara B, Masuda A, Hishida H, Mabuchi N, Engel AG, Ohno K
- Organizer
  41st Annual Meeting, Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] 分子状水素による炎症反応抑制の分子機構2011
- Author(s)
  伊藤雅史、伊藤智広、伊藤美佳子、大野欽司、野澤義則
- Organizer
  第34回日本基礎老化学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] 水素水飲用をシュミレーションする水素ガス間欠投与は水素ガス持続投与よりもパーキンソンモデルラットに対して有効である2011
- Author(s)
  伊藤美佳子、市原正智、伊藤雅史、大野欽司
- Organizer
  第2回分子状水素医学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-02-11
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] Mutations at the C-terminal domain(CTD) of collagen Q(ColQ) causingacetylcholinesterase(AChE) deficiencyprevent anchoring of ColQ to theneuromuscular junction(NMJ)2010
- Author(s)
  Sugiyama A, Ito M, Nakata T, Azuma Y, Masuda A, Okumura A, Komaki H, Ohno K
- Organizer
  Mutations at the C-terminal domain(CTD) of collagen Q(ColQ) causingacetylcholinesterase(AChE) deficiencyprevent anchoring of ColQ to theneuromuscular junction(NMJ)
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] 分子状水素による1型アレルギー抑制機構0)解明2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] ワークショップ:水素医学の展開:分子状水素による細胞内シグナル伝達の調節2010
- Author(s)
  伊藤雅史、伊藤智広、野澤義則、伊藤美佳子、大野欽司
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] rAAV8-Mediated Protein-Anchoring Therapy for Targeting Collagen Q-Tailed Acetylcholinesterase to the Neuromuscular Junction2010
- Author(s)
  Ito M, Suzuki Y, Okada T, FukudomeT, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  American Society of Gene & Cell Therapy 13th Annual Meeting, Washington DC
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] 分子状水素によるI型アレルギー抑制機構の解明2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  日本基礎老化学会第33回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 分子状水素によるI型アレルギー抑制の分子機構2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  第130回日本薬学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 分子状水素によるI 型アレルギー抑制機構の解明2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] Mutations at the C-terminal domain (CTD) of collagen Q (ColQ) causing acetylcholinesterase (AChE) deficiency prevent anchoring of ColQ to the neuromuscular junction (NMJ)2010
- Author(s)
  Sugiyama A, Ito M, Nakata T, Azuma Y, Masuda A, Okumura A, Komaki H, Ohno K
- Organizer
  40th Annual Meeting, Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] 水素医学の展開 : 分子状水素による細胞内シグナル伝達の調節2010
- Author(s)
  伊藤雅史、伊藤智広、野澤義則、伊藤美佳子、大野欽司
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22300244
[Presentation] rAAV8-Mediated Protein-Anchoring Therapy for Targeting Collagen Q-Tailed Acetylcholinesterase to the Neuromuscular Junction2010
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Masuda A, Takeda S, Krejci E, Ohno K
- Organizer
  American Society of Gene & Cell Therapy 13th Annual Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] A mutation on a nonfunctional exon P3A inCHRNA1 identified in a patient withcongenital myasthenic syndrome losesbinding affinity for a splicing-suppressinghn RNP L and gains binding affinity for asplicing-enhancing RNP LL2009
- Author(s)
  Rahman MA, Masuda A, Ito M, Ohno K
- Organizer
  2nd GCOE International Symposium
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Degeneracy of splicing cis-elements and tolerance to disease-causing mutations2009
- Author(s)
  Ohno K
- Organizer
  2nd GCOE International Symposium
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Molecular mechanisms and regulations of congenital neuromuscular transmission defects2009
- Author(s)
  Ohno K
- Organizer
  Universite Paris Descartes Seminaire
- Place of Presentation
  Paris, France
- Year and Date
  2009-07-06
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] Protein anchoring therapy for endplateacetylcholinesterase deficiency2009
- Author(s)
  Ohno K, Ito M, Suzuki Y, Okada T, Fukudome T, Yoshimura T, Takeda S, Krejci E
- Organizer
  Eighth French-Japanese Workshop on Muscular Dystrophies
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] AG-independence of the 3'splice site determines tolerance to aberrant splicingdue to a mutation at the first nucleotide of an exon2009
- Author(s)
  Fu Y, Masuda A, Ito M, Ohno K
- Organizer
  2nd GCOE International Symposium
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-21390266
[Presentation] CMS due to Defects in Rapsyn: Clinical and Molecular Findings of a Large Cohort2008
- Author(s)
  Milone M, Shen X-M, Selcen D, Ohno K, Brengman JM, Iannaccone S, Engel AG
- Organizer
  55th Annual Meeting of the American Association of Neuromuscular and Electrodiagnostic medicine
- Place of Presentation
  Rhode Island, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Adeno-associated virus serotype 8-mediated targeting of asymmetric acetylcholinesterase to the synaptic basal lamina at the neuromuscular junction.2008
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Masuda A, Yoshimura T, Takeda S, Krejci E, Ohno K.
- Organizer
  The 38th Annual Meeting, Society for Neuroscience.
- Place of Presentation
  Washington D. C., USA
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] CMS due to defects in rapsyn: clinical and molecular findings of a large cohort2008
- Author(s)
  Milone M, Shen X-M, Selcen D, Ohno K, Brengman JM, Iannaccone S, Engel AG
- Organizer
  12th Congress of the European Federation of Neurological Societies
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Recombinant extracellular matrix protein expressed in a limited number of cells propagates to the target organ throughout the body using its nascent tissue-targeting signal2008
- Author(s)
  Suzuki Y, Ito M, Okada T, Takeda S, Fukudome T, Yoshimura T, Krejci E, Ohno K
- Organizer
  13th Congress of the International Federation of Societies for Histochemistry and Cytochemistry
- Place of Presentation
  Gdansk, Poland
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] rAAV8-mediated protein anchoring of asymmetric acetylcholinesterase (AChE) to the synaptic basal lamina at the neuromuscular junction (NMJ)2008
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Masuda A, Yoshimura T, Takeda S, Krejci E, Ohno K
- Organizer
  48th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Adeno-associated virus serotype 8-mediated targeting of asymmetric acetylcholinesterase to the synaptic basal lamina at the neuromuscular junction2008
- Author(s)
  Ito M, Suzuki Y, Okada T, Fukudome T, Masuda A, Yoshimura T, Takeda S, Krejci E, Ohno K
- Organizer
  38th Annual Meeting, Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Myotonic dystrophy type 2 in Japan: distinct ancestral origin from Caucasian familiesne2007
- Author(s)
  Amakusa Y, Matsuura T, Saito T, Kimura T, Yahara O, Aizawa H, Ikeda Y, Day JW, Ranum LPW, Ohno K
- Organizer
  57th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Unstable siRNA duplex is a prerequisite for accurate prediction of siRNA efficiency-Proposal of a new parameter based on the linear regression model2007
- Author(s)
  Ohno K, Ichihara M
- Organizer
  57th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Unstable siRNA duplex is a prerequisite for accurate prediction of siRNA efficiency-Proposal of a new parameter based on the linear regression model-2007
- Author(s)
  Ohno K
- Organizer
  57th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-18016011
[Presentation] Unstable siRNA duplex is a prerequisite for accurate prediction of siRNA efficiency-Proposal of a new parameter based on the linear regression model-2007
- Author(s)
  Ohno K
- Organizer
  57th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Gene Therapy for Collagen Q defects in congenital myasthenic syndromes2007
- Author(s)
  Ito M, Masuda A, Jinno S, Katagiri T, Krejci E, Ohno K
- Organizer
  The IXth International Meeting on Cholinesterases
- Place of Presentation
  Shuzou, China
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Comprehensive analysis of aberrantly spliced exons in myotonic dystrophy type 1 using Affymetrix Exon Array2007
- Author(s)
  Yamashita Y, Matsuura T, Shinmi J, Ibi T, Kinoshita M, Kimura T, Yahara O, Sahashi K, Ohno K
- Organizer
  57th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-19390237
[Presentation] Meclozine enhances skeletal growth in transgenic achondroplasia mice with a constitutive active FGFR3 mutation
- Author(s)
  Matsushita, Masaki; Kitoh, Hiroshi; Kenichi Mishima; Ishiguro Naoki; Ohno Kinji
- Organizer
  2015 Annual Meeting - Orthopaedic Research Society
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Wnt/β-カテニンシグナル制御を介した変形性関節症治療薬の探索
- Author(s)
  宮本健太郎、大河原美静、酒井忠博、高松晃、石黒直樹、大野欽司
- Organizer
  第28回日本軟骨代謝学会
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] Global identification of binding sites for the splicing regulatory factors SRSF5 and hnRNPA1
- Author(s)
  Bruun GH, Doktor TK, Broener S, Masuda A, Palhais B, Krainer AR, Ohno K, Andresen BS
- Organizer
  64th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PUBLICLY-25118508
[Presentation] meclozineはオフラベル効能によりFGFR3シグナルを抑制し軟骨無形成症の根本的治療薬となりうる
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、西田佳弘、石黒直樹、大野欽司
- Organizer
  第28回日本軟骨代謝学会
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] マウス第12番染色体の脂肪肝感受性遺伝子座に存在する遺伝子のエクソーム解析
- Author(s)
  小林美里、立石壮志、鈴木　京、大野民生、大野欽司、伊藤美佳子、村井篤嗣、堀尾文彦
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24380068
[Presentation] Meclozine enhances skeletal growth in transgenic achondroplasia mice with a constitutive active FGFR3 mutation
- Author(s)
  Matsushita, Masaki; Kitoh, Hiroshi; Kenichi Mishima; Ishiguro Naoki; Ohno Kinji
- Organizer
  2015 Annual Meeting - Orthopaedic Research Society
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] IntSplice: A tool to predict aberrant splicing of an SNV at intronic positions -50 to -3
- Author(s)
  Ohno K, Shibata A, Okuno T, Rahman MA, Azuma Y, Masuda A
- Organizer
  64th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PUBLICLY-25118508
[Presentation] Alternative splicing of human MUSK exon 10 is physiologically regulated by multiple splicing regulatory cis-elements and cognate trans-factors
- Author(s)
  Rahman MA, Masuda A, Takeda J, Ohno K
- Organizer
  RNA Biology meeting, Cold Spring Harbor Asia Conference
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-11-10 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24390221
[Presentation] Wnt/β-カテニンシグナル制御を介した変形性関節症治療薬の探索
- Author(s)
  宮本健太郎、大河原美静、酒井忠博、高松晃、石黒直樹、大野欽司
- Organizer
  第28回日本軟骨代謝学会
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-26670660
[Presentation] meclozineはオフラベル効能によりFGFR3シグナルを抑制し軟骨無形成症の根本的治療薬となりうる
- Author(s)
  松下雅樹、鬼頭浩史、三島健一、西田佳弘、石黒直樹、大野欽司
- Organizer
  第28回日本軟骨代謝学会
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-24249076
[Presentation] IntSplice: A tool to predict aberrant splicing of an SNV at intronic positions -50 to -3
- Author(s)
  Ohno K, Shibata A, Okuno T, Rahman MA, Azuma Y, Masuda A
- Organizer
  64th Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-24390221

1. MASUDA Akio (10343203)

# of Collaborated Projects: 7 results

# of Collaborated Products: 72 results
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# of Collaborated Products: 40 results
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# of Collaborated Projects: 4 results

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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 和氣弘明 (90455220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
51. ITO kengo

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# of Collaborated Products: 1 results
52. WATANABE Hirohisa

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# of Collaborated Products: 1 results
53. OHNO Mutsuhito

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# of Collaborated Products: 1 results
54. IGUCHI Akira

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# of Collaborated Products: 1 results
55. YAMASHITA Satoshi

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# of Collaborated Products: 1 results
56. Yamazaki Kazuhisa

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# of Collaborated Products: 1 results
57. TAKAHASHI Masanori

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# of Collaborated Products: 2 results
58. IKUTA Kunihiro

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59. 祖父江元

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# of Collaborated Products: 3 results
60. 飯田慶

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61. 豊國伸哉

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62. 土田邦博

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63. 加藤大輔

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64. 大野伸彦

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65. 竹田育子

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66. 奥村彰久

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67. 倉橋宏和

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68. 石垣診祐

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69. 松下雅樹

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70. 神谷庸成

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71. 飯尾明夫

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72. 多部田康一

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73. 高橋直紀

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74. 黒柳秀人

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# of Collaborated Products: 1 results
75. 中谷直史

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# of Collaborated Products: 1 results
76. 小池宏

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77. 伊藤鑑

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# of Collaborated Products: 1 results
78. 酒井智久

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# of Collaborated Products: 1 results
79. 山下由莉

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80. 石田貴文

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# of Collaborated Products: 1 results

Ohno Kinji 大野 欽司

OHNO Kinji 大野 欽司

大野 欽次 オオノ キンジ

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Investigation of the molecular formations and the pathomechanisms of the neuromuscular junctionPrincipal Investigator

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Elucidation of molecular mechanisms and application to morbidities of mitochondrial neogenesis induced extremely low frequency weak electromagnetic fieldsPrincipal Investigator

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Elucidation of molecular mechanisms of neuromuscular junction formations in physiology and pathologyPrincipal Investigator

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Elucidation of molecular mechanisms of defective neuromuscular signal transmission as a primary cause of sarcopeniaPrincipal Investigator

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Elucidation of molecular architecture of neuromuscular junction and dissection of molecular pathomechanisms of congenital myasthenic syndromesPrincipal Investigator

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神経変性疾患関連RNA結合タンパクFUSによる転写抑制機構解明Principal Investigator

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Molecular dissection of LPR4, a molecule expressed at the neuromuscular junctionPrincipal Investigator

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Ohno Kinji 大野欽司

OHNO Kinji 大野欽司

大野欽次オオノキンジ