Nishiya Tadashi 西屋禎

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NISHIYA Tadashi 西屋禎

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Researcher Number	80399831
Other IDs
Affiliation (Current)	2025: 奥羽大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2016: 奥羽大学, 薬学部, 教授 2011 – 2013: 岡山大学, 医歯(薬)学総合研究科, 准教授 2011 – 2012: 岡山大学, 大学院・医歯薬学総合研究科, 准教授 2007 – 2011: 北海道大学, 大学院・医学研究科, 講師 2006: 北海道大学, 大学院医学研究科, 講師
Review Section/Research Field	Principal Investigator Biological pharmacy Except Principal Investigator General pharmacology / Biological Sciences
Keywords	Principal Investigator ユビキチン化 / SPSB / iNOS / タンパク質分解 / ECS(SPSB) / CTTNBP2 / FOG-2 / CDC14A / 蛋白質分解 / NQO1 … More / SPSB3 / Nrf3 / ECS(SPSB3) / ECS(SPSB1/2/4) / トランスジェニックマウス / E3 / S-ニトロシル化 / SSB / ubiquitination / 敗血症 … More Except Principal Investigator ユビキチン / Jab1 / ユビキチン化 / 蛋白質分解 / エンドセリン受容体 / 酵母ツーハイブリッド法 / リン酸化 / 細胞内移行 / エンドセリン / trafficking / タンパク質分解 / 受容体結合タンパク質 / 酸化部位 / スクリーニング / 質量分析 / 細胞死 / 基質 / ストレス / リガーゼ / 小胞体 / Akt / PTEN / プロテアソーム / S-ニトロシル化 / シグナル伝達 / 神経変性疾患 / アポトーシス / 神経細胞 / 酸化ストレス / 一酸化窒素 / タンパク質間相互作用 / 蛋白質間相互作用 / エンドセリンA型受容体 / Jab 1 Less

Elucidation of the physiological function of novel E3 ubiquitin ligase that induces the inactivation of constitutively active proteins by the proteasome-dependent degradationPrincipal Investigator
- Principal Investigator
  
  Nishiya Tadashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Ohu University
Elucidation of the physiological function of iNOS degradation system by generating mice in which the SPSB inhibitor is expressed throughout the bodyPrincipal Investigator
- Principal Investigator
  
  NISHIYA Tadashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Study of the regulatory mechanism of ETAR and ETBR level by receptor binding protein and the relevance between clinical significance and endothelin receptor level.
- Principal Investigator
  
  MIWA Soichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hokkaido University
Molecular mechanism of nitric oxide/nitrosative stress implicating in onset of neurodegenerative disorders
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
  Hokkaido University
The identification and characterization of proteins that are S-nitrosylated during bacterial infection and sepsisPrincipal Investigator
- Principal Investigator
  
  NISHIYA Tadashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Search for novel signal molecules which are directly activated by endothelin receptor
- Principal Investigator
  
  MIWA Soichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hokkaido University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] SIGNALING BY TOLL-LIKE RECEPTORS2008
- Author(s)
  Tadashi Nishiya
- Publisher
  CRC Press Taylor & Francis group
- Data Source
  KAKENHI-PROJECT-20590052
[Journal Article] Correlation Between Attenuation of Protein Disulfide Isomerase Activity Through S-Mercuration and Neurotoxicity Induced by Methylmercury.2015
- Author(s)
  Makino K, Okuda K, Sugino E, Nishiya T, Toyama T, Iwawaki T, Fujimura M, Kumagai Y, Uehara T.
- Journal Title
  
  Neurotox Res
  
  Volume: 27 Issue: 2 Pages: 99-105
- DOI
  10.1007/s12640-014-9494-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03394, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25670029, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26460068
[Journal Article] NKG2D+ IFN-γ+ CD8+ T cells are responsible for palladium allergy.2014
- Author(s)
  Kawano M, Nakayama M, Aoshima Y, Nakamura K, Ono M, Nishiya T, Nakamura S, Takeda Y, Dobashi A, Takahashi A, Endo M, Ito A, Ueda K, Sato N, Higuchi S, Kondo T, Hashimoto S, Watanabe M, Watanabe M, Takahashi T, Sasaki K, Nakamura M, Sasazuki T, Narushima T, Suzuki R, Ogasawara K.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 2 Pages: 1-12
- DOI
  10.1371/journal.pone.0086810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390439, KAKENHI-PROJECT-23590066, KAKENHI-PROJECT-24590158, KAKENHI-PROJECT-24592777, KAKENHI-PROJECT-24592860, KAKENHI-PROJECT-24656430, KAKENHI-PROJECT-24791996, KAKENHI-PUBLICLY-25118703, KAKENHI-PROJECT-25249094, KAKENHI-PROJECT-25871220, KAKENHI-PROJECT-23592995
[Journal Article] Function and regulation of endothelin type A receptor-operated TRPC channels2012
- Author(s)
  Horinouchi T., Terada K., Higa T., Aoyagi H., Nishiya T., Suzuki H. and Miwa S.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 340 Pages: 143-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Adenylate cyclase-cAMP-protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca^<2+> entry mediated via TRPC6 channels2012
- Author(s)
  Horinouchi T, Higa T, Aoyagi H, Nishiya T, Terada K, Miwa S.
- Journal Title
  
  J. Phar macol. Exp. Ther
  
  Volume: 340(1) Pages: 143-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Journal Article] Nicotine- and Tar-Free Cigarette Smoke Induces Cell Damage Through Reactive Oxygen Species Newly Generated by PKC-Dependent Activation of NADPH Oxidase2012
- Author(s)
  Asano H, Horinouchi T, Mai Y, Sawada O, Fujii S, Nishiya T, Minami M, Katayama T, Iwanaga T, Terada K, Miwa S
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 118 Issue: 2 Pages: 275-287
- DOI
  10.1254/jphs.11166FP
- NAID
  10030455160
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Journal Article] Nicotine- and Tar-Free Cigarette Smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase2012
- Author(s)
  Asano H, Horinouchi T, Mai Y, Sawada O, Fujii S, Nishiya T, Minami M, Katayama T, Iwanaga T, Terada K, Miwa S.
- Journal Title
  
  J. Phar macol. Sci
  
  Volume: 118(2) Pages: 275-287
- NAID
  10030455160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Journal Article] Nicotine-and tar-free cigarette smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase2012
- Author(s)
  Asano H., Horinouchi T., Mai Y., Sawada O., Fujii S., Nishiya T., Minami M., Katayama T., Iwanaga T., Terada K. and Miwa S.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 118 Pages: 275-287
- NAID
  10030455160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Adenylate cyclase-cAMP-protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca2+ entry mediated via TRPC6 channels2012
- Author(s)
  Horinouchi T., Higa T., Aoyagi H., Nishiya T., Terada K. and Miwa S.
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 340 Pages: 143-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Adenylate cyclase-cAMP-protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca2+ entry mediated via TRPC6 channels2012
- Author(s)
  Horinouchi T, Higa T, Aoyagi H, Nishiya T, Terada K, Miwa S
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 340(1) Issue: 1 Pages: 143-151
- DOI
  10.1124/jpet.111.187500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066, KAKENHI-PROJECT-24390059, KAKENHI-PROJECT-24590309
[Journal Article] Regulation of inducible nitric-oxide synthase by the SPRY domain-and SOCS box-containg Proteins2011
- Author(s)
  Nishiya T, et al.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 286 Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590052
[Journal Article] Regulation of inducible nitric oxide synthase by the SPRY domain- and SOCS box-containing proteins2011
- Author(s)
  Nishiya T, et al
- Journal Title
  
  J.Biol.Chem
  
  Volume: 286 Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] The ECS(SPSB) E3 ubiquitin ligase is the master regulator of the lifetime of inducible nitric-oxide synthase2011
- Author(s)
  Matsumoto K., Nishiya T., Maekawa S., Horinouchi T., Ogasawara K., Uehara T and Miwa S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 409 Pages: 46-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article]2011
- Author(s)
  Matsumoto K, Nishiya T, Maekawa S, Horinouchi T, Ogasawara K, Uehara T, Miwa S
- Journal Title
  
  Biochem.Biophys.Res.Commun. 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] The ECS (SPSB) E3 ubiquitin ligase is the master regulator of the lifetime of inducible nitric-oxide synthase. Biochem2011
- Author(s)
  Matsumoto, K., Nishiya, T., Maekawa, S., Horinouchi, T., Ogasawara, K., Uehara, T., and Miwa, S
- Journal Title
  
  Biophys. Res. Commun
  
  Volume: 409 Issue: 1 Pages: 46-51
- DOI
  10.1016/j.bbrc.2011.04.103
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23590066, KAKENHI-PROJECT-23659041
[Journal Article] Regulation of inducible nitric oxide synthase by the SPRY domain- and SOCS box-containing proteins.2011
- Author(s)
  Nishiya T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article]2011
- Author(s)
  Nishiya T, Uehara T
- Journal Title
  
  Nitric Oxide 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article]2011
- Author(s)
  Nishiya T, Matsumoto K, Maekawa S, Kajita E, Horinouchi T, Fujimuro M, Ogasawara K, Uehara T, Miwa
- Journal Title
  
  S.J.Biol.Chem. 286
  
  Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] SSPRY domain-containing SOCS box protein-1 (SPSB1), SPSB2, and SPSB4 are master regulators of proteasome-dependent degradation of iNOS.2011
- Author(s)
  Nishiya, T.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] Screening systems for the identification of S-nitrosylated proteins2011
- Author(s)
  Uehara T, Nishiya T
- Journal Title
  
  Nitric Oxide
  
  Volume: (In press,In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590052
[Journal Article] Regulation of inducible nitric oxide synthase by the SPRY domain- and SOCS box-containing proteins2011
- Author(s)
  Nishiya T, Matsumoto K, Maekawa S, Kajita E, Fujimuro M, Ogasawara K, Uehara T, Miwa S
- Journal Title
  
  J Biol Chem 286
  
  Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590052
[Journal Article] Regulation of inducible nitric-oxide synthase by the SPRY domain-and SOCS box-containing proteins2011
- Author(s)
  Nishiya T., Matsumoto K., Maekawa S., Kajita E., Horinouchi T., Fujimuro M., Ogasawara K., Uehara T. and Miwa S.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)2011
- Author(s)
  Numajiri N., Takasawa K., Nishiya T., Tanaka H., Ohno K., Hayakawa W., Asada M., Matsuda H., Azumi K., Kamata H., Nakamura T., Hara H., Minami M., Lipton S.A., Uehara T.
- Journal Title
  
  Proceedings of the National Academy of Sciences, USA
  
  Volume: 108 Issue: 25 Pages: 10349-10354
- DOI
  10.1073/pnas.1103503108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08471, KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23590066, KAKENHI-PROJECT-23659041
[Journal Article] Screening systems for identification of S-nitrosylated proteins2011
- Author(s)
  Uehara, T. and Nishiya, T
- Journal Title
  
  Nitric Oxide
  
  Volume: 25 Issue: 2 Pages: 108-111
- DOI
  10.1016/j.niox.2010.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23659041
[Journal Article] SPRY domain-containing SOCS box protein-1 (SPSB1), SPSB2, and SPSB4 are master regulators of proteasome-dependent degradation of iNOS2011
- Author(s)
  Nishiya, T., Matsumoto, K., Maekawa, S., Horinouchi, T., Fujimuro, M., Ogasawara, K., Uehara, T., and Miwa, S
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Issue: 11 Pages: 9009-9019
- DOI
  10.1074/jbc.m110.190678
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-22390370, KAKENHI-PROJECT-23659041, KAKENHI-PROJECT-23659291
[Journal Article] Function and Regulation of Endothelin Type A Receptor-Operated Transient Receptor Potential Canonical Channels2011
- Author(s)
  Horinouchi T, Terada K, Higa T, Aoyagi H, Nishiya T, Suzuki H, Miwa S
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 117 Issue: 4 Pages: 295-306
- DOI
  10.1254/jphs.11162FP
- NAID
  10030453850
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Journal Article] Function and regulation of endothelin type A receptor-operated transient receptor potential canonical channels2011
- Author(s)
  Horinouchi T, Terada K, Higa T, Aoyagi H, Nishiya T, Suzuki H, Miwa S.
- Journal Title
  
  J . Phar macol. Sci
  
  Volume: 117(4) Pages: 295-306
- NAID
  10030453850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of PTEN2011
- Author(s)
  Numajiri N, Takasawa K, Nishiya T, Tanaka H, Ohno K, Hayakawa W, Asada M, Matsuda H, Azumi K, Kamata H, Nakamura T, Hara H, Minami M, Lipton S, Uehara T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 108(25)(*Equal contribution) Pages: 10349-10354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Journal Article] Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.2010
- Author(s)
  Nishimoto A., Lu L., Hayashi M., Nishiya T., Horinouchi T. and Miwa S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 391 Pages: 1616-1622
- NAID
  120001909636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Endothelin type Breceptor-induced sustained Ca2+ influx involves G(q/11)/phospholipase C-independent, p38 mitogen-activated protein kinase-dependent activation of Na+/H+ exchanger.2010
- Author(s)
  Higa T., Horinouchi T., Aoyagi H., Asano H., Nishiya T., Nishimoto A., Muramatsu I. and Miwa S.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 113 Pages: 276-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Differential coupling of human endothelin type A receptor to G(q/11) and G(12) proteins : the functional significance of receptor expression level in generating multiple receptor signaling.2009
- Author(s)
  Horinouchi T., Asano H., Higa T., Nishimoto A., Nishiya T., Muramatsu I. and Miwa S.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 111 Pages: 338-351
- NAID
  130000132483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Miwa S、Functional role of Na+/H+ exchanger in Ca2+ influx mediated via human endothelin type A receptor stably expressed in Chinese hamster ovary cells2008
- Author(s)
  Horinouchi T, Miyake Y, Nishiya T, Nishimoto A, Morishima S, Muramatsu I
- Journal Title
  
  J Pharmacol Sci 107(4)
  
  Pages: 456-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Characterization of noradrenaline-induced increases in intracellular Ca^<2+> levels in Chinese hamster ovary cells stablyexpressing human α1A-adrenoceptor2007
- Author(s)
  Horinouchi T, Miyake Y, Nishiya T, Nishimoto A, Yorozu S, Jinno A, Kajita E, Miwa S
- Journal Title
  
  J Pharmacol Sci 105(1)
  
  Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Endothelin-1 decreases [Ca^<2+>]i via Na^+/Ca^<2+> exchanger in CHO cells stably expressing endothelin ETA receptor2007
- Author(s)
  Horinouchi T, Nishimoto A, Nishiya T, Lu L, Kajita E, Miwa S
- Journal Title
  
  Eur J Pharmacol 566(1-3)
  
  Pages: 28-33
- NAID
  120000965254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] 循環系調節因子としてのエンドセリンにより活性化される細胞内カルシウムシグナルとその調節系2007
- Author(s)
  三輪聡一、堀之内孝広、西本新、西屋禎
- Journal Title
  
  適応医学 11(2)
  
  Pages: 34-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN22007
- Author(s)
  Maekawa S, Mori D, Nishiya T, Takikawa O, Horinouchi T, Nishimoto A, Kajita E, Miwa S
- Journal Title
  
  Biochim Biophys Acta (Mol Cell Res) 1773(6)
  
  Pages: 1000-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD882007
- Author(s)
  Nishiya T, et. al.
- Journal Title
  
  FEBS Lett 581
  
  Pages: 3223-3229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD882007
- Author(s)
  Nishiya T, Kajita E, Horinouchi T, Nishimoto A, Miwa S
- Journal Title
  
  FEBS Lett 581(17)
  
  Pages: 3223-3229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Ligand-independent oligomerization of TLR4 regulated by a short hydrophobic region adjacent to the transmembrane domain2006
- Author(s)
  Nishiya T, Kajita E, Miwa S
- Journal Title
  
  Biochem Biophys Res Commun 341(4)
  
  Pages: 128-1134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] The transmembrane domain directs TLR9 to intracellular compartments that contain TLR32006
- Author(s)
  Kajita E, Nishiya T, Miwa S
- Journal Title
  
  Biochem Biophys Res Commun 343(2)
  
  Pages: 578-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN22006
- Author(s)
  Nagai K, Takikawa O, Kawakami N, Fukao M, Soma T, Oda A, Nishiya T, Hayashi M, Lu L, Nakano M, Kajita E, Fujita H, Miwa S
- Journal Title
  
  Arch Biochem Biophys 452(1)
  
  Pages: 29-37
- NAID
  120000960814
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] The ECS(SPSB) E3 ubiquitin ligase is the master regulator of the lifetuime of inducible nitric-oxide synthase
- Author(s)
  Nishiya T, Matsumoto K, Maekawa S, Kajita E, Fujimuro M, Ogasawara K, Uehara T, Miwa S
- Journal Title
  
  Biochem Biophys Res Commun 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590052
[Journal Article] Screening systems for the identification of S-nitrosylated proteins
- Author(s)
  Uehara T, Nishiya T.
- Journal Title
  
  Nitric Oxide 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590052
[Journal Article] NKG2D^+IFN-^+CD8^+T cells are responsible for palladium allergy
- Author(s)
  Kawano M, Nakayama M, Aoshima Y, Nakamura K, Ono M, Nishiya T, Nakamura S, Takeda Y, Dobashi A, Takahashi A, Endo M, Ito A, Ueda K, Sato N, Higuchi S, Kondo T, Hashimoto S, Watanabe M, Watanabe M, Takahashi T, Sasaki K, Nakamura M, Sasazuki T, Narushima T, Suzuki R, Ogasawara K.
- Journal Title
  
  PLoS One
  
  Volume: 9(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] E3ユビキチンリガーゼECS(SPSB3)の基質同定2016
- Author(s)
  緒方沙樹、篠原瑠奈、西屋禎
- Organizer
  第55回日本薬学会東北支部大会
- Place of Presentation
  奥羽大学
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460068
[Presentation] 新規E3ユビキチンリガーゼECS(SPSB)の基質同定2014
- Author(s)
  西屋禎、丸山拳、高澤孔明、浜田恭平、上原孝
- Organizer
  第134回日本薬学会年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] E3ユビキチンリガーゼECS(SPSB)による転写制御因子FOG-2の寿命制御2014
- Author(s)
  丸山拳、西屋禎、上原孝
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-26460068
[Presentation] E3ユビキチンリガーゼECS(SPSB)の新規基質の網羅的探索2014
- Author(s)
  西屋禎、丸山拳、高澤孔明、浜田恭平、上原孝
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] E3ユビキチンリガーゼECS(SPSB)の新規基質の網羅的探索2014
- Author(s)
  西屋禎、丸山拳、高澤孔明、浜田恭平、上原孝
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター、仙台市
- Year and Date
  2014-03-19
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] 新規E3ユビキチンリガーゼECS(SPSB)の基質同定2014
- Author(s)
  西屋禎、丸山拳、高澤孔明、浜田恭平、上原孝
- Organizer
  第134回日本薬学会年会
- Place of Presentation
  熊本大学、熊本市
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] E3ユビキチンリガーゼ"ECS(SPSB)"の新規基質の網羅的同定2013
- Author(s)
  西屋禎、丸山拳、高澤孔明、浜田恭平、松本一馬、小笠原康悦、三輪聡一、上原孝
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] タンパク質S-ニトロシル化／酸化を介したによる小胞体ストレス誘導機構2013
- Author(s)
  柴田万里，西屋　禎，上原　孝
- Organizer
  日本薬学会第１３３回年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] SPSBファミリー蛋白質を介したCDC14A phosphataseのユビキチン-プロテアソーム依存的分解機構2013
- Author(s)
  西屋禎、丸山拳、松本一馬、小笠原康悦、三輪聡一、上原孝
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡市
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] SPSBファミリー蛋白質を介したCDC14A phosphataseのユビキチン－プロテアソーム依存的分解機構2013
- Author(s)
  西屋　禎　他
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] E3ユビキチンリガーゼ“ECS(SPSB)”の新規基質の網羅的同定2013
- Author(s)
  西屋禎、丸山拳、高澤孔明、浜田恭平、松本一馬、小笠原康悦、三輪聡一、上原孝
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] SPSB ファミリー蛋白質を介したCDC14A phosphatase のユビキチン－プロテアソーム依存的分解機構2013
- Author(s)
  西屋　禎，丸山　拳，松本一馬，小笠原康悦，三輪聡一，上原　孝
- Organizer
  第８６回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] CDC14AはElongin B/C-Cul5-SPSB型E3ユビキチンリガーゼの基質である2012
- Author(s)
  西屋　禎　他
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] CDC14AはElongin B/C-Cul5-SPSB型E3ユビキチンリガーゼの基質である2012
- Author(s)
  西屋禎、松本一馬、小笠原康悦、三輪聡一、上原孝
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡、福岡市
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] ニトロソ化/酸化ストレスによる小胞体蛋白質の機能不全2012
- Author(s)
  柴田万里, 西屋禎, 上原孝
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 新規iNOS分解系の発見とその心血管系への治療標的としての可能性2011
- Author(s)
  西屋禎
- Organizer
  第21回日本循環薬理学会(招待講演)
- Place of Presentation
  岡山大学（岡山市）
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] iNOS regulation by the SPRY domain- and SOCS box-containing proteins (SPSBs) in macrophages2011
- Author(s)
  西屋禎
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] 誘導型NO合成酵素の分解制御機構2011
- Author(s)
  西屋禎、前川聡、松本一馬、堀之内孝広、藤室雅弘、小笠原康悦、上原孝、三輪聡一
- Organizer
  第11回日本NO学会
- Place of Presentation
  昭和薬科大学、東京
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] 誘導型NO合成酵素のユビキチン・プロテアソーム依存的分解制御機構2011
- Author(s)
  松本一馬、西屋禎、前川聡、堀之内孝広、藤室雅弘、小笠原康悦、上原孝、三輪聡一
- Organizer
  第25回北海道薬物作用談話会
- Place of Presentation
  酪農学園大学中央館学生ホール、江別市
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] PRY domainとSOCS boxタンパク質による誘導型-酸化窒素合成酵素の分解制御機構2011
- Author(s)
  西屋禎
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] 誘導型NO合成酵素の分解制御機構2011
- Author(s)
  西屋禎
- Organizer
  第11回日本NO学会
- Place of Presentation
  昭和薬科大学（東京都）
- Data Source
  KAKENHI-PROJECT-23590066
[Presentation] SPRY domainとSOCS boxタンパク質による誘導型一酸化窒素合成酵素の分解制御機構2011
- Author(s)
  西屋禎
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  震災のため,誌上開催
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] The SPRY domain-containing SOCS box protein family regulates the lifetime of iNOS by linking iNOS with Elongin BC-Cul5-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
  西屋禎
- Organizer
  The 14^<th> International Congress of Immunology (ICI2010)
- Place of Presentation
  神戸
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] The life time of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the elongin BC-Cu15-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
  Nishiya, T.
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] The lifetime of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the elongin BC-Cu15-Rbx2 E3 ubiquitin ligase complex.2010
- Author(s)
  Nishiya T, et al.
- Organizer
  The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide (NO2010)
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] Elongin B/C、Cul5、Rbx2、及びSPRY domain-containing SOCS box protein (SSB)により構成されるE3ユビキチンリガーゼ複合体(ECS-SSB)は誘導型一酸化窒素合成酵素(iNOS)の分解制御システムである2010
- Author(s)
  西屋禎
- Organizer
  第33回日本分子生物学会年会、第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] Elongin B/C、Cu15、Rbx2、及びSPRY domain-containing SOCS box protein (SSB)により構成されるE3ユビキチンリガーゼ複合体(ECS-SSB)は誘導型一酸化窒素合成酵素(iNos)の分解制御システムである2010
- Author(s)
  西屋禎, 他
- Organizer
  第33回日本分子生物学会-第83回日本生化学会合同年会
- Place of Presentation
  ポートピアホテル、神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] Elongin B/C,Cu15,Rbx2,及びSPRY domain-containing SOCS box protein(SSB)により構成されるE3ユビキチンリガーゼ複合体(ECS-SSB)は誘導型一酸化窒素合成酵素(iNOS)の分解制御システムである2010
- Author(s)
  西屋禎
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] The SPRY domain-containing SOCS box protein family regulates the lifetime of iNOS by Iinking iNOS with elongin BC-Cu15-Rbx2 E3 ubiquitin ligase complex.2010
- Author(s)
  Nishiya T, et al.
- Organizer
  The 14^<th> International Congress of Immunology(ICI2010)
- Place of Presentation
  Portopia Hotel, Kobe
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] The SPRY domain-containing SOCS box protein family regulates the lifetime of iNOS by linking iNOS with elongin BC-Cu15-Rbx2 E3 ubiquitin ligase complex.2010
- Author(s)
  Nishiya, T.
- Organizer
  The 14th International Congress of Immunology (ICI2010)
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] The lifetime of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the Elongin BC-Cul5-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
  西屋禎
- Organizer
  The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide (NO2010)
- Place of Presentation
  京都
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590052
[Presentation] The life time of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the elongin BC-Cul5-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
  Tadashi Nishiya, Satoshi Maekawa, Masahiro Fujimuro, Kouetsu Ogasawara, Takashi Uehara, and Soichi Miwa
- Organizer
  The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] MyD88の細胞局在とシグナル伝達におけるTIRドメインどそれ以外の領域の機能的差異2008
- Author(s)
  西屋禎
- Organizer
  第128回日本薬学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD882007
- Author(s)
  Tadashi Nishiya
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] MyD88の細胞局在及びシグナル伝達におけるTIRドメインとnon-TIR領域の機能的差異2007
- Author(s)
  西屋禎
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390072

1. MIWA Soichi (40157706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. HORINOUCHI Takahiro (20307771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. NISHIMOTO Arata (90396325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. UEHARA Takashi (00261321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. TERADA Koji (70342722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 渡辺誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 遠藤康男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishiya Tadashi 西屋 禎

NISHIYA Tadashi 西屋 禎

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Elucidation of the physiological function of novel E3 ubiquitin ligase that induces the inactivation of constitutively active proteins by the proteasome-dependent degradationPrincipal Investigator

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Elucidation of the physiological function of iNOS degradation system by generating mice in which the SPSB inhibitor is expressed throughout the bodyPrincipal Investigator

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Study of the regulatory mechanism of ETAR and ETBR level by receptor binding protein and the relevance between clinical significance and endothelin receptor level.

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Molecular mechanism of nitric oxide/nitrosative stress implicating in onset of neurodegenerative disorders

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The identification and characterization of proteins that are S-nitrosylated during bacterial infection and sepsisPrincipal Investigator

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Search for novel signal molecules which are directly activated by endothelin receptor

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[Book] SIGNALING BY TOLL-LIKE RECEPTORS2008

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[Journal Article] Correlation Between Attenuation of Protein Disulfide Isomerase Activity Through S-Mercuration and Neurotoxicity Induced by Methylmercury.2015

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[Journal Article] NKG2D+ IFN-γ+ CD8+ T cells are responsible for palladium allergy.2014

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[Journal Article] Function and regulation of endothelin type A receptor-operated TRPC channels2012

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[Journal Article] Adenylate cyclase-cAMP-protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca^<2+> entry mediated via TRPC6 channels2012

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[Journal Article] Nicotine- and Tar-Free Cigarette Smoke Induces Cell Damage Through Reactive Oxygen Species Newly Generated by PKC-Dependent Activation of NADPH Oxidase2012

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[Journal Article] Nicotine- and Tar-Free Cigarette Smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase2012

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[Journal Article] Nicotine-and tar-free cigarette smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase2012

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Nishiya Tadashi 西屋禎

NISHIYA Tadashi 西屋禎